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Use of rivastigmine

ADMED_ACHEI_RIVASTIGMINE

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Medicine purchases: ATC N06DA03

1 out of 7 registries used, show all original rules.

5421

4. Check minimum number of events

Min. number of events 3
5421

5. Include endpoints

None

5421

6. Filter based on genotype QC (FinnGen only)

5421

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

First used in FinnGen datafreeze
DF2

Case counts by codes

FinnGen case counts by registry codes:

Not enough data for upset plot.

Full data table

Summary Statistics

-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

All Female Male
Number of individuals 5421 2665 2756
Unadjusted period prevalence (%) 1.06 0.91 1.21
Median age at first event (years) 78.83 79.32 78.36

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
4316
Matched controls
43125
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
G30.9
ICD-10 Finland
Alzheimer disease, unspecified
10.3
323.0
1179
1518
307
Kela drug reimbursment
Tacrine, donepezil, rivastigmine, galantamine and other major and expensive drugs used to treat Alzheimer's disease
26.1
323.0
2402
1978
N06DX01
ATC
memantine; oral
15.2
323.0
2318
3054
F00.10*G30.1
ICD-10 Finland
Primary degenerative dementia of the Alzheimer's type, senile onset without additional symptoms
10.2
323.0
983
1207
N06DA03
ATC
rivastigmine; oral, transdermal
+∞
323.0
4316
363
N05AX08
ATC
risperidone; systemic
6.2
323.0
1219
2587
N06DA02
ATC
donepezil; oral
6.7
323.0
1343
2705
N05AH04
ATC
quetiapine; oral
5.4
323.0
1251
3031
P20
ICPC
Memory disturbance
5.2
323.0
1910
5732
G30.1
ICD-10 Finland
Alzheimer disease with late onset
14.3
323.0
2127
2741
N04BA02
ATC
levodopa and decarboxylase inhibitor; oral
7.9
299.5
740
1096
G20
ICD-10 Finland
Parkinson disease
8.3
270.2
644
893
110
Kela drug reimbursment
Parkinson's disease and comparable movement disrorders
8.5
255.6
596
794
G30.8
ICD-10 Finland
Other Alzheimer disease
8.3
251.1
596
816
P70
ICPC
Dementia
8.4
244.6
577
781
SPAT1053
SPAT
Memory test
3.2
240.4
1693
7197
R41.8
ICD-10 Finland
Other and unspecified symptoms and signs involving cognitive functions and awareness
4.2
233.2
1035
3009
F00.10
ICD-10 Finland
Primary degenerative dementia of the Alzheimer's type, senile onset without additional symptoms
8.7
183.5
418
525
F02.39*G20
ICD-10 Finland
Dementia in Parkinson's disease without information on additional symptoms
27.4
182.1
254
98
G30.0
ICD-10 Finland
Alzheimer disease with early onset
14.9
172.5
297
213
F00.20*G30.8
ICD-10 Finland
Dementia in Alzheimer's disease, atypical or mixed type without additional symptoms
7.0
168.6
445
698
G30
ICD-10 Finland
Alzheimer disease
9.9
165.7
348
378
N87
ICPC
Parkinsonism
11.4
154.6
301
282
F03
ICD-10 Finland
Unspecified dementia
3.5
135.6
711
2279
N04BA03
ATC
levodopa, decarboxylase inhibitor and COMT inhibitor; oral
13.9
133.4
236
179
N06DA04
ATC
galantamine; oral
5.4
133.1
429
861
A28
ICPC
Limited function/disability NOS
2.4
129.7
1455
7524
SPAT1245
SPAT
Provision of support and information to patient’s family members
