Knuckle pads

M13_KNUCKLEPADS

No definition available.

Endpoint definition

↥

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps	FinnGen
Phenotype data	519972
1. Apply sex-specific rule None	519972
2. Check conditions None	519972
3. Check pre-conditions, main-only, mode, registry filters Registry filters: Hospital discharge: ICD-10 — M72.1 Cause of death: ICD-10 — M72.1 2 out of 7 registries used, show all original rules.	60
4. Check minimum number of events None	60
5. Include endpoints None	60
6. Filter based on genotype QC (FinnGen only)	55

Control definitions (FinnGen only)

Control exclude: M13_SOFTTISSUE

Extra metadata

Level in the ICD hierarchy: 4
First used in FinnGen datafreeze: DF2
Parent code in ICD-10: M72

NAME	M13_KNUCKLEPADS
CONTROL_EXCLUDE	M13_SOFTTISSUE
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX
INCLUDE
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10	M721
HD_ICD_9	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
HD_ICD_8	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10	M721
COD_ICD_9	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
COD_ICD_8	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

Similar endpoints

↥

List of similar endpoints to Knuckle pads based on the number of shared cases.

Similar with more cases:

Similar with less cases:

None

Case counts by codes

↥

FinnGen case counts by registry codes:

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

Key figures

	All	Female	Male
Number of individuals
Whole population	435	219	216
Only index persons	400	203	197
Unadjusted period prevalence (%)
Whole population	0.01	0.01	0.01
Only index persons	0.01	0.01	0.01
Median age at first event (years)
Whole population	-	54.15	51.83
Only index persons	52.14	53.44	50.80

-FinnGen-

Key figures

	All	Female	Male
Number of individuals	55	27	28
Unadjusted period prevalence (%)	0.01	0.01	0.01
Median age at first event (years)	55.72	52.39	58.92

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log₁₀(p-value) ≥ 6.

Matched cohort

Matched cases
60: Matched controls
600

Code

Vocabulary

Description

Odds Ratio

-log₁₀(p)

N matched cases

N matched controls

M72.1

ICD-10 Finland

Knuckle pads

+∞

86.1

M75.1

ICD-10 Finland

Rotator cuff syndrome

8.2

13.9

NDM10

NOMESCO Finland

Palmar fasciotomy of hand

+∞

13.0

N02AX02

ATC

tramadol; systemic, rectal

6.5

11.3

150

M54.5

ICD-10 Finland

Low back pain

5.1

9.2

109

N03AX16

ATC

[U] pregabalin

5.7

9.0

M72.0

ICD-10 Finland

Palmar fascial fibromatosis [Dupuytren]

26.0

6.9

S18

ICPC

Laceration/cut

4.3

6.9

182

R10.4

ICD-10 Finland

Other and unspecified abdominal pain

4.0

6.6

133

N02AE01

ATC

buprenorphine; parenteral, sublingual, transdermal

6.0

6.1

LabWAS

↥

N Cases

N Controls

-log₁₀(p)

cases

controls

cases

controls

unit

-log₁₀(p)

N cases

N controls

(3006315) Basophils [#/volume] in Blood

196

3.32

4.85

4.7

6.3

0.05

0.04

e9/l

2.14

163

(3013115) Eosinophils [#/volume] in Blood

205

3.33

4.82

4.7

7.2

0.20

0.17

e9/l

0.58

176

(3019198) Lymphocytes [#/volume] in Blood

205

3.33

4.82

4.7

6.2

1.84

1.73

e9/l

0.32

181

(40760892) CBC W Ordered Manual Differential panel - Blood

189

3.26

4.76

4.6

5.8

—

(3001604) Monocytes [#/volume] in Blood

197

3.07

4.30

4.8

6.3

0.57

0.59

e9/l

0.15

165

(3013650) Neutrophils [#/volume] in Blood by Automated count

261

3.29

4.27

5.3

12.2

4.47

4.34

e9/l

0.11

218

(3015399) Transferrin receptor.soluble [Mass/volume] in Serum or Plasma

3.18

4.24

2.9

1.9

2.41

3.24

mg/l

1.12

(3016417) Amylase.pancreatic [Enzymatic activity/volume] in Serum or Plasma

3.85

4.08

3.6

1.8

50.29

34.29

u/l

0.53

(3018095) Leukocytes [#/volume] in Urine

182

2.81

3.74

5.0

3.3

81.48

80.29

e6/l

0.01

123

(3044938) Influenza virus A RNA [Presence] in Specimen by NAA with probe detection

