Rare circulating lymphoid malignancy

C3_CIRCULATING_LYMPHOID

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

519972

1. Apply sex-specific rule

None

519972

2. Check conditions

None

519972

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

1 out of 7 registries used, show all original rules.

203

4. Check minimum number of events

None

203

5. Include endpoints

None

203

6. Filter based on genotype QC (FinnGen only)

197

Control definitions (FinnGen only)

Control exclude
C3_CANCER, C3_CANCER_WIDE

Extra metadata

First used in FinnGen datafreeze
DF12

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

This endpoint is excluded (different definition than used in FinnGen).

-FinnGen-

Key figures

All Female Male
Number of individuals 197 57 140
Unadjusted period prevalence (%) 0.05 0.02 0.06
Median age at first event (years) 75.49 74.11 76.05

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
203
Matched controls
2030
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
117
Kela drug reimbursment
Leukaemia and other malignant diseases of the blood and bone marrow, and malignant diseases of the lymphatic tissue
610.0
307.7
170
17
C83.1
ICD-10 Finland
Mantle cell lymphoma
+∞
140.4
118
*
XW000
NOMESCO Finland
Bone marrow biopsy
48.2
140.2
90
33
Z51.5
ICD-10 Finland
Palliative care
24.8
91.1
73
45
WW500
NOMESCO Finland
Blood transfusion
36.6
90.2
60
23
A04AA01
ATC
ondansetron; systemic, rectal
44.5
85.4
53
16
J01EE01
ATC
sulfamethoxazole and trimethoprim; systemic
20.3
76.1
66
47
M04AA01
ATC
allopurinol; systemic
12.2
74.2
127
245
L03AA02
ATC
filgrastim; parenteral
+∞
73.5
66
*
JN4BD
NOMESCO Finland
Extensive body CT
16.9
61.7
58
47
A03FA01
ATC
metoclopramide; systemic, rectal
10.9
56.5
77
108
WD125
NOMESCO Finland
Demanding cystostatic therapy of methastized malignancy
+∞
55.8
51
*
C91.0
ICD-10 Finland
Acute lymphoblastic leukaemia [ALL]
+∞
54.7
50
*
L03AA13
ATC
pegfilgrastim; parenteral
653.4
53.0
50
*
H02AB02
ATC
dexamethasone; systemic
124.6
52.9
55
6
WD405
NOMESCO Finland
Simple antiboidy therapy of methastized malignancy
+∞
47.8
44
*
A49.9
ICD-10 Finland
Bacterial infection, unspecified
8.6
47.4
81
146
WD105
NOMESCO Finland
Cystostatic therapy of methastized malignancy
552.7
46.2
44
*
TPH20
NOMESCO Finland
Insertion of central venous catheter through subclavian or brachiocephalic vein
20.9
43.9
35
20
WD415
NOMESCO Finland
Demanding antibody therapy of methastized malignancy
+∞
39.9
37
*
R50.9
ICD-10 Finland
Fever, unspecified
6.7
36.4
77
169
JN4AD
NOMESCO Finland
Body CT examination
9.6
33.3
44
57
WF049
NOMESCO Finland
Radiotherapy of metastasis
380.9
32.9
32
*
N02AA05
ATC
oxycodone; systemic
6.0
32.6
78
190
9835/3-C42.1
ICD-O-3
Precursor cell lymphoblastic leukemia, NOS, of bone marrow