3.7
123.0
607
1842
F00.00*G30.0
ICD-10 Finland
Primary degenerative dementia of the Alzheimer's type, presenile onset without additional symptoms
13.6
115.0
205
158
N06AB10
ATC
escitalopram; oral
2.9
112.4
797
3130
N06AX11
ATC
mirtazapine; oral
2.2
110.3
1552
8784
N04BD01
ATC
selegiline; oral
8.4
107.4
247
310
F0019, G301
ICD-10 Finland
NA
9.1
103.7
226
259
SPAT1217
SPAT
Assessment of need for services (elderly/care support)
2.6
96.6
842
3708
R41.3
ICD-10 Finland
Other amnesia
4.4
90.7
351
847
SPAT1216
SPAT
Assessment of functional ability
2.2
87.9
1178
6385
R53
ICD-10 Finland
Malaise and fatigue
2.1
86.7
1308
7450
N05BA04
ATC
oxazepam; oral
2.0
81.2
1283
7408
F02.39
ICD-10 Finland
Dementia in Parkinson's disease without information on additional symptoms
68.9
76.6
88
13
N04BD02
ATC
rasagiline; oral
13.7
75.4
133
100
WYA30
NOMESCO Finland
Preparations for expected poor cooperation
3.0
75.0
471
1675
SPAT1234
SPAT
Support of social functional capacity
2.8
70.9
513
1999
N02BE01
ATC
paracetamol; systemic, rectal
2.0
69.3
3616
30954
G31.8
ICD-10 Finland
Other specified degenerative diseases of nervous system
14.0
68.3
119
87
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
1.8
68.1
1757
11920
F00.20
ICD-10 Finland
Dementia in Alzheimer's disease, atypical or mixed type without additional symptoms
6.0
65.3
187
321
F06.7
ICD-10 Finland
Mild cognitive disorder
3.6
63.7
314
932
F00.9
ICD-10 Finland
Dementia in Alzheimer disease, unspecified
7.7
63.5
152
203
WYA20
NOMESCO Finland
Home visit
4.4
59.6
230
550
N04BC04
ATC
ropinirole; oral
8.4
59.1
134
164
TAB00
NOMESCO Finland
Lumbar puncture
4.7
58.9
208
455
AA1AD
NOMESCO Finland
CT of head and brain
1.8
58.5
1392
9076
193
Kela drug reimbursment
Rasagiline
13.1
57.7
103
80
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
1.9
57.5
994
5805
SPAT1137
SPAT
Taking care of patient’s/customer’s hygiene
2.3
56.8
617
2967
A06AD11
ATC
lactulose; oral
1.8
53.5
1102
6814
F05.1
ICD-10 Finland
Delirium superimposed on dementia
6.3
48.5
133
216
N05AH03
ATC
olanzapine; systemic
3.7
48.5
225
635
SPAT1222
SPAT
Counselling/guidance promoting independent living
1.8
47.6
998
6164
F009, G309
ICD-10 Finland
NA
7.2
47.5
118
167
R41.0
ICD-10 Finland
Disorientation, unspecified
2.8
44.2
307
1155
N06AB04
ATC
citalopram; systemic
1.8
43.2
919
5680
N06AX26
ATC
vortioxetine; oral
3.6
42.2
199
569
XA800
NOMESCO Finland
Neuropsychological investigation
4.4
41.4
157
369
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
1.7
41.0
1113
7388
Z03.3
ICD-10 Finland
Observation for suspected nervous system disorder
2.6
40.6
327
1339
SPAT1254
SPAT
Administration of medicine
1.7
39.7
904
5686
130
Kela drug reimbursment
Malignant tumour
0.3
38.6
70
2476
N04BC05
ATC
pramipexole; oral
2.2
38.0
421
2021
N05BA06
ATC
lorazepam; systemic, sublingual
2.4
38.0
335
1440
A04
ICPC
Weakness/tiredness general
1.8
36.5
732
4413
F00.00
ICD-10 Finland
Primary degenerative dementia of the Alzheimer's type, presenile onset without additional symptoms
11.7
36.4
68
59
I95.1
ICD-10 Finland
Orthostatic hypotension
2.4
36.2
323
1395
N04BX02
