ankylosing spondylitis: An autoimmune chronic inflammatory disorder characterized by inflammation in the vertebral joints of the spine and sacroiliac joints. It predominantly affects young males. Patients present with stiffness and pain in the spine.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleNone |
520210 |
2. Check conditions
|
3729 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
1 out of 7 registries used, show all original rules. |
1773 |
4. Check minimum number of eventsNone |
1773 |
5. Include endpointsNone |
1773 |
6. Filter based on genotype QC (FinnGen only) |
1773 |
Control definitions (FinnGen only)
- Control conditions
- not M13_ANKYLOSPON_ICD10
Extra metadata
- Level in the ICD hierarchy
- C
- First used in FinnGen datafreeze
- DF3
Similar endpoints
↥List of similar endpoints to
Ankylosing spondylitis, strict definition
based on the number of shared cases.
Similar with more cases:
- Ankylosing spondylitis, ICD10
- Ankylosing spondylitis
- Spondylopathies (FG)
- Spondyloarthritis
- Autoimmune diseases related-to ILD
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 8672 | 3328 | 5319 |
| Only index persons | 8532 | 3302 | 5230 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.13 | 0.10 | 0.15 |
| Only index persons | 0.17 | 0.12 | 0.20 |
| Median age at first event (years) | |||
| Whole population | 37.75 | 38.28 | 37.43 |
| Only index persons | 37.70 | 38.29 | 37.33 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 1773 | 822 | 951 |
| Unadjusted period prevalence (%) | 0.35 | 0.28 | 0.42 |
| Median age at first event (years) | 39.13 | 38.10 | 40.02 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 1586
- Matched controls
- 15858
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
281
Kela drug reimbursment
Abatacept, adalimumab, anakinra, certolizumab pegol, etanercept, golimumab, infliximab, ixekizumab, sarilumab, secukinumab and tocilizumab
158.2
323.0
921
138
NK4XE
NOMESCO Finland
Joint ultrasound examination not elsewhere classified
20.0
323.0
611
482
L04AX03
ATC
methotrexate; systemic (immunosuppressants)
28.6
323.0
888
676
L04AB01
ATC
etanercept; parenteral
109.9
323.0
439
55
H20.0
ICD-10 Finland
Acute and subacute iridocyclitis
32.7
323.0
549
252
M45
ICD-10 Finland
Ankylosing spondylitis
+∞
323.0
1586
24
A07EC01
ATC
sulfasalazine; oral, rectal
342.1
323.0
1461
524
L04AB04
ATC
adalimumab; parenteral
84.2
323.0
552
100
313
Kela drug reimbursment
Abatacept, adalimumab, anakinra, certolizumab pegol, etanercept, golimumab, infliximab, ixekizumab, sarilumab, secukinumab, tocilizumab and ustekinumab (rheumatoid diseases)
159.5
323.0
949
146
202
Kela drug reimbursment
Connective tissue diseases, rheumatoid arthritis and comparable disease
7133.0
323.0
1582
714
L04AB06
ATC
golimumab; parenteral
116.0
296.3
316
34
M46.1
ICD-10 Finland
Sacroiliitis, not elsewhere classified
69.4
289.9
331
60
L88
ICPC
Rheumatoid/seropositive arthritis
25.3
260.6
376
192
TNX10
NOMESCO Finland
Arthrocentesis, unspecified region, unspecified region
14.6
260.2
470
444
L01BA01
ATC
methotrexate; systemic (folic acid analog.)
24.0
257.9
379
205
NA6BG
NOMESCO Finland
Sacro-iliac joint MRI examination with high intensity magnet
39.6
254.4
324
102
M46.9
ICD-10 Finland
Inflammatory spondylopathy, unspecified
75.6
253.5
286
46
H02AB06
ATC
prednisolone; systemic
5.0
194.6
1089
4800
S01BA04
ATC
prednisolone; ophthalmic (corticosteroids, plain)
26.0
144.7
205
90
H22.1*M45
ICD-10 Finland
Iridocyclitis in ankylosing spondylitis
1366.6
131.2
126
*
S01BA01
ATC
dexamethasone; ophthalmic (corticosteroids, plain)
13.8
128.6
231
194
M01AH01
ATC
celecoxib; oral (coxibs)
4.8
127.0
503
1389
M01AC06
ATC
meloxicam; systemic, rectal
3.7
126.6
822
3567
L04AC10
ATC
secukinumab; parenteral
90.7
120.3
133
16
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
4.1
120.2
601
2062
M01AH05
ATC
etoricoxib; oral
3.7
118.2
1216
7426
H20.1
ICD-10 Finland
Chronic iridocyclitis
39.2
112.4
143
40
7200A
ICD-9 Finland
Ankylosing spondylitis and other inflammatory spondylopathies, Ankylosing spondylitis
390.3
110.8
110
*
L04AA13
ATC
leflunomide; oral
16.8
106.8
175
116
S01CA02
ATC
prednisolone and antiinfectives; ophthalmic (ophth., corticosteroids and antiinfectives in comb.)
35.3
106.8
139
43
NA3BG
NOMESCO Finland
Lumbar spine MRI examination with high intensity magnet
5.6
104.4
343
750
WZA10
NOMESCO Finland
Long statement of health and health related matters
23.4
98.2
143
67
GD1AA
NOMESCO Finland
Thorax X-ray examination
3.1
94.6
789
3845
L04AA11
ATC
[U] etanercept; parenteral
68.0
94.0
108
17
S01FA04
ATC
cyclopentolate; ophthalmic
27.6
90.3
125
49
L04AB05
ATC
certolizumab pegol; parenteral
76.8
89.5
101
14
P01BA02
ATC
hydroxychloroquine; oral
5.8
84.3
261
522
NF1AE
NOMESCO Finland
Hip joint ultrasound examination
12.7
84.2
155
134
S01FA02
ATC
scopolamine; ophthalmic
29.6
73.8
100
36
H02AB07
ATC
prednisone; oral
3.8
68.8
333
1035
NA6CG
NOMESCO Finland
Sacro-iliac joint extensive MRI examination with high intensity magnet
41.1
65.4
82
21
N02AX02
ATC
tramadol; systemic, rectal
2.5
65.2
752
4151
NA2AA
NOMESCO Finland
Thoracal spine X-ray examination without contrast
10.8
54.6
108
107
M01AH02
ATC
rofecoxib; oral
3.9
54.1
250
735
A02BC02
ATC
pantoprazole; systemic
2.3
53.9
1041
7176
M05.8
ICD-10 Finland
Other seropositive rheumatoid arthritis
6.3
53.0
149
258
H20.9
ICD-10 Finland
Iridocyclitis, unspecified
16.9
50.9
82
51
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
4.0
50.0
218
606
71240
ICD-8 Finland
Rheumatoid arthritis and allied conditions, Spondylitis ankylopoietica
503.1
49.7
49
*
M13.9
ICD-10 Finland
Arthritis, unspecified
4.2
48.2
199
526
ZX120
NOMESCO Finland
Intravenous
3.9
47.8
214
608
M01AE02
ATC
naproxen; oral, rectal
2.1
45.6
981
6831
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
2.3
45.2
589
3281
NA2BG
NOMESCO Finland
Thoracal spine MRI examination with high intensity magnet
8.0
44.8
105
140
NA1EA
NOMESCO Finland
Cervical spine X-ray examination with flexion
14.8
44.3
75
53
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
2.1
44.3
821
5337
L04AA17
ATC
[U] adalimumab; parenteral
49.8
44.1
53
11
M01AX17
ATC
nimesulide; oral
2.5
42.1
395
1853
NA6AA
NOMESCO Finland
Sacro-iliac joint X-ray examination
34.2
40.9
53
16
TNX00
NOMESCO Finland
Puncture and needle biopsy of soft tissue, unspecified region