+∞
31.0
29
*
D70.82
ICD-10 Finland
Drug-induced neutropenia
181.8
30.6
31
*
A04AA02
ATC
granisetron; systemic, transdermal
+∞
29.9
28
*
C83.31
ICD-10 Finland
Diffuse lymphoma with large B cells
+∞
28.8
27
*
9673/3-C42.1
ICD-O-3
Mantle cell lymphoma of bone marrow
+∞
28.8
27
*
C91.1
ICD-10 Finland
Chronic lymphocytic leukaemia of B-cell type
309.8
27.4
27
*
ZX120
NOMESCO Finland
Intravenous
7.3
25.9
43
72
390
Kela drug reimbursment
Ibrutinib
+∞
25.6
24
*
H02AB06
ATC
prednisolone; systemic
4.9
25.1
144
677
C61
ICD-10 Finland
Malignant neoplasm of prostate
+∞
24.5
23
*
WF004
NOMESCO Finland
Palliative radiotherapy
+∞
24.5
23
*
L01AA02
ATC
chlorambucil; oral
+∞
23.4
22
*
212
Kela drug reimbursment
Gout
10.6
23.2
27
29
L01BB02
ATC
mercaptopurine; oral
70.8
22.4
25
*
Z51.1
ICD-10 Finland
Chemotherapy session for neoplasm
+∞
22.3
21
*
8140/3-C61.9
ICD-O-3
Adenocarcinoma, NOS, of prostate gland
+∞
21.2
20
*
PJA10
NOMESCO Finland
Exploration of lymph nodes
85.7
21.2
23
*
J01MA12
ATC
levofloxacin; systemic
4.3
21.0
75
244
WD135
NOMESCO Finland
Demanding cystostatic therapy of methastized malignancy
+∞
20.1
19
*
1XC02, ,
NOMESCO Finland
220.6
19.9
20
*
XX3DW
NOMESCO Finland
Time consuming IT work
7.6
19.7
30
45
C90.1
ICD-10 Finland
Plasma cell leukaemia
+∞
19.1
18
*
9673/3-C77.9
ICD-O-3
Mantle cell lymphoma of lymph node, NOS
+∞
19.1
18
*
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
6.8
18.9
32
54
WZC00
NOMESCO Finland
Treatment plan or consultation
3.9
18.5
75
264
9673/3-C77.8
ICD-O-3
Mantle cell lymphoma of lymph nodes of multiple regions
+∞
18.0
17
*
R59.1
ICD-10 Finland
Generalized enlarged lymph nodes
46.6
17.7
21
5
D69.6
ICD-10 Finland
Thrombocytopenia, unspecified
17.1
17.2
27
18
ZX112
NOMESCO Finland
Subcutaneous
38.8
17.0
21
6
1512
Kela drug reimbursment
Ibrutinib
+∞
16.9
16
*
C85.9
ICD-10 Finland
Non-Hodgkin lymphoma, unspecified
+∞
15.8
15
*
WD115
NOMESCO Finland
Multiple cystostatic therapy of methastized malignancy
+∞
15.8
15
*
J05AB11
ATC
valaciclovir; oral
4.3
15.6
48
137
WZC20
NOMESCO Finland
Multidisciplinary treatment meeting
25.8
15.5
21
9
WW300
NOMESCO Finland
Transfer of autologic stem cells
+∞
14.8
14
*
8090/3-C44.9
ICD-O-3
Basal cell carcinoma, NOS, of skin, NOS
+∞
14.8
14
*
L01XE27
ATC
[U] ibrutinib
+∞
14.8
14
*
PJD41
NOMESCO Finland
Excision of cervical lymph nodes
39.2
14.7
18
5
D70.89
ICD-10 Finland
Neutropenic splenomegaly
161.1
14.7
15
*
JN6AD
NOMESCO Finland
CT of torso and neck
36.9
13.7
17
5
C92.0
ICD-10 Finland
Acute myeloblastic leukaemia [AML]
+∞
13.7
13
*
C90.0
ICD-10 Finland
Multiple myeloma
+∞
13.7
13
*
ZX090
NOMESCO Finland
Other technic of radiotherapy
149.6
13.6
14
*
ZX012
NOMESCO Finland
Radiotherapy with large shaped fields - isocentric therapy
