kidney disease: A disease involving the kidney.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleNone |
520210 |
2. Check conditionsNone |
520210 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
918 |
4. Check minimum number of eventsNone |
918 |
5. Include endpointsNone |
918 |
6. Filter based on genotype QC (FinnGen only) |
918 |
Control definitions (FinnGen only)
- Control exclude
- N14_RENALTUB
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- N10-N16
- Name in latin
- Aliae nephropathiae tubulo-interstitiales
Similar endpoints
↥List of similar endpoints to
Other renal tubulo-interstitial diseases
based on the number of shared cases.
Similar with more cases:
- Renal tubulo-interstitial diseases
- Genitourinary diseases
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 9679 | 7187 | 2383 |
| Only index persons | 6588 | 5004 | 1584 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.17 | 0.21 | 0.07 |
| Only index persons | 0.15 | 0.18 | 0.06 |
| Median age at first event (years) | |||
| Whole population | 38.03 | 34.69 | 47.32 |
| Only index persons | 22.72 | 20.14 | 30.86 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 918 | 695 | 223 |
| Unadjusted period prevalence (%) | 0.20 | 0.24 | 0.10 |
| Median age at first event (years) | 27.25 | 20.14 | 49.41 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
No data
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 841
- Matched controls
- 8410
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
59099
ICD-8 Finland
Infections of kidney, Other
+∞
323.0
349
*
59098
ICD-8 Finland
Infections of kidney, Alia definita
+∞
199.1
183
*
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
43.2
162.1
202
61
N15.1
ICD-10 Finland
Renal and perinephric abscess
+∞
126.3
118
*
204
Kela drug reimbursment
Leukemia lymphatica
19.8
118.0
184
117
N15.9
ICD-10 Finland
Renal tubulo-interstitial disease, unspecified
+∞
100.0
94
*
N18.9
ICD-10 Finland
Chronic kidney disease, unspecified
49.7
77.1
93
21
138
Kela drug reimbursment
Severe anaemia associated with chronic renal failure
389.5
72.9
72
*
123
Kela drug reimbursment
Chronic disorders of vitamin D metabolism
193.5
69.2
71
*
N18.8
ICD-10 Finland
Other chronic renal failure
140.7
61.8
65
5
59010
ICD-8 Finland
Infections of kidney, Pyelonephritis
+∞
60.1
57
*
Z94.0
ICD-10 Finland
Kidney transplant status
551.1
53.1
52
*
127
Kela drug reimbursment
Transplant complication
74.7
49.7
56
8
N17.9
ICD-10 Finland
Acute renal failure, unspecified
+∞
49.5
47
*
A11CC03
ATC
alfacalcidol; systemic
51.7
48.6
58
12
TK800
NOMESCO Finland
Hemodialysis
58.7
47.1
55
10
I15.1
ICD-10 Finland
Hypertension secondary to other renal disorders
483.4
46.8
46
*
Z49.1
ICD-10 Finland
Extracorporeal dialysis
483.4
46.8
46
*
KH1AE
NOMESCO Finland
Urinary tract ultrasound examination
12.3
46.4
86
77
A12AA04
ATC
calcium carbonate; oral
106.2
46.3
50
5
N18.0
ICD-10 Finland
End-stage renal disease
+∞
44.1
42
*
KAS10
NOMESCO Finland
Allogenic transplantation of kidney from cadaver donor
+∞
43.1
41
*
L04AA06
ATC
mycophenolic acid; systemic
32.6
41.9
55
18
J01MA02
ATC
ciprofloxacin; systemic
2.8
40.8
383
1944
137
Kela drug reimbursment
Uraemia requiring dialysis
+∞
39.9
38
*
PBL10
NOMESCO Finland
Construction of arteriovenous fistula from radial artery
394.5
38.4
38
*
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
4.1
37.3
161
458
Z49.0
ICD-10 Finland
Preparatory care for dialysis
350.7
34.2
34
*
N15.8
ICD-10 Finland
Other specified renal tubulo-interstitial diseases
+∞
33.6
32
*
KA1AE
NOMESCO Finland
Kidney ultrasound examination
17.1
33.3
53
33
B05DA
ATC
Isotonic solutions
+∞
32.5
31
*
190
Kela drug reimbursment
Lanthanum carbonate, sevelamer and sucroferric oxyhydroxide
+∞
32.5
31
*
N13.3
ICD-10 Finland
Other and unspecified hydronephrosis
324.4
31.0
31
*
B03XA02
ATC
darbepoetin alfa; parenteral
29.9
30.1
40
14
5909X
ICD-9 Finland
Infections of kidney, Infection of kidney, unspecified
+∞
29.3
28
*
5901A
ICD-9 Finland
Infections of kidney, Acute pyelonephritis
+∞
28.3
27
*
KA2AE
NOMESCO Finland
Ultrasound examination transplanted kidney
+∞
28.3
27
*
J01EA01
ATC
trimethoprim; systemic
2.5
27.6
279
1400
B05DB
ATC
Hypertonic solutions
+∞
27.2
26
*
KA2AT
NOMESCO Finland
Biopsy of transplanted kidney with ultrasound guidance
+∞
27.2
26
*
L04AD02
ATC
tacrolimus; systemic (calcineurin inhibitors)
144.6
26.8
28
*
Y0699
ICD-8 Finland