ATC
entacapone; oral
8.7
36.2
79
92
S01.0
ICD-10 Finland
Open wound of scalp
2.1
36.2
428
2114
AA1BG
NOMESCO Finland
Standard MRI examination of brain with high intensity magnet
2.5
36.0
292
1199
SAD01
NOMESCO Finland
Assessment of need for oral health care, standard
2.2
34.6
377
1795
F02.30
ICD-10 Finland
Dementia in Parkinson's disease without additional symptoms
51.7
34.4
41
8
SPAT1229
SPAT
Assessment of need for aid
1.9
33.9
543
3023
N03AG01
ATC
valproic acid; systemic, rectal
2.7
33.6
243
933
SPAT1292
SPAT
Other function in accordance with SHToL (Finnish classification of nursing interventions)
1.9
33.3
517
2846
L28
ICPC
Limited function/disability (L)
1.6
32.1
978
6622
G25.9
ICD-10 Finland
Extrapyramidal and movement disorder, unspecified
5.5
31.6
95
175
SPAT1304
SPAT
Counselling and guidance related to ageing
1.8
30.5
539
3099
SPAT1301
SPAT
No procedures
1.5
29.5
1449
10935
R55
ICD-10 Finland
Syncope and collapse
1.7
28.5
648
4029
F0009, G300
ICD-10 Finland
NA
7.9
28.3
65
83
Z02.4
ICD-10 Finland
Examination for driving licence
0.6
28.1
520
8016
SPAT1101
SPAT
Orthostatic test
2.1
27.5
350
1776
J01DB01
ATC
cefalexin; oral
1.4
27.4
2965
25973
G91.2
ICD-10 Finland
Normal-pressure hydrocephalus
3.4
27.3
138
419
H02AB02
ATC
dexamethasone; systemic
0.3
26.2
73
2107
J01EA01
ATC
trimethoprim; systemic
1.5
26.2
1253
9350
R1250
NOMESCO Finland
Evaluation of functional capability
4.1
26.1
104
259
SAB01
NOMESCO Finland
Restricted oral and dental health check by dental hygienist or dental assistant
2.2
26.0
267
1235
F0014, G301
ICD-10 Finland
NA
10.7
26.0
50
47
F0029, G308
ICD-10 Finland
NA
9.7
25.6
52
54
N05AD01
ATC
haloperidol; systemic
2.5
25.6
208
854
N39.0
ICD-10 Finland
Urinary tract infection, site not specified
1.6
25.0
805
5481
SPAT1360
SPAT
Extensive global examination
1.9
24.9
397
2195
U04
ICPC
Incontinence urine
2.1
24.6
306
1540
S72.0
ICD-10 Finland
Fracture of neck of femur
2.0
24.5
348
1843
Z75.5
ICD-10 Finland
Holiday relief care
3.4
24.0
119
357
SPAT1252
SPAT
Overall medication plan or its review
1.8
23.9
422
2414
F21
ICPC
NA
3.6
23.3
109
312
NFB20
NOMESCO Finland
Primary partial prosthetic replacement of hip joint using cement, other or unspecified
2.2
23.2
235
1081
J18.9
ICD-10 Finland
Pneumonia, unspecified
1.4
22.9
1440
11263
A29
ICPC
General symptom/complaint other
1.7
22.7
539
3381
G04BD12
ATC
mirabegron; oral
1.7
22.5
521
3242
F00
ICD-10 Finland
Dementia in Alzheimer disease
6.3
22.2
59
94
J01CA08
ATC
pivmecillinam; oral
1.4
22.2
1566
12487
N04BC09
ATC
rotigotine; transdermal
9.3
22.2
46
50
N07AA06
ATC
NA
80.4
21.7
24
*
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
1.4
21.6
1589
12752
F00.1
ICD-10 Finland
Dementia in Alzheimer disease with late onset
8.8
21.5
46
53
S06.0
ICD-10 Finland
Concussion
1.7
21.4
445
2681
R25.1
ICD-10 Finland
Tremor, unspecified
2.7
21.1
147
556
C10AA01
ATC
simvastatin; oral
1.4
21.0
2282
19499
H02AA02
ATC
fludrocortisone; oral
4.2
20.6
79
191
F00.14
ICD-10 Finland
Primary degenerative dementia of the Alzheimer's type, senile onset other additional symptoms of mixed type
8.4
20.6
45
54