149.6
13.6
14
*
GD1DD
NOMESCO Finland
High resolution CT examination of lungs
5.8
13.4
26
50
R59.0
ICD-10 Finland
Localized enlarged lymph nodes
13.6
13.0
22
18
NEA10
NOMESCO Finland
Exploration of soft tissue of pelvis, percutaneous
74.7
12.8
14
*
C44.31
ICD-10 Finland
Basocellular carcinoma of the skin on another or unspecified part of the face
74.7
12.8
14
*
DM1AA
NOMESCO Finland
Paranasal sinuses X-ray examination without contrast
12.8
12.7
22
19
C84.1
ICD-10 Finland
Sézary disease
+∞
12.6
12
*
C83.9
ICD-10 Finland
Non-follicular (diffuse) lymphoma, unspecified
+∞
12.6
12
*
L03AA14
ATC
lipegfilgrastim; parenteral
+∞
12.6
12
*
TAB00
NOMESCO Finland
Lumbar puncture
9.2
11.7
24
29
116
Kela drug reimbursment
Prostate cancer
+∞
11.6
11
*
PJD45
NOMESCO Finland
Excision of inguinal lymph nodes
126.9
11.5
12
*
J05AB01
ATC
aciclovir; systemic
3.1
11.1
57
225
QAE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in head or neck
11.5
11.1
20
19
127
Kela drug reimbursment
Transplant complication
29.9
10.9
14
5
N02AB03
ATC
fentanyl; nasal, sublingual, transdermal
11.0
10.8
20
20
JN6BD
NOMESCO Finland
Extensive CT of torso and neck
115.7
10.5
11
*
C95.0
ICD-10 Finland
Acute leukaemia of unspecified cell type
+∞
10.5
10
*
Z94.8
ICD-10 Finland
Other transplanted organ and tissue status
+∞
10.5
10
*
L02AE02
ATC
leuprorelin; implant, parenteral
+∞
10.5
10
*
PJ2AT
NOMESCO Finland
Biopsy of lymphnode with ultrasound guidance
+∞
10.5
10
*
C85.1
ICD-10 Finland
B-cell lymphoma, unspecified
+∞
10.5
10
*
TPH90
NOMESCO Finland
Removal of fixed intravenous catheter
34.5
10.5
13
*
D72.8
ICD-10 Finland
Other specified disorders of white blood cells
34.5
10.5
13
*
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
4.8
10.4
25
58
H02AB09
ATC
hydrocortisone; systemic
12.2
10.3
18
16
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
3.5
10.2
40
133
WZC30
NOMESCO Finland
Teaching
3.6
9.6
36
116
TGC00
NOMESCO Finland
Bronchial lavation
8.7
9.6
20
25
ZX108
NOMESCO Finland
Inhalation
31.7
9.5
12
*
A98
ICPC
Health maint/preventive medicine
0.4
9.5
109
1514
L01EL01
ATC
ibrutinib; oral
+∞
9.4
9
*
WW409
NOMESCO Finland
Other aferesis
+∞
9.4
9
*
C91.9
ICD-10 Finland
Lymphoid leukaemia, unspecified
+∞
9.4
9
*
WD305
NOMESCO Finland
Simple therapy of methastized malignancy with biomodifiers
+∞
9.4
9
*
J01MA14
ATC
moxifloxacin; systemic
3.9
9.3
30
87
WW200, ,
SPAT
0.1
8.9
*
291
A41.8
ICD-10 Finland
Other specified sepsis
12.3
8.7
15
13
J18.9
ICD-10 Finland
Pneumonia, unspecified
2.4
8.7
88
484
R59.9
ICD-10 Finland
Enlarged lymph nodes, unspecified
21.1
8.6
12
6
C81.1
ICD-10 Finland
Nodular sclerosis classical Hodgkin lymphoma
+∞
8.4
8
*
C91.4
ICD-10 Finland
Hairy-cell leukaemia
+∞
8.4
8
*
C82.1
ICD-10 Finland
Follicular lymphoma grade II