9.5
40.5
85
94
M01AX01
ATC
nabumetone; oral
5.7
39.6
118
219
NA3CG
NOMESCO Finland
Lumbar spine extensive MRI examination with high intensity magnet
5.3
38.8
124
250
R4110
NOMESCO Finland
Physiotherapy
2.3
38.5
460
2421
UJF32
NOMESCO Finland
Coloscopy
2.4
37.3
392
1930
M46.8
ICD-10 Finland
Other specified inflammatory spondylopathies
37.2
37.0
47
13
NA1AA
NOMESCO Finland
Cervical spine X-ray examination without contrast
5.8
36.9
108
196
M05BA04
ATC
alendronic acid; oral
5.1
36.3
120
251
M03BX02
ATC
tizanidine; oral
2.0
36.3
1088
8267
M01CB01
ATC
sodium aurothiomalate; parenteral
14.4
35.8
61
44
M54.9
ICD-10 Finland
Dorsalgia, unspecified
2.9
35.6
243
936
TNG10
NOMESCO Finland
Puncture of knee
14.9
35.2
59
41
A02BC03
ATC
lansoprazole; oral
2.2
35.2
457
2482
M02.9
ICD-10 Finland
Reactive arthropathy, unspecified
8.8
34.4
75
89
Z01.0
ICD-10 Finland
Examination of eyes and vision
2.5
33.5
289
1276
NF1AA
NOMESCO Finland
Hip X-ray examination
4.0
33.0
141
381
M01AB05
ATC
diclofenac; systemic, rectal
2.0
32.6
1117
8717
M01AE03
ATC
ketoprofen; systemic, rectal
2.0
31.6
596
3737
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
3.3
31.3
168
547
XX9XE
NOMESCO Finland
Other ultrasound examination
12.3
30.3
55
46
L04AX01
ATC
azathioprine; systemic
3.9
29.7
128
348
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.9
29.6
665
4407
M54.5
ICD-10 Finland
Low back pain
1.9
29.2
564
3541
H04.10
ICD-10 Finland
Dry eye syndrome
3.0
29.0
184
672
M01AB01
ATC
indometacin; systemic, rectal
3.5
28.8
140
421
N02BE01
ATC
paracetamol; systemic, rectal
2.1
28.3
1311
11077
208
Kela drug reimbursment
Ulcerative colitis and Crohn's disease
3.5
28.1
139
424
NA1BA
NOMESCO Finland
Cervical spine extensive X-ray examination without contrast
13.3
27.5
48
37
N02AJ06
ATC
codeine and paracetamol; systemic
1.8
27.1
634
4223
UJF30
NOMESCO Finland
Ileoscopy through colon
2.8
27.0
192
752
M06.9
ICD-10 Finland
Rheumatoid arthritis, unspecified
6.2
27.0
74
124
L04AA01
ATC
[U] ciclosporin; systemic
7.9
26.4
61
80
ZX140
NOMESCO Finland
Intra articular
11.2
25.9
49
45
H22.1
ICD-10 Finland
Iridocyclitis in other diseases classified elsewhere
95.0
25.7
28
*
M01AB55
ATC
diclofenac, combinations; oral
3.5
25.2
121
361
4AB02
NOMESCO Finland
NA
15.3
23.8
39
26
NA1BG
NOMESCO Finland
Cervical spine MRI examination with high intensity magnet
3.2
23.6
129
424
NH3EA
NOMESCO Finland
Feet X-ray examination with load
6.5
23.5
62
99
M03BC01
ATC
orphenadrine (citrate); systemic
1.9
23.4
437
2663
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.9
23.4
394
2311
M46.0
ICD-10 Finland
Spinal enthesopathy
54.9
23.1
27
5
RK220
NOMESCO Finland
NA
27.8
22.3
30
11
S01BC03
ATC
diclofenac; ophthalmic
5.8
22.2
64
115
3640A
ICD-9 Finland
Disorders of iris and ciliary body, Acute and subacute iridocyclitis
52.8
22.1
26
5
NE1AA
NOMESCO Finland
Pelvis X-ray examination
3.6
21.6
100
290
M25.5
ICD-10 Finland
Pain in joint
1.8
21.4
459
2917
H15.1
ICD-10 Finland
Episcleritis
6.5
21.1
55
87
NG1DA
NOMESCO Finland
X-ray of knees
6.9
20.9
52
77
K50.8
ICD-10 Finland
Other Crohn disease
5.3
20.7
64
125
A07EC02
ATC
mesalazine; oral, rectal
2.9
20.5
131
477
NK5AT
NOMESCO Finland
Joint injection with ultrasound guidance not elsewhere classified
13.2
20.2
35
27
H02AB04
ATC
methylprednisolone; systemic
2.1
20.1
237
1199
4AA12
NOMESCO Finland
NA
17.5
20.0
31
18
XCW99
NOMESCO Finland
Other investigative procedure of eye
2.6
19.9
154
633
NH3AA
NOMESCO Finland
Foot and toes X-ray examination
2.7
19.7
142
559
K50.0
ICD-10 Finland
Crohn disease of small intestine
5.4
19.2
58
111
NA1CG
NOMESCO Finland
Cervical spine extensive MRI examination with high intensity magnet
5.7
19.1
55
99
M06.0
ICD-10 Finland
Seronegative rheumatoid arthritis
5.0
19.0
61
125
A02BC05
ATC
esomeprazole; systemic
1.7
18.8
587
4138
TNG11
NOMESCO Finland
Injection of diagnostic or therapeutic substance in knee
9.5
18.7
38
41
NG1AA
NOMESCO Finland
Knee X-ray examination without contrast
2.4
18.5
166
738
NB1AE
NOMESCO Finland
Shoulder ultrasound examination
5.3
18.4
56
108
J01DB01
ATC
cefalexin; oral
1.8
18.4
1277
11134
NE1CG
NOMESCO Finland
Pelvic, hip and femur extensive MRI examination with high intensity magnet
5.1
18.3
58
117
O99.89
ICD-10 Finland
Other specified diseases and conditions complicating pregnancy, childbirth and the puerperium
5.0
18.2
59
122
K02.1
ICD-10 Finland
Caries of dentine
1.6
17.8
941
7577
M79.0
ICD-10 Finland
Rheumatism, unspecified
4.1
17.8
69
172
NG1AE
NOMESCO Finland
Knee joint ultrasound exmination
8.4
17.5
38
46
NB1AA
NOMESCO Finland
Shoulder X-ray examination without contrast
2.9
17.3
108
387
SPAT1249
SPAT
Treatment-related counselling outside office
1.6
17.2
560
3971
A07EA06
ATC
budesonide; oral, local oral
3.5
17.0
82
246
NK6QA
NOMESCO Finland
Measurement of bone density from tow or more locations with X-ray
3.0
17.0
99
341
H57.1
ICD-10 Finland
Ocular pain
3.6
16.9
77
221
SAA02
NOMESCO Finland
Basic examination of mouth
1.6
16.8
1032
8562
M01AC01
ATC
piroxicam; systemic, rectal
2.1
16.6
195
982
TCF00
NOMESCO Finland
Subconjunctival therapeutic injection
27.9
16.5
22
8
WZB00
NOMESCO Finland
Telephone receipt or other advice
1.7
16.4
471
3216
TND11
NOMESCO Finland
Injection of diagnostic or therapeutic substance in joint, wrist or hand
6.8
16.4
41
62
NF2AT
NOMESCO Finland
Injection to hip joint with ultrasound guidance
12.3
16.4
29
24
TNH11
NOMESCO Finland
Injection of diagnostic or therapeutic substance in ankle joint or foot joint
7.2
16.3
39
55
M51.3
ICD-10 Finland
Other specified intervertebral disc degeneration
2.5
16.2
134
568
RK210
NOMESCO Finland
NA
30.4
16.1
21
7
NA2CG
NOMESCO Finland
Thoracal spine extensive MRI examination with high intensity magnet
8.0
16.1
36
46
S01BA07
ATC
fluorometholone; ophthalmic (corticosteroids, plain)
5.2
15.8
49
97
M07.3*L40.5
ICD-10 Finland
Other psoriatic arthropathies
4.3
15.7
58
138
H20
ICD-10 Finland
Iridocyclitis
13.1
15.7
27
21
ND2AA
NOMESCO Finland
Hand and fingers X-ray examination
2.3
15.6
152
702
SFA10
NOMESCO Finland
Fillning on one surface of tooth
1.5
15.6
834
6636
S01FA06
ATC
tropicamide; ophthalmic
85.9
15.6
17
*
M03BC51
ATC
orphenadrine, combinations; systemic
1.6
15.6
452
3089
S01CA01
ATC
dexamethasone and antiinfectives; ophthalmic (ophth., corticosteroids and antiinfectives in comb.)