Examination of the urinary and genital organs, Urinary organs. Does not include urine tests to determine endocrine and metabolic disorders (Y 00.99)
35.4
26.7
34
10
C03CA01
ATC
furosemide; systemic
2.6
26.4
242
1146
V03AE01
ATC
polystyrene sulfonate; oral
38.1
26.3
33
9
59000
ICD-8 Finland
Infections of kidney, Pyelonephritis chronica
+∞
26.2
25
*
KA3AT
NOMESCO Finland
Biopsy of kidney with ultrasound guidance
36.9
25.4
32
9
Z49.2
ICD-10 Finland
Other dialysis
+∞
25.1
24
*
N19
ICD-10 Finland
Unspecified kidney failure
20.8
24.5
36
18
59358
ICD-8 Finland
Other diseases of kidney and ureter, Morbi ureteris alii
+∞
24.1
23
*
V03AE02
ATC
sevelamer; oral
+∞
24.1
23
*
L04AD01
ATC
ciclosporin; systemic
13.9
23.4
40
30
B03XA01
ATC
erythropoietin; parenteral
37.5
23.1
29
8
N25.8
ICD-10 Finland
Other disorders resulting from impaired renal tubular function
+∞
23.0
22
*
KH1BT
NOMESCO Finland
Urinary tract cathetrisation with X-ray guidance
85.9
22.8
25
*
5902A
ICD-9 Finland
Infections of kidney, Renal and perinephric abscess
+∞
22.0
21
*
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
5.1
21.8
71
150
N39.0
ICD-10 Finland
Urinary tract infection, site not specified
2.8
20.6
143
565
TPH90
NOMESCO Finland
Removal of fixed intravenous catheter
17.8
20.1
31
18
A49.9
ICD-10 Finland
Bacterial infection, unspecified
3.6
20.1
97
297
J01CA08
ATC
pivmecillinam; oral
2.0
20.1
411
2731
A41.8
ICD-10 Finland
Other specified sepsis
21.4
20.0
29
14
320
Kela drug reimbursment
Lanthanum carbonate, sevelamer and sucroferric oxyhydroxide
+∞
19.9
19
*
A41.5
ICD-10 Finland
Sepsis due to other Gram-negative organisms
11.3
19.8
37
34
Q61.2
ICD-10 Finland
Polycystic kidney, autosomal dominant
75.3
19.8
22
*
J01MA12
ATC
levofloxacin; systemic
2.5
19.4
170
768
R50.9
ICD-10 Finland
Fever, unspecified
2.8
19.3
134
530
196
Kela drug reimbursment
Paricalcitol and cinacalcet
+∞
18.8
18
*
TJA35
NOMESCO Finland
Removal of peritoneal dialysis catheter
+∞
18.8
18
*
N12
ICD-10 Finland
Tubulo-interstitial nephritis, not specified as acute or chronic
28.6
18.8
25
9
N11.9
ICD-10 Finland
Chronic tubulo-interstitial nephritis, unspecified
+∞
17.8
17
*
JAK10
NOMESCO Finland
Laparotomy and insertion of peritoneal dialysis catheter
+∞
17.8
17
*
J01MA06
ATC
norfloxacin; oral
2.5
17.6
150
666
205
Kela drug reimbursment
Chronic hypertension
2.2
17.4
200
1031
TK820
NOMESCO Finland
Peritoneal dialysis
+∞
16.7
16
*
B03XA03
ATC
methoxy polyethylene glycol-epoetin beta; parenteral
+∞
16.7
16
*
59020
ICD-8 Finland
Infections of kidney, Abscess of kidney and perirenal tissue
+∞
16.7
16
*
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.9
16.3
325
2086
L04AA01
ATC
[U] ciclosporin; systemic
10.0
16.3
32
33
PG1DE
NOMESCO Finland
Other extensive ultrasound examination of artery
4.8
16.0
53
115
PBL09
NOMESCO Finland
Construction of arteriovenous fistula from brachial artery
+∞
15.7
15
*
TK810
NOMESCO Finland
Hemofiltration
+∞
15.7
15
*
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
2.7
15.6
116
475
UKC02
NOMESCO Finland
Cystoscopy
2.6
15.6
118
488
TPX10
NOMESCO Finland
Implantation of vascular injection port
6.8
15.2
38
58
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
2.3
15.0
157
770
A41.0
ICD-10 Finland
Sepsis due to Staphylococcus aureus
10.7
14.8
28
27
N30.0
ICD-10 Finland
Acute cystitis
2.4
14.5
131
597
R31
ICD-10 Finland
Unspecified haematuria
3.0
13.7
82
291
Q61.3
ICD-10 Finland
Polycystic kidney, unspecified
+∞
13.6
13
*
N18.5
ICD-10 Finland
Chronic kidney disease, stage 5
+∞
13.6
13
*
A10AC01
ATC
insulin (human); parenteral (insulins and analog. for injection, intermediate-acting)
3.1
13.5
76
260
N03.9
ICD-10 Finland
Chronic nephritic syndrome, unspecified
142.2
13.5
14
*
KH1FT
NOMESCO Finland
Exchange of urinary catheter with radiological guidance
142.2
13.5
14
*
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
2.5
13.4
111
480
N02AX02
ATC
tramadol; systemic, rectal
1.8
13.4
340
2326
H05BX01
ATC
cinacalcet; oral
40.8
13.2
16
*
J01DB01
ATC
cefalexin; oral
1.9
13.0
669
5669
M04AA01
ATC
allopurinol; systemic
2.8
12.8
84
319
G04AB05
ATC
NA
5.0
12.8
41
86
N08.2*D89.80
ICD-10 Finland
Immunoglobulin A (IgA) nephropathy
32.6
12.6
16
5
N11.8
ICD-10 Finland
Other chronic tubulo-interstitial nephritis
+∞
12.5
12
*
NK6QA
NOMESCO Finland
Measurement of bone density from tow or more locations with X-ray
3.4
12.5
62
195
KBV02
NOMESCO Finland
