kidney disease: A disease involving the kidney.
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
519972 |
1. Apply sex-specific ruleNone |
519972 |
2. Check conditionsNone |
519972 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
956 |
4. Check minimum number of eventsNone |
956 |
5. Include endpointsNone |
956 |
6. Filter based on genotype QC (FinnGen only) |
912 |
Control definitions (FinnGen only)
- Control exclude
- N14_RENALTUB
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- N10-N16
- Name in latin
- Aliae nephropathiae tubulo-interstitiales
Similar endpoints
↥List of similar endpoints to
Other renal tubulo-interstitial diseases
based on the number of shared cases.
Similar with more cases:
- Renal tubulo-interstitial diseases
- All kidney diseases
- Genitourinary diseases
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 9679 | 7187 | 2383 |
| Only index persons | 6588 | 5004 | 1584 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.17 | 0.21 | 0.07 |
| Only index persons | 0.15 | 0.18 | 0.06 |
| Median age at first event (years) | |||
| Whole population | 38.03 | 34.69 | 47.32 |
| Only index persons | 22.72 | 20.14 | 30.86 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 912 | 684 | 228 |
| Unadjusted period prevalence (%) | 0.21 | 0.24 | 0.10 |
| Median age at first event (years) | 28.23 | 20.83 | 50.41 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
No data
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 956
- Matched controls
- 9559
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
59099
ICD-8 Finland
Infections of kidney, Other
+∞
307.7
376
*
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
37.8
307.7
259
93
204
Kela drug reimbursment
Leukemia lymphatica
16.3
212.8
195
148
59098
ICD-8 Finland
Infections of kidney, Alia definita
+∞
210.4
194
*
N18.9
ICD-10 Finland
Chronic kidney disease, unspecified
36.5
182.9
116
36
N15.1
ICD-10 Finland
Renal and perinephric abscess
+∞
165.5
154
*
N15.9
ICD-10 Finland
Renal tubulo-interstitial disease, unspecified
+∞
130.2
122
*
A12AA04
ATC
calcium carbonate; oral
67.4
114.6
63
10
127
Kela drug reimbursment
Transplant complication
44.2
110.2
66
16
KH1AE
NOMESCO Finland
Urinary tract ultrasound examination
11.3
101.6
112
111
A11CC03
ATC
alfacalcidol; systemic
26.9
100.8
70
28
KA1AE
NOMESCO Finland
Kidney ultrasound examination
21.5
92.3
70
35
L04AA06
ATC
mycophenolic acid; systemic
21.5
89.6
68
34
138
Kela drug reimbursment
Severe anaemia associated with chronic renal failure
450.6
84.4
83
*
123
Kela drug reimbursment
Chronic disorders of vitamin D metabolism
232.9
83.8
85
*
B03XA02
ATC
darbepoetin alfa; parenteral
26.9
73.6
51
20
J01MA02
ATC
ciprofloxacin; systemic
3.3
71.2
471
2179
59010
ICD-8 Finland
Infections of kidney, Pyelonephritis
+∞
69.6
66
*
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
4.4
66.9
196
528
N18.8
ICD-10 Finland
Other chronic renal failure
107.8
64.8
70
7
N17.9
ICD-10 Finland
Acute renal failure, unspecified
174.1
62.8
65
*
Z94.0
ICD-10 Finland
Kidney transplant status
220.7
60.8
62
*
TK800
NOMESCO Finland
Hemodialysis
79.7
59.9
67
9
Z49.1
ICD-10 Finland
Extracorporeal dialysis
292.5
54.8
55
*
A41.5
ICD-10 Finland
Sepsis due to other Gram-negative organisms
11.4
52.6
56
52
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
6.1
51.0
93
165
KAS10
NOMESCO Finland
Allogenic transplantation of kidney from cadaver donor
263.4
49.5
50
*
N13.3
ICD-10 Finland
Other and unspecified hydronephrosis
257.9
48.5
49
*
A49.9
ICD-10 Finland
Bacterial infection, unspecified
4.3
47.8
138
363
TPH90
NOMESCO Finland
Removal of fixed intravenous catheter
20.2
47.8
37
19
N18.0
ICD-10 Finland
End-stage renal disease
+∞
47.3
45
*
I15.1
ICD-10 Finland
Hypertension secondary to other renal disorders
129.0
46.2
49
*
137
Kela drug reimbursment
Uraemia requiring dialysis
+∞
45.2
43
*
PBL10
NOMESCO Finland
Construction of arteriovenous fistula from radial artery
447.1
43.6
43
*
N19
ICD-10 Finland
Unspecified kidney failure
12.1
42.3
43
37
Z49.0
ICD-10 Finland
Preparatory care for dialysis
425.2
41.5
41
*
N15.8
ICD-10 Finland
Other specified renal tubulo-interstitial diseases
+∞
40.9
39
*
L04AD01
ATC
ciclosporin; systemic
10.7
40.7
45
44
C03CA01
ATC
furosemide; systemic
2.7
40.3
310
1465
Y0699
ICD-8 Finland
Examination of the urinary and genital organs, Urinary organs. Does not include urine tests to determine endocrine and metabolic disorders (Y 00.99)
14.3
39.2
36
26
N39.0
ICD-10 Finland
Urinary tract infection, site not specified
3.1
38.7
197
747
190
Kela drug reimbursment
Lanthanum carbonate, sevelamer and sucroferric oxyhydroxide
203.0
38.1
39
*
J01EA01
ATC
trimethoprim; systemic
2.5
37.9
340
1721
KA2AT
NOMESCO Finland
Biopsy of transplanted kidney with ultrasound guidance
+∞
36.7
35
*
B05DA
ATC
Isotonic solutions
+∞
36.7
35
*
KA2AE
NOMESCO Finland
Ultrasound examination transplanted kidney
359.8
35.2
35
*
B05DB
ATC
Hypertonic solutions
+∞
34.6
33
*
KBV02
NOMESCO Finland
Cystoscopic insertion of stent into ureter
12.1
34.4
35
30
A41.0
ICD-10 Finland
Sepsis due to Staphylococcus aureus
11.0
34.2
37
35
V03AE01
ATC
polystyrene sulfonate; oral
58.0
33.5
39
7
R50.9
ICD-10 Finland
Fever, unspecified
2.9
32.6
183
728
L04AA01
ATC
[U] ciclosporin
12.7
32.5
32
26
5909X
ICD-9 Finland
Infections of kidney, Infection of kidney, unspecified
+∞
32.5
31
*
J01MA12
ATC
levofloxacin; systemic
2.7
32.1
204
865
Z49.2
ICD-10 Finland