1.7
15.3
383
2508
H40.5
ICD-10 Finland
Glaucoma secondary to other eye disorders
9.3
15.2
31
34
K51.9
ICD-10 Finland
Ulcerative colitis, unspecified
3.4
15.1
75
231
N03AX12
ATC
gabapentin; oral
2.0
15.0
212
1149
36400
ICD-8 Finland
Iritis, Iridocyclitis acuta
32.0
14.8
19
6
M01AB08
ATC
etodolac; oral
2.4
14.6
127
553
J01CA04
ATC
amoxicillin; systemic
1.6
14.6
1246
10988
WZC30
NOMESCO Finland
Teaching
2.0
14.6
195
1035
M07.2*L40.5
ICD-10 Finland
Psoriatic spondylitis
36.4
14.4
18
5
RF420
NOMESCO Finland
NA
6.4
14.3
37
59
M54.6
ICD-10 Finland
Pain in thoracic spine
2.4
14.2
125
549
L02
ICPC
Back symptom/complaint
2.2
14.1
147
700
L04AD01
ATC
ciclosporin; systemic
4.5
14.1
50
115
M01CB03
ATC
auranofin; oral
12.8
13.9
24
19
SFA20
NOMESCO Finland
Filling on two surfaces of tooth
1.5
13.8
924
7635
M54.8
ICD-10 Finland
Other dorsalgia
3.1
13.6
75
250
SAA01
NOMESCO Finland
Simple examination of mouth
1.5
13.4
1108
9562
NH1AE
NOMESCO Finland
Ankle joint ultrasound examination
7.8
13.4
30
39
RF120
NOMESCO Finland
NA
7.1
13.4
32
46
N03AX16
ATC
pregabalin; oral
1.7
13.3
315
2021
SPAT1256
SPAT
Intramuscular and subcutaneous injection
1.5
13.3
529
3883
SPAT1325
SPAT
Vaccination
1.6
13.3
386
2622
K51.5
ICD-10 Finland
Left sided colitis
3.2
13.2
70
227
NF1DA
NOMESCO Finland
X-ray of hips
5.4
13.2
39
74
K57.3
ICD-10 Finland
Diverticular disease of large intestine without perforation or abscess
2.0
13.2
178
945
K52.9
ICD-10 Finland
Noninfective gastroenteritis and colitis, unspecified
3.3
13.1
67
212
M07.4*K50.9
ICD-10 Finland
Arthropathy in Crohn's disease [regional enteritis]
15.2
13.1
21
14
N06AA09
ATC
amitriptyline; systemic
2.2
13.1
133
627
K50.9
ICD-10 Finland
Crohn disease, unspecified
4.4
13.1
47
110
L99
ICPC
Musculoskeletal disease other
4.7
12.9
43
93
H02AB08
ATC
triamcinolone; systemic
19.2
12.9
19
10
L34
ICPC
Musculoskeletal, Blood test
50.4
12.9
15
*
L84
ICPC
Back syndrome without radiat pain
2.8
12.8
81
296
M01AE52
ATC
naproxen and esomeprazole; oral
3.2
12.8
66
210
F01
ICPC
Eye pain
3.8
12.8
53
142
RF410
NOMESCO Finland
NA
6.1
12.7
34
57
NGF15
NOMESCO Finland
Total synovectomy of knee, arthroscopic
5.8
12.7
35
61
M35.7
ICD-10 Finland
Hypermobility syndrome
4.9
12.7
41
86
Z96.1
ICD-10 Finland
Presence of intraocular lens
2.6
12.6
93
371
J01MA02
ATC
ciprofloxacin; systemic
1.5
12.2
501
3689
A02BC01
ATC
omeprazole; systemic
1.6
12.1
335
2238
WZA90
NOMESCO Finland
Other doctors statement
1.6
11.9
327
2179
M01AH03
ATC
valdecoxib; oral
2.5
11.8
91
373
NA7CG
NOMESCO Finland
Spine and spinal cord extensive MRI examination with high intensity magnet
5.2
11.7
35
68
M13.8
ICD-10 Finland
Other specified arthritis
6.1
11.7
31
52
326
Kela drug reimbursment
Adalimumab, golimumab, infliximab and ustekinumab (intestinal diseases)
5.8
11.7
32
56
Z50.1
ICD-10 Finland
Other physical therapy
2.6
11.6
84
332
S01FA01
ATC
atropine; ophthalmic
12.6
11.6
20
16
EB1SA
NOMESCO Finland
Dental X-ray, bite-wing X-ray on one side of the mouth
1.4
11.4
833
6882
NE1BG
NOMESCO Finland
Pelvic, hip and femur MRI examination with high intensity magnet
3.5
11.3
51
148
SPAT1253
SPAT
Initiation, adjustment, discontinuation or repetition of medication
1.6
11.2
389
2746
WZC00
NOMESCO Finland
Planning of intervention or health care consultation
1.5
11.2
449
3278
NA6BM
NOMESCO Finland
Sacro-iliac joint MRI examination with 3 Tesla magnet
25.2
11.1
15
6
TNF11
NOMESCO Finland
Injection of diagnostic or therapeutic substance in hip joint
25.2
11.1
15
6
M02AA07
ATC
piroxicam; topical
1.5
11.1
442
3216
ND2BA
NOMESCO Finland
Hand and fingers extensive X-ray examination
3.9
11.1
44
114
TPH04
NOMESCO Finland
Cathetrisation of vein
1.7
10.9
265
1708
N06AX21
ATC
duloxetine; oral
1.9
10.7
165
922
NAJ12
NOMESCO Finland
Posterior reduction of fracture of cervical spine
60.4
10.6
12
*
RT171
NOMESCO Finland
NA
110.7
10.4
11
*
M07.4
ICD-10 Finland
Arthropathy in Crohn disease [regional enteritis]
110.7
10.4
11
*
M08.1
ICD-10 Finland
Juvenile ankylosing spondylitis
110.7
10.4
11
*
J01AA02
ATC
doxycycline; systemic
1.5
10.4
1123
9916
SAA03
NOMESCO Finland
Extended examination of mouth
1.4
10.3
578
4507
K50.1
ICD-10 Finland
Crohn disease of large intestine
4.2
10.3
38
93
R2110
NOMESCO Finland
Giving the first information
2.1
10.2
111
541
NA7DG
NOMESCO Finland
Spine and spinal cord very extensive MRI examination with high intensity magnet
5.3
10.2
30
58
M47.82
ICD-10 Finland
Other spondylosis, cervical region
3.0
10.1
58
199
A02BB01
ATC
misoprostol; oral
11.4
10.1
18
16
M79.7
ICD-10 Finland
Fibromyalgia
2.9
10.0
58
202
K51.3
ICD-10 Finland
Ulcerative (chronic) rectosigmoiditis
3.5
9.9
45
132
NH3DA
NOMESCO Finland
Bilateral foot X-ray examination
3.7
9.8
41
112
R06.0
ICD-10 Finland
Dyspnoea
1.6
9.7
269
1789
A03FA01
ATC
metoclopramide; systemic, rectal
1.6
9.6
245
1597
K51.8
ICD-10 Finland
Other ulcerative colitis
4.4
9.5
33
76
M07.5*K51.9
ICD-10 Finland
Arthropathy in ulcerative colitis
9.1
9.5
19
21
UJF92
NOMESCO Finland
Capsular endoscopy
3.4
9.5
44
131
71490
ICD-8 Finland
Other specified forms of arthritis, Arthritis postinfectiosa NUD
30.2
9.4
12
*
S01ED01
ATC
timolol; ophthalmic
3.5
9.4
42
122
Z01.2
ICD-10 Finland
Dental examination
1.4
9.3
594
4722
L03
ICPC
Low back symptom/complaint
1.5
9.3
311
2167
R42
ICD-10 Finland
Dizziness and giddiness
1.7
9.1
219
1402
7168A
ICD-9 Finland
Other and unspecified arthropathies, Other specified arthropathy
36.9
9.0
11
*
SPAT1263
SPAT
Sampling
1.4
8.9
554
4374
M16.7
ICD-10 Finland
Other secondary coxarthrosis
6.4
8.8
22
35
M01AE01
ATC
ibuprofen; systemic, rectal
1.6
8.7
1428
13419
SFA30
NOMESCO Finland
Filling on tree or more surfaces of tooth
1.4
8.7
588
4710
K07.60
ICD-10 Finland
Snapping jaw
2.2
8.7
83
382
M70.6
ICD-10 Finland
Trochanteric bursitis
1.9
8.7
120
642
3029
Kela drug reimbursment
Upadacitinib
50.3
8.7
10
*
P01AB01
ATC
metronidazole; oral, rectal
1.4
8.7
521
4083
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
2.0
8.6
104
530
RK250
NOMESCO Finland
NA
7.7
8.6
19
25
H26.3
ICD-10 Finland
Drug-induced cataract
7.7
8.6
19
25
RT272
NOMESCO Finland
NA
11.6
8.6
15
13
D64.9
ICD-10 Finland
Anaemia, unspecified
2.1
8.6
94
460
M06.8
ICD-10 Finland
Other specified rheumatoid arthritis
7.0
8.5
20
29
RF210
NOMESCO Finland
NA
2.9
8.5
49
170
R2130
NOMESCO Finland
Counselling and guidance which enhance independent living
2.0
8.5
107
555
Z87.1
ICD-10 Finland
Personal history of diseases of the digestive system
1.4
8.5
621
5034
RT271
NOMESCO Finland
NA
27.7
8.5
11
*
TNB11
NOMESCO Finland
Injection of diagnostic or therapeutic substance in shoulder joint
7.4
8.4
19
26
7202A
ICD-9 Finland
Ankylosing spondylitis and other inflammatory spondylopathies, Sacro-iliitis, not elsewhere classified
90.5
8.4
9
*
S01FB01
ATC
phenylephrine; ophthalmic (sympathomimetics excl. antiglaucoma prep.)