+∞
8.4
8
*
9732/3-C42.1
ICD-O-3
Plasma cell myeloma of bone marrow
+∞
8.4
8
*
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
6.8
8.3
20
32
TPX10
NOMESCO Finland
Implantation of vascular injection port
9.5
8.2
16
18
TPH04
NOMESCO Finland
Cathetrisation of vein
2.6
8.1
58
269
K03.82
ICD-10 Finland
Split tooth for reasons other than trauma
0.0
8.0
*
223
FB1BD
NOMESCO Finland
Extensive CT examination of arteria pulmonalis
3.9
8.0
25
71
A05AA02
ATC
ursodeoxycholic acid; oral
15.8
7.8
12
8
L04AD01
ATC
ciclosporin; systemic
15.8
7.8
12
8
A41.5
ICD-10 Finland
Sepsis due to other Gram-negative organisms
7.2
7.8
18
27
J02AC03
ATC
voriconazole; systemic
46.8
7.8
9
*
WF002
NOMESCO Finland
Radical radiotherapy
46.8
7.8
9
*
H02AB07
ATC
prednisone; oral
2.8
7.7
43
175
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
4.6
7.7
19
45
GD1AD
NOMESCO Finland
Thorax CT examination
4.7
7.6
18
41
JN4JR
NOMESCO Finland
Whole body extensive metabolic PET with CT
+∞
7.3
7
*
C95.9
ICD-10 Finland
Leukaemia, unspecified
+∞
7.3
7
*
1AA09, ,
NOMESCO Finland
+∞
7.3
7
*
WD325
NOMESCO Finland
Demanding therapy of methastized malignancy with biomodifiers
+∞
7.3
7
*
153
Kela drug reimbursment
Lenalidomid
+∞
7.3
7
*
9733/3-C42.1
ICD-O-3
Plasma cell leukemia of bone marrow
+∞
7.3
7
*
YA1AD
NOMESCO Finland
CT examination of head and neck for dose design of radiotherapy
+∞
7.3
7
*
9591/3-C77.9
ICD-O-3
Malignant lymphoma, non-Hodgkin, NOS, of lymph node, NOS
+∞
7.3
7
*
TNE25
NOMESCO Finland
Drill biopsy of bone marrow, pelvis
16.5
7.3
11
7
R91
ICD-10 Finland
Abnormal findings on diagnostic imaging of lung
3.2
7.1
30
104
UGC12
NOMESCO Finland
Flexible bronchoscopy
3.5
6.8
25
79
A41.9
ICD-10 Finland
Sepsis, unspecified
4.3
6.8
18
45
UJF32
NOMESCO Finland
Coloscopy
2.4
6.6
58
293
B01AB10
ATC
tinzaparin; parenteral
3.8
6.6
21
60
J17.3*B59
ICD-10 Finland
Pneumonia due to Pneumocystis carinii
72.0
6.5
7
*
TDM10
NOMESCO Finland
Puncture of maxillary antrum
6.7
6.3
15
24
9940/3-C42.1
ICD-O-3
Hairy cell leukemia, NOS, of bone marrow
+∞
6.3
6
*
YL1AD
NOMESCO Finland
CT examination of pelvis for dose design of radiotherapy
+∞
6.3
6
*
TPJ00
NOMESCO Finland
Biopsy of superficial lymph node
+∞
6.3
6
*
L02BB03
ATC
bicalutamide; oral
+∞
6.3
6
*
WW402
NOMESCO Finland
Leucoferesis
+∞
6.3
6
*
ZX070
NOMESCO Finland
Intensity modified radiotherapy
+∞
6.3
6
*
C84.0
ICD-10 Finland
Mycosis fungoides
+∞
6.3
6
*
PJ2AE
NOMESCO Finland
Lymphnode ultrasound examination
+∞
6.3
6
*
C83.00
ICD-10 Finland
Lymphocytic lymphoma
+∞
6.3
6
*
C03CA01
ATC
furosemide; systemic
2.1
6.2
101
653
D64.9
ICD-10 Finland
Anaemia, unspecified
2.6
6.2
39
169
ZXC50
NOMESCO Finland
Cryotherapy
9.0
6.1
12
14
GD1AA
NOMESCO Finland
Thorax X-ray examination
2.1
6.1
102
663