Cystoscopic insertion of stent into ureter
7.8
12.5
28
37
A06AD11
ATC
lactulose; oral
2.3
12.4
120
562
TKC20
NOMESCO Finland
Catheterisation of bladder
3.4
12.2
60
187
A10AB05
ATC
insulin aspart; parenteral (insulins and analog. for injection, fast-acting)
3.3
12.2
62
199
J01EE01
ATC
sulfamethoxazole and trimethoprim; systemic
3.3
12.1
61
194
1530
FHL
Urethrocystoscopy
7.7
12.0
27
36
N28.9
ICD-10 Finland
Disorder of kidney and ureter, unspecified
47.4
11.9
14
*
JN3AD
NOMESCO Finland
Abdominal CT examination
3.1
11.9
65
220
L04AX01
ATC
azathioprine; systemic
3.7
11.7
50
140
H02AB04
ATC
methylprednisolone; systemic
2.2
11.6
129
648
A41.9
ICD-10 Finland
Sepsis, unspecified
5.6
11.6
33
61
TPH04
NOMESCO Finland
Cathetrisation of vein
2.0
11.6
163
899
A12AA12
ATC
[U] calcium acetate anhydrous; systemic
+∞
11.5
11
*
N13.9
ICD-10 Finland
Obstructive and reflux uropathy, unspecified
+∞
11.5
11
*
V03AE03
ATC
lanthanum carbonate; oral
+∞
11.5
11
*
C08CA01
ATC
amlodipine; oral
1.8
11.2
233
1478
A10AE04
ATC
insulin glargine; parenteral
2.8
11.0
72
273
25000
ICD-8 Finland
Diabetes mellitus, Sine complicatione
5.4
11.0
32
61
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
2.5
10.8
84
351
59902
ICD-8 Finland
Other diseases of urinary tract, Infectiones tractuum urinariorum NUD
10.8
10.8
20
19
321
Kela drug reimbursment
Paricalcitol and cinacalcet
28.4
10.7
14
5
A10AB01
ATC
insulin (human); parenteral (insulins and analog. for injection, fast-acting)
4.3
10.7
39
95
R33
ICD-10 Finland
Retention of urine
3.3
10.6
52
163
75348
ICD-8 Finland
Congenital anomalies of urinary system, Maleformationes ureteris aliae
111.3
10.4
11
*
PG5RT
NOMESCO Finland
PTA of arterio-venous shunt for dialysis
+∞
10.4
10
*
N13.0
ICD-10 Finland
Hydronephrosis with ureteropelvic junction obstruction
+∞
10.4
10
*
SPAT1262
SPAT
Handing over of treatment supplies
2.0
10.4
136
727
TPH07
NOMESCO Finland
Cathetrisation of artery
2.6
10.3
78
321
QDB10
NOMESCO Finland
Major dressing of wound of skin of lower limb
3.6
10.3
46
134
N08.39*E11.2
ICD-10 Finland
Non-insulin-dependent diabetes mellitus - Diabetic nephropathy
19.1
10.3
15
8
H02AB06
ATC
prednisolone; systemic
1.6
10.1
365
2699
I10
ICD-10 Finland
Essential (primary) hypertension
1.6
10.0
376
2812
E10.7
ICD-10 Finland
Type 1 diabetes mellitus, With multiple complications
5.3
9.9
29
56
N20.0
ICD-10 Finland
Calculus of kidney
6.1
9.9
26
44
KBV12
NOMESCO Finland
Transluminal endoscopic removal of stent from ureter
12.4
9.9
17
14
C09AA02
ATC
enalapril; systemic
2.0
9.8
143
799
E11.9
ICD-10 Finland
Type 2 diabetes mellitus, without complications
1.9
9.7
148
840
WX882
NOMESCO Finland
High dependency care
5.4
9.7
28
53
J01MA01
ATC
ofloxacin; systemic
2.6
9.7
74
306
G04AC01
ATC
NA
3.7
9.6
41
115
WX408
NOMESCO Finland
General anesthesy, balanced
1.7
9.5
211
1357
KH1AD
NOMESCO Finland
CT of urinary organs
4.4
9.5
33
77
N08.39*E10.2
ICD-10 Finland
Insulin-dependent diabetes mellitus - Diabetic nephropathy
30.4
9.4
12
*
58209
ICD-8 Finland
Chronic nephritis, Unspecified
30.4
9.4
12
*
XPX99
NOMESCO Finland
Other diagnostic examination of periferal vessel
3.1
9.4
50
167
Z99.2
ICD-10 Finland
Dependence on renal dialysis
+∞
9.4
9
*
N17.0
ICD-10 Finland
Acute renal failure with tubular necrosis
+∞
9.4
9
*
TJA33
NOMESCO Finland
Percutaneous introduction of peritoneal dialysis catheter
+∞
9.4
9
*
E10.1
ICD-10 Finland
Type 1 diabetes mellitus, With ketoacidosis
12.5
9.4
16
13
N30.9
ICD-10 Finland
Cystitis, unspecified
3.1
9.3
50
168
WX892
NOMESCO Finland
Monitored bed care
2.9
9.3
56
203
C08CA02
ATC
felodipine; oral
2.5
9.3
70
291
E11.7
ICD-10 Finland
Type 2 diabetes mellitus, with multiple complications
3.8
9.2
38
104
J18.9
ICD-10 Finland
Pneumonia, unspecified
1.8
9.2
164
982
A10AA01
ATC
NA
4.4
9.2
32
75
J01FF01
ATC
clindamycin; systemic
1.7
9.1
209
1356
103
Kela drug reimbursment
Diabetes, insulin-treated
1.8
9.1
175
1073
E10.2
ICD-10 Finland
Type 1 diabetes mellitus, With renal complications
15.8
9.1
14
9
SPAT1255
SPAT
Intravenous administration of medicine
2.9
9.0
52
184
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
1.7
8.9
246
1680
H3603, E103
ICD-10 Finland
NA
12.7
8.9
15
12
C07AB07
ATC
bisoprolol; oral
1.6
8.8
312
2273
KA3EB
NOMESCO Finland
Antegrade pyelography
50.5
8.7
10
*
J01DA01
ATC
[U] cefalexin; systemic
1.5
8.6
516
4256
G04AA01
ATC
NA
9.1
8.6
17
19
C02AC05
ATC
moxonidine; oral
3.8
8.5
34
91
A10AA02
ATC
NA
3.6