90.5
8.4
9
*
ND2DA
NOMESCO Finland
Bilateral hand X-ray examination
3.6
8.4
36
102
C10AC01
ATC
colestyramine; oral
3.2
8.3
42
135
M54.0
ICD-10 Finland
Panniculitis affecting regions of neck and back
4.0
8.3
31
78
M81.9
ICD-10 Finland
Osteoporosis, unspecified
3.5
8.2
37
109
D07AC01
ATC
betamethasone; topical
1.4
8.2
435
3323
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
1.7
8.2
174
1078
NK4AT
NOMESCO Finland
Puncture of joint with ultrasound guidance not elsewher classified
7.6
8.2
18
24
EB1AA
NOMESCO Finland
Tooth X-ray examination
1.4
8.1
820
6993
NA1DG
NOMESCO Finland
Cervical spine very extensive MRI examination with high intensity magnet
33.5
8.1
10
*
K51.1
ICD-10 Finland
Ulcerative (chronic) ileocolitis
4.5
8.1
27
61
A02BA02
ATC
ranitidine; systemic
1.6
8.0
208
1355
S01ED51
ATC
timolol, combinations; ophthalmic
2.5
8.0
62
257
H30.2
ICD-10 Finland
Posterior cyclitis
10.1
8.0
15
15
D06BB04
ATC
podophyllotoxin; topical
1.9
8.0
111
598
J01.0
ICD-10 Finland
Acute maxillary sinusitis
1.5
7.9
309
2222
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
2.4
7.9
67
291
CJE20
NOMESCO Finland
Phakoemulsification with implantation of artificial lens in posterior chamber
1.7
7.9
160
975
T84.0
ICD-10 Finland
Mechanical complication of internal joint prosthesis
3.5
7.9
35
102
M13.0
ICD-10 Finland
Polyarthritis, unspecified
4.1
7.9
29
72
A06AC01
ATC
ispaghula (psylla seeds); oral
1.5
7.8
255
1758
Z01.8
ICD-10 Finland
Other specified special examinations
1.5
7.8
277
1948
SPAT1153
SPAT
Removal of sutures
1.5
7.8
353
2614
L40.0
ICD-10 Finland
Psoriasis vulgaris
2.3
7.8
70
315
RS221
NOMESCO Finland
NA
3.8
7.8
31
83
A07EA02
ATC
hydrocortisone; rectal
3.0
7.7
42
143
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
1.5
7.7
309
2234
S12.2
ICD-10 Finland
Fracture of other specified cervical vertebra
5.6
7.7
21
38
R35
ICD-10 Finland
Polyuria
2.3
7.6
68
304
WX002
NOMESCO Finland
Sedation and analgesia
1.6
7.6
223
1502
Z71.8
ICD-10 Finland
Other specified counselling
1.5
7.6
313
2273
TCA20
NOMESCO Finland
Peribulbar therapeutic injection into orbit
18.4
7.6
11
6
M02AA10
ATC
ketoprofen; topical
1.6
7.6
193
1251
R50.9
ICD-10 Finland
Fever, unspecified
1.7
7.6
176
1114
M07.3
ICD-10 Finland
Other psoriatic arthropathies
4.5
7.6
25
56
EB1JA
NOMESCO Finland
Double panorama tomography of teeth and jaws or similar X-ray examination
6.2
7.5
19
31
D50.9
ICD-10 Finland
Iron deficiency anaemia, unspecified
2.1
7.5
83
410
K07.65
ICD-10 Finland
Temporomandibular joint-pain-dysfunction syndrome
5.8
7.5
20
35
M03BA52
ATC
carisoprodol, combinations excl. psycholeptics; oral
3.0
7.5
41
140
-44
ICPC
Preventive immunization/medic
2.0
7.5
87
439
M05BB03
ATC
alendronic acid and colecalciferol; oral
4.4
7.5
25
57
M01AA01
ATC
phenylbutazone; systemic, rectal
80.5
7.4
8
*
CK2X4
NOMESCO Finland
Optical coherence tomography (OCT) of ocular fundus
2.0
7.4
90
461
ZX112
NOMESCO Finland
Subcutaneous
3.5
7.4
32
92
N02AC04
ATC
dextropropoxyphene; oral
3.2
7.4
37
119
M02.1
ICD-10 Finland
Postdysenteric arthropathy
8.4
7.3
15
18
J99.8*M45
ICD-10 Finland
Respiratory disorders in ankylosing spondylitis
+∞
7.3
7
*
NA6DG
NOMESCO Finland
Sacro-iliac joint very extensive MRI examination with high intensity magnet
+∞
7.3
7
*
R51.80
ICD-10 Finland
Headache
1.6
7.3
203
1349
M02.8
ICD-10 Finland
Other reactive arthropathies
6.3
7.2
18
29
R07.4
ICD-10 Finland
Chest pain, unspecified
1.5
7.1
294
2132
L30.9
ICD-10 Finland
Dermatitis, unspecified
1.5
7.1
217
1473
ZX114
NOMESCO Finland
Intramuscular
3.6
7.1
30
85
WX290
NOMESCO Finland
Other blockade of nerve
1.3
7.1
716
6060
NA3BM
NOMESCO Finland
Lumbar spine MRI examination with 3 Tesla magnet
8.8
7.0
14
16
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.4
7.0
468
3708
N20.9
ICD-10 Finland
Urinary calculus, unspecified
2.9
7.0
41
146
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.3
7.0
738
6282
DM1AI
NOMESCO Finland
Cone beam CT of paranasal sinus
2.9
7.0
40
139
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
1.5
6.9
224
1541
O99.1
ICD-10 Finland
Other diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism complicating pregnancy, childbirth and the puerperium
6.4
6.9
17
27
H40.4
ICD-10 Finland
Glaucoma secondary to eye inflammation
13.8
6.9
11
8
M17.5
ICD-10 Finland
Other secondary gonarthrosis
5.0
6.8
20
40
L04AC13
ATC
ixekizumab; parenteral
11.0
6.8
12
11
H05BA01
ATC
calcitonin (salmon synthetic); nasal, parenteral
4.0
6.8
25
63
M05BA06
ATC
ibandronic acid; systemic
5.3
6.8
19
36
SPAT1202
SPAT
Intra-articular injection