Other dialysis
+∞
31.4
30
*
L04AD02
ATC
tacrolimus; systemic
39.5
30.4
38
10
N18.5
ICD-10 Finland
Chronic kidney disease, stage 5
+∞
30.4
29
*
5901A
ICD-9 Finland
Infections of kidney, Acute pyelonephritis
+∞
30.4
29
*
A41.9
ICD-10 Finland
Sepsis, unspecified
6.8
30.0
48
74
A41.8
ICD-10 Finland
Other specified sepsis
9.8
29.9
35
37
KH1BT
NOMESCO Finland
Urinary tract cathetrisation with X-ray guidance
154.7
28.8
30
*
UKC02
NOMESCO Finland
Cystoscopy
2.9
28.3
151
581
59000
ICD-8 Finland
Infections of kidney, Pyelonephritis chronica
+∞
28.3
27
*
59358
ICD-8 Finland
Other diseases of kidney and ureter, Morbi ureteris alii
+∞
28.3
27
*
V03AE02
ATC
sevelamer; oral
289.6
27.9
28
*
N30.0
ICD-10 Finland
Acute cystitis
2.6
27.4
196
876
KA3AT
NOMESCO Finland
Biopsy of kidney with ultrasound guidance
27.4
27.2
37
14
JN3AD
NOMESCO Finland
Abdominal CT examination
3.0
26.7
127
458
TPX10
NOMESCO Finland
Implantation of vascular injection port
6.0
26.5
48
84
B03XA01
ATC
erythropoietin; parenteral
37.9
26.3
33
9
N25.8
ICD-10 Finland
Other disorders resulting from impaired renal tubular function
+∞
26.2
25
*
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
2.7
26.2
157
642
Q61.2
ICD-10 Finland
Polycystic kidney, autosomal dominant
61.8
26.1
30
5
PG1DE
NOMESCO Finland
Other extensive ultrasound examination of artery
4.4
26.1
68
164
N12
ICD-10 Finland
Tubulo-interstitial nephritis, not specified as acute or chronic
45.7
25.6
31
7
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
2.4
25.2
213
1024
R31
ICD-10 Finland
Unspecified haematuria
3.3
24.6
100
328
E10.7
ICD-10 Finland
Type 1 diabetes mellitus, With multiple complications
7.0
23.9
37
55
320
Kela drug reimbursment
Lanthanum carbonate, sevelamer and sucroferric oxyhydroxide
128.2
23.7
25
*
5902A
ICD-9 Finland
Infections of kidney, Renal and perinephric abscess
+∞
23.0
22
*
JAK10
NOMESCO Finland
Laparotomy and insertion of peritoneal dialysis catheter
+∞
23.0
22
*
TK820
NOMESCO Finland
Peritoneal dialysis
+∞
22.0
21
*
J01CA08
ATC
pivmecillinam; oral
1.9
21.8
481
3286
B03XA03
ATC
methoxy polyethylene glycol-epoetin beta; parenteral
+∞
20.9
20
*
196
Kela drug reimbursment
Paricalcitol and cinacalcet
112.5
20.6
22
*
J01MA06
ATC
norfloxacin; oral
2.4
20.6
165
769
A10AB05
ATC
insulin aspart; parenteral
3.3
20.5
83
271
N11.9
ICD-10 Finland
Chronic tubulo-interstitial nephritis, unspecified
+∞
19.9
19
*
TKC20
NOMESCO Finland
Catheterisation of bladder
3.5
19.8
72
220
L97
ICD-10 Finland
Ulcer of lower limb, not elsewhere classified
5.2
19.6
41
82
N20.0
ICD-10 Finland
Calculus of kidney
7.0
19.6
30
44
1530
FHL
Urethrocystoscopy
7.1
19.2
29
42
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
2.4
19.1
151
699
G04AB05, ,
ATC
4.5
18.9
47
109
59020
ICD-8 Finland
Infections of kidney, Abscess of kidney and perirenal tissue
+∞
18.8
18
*
TJA35
NOMESCO Finland
Removal of peritoneal dialysis catheter
+∞
18.8
18
*
KH1FT
NOMESCO Finland
Exchange of urinary catheter with radiological guidance
+∞
18.8
18
*
L04AX01
ATC
azathioprine; systemic
3.8
18.5
58
160
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.9
18.5
409
2751
R33
ICD-10 Finland
Retention of urine
3.4
18.2
69
216
N02AX02
ATC
tramadol; systemic, rectal
1.8
18.1
412
2790
TPH07
NOMESCO Finland
Cathetrisation of artery
2.6
17.8
108
441
A06AD11
ATC
lactulose; oral
2.3
17.8
151
720
TPH04
NOMESCO Finland
Cathetrisation of vein
2.1
17.7
208
1129
KH1AD
NOMESCO Finland
CT of urinary organs
4.7
17.6
41
90
KA9AE
NOMESCO Finland
Ultrasound examination transplanted kidney
183.2
17.6
18
*
QDB10
NOMESCO Finland
Major dressing of wound of skin of lower limb
3.7
17.4
57
162
A10AC01
ATC
insulin (human); parenteral
2.8
17.4
90
338
H05BX01
ATC
cinacalcet; oral
35.7
16.7
21
6
N08.2*D89.80
ICD-10 Finland
Immunoglobulin A (IgA) nephropathy
91.7
16.6
18
*
TK810
NOMESCO Finland
Hemofiltration
172.9
16.5
17
*
PBL09
NOMESCO Finland
Construction of arteriovenous fistula from brachial artery
172.9
16.5
17
*
J01EE01
ATC
sulfamethoxazole and trimethoprim; systemic
3.2
16.3
68
226
A28
ICPC
Limited function/disability NOS
2.2
16.2
151
747
M04AA01
ATC
allopurinol; systemic
2.6
16.0
102
426
J01DB01
ATC
cefalexin; oral
2.0
15.8
783
6600
N13.9
ICD-10 Finland
Obstructive and reflux uropathy, unspecified
+∞
15.7
15
*
N11.8
ICD-10 Finland
Other chronic tubulo-interstitial nephritis
+∞
15.7
15
*
V03AE03
ATC
lanthanum carbonate; oral
162.5
15.5
16
*
U14
ICPC
Kidney symptom/complaint
13.3
15.2
26
20
A10AE04
ATC
insulin glargine; parenteral
2.6
14.9
90
366
205
Kela drug reimbursment
Chronic hypertension
1.9
14.7
226
1339
SPAT1262
SPAT
Handing over of treatment supplies
2.1
14.6
155
805
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
2.4
14.5
101
440
XPX99
NOMESCO Finland
Other diagnostic examination of periferal vessel
3.1
14.5
63
215
H02AB04
ATC
methylprednisolone; systemic
2.1
14.3
153
796
KBV00
NOMESCO Finland
Insertion of stent into ureter
27.6
14.3
19
7
C02AC05
ATC
moxonidine; oral
3.7
14.2
45
125
J18.9
ICD-10 Finland
Pneumonia, unspecified
1.9
14.1
218
1290
WX408
NOMESCO Finland
General anesthesy, balanced
1.8
14.0
243
1493
321
Kela drug reimbursment
Paricalcitol and cinacalcet
30.5
13.9
18
6
G04AC01, ,
ATC
3.6
13.9
46
132
E11.7
ICD-10 Finland
Type 2 diabetes mellitus, with multiple complications
3.6
13.9
46
132
N08.39*E11.2
ICD-10 Finland
Non-insulin-dependent diabetes mellitus - Diabetic nephropathy
17.9
13.9
21
12
L89
ICD-10 Finland