8.5
37
107
E11.8
ICD-10 Finland
Type 2 diabetes mellitus, with unspecified complications
2.6
8.4
61
247
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.7
8.4
212
1412
Q61.5
ICD-10 Finland
Medullary cystic kidney
+∞
8.3
8
*
KA9AE
NOMESCO Finland
Ultrasound examination transplanted kidney
+∞
8.3
8
*
B25.8
ICD-10 Finland
Other cytomegaloviral diseases
+∞
8.3
8
*
N17.8
ICD-10 Finland
Other acute renal failure
+∞
8.3
8
*
59012
ICD-8 Finland
Infections of kidney, Pyelocystitis
+∞
8.3
8
*
U14
ICPC
Kidney symptom/complaint
8.6
8.3
17
20
A10AB04
ATC
insulin lispro; parenteral (insulins and analog. for injection, fast-acting)
3.8
8.3
34
93
R11
ICD-10 Finland
Nausea and vomiting
2.4
8.3
67
289
215
Kela drug reimbursment
Diabetes, non-insulin-treated
1.8
8.3
153
925
M10.9
ICD-10 Finland
Gout, unspecified
3.3
8.2
40
126
JN3BD
NOMESCO Finland
Extensive abdominal CT
2.2
8.2
86
420
C08CA13
ATC
lercanidipine; oral
2.2
8.1
86
422
A02BC01
ATC
omeprazole; systemic
1.7
8.1
207
1378
J01EE02
ATC
sulfadiazine and trimethoprim; systemic
1.7
8.1
211
1410
C07AB02
ATC
metoprolol; systemic
1.8
8.1
148
888
00920
ICD-8 Finland
Diarrhoeal disease, Gastroenteritis (acuta) (infectiosa)
3.7
7.9
33
92
AA1AD
NOMESCO Finland
CT of head and brain
1.7
7.9
164
1028
E87.5
ICD-10 Finland
Hyperkalaemia
8.6
7.8
16
19
WYA30
NOMESCO Finland
Preparations for expected poor cooperation
2.3
7.8
71
323
U70
ICPC
Pyelonephritis/pyelitis
10.9
7.8
14
13
UKB02
NOMESCO Finland
Retrograde ureteroscopy
9.5
7.8
15
16
A28
ICPC
Limited function/disability NOS
2.0
7.8
105
567
I15.0
ICD-10 Finland
Renovascular hypertension
45.4
7.7
9
*
N02AJ06
ATC
codeine and paracetamol; systemic
1.6
7.6
278
2022
KA1MN
NOMESCO Finland
Glomerular filtration rate (GFR) Isotope mesurement
25.3
7.6
10
*
K65.0
ICD-10 Finland
Acute peritonitis
9.0
7.6
15
17
J01XE01
ATC
nitrofurantoin; oral
4.6
7.4
24
53
XCK10
NOMESCO Finland
Photography of fundus of eye
2.2
7.4
71
334
PBU84
NOMESCO Finland
Plastic repair of arteriovenous fistula from artery of upper extremity
+∞
7.3
7
*
7151
FHL
Kidney transplantation
+∞
7.3
7
*
T86.1
ICD-10 Finland
Kidney transplant failure and rejection
+∞
7.3
7
*
N15.0
ICD-10 Finland
Balkan nephropathy
+∞
7.3
7
*
PBM10
NOMESCO Finland
Closure of arteriovenous fistula of radial artery
+∞
7.3
7
*
5937A
ICD-9 Finland
Other disorders of kidney and ureter, Vesicoureteric reflux
+∞
7.3
7
*
N05BA04
ATC
oxazepam; oral
1.6
7.2
195
1313
A41.1
ICD-10 Finland
Sepsis due to other specified staphylococcus
30.3
7.2
9
*
E10.8
ICD-10 Finland
Type 1 diabetes mellitus, With unspecified complications
6.6
7.1
17
26
WX204
NOMESCO Finland
Axillary plexus blockaced
3.6
7.0
30
86
E10.9
ICD-10 Finland
Type 1 diabetes mellitus, Without complications
2.9
7.0
40
141
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
2.3
7.0
63
287
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
2.0
7.0
90
481
L97
ICD-10 Finland
Ulcer of lower limb, not elsewhere classified
3.8
6.9
27
72
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
2.1
6.9
75
373
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.5
6.8
296
2228
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
1.8
6.8
109
629
ZXA00
NOMESCO Finland
Right side
1.6
6.8
188
1273
JA3BT
NOMESCO Finland
Cathetrisation of abdominal cavity with X-ray guidance
40.4
6.8
8
*
L89
ICD-10 Finland
Decubitus ulcer and pressure area
7.3
6.7
15
21
E11.2
ICD-10 Finland
Type 2 diabetes mellitus, with renal complications
4.5
6.7
22
50
N20.1
ICD-10 Finland
Calculus of ureter
3.3
6.7
32
101
30660
ICD-8 Finland
Special symptoms not elsewhere classified, Enuresis
22.7
6.7
9
*
KAC00
NOMESCO Finland
Nephrectomy
22.7
6.7
9
*
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
1.7
6.7
134
828
TPH20
NOMESCO Finland
Insertion of central venous catheter through subclavian or brachiocephalic vein
4.3
6.6
23
55
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.5
6.6
283
2121
E10.3
ICD-10 Finland
Type 1 diabetes mellitus, With ophthalmic complications
3.8
6.6
26
70
A02BC02
ATC
pantoprazole; systemic
1.5
6.6
486
4074
E10
ICD-10 Finland
Type 1 diabetes mellitus
4.9
6.6
20
42
EBA15
NOMESCO Finland
Extraction of large number of teeth
3.3
6.5
30
92
SPAT1263
SPAT
Sampling
1.5
6.5
312
2401
N08.2
ICD-10 Finland
Glomerular disorders in blood diseases and disorders involving the immune mechanism
70.4
6.4
7
*
Q61.0
ICD-10 Finland
Congenital single renal cyst
70.4
6.4
7
*
N28.1