3.1
6.8
35
116
Z04.8
ICD-10 Finland
Examination and observation for other specified reasons
1.6
6.7
163
1047
XX9AW
NOMESCO Finland
Production of copy from X-ray picture
2.5
6.7
51
212
L01CB
ATC
Podophyllotoxin derivatives
22.6
6.7
9
*
M54.2
ICD-10 Finland
Cervicalgia
1.9
6.6
98
539
L04AC05
ATC
ustekinumab; parenteral
6.5
6.6
16
25
GD1DD
NOMESCO Finland
High resolution CT examination of lungs
2.3
6.6
56
245
R5120
NOMESCO Finland
Preparation of an aid
3.5
6.6
29
85
J18.9
ICD-10 Finland
Pneumonia, unspecified
1.5
6.6
216
1489
NA3BA
NOMESCO Finland
Lumbar spine extensive X-ray examination without contrast
12.3
6.6
11
9
M07.5
ICD-10 Finland
Arthropathy in ulcerative colitis
12.3
6.6
11
9
WYA05
NOMESCO Finland
Emergency visit or other similar visit involving procedures
1.3
6.6
707
6014
M25.4
ICD-10 Finland
Effusion of joint
4.4
6.5
22
51
B01AB05
ATC
enoxaparin; parenteral
1.4
6.5
316
2361
J01FA10
ATC
azithromycin; systemic
1.3
6.5
850
7426
JN3BD
NOMESCO Finland
Extensive abdominal CT
1.7
6.5
129
784
L28
ICPC
Limited function/disability (L)
1.7
6.4
135
834
VALMI
NOMESCO Finland
NA
1.4
6.4
341
2591
R03AC02
ATC
salbutamol; inhalant
1.3
6.4
715
6108
L40.5
ICD-10 Finland
Arthropathic psoriasis
3.1
6.4
32
104
-1
NOMESCO Finland
NA
1.3
6.4
479
3857
H26.2
ICD-10 Finland
Complicated cataract
3.8
6.4
25
67
I10
ICD-10 Finland
Essential (primary) hypertension
1.3
6.4
557
4588
N20.0
ICD-10 Finland
Calculus of kidney
3.1
6.3
32
105
SHA01
NOMESCO Finland
Correction of physiology of bite - simple therapy visit
1.6
6.3
151
967
TNC11
NOMESCO Finland
Injection of diagnostic or therapeutic substance in elbow joint
9.3
6.3
12
13
M13.1
ICD-10 Finland
Monoarthritis, not elsewhere classified
4.6
6.3
20
44
M03.2
ICD-10 Finland
Other postinfectious arthropathies in diseases classified elsewhere
+∞
6.3
6
*
N06CA01
ATC
amitriptyline and psycholeptics; systemic
1.8
6.2
111
650
NH1AA
NOMESCO Finland
Ankle X-ray examination without contrast
1.9
6.2
91
500
NA6CF
NOMESCO Finland
Sacro-iliac joint extensive MRI examination with median intensity magnet
26.8
6.2
8
*
TNE11
NOMESCO Finland
Injection of diagnostic or therapeutic substance in sacroiliac joint
26.8
6.2
8
*
S01EA05
ATC
brimonidine; ophthalmic (sympathomimetics in glaucoma therapy)
3.7
6.2
25
69
WX110
NOMESCO Finland
Local anesthesy
1.3
6.2
1014
9121
ZXA00
NOMESCO Finland
Right side
1.4
6.2
287
2129
N02AA05
ATC
oxycodone; systemic
1.7
6.2
129
796
S01EC01
ATC
acetazolamide; systemic
3.2
6.2
30
96
SPAT1251
SPAT
Organisation of medication
2.6
6.1
41
160
S01EE03
ATC
bimatoprost; ophthalmic
4.2
6.1
21
50
XCH00
NOMESCO Finland
Eye pressure measurement
2.7
6.1
40
153
R51.81
ICD-10 Finland
Facial pain NOS
2.9
6.1
33
114
H11.3
ICD-10 Finland
Conjunctival haemorrhage
2.5
6.1
44
180
KMAK
NOMESCO Finland
NA
1.3
6.0
800
6976
J01FF01
ATC
clindamycin; systemic
1.4
6.0
355
2744
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
205
56
41.26
307.65
1.6
2.4
9.3
9.6
mg/l
0.14
161
48
1595
7251
12.95
307.65
12.7
6.1
2.1
2.0
e9/l
3.63
1548
6476
1601
7292
13.32
307.65
12.9
6.4
0.2
0.2
e9/l
1.33
1554
6498
441
481
11.87
307.65
1.6
1.6
0.9
0.3
iu/ml
0.55
114
85
1623
8016
13.11
301.79
15.0
9.5
3.8
4.1
e9/l
8.50
1568
7036
1458
6576
7.85
295.71
13.0
6.2
2.7
2.9
%
2.53
1429
6174
1465
6757
7.72
285.72
12.6
6.0
54.1
56.6
%
17.12
1432
6382
1468
6849
7.65
280.42
13.2
6.2
31.9
28.9
%
27.25
1437
6450
1689
10199
14.85
210.69
10.6
3.7
10.6
9.4
mm/h
3.83
1669
9584
1663
10428
10.59
183.01
12.0
7.3
72.1
75.2
u/l
3.45
1640
9898
154
150
11.15
140.59
1.3
1.4
23.0
30.0
iu/ml
—
5
7
1214
6675
3.60
139.27
6.3
4.2
0.0
0.0
estimate
0.50
293
1279
1217
6736
3.57
137.36
5.0
3.1
0.0
0.0
estimate
0.14
278
1202
1209
6674
3.55
136.84
4.9
3.0
0.0
0.0
estimate
0.80
268
1226
1158
6234
3.47
136.42
14.6
8.8
0.0
0.0
e9/l
0.94
1071
5143
183
279
7.20
116.45
3.6
3.7
3.8
4.0
e9/l
1.08
183
279
184
287
7.04
114.60
3.8
4.0
53.4
56.6
%
2.68
184
287
93
69
14.17
100.35
2.7
3.1
6.8
8.1
mg/l
0.74
77
60
88
62
14.88
97.73
2.5
2.4
98.4
98.1
au/ml
—
10
9
935
5334
2.59
83.49
2.6
2.3
74.2
73.6
nmol/l
0.32
893
4939
148
281
5.66
75.09
2.1
1.6
6807.6
11474.7
e6/l
1.00
114
211
155
316
5.28
72.66
1.7
1.4
—
—
—
0
0
1744
14711
12.34
63.96
22.1
11.6
14.6
21.8
mg/l
27.26
1602
11352
653
3484
2.38
62.91
6.3
3.4
0.0
0.0
estimate
1.28
287
1236
846
5304
2.14
52.47
5.5
3.1
—
—
—
0
0
407
1953
2.41
47.94
3.9
2.5
167.0
130.5
ug/g
1.15
349
1579
527
2863
2.20
45.97
6.1
3.2
1.0
1.0
kg/l
0.65
66
367
523
2887
2.15
43.41
2.6
2.1
2.9
2.8
mg/l
0.81
462
2499
466
2522
2.15
40.26
2.5
2.5
3.2
5.5
e6/l
5.04
424
2224