3.14

3.63

1.7

—

(3022250) Lactate dehydrogenase [Enzymatic activity/volume] in Serum or Plasma by Lactate to pyruvate reaction

3.42

3.47

2.1

4.2

237.14

260.32

u/l

0.33

(3043924) Respiratory syncytial virus RNA [Identifier] in Specimen by NAA with probe detection

3.42

3.47

1.7

1.5

—

(3038288) Influenza virus B RNA [Presence] in Specimen by NAA with probe detection

3.35

3.36

1.7

—

(43054903) Holo-transcobalamin II [Moles/volume] in Serum

182

2.62

3.31

2.6

1.9

93.46

93.26

pmol/l

0.01

(3004789) Transferrin [Mass/volume] in Serum or Plasma

3.18

3.26

5.3

2.2

2.37

g/l

0.00

(3023368) Bacteria identified in Blood by Culture

129

2.61

3.11

3.6

3.9

—

(3007566) Smooth muscle Ab [Titer] in Serum

10.73

3.03

1.2

1.0

—

(3011288) Drugs identified in Urine by Screen method

10.73

3.03

2.6

1.2

—

(3029287) Urinalysis microscopic panel [#/volume] - Urine by Automated count

181

2.47

2.95

3.9

2.9

—

(3021589) Normoblasts [#/volume] in Blood

209

2.45

2.87

8.9

9.9

0.00

e9/l

0.71

164

(3013826) Glucose [Moles/volume] in Serum or Plasma

275

2.55

2.85

6.4

4.7

6.37

6.82

mmol/l

0.83

254

(3037467) Urinalysis macro (dipstick) panel - Urine

309

2.59

2.71

7.2

3.9

—

(3029879) Epithelial cells.squamous [#/volume] in Urine by Automated count

2.69

3.2

2.9

4.71

2.17

e6/l

—

(36304419) Bacteria [Presence] in Urine

140

2.35

2.53

4.3

2.8

—

(40768797) Stomach Pathology biopsy report

2.85

2.47

1.0

1.3

—

(3001079) Blood group antibody screen [Presence] in Serum or Plasma

211

2.25

2.42

3.1

2.4

—

(3030306) Epithelial cells.non-squamous [#/volume] in Urine by Automated count

2.50

2.35

3.1

2.7

0.46

1.64

e6/l

—

(3019060) Gas panel - Arterial blood

3.34

2.26

5.4

3.9

—

(3019284) Hepatitis B virus surface Ag [Presence] in Serum

2.63

2.16

2.8

1.5

—

(3013707) Erythrocyte sedimentation rate by Westergren method

327

2.30

2.12

4.3

3.6

14.14

11.85

mm/h

0.41

292

(3024561) Albumin [Mass/volume] in Serum or Plasma

211

2.11

2.08

8.9

3.7

34.80

35.38

g/l

0.20

198

(3026008) Bacteria identified in Urine by Culture

151

2.12

2.03

6.5

3.1

—

(3027945) Reticulocytes/100 erythrocytes in Blood

2.63

2.03

1.9

2.4

1.49

1.69

0.29

(3016251) Hemoglobin.gastrointestinal [Presence] in Stool

3.46

1.94

2.7

2.0

—

(46236098) ABO and Rh group [Type] in Blood by Confirmatory method

114

2.13

1.86

2.9

2.2

—

(3006093) Chlamydia trachomatis DNA [Presence] in Specimen by NAA with probe detection