Decubitus ulcer and pressure area
6.3
13.8
23
37
U70
ICPC
Pyelonephritis/pyelitis
13.8
13.8
23
17
N20.1
ICD-10 Finland
Calculus of ureter
4.1
13.7
38
96
JN3BD
NOMESCO Finland
Extensive abdominal CT
2.4
13.6
99
440
N17.8
ICD-10 Finland
Other acute renal failure
+∞
13.6
13
*
N13.0
ICD-10 Finland
Hydronephrosis with ureteropelvic junction obstruction
+∞
13.6
13
*
JN4AD
NOMESCO Finland
Body CT examination
2.5
13.5
85
353
PG5RT
NOMESCO Finland
PTA of arterio-venous shunt for dialysis
141.9
13.5
14
*
Q61.3
ICD-10 Finland
Polycystic kidney, unspecified
26.2
13.4
18
7
Z71.3
ICD-10 Finland
Dietary counselling and surveillance
3.2
13.4
53
171
C08CA02
ATC
felodipine; oral
2.5
13.3
86
361
WX882
NOMESCO Finland
High dependency care
4.7
13.1
30
65
NK6QA
NOMESCO Finland
Measurement of bone density from two or more locations with X-ray
2.7
13.1
72
279
SPAT1255
SPAT
Intravenous administration of medicine
2.8
13.1
65
239
C09AA02
ATC
enalapril; systemic
2.0
13.0
168
934
M10.9
ICD-10 Finland
Gout, unspecified
3.2
13.0
52
169
N08.39*E10.2
ICD-10 Finland
Insulin-dependent diabetes mellitus - Diabetic nephropathy
50.7
12.9
15
*
J01FF01
ATC
clindamycin; systemic
1.8
12.7
250
1588
N30.9
ICD-10 Finland
Cystitis, unspecified
2.7
12.7
69
266
PD4DE
NOMESCO Finland
Lower extremity artery ultrasound examination with Doppler method
5.3
12.5
25
48
N17.0
ICD-10 Finland
Acute renal failure with tubular necrosis
+∞
12.5
12
*
A12AA12
ATC
[U] calcium acetate
+∞
12.5
12
*
KA3EB
NOMESCO Finland
Antegrade pyelography
+∞
12.5
12
*
A10AB01
ATC
insulin (human); parenteral
3.4
12.3
44
133
ZXD05
NOMESCO Finland
Urgent procedure
1.7
12.0
295
1992
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.7
12.0
347
2445
WX892
NOMESCO Finland
Monitored bed care
2.6
11.9
72
293
N03.9
ICD-10 Finland
Chronic nephritic syndrome, unspecified
47.3
11.9
14
*
E87.5
ICD-10 Finland
Hyperkalaemia
9.1
11.8
24
27
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
2.4
11.6
80
346
N28.9
ICD-10 Finland
Disorder of kidney and ureter, unspecified
23.2
11.6
16
7
R11
ICD-10 Finland
Nausea and vomiting
2.3
11.6
88
398
75348
ICD-8 Finland
Congenital anomalies of urinary system, Maleformationes ureteris aliae
121.4
11.4
12
*
58209
ICD-8 Finland
Chronic nephritis, Unspecified
121.4
11.4
12
*
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.7
11.4
261
1723
C08CA01
ATC
amlodipine; oral
1.7
11.4
309
2136
R60.0
ICD-10 Finland
Localized oedema
2.1
11.2
112
566
I50.9
ICD-10 Finland
Heart failure, unspecified
2.1
11.2
107
532
KBV12
NOMESCO Finland
Transluminal endoscopic removal of stent from ureter
11.3
11.1
20
18
TPH20
NOMESCO Finland
Insertion of central venous catheter through subclavian or brachiocephalic vein
4.3
11.1
28
66
E11.2
ICD-10 Finland
Type 2 diabetes mellitus, with renal complications
4.5
11.0
27
62
E10.9
ICD-10 Finland
Type 1 diabetes mellitus, Without complications
3.1
11.0
47
159
E11.8
ICD-10 Finland
Type 2 diabetes mellitus, with unspecified complications
2.3
11.0
87
401
AA1AD
NOMESCO Finland
CT of head and brain
1.7
10.9
226
1449
25000
ICD-8 Finland
Diabetes mellitus, Sine complicatione
3.7
10.9
34
94
UKB02
NOMESCO Finland
Retrograde ureteroscopy
15.7
10.8
17
11
A10AA02, ,
ATC
3.3
10.7
41
130
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
1.9
10.7
146
826
A10AA01, ,
ATC
3.6
10.5
35
101
XKD00
NOMESCO Finland
Uroflowmetry
2.2
10.5
94
456
PBM10
NOMESCO Finland
Closure of arteriovenous fistula of radial artery
+∞
10.4
10
*
Z99.2
ICD-10 Finland
Dependence on renal dialysis
+∞
10.4
10
*
T86.1
ICD-10 Finland
Kidney transplant failure and rejection
+∞
10.4
10
*
PBU84
NOMESCO Finland
Plastic repair of arteriovenous fistula from artery of upper extremity
+∞
10.4
10
*
C07AB07
ATC
bisoprolol; oral
1.6
10.3
398
2977
103
Kela drug reimbursment
Diabetes, insulin-treated
1.7
10.2
213
1367
N28.1
ICD-10 Finland
Cyst of kidney
5.4
10.1
20
38
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
2.2
10.1
91
442
215
Kela drug reimbursment
Diabetes, non-insulin-treated
1.8
10.1
190
1184
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
1.6
10.1
299
2101
E11.9
ICD-10 Finland
Type 2 diabetes mellitus, without complications
1.8
10.1
189
1177
I50.0
ICD-10 Finland
Congestive heart failure
2.6
9.9
58
232
Z3231
NOMESCO Finland
Registered nurse
1.7
9.9
242
1617
J01MA01
ATC
ofloxacin; systemic
2.2
9.8
83
393
J01DA01
ATC
[U] cefalexin
1.6
9.8
585
4808
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.5
9.7
477
3751
00920
ICD-8 Finland
Diarrhoeal disease, Gastroenteritis (acuta) (infectiosa)
3.3
9.7
36
112
K65.0
ICD-10 Finland
Acute peritonitis
10.2
9.5
18
18
E10.1
ICD-10 Finland
Type 1 diabetes mellitus, With ketoacidosis
10.2
9.5
18
18
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
2.0
9.4
102
531
U07
ICPC
Urine symptom/complaint other
2.4
9.4
65
282
TJA33
NOMESCO Finland
Percutaneous introduction of peritoneal dialysis catheter
+∞
9.4
9
*
PG5DE
NOMESCO Finland
Ultrasound examination of injection gate to artery or vein with Doppler method
+∞
9.4
9
*
JA3AT
NOMESCO Finland
Cathetrisation of abdominal cavity with ultrasound guidance
5.2
9.4
19
37
E10.2
ICD-10 Finland
Type 1 diabetes mellitus, With renal complications
12.5
9.4
16
13
H3603, E103,
ICD-10 Finland
12.5
9.4
16
13
59902
ICD-8 Finland
Other diseases of urinary tract, Infectiones tractuum urinariorum NUD
8.1
9.4
20
25
XF400
NOMESCO Finland
ECG with 12 standard connections
1.9
9.4
129
730
KA1FN
NOMESCO Finland
Isotope renography
21.9