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
1.9
20.5
307
1660
SPAT1246
SPAT
Screening of depression or other psychiatric problem
3.0
20.5
123
422
SPAT1306
SPAT
Counselling and guidance related to nutrition and weight management
1.6
20.2
603
4010
B03BA03
ATC
hydroxocobalamin; parenteral
1.8
19.8
381
2239
Z29
ICPC
Social problem NOS
3.1
19.8
110
360
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
1.5
19.8
739
5179
SPAT1284
SPAT
Extensive health certificate
2.9
19.4
122
432
W19
ICD-10 Finland
Unspecified fall
1.7
19.3
444
2754
N02AA05
ATC
oxycodone; systemic
1.5
19.3
799
5727
S70.0
ICD-10 Finland
Contusion of hip
2.1
19.3
226
1108
SPAT1050
SPAT
Extensive neurological examination
2.6
18.8
136
525
N30.0
ICD-10 Finland
Acute cystitis
1.5
18.7
657
4538
N03AE01
ATC
clonazepam; systemic
2.0
18.3
226
1134
F02.32
ICD-10 Finland
Dementia in Parkinson's disease other additional symptoms, mainly hallucinations
44.1
18.2
22
5
F001, G301
ICD-10 Finland
NA
6.9
17.9
44
64
A04AA02
ATC
granisetron; systemic, transdermal
0.2
17.7
22
952
SPAT1251
SPAT
Organisation of medication
1.9
17.1
246
1309
WD105
NOMESCO Finland
Cystostatic therapy of methastized malignancy
0.2
17.0
12
734
F02.80
ICD-10 Finland
Dementia in another specified disease that is classified elsewhere without additional symptoms
50.1
17.0
20
*
R42
ICD-10 Finland
Dizziness and giddiness
1.4
16.8
1066
8256
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
1.4
16.6
840
6243
F0230, G20
ICD-10 Finland
NA
90.3
16.6
18
*
N28
ICPC
Limited function/disability (N)
2.9
16.5
100
346
J44.8
ICD-10 Finland
Other specified chronic obstructive pulmonary disease
0.6
16.5
268
4305
WD125
NOMESCO Finland
Demanding cystostatic therapy of methastized malignancy
0.2
16.3
11
692
F00.19
ICD-10 Finland
Dementia in Alzheimer's disease with late onset without information about additional symptoms
8.0
16.2
36
45
N06AB06
ATC
sertraline; oral
1.8
16.2
264
1471
A06AC01
ATC
ispaghula (psylla seeds); oral
1.4
16.1
1055
8206
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
0.7
16.0
490
6898
G04CA02
ATC
tamsulosin; oral
1.4
15.9
1201
9555
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
1.3
15.8
1748
14724
F32.9
ICD-10 Finland
Depressive episode, unspecified
1.8
15.8
278
1587
A98
ICPC
Health maint/preventive medicine
1.3
15.4
3204
29448
R91
ICD-10 Finland
Abnormal findings on diagnostic imaging of lung
0.6
15.2
196
3335
A03FA01
ATC
metoclopramide; systemic, rectal
0.7
14.8
391
5668
AAF05
NOMESCO Finland
Ventriculoperitoneal shunt
3.0
14.8
87
298
I67.3
ICD-10 Finland
Progressive vascular leukoencephalopathy
2.6
14.7
104
399
U07.1
ICD-10 Finland
Emergency use of U07.1 | COVID-19, virus identified
1.8
14.5
247
1395
N02AJ06
ATC
codeine and paracetamol; systemic
0.7
14.2
623
8264
KMAK
NOMESCO Finland
NA
1.3
14.2
1293
10549
R06.0
ICD-10 Finland
Dyspnoea
0.7
14.0
693
9021
R99
ICD-10 Finland
Other ill-defined and unspecified causes of mortality
2.4
14.0
120
513
P29
ICPC
Psychological sympt/compl other
2.6
13.7
101
396
SPAT1285
SPAT
Provision of consultation response
1.8
13.7
226
1265
N06AX16
ATC
venlafaxine; oral
1.7
13.6
265
1564