4.44

1.86

3.4

1.6

—

(3001122) Ferritin [Mass/volume] in Serum or Plasma

174

2.00

1.81

6.0

2.5

90.94

133.47

ug/l

1.06

160

(3049717) Cytology report of Urine Cyto stain

3.58

1.79

2.3

3.1

—

(3021337) Troponin I.cardiac [Mass/volume] in Serum or Plasma

2.13

1.69

3.2

3.0

30.00

102.61

ng/l

0.77

(3035350) Ketones [Presence] in Urine by Test strip

214

1.93

1.68

4.5

4.1

0.00

estimate

—

(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection

262

1.94

1.65

3.1

2.9

—

(3046870) Tissue transglutaminase IgG Ab [Units/volume] in Serum

3.53

1.55

1.2

1.0

—

(36031861) Influenza virus A and B and SARS-CoV-2 (COVID-19) and Respiratory syncytial virus RNA panel - Respiratory system specimen by NAA with probe detection

3.06

1.55

1.0

1.6

—

(3042936) Bacteria identified in Isolate by Culture

2.20

1.52

2.5

2.0

—

(40762366) Oxygen capacity [Volume Fraction] in Arterial blood

2.69

1.50

8.1

10.2

—

(3000330) Specific gravity of Urine by Test strip

3.31

1.47

2.6

4.2

—

(40758558) Short blood count panel - Blood

124

1.92

1.45

3.0

8.7

—

(3017143) Hepatitis C virus Ab [Presence] in Serum

2.35

1.43

3.2

1.6

—

(3002109) Cholesterol in LDL/Cholesterol in HDL [Mass Ratio] in Serum or Plasma

0.00

1.37

0.0

1.5

—

(3021601) Nitrite [Presence] in Urine by Test strip

216

1.78

1.34

6.1

5.4

0.00

estimate

—

(3044640) Blood type and Crossmatch panel - Blood

163

1.79

1.29

2.5

2.1

—

(3002032) Base excess in Venous blood by calculation

2.34

1.27

9.3

2.9

2.99

1.72

mmol/l

—

(3022217) INR in Platelet poor plasma by Coagulation assay

228

1.74

1.27

24.1

14.2

1.31

1.30

inr

0.02

(3019832) Treponema pallidum Ab [Presence] in Serum

2.27

1.24

2.5

1.5

—

(3009261) Glucose [Presence] in Urine by Test strip

221

1.71

1.21

4.6

4.1

0.00

estimate

—

(3019550) Sodium [Moles/volume] in Serum or Plasma

493

2.39

1.15

24.3

15.6

139.53

139.73

mmol/l

0.23

473

(3023103) Potassium [Moles/volume] in Serum or Plasma

495

2.33

1.15

24.4

15.6

3.95

3.97

mmol/l

0.28

475

(3021879) Hepatitis B virus core Ab [Presence] in Serum

2.42

1.15

1.7

1.6

—

(3011397) Hemoglobin [Presence] in Urine by Test strip

1.84

1.14

3.8

4.5

—

(3022145) Colonoscopy Study observation

2.11

1.14

1.2

1.3

—

(1761868) Lipid panel - Serum or Plasma

180

0.52

1.10

2.9

2.8

—

(3022621) pH of Urine by Test strip

2.38

1.05

4.0

2.8

—

(3051552) Clostridioides difficile toxin genes [Presence] in Stool by NAA with probe detection

2.13

1.04

1.6

1.4

—

(3030981) Hyaline casts [#/volume] in Urine by Automated count

2.35

0.96

2.5

2.1

0.55

0.14

e6/l

—

(3002385) Erythrocyte distribution width [Ratio]

418

1.74

0.90

22.3

16.6

15.01

15.25

0.11

405

(3003458) Phosphate [Moles/volume] in Serum or Plasma

1.85

0.89

16.9

4.2

1.10

1.01

mmol/l

0.42

(40768804) Tissue Pathology biopsy report

188

1.57

0.86

2.4

2.3

—

(3009343) pH of Capillary blood

1.97

0.84

5.7

3.3

—

7.41

—

(3023024) Carbon dioxide [Partial pressure] in Capillary blood

1.91

0.81

5.7

3.2

5.17

5.09

kpa

—

(3044889) 12 lead EKG panel

350

1.54

0.76

3.6

3.7

—

(46235355) HIV 1 and 2 tests - Meaningful Use set

1.73

0.74

3.7

1.8

—

(3020564) Creatinine [Moles/volume] in Serum or Plasma

506

2.04

0.74

23.6

16.0

93.13

79.30

umol/l

0.65

506

(3000494) Fungus identified in Specimen by Culture

1.65

0.74

1.0

1.5

—

(3025159) Blasts/100 leukocytes in Blood

2.00

0.72

3.0

4.3

—

0.00

—

(586526) SARS-CoV-2 (COVID-19) RNA [Presence] in Nasopharynx by NAA with probe detection