ICD-10 Finland
Cyst of kidney
5.6
6.3
17
31
WX002
NOMESCO Finland
Sedation and analgesia
1.7
6.3
137
866
KC1EE
NOMESCO Finland
Ultrasound measurement of residual urine
2.2
6.3
64
310
A46
ICD-10 Finland
Erysipelas
1.9
6.3
88
481
T89
ICPC
Diabetes insulin dependent
3.2
6.3
30
95
KA5AT
NOMESCO Finland
Puncture of kidney cyst with ultrasound guidance
+∞
6.3
6
*
59199
ICD-8 Finland
Hydronephrosis
+∞
6.3
6
*
N13.1
ICD-10 Finland
Hydronephrosis with ureteral stricture, not elsewhere classified
+∞
6.3
6
*
N06AX21
ATC
duloxetine; oral
1.9
6.3
88
484
J44.0
ICD-10 Finland
Chronic obstructive pulmonary disease with acute lower respiratory infection
3.6
6.2
26
74
XF400
NOMESCO Finland
ECG with 12 standard connections
1.8
6.2
114
684
I50.9
ICD-10 Finland
Heart failure, unspecified
2.0
6.2
78
411
212
Kela drug reimbursment
Gout
5.1
6.2
18
36
N05BA01
ATC
diazepam; systemic, rectal
1.8
6.2
100
578
ZX120
NOMESCO Finland
Intravenous
2.1
6.1
69
348
XKD00
NOMESCO Finland
Uroflowmetry
2.0
6.1
77
405
N18
ICD-10 Finland
Chronic kidney disease
12.6
6.1
10
8
Z01.0
ICD-10 Finland
Examination of eyes and vision
1.7
6.1
121
748
H26.3
ICD-10 Finland
Drug-induced cataract
10.1
6.0
11
11
D41.0
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Kidney
4.2
6.0
21
51
N05CD07
ATC
temazepam; oral
1.9
6.0
86
474
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
232
696
4.12
68.83
16.7
3.0
1.1
1.0
mmol/l
3.44
221
642
160
435
4.24
53.42
9.4
2.3
126.6
64.4
ng/l
6.61
143
388
86
135
6.92
53.29
6.1
3.1
1.9
1.1
mg/l
8.04
81
128
107
223
5.30
49.44
9.6
2.2
23.3
24.4
mmol/l
2.99
97
195
155
469
3.77
44.14
8.8
2.4
0.8
2.2
mmol/l
4.40
128
365
216
874
2.92
37.82
6.0
1.8
2.2
2.4
g/l
6.58
210
808
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
68
120
6.04
37.39
3.6
2.7
0.3
0.4
u/ml
1.39
33
60
203
803
2.96
36.97
6.1
1.8
22.2
23.3
%
0.59
188
688
59
97
6.43
34.79
8.6
5.1
3209.7
133.4
iu/ml
—
15
10
224
980
2.70
33.40
6.0
1.8
11.9
13.7
umol/l
3.72
219
899
55
95
6.09
30.86
2.2
1.3
123.7
117.9
u/ml
—
7
18
318
1743
2.26
28.27
5.9
2.5
0.2
0.4
e6/l
1.70
260
1284
495
3302
2.08
25.84
16.3
4.9
1.2
1.2
mmol/l
0.18
416
2767
117
413
3.10
25.54
1.5
1.5
—
—
—
0
0
255
1326
2.28
25.30
4.7
2.1
4.1
7.3
e6/l
4.09
227
1160
65
159
4.32
24.48
1.5
1.4
—
—
—
0
0
201
957
2.41
24.35
2.6
1.8
29.9
29.4
s
0.59
196
930
29
32
9.32
23.94
1.5
1.3
—
—
—
0
0
437
2845
2.02
23.73
9.0
3.8
34.5
36.2
g/l
6.79
412
2643
73
201
3.86
23.43
3.2
1.8
1.6
1.3
g/l
1.56
67
173
326
1917
2.09
23.36
5.4
2.8
6.8
7.6
mmol/l
2.31
285
1599
206
1010
2.34
23.25
4.6
2.8
0.8
0.8
mmol/l
0.28
195
942
317
1849
2.09
23.18
5.9
3.5
29.1
6.3
mg/mmol
3.04
232
1122
197
950
2.37
23.08
2.2
1.7
—
—
—
0
0
95
319
3.21
22.49
5.9
2.6
1.0
2.1
mmol/l
1.87
70
240
194
945
2.33
22.13
4.8
2.2
5.1
3.1
e6/l
0.68
118
480
294
1699
2.07
21.81
2.5
2.0
3.2
3.1
mg/l
0.38
256
1432
52
117
4.65
21.74
1.7
1.1
223.9
242.7
u/ml
0.17
40
64
98
342
3.09
21.73
5.8
2.6
5.1
5.2
kpa
1.09
92
315
617
4646
2.00
20.94
7.7
3.7
201.7
1149.9
e6/l
—
7
64
438
2959
1.92
20.37
14.8
4.5
1.2
1.2
mmol/l
1.16
404
2673
140
610
2.53
20.32
4.2
4.0
269.8
244.6
u/l
0.41
135
568
52
127
4.28
19.61
1.6
1.1
—
—
—
0
0
199
1029
2.19
19.44
4.5
2.2
1.8
1.0
e6/l
0.44
120
558
16
10
16.26
18.54
1.1
1.1
—
—
—
0
0
470
3353
1.82
17.48
4.7
2.6
151.8
94.1
ug/l
5.89
448
3103
274
1660
1.93
17.07
3.7
2.2
3031.9
6498.7
umol/l
0.86
247
1435
16
0
+∞
16.71
12.5
0.0
5.1
—
mmol/l
—
16
0
137
652
2.29
16.18
2.0
1.6
—
—
—
0
0
473
3456
1.76
15.57
6.1
3.2
0.0
0.0
estimate
0.00
99
647
326
2143
1.81
15.39
3.5
2.2
56.5
56.9
u/l
0.04
305
1976
142
701
2.21
15.32
10.1
5.9
103.5
104.5
mmol/l
1.43
137
684
478
3515
1.75
15.27
6.2
3.2
0.0
0.0
estimate
0.80
97
638
474
3481
1.75
15.18
7.9
4.4
0.0
0.0
estimate
0.50
102
654
135
658
2.23
15.01
2.0
1.7
—
—
—
0
0
40
101
4.09
14.45
1.6
1.3
—
—
—
0
0
40
101
4.09
14.45
1.6
1.3
—
—
—
0
0
424
3050
1.72
14.36
3.3
2.2
73.6
76.8
nmol/l
1.65
384
2757
481
3587
1.72
14.24
7.5
5.4
9.5
10.7
umol/l
2.36
463
3388
384
2727
1.70
13.35
2.2
1.9
94.6
97.4
pmol/l
0.53
205
1382
196
1146
1.90
13.17
2.1
1.7
1221.9
1181.1
nmol/l
0.19
151
851
101
460
2.34
13.13
2.6
2.3
65.9
67.2
g/l
0.77
95
420
80
334
2.53
12.56
6.7
2.5
117.8
127.3
g/l
2.99
80
328
107
512
2.23
12.37
2.3
2.5
10.7
10.5
g/l
0.19
101
472
45
138
3.38
12.32
2.2
3.4
86.3
33.5
mg/l
0.97
32
113
45
138
3.38
12.32
2.2
3.4
34.7
28.2
mg/l
0.57
32
114
504
3895
1.65
12.31
7.8
3.9
7.2
6.5
mmol/l
3.51
476
3630
78
326
2.52
12.22
1.9
1.6
—
—
—
0
0
358