1522
12643
2.44
38.25
22.5
14.0
13.6
13.5
%
3.18
1511
12381
72
131
5.69
38.02
2.1
1.5
41.6
56.5
%
1.93
46
85
1751
15860
9.38
35.57
22.2
9.2
28.8
29.7
u/l
1.37
1740
15476
62
109
5.86
33.93
2.1
1.4
44.2
27.7
%
2.39
41
67
555
3385
1.93
33.40
3.1
2.9
0.2
0.4
e6/l
3.03
445
2503
1604
13876
2.64
32.87
15.4
10.2
93.4
89.5
ml/min/173m2
14.25
1442
11451
160
597
2.85
30.86
1.3
1.4
—
—
—
0
0
586
3728
1.85
30.39
3.1
3.0
27.7
109.2
e6/l
1.35
477
2831
373
2045
2.04
30.08
2.4
2.6
0.7
0.9
e6/l
0.88
249
1118
130
440
3.11
29.82
1.5
2.0
—
—
—
0
0
748
5235
1.74
27.40
5.1
6.4
1.2
1.2
mmol/l
1.59
704
4810
817
5865
1.73
27.28
5.2
7.0
1.2
1.2
mmol/l
1.46
698
4998
228
1111
2.21
24.69
2.3
2.9
1.9
1.8
%
0.86
200
1004
333
1869
1.96
24.67
2.2
2.5
13.3
14.4
umol/l
2.11
316
1739
731
5216
1.68
24.03
4.7
5.2
36.8
36.7
g/l
0.32
683
4912
35
52
6.85
22.55
1.7
1.3
5.4
6.1
%
—
11
10
227
1143
2.13
22.54
2.0
2.6
11.1
10.5
g/l
1.60
210
1050
64
175
3.76
20.50
2.4
3.2
1.2
1.2
%
0.08
50
145
825
6256
1.60
20.11
3.2
2.7
103.8
121.3
ug/l
2.18
792
5901
454
2989
1.70
19.36
1.4
1.5
2.9
2.3
g/l
5.16
306
1999
49
117
4.28
18.88
1.8
1.2
10595.2
45549.3
e6/l
0.74
37
85
1035
8358
1.57
18.66
4.3
3.6
380.4
910.1
e6/l
0.42
11
99
272
1596
1.83
17.12
2.3
2.6
22.9
24.6
%
1.15
243
1388
290
1737
1.80
17.06
2.2
2.5
2.4
2.4
g/l
0.13
273
1614
1762
16850
8.37
15.95
30.7
16.8
271.7
253.3
e9/l
25.76
1752
16518
1762
16869
8.18
15.50
30.7
16.8
4.5
4.6
e12/l
16.44
1750
16511
290
1785
1.75
15.43
1.7
1.7
1087.7
1160.0
nmol/l
0.78
230
1402
1762
16878
8.09
15.29
30.7
16.8
6.9
6.7
e9/l
5.28
1747
16513
849
6755
1.49
15.01
5.0
6.3
10.2
11.3
umol/l
1.55
804
6437
126
614
2.13
13.50
1.2
1.2
2.1
1.3
u/ml
0.15
16
52
601
4542
1.49
13.25
1.9
1.8
92.7
97.0
pmol/l
1.75
370
2520
38
105
3.68
12.07
2.7
3.1
52.6
54.7
%
0.23
24
77
93
449
2.13
10.24
1.3
2.0
1.5
1.5
g/l
0.09
71
388
1571
14622
1.65
10.18
13.6
12.5
139.5
139.7
mmol/l
1.73
1544
14289
347
2454
1.51
10.17
1.5
1.5
20.2
20.4
nmol/l
0.04
306
2165
146
829
1.83
10.09
1.8
1.6
—
—
—
0
0
281
1923
1.55
9.54
2.7
2.7
2.4
2.1
e6/l
0.16
158
1005
1572
14681
1.62
9.47
13.7
12.6
3.9
4.0
mmol/l
4.96
1539
14319
623
4972
1.39
9.44
3.3
3.4
33.5
35.7
u/l
0.26
598
4746
472
3598
1.42
9.31
2.2
2.4
3236.8
4622.8
umol/l
0.44
426
3236
46
174
2.69
8.74
1.2
1.3
—
—
—
0
0
41
147
2.83
8.62
1.5
1.5
—
—
—
0
0
139
835
1.72
7.95
1.7
2.7
68.9
67.4
g/l
1.26
130
787
190
1246
1.59
7.73
3.2
4.6
216.5
239.1
u/l
1.98
178
1186
10
13
7.73
7.12
1.6
1.5
3.7
3.8
mg/l
—
10
13
321
2400
1.41
6.84
1.2
1.3
13.4
8.9
u/ml
0.46
141
1027
465
3698
1.35
6.77
2.2
2.1
162.9
274.7
u/l
1.90
442
3511
428
3373
1.35
6.59
1.3
1.3
1.1
1.6
u/ml
0.70
115
958
102
597
1.75
6.44
1.3
1.3
168.1
220.8
miu/ml
0.74
36
283
79
435
1.85
6.11
1.6
1.6
0.2
0.2
g/l
0.25
73
411
512
4192
1.31
5.98
2.6
2.6
60.4
56.7
u/l
0.39
482
3931
422
3365
1.33
5.94
1.7
1.5
—
—
—
0
0
49
230
2.16
5.92
1.8
1.6
—
—
—
0
0
485
3953
1.31
5.83
2.4
3.3
2.3
2.3
mmol/l
1.77
439
3591
34
137
2.51
5.79
1.2
1.2
566.0
200.0
titre
—
5
25
330
2552
1.36
5.67
1.2
1.3
23.6
26.6
iu/ml
0.26
101
776
56
282
2.02
5.65
1.5
2.6
0.0
0.0
g/l
0.50
50
271
80
454
1.80
5.64
1.6
1.6
1.2
1.2
g/l
0.58
74
429
182
1268
1.49
5.62
13.1
17.0
1.4
1.2
inr
0.91
31
203
21
66
3.21
5.60
2.5
2.2
—
—
—
0
0
102
622
1.68
5.59
2.1
2.7
0.3
0.2
e6/l
0.85
95
600
36
153
2.38
5.49
1.0
1.1
—
—
—
0
0
29
113
2.59
5.31
1.0
1.0
—
—
—
0
0
859
7587
1.26
5.29
4.6
4.9
6.4
6.6
mmol/l
2.25
806
7085
56
290
1.96
5.24
1.6
1.4
—
—
—
0
0
153
1052
1.50
5.05
2.3
2.3
25.2
21.5
au/ml
—
9
81
30
122
2.48
5.05
2.1
2.5
33.1
32.7
pg
0.21
30
122
20
66
3.05
4.95
2.6
2.2
—
—
—
0
0
20
66
3.05
4.95
2.6
2.2
—
—
—
0
0
20
66
3.05
4.95
2.6
2.2
—
—
—
0
0
240
1808
1.38
4.83
1.9
1.9
—
—
—
0
0
545
4603
1.27
4.81
3.7
3.0
25.3
40.6
ng/l
2.11
324
2692
396
3217
1.30
4.76
1.8
1.8
1.0
0.9
mg/l
0.23
293
2353
63
351
1.82
4.76
2.5
3.1
—
—
—
0
0
342
2727
1.31
4.72
2.8
3.0
552.5
956.0
ng/l
2.31
274
2239
185
1339
1.43
4.70
2.0
2.1
337.8
367.0
nmol/l
1.39
170
1252
58
317
1.86
4.66
1.5
2.6
0.1
0.9
g/l
3.67
51
293
25
97
2.60
4.64
1.1
1.2
—
43.2
—
0
5
63
356
1.80
4.56
1.5
2.4
3.1
3.0
g/l
0.38
49
285
1391
13099
1.29
4.52
4.0
4.3
1.7
2.0
mu/l
1.46
1308
12297
65
372
1.78
4.51
1.5
2.3
4.2
3.8
g/l
1.30
47
277
65
372
1.78
4.51
1.5
2.3
7.3
7.2
g/l
0.15
50
294
72
426
1.72
4.46
1.3
1.1
—
—
—
0
0
72
426
1.72
4.46
1.3
1.1
—
—
—
0
0
24
94
2.57
4.39
1.1
1.2
—
2.4
—
0
5
85
531
1.63
4.31
1.8
1.8
—
—
—
0
0
307
2442
1.31
4.29
1.7
1.6
65926321.7
32113102.9
pmol/l
0.31
270
2130
64
372
1.75
4.24
1.5
2.3
—
—
—
0
0
52
286
1.84
4.13
1.6
2.5
38.6
38.5
g/l
0.04
45
260
1510
14419
1.32
4.11
20.1
12.0
40.4