1.93

0.70

1.0

1.3

—

(3001784) Prostate Specific Ag Free/Prostate specific Ag.total in Serum or Plasma

140

1.52

0.70

3.8

4.7

15.61

20.45

—

(3000991) Gas panel - Venous blood

1.67

0.68

15.6

8.7

—

(3025941) Bacteria identified in Stool by Culture

1.79

0.65

1.0

1.3

—

(3003510) Neisseria gonorrhoeae DNA [Presence] in Urine by NAA with probe detection

1.73

0.63

2.4

1.7

—

(3024950) Chlamydia trachomatis DNA [Presence] in Urine by NAA with probe detection

1.79

0.60

2.3

2.0

—

(3044491) Cholesterol non HDL [Mass/volume] in Serum or Plasma

0.00

0.59

0.0

1.4

—

(3013512) EKG study

136

1.46

0.58

3.8

4.0

—

(3051714) Fibrin D-dimer FEU [Mass/volume] in Platelet poor plasma

101

1.50

0.56

1.6

1.4

1.22

1.39

mg/l

—

(3020682) Albumin/Creatinine [Ratio] in Urine

140

1.41

0.50

5.7

3.5

8.56

9.48

mg/mmol

0.04

(3007853) Bacteria identified in Skin by Aerobe culture

1.52

0.49

3.4

1.5

—

(3024135) Streptococcus.beta-hemolytic [Presence] in Throat by Organism specific culture

1.50

0.47

1.3

1.5

—

(3014007) Fractional oxyhemoglobin in Arterial blood

1.67

0.44

17.2

11.2

94.26

93.19

—

(36660697) Celiac disease serology panel - Serum

1.67

0.44

1.0

1.2

—

(3004588) Protein electrophoresis panel - Serum or Plasma

1.61

0.43

1.0

4.2

—

(4200892) Spirometry reversibility

1.56

0.42

1.8

1.4

—

(3020630) Protein [Mass/volume] in Serum or Plasma

1.56

0.42

1.0

5.2

69.70

68.68

g/l

—

(3014576) Chloride [Moles/volume] in Serum or Plasma

1.38

0.42

12.1

7.3

104.88

104.10

mmol/l

—

(3007164) IgA [Mass/volume] in Serum or Plasma

1.46

0.42

1.2

1.6

2.34

2.83

g/l

—

(3021347) Calcium.ionized [Moles/volume] in Serum or Plasma

231

1.31

0.40

10.8

5.6

1.19

1.21

mmol/l

0.44

202

(3002256) Pathology report gross observation

1.36

0.39

1.6

1.3

—

(3029937) Albumin [Presence] in Urine by Test strip

118

1.36

0.38

5.1

4.9

0.00

estimate

—

(40761536) Microorganisms panel - Urine sediment

1.44

0.36

6.3

3.3

—

(3009035) Cobalamin (Vitamin B12) [Moles/volume] in Serum or Plasma

101

1.37

0.35

2.5

1.9

455.69

405.58

pmol/l

0.31

(3006923) Alanine aminotransferase [Enzymatic activity/volume] in Serum or Plasma

516

1.46

0.26

12.0

9.5

28.43

25.20

u/l

0.37

490

(3019800) Troponin T.cardiac [Mass/volume] in Serum or Plasma

173

1.23

0.25

2.4

4.2

48.04

42.94

ng/l

0.06

124

(3023150) Myeloperoxidase Ab [Units/volume] in Serum

0.00

0.21

0.0

2.0

—

(3010566) Parathyrin.intact [Moles/volume] in Serum or Plasma

0.00

0.21

0.0

3.6

—

(3037756) Immunofixation for Serum or Plasma

0.00

0.21

0.0

2.7

—

(3006262) Parainfluenza virus 3 RNA [Presence] in Specimen by NAA with probe detection

0.00

0.21

0.0

1.8

—

(3012158) Parainfluenza virus 2 RNA [Presence] in Specimen by NAA with probe detection