9.4
13
6
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
1.9
9.4
122
678
C07AB02
ATC
metoprolol; systemic
1.7
9.3
173
1072
M10.0
ICD-10 Finland
Idiopathic gout
3.7
9.3
29
80
78559
ICD-8 Finland
Symptoms referable to abdomen and lower gastro-intestinal tract, Colica abdominalis NUD
3.1
9.2
37
121
212
Kela drug reimbursment
Gout
4.6
9.1
21
46
A46
ICD-10 Finland
Erysipelas
2.0
9.1
110
596
A10AB04
ATC
insulin lispro; parenteral
3.1
9.0
37
122
EBA15
NOMESCO Finland
Extraction of multiple teeth
3.2
9.0
36
117
J02AC01
ATC
fluconazole; systemic
1.5
8.9
405
3114
Z2446
NOMESCO Finland
Social worker
2.3
8.9
65
289
ZX120
NOMESCO Finland
Intravenous
2.1
8.9
87
436
D41.0
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Kidney
4.0
8.9
25
64
N02AA05
ATC
oxycodone; systemic
1.8
8.9
137
803
U02
ICPC
Urinary frequency/urgency
1.9
8.8
127
728
KBV15
NOMESCO Finland
Cystoscopic change of ureteral stent
50.5
8.7
10
*
KH1AA
NOMESCO Finland
Urinary tract X-ray examination without contrast
7.7
8.7
19
25
N05BA01
ATC
diazepam; systemic, rectal
1.9
8.6
124
711
I70.2
ICD-10 Finland
Atherosclerosis of arteries of extremities
2.3
8.6
65
294
H02AB06
ATC
prednisolone; systemic
1.5
8.5
420
3275
I15.0
ICD-10 Finland
Renovascular hypertension
27.8
8.5
11
*
KAC00
NOMESCO Finland
Nephrectomy
27.8
8.5
11
*
KA1MN
NOMESCO Finland
Glomerular filtration rate (GFR) Isotope mesurement
27.8
8.5
11
*
A02BC02
ATC
pantoprazole; systemic
1.5
8.5
606
5100
XCK10
NOMESCO Finland
Photography of fundus of eye
2.1
8.4
78
383
N18.4
ICD-10 Finland
Chronic kidney disease, stage 4
90.8
8.4
9
*
R4190
NOMESCO Finland
Nutritional therapy
3.0
8.4
36
122
N03AX16
ATC
[U] pregabalin
1.6
8.4
207
1381
J01XE01
ATC
nitrofurantoin; oral
3.8
8.4
25
67
Y83
ICD-10 Finland
Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
2.3
8.3
64
291
Q61.0
ICD-10 Finland
Congenital single renal cyst
+∞
8.3
8
*
PG5AC
NOMESCO Finland
Contrast examination of injection gate to artery or vein
+∞
8.3
8
*
59012
ICD-8 Finland
Infections of kidney, Pyelocystitis
+∞
8.3
8
*
N13.1
ICD-10 Finland
Hydronephrosis with ureteral stricture, not elsewhere classified
+∞
8.3
8
*
B01AA03
ATC
warfarin; systemic
1.8
8.3
139
834
XF655
NOMESCO Finland
Measurement of heart muscle perfusion with exercise
3.6
8.3
27
77
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
2.6
8.3
47
186
D64.9
ICD-10 Finland
Anaemia, unspecified
2.1
8.2
81
407
KC1EE
NOMESCO Finland
Ultrasound measurement of residual urine
2.1
8.2
83
421
ZXD30
NOMESCO Finland
Difficulties in perfomrming procedure
2.6
8.2
45
175
G04AA01, ,
ATC
7.6
8.2
18
24
R4110
NOMESCO Finland
Physiotherapy
1.6
8.1
236
1637
ZXE20
NOMESCO Finland
More than three and less than five hours
1.9
8.1
113
641
TPH30
NOMESCO Finland
Insertion of central venous catheter through periferal vein
6.9
8.1
19
28
A02BC01
ATC
omeprazole; systemic
1.6
8.1
241
1683
SPAT1137
SPAT
Taking care of patient’s/customer’s hygiene
2.5
8.0
48
195
E10.8
ICD-10 Finland
Type 1 diabetes mellitus, With unspecified complications
4.7
7.9
18
39
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.5
7.8
351
2675
30660
ICD-8 Finland
Special symptoms not elsewhere classified, Enuresis
45.3
7.7
9
*
I10
ICD-10 Finland
Essential (primary) hypertension
1.5
7.7
478
3877
SPAT1229
SPAT
Assessment of need for aid
2.2
7.7
62
288
J01EE02
ATC
sulfadiazine and trimethoprim; systemic
1.6
7.7
235
1648
XX1AT
NOMESCO Finland
Other puncture with ultrasound guidance
4.6
7.7
18
40
C08CA13
ATC
lercanidipine; oral
1.8
7.7
115
668
A10AE05
ATC
insulin detemir; parenteral
2.5
7.6
46
188
JA3BT
NOMESCO Finland
Cathetrisation of abdominal cavity with X-ray guidance
25.2
7.6
10
*
2500A
ICD-9 Finland
Diabetes mellitus without mention of complication[DIABETES MELLITUS SINE COMPLICATIONE,TYYPPI II]
3.3
7.6
28
87
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
1.6
7.5
177
1166
SPAT1263
SPAT
Sampling
1.5
7.4
361
2787
Q61.5
ICD-10 Finland
Medullary cystic kidney
80.7
7.4
8
*
KBJ10
NOMESCO Finland
Cutaneous ureteroenterostomy
80.7
7.4
8
*
WX204
NOMESCO Finland
Axillary plexus blockaced
2.8
7.4
37
137
C08CA05
ATC
nifedipine; systemic
2.3
7.4
57
260
A03
ICPC
Fever
1.7
7.4
150
950
S97
ICPC
Chronic ulcer skin
2.4
7.4
48
203
N30
ICD-10 Finland
Cystitis
2.0
7.3
82
432
R53
ICD-10 Finland
Malaise and fatigue
1.6
7.3
214
1482
E10.3
ICD-10 Finland
Type 1 diabetes mellitus, With ophthalmic complications
3.2
7.3
29
94
N15.0
ICD-10 Finland
Balkan nephropathy
+∞
7.3
7
*
KH1YT
NOMESCO Finland
Percutaneous implantation of endoprothesis with radiological guidance
+∞
7.3
7
*
7151
FHL
Kidney transplantation
+∞
7.3
7
*
5937A
ICD-9 Finland
Other disorders of kidney and ureter, Vesicoureteric reflux
+∞
7.3
7
*
N08.39
ICD-10 Finland
Glomerular disorders in diabetes mellitus microalbuminuria
+∞
7.3
7
*
C07AG02
ATC
carvedilol; oral
2.4
7.3
51
223
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
2.0
7.2
81
427
TQW11
NOMESCO Finland
Vacuum treatment of wound
3.7
7.2
22
60
OAB74
NOMESCO Finland
Nutritional guidance related to treatment and rehabilitation for medical condition
7.4
7.2
16
22
A04.7
ICD-10 Finland
Enterocolitis due to Clostridium difficile
3.6
7.2
23
65
J09
ICD-10 Finland
Influenza due to identified zoonotic or pandemic influenza virus
3.3
7.1
26
80
XKD06
NOMESCO Finland
Physiologic investigation of micturition
3.4
7.1
25
75
WX203
NOMESCO Finland
Infraclavicular plexus blockade
3.4
7.1
25
75
WX730
NOMESCO Finland
Conventional respirator
6.6