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
59
22
37.40
89.42
3.0
1.5
—
—
—
0
0
60
25
33.65
87.53
1.7
1.5
—
—
—
0
0
70
63
16.43
70.59
1.5
1.3
—
—
—
0
0
76
112
10.25
53.35
1.6
1.3
—
—
—
0
0
74
108
10.21
52.27
1.6
1.4
—
—
—
0
0
81
133
9.47
51.89
1.5
1.7
—
—
—
0
0
51
9
75.00
45.96
1.5
1.0
—
—
—
0
0
81
213
5.66
30.93
4.3
2.2
1.51
1.62
%
0.56
75
189
69
161
5.98
30.01
5.2
2.1
56.44
60.47
e9/l
0.51
56
131
28
7
45.99
23.35
2.2
1.6
35.15
46.84
%
—
28
7
29
16
20.91
19.78
1.2
1.1
—
—
—
0
0
28
16
20.08
18.87
1.3
1.5
—
—
—
0
0
24
34
7.87
16.48
1.4
1.4
—
—
—
0
0
20
6
36.72
16.06
1.3
1.5
—
—
—
0
0
20
6
36.72
16.06
2.5
3.0
—
—
—
0
0
99
457
3.28
15.49
11.1
3.8
—
—
—
0
0
22
12
20.37
15.06
8.4
4.0
—
—
—
0
0
40
108
4.37
13.89
2.7
1.4
—
—
—
0
0
114
614
2.95
12.97
17.3
5.5
0.44
0.65
%
3.64
108
558
114
618
2.93
12.75
22.4
5.6
—
—
—
0
0
115
631
2.90
12.49
17.8
5.4
1.85
2.93
%
6.74
109
573
115
635
2.87
12.28
18.5
5.9
9.22
8.92
%
0.23
109
576
20
15
14.64
12.23
1.1
1.0
—
—
—
0
0
21
19
12.18
11.85
1.3
1.5
150.50
285.55
u/ml
—
8
11
27
60
5.04
11.82
3.7
1.8
0.82
2.46
ug/l
0.72
27
44
89
1392
0.36
11.69
4.1
5.4
2.56
2.53
mmol/l
0.12
72
1236
115
648
2.79
11.61
18.1
5.7
32.60
25.30
%
3.79
109
591
11
0
+∞
11.56
9.5
0.0
—
—
—
0
0
84
1332
0.37
10.86
4.0
4.8
1.27
1.42
mmol/l
1.43
70
1184
86
1348
0.37
10.79
4.6
4.8
4.38
4.37
mmol/l
0.02
73
1200
20
21
10.43
10.53
3.5
1.5
—
—
—
0
0
17
15
12.25
9.76
6.1
9.0
12.62
11.33
mg/l
0.37
17
15
86
1321
0.39
9.57
5.5
6.8
42.62
41.36
mmol/mol
0.52
76
1188
9
0
+∞
9.44
1.4
0.0
—
—
—
0
0
29
83
3.91
9.19
1.5
1.7
1.48
1.45
g/l
0.04
20
75
106
641
2.37
8.35
16.8
5.4
51.85
59.21
%
4.19
100
587
109
671
2.35
8.19
15.8
5.1
0.57
0.62
e9/l
1.02
91
573
117
743
2.36
8.17
46.0
5.9
3.15
4.41
e9/l
11.08
111
644
109
674
2.33
8.07
15.8
5.1
0.03
0.04
e9/l
3.52
91
578
16
19
9.04
7.98
1.1
1.1
—
—
—
0
0
110
688
2.31
7.86
16.0
5.3
2.01
1.81
e9/l
0.34
98
599
87
1284
0.44
7.71
4.9
4.4
1.47
1.26
mmol/l
1.83
71
1130
11
6
19.27
7.69
2.4
1.3
—
—
—
0
0
39
151
2.96
7.67
7.1
2.7
5.01
7.19
umol/l
1.76
31
129
18
28
6.95
7.61
1.8
1.3
—
—
—
0
0
109
697
2.22
7.17
19.4
5.3
0.14
0.20
e9/l
5.34
96
602
19
49
4.17
6.88
1.3
1.7
—
—
—
0
0
15
21
7.62
6.84
1.3
1.1
—
—
—
0
0
99
1368
0.46
6.82
6.2
4.9
6.15
6.14
mmol/l
0.02
86
1193
17
29
6.30
6.78
4.4
1.3
—
—
—
0
0
14
18
8.26
6.74
3.5
1.6
33.29
33.78
pg
0.13
14
18
14
18
8.26
6.74
7.2
1.1
—
—
—
0
0
6
0
+∞
6.28
10.0
0.0
0.49
—
umol/l
—
6
0
111
749
2.06
5.99