SPAT1220
SPAT
Assessment of need for rehabilitation and/or rehabilitation plan
1.7
13.6
305
1874
111
Kela drug reimbursment
Epilepsy and comparable convulsive disorders
1.9
13.3
209
1150
N29
ICPC
Neurological sympt/complt other
2.6
12.8
92
356
G21.9
ICD-10 Finland
Secondary parkinsonism, unspecified
5.0
12.8
40
80
G04CB01
ATC
finasteride; oral (testosterone-5-alpha reductase inhibitors)
1.4
12.8
642
4742
C34.1
ICD-10 Finland
Malignant neoplasm: Upper lobe, bronchus or lung
0.1
12.7
8
528
N39.4
ICD-10 Finland
Other specified urinary incontinence
1.6
12.7
379
2512
F0232, G20
ICD-10 Finland
NA
70.0
12.6
14
*
E0000UV
ATC
NA
1.3
12.5
1325
11000
F05.9
ICD-10 Finland
Delirium, unspecified
2.1
12.5
136
651
R44.1
ICD-10 Finland
Visual hallucinations
4.0
12.5
49
124
F01.2
ICD-10 Finland
Subcortical vascular dementia
3.7
12.5
54
149
112
Kela drug reimbursment
Severe psychotic and other severe mental disorders
1.8
12.4
207
1161
SAD02
NOMESCO Finland
Assessment of need for oral health care, extensive
2.7
12.3
85
324
SPAT1139
SPAT
Nutrition survey
2.0
12.2
163
848
S00.0
ICD-10 Finland
Superficial injury of scalp
2.3
12.2
108
470
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
1.4
12.0
594
4371
XX3DW
NOMESCO Finland
Time consuming IT work
0.5
11.8
123
2215
N06AX21
ATC
duloxetine; oral
1.6
11.7
284
1789
SPAT1231
SPAT
Assessment of adjustments needed in living environment
2.0
11.5
144
728
D07AA02
ATC
hydrocortisone; topical
1.5
11.5
439
3070
F06.0
ICD-10 Finland
Organic hallucinosis
7.1
11.5
27
38
R11
ICD-10 Finland
Nausea and vomiting
1.6
11.4
343
2272
SPAT1226
SPAT
Implementation of occupational therapy rehabilitation plan
1.9
11.4
158
834
M04AA01
ATC
allopurinol; systemic
0.7
11.2
399
5497
N99
ICPC
Neurological disease other
3.0
11.1
61
202
SPAT1156
SPAT
Guidance concerning treatment of rash and skin
1.4
11.0
638
4827
N04BC06
ATC
cabergoline; oral (dopamine agonists)
5.8
11.0
30
52
SPAT1307
SPAT
Psychosocial counselling and guidance
2.3
10.8
99
441
AA5EN
NOMESCO Finland
Brain reseptor or transprot protein distribution isotope imaging
8.2
10.8
23
28
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
1.3
10.8
1074
8812
R03BB04
ATC
tiotropium bromide; inhalant
0.6
10.7
247
3687
B01AC30
ATC
platelet aggregation inhibitors excl. heparin - combinations
1.5
10.6
410
2874
SCA01
NOMESCO Finland
Simple analysis and advice of nutrition with regard to dentistry
1.4
10.6
589
4425
C79.8
ICD-10 Finland
Secondary malignant neoplasm of other specified sites
0.3
10.5
19
668
N04BB01
ATC
amantadine; oral
2.7
10.5
68
252
SPAT1276
SPAT
Outlining of treatment with patient or their family members
2.0
10.1
125
633
SPAT1253
SPAT
Initiation, adjustment, discontinuation or repetition of medication
1.3
10.0
1192
9988
R56.8
ICD-10 Finland
Other and unspecified convulsions
1.8
10.0
162
907
UGC12
NOMESCO Finland
Flexible bronchoscopy
0.6
9.9
148
2430
C34.3
ICD-10 Finland
Malignant neoplasm: Lower lobe, bronchus or lung
0.1
9.7
*
351
SPAT1153
SPAT
Removal of sutures
0.8
9.6
782
9585
F02.34
ICD-10 Finland
Dementia in Parkinson's disease, other additional symptoms of mixed type
55.1
9.6
11
*