0.00

0.21

0.0

1.8

—

(3010156) C reactive protein [Mass/volume] in Serum or Plasma by High sensitivity method

0.00

0.21

0.0

2.1

—

3.34

—

(3039443) Prostate specific Ag panel - Serum or Plasma

0.00

0.21

0.0

1.8

—

(4034850) Laboratory test

0.00

0.21

0.0

9.8

—

(3013603) Prostate specific Ag [Mass/volume] in Serum or Plasma

186

1.20

0.21

4.0

4.7

1.92

1.93

ug/l

0.01

160

(3000620) Complement C3 [Mass/volume] in Serum or Plasma

0.00

0.20

0.0

1.6

—

1.30

—

(1761482) Bacteria [#/volume] in Urine by Culture

0.00

0.20

0.0

4.1

—

(3017766) Complement C4 [Mass/volume] in Serum or Plasma

0.00

0.20

0.0

1.6

—

0.26

—

(3025839) Triglyceride [Moles/volume] in Serum or Plasma

124

1.17

0.12

1.9

1.6

1.20

1.37

mmol/l

0.75

(3005785) Creatine kinase.MB [Mass/volume] in Serum or Plasma

1.07

0.09

1.0

2.4

4.70

10.51

ug/l

—

(3041096) Erythrocytes [Presence] in Urine by Automated

122

1.08

0.03

5.8

3.4

—

(3003694) ABO and Rh group [Type] in Blood

128

1.02

0.00

1.8

1.4

—

(3019902) Methicillin resistant Staphylococcus aureus [Presence] in Specimen by Organism specific culture

0.87

0.00

5.0

3.4

—

(40768795) Lymph node Pathology biopsy report

0.00

-0.00

0.0

1.1

—

(3045783) Sodium and Potassium panel [Moles/volume] - Serum or Plasma

1.00

-0.00

3.6

9.1

—

(3000034) Microalbumin [Mass/volume] in Urine

0.00

-0.00

0.0

4.8

—

11.54

—

(3010380) Borrelia burgdorferi IgG Ab [Units/volume] in Cerebral spinal fluid

0.00

-0.00

0.0

1.0

—

(40761511) CBC panel - Blood by Automated count

504

1.08

-0.00

17.2

12.4

—

(3014973) Borrelia burgdorferi IgM Ab [Units/volume] in Cerebral spinal fluid

0.00

-0.00

0.0

1.0

—

(3025130) Human papilloma virus identified in Specimen

0.00

-0.00

0.0

1.8

—

(3041642) Human coronavirus 229E RNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

2.0

—

(21492888) Glucose tolerance 2 hours gestational panel - Serum or Plasma

0.00

-0.00

0.0

1.4

—

(3051651) Icteric interference index of Serum or Plasma

0.00

-0.00

0.0

2.4

—

(3038546) Human coronavirus OC43 RNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

2.0

—

(36033641) SARS-CoV-2 (COVID-19) Ag [Presence] in Upper respiratory specimen by Rapid immunoassay

0.00

-0.00

0.0

1.5

—

(3000081) cloZAPine [Moles/volume] in Serum or Plasma

0.00

-0.00

0.0

20.3

—

1806.13

—

(3042631) Mycobacterium sp identified in Specimen

0.00

-0.00

0.0

1.8

—

(21494434) Karyotype in Bone marrow

0.00

-0.00

0.0

1.0

—

(43055361) Metamyelocytes/Leukocytes [Pure number fraction] in Blood by Manual count