19.8
6.7
1.21
1.21
mmol/l
0.02
94
633
18
52
3.70
5.59
1.8
1.2
—
—
—
0
0
123
1539
0.49
5.49
82.3
21.6
33.35
39.83
%
15.11
115
1387
123
1539
0.49
5.49
78.1
21.5
3.73
4.46
e12/l
21.81
118
1470
13
21
6.53
5.48
7.5
2.5
51.62
61.52
%
0.94
13
21
8
5
16.56
5.45
3.5
2.0
46.44
66.70
%
—
8
5
8
5
16.56
5.45
1.1
1.0
—
—
—
0
0
42
203
2.35
5.23
2.0
2.3
—
—
—
0
0
71
424
2.04
5.21
10.3
2.3
—
—
—
0
0
114
1451
0.51
5.10
41.4
14.4
—
—
—
0
0
30
126
2.62
5.01
6.5
4.0
7.46
7.41
ph
—
5
11
60
342
2.07
4.96
2.9
1.6
—
—
—
0
0
93
1256
0.52
4.94
4.2
4.4
2.33
2.04
mu/l
1.14
84
1090
9
10
9.35
4.83
1.3
1.6
—
—
—
0
0
8
7
11.83
4.82
7.6
1.1
—
—
—
0
0
52
288
2.08
4.61
5.1
1.7
2.95
1.32
mg/l
1.13
47
225
14
387
0.31
4.59
3.4
3.4
—
—
—
0
0
34
160
2.35
4.47
1.9
1.6
—
—
—
0
0
29
128
2.48
4.38
6.7
4.0
4.94
5.18
kpa
0.88
29
120
10
16
6.51
4.35
1.6
3.7
—
—
—
0
0
45
241
2.11
4.34
1.7
1.3
1.80
2.74
g/l
3.27
40
128
29
130
2.44
4.24
9.9
8.8
—
—
—
0
0
55
322
1.97
4.15
1.7
1.3
—
—
—
0
0
86
1157
0.55
4.06
71.9
17.5
15.52
15.34
%
0.30
86
1128
34
169
2.22
3.93
16.1
3.8
2.14
1.90
mmol/l
0.19
28
134
10
19
5.48
3.88
1.2
1.2
—
—
—
0
0
34
172
2.17
3.77
16.1
3.8
5.46
5.91
kpa
1.56
34
165
69
449
1.81
3.72
3.6
3.1
13.49
174.52
e6/l
0.61
54
355
67
433
1.82
3.69
12.6
3.2
7.41
7.40
ph
0.14
18
62
53
318
1.90
3.69
2.8
2.7
526.91
561.13
mosm/kgh2o
0.56
47
265
30
147
2.22
3.59
9.9
4.0
—
—
—
0
0
64
417
1.78
3.40
3.7
3.0
0.54
0.59
e6/l
0.10
50
322
8
14
5.90
3.37
2.5
1.1
—
—
—
0
0
16
60
2.81
3.31
1.8
1.2
—
—
—
0
0
21
92
2.43
3.23
7.4
4.1
—
—
—
0
0
60
391
1.76
3.16
3.7
2.9
—
—
—
0
0
76
1012
0.60
3.01
5.3
4.3
—
—
—
0
0
8
17
4.85
2.95
2.0
1.1
33603.75
17618.45
e6/l
—
8
11
6
9
6.83
2.88
13.3
1.2
—
—
—
0
0
6
10
6.14
2.71
1.2
1.0
—
—
—
0
0
8
19
4.34
2.70
2.0
1.1
13386.88
2776.38
e6/l
—
8
13
23
114
2.15
2.69
3.3
2.2
31.29
31.12
u/l
0.02
17
94
99
764
1.58
2.61
20.0
18.5
1.40
1.46
inr
0.23
31
202
48
312
1.71
2.51
32.8
4.3
—
—
—
0
0
11
38
3.00
2.45
19.6
5.2
1.55
1.84
mg/l
0.58
11
32
6
12
5.12
2.42
1.3
1.0
—
—
—
0
0
5
8
6.37
2.38
2.0
1.1
—
—
—
0
0
5
8
6.37
2.38
1.4
2.0
4691.00
2253.75
u/ml
—
5
8
5
8
6.37
2.38
2.0
1.1
—
—
—
0
0
71
516
1.58
2.38
4.5
3.6
95.57
128.05
e6/l
0.18
55
386
48
318
1.67
2.33
2.7
2.2
4.90
4.54
e6/l
0.12
43
286
12
47
2.65
2.31
5.0
1.3
33.55
35.98
g/l
0.64
12
37
10
34
3.04
2.31
5.2
2.8
—
—
—
0
0
78
993
0.65
2.26
4.0
3.5
15.16
15.05
pmol/l
0.12
70
861
31
183
1.82
2.24
1.6
1.8
—
—
—
0
0
25
138
1.93
2.21
24.0
7.2
1.63
1.48