XF606
NOMESCO Finland
Ortostatic test
3.1
9.5
49
157
SAA01
NOMESCO Finland
Simple examination of mouth
1.2
9.5
1762
15502
C03DA01
ATC
spironolactone; oral
0.7
9.4
310
4338
F02.3
ICD-10 Finland
Dementia in Parkinson disease
100.2
9.4
10
*
F0022, G308
ICD-10 Finland
NA
17.5
9.4
14
8
SPAT1244
SPAT
Occupational therapy
2.8
9.4
59
214
G31.9
ICD-10 Finland
Degenerative disease of nervous system, unspecified
5.6
9.3
26
47
F002, G308
ICD-10 Finland
NA
8.0
9.3
20
25
G04CB02
ATC
dutasteride; oral
1.5
9.2
314
2149
G40.9
ICD-10 Finland
Epilepsy, unspecified
1.9
9.2
132
709
H02AB06
ATC
prednisolone; systemic
0.8
9.1
1353
15531
SPAT1250
SPAT
Comprehensive monitoring of chronic illness
1.3
9.1
1187
10028
F0011, G301
ICD-10 Finland
NA
7.7
9.1
20
26
A10AB05
ATC
insulin aspart; parenteral (insulins and analog. for injection, fast-acting)
1.5
9.1
285
1913
F00.2
ICD-10 Finland
Dementia in Alzheimer disease, atypical or mixed type
11.5
9.0
16
14
A69
ICPC
General and Unspecified, Other reason for encounter NEC
1.9
9.0
133
721
8070/3-C34.9
ICD-O-3
Squamous cell carcinoma, NOS, of lung, NOS
0.1
9.0
5
355
R35
ICD-10 Finland
Polyuria
1.6
8.9
253
1660
F05.0
ICD-10 Finland
Delirium not superimposed on dementia, so described
4.3
8.9
31
72
359
Kela drug reimbursment
Mirabegroni
3.1
8.8
45
144
SPAT1221
SPAT
Guidance concerning rehabilitation services and livelihood
2.4
8.7
70
294
F0013, G301
ICD-10 Finland
NA
14.0
8.7
14
10
F00.11
ICD-10 Finland
Primary degenerative dementia of the Alzheimer's type, senile onset other additional symptoms, mainly paranoidism
7.6
8.6
19
25
WX212
NOMESCO Finland
Femoral plexus blockade
2.0
8.6
107
546
F29
ICD-10 Finland
Unspecified nonorganic psychosis
2.7
8.5
56
212
F00.0
ICD-10 Finland
Dementia in Alzheimer disease with early onset
20.0
8.5
12
6
G23.1
ICD-10 Finland
Progressive supranuclear ophthalmoplegia [Steele-Richardson-Olszewski]
6.4
8.5
21
33
R41
ICD-10 Finland
Other symptoms and signs involving cognitive functions and awareness
2.8
8.4
52
189
WF049
NOMESCO Finland
Radiotherapy of metastasis
0.4
8.4
26
709
D38.1
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Trachea, bronchus and lung
0.4
8.3
38
889
N04AA02
ATC
biperiden; systemic
2.6
8.3
58
226
SPAT1104
SPAT
Monitoring of emergency patient
1.5
8.3
263
1769
J69.0
ICD-10 Finland
Pneumonitis due to food and vomit
1.9
8.3
119
640
N06BA04
ATC
methylphenidate; oral
10.7
8.3
15
14
N05AH02
ATC
clozapine; systemic
4.7
8.2
26
55
AA5DR
NOMESCO Finland
Brain metabolism PET with CT
14.5
8.2
13
9
S01
ICD-10 Finland
Open wound of head
2.5
8.1
60
243
4912B
ICD-9 Finland
Chronic bronchitis, Obstructive chronic bronchitis[BRONCHITIS OBSTRUCTIVA CUM EMPHYSEMATE]
0.2
8.0
5
328
R1230
NOMESCO Finland
Neuropsychological evaluation of need and possibilities to rehabilitation
4.8
8.0
25
52
WX402
NOMESCO Finland
General anaesthesia
0.6
8.0
168
2558
WZC20
NOMESCO Finland
Multidisciplinary treatment meeting
0.4
8.0
39
890
R33
ICD-10 Finland
Retention of urine
1.4
8.0
418
3104
G23.9
ICD-10 Finland
Degenerative disease of basal ganglia, unspecified
6.3
8.0
20
32
S01.41
ICD-10 Finland
Open wound in the temple-jaw region