7.1
17
26
JN3CD
NOMESCO Finland
Abdominal CT examination both without and with contrast
3.0
7.1
30
101
N06AX21
ATC
duloxetine; oral
1.8
7.0
120
724
N02AJ06
ATC
codeine and paracetamol; systemic
1.5
7.0
363
2830
ZX108
NOMESCO Finland
Inhalation
13.9
6.9
11
8
R32
ICD-10 Finland
Unspecified urinary incontinence
3.2
6.9
26
82
WX000
NOMESCO Finland
Monitoring vital functions without anesthesy
2.5
6.8
41
167
XX4AT
NOMESCO Finland
Other canalization with ultrasound guidance
11.0
6.8
12
11
WYA30
NOMESCO Finland
Treatment of a patient needing special arrangements
2.0
6.8
75
394
E10
ICD-10 Finland
Type 1 diabetes mellitus
3.7
6.8
21
58
N05BA04
ATC
oxazepam; oral
1.5
6.8
234
1680
3025
Kela drug reimbursment
Calcium carbonate
40.3
6.8
8
*
T89
ICPC
Diabetes insulin dependent
2.6
6.8
38
150
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
1.5
6.7
252
1839
B99
ICD-10 Finland
Other and unspecified infectious diseases
3.9
6.7
19
49
N28.0
ICD-10 Finland
Ischaemia and infarction of kidney
22.7
6.7
9
*
U05
ICPC
Urination problems other
2.5
6.7
41
169
U01
ICPC
Dysuria/painful urination
2.0
6.7
69
354
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
1.8
6.6
103
604
Y83.9
ICD-10 Finland
Surgical procedure, unspecified as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
2.9
6.6
31
111
38100
ICD-8 Finland
Otitis media without mention of mastoiditis, Acute
3.0
6.6
29
100
H43.1
ICD-10 Finland
Vitreous haemorrhage
3.4
6.6
23
69
B34.9
ICD-10 Finland
Viral infection, unspecified
2.8
6.5
31
112
N02AB03
ATC
fentanyl; nasal, sublingual, transdermal
2.6
6.5
36
141
0384B
ICD-9 Finland
Septicaemia due to other gram-negative organisms[SEPTICHAEMIA E. COLI]
70.3
6.4
7
*
KH1AT
NOMESCO Finland
Urinary tract cathetrisation with ultrasound guidance
70.3
6.4
7
*
WW400
NOMESCO Finland
Plasmaferesis
70.3
6.4
7
*
K56.6
ICD-10 Finland
Other and unspecified intestinal obstruction
3.0
6.4
27
91
K21.0
ICD-10 Finland
Gastro-oesophageal reflux disease with oesophagitis
1.9
6.4
85
476
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
1.7
6.4
123
768
C09CA01
ATC
losartan; oral
1.5
6.4
200
1405
JN4BD
NOMESCO Finland
Extensive body CT
1.9
6.3
77
418
SPAT1167
SPAT
Insertion of urinary catheter
3.6
6.3
20
56
WX302
NOMESCO Finland
Thoracal epidural anesthesy
2.4
6.3
42
180
SPAT1148
SPAT
Treatment of chronic ulcer or burn
1.8
6.3
99
583
N18
ICD-10 Finland
Chronic kidney disease
9.3
6.3
12
13
N06AB10
ATC
escitalopram; oral
1.5
6.3
186
1289
WX002
NOMESCO Finland
Sedation and analgesia
1.6
6.3
156
1038
K56.5
ICD-10 Finland
Intestinal adhesions [bands] with obstruction
3.9
6.3
18
47
FM1LE
NOMESCO Finland
Combined ultrasound and EKG examination of heart with tolerance test
18.1
6.3
9
5
B25.8
ICD-10 Finland
Other cytomegaloviral diseases
18.1
6.3
9
5
59199
ICD-8 Finland
Hydronephrosis
+∞
6.3
6
*
N08.2
ICD-10 Finland
Glomerular disorders in blood diseases and disorders involving the immune mechanism
+∞
6.3
6
*
7531A
ICD-9 Finland
Congenital anomalies of urinary system, Cystic kidney disease
+∞
6.3
6
*
N03.8
ICD-10 Finland
Chronic nephritic syndrome, other
+∞
6.3
6
*
E10.00
ICD-10 Finland
Insulin-dependent diabetes diabetic hypoglycemic coma
7.1
6.2
14
20
P01AB01
ATC
metronidazole; oral, rectal
1.4
6.2
365
2896
F10.1
ICD-10 Finland
Mental and behavioural disorders due to use of alcohol, Harmful use
2.2
6.2
50
233
WZC00
NOMESCO Finland
Treatment plan or consultation
1.4
6.2
302
2316
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
1.8
6.2
93
541
R10.0
ICD-10 Finland
Acute abdomen
2.8
6.2
30
110
F32.10
ICD-10 Finland
Moderate depressive episode without somatic syndrome
1.9
6.2
76
415
B01AB10
ATC
tinzaparin; parenteral
1.9
6.1
81
452
B01AB04
ATC
dalteparin; parenteral
2.3
6.1
46
208
U71
ICPC
Cystitis/urinary infection other
2.0
6.1
63
323
IAZ97
NOMESCO Finland
Psychiatric consultation in another specialty
3.8
6.1
18
48
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
1.7
6.1
127
809
N05CD07
ATC
temazepam; oral
1.8
6.1
99
590
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
250
692
4.54
83.64
16.3
3.0
1.10
1.01
mmol/l
4.01
239
638
170
431
4.58
62.49
9.3
2.3
124.26
63.98
ng/l
6.92
153
385
89
129
7.50
59.36
6.2
3.1
1.90
1.10
mg/l
9.67
84
122
170
465
4.23
56.31
8.7
2.4
0.78
2.29
mmol/l
5.89
143
377
222
819
3.23
46.33
6.0
1.8
21.66
23.25
%
1.05
207
700
233
890
3.14
45.79
6.0
1.7
2.20
2.44
g/l
8.36
227
822
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
75
121
6.64
45.13
3.5
2.7
0.28
0.43
u/ml
1.36
34
62
380
1966
2.55
41.05
6.4
2.5
38.31
82.04
e6/l
0.67
310
1486
241
998
2.89
40.52
5.9
1.8
11.60
13.71
umol/l
5.18
236
927
348
1799
2.47
36.87
6.3
2.4
0.23
0.36
e6/l
1.25
283
1336
60
102
6.21
34.21
8.5
5.4
3209.73
129.31
iu/ml
0.77
15
13
132
425
3.44
33.75
1.5
1.5
—
—
—
0
0
82
197
4.46
31.66
3.0
1.8
1.64
1.37
g/l
1.64
75
168
485
3035
2.21
31.52
15.9
12.1
1.23
1.20
inr
0.29
146
924
527
3421
2.20
31.09
16.3
4.8
1.22
1.22
mmol/l
0.05
451
2887
56
98
6.01
30.99
2.2
1.3
123.71
119.21
u/ml
—
7
19
217
975
2.59
30.23
5.3
2.2
4.87
3.12
e6/l
0.63
129
494
214
958
2.59
30.02
2.2
1.7
—
—
—
0
0
406
2410
2.19
29.63
7.7
2.9
192.31
76.13
e6/l
1.09
325
1623
272
1372
2.37
29.37
4.8
2.1
4.21
7.04
e6/l
3.41
251
1226
215
992
2.51
28.14
2.8
1.8
29.93
29.37
s
0.69
210
961
70
165
4.50
27.64
1.6
1.4
—
—
—
0
0
462
2949
2.10
27.27
9.0
3.7
34.42
36.25
g/l
8.19
436
2738
219
1033
2.45
27.24
4.6
2.8
0.81
0.82
mmol/l
0.69
207
967
222
1058
2.43
26.97
5.0
2.1
1.73
1.00
e6/l
0.45
131
573