mmol/l
0.25
25
132
21
111
1.99
2.10
11.5
2.9
1.24
1.22
mmol/l
0.46
21
87
0
57
0.00
2.09
0.0
1.3
—
—
—
0
0
6
16
3.83
1.95
2.0
1.1
—
—
—
0
0
23
379
0.56
1.91
3.6
2.7
0.68
0.84
ug/l
0.92
18
266
6
17
3.60
1.85
2.2
1.2
—
—
—
0
0
59
435
1.50
1.80
2.1
2.3
3.07
2.84
mg/l
0.33
51
363
37
527
0.64
1.71
3.3
3.9
35.04
7.54
mg/mmol
0.80
22
336
15
78
2.00
1.59
28.8
2.8
0.75
0.66
%
0.58
15
78
35
497
0.64
1.58
3.3
3.3
180.70
434.23
mg/l
0.56
22
328
22
131
1.76
1.57
2.1
1.8
361.27
348.81
nmol/l
0.10
22
113
16
86
1.93
1.55
1.6
1.1
—
—
—
0
0
36
504
0.65
1.52
2.8
3.2
6.21
7.32
mmol/l
1.23
28
412
15
80
1.94
1.49
28.8
2.8
1.06
1.16
%
0.27
15
80
23
142
1.70
1.46
20.7
3.4
5.02
4.47
kpa
0.67
23
134
71
563
1.40
1.45
3.0
2.7
671.14
144.70
ug/l
4.20
64
498
5
16
3.18
1.44
1.2
1.1
—
—
—
0
0
34
235
1.54
1.39
4.0
3.1
0.75
1.93
e6/l
1.43
20
133
57
710
0.73
1.24
4.1
4.0
1.94
2.18
ug/l
0.38
50
610
59
467
1.37
1.19
3.5
3.1
—
—
—
0
0
23
337
0.64
1.19
3.8
3.7
1.02
1.02
kg/l
—
6
62
8
39
2.09
1.16
4.3
2.0
52.38
34.28
umol/l
—
8
32
8
39
2.09
1.16
4.0
2.1
—
—
—
0
0
7
30
2.38
1.13
1.4
1.3
48.00
69.92
mmol/l
—
7
25
8
40
2.04
1.13
1.4
1.1
—
—
—
0
0
28
198
1.48
1.05
27.3
6.6
103.71
104.34
mmol/l
0.26
28
198
7
35
2.03
1.01
1.0
1.1
—
—
—
0
0
0
29
0.00
0.98
0.0
1.1
—
—
—
0
0
7
37
1.92
0.95
57.1
2.9
—
—
—
0
0
7
130
0.52
0.91
1.0
1.5
—
—
—
0
0
6
29
2.10
0.90
3.3
2.1
105.00
105.66
mmol/l
—
6
29
6
29
2.10
0.90
3.3
2.1
4.03
4.16
mmol/l
—
6
29
6
29
2.10
0.90
3.3
2.1
—
—
—
0
0
17
113
1.55
0.85
5.8
3.3
—
—
—
0
0
26
190
1.42
0.84
9.6
9.4
1.98
1.82
mmol/l
0.05
17
155
0
24
0.00
0.79
0.0
1.1
—
—
—
0
0
46
373
1.30
0.79
1.8
1.8
905.63
1158.47
nmol/l
1.18
39
284
6
34
1.79
0.77
1.5
3.4
—
—
—
0
0
20
274
0.70
0.76
1.4
1.2
0.97
2.04
u/ml
—
6
65
9
54
1.70
0.75
2.7
4.2
—
—
—
0
0
13
84
1.59
0.74
15.8
14.7
—
—
—
0
0
70
605
1.24
0.72
34.5
8.1
0.02
0.00
e9/l
1.02
62
488
7
42
1.69
0.69
4.4
1.7
112.57
135.10
g/l
—
7
30
5
27
1.87
0.69
79.8
1.9
63.40
72.04
%
—
5
27
0
21
0.00
0.60
0.0
1.8
—
—
—
0
0
60
685
0.82
0.59
2.2
2.1
90.84
93.69
pmol/l
0.17
36
347
5
88
0.56
0.57
2.4
2.3
14.90
15.66
nmol/l
—
5
80
12
84
1.46
0.50
14.8
9.9
24.82
25.21
mmol/l
0.12
12
78
107
990
1.17
0.50
5.4
4.3
—
—
—
0
0
111
1039
1.15
0.42
7.1
4.3
22.00
13.08
mm/h
3.48
105
915
8
58
1.39
0.42
1.1
1.6
—
—
—
0
0
17
132
1.31
0.42
1.4
1.3
—
—
—
0
0
0
15
0.00
0.41
0.0
1.9
—
—
—
0
0
0
16
0.00
0.41
0.0
2.4
—
290.88
—
0
16
0
17
0.00
0.41
0.0
2.4
—
—
—
0
0
7
102
0.68
0.40
1.4
1.4