0.00

-0.00

0.0

2.0

—

(3033705) Calcium.ionized [Moles/volume] in Venous blood

0.00

-0.00

0.0

3.6

—

(3036428) Adenosine deaminase [Enzymatic activity/volume] in Pleural fluid

0.00

-0.00

0.0

1.4

—

6.40

—

(40768806) Pleura Pathology biopsy report

0.00

-0.00

0.0

3.4

—

(44816752) ERBB2 gene copy number/nucleus in Tissue by FISH

0.00

-0.00

0.0

1.1

—

(40760847) Basement membrane Ab [Titer] in Serum by Immunofluorescence

0.00

-0.00

0.0

1.4

—

(40763086) Leukocyte esterase [Presence] in Urine by Automated test strip

170

1.00

-0.00

4.9

4.5

—

(3019230) Fractional oxyhemoglobin in Venous blood

0.00

-0.00

0.0

1.1

—

66.53

—

(3018006) Microscopic observation [Identifier] in Cervix by Cyto stain.thin prep

1.00

-0.00

1.4

1.3

—

(3041354) Potassium [Moles/volume] in Venous blood

0.00

-0.00

0.0

3.6

—

3.96

—

(46235689) Lupus anticoagulant aPTT, dRVVT and PT screening panel W Reflex

0.00

-0.00

0.0

2.2

—

(3038177) Helicobacter pylori Ab [Presence] in Serum

0.00

-0.00

0.0

1.1

—

(3044927) Protein electrophoresis panel - Urine

0.00

-0.00

0.0

1.0

—

(40762485) Glomerular basement membrane Ab [Units/volume] in Serum by Immunoassay

0.00

-0.00

0.0

1.2

—

(3022806) Fractional oxyhemoglobin in Capillary blood

0.00

-0.00

0.0

1.0

—

90.03

—

(3035933) Granulocytes/100 leukocytes in Blood

0.00

-0.00

0.0

1.0

—

(3035285) Chloride [Moles/volume] in Venous blood

0.00

-0.00

0.0

3.6

—

108.40

—

(3045142) Bone marrow Pathology biopsy report

0.00

-0.00

0.0

1.2

—

(3003434) Protein [Mass/volume] in Pleural fluid

0.00

-0.00

0.0

2.2

—

34.36

—

(3004383) Neutrophil cytoplasmic Ab.classic [Titer] in Serum by Immunofluorescence

0.00

-0.00

0.0

1.5

—

(3042975) Streptococcus sp identified in Isolate by Organism specific culture

0.00

-0.00

0.0

1.0

—

(3007821) Glucose [Moles/volume] in Serum or Plasma --baseline

0.00

-0.00

0.0

1.3

—

9.63

—

(3040359) Human coronavirus NL63 RNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

2.0

—

(3036782) Glucose [Moles/volume] in Pleural fluid

0.00

-0.00

0.0

1.5

—

6.58

—

(40763470) Parainfluenza virus 4 RNA [Presence] in Isolate by NAA with probe detection

0.00

-0.00

0.0

2.0

—

(40763324) Parainfluenza virus 1 RNA [Presence] in Isolate by NAA with probe detection

0.00

-0.00

0.0

2.0

—

(3025023) Rhinovirus RNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

1.4

—

(3016881) Enterovirus RNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

1.6

—

(40769539) Bacteria identified based on 16S rRNA gene [Identifier] in Specimen by Sequencing

0.00

-0.00

0.0

1.7

—

(3003181) Sodium [Moles/volume] in Urine

0.00

-0.00

0.0

1.2

—

55.67

—

(3007844) Epstein Barr virus capsid IgM Ab [Units/volume] in Serum by Immunoassay

0.00

-0.00

0.0

1.2

—

Mortality – FinRegistry

↥

Association

Association between endpoint M13_KNUCKLEPADS and mortality.

Females

No data

Males

No data

Mortality risk

Mortality risk for people of age

years, who have M13_KNUCKLEPADS.

N-year risk	Females	Males
1	No data	No data
5	No data	No data
10	No data	No data
15	No data	No data
20	No data	No data

Relationships between endpoints

↥

Index endpoint: M13_KNUCKLEPADS – Knuckle pads

GWS hits: -

Endpoint

Case Overlap

Survival Analysis

Genetic Correlations

Genetic Signals

N (Jaccard index)

HR [CI]

rg [CI]

Hits

Coloc Hits

FinRegistry

FinnGen

FinRegistry

FinnGen

Loading data

Knuckle pads

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

1. Apply sex-specific rule

2. Check conditions

3. Check pre-conditions, main-only, mode, registry filters

4. Check minimum number of events

5. Include endpoints

6. Filter based on genotype QC (FinnGen only)

Similar endpoints

Case counts by codes

Summary Statistics

-FinRegistry-

Key figures

-FinnGen-

Key figures

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

Matched cohort

LabWAS

Mortality – FinRegistry

Association

Females

Males

Mortality risk

Relationships between endpoints