2553
1.66
11.89
4.0
3.2
32.1
50.5
ng/l
0.59
232
1577
333
2336
1.67
11.75
5.0
3.0
2.3
2.4
mmol/l
1.12
300
2077
68
271
2.63
11.74
12.0
8.9
24.0
24.7
mmol/l
0.89
60
252
529
4169
1.63
11.70
11.7
8.3
4.3
3.9
e9/l
2.62
485
3666
237
1525
1.75
11.47
1.7
1.5
20.4
21.2
nmol/l
0.36
212
1295
107
529
2.16
11.39
3.4
2.3
57.6
72.9
ml/min/173m2
2.66
57
209
55
200
2.86
11.31
2.3
1.7
2.8
2.7
ug/l
0.02
48
171
123
659
2.00
10.55
5.3
2.9
—
—
—
0
0
288
1994
1.65
10.45
2.4
2.0
133.5
198.2
u/l
1.16
274
1877
654
5515
1.65
10.32
11.7
6.4
79.9
75.8
u/l
2.02
624
5163
369
2741
1.58
9.89
5.9
3.3
—
—
—
0
0
35
106
3.39
9.80
1.4
1.6
—
—
—
0
0
29
79
3.76
9.49
1.1
1.2
—
—
—
0
0
129
729
1.90
9.44
24.0
21.3
1.4
1.3
inr
—
10
102
115
626
1.96
9.40
9.4
6.8
0.1
1.4
mmol/l
2.87
89
490
114
628
1.93
9.00
9.7
6.8
5.1
5.1
kpa
0.25
105
607
114
629
1.93
8.95
9.7
6.8
12.5
12.5
kpa
0.00
105
608
75
356
2.20
8.83
1.8
1.4
—
—
—
0
0
108
588
1.95
8.82
2.6
2.3
31.1
34.1
u/l
0.43
91
490
57
241
2.46
8.74
2.4
1.8
—
—
—
0
0
107
587
1.93
8.54
2.4
2.0
0.2
0.2
g/l
1.59
98
550
637
5445
1.55
8.46
5.3
3.8
16.2
10.8
mm/h
11.95
594
5052
263
1862
1.58
8.40
6.5
3.5
0.0
0.0
estimate
0.88
96
644
235
1621
1.60
8.38
3.2
2.1
—
—
—
0
0
37
129
2.95
8.25
5.8
2.2
38.5
102.3
ug/min
0.80
29
77
38
135
2.89
8.20
1.8
1.7
—
—
—
0
0
24
64
3.82
8.11
1.2
1.1
79.9
56.1
u/l
1.19
18
45
59
265
2.31
7.93
5.9
2.6
24.3
25.5
mmol/l
1.56
59
260
21
52
4.11
7.83
1.4
1.2
1901.8
1548.6
e6/l
0.15
14
41
35
122
2.94
7.82
2.5
1.7
122.5
130.6
g/l
1.13
24
90
52
224
2.40
7.68
2.0
1.7
—
—
—
0
0
47
194
2.50
7.61
1.8
1.2
—
—
—
0
0
211
1455
1.58
7.43
1.8
1.7
77128125.4
20114912.2
pmol/l
0.33
188
1223
7
0
+∞
7.30
4.7
0.0
—
—
—
0
0
52
230
2.34
7.26
1.6
1.7
0.2
0.2
g/l
0.24
52
222
241
1725
1.54
7.17
3.0
2.8
2817.6
1007.1
ng/l
3.65
207
1435
413
3301
1.46
7.11
4.6
3.7
—
—
—
0
0
33
119
2.84
6.96
3.7
1.8
15.6
16.1
%
0.27
19
52
110
652
1.78
6.87
2.5
1.9
388.0
374.3
nmol/l
0.31
101
599
11
17
6.54
6.78
2.0
2.2
—
—
—
0
0
11
17
6.54
6.78
2.0
2.2
—
—
—
0
0
29
99
2.99
6.74
1.2
1.2
—
—
—
0
0
51
232
2.27
6.69
1.8
1.6
0.0
0.1
iu/ml
0.44
13
38
42
177
2.44
6.54
2.6
2.7
—
—
—
0
0
216
1538
1.53
6.51
6.4
3.5
1.0
1.0
kg/l
1.65
37
213
38
153
2.55
6.51
1.3
1.2
—
—
—
0
0
18
46
3.97
6.46
1.4
1.2
10717.6
148050.7
e6/l
0.61
11
30
11
18
6.17
6.44
2.0
2.1
—
—
—
0
0
51
238
2.21
6.31
1.6
1.7
1.2
1.2
g/l
0.17
51
229
801
7391
1.66
6.08
26.7
11.1
24.3
20.3
mg/l
2.64
707
5693
21
64
3.33
5.88
2.2
1.7
—
—
—
0
0
32
125
2.62
5.84
3.9
3.3
4.2
4.3
e9/l
0.03
32
125
575
4983
1.41
5.83
3.7
2.9
47.5
42.0
u/l
0.95
553
4704
32
127
2.57
5.67
1.7
1.6
—
—
—
0
0
29
111
2.66
5.52
2.2
1.7
—
—
—
0
0
32
129
2.53
5.50
4.6
3.6
58.7
56.9
%
0.32
32
129
15
38
4.00
5.45
2.9
1.8
—
—
—
0
0
87
517
1.75
5.40
2.4
2.4
8.3
6.5
ug/l
0.38
72
447
19
58
3.32
5.32
2.3
1.8
—
—
—
0
0
15
39
3.89
5.27
1.1
1.1
—
—
—
0
0
304
2396
1.40
5.25
4.2
3.0
27.9
29.5
u/l
0.73
291
2289
14
35
4.05
5.18
1.3
1.1
22.2
14.8
u/l
0.46
14
29
34
146
2.38
5.13
2.1
1.7
—
—
—
0
0
8
6
13.43
5.08
1.4
3.0
—
—
—
0
0
18
55
3.32
5.04
6.1
2.5
—
—
—
0
0
34
149
2.33
4.92
2.1
1.7
—
—
—
0
0
14
37
3.83
4.82
1.3
1.1
63.3
75.6
u/l
0.45
14
32
24
91
2.68
4.68
1.2
1.1
—
—
—
0
0
11
25
4.44
4.57
2.7
2.8
—
—
—
0
0
89
559
1.66
4.53
11.6
3.0
1.2
1.2
mmol/l
0.96
82
475
16
49
3.31
4.48
2.1
1.7
—
—
—
0
0
16
49
3.31
4.48
2.1
1.7
—
—
—
0
0
16
49
3.31
4.48
2.1
1.7
—
—
—
0
0
11
26
4.27
4.36
2.1
1.8
—
—
—
0
0
11
26
4.27
4.36
2.1
1.8
—
—
—
0
0
11
26
4.27
4.36
2.1
1.8
—
—
—
0
0
11
26
4.27
4.36
2.1
1.8
—
—
—
0
0
21
78
2.73
4.27
2.4
2.5
28.4
24.3
mg/l
—
10
20
21
79
2.70
4.18
1.6
1.5
—
—
—
0
0
24
98
2.49
4.07
2.2
3.2
0.9
0.8
nmol/l
0.43
17
75
27
117
2.35
4.04
2.1
1.3
—
—
—
0
0
20
75
2.70
4.01
3.0
1.5
89.6
90.1
%
0.09
20
75
55
313
1.81
3.99
1.1
1.3
0.3
1.2
u/ml
—
5
28
727
6724
1.39
3.95
7.0
5.0
40.5
38.9
mmol/mol
3.84
679
6282
796
7493
1.47
3.81
29.6
12.3
139.2
139.7
mmol/l
5.71
777
7289
7
8
8.80
3.77
2.0
2.1
—
—
—
0
0
6
5
12.06
3.76
2.0
1.0
133.5
77.8
ng/l
—
6
5
23
96
2.43
3.75
1.5
1.5
—
—
—
0
0
213
1663
1.37
3.72
1.9
1.7
1.2
1.0
mg/l
0.86
164
1245
797
7516
1.46
3.66
30.3
12.3
4.0
3.9
mmol/l
5.34
776
7304
12
35
3.46
3.62
1.2
1.1
—
—
—
0
0
36
184
2.00
3.62
3.2
2.2
3.5
3.5
g/l
0.04
36
176
109
758
1.50
3.61
3.0
2.5
6.1
6.6
umol/l
0.17
92
652
161
1208
1.40
3.57
4.4
3.3
160.1
308.9
ng/l
0.84
125
855
8
13
6.20
3.50
1.8
1.3
—
—
—
0
0
6
6
10.05
3.50
2.0
1.5
—
—
—
0
0
45
253
1.82
3.43
1.4
2.1
—
—
—
0
0
17
64
2.69
3.41
8.2
3.5
—
—
—
0
0
220
1750
1.34
3.38
1.4
1.3