—
—
—
0
0
7
105
0.65
0.40
1.4
1.2
—
—
—
0
0
0
18
0.00
0.40
0.0
1.5
—
—
—
0
0
0
19
0.00
0.39
0.0
1.5
—
—
—
0
0
0
19
0.00
0.39
0.0
1.5
—
—
—
0
0
0
19
0.00
0.39
0.0
1.5
—
—
—
0
0
0
19
0.00
0.39
0.0
1.5
—
—
—
0
0
33
383
0.83
0.38
4.2
4.0
0.00
0.00
estimate
-0.00
18
110
5
80
0.62
0.36
1.6
2.3
74.00
367.86
ug/l
—
5
73
7
96
0.72
0.31
1.6
1.5
—
—
—
0
0
15
121
1.26
0.29
4.5
7.8
—
—
—
0
0
72
673
1.11
0.26
4.0
3.8
0.00
0.01
estimate
0.50
21
132
5
38
1.32
0.23
1.0
1.3
—
—
—
0
0
34
306
1.13
0.23
3.5
3.6
—
—
—
0
0
5
41
1.22
0.22
1.4
1.7
—
—
—
0
0
41
375
1.12
0.21
4.1
3.7
—
—
—
0
0
0
11
0.00
0.21
0.0
1.1
—
142.09
—
0
11
0
11
0.00
0.21
0.0
1.2
—
—
—
0
0
0
11
0.00
0.21
0.0
1.5
—
0.07
—
0
11
0
10
0.00
0.21
0.0
1.9
—
—
—
0
0
0
12
0.00
0.21
0.0
1.4
—
—
—
0
0
9
115
0.77
0.20
5.7
3.1
—
—
—
0
0
0
14
0.00
0.20
0.0
1.4
—
—
—
0
0
57
534
1.09
0.19
3.2
3.5
—
5.87
—
0
23
72
685
1.08
0.17
4.0
3.8
0.00
0.00
estimate
-0.00
21
114
71
677
1.07
0.16
6.0
5.1
0.00
0.00
estimate
-0.00
20
118
51
480
1.08
0.15
5.9
4.1
—
—
—
0
0
8
95
0.84
0.14
2.7
2.7
—
—
—
0
0
12
138
0.86
0.13
3.3
2.7
—
—
—
0
0
19
172
1.12
0.12
1.3
1.2
—
—
—
0
0
11
96
1.15
0.10
3.3
3.7
—
—
—
0
0
6
58
1.04
0.08
2.0
2.4
3.95
4.29
pmol/l
—
6
49
7
67
1.05
0.08
5.7
4.6
—
—
—
0
0
6
70
0.85
0.08
1.7
1.2
—
18.16
—
0
5
69
675
1.03
0.05
5.2
4.2
44.73
54.09
ng/l
0.33
64
510
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
8
85
0.94
0.00
1.4
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
3.46
—
0
5
0
5
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
6
0.00
-0.00
0.0
6.7
—
—
—
0
0
0
9
0.00
-0.00
0.0
2.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.4
—
0.36
—
0
5
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.8
—
—
—
0
0
5
50
1.00
-0.00
2.0
1.9
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
2.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
2.8
—
46640.00
—
0
5
0
7
0.00
-0.00
0.0
7.9
—
23.93
—
0
7
0
7
0.00
-0.00
0.0
3.6
—
4.10
—
0
7
0
7
0.00
-0.00
0.0
4.7
—
—
—
0
0
0
7
0.00
-0.00
0.0
9.6
—
1534.29
—
0
7
0
7
0.00
-0.00
0.0
1.1
—
122.38
—
0
7
0
7
0.00
-0.00
0.0
9.0
—
753.29
—
0
7
0
7
0.00
-0.00
0.0
1.6
—
24.57
—
0
7

Mortality – FinRegistry

This endpoint is excluded (different definition than used in FinnGen).

Relationships between endpoints

Index endpoint: C3_CIRCULATING_LYMPHOID – Rare circulating lymphoid malignancy

GWS hits: -

This endpoint is excluded (different definition than used in FinnGen).