347
1996
2.16
26.84
5.3
2.8
6.78
7.61
mmol/l
2.90
305
1678
102
323
3.42
26.59
6.1
2.5
1.11
2.12
mmol/l
1.89
73
244
337
1928
2.15
26.34
5.8
3.3
28.51
5.37
mg/mmol
3.49
249
1160
106
346
3.32
26.33
6.0
2.5
5.03
5.20
kpa
1.45
101
332
154
628
2.73
25.77
4.1
3.9
263.31
242.08
u/l
0.37
149
584
651
4822
2.10
24.52
8.0
3.7
201.71
1105.91
e6/l
—
7
70
154
646
2.65
24.30
3.3
2.4
2.02
1.73
%
1.76
140
563
465
3064
2.01
24.24
14.9
4.4
1.22
1.22
mmol/l
1.06
433
2783
310
1771
2.11
23.89
2.6
2.0
3.12
3.03
mg/l
0.30
272
1484
29
34
8.76
22.86
1.5
1.3
—
—
—
0
0
152
658
2.56
22.40
2.0
1.6
—
—
—
0
0
314
1842
2.05
22.25
5.1
2.8
126.86
290.63
mg/l
0.96
242
1128
53
122
4.54
21.53
1.6
1.1
234.07
253.31
u/ml
0.17
41
65
513
3609
1.91
20.97
8.2
5.5
26.61
28.65
%
3.86
489
3384
150
666
2.49
20.88
2.1
1.7
—
—
—
0
0
495
3448
1.90
20.80
4.7
2.6
153.79
93.73
ug/l
6.69
471
3187
353
2205
1.95
20.60
3.5
2.2
56.94
95.82
u/l
0.54
329
2035
156
710
2.43
20.56
10.7
5.5
103.82
104.58
mmol/l
1.07
156
710
53
132
4.19
19.47
1.6
1.1
—
—
—
0
0
503
3573
1.86
19.38
7.8
5.3
58.10
56.74
%
1.65
478
3346
91
325
2.99
19.31
2.0
1.6
—
—
—
0
0
288
1719
1.97
18.91
3.6
2.2
2918.28
7275.73
umol/l
1.23
258
1499
514
3700
1.84
18.74
7.6
5.4
9.49
10.55
umol/l
2.45
495
3499
501
3590
1.83
18.43
6.2
3.2
0.00
0.00
estimate
0.50
111
716
506
3645
1.82
18.21
6.3
3.2
0.00
0.01
estimate
0.80
103
659
502
3608
1.82
18.20
8.1
4.4
0.00
0.00
estimate
0.50
108
675
17
0
+∞
17.76
12.1
0.0
5.14
—
mmol/l
—
17
0
448
3140
1.80
17.39
3.3
2.2
73.69
77.23
nmol/l
2.06
408
2838
89
335
2.83
17.15
6.4
2.5
117.02
127.81
g/l
4.05
89
328
44
106
4.30
16.88
1.6
1.3
—
—
—
0
0
44
106
4.30
16.88
1.6
1.3
—
—
—
0
0
110
469
2.52
16.56
2.5
2.3
65.85
67.27
g/l
0.97
104
427
260
1568
1.90
16.17
1.8
1.5
20.28
21.18
nmol/l
0.40
234
1328
409
2838
1.77
16.05
2.2
1.9
93.88
97.39
pmol/l
0.78
222
1433
51
143
3.71
15.92
2.1
3.5
39.11
29.50
mg/l
0.82
38
118
51
143
3.71
15.92
2.1
3.5
89.57
33.82
mg/l
1.29
38
117
75
274
2.88
15.26
13.3
7.8
24.07
24.61
mmol/l
0.75
68
265
532
4032
1.72
14.82
9.6
3.7
7.19
6.51
mmol/l
4.26
502
3754
42
108
4.02
14.80
1.4
1.5
—
—
—
0
0
562
4333
1.72
14.62
11.9
8.2
4.32
3.93
e9/l
3.96
514
3815
114
531
2.30
14.05
3.5
2.2
56.76
74.23
ml/min/173m2
3.57
62
207
353
2429
1.72
13.72
4.9
3.0
2.34
2.36
mmol/l
1.18
318
2167
124
607
2.20
13.55
2.7
2.3
31.57
34.58
u/l
0.45
104
505
204
1199
1.89
13.45
2.1
1.6
1206.52
1161.05
nmol/l
0.23
159
888
126
630
2.15
13.04
10.1
6.3
0.09
1.42
mmol/l
3.14
98
499
85
359
2.50
13.01
1.8
1.4
—
—
—
0
0
58
201
3.01
12.97
2.3
1.7
2.87
2.47
ug/l
0.06
51
175
691
5735
1.74
12.85
11.8
6.4
80.31
75.85
u/l
2.36
662
5369
111
532
2.23
12.76
2.3
2.6
10.86
10.44
g/l
0.46
105
489
373
2644
1.67
12.75
4.1
3.1
31.81
52.73
ng/l
0.72
247
1636
125
633
2.12
12.51
10.3
6.3
5.05
5.14
kpa
0.47
116
609
125
634
2.12
12.46
10.3
6.3
12.64
12.63
kpa
0.01
116
610
305
2061
1.70
12.42
2.4
2.0
132.43
195.93
u/l
1.19
289
1940
131
678
2.08
12.38
5.4
2.9
—
—
—
0
0
253
1676
1.69
10.86
3.2
2.1
—
—
—
0
0
116
603
2.05
10.79
2.4
2.0
0.20
0.22
g/l
1.62
107
564
384
2842
1.59
10.49
6.0
3.3
—
—
—
0
0
16
10
16.24
10.37
1.1
1.1
—
—
—
0
0
42
138
3.14
10.31
1.8
1.7
—
—
—
0
0
46
160
2.97
10.25
1.3
1.2
—
—
—
0
0
64
265
2.52
10.22
5.7
2.5
24.04
25.46
mmol/l
2.24
64
259
31
85
3.74
10.04
1.1
1.2
—
—
—
0
0
443
3419
1.55
9.89
3.1
2.3
—
—
—
0
0
39
127
3.16
9.72
3.4
1.7
121.04
130.50
g/l
1.56
28
92
37
117
3.25
9.68
4.6
1.7
15.33
16.09
%
0.56
23
51
52
201
2.68
9.55
1.8
1.2
—
—
—
0
0
667
5676
1.58
9.32
5.3
3.8
16.51
10.81
mm/h
13.08
622
5258
275
1928
1.60
9.21
6.6
3.5
0.00
0.01
estimate
0.88
101
667
258
1790
1.60
8.99
3.0
2.8
2733.89
969.02
ng/l
3.87
221
1483
58
244
2.47
8.98
2.4
1.8
—
—
—
0
0
22
52
4.31
8.69
1.4
1.2
1809.00
1580.10
e6/l
0.10
15
40
32
99
3.31
8.68
1.2
1.2
—
—
—
0
0
38
134
2.91
8.30
5.5
2.2
38.53
88.68
ug/min
0.63
29
82
118
676
1.85
8.22
2.4
1.9
415.83
377.68
nmol/l
0.70
109
619
56
242
2.40
8.20
1.6
1.5
0.03
0.09
iu/ml
0.44
13
42
53
224
2.45
8.14
2.1
1.7
—
—
—
0
0
221
1516
1.60
7.96
1.8
1.7
73232788.78
19447077.22
pmol/l
0.33
198
1265
54
235
2.38
7.79
1.6
1.8
0.23
0.22
g/l
0.38
54
226
839
7692
1.74
7.30
27.9
10.9
25.20
20.26
mg/l
3.83
744
5910
7
0
+∞
7.30
4.7
0.0
—
—
—
0
0
19
46
4.19
7.29
1.5
1.2
10464.50
152700.34
e6/l
0.61
12
29
602
5147
1.46
7.10
3.7
2.8
47.81
41.95
u/l
1.09
579
4846
324
2474
1.47
6.95
4.1
2.9
27.98
29.16
u/l
0.50
310
2362
53
242
2.26
6.88
1.6
1.7
1.20
1.17
g/l
0.25
53
232
44
187
2.42
6.72
2.5
2.8
—
—
—
0
0
223
1595
1.52
6.54
6.4
3.4
1.01
1.02
kg/l
1.80
37
224
43
187
2.36
6.26
3.0
2.1
3.43
3.46
g/l
0.04
43
177
92
535
1.80
6.11
2.4
2.3
7.94
6.68
ug/l
0.26
77
462
17
34
5.07
5.89
1.2
1.1
19.65
14.79
u/l
0.33
17
29
123
784
1.65
5.88
3.2
2.5
5.98
6.79
umol/l
0.36
105
679
179
1248
1.53
5.86
4.5
3.3
168.88
327.11
ng/l
0.98
141
881
32
125
2.61
5.84
1.8
1.6
—
—
—
0
0
96
577
1.74
5.70
11.2
3.0
1.22
1.23
mmol/l
1.01
88
487
26
93
2.85
5.60
1.2
1.1
—
—
—
0
0
210
1537
1.47
5.41
1.6
1.4
2.17
2.23
g/l
0.20
136
947
22
74
3.02
5.28
3.0
1.5
89.40
90.11
%
0.16
22
74
32
133
2.45
5.17
3.9
3.3
4.21
4.31
e9/l
0.07
32
133
30
121
2.53
5.16
2.1
1.3
—
—
—
0
0
226
1692
1.44
5.15
1.9
1.7
1.27
0.95
mg/l
1.06
172
1265
21
70
3.04
5.12
2.2
1.7
—
—
—
0
0
8
6
13.43
5.08
1.4
3.0
—
—
—
0
0
39
181
2.20
4.93
1.8
2.2
0.49
0.80
g/l
0.39
33
163
29
118
2.50
4.91
2.2
1.7
—
—
—
0
0
18
56
3.26
4.91
6.1
2.4
—
—
—
0
0
32
137
2.38
4.87
4.6
3.6
58.69
57.20
%
0.25
32
137
16
38
4.26
4.83
1.1
1.1
—
—
—
0
0
762
7004
1.43
4.73
7.0
5.0
40.72
38.83
mmol/mol