2.8
8.0
47
166
J44.1
ICD-10 Finland
Chronic obstructive pulmonary disease with acute exacerbation, unspecified
0.5
7.9
49
1031
G04BD08
ATC
solifenacin; oral
1.4
7.9
316
2234
Z50.9
ICD-10 Finland
Care involving use of rehabilitation procedure, unspecified
1.8
7.9
127
712
SPAT1167
SPAT
Insertion of urinary catheter
1.6
7.9
195
1236
F0024, G308
ICD-10 Finland
NA
9.4
7.8
15
16
S72.1
ICD-10 Finland
Pertrochanteric fracture
1.7
7.8
160
968
C34.31
ICD-10 Finland
Malignant tumor of the lower lobe, bronchus or lung epidermoid carcinoma
0.0
7.7
*
191
J01MA02
ATC
ciprofloxacin; systemic
1.2
7.7
1565
13811
G04BD10
ATC
darifenacin; oral
2.7
7.7
49
181
R32
ICD-10 Finland
Unspecified urinary incontinence
1.8
7.7
125
703
G40.22
ICD-10 Finland
Complex partial epileptic seizure with secondary generalization
2.2
7.6
72
329
F00.24
ICD-10 Finland
Dementia in Alzheimer's disease, atypical or mixed type other additional symptoms of mixed type
8.0
7.6
16
20
-2
ICPC
NA
2.5
7.6
54
215
Z01.9
ICD-10 Finland
Special examination, unspecified
1.6
7.5
182
1146
F00.13
ICD-10 Finland
Primary degenerative dementia of the Alzheimer's type, senile onset other additional symptoms, mainly depression
8.8
7.5
15
17
Z02.7
ICD-10 Finland
Issue of medical certificate
1.5
7.5
224
1488
R03AK03
ATC
[D] fenoterol & other drugs for obstructive airway dis; inhalant
0.6
7.5
165
2488
K59.0
ICD-10 Finland
Constipation
1.5
7.4
267
1847
J44.9
ICD-10 Finland
Chronic obstructive pulmonary disease, unspecified
0.6
7.4
105
1743
AA5NK
NOMESCO Finland
Tractography within white matter of central nervous system
80.1
7.4
8
*
8000/3-C34.9
ICD-O-3
Neoplasm, malignant of lung, NOS
0.3
7.4
11
430
WZC30
NOMESCO Finland
Teaching
0.7
7.4
181
2669
FN2BA
NOMESCO Finland
Percutaneous transluminal coronary angioplasty with stent (includes balloon pre-dilation)
0.6
7.3
82
1444
N40
ICD-10 Finland
Hyperplasia of prostate
1.2
7.3
1039
8832
N06AX12
ATC
bupropion; oral
2.3
7.3
61
264
117
Kela drug reimbursment
Leukaemia and other malignant diseases of the blood and bone marrow, and malignant diseases of the lymphatic tissue
0.5
7.3
62
1176
R2110
NOMESCO Finland
Giving the first information
1.6
7.3
181
1153
WW500
NOMESCO Finland
Blood transfusion
0.5
7.2
47
972
F00.22
ICD-10 Finland
Dementia in Alzheimer's disease, atypical or mixed type other additional symptoms, mainly hallucinations
7.9
7.1
15
19
LAITO
NOMESCO Finland
NA
5.0
7.1
21
42
N04BC02
ATC
pergolide; oral
6.0
7.1
18
30
NFB40
NOMESCO Finland
Primary total prosthetic replacement of hip joint using hybrid technique
0.5
7.0
58
1110
SPAT1262
SPAT
Handing over of treatment supplies
1.3
7.0
687
5590
CA1TM
NOMESCO Finland
Calculation of intraocular lens power
0.3
7.0
14
465
A78
ICPC
Infectious disease other/NOS
2.7
7.0
45
167
SPAT1263
SPAT
Sampling
1.2
7.0
1506
13329
SAA02
NOMESCO Finland
Basic examination of mouth
1.2
7.0
1478
13059
D12
ICPC
Constipation
1.7
6.9
150
919
AA1AA
NOMESCO Finland
Head X-ray examination
2.7
6.9
45
169
K02.1
ICD-10 Finland
Caries of dentine
1.2
6.9
1269
11058
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
1.6
6.9
177
1135
L01BC06
ATC