41.3
%
4.29
1149
11733
137
964
1.46
4.07
1.3
1.3
—
40.5
—
0
49
8
10
8.03
4.06
1.9
2.0
—
—
—
0
0
63
370
1.73
4.04
1.9
1.7
—
—
—
0
0
247
1923
1.33
4.02
2.5
2.9
2.4
2.4
mmol/l
0.18
217
1705
48
261
1.86
3.97
1.6
2.6
0.0
0.0
g/l
0.00
42
250
43
226
1.93
3.93
1.3
1.6
—
—
—
0
0
1172
10904
1.22
3.80
3.4
3.8
14.8
14.5
pmol/l
2.65
1089
10174
21
83
2.55
3.80
2.1
2.3
0.7
2.4
u/field
1.58
12
47
14
44
3.20
3.78
1.6
2.0
—
—
—
0
0
307
2485
1.28
3.75
2.0
2.1
—
—
—
0
0
15
50
3.02
3.69
3.1
2.5
—
—
—
0
0
13
40
3.27
3.62
3.5
4.3
—
—
—
0
0
32
158
2.04
3.51
1.8
1.5
—
—
—
0
0
32
158
2.04
3.51
1.8
1.5
—
—
—
0
0
129
925
1.43
3.50
3.2
3.9
1.2
1.2
mmol/l
0.73
120
797
32
159
2.03
3.46
1.8
1.5
—
—
—
0
0
157
1170
1.38
3.41
2.5
2.3
0.2
0.2
g/l
0.58
147
1104
73
469
1.58
3.36
2.6
2.0
—
—
—
0
0
16
59
2.73
3.32
1.1
1.1
12.9
13.2
u/l
0.04
16
51
275
2232
1.27
3.28
1.9
2.0
—
—
—
0
0
202
1575
1.32
3.26
3.0
2.9
10.4
7.7
umol/l
0.43
178
1374
199
1549
1.32
3.26
4.2
6.9
1.0
1.0
mmol/l
0.11
185
1468
32
163
1.98
3.25
1.8
1.5
—
—
—
0
0
22
97
2.28
3.20
1.5
2.0
—
—
—
0
0
56
342
1.66
3.18
1.6
2.4
10.9
10.3
g/l
0.57
51
298
16
61
2.64
3.13
1.1
1.1
83.3
87.8
u/l
0.09
16
53
14
50
2.81
3.09
3.3
2.5
—
—
—
0
0
14
50
2.81
3.09
3.3
2.5
—
—
—
0
0
59
369
1.62
3.06
1.2
1.2
4.1
10.1
u/ml
—
7
62
31
160
1.95
3.05
1.8
1.5
—
—
—
0
0
18
74
2.45
3.05
1.0
1.1
1750.7
1578.1
miu/ml
0.29
18
74
1220
11496
1.20
3.05
3.4
3.3
—
—
—
0
0
49
293
1.69
3.02
1.3
1.7
—
—
—
0
0
30
154
1.96
3.00
1.4
1.3
—
—
—
0
0
58
364
1.61
2.98
1.2
1.2
1.8
2.5
u/ml
—
5
38
364
3083
1.23
2.97
2.4
2.2
—
—
—
0
0
141
1058
1.36
2.96
2.6
2.3
74.7
75.1
ml/min/173m2
0.04
46
390
694
6245
1.18
2.95
4.0
3.8
—
—
—
0
0
42
243
1.75
2.92
1.0
1.1
—
—
—
0
0
42
244
1.74
2.88
1.2
1.2
—
36.7
—
0
6
24
117
2.07
2.77
2.3
1.8
—
—
—
0
0
24
117
2.07
2.77
2.3
1.8
—
—
—
0
0
24
117
2.07
2.77
2.3
1.8
—
—
—
0
0
(40770918) von Willebrand factor (vWf).activity actual/normal in Platelet poor plasma by Immunoassay
0
75
0.00
2.75
0.0
1.7
—
127.1
—
0
70
47
286
1.66
2.74
1.2
1.2
—
—
—
0
0
105
763
1.40
2.70
2.3
2.7
98.9
141.6
ng/l
1.20
94
671
161
2045
0.77
2.67
1.7
1.7
—
—
—
0
0
94
674
1.42
2.62
1.9
2.1
38.6
40.0
u/l
0.38
89
621
64
426
1.52
2.59
2.2
1.8
—
—
—
0
0
30
163
1.85
2.58
1.9
1.5
—
—
—
0
0
22
107
2.07
2.57
1.3
1.1
—
—
—
0
0
22
107
2.07
2.57
1.3
1.1
—
—
—
0
0
156
1223
1.30
2.47
1.5
1.8
—
—
—
0
0
22
109
2.03
2.46
1.3
1.1
—
—
—
0
0
22
109
2.03
2.46
1.3
1.1
—
—
—
0
0
22
109
2.03
2.46
1.3
1.1
—
—
—
0
0
5
8
6.26
2.37
1.0
6.1
—
—
—
0
0
158
1249
1.29
2.36
1.6
1.8
—
—
—
0
0
17
79
2.16
2.25
1.5
1.4
7.4
4.0
u/l
—
10
33
47
305
1.56
2.18
1.2
1.2
—
—
—
0
0
82
596
1.39
2.16
1.6
1.6
—
—
—
0
0
109
830
1.33
2.15
1.1
1.1
—
—
—
0
0
20
102
1.97
2.10
1.9
2.0
20.2
13.3
%
—
6
48
22
391
0.56
2.03
1.4
2.0
7.5
4.8
iu/l
—
5
152
0
50
0.00
1.88
0.0
1.4
—
93.9
—
0
27
0
52
0.00
1.88
0.0
1.1
—
92.4
—
0
29
7
22
3.19
1.88
1.0
1.2
—
—
—
0
0
12
52
2.32
1.87
2.4
3.5
—
—
—
0
0
20
107
1.88
1.86
1.1
1.1
—
—
—
0
0
220
1861
1.21
1.84
1.8
2.3
30.2
29.7
s
0.62
213
1812
7
24
2.92
1.72
1.1
1.2
—
—
—
0
0
31
194
1.61
1.72
1.3
1.3
—
—
—
0
0
19
103
1.85
1.72
1.1
2.1
—
—
—
0
0
90
696
1.31
1.65
2.5
3.0
1.9
1.5
mmol/l
0.59
65
516
262
2287
1.17
1.56
4.0
3.3
652.0
575.7
ng/l
0.06
170
1527
173
1456
1.21
1.55
6.0
5.7
—
—
—
0
0
106
846
1.27
1.55
1.3
1.4
—
—
—
0
0
130
1063
1.24
1.54
7.6
8.1
1.3
1.4
mmol/l
0.19
123
1028
259
2264
1.17
1.51
1.5
1.5
—
—
—
0
0
57
418
1.38
1.50
1.9
2.3
9.2
10.3
mg/l
0.49
51
392
102
814
1.27
1.50
2.9
4.2
69.2
82.6
ng/l
0.92
96
732
11
52
2.12
1.44
1.7
1.6
—
—
—
0
0
6
22
2.73
1.43
1.0
1.1
—
—
—
0
0
36
246
1.47
1.40
1.1
1.1
—
—
—
0
0
19
111
1.72
1.39
1.0
1.1
1.7
1.1
u/l
—
6
57
89
706
1.27
1.39
1.5
1.5
—
—
—
0
0
21
127
1.66
1.36
2.4
2.0
34.5
22.9
mg/l
—
6
39
91
728
1.26
1.33
2.7
3.1
5.1
5.2
kpa
0.24
85
683
56
738
0.75
1.32
2.3
1.8
7.0
3.7
mg/l
0.53
44
509
8
34
2.36
1.29
1.9
1.1
91.6
97.9
%
—
8
34
8
34
2.36
1.29
1.8
1.1
—
—
—
0
0
36
251
1.44
1.29
1.1
1.1
—
—
—
0
0
1422
13868
1.13
1.25
3.8
3.8
5.7
5.9
mmol/l
4.56
1347
12987
10
50
2.01
1.16
1.1
2.3
—
55782.9
—
0
8
45
334
1.36
1.16
1.6
1.5
12946.7
1915.1
e6/l
0.41
40
271
45
334
1.36
1.16
1.5
1.4
31.6
13.0
e6/l
0.39
38
262
5
20
2.50
1.15
1.0
2.0
—
—
—
0
0
5
20
2.50
1.15
1.6
1.8
—
—
—
0
0
26
175
1.49
1.13
1.3
1.8
—
—
—
0
0
170
1477
1.17
1.12
3.6
3.9
31.0
30.3
%
0.45
133
1087
110
927
1.20
1.04
3.2
2.2
7.3
8.0
ug/l
0.12
98
840
33
238
1.39
1.03
1.9
2.2
138.2
135.0
g/l
0.28
23
171
1347
13146
1.10
1.01
4.6
4.8
37.2
38.9
mmol/mol
11.37
1290
12462
119
1015
1.18
1.00
3.1
4.6
209.8
20.0
ug/l
0.68
90
808
148
1287
1.16
0.98
8.1
9.4
13.2
12.8
kpa
0.39
139
1239
148
1287