4.76
713
6529
34
152
2.28
4.71
2.1
1.7
—
—
—
0
0
21
74
2.88
4.68
2.7
1.7
32.33
32.57
pg
0.06
21
74
834
7808
1.53
4.64
30.9
12.0
139.21
139.70
mmol/l
6.95
815
7598
19
64
3.01
4.57
2.3
1.8
—
—
—
0
0
34
155
2.24
4.51
2.1
1.7
—
—
—
0
0
835
7831
1.52
4.48
31.7
12.0
3.99
3.94
mmol/l
5.78
814
7611
15
37
4.10
4.41
2.8
1.8
—
—
—
0
0
25
100
2.54
4.40
2.2
3.2
0.92
0.77
nmol/l
0.36
18
78
11
20
5.55
4.29
2.0
2.0
—
—
—
0
0
11
20
5.55
4.29
2.0
2.0
—
—
—
0
0
176
1302
1.43
4.22
3.5
2.6
2.46
2.44
mmol/l
1.07
142
1159
11
21
5.29
4.15
2.0
2.0
—
—
—
0
0
57
324
1.81
4.14
1.1
1.3
0.28
1.73
u/ml
—
5
30
779
7247
1.40
4.01
24.2
10.0
74.57
84.55
ml/min/173m2
18.49
662
5909
16
53
3.05
3.97
2.1
1.6
—
—
—
0
0
16
53
3.05
3.97
2.1
1.6
—
—
—
0
0
16
53
3.05
3.97
2.1
1.6
—
—
—
0
0
7
8
8.80
3.77
2.0
2.1
—
—
—
0
0
6
5
12.06
3.76
2.0
1.0
133.50
75.60
ng/l
—
6
5
681
6227
1.33
3.75
4.5
4.1
14.63
14.58
pmol/l
0.23
624
5724
21
84
2.53
3.73
1.6
1.5
—
—
—
0
0
21
84
2.53
3.73
2.4
2.4
28.40
21.60
mg/l
—
10
22
40
210
1.94
3.72
1.8
2.0
3.88
3.47
g/l
1.17
35
195
40
210
1.94
3.72
1.8
2.0
—
—
—
0
0
40
210
1.94
3.72
1.8
2.0
7.45
7.29
g/l
0.22
35
195
38
196
1.98
3.72
1.8
2.0
3.39
2.85
g/l
1.64
32
181
15
51
2.97
3.58
2.5
1.6
—
—
—
0
0
24
105
2.32
3.54
2.0
1.6
—
—
—
0
0
24
105
2.32
3.54
2.0
1.6
—
—
—
0
0
792
7428
1.39
3.54
4.9
4.2
6.04
5.78
mmol/l
3.91
723
6833
228
1810
1.34
3.53
1.4
1.3
2.01
1.28
u/ml
0.40
56
473
11
26
4.27
3.51
2.7
2.8
—
—
—
0
0
50
289
1.77
3.48
2.5
1.8
—
—
—
0
0
75
484
1.60
3.46
2.7
2.6
239.99
173.24
ng/l
0.83
67
438
33
167
2.01
3.42
1.9
1.9
34.61
39.09
g/l
2.09
28
152
12
32
3.78
3.39
2.5
3.3
37041.67
38506.41
ug/l
0.23
12
32
23
101
2.31
3.38
1.5
1.5
—
—
—
0
0
8
14
5.75
3.34
1.8
1.3
—
—
—
0
0
17
65
2.64
3.31
8.2
3.6
—
—
—
0
0
11
28
3.96
3.29
2.1
1.8
—
—
—
0
0
11
28
3.96
3.29
2.1
1.8
—
—
—
0
0
34
177
1.95
3.27
1.2
1.2
—
—
—
0
0
6
7
8.61
3.26
2.0
1.4
—
—
—
0
0
46
266
1.77
3.21
1.3
2.0
—
—
—
0
0
36
194
1.89
3.14
1.8
2.0
11.59
10.06
g/l
1.63
31
179
12
36
3.36
3.02
1.2
1.1
—
—
—
0
0
20
87
2.33
3.02
1.6
1.5
—
—
—
0
0
120
881
1.41
3.00
1.8
1.8
1.51
1.39
%
1.02
106
793
5
5
10.04
2.98
1.2
1.6
—
—
—
0
0
18
75
2.43
2.98
1.6
1.5
—
—
—
0
0
76
511
1.53
2.97
3.0
3.4
4.48
4.54
pmol/l
0.12
67
446
188
1491
1.32
2.90
1.3
1.3
22.56
29.32
iu/ml
0.86
61
487
29
150
1.96
2.87
1.4
1.5
7250.80
16547.97
e6/l
0.90
20
115
121
897
1.40
2.87
4.9
3.9
31.35
32.46
%
0.56
92
623
10
28
3.60
2.79
2.2
2.5
—
—
—
0
0
(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
12
39
3.10
2.77
1.2
1.1
—
—
—
0
0
856
8219
1.40
2.57
14.9
9.1
23.73
24.94
u/l
1.87
836
7958
8
20
4.02
2.57
1.1
1.1
—
—
—
0
0
44
270
1.66
2.54
1.7
1.8
—
—
—
0
0
94
685
1.41
2.48
4.1
3.9
6.32
23.76
ug/l
0.84
78
560
38
226
1.71
2.47
1.3
1.3
—
—
—
0
0
10
32
3.15
2.44
1.1
1.1
24.00
22.69
u/l
—
10
32
10
32
3.15
2.44
1.1
1.1
88.50
80.78
u/l
—
10
32
767
7267
1.28
2.40
5.6
4.8
1.87
2.03
mu/l
0.47
719
6716
9
27
3.35
2.39
1.2
1.2
1560.22
1841.48
miu/ml
—
9
27
5
8
6.27
2.37
2.4
2.1
—
—
—
0
0
18
84
2.16
2.36
1.2
1.2
—
—
—
0
0
38
230
1.68
2.33
1.2
1.3
1.85
12.44
u/ml
—
6
47
20
98
2.06
2.32
1.9
1.6
—
—
—
0
0
797
7612
1.28
2.17
4.7
4.0
1.47
1.52
mmol/l
3.24
742
7083
16
74
2.18
2.15
1.4
1.4
69.00
54.65
%
—
9
48
6
14
4.31
2.15
1.2
1.1
—
—
—
0
0
17
81
2.12
2.13
2.2
1.7
—
—
—
0
0
812
7780
1.29
2.11
5.0
4.5
2.74
2.85
mmol/l
2.91
757
7237
11
43
2.58
2.08
2.3
1.5
—
—
—
0
0
6
15
4.02
2.04
1.0
1.1
—
—
—
0
0
6
15
4.02
2.04
1.2
1.3
—
—
—
0
0
10
38
2.65
2.00
1.1
1.1
—
—
—
0
0
771
7354
1.25
2.00
4.2
3.6
1.36
1.24
mmol/l
3.67
715
6793
10
39
2.58
1.94
2.0
1.5
—
—
—
0
0
889
8648
1.40
1.91
37.3
17.0
129.28
134.78
g/l
22.50
880
8529
798
7652
1.26
1.90
4.7
4.1
4.67
4.79
mmol/l
2.79
750
7162
7
22
3.20
1.88
2.1
1.7
—
—
—
0
0
16
79
2.04
1.86
1.2
1.1
—
—
—
0
0
888
8643
1.38
1.83
37.1
16.9
4.34
4.49
e12/l
13.58
870
8417
123
983
1.29
1.82
2.4
2.2
110.91
116.65
ug/g
0.09
92
769
887
8634
1.38
1.81
37.6
16.9
38.42
40.03
%
10.83
849
8118
7
23
3.06
1.80
1.0
1.2
—
—
—
0
0
887
8635
1.38
1.80
37.1
16.9
259.14
257.18
e9/l
0.37
871
8433
8
29
2.77
1.79
1.5
1.2
—
—
—
0
0
8
29
2.77
1.79
1.5
1.2
—
—
—
0
0
110
870
1.30
1.76
9.9
6.0
—
—
—
0
0
41
275
1.51
1.71
1.2
1.3
127.20
230.63
miu/ml
0.81
13
149
710
6751
1.20
1.70
31.8
13.4
15.02
14.71
%
0.81
698
6635
25
150
1.68
1.64
1.5
1.3
—
—
—
0
0
11
49
2.26
1.64
2.5
4.5
28.83
35.89
mu/l
0.16
11
49
5
14
3.58
1.61
1.2
1.2
—
—
—
0
0
8
33
2.44
1.54
1.6
1.5
—
—
—
0
0
106
852
1.27
1.52
1.6
1.8
—
—
—
0
0
17
93
1.84
1.52
1.0
1.1
5.60
5097.52
iu/ml
—
5
25
80
620
1.32
1.51
1.1
1.2
107.58
138.36
iu/ml
0.43
38
258
11
51
2.17
1.51
1.4
1.0
—
—
—
0
0
9
38
2.38
1.46
1.0
1.3
—
—
—
0
0
5
16
3.14
1.44
1.2
1.1
—
—
—
0
0
5
16
3.14
1.44
1.4
1.2
—
—
—
0
0
12
59
2.05
1.44
1.3
1.1
—
2.80
—
0
5
6
22
2.74
1.43
1.0
1.2
—
—
—
0
0
115
942
1.25
1.42
1.6
1.9
—
—
—
0
0
32
213
1.52
1.42
1.1
1.1
—
—
—
0
0
6
23
2.62
1.37
1.0
1.2
—
—
—
0
0
167
1437
1.20
1.29
1.3
1.3
8.55
11.84
u/ml
0.35
56
592
8
34
2.36
1.29
2.3
1.6
—
—
—
0
0
565
5332
1.15
1.28
3.6
3.2
—
—
—
0
0
8
35
2.30
1.27
2.3
1.5
—
—
—
0
0
8
35
2.30
1.27
1.5
1.3
—
—
—
0
0
8
35
2.30
1.27
1.5
1.3
—
—
—
0
0
8
36
2.23
1.24
1.4
1.2
—
—
—
0
0
12
63
1.92
1.23
1.4
1.3
—
—
—
0
0
5
19
2.64
1.21
1.4
1.1
—
—
—
0
0
14
78
1.81
1.21
1.9
1.6
—
—
—
0
0
14
78
1.81
1.21
1.9
1.6
—
—
—
0
0
14
79
1.78
1.17
1.1
1.1
—
—
—
0
0
24
356
0.67
1.17
1.3
1.5
—
—
—
0
0
10
51
1.97
1.11
1.0
1.2
—
—
—
0
0
10
51
1.97
1.11
1.0
1.2
—
—
—
0
0
10
51
1.97
1.11
2.3
1.6
—
—
—
0
0
12
207
0.57
1.11
1.3
1.3
—
—
—
0
0
24
160
1.51
1.10
1.8
1.5
10.89
6.22
e6/l