2.1
1.3
u/ml
0.41
54
457
118
848
1.45
3.32
4.9
3.9
31.4
32.3
%
0.44
88
585
20
83
2.44
3.32
1.5
1.5
—
—
—
0
0
18
71
2.57
3.31
1.6
1.5
—
—
—
0
0
49
288
1.74
3.24
2.6
1.8
—
—
—
0
0
32
164
1.99
3.22
1.2
1.2
—
—
—
0
0
18
72
2.53
3.22
2.9
1.7
32.8
32.7
pg
0.03
18
72
14
49
2.89
3.20
2.7
1.6
—
—
—
0
0
651
5990
1.30
3.18
4.5
4.1
14.6
14.6
pmol/l
0.35
596
5514
163
1249
1.37
3.18
3.5
2.6
2.5
2.4
mmol/l
0.83
131
1111
756
7108
1.36
3.14
4.9
4.2
6.0
5.8
mmol/l
3.41
689
6546
(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
12
39
3.10
3.09
1.3
1.1
—
—
—
0
0
740
6947
1.34
3.01
22.6
10.1
74.9
84.4
ml/min/173m2
16.10
628
5659
5
5
10.04
2.98
1.2
1.6
—
—
—
0
0
38
218
1.78
2.76
1.3
1.2
—
—
—
0
0
9
24
3.78
2.67
1.2
1.2
1560.2
1762.6
miu/ml
—
9
24
10
32
3.15
2.65
1.1
1.1
24.0
24.4
u/l
—
10
25
10
32
3.15
2.65
1.1
1.1
88.5
84.7
u/l
—
10
26
178
1423
1.31
2.61
1.3
1.3
22.6
29.6
iu/ml
0.84
58
453
69
469
1.51
2.60
2.8
2.6
231.0
168.9
ng/l
0.70
61
423
8
20
4.03
2.57
1.1
1.0
—
—
—
0
0
116
872
1.38
2.56
1.8
1.8
1.5
1.4
%
0.95
103
782
43
264
1.66
2.49
1.7
1.8
—
—
—
0
0
32
181
1.80
2.46
1.9
2.1
0.6
0.7
g/l
0.04
26
163
72
500
1.48
2.45
3.0
3.4
4.5
4.5
pmol/l
0.09
63
443
20
96
2.11
2.44
1.9
1.6
—
—
—
0
0
6
12
5.02
2.40
1.0
1.2
—
—
—
0
0
6
12
5.02
2.40
1.2
1.2
—
—
—
0
0
5
8
6.28
2.37
2.4
2.1
—
—
—
0
0
6
13
4.64
2.27
1.2
1.3
—
—
—
0
0
17
79
2.17
2.25
2.2
1.6
—
—
—
0
0
15
66
2.29
2.25
1.5
1.4
69.0
58.9
%
—
9
40
26
143
1.84
2.20
1.3
1.5
7599.8
17512.5
e6/l
0.91
19
107
36
220
1.66
2.15
1.2
1.3
1.9
12.7
u/ml
—
6
46
9
30
3.02
2.15
2.2
2.5
—
—
—
0
0
10
37
2.72
2.10
2.0
1.5
—
—
—
0
0
10
37
2.72
2.10
1.1
1.1
—
—
—
0
0
733
6968
1.26
2.07
5.5
4.8
1.8
2.0
mu/l
0.50
686
6448
7
20
3.52
2.05
2.1
1.7
—
—
—
0
0
818
7893
1.33
1.99
14.6
9.1
23.7
24.9
u/l
1.81
798
7645
107
833
1.32
1.91
10.1
6.0
—
—
—
0
0
763
7308
1.26
1.88
4.7
4.0
1.5
1.5
mmol/l
2.36
707
6798
778
7469
1.27
1.88
4.9
4.5
2.8
2.9
mmol/l
2.14
722
6945
5
12
4.18
1.82
1.2
1.2
—
—
—
0
0
16
80
2.02
1.80
1.3
1.4
—
—
—
0
0
7
23
3.06
1.80
1.0
1.1
—
—
—
0
0
11
47
2.36
1.78
2.5
4.6
28.8
35.6
mu/l
0.15
11
47
10
41
2.45
1.76
3.0
1.5
—
—
—
0
0
9
36
2.51
1.74
1.0
1.3
—
—
—
0
0
24
140
1.73
1.73
1.4
1.3
—
—
—
0
0
8
30
2.68
1.72
1.6
1.5
—
—
—
0
0
31
195
1.61
1.70
1.9
1.9
3.3
3.0
g/l
0.65
21
158
32
203
1.60
1.70
1.1
1.1
—
—
—
0
0
40
269
1.51
1.66
1.2
1.3
127.2
226.1
miu/ml
0.76
13
144
764
7344
1.24
1.66
4.6
4.1
4.7
4.8
mmol/l
1.98
715
6867
737
7061
1.22
1.64
4.2
3.6
1.4
1.2
mmol/l
3.07
681
6530
84
648
1.33
1.63
4.1
3.8
6.7
18.4
ug/l
0.55
69
528
5
14
3.58
1.61
1.4
1.2
—
—
—
0
0
5
14
3.58
1.61
1.2
1.1
—
—
—
0
0
12
56
2.16
1.61
1.2
1.1
—
2.8
—
0
5
32
207
1.57
1.58
1.9
1.9
—
—
—
0
0
32
207
1.57
1.58
1.9
1.9
4.1
3.6
g/l
0.94
22
154
32
207
1.57
1.58
1.9
1.9
7.0
7.3
g/l
0.54
24
162
7
26
2.70
1.58
1.4
1.3
—
—
—
0
0
7
26
2.70
1.58
1.4
1.3
—
—
—
0
0
8
33
2.44
1.54
2.3
1.5
—
—
—
0
0
11
51
2.17
1.51
1.4
1.0
—
—
—
0
0
6
21
2.87
1.50
1.0
1.2
—
—
—
0
0
78
603
1.32
1.50
1.1
1.2
107.6
141.8
iu/ml
0.50
38
251
851
8305
1.34
1.50
35.9
17.1
129.5
134.7
g/l
19.18
842
8189
16
87
1.85
1.46
1.0
1.1
5.6
5309.9
iu/ml
—
5
24
6
22
2.74
1.43
1.0
1.1
—
—
—
0
0
850
8301
1.32
1.43
35.6
17.0
4.3
4.5
e12/l
11.95
834
8084
14
74
1.91
1.39
1.2
1.0
—
—
—
0
0
14
74
1.91
1.39
1.1
1.1
—
—
—
0
0
26
166
1.58
1.38
2.1
1.9
35.3
39.0
g/l
1.19
21
148
29
193
1.52
1.30
1.2
1.3
11.2
12.8
u/l
0.20
16
149
8
34
2.36
1.29
2.3
1.5
—
—
—
0
0
8
35
2.30
1.27
1.4
1.2
—
—
—
0
0
160
1376
1.20
1.25
1.3
1.3
8.7
11.2
u/ml
0.26
55
567
655
6266
1.16
1.22
30.3
13.8
14.0
13.6
%
4.91
643
6138
5
19
2.64
1.21
1.4
1.1
—
—
—
0
0
100
824
1.24
1.20
1.6
1.9
—
—
—
0
0
22
333
0.65
1.18
1.3
1.5
—
—
—
0
0
718
6925
1.17
1.17
24.5
12.3
38.0
39.7
%
5.10
537
5243
109
910
1.22
1.16
1.6
1.9
—
—
—
0
0
10
50
2.01
1.16
1.8
1.2
—
—
—
0
0
11
196
0.56
1.13
1.3
1.4
—
—
—
0
0
14
80
1.76
1.13
1.1
1.3
—
—
—
0
0
28
192
1.47
1.12
2.0
1.9
11.7
10.0
g/l
1.31
23
169
10
51
1.97
1.11
1.0
1.2
—
—
—
0
0
10
51
1.97
1.11
1.0
1.2
—
—
—
0
0
10
51
1.97
1.11
2.3
1.6
—
—
—
0
0
7
31
2.27
1.10
1.4
1.3
—
—
—
0
0
7
31
2.27
1.10
1.4
1.3
—
—
—
0
0
5
22
2.28
1.03
1.2
1.7
—
—
—
0
0
5
22
2.28
1.03
1.2
1.7
—
—
—
0
0
5
22
2.28
1.03
1.4
1.0
41.8
30.4
u/ml
—
5
22
12
69
1.75
0.96
1.0
1.1
—
—
—
0
0
13
77
1.70
0.95
1.1
1.1
—
—
—
0
0
12
197
0.60
0.94
1.2
1.4
—
—
—
0
0
12
197
0.60
0.94
1.2
1.4
—
—
—
0
0
14
85
1.66
0.94
1.6
1.3
—
—
—
0
0
12
196
0.61
0.93
1.2
1.4
—
—
—
0
0
13
78
1.68
0.92
1.6
1.2
—
—
—
0
0
11
63
1.75
0.90
1.4
1.3
—
—
—
0
0
9
154