capecitabine; oral
0.4
6.9
24
624
F01.20
ICD-10 Finland
Subcortical vascular dementia without additional symptoms
2.5
6.8
50
203
T91.8
ICD-10 Finland
Sequelae of other specified injuries of neck and trunk
40.1
6.8
8
*
I25.9
ICD-10 Finland
Chronic ischaemic heart disease, unspecified
1.3
6.7
698
5719
R02
ICPC
Shortness of breath/dyspnoea
0.7
6.7
261
3551
Z20.8
ICD-10 Finland
Contact with and exposure to other communicable diseases
2.0
6.7
83
425
A01
ICPC
Pain general/multiple sites
1.4
6.7
285
2045
R03AK07
ATC
formoterol and budesonide; inhalant
0.7
6.6
282
3785
WZC00
NOMESCO Finland
Planning of intervention or health care consultation
0.8
6.6
629
7609
AAG20
NOMESCO Finland
Stereotactic intracranial implantation of electrodes
12.2
6.6
11
9
WF003
NOMESCO Finland
Adjuvant radiotherapy
0.4
6.5
26
638
E86
ICD-10 Finland
Volume depletion
1.7
6.5
138
843
H25.8
ICD-10 Finland
Other senile cataract
0.8
6.5
438
5518
Z51.0
ICD-10 Finland
Radiotherapy session
0.1
6.5
*
245
A04AA01
ATC
ondansetron; systemic, rectal
0.6
6.5
71
1256
SPAT1014
SPAT
Treatment of eyes
1.9
6.5
92
496
S01.1
ICD-10 Finland
Open wound of eyelid and periocular area
1.9
6.5
90
482
R63.4
ICD-10 Finland
Abnormal weight loss
1.6
6.4
140
861
F0234, G20
ICD-10 Finland
NA
69.9
6.4
7
*
M01AC06
ATC
meloxicam; systemic, rectal
1.2
6.4
1138
9876
N30.9
ICD-10 Finland
Cystitis, unspecified
1.4
6.4
245
1721
203
Kela drug reimbursment
Chronic asthma and similar chronic obstructive pulmonary diseases
0.8
6.4
493
6104
S18
ICPC
Laceration/cut
0.8
6.4
1139
12953
J01CA04
ATC
amoxicillin; systemic
1.2
6.3
2597
24225
U28
ICPC
Limited function/disability (U)
2.2
6.3
58
264
F00.09
ICD-10 Finland
Primary degenerative dementia of the Alzheimer's type, presenile onset information on additional symptoms is lacking
8.1
6.3
13
16
J96.1
ICD-10 Finland
Chronic respiratory failure
0.4
6.3
31
702
D01BA02
ATC
terbinafine; oral; topical
1.2
6.3
754
6278
L03AA13
ATC
pegfilgrastim; parenteral
0.4
6.3
20
536
SPAT1224
SPAT
Implementation of speech therapy rehabilitation plan
2.3
6.2
54
238
N18.9
ICD-10 Finland
Chronic kidney disease, unspecified
0.7
6.2
180
2574
S00.9
ICD-10 Finland
Superficial injury of head, part unspecified
2.3
6.2
52
227
T03
ICPC
Loss of appetite
4.1
6.2
22
54
C34.11
ICD-10 Finland
Malignant tumor of the anterior, bronchial or pulmonary epidermoid carcinoma
0.2
6.2
*
254
SPAT1111
SPAT
Planning of analgesia
2.2
6.2
57
261
T90.5
ICD-10 Finland
Sequelae of intracranial injury
2.9
6.2
34
118
I50.1
ICD-10 Finland
Left ventricular failure
0.7
6.1
134
2020
SPAT1059
SPAT
Spirometry at the office
0.5
6.1
63
1135
K59.1
ICD-10 Finland
Functional diarrhoea
1.5
6.1
181
1204
SPAT1325
SPAT
Vaccination
1.2
6.1
1458
12982
L15
ICPC
Knee symptom/complaint
0.8
6.1
409
5158
AEA50
NOMESCO Finland
Adjustment of implanted neurostimulator
10.0
6.0
11
11
WF002
NOMESCO Finland
Radical radiotherapy
0.5
6.0
55
1021

Mortality – FinRegistry

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

Index endpoint: ADMED_ACHEI_RIVASTIGMINE – Use of rivastigmine

GWS hits: -

This endpoint is excluded from FinRegistry analyses (omitted endpoint).