0.24
19
130
24
160
1.51
1.10
1.8
1.6
65.63
167.82
e6/l
0.89
19
135
7
139
0.50
1.10
1.4
1.7
—
—
—
0
0
5
21
2.39
1.09
1.2
1.8
—
—
—
0
0
5
21
2.39
1.09
1.2
1.8
—
—
—
0
0
9
165
0.54
1.09
1.1
1.4
—
—
—
0
0
10
52
1.93
1.06
1.8
1.2
—
—
—
0
0
10
52
1.93
1.06
1.1
1.4
1.85
1.55
nmol/l
—
10
43
15
90
1.68
1.04
1.7
1.3
—
—
—
0
0
5
22
2.28
1.03
1.4
1.0
41.78
30.38
u/ml
—
5
22
144
1649
0.85
1.02
1.4
1.4
—
—
—
0
0
33
241
1.38
0.97
1.2
1.2
—
—
—
0
0
15
92
1.64
0.97
1.7
1.3
—
—
—
0
0
15
92
1.64
0.97
1.7
1.3
—
—
—
0
0
33
242
1.38
0.95
1.2
1.2
—
—
—
0
0
27
374
0.71
0.95
1.4
1.4
—
—
—
0
0
29
209
1.40
0.93
1.2
1.3
11.22
13.01
u/l
0.23
16
161
13
208
0.62
0.92
1.2
1.4
—
—
—
0
0
13
208
0.62
0.92
1.2
1.4
—
—
—
0
0
9
52
1.74
0.92
1.1
1.4
—
—
—
0
0
9
52
1.74
0.92
1.3
1.4
—
—
—
0
0
6
28
2.15
0.91
3.0
1.3
—
—
—
0
0
13
207
0.62
0.91
1.2
1.3
—
—
—
0
0
14
86
1.64
0.91
1.1
1.3
—
—
—
0
0
16
104
1.55
0.85
1.2
1.4
7.64
7.34
mmol/l
0.17
16
89
6
32
1.88
0.82
1.3
1.1
128.38
157.75
iu/ml
—
6
32
12
73
1.65
0.82
1.0
1.1
—
—
—
0
0
69
574
1.22
0.81
1.2
1.4
27.31
28.81
iu/l
0.13
52
489
33
250
1.33
0.81
1.4
1.6
—
—
—
0
0
6
33
1.82
0.79
1.0
1.0
—
—
—
0
0
13
82
1.59
0.78
1.1
1.1
—
—
—
0
0
14
91
1.55
0.75
1.7
1.3
—
—
—
0
0
14
91
1.55
0.75
1.7
1.3
—
—
—
0
0
5
24
2.09
0.74
2.4
1.9
116.20
101.89
nmol/24h
—
5
24
5
24
2.09
0.74
3.6
5.5
—
—
—
0
0
9
55
1.64
0.73
1.4
1.2
—
—
—
0
0
31
237
1.32
0.73
5.2
3.0
182.81
1037.39
u/ml
0.76
26
200
14
92
1.53
0.72
1.7
1.3
—
—
—
0
0
13
84
1.56
0.72
1.6
1.2
—
—
—
0
0
23
170
1.36
0.68
1.2
1.4
25.94
25.66
u/l
0.01
18
135
51
422
1.22
0.66
1.0
1.1
—
—
—
0
0
83
720
1.17
0.65
3.2
3.0
1.07
0.77
ug/l
0.29
60
468
14
95
1.48
0.64
1.1
1.3
0.66
0.55
nmol/l
0.61
14
88
5
29
1.73
0.64
1.2
2.8
1431.60
581.93
u/ml
—
5
29
41
334
1.24
0.62
2.3
2.1
9.55
11.93
nmol/l
0.98
34
298
10
63
1.59
0.62
1.0
1.2
—
—
—
0
0
10
63
1.59
0.62
1.0
1.2
—
—
—
0
0
6
105
0.57
0.62
1.2
1.5
—
—
—
0
0
16
221
0.72
0.60
1.3
1.4
—
—
—
0
0
10
64
1.57
0.58
1.0
1.2
—
—
—
0
0
10
64
1.57
0.58
1.0
1.2
—
—
—
0
0
10
64
1.57
0.58
1.0
1.2
—
—
—
0
0
0
23
0.00
0.58
0.0
2.3
—
2.11
—
0
13
9
61
1.48
0.53
1.2
1.4
16.96
10.61
umol/l
—
9
54
22
169
1.31
0.53
5.3
3.2
21.39
24.91
mg/l
0.21
15
106
70
798
0.87
0.52
1.7
1.7
—
—
—
0
0
7
48
1.46
0.47
1.0
1.4
—
—
—
0
0
26
211
1.24
0.44
2.0
1.9
3.79
5.29
iu/l
—
9
77
5
31
1.62
0.43
1.0
1.1
—
—
—
0
0
0
16
0.00
0.41
0.0
1.1
—
318.99
—
0
11
5
36
1.39
0.38
2.2
1.7
102.20
102.33
%
—
5
36
5
36
1.39
0.38
1.8
1.2
48.06
150.46
pmol/l
—
5
36
52
458
1.14
0.38
1.3
1.4
—
—
—
0
0
26
216
1.21
0.37
1.2
1.4
301.94
303.16
ug/g
0.01
16
117
135
1260
1.08
0.35
5.0
4.9
2.14
2.59
ug/l
0.58
115
1121
6
42
1.43
0.35
1.5
1.3
5.80
5.85
mmol/l
—
6
42
9
125
0.72
0.35
1.4
1.5
—
—
—
0
0
36
415
0.86
0.35
1.3
1.6
—
—
—
0
0
12
154
0.78
0.32
1.1
1.0
0.36
1.80
u/ml
—
6
73
37
323
1.15
0.32
1.4
1.6
221.97
310.60
mu/l
2.97
29
294
32
365
0.87
0.28
1.4
1.5
—
—
—
0
0
109
1021
1.08
0.28
4.0
4.3
22.67
21.65
%
0.27
51
475
9
118
0.76
0.27
1.1
1.1
—
—
—
0
0
11
87
1.27
0.24
2.4
2.2
105.36
105.85
mmol/l
0.14
11
87
11
87
1.27
0.24
2.4
2.2
4.06
4.02
mmol/l
0.14
11
87
5
40
1.25
0.22
1.8
2.2
—
—
—
0
0
0
11
0.00
0.21
0.0
1.1
—
—
—
0
0
0
10
0.00
0.21
0.0
1.4
—
—
—
0
0
8
105
0.76
0.21
1.1
1.3
—
—
—
0
0
0
14
0.00
0.20
0.0
1.5
—
8.09
—
0
9
6
49
1.23
0.20
1.0
1.1
—
—
—
0
0
16
137
1.17
0.19
1.1
1.1
—
—
—
0
0
10
81
1.24
0.18
1.6
2.3
5.48
5.23
umol/l
—
5
53
203
1973
1.04
0.16
1.9
1.6
1.55
1.34
mmol/l
1.42
171
1673
51
542
0.94
0.14
1.5
1.7
—
—
—
0
0
34
316
1.08
0.12
1.5
1.9
490.44
3206.69
u/l
—
8
119
21
231
0.91
0.12
2.1
1.4
266.03
145.17
pmol/l
0.45
21
225
32
342
0.93
0.11
1.5
1.7
5.76
3.47
mg/l
0.38
25
252
16
177
0.90
0.10
1.1
1.1
0.75
1.82
u/ml
—
9
89
12
134
0.89
0.08
1.7
1.7
24.92
42.96
nmol/l
4.64
12
127
6
57
1.05
0.08
1.0
1.1
—
—
—
0
0
6
58
1.03
0.08
1.0
1.5
0.92
1.02
g/l
—
6
58
15
137
1.10
0.07
1.3
1.1
6.02
2.39
u/ml
—
6
62
8
90
0.89
0.06
1.0
1.1
—
—
—
0
0
8
90
0.89
0.06
1.4
1.9
143.75
210.78
pmol/l
—
8
83
161
1622
0.99
0.02
1.6
1.5
—
—
—
0
0
19
198
0.96
0.02
1.6
1.3
—
—
—
0
0
11
117
0.94
0.01
1.2
1.2
2.17
3.66
u/ml
—
6
35
25
251
1.00
0.00
1.2
1.4
—
—
—
0
0
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
63.67
—
0
6
0
6
0.00
0.00
0.0
1.0
—
8.05
—
0
6
0
8
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
6
64
0.94
-0.00
1.0
1.0
292.83
231.70
mg/l
—
6
56
5
50
1.00
-0.00
1.8
1.3
70.00
72.64
umol/l
—
5
50
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
12.80
—
0
5
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint N14_RENALTUBULOOTH and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| N14_RENALTUBULOOTH | 2.213 [1.69, 2.9] | < 0.001 |
| Birth year | 0.998 [0.99, 1.01] | 0.631 |
During the follow-up period (1.1.1998 — 31.12.2019), 243 out of 782 females with N14_RENALTUBULOOTH died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| N14_RENALTUBULOOTH | 2.768 [2.02, 3.79] | < 0.001 |
| Birth year | 0.987 [0.98, 1.0] | 0.006 |
During the follow-up period (1.1.1998 — 31.12.2019), 196 out of 576 males with N14_RENALTUBULOOTH died.
Mortality risk
Mortality risk for people of age
years, who have N14_RENALTUBULOOTH.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.2% | 0.509% |
| 5 | 1.23% | 3.245% |
| 10 | 3.341% | 7.871% |
| 15 | 6.65% | 14.263% |
| 20 | 11.615% | 22.939% |
Relationships between endpoints
↥Index endpoint: N14_RENALTUBULOOTH – Other renal tubulo-interstitial diseases
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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