0.58
0.89
1.1
1.4
—
—
—
0
0
7
130
0.53
0.88
1.4
1.7
—
—
—
0
0
14
87
1.62
0.88
1.6
1.3
—
—
—
0
0
14
87
1.62
0.88
1.6
1.3
—
—
—
0
0
6
30
2.01
0.87
1.0
1.0
—
—
—
0
0
6
30
2.01
0.87
1.3
1.1
128.4
156.5
iu/ml
—
6
30
27
367
0.73
0.86
1.4
1.4
—
—
—
0
0
68
561
1.23
0.85
1.2
1.3
27.3
29.1
iu/l
0.17
52
477
141
1592
0.86
0.85
1.4
1.4
—
—
—
0
0
22
154
1.44
0.84
5.3
3.3
21.4
25.8
mg/l
0.27
15
97
31
232
1.35
0.82
1.1
1.2
—
—
—
0
0
31
233
1.34
0.80
1.1
1.2
—
—
—
0
0
7
125
0.56
0.78
1.6
1.5
—
—
—
0
0
9
53
1.70
0.75
1.1
1.4
1.7
1.5
nmol/l
—
9
45
14
91
1.55
0.75
1.1
1.3
0.7
0.6
nmol/l
0.60
14
85
9
55
1.64
0.73
1.3
1.4
—
—
—
0
0
5
25
2.01
0.72
3.6
5.4
—
—
—
0
0
13
84
1.56
0.72
1.6
1.3
—
—
—
0
0
13
84
1.56
0.72
1.6
1.3
—
—
—
0
0
23
168
1.38
0.72
1.2
1.4
25.9
24.6
u/l
0.06
18
135
13
85
1.54
0.69
1.6
1.3
—
—
—
0
0
9
59
1.53
0.68
1.2
1.5
17.0
10.7
umol/l
—
9
54
5
28
1.79
0.66
3.2
1.3
—
—
—
0
0
31
243
1.29
0.63
1.5
1.6
—
—
—
0
0
8
49
1.64
0.62
1.0
1.4
—
—
—
0
0
5
30
1.67
0.61
1.0
1.1
—
—
—
0
0
8
51
1.57
0.60
1.5
1.2
—
—
—
0
0
536
5173
1.09
0.60
3.6
3.3
—
—
—
0
0
49
409
1.21
0.60
1.0
1.1
—
—
—
0
0
15
208
0.72
0.58
1.3
1.4
—
—
—
0
0
0
23
0.00
0.58
0.0
2.3
—
2.2
—
0
13
9
61
1.48
0.53
1.0
1.2
—
—
—
0
0
9
61
1.48
0.53
1.0
1.2
—
—
—
0
0
9
62
1.46
0.53
1.0
1.2
—
—
—
0
0
9
62
1.46
0.53
1.0
1.2
—
—
—
0
0
9
62
1.46
0.53
1.0
1.2
—
—
—
0
0
6
96
0.62
0.52
1.2
1.5
—
—
—
0
0
6
40
1.50
0.51
1.5
1.3
5.8
5.9
mmol/l
—
6
40
76
671
1.14
0.50
3.2
3.0
1.1
0.8
ug/l
0.31
54
432
69
783
0.87
0.49
1.7
1.7
—
—
—
0
0
6
91
0.66
0.42
1.0
1.1
—
—
—
0
0
5
32
1.57
0.42
1.2
2.7
1431.6
599.1
u/ml
—
5
32
0
15
0.00
0.41
0.0
1.5
—
5.8
—
0
10
0
17
0.00
0.40
0.0
1.1
—
292.6
—
0
12
8
115
0.69
0.37
1.1
1.1
—
—
—
0
0
6
45
1.34
0.33
1.0
1.4
—
—
—
0
0
35
403
0.86
0.33
1.3
1.6
—
—
—
0
0
50
445
1.13
0.33
1.3
1.4
—
—
—
0
0
25
211
1.19
0.31
2.0
1.9
3.8
5.4
iu/l
—
9
77
31
358
0.86
0.31
1.4
1.5
—
—
—
0
0
35
308
1.14
0.28
2.3
2.1
9.7
11.8
nmol/l
0.75
29
272
16
131
1.23
0.27
1.1
1.1
—
—
—
0
0
123
1165
1.06
0.24
4.5
4.8
2.1
2.6
ug/l
0.70
103
1037
5
38
1.32
0.23
1.8
2.2
—
—
—
0
0
0
11
0.00
0.21
0.0
1.4
—
—
—
0
0
0
11
0.00
0.21
0.0
1.1
—
—
—
0
0
8
103
0.77
0.21
1.1
1.3
—
—
—
0
0
6
48
1.25
0.20
1.0
1.1
—
—
—
0
0
24
212
1.14
0.19
1.2
1.4
301.9
309.8
ug/g
0.08
16
115
6
53
1.13
0.18
1.0
1.1
—
—
—
0
0
195
1888
1.04
0.18
1.9
1.6
1.5
1.3
mmol/l
1.22
163
1605
99
943
1.06
0.17
3.9
4.3
22.7
21.9
%
0.17
46
432
49
526
0.93
0.17
1.5
1.7
—
—
—
0
0
34
312
1.09
0.16
1.4
1.6
219.3
311.5
mu/l
2.91
27
283
15
171
0.88
0.14
1.1
1.1
0.2
1.9
u/ml
—
7
71
20
223
0.89
0.14
2.1
1.4
277.2
146.0
pmol/l
0.47
20
217
15
134
1.12
0.11
1.3
1.1
6.0
2.4
u/ml
—
6
62
32
299
1.07
0.11
1.4
1.9
553.2
2823.5
u/l
—
7
114
6
56
1.07
0.08
1.0
1.5
0.9
1.0
g/l
—
6
56
18
193
0.93
0.06
1.6
1.2
—
—
—
0
0
32
332
0.96
0.04
1.5
1.7
5.8
3.2
mg/l
0.41
24
232
156
1571
0.99
0.02
1.6
1.5
—
—
—
0
0
12
125
0.96
0.00
1.7
1.7
24.9
43.3
nmol/l
4.70
12
120
23
234
0.98
0.00
1.2
1.4
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
8
86
0.93
0.00
1.4
2.0
143.8
211.7
pmol/l
—
8
79
0
5
0.00
0.00
0.0
1.0
—
8.1
—
0
5
5
51
0.98
0.00
1.2
1.7
7.2
7.8
mmol/l
—
5
32
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.4
—
—
—
0
0
6
60
1.00
0.00
1.0
1.1
292.8
225.2
mg/l
—
6
53
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
63.7
—
0
6
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
9
0.00
0.00
0.0
1.7
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint N14_RENALTUBULOOTH and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| N14_RENALTUBULOOTH | 2.213 [1.69, 2.9] | < 0.001 |
| Birth year | 0.998 [0.99, 1.01] | 0.631 |
During the follow-up period (1.1.1998 — 31.12.2019), 243 out of 782 females with N14_RENALTUBULOOTH died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| N14_RENALTUBULOOTH | 2.768 [2.02, 3.79] | < 0.001 |
| Birth year | 0.987 [0.98, 1.0] | 0.006 |
During the follow-up period (1.1.1998 — 31.12.2019), 196 out of 576 males with N14_RENALTUBULOOTH died.
Mortality risk
Mortality risk for people of age
years, who have N14_RENALTUBULOOTH.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.2% | 0.509% |
| 5 | 1.23% | 3.245% |
| 10 | 3.341% | 7.871% |
| 15 | 6.65% | 14.263% |
| 20 | 11.615% | 22.939% |
Relationships between endpoints
↥Index endpoint: N14_RENALTUBULOOTH – Other renal tubulo-interstitial diseases
GWS hits: 1
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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