1.16
0.98
8.1
9.4
5.2
5.1
kpa
0.32
139
1237
5
23
2.18
0.98
1.0
1.0
—
—
—
0
0
10
54
1.86
0.96
1.7
1.2
—
64.4
—
0
9
41
311
1.33
0.95
2.0
1.8
—
—
—
0
0
0
32
0.00
0.95
0.0
1.3
—
—
—
0
0
20
133
1.51
0.94
2.7
2.7
956.1
711.2
e6/l
0.50
12
50
11
184
0.60
0.92
1.5
1.1
—
—
—
0
0
10
55
1.82
0.92
1.0
1.0
—
—
—
0
0
146
1280
1.15
0.89
8.2
9.5
1.1
1.0
mmol/l
0.23
115
1012
147
1291
1.15
0.88
3.3
2.6
37.7
75.3
u/l
0.53
128
1136
486
4564
1.09
0.88
3.8
3.7
1.9
1.8
ug/l
0.18
440
4198
30
220
1.37
0.87
2.3
2.0
—
—
—
0
0
72
595
1.22
0.86
10.6
12.0
24.9
24.3
mmol/l
0.90
65
572
38
290
1.32
0.86
2.1
3.9
38.0
66.6
mg/l
0.66
28
226
38
290
1.32
0.86
2.1
3.9
28.3
32.8
mg/l
0.43
28
225
27
196
1.38
0.84
1.3
1.5
—
—
—
0
0
68
815
0.83
0.80
1.6
1.5
—
—
—
0
0
140
1237
1.14
0.79
3.2
3.0
—
—
—
0
0
28
208
1.35
0.77
3.3
4.3
788.6
232.8
u/ml
0.38
23
198
38
483
0.78
0.77
1.6
1.5
—
—
—
0
0
54
440
1.23
0.76
1.2
1.1
—
—
—
0
0
57
468
1.23
0.75
1.4
1.3
—
—
—
0
0
23
167
1.38
0.73
1.0
1.2
—
—
—
0
0
9
55
1.64
0.73
1.2
2.0
—
—
—
0
0
9
55
1.64
0.73
1.2
2.0
—
—
—
0
0
224
2047
1.11
0.73
3.2
3.9
0.8
0.8
mmol/l
0.66
208
1945
9
56
1.61
0.72
1.2
1.4
—
—
—
0
0
21
287
0.73
0.71
1.5
1.5
0.2
0.3
nmol/l
2.29
14
229
5
27
1.85
0.68
1.0
1.4
—
—
—
0
0
7
43
1.63
0.67
1.1
1.4
—
—
—
0
0
26
197
1.32
0.66
2.0
2.3
6.2
6.1
umol/l
0.02
16
142
11
70
1.57
0.65
1.6
1.1
264.4
519.7
u/l
0.63
11
61
36
449
0.80
0.65
1.5
1.4
—
—
—
0
0
45
368
1.23
0.64
1.4
1.4
279.7
308.3
ug/g
0.33
25
202
36
448
0.80
0.64
1.5
1.4
—
—
—
0
0
36
448
0.80
0.64
1.5
1.4
—
—
—
0
0
8
127
0.63
0.64
1.6
1.5
2.9
1.9
mmol/l
—
8
120
36
447
0.80
0.63
1.5
1.4
—
—
—
0
0
49
406
1.21
0.62
4.2
3.9
13421.9
3417.3
u/ml
0.45
43
348
0
20
0.00
0.60
0.0
1.0
—
0.0
—
0
11
0
21
0.00
0.60
0.0
3.0
—
—
—
0
0
0
21
0.00
0.60
0.0
1.0
—
—
—
0
0
0
21
0.00
0.60
0.0
1.0
—
0.0
—
0
13
0
21
0.00
0.60
0.0
1.3
—
—
—
0
0
0
22
0.00
0.59
0.0
1.2
—
—
—
0
0
0
22
0.00
0.59
0.0
1.2
—
—
—
0
0
29
228
1.28
0.58
1.8
1.7
—
—
—
0
0
0
23
0.00
0.58
0.0
2.2
—
0.5
—
0
17
0
23
0.00
0.58
0.0
1.1
—
—
—
0
0
31
387
0.80
0.58
1.3
1.5
—
—
—
0
0
29
229
1.27
0.57
1.3
1.7
—
—
—
0
0
6
36
1.67
0.56
1.0
1.1
—
—
—
0
0
6
36
1.67
0.56
1.0
1.2
—
—
—
0
0
16
115
1.39
0.56
1.9
1.7
—
—
—
0
0
120
1080
1.12
0.55
5.0
9.2
8.0
8.4
mmol/l
0.30
113
1036
1083
11066
0.95
0.55
3.2
3.1
49.9
46.9
u/l
0.53
1033
10572
8
125
0.64
0.54
1.0
1.2
—
—
—
0
0
37
304
1.22
0.53
2.2
1.9
—
—
—
0
0
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
40
332
1.21
0.52
3.5
3.1
0.3
0.3
u/ml
0.04
24
173
6
100
0.60
0.51
2.5
1.7
—
—
—
0
0
59
510
1.16
0.50
1.5
1.5
—
—
—
0
0
78
689
1.14
0.50
1.8
2.3
2510.4
4632.5
u/l
0.61
29
263
10
67
1.50
0.49
1.5
1.8
—
—
—
0
0
10
67
1.50
0.49
1.5
1.8
—
—
—
0
0
118
1071
1.11
0.49
1.1
1.2
74.6
142.4
iu/ml
1.36
41
427
17
128
1.33
0.47
1.3
1.2
0.1
0.3
u/ml
—
6
55
7
47
1.49
0.47
1.0
2.0
—
—
—
0
0
386
3683
1.06
0.47
1.6
1.6
1.4
1.5
mmol/l
1.06
335
3184
22
173
1.28
0.46
1.3
1.6
—
—
—
0
0
7
49
1.43
0.46
1.3
2.0
—
—
—
0
0
242
2570
0.93
0.45
1.9
1.9
1.5
1.4
%
0.82
220
2330
7
50
1.40
0.45
1.3
1.4
—
—
—
0
0
7
50
1.40
0.45
1.3
1.4
—
—
—
0
0
40
469
0.85
0.44
1.7
1.6
—
—
—
0
0
18
139
1.30
0.43
1.0
1.1
—
—
—
0
0
19
148
1.29
0.43
3.0
1.9
—
—
—
0
0
10
140
0.71
0.43
1.1
1.6
0.8
1.0
g/l
—
10
140
8
56
1.43
0.42
1.3
1.4
—
—
—
0
0
8
56
1.43
0.42
1.0
1.1
—
—
—
0
0
12
87
1.38
0.42
1.4
1.2
—
—
—
0
0
33
277
1.19
0.41
1.1
1.0
2.9
2.4
u/ml
—
6
143
0
17
0.00
0.40
0.0
1.3
—
—
—
0
0
8
60
1.33
0.40
1.9
1.4
9.0
8.4
ug/l
—
8
60
0
18
0.00
0.40
0.0
1.0
—
2.0
—
0
10
7
102
0.69
0.39
1.3
1.5
—
—
—
0
0
173
1619
1.08
0.39
2.2
2.3
14.2
13.8
nmol/l
0.28
154
1489
283
2696
1.06
0.38
2.5
2.5
0.7
0.7
ug/l
0.30
183
1477
12
89
1.35
0.38
2.2
1.6
—
1357281.3
—
0
8
107
987
1.09
0.35
2.1
2.0
—
—
—
0
0
407
3933
1.05
0.32
3.1
3.4
8.4
8.5
mmol/l
0.13
363
3400
76
694
1.10
0.32
7.5
9.1
25.3
24.6
mmol/l
1.37
68
647
84
772
1.09
0.31
1.6
1.9
34.3
36.6
nmol/l
0.61
84
754
41
362
1.14
0.30
1.3
1.5
—
17.1
—
0
7
80
735
1.09
0.30
1.5
1.8
—
—
—
0
0
48
535
0.89
0.29
1.4
1.4
—
—
—
0
0
8
106
0.75
0.29
1.1
1.3
—
—
—
0
0
15
121
1.24
0.28
1.7
1.3
—
—
—
0
0
10
76
1.32
0.28
1.0
1.1
100.1
202.5
iu/ml
—
10
76
10
76
1.32
0.28
1.5
1.7
—
—
—
0
0
16
194
0.82
0.27
1.2
1.1
—
—
—
0
0
15
122
1.23
0.27
1.7
1.3
—
—
—
0
0
19
224
0.85
0.25
2.5
2.7
1.3
1.6
mmol/l
0.71
19
218
9
77
1.17
0.24
5.2
2.5
26.2
438.9
ug/l
—
9
67
16
133
1.20
0.24
3.4
2.0
—
—
—
0
0
23
265
0.87
0.24
1.0
1.0
0.0
0.4
u/ml
—
6
59
133
1262
1.06
0.23
2.2
2.0
—
—
—
0
0
26
228
1.14
0.22
1.9
2.3
18.0
17.0
%
0.43
14
115
7
92
0.76
0.22
1.1
2.0
—
—
—
0
0
24
210
1.14
0.21
1.1
1.5
130.5
203.4
pmol/l
—
6
69
5
42
1.19
0.21
1.0
2.1
54.3
48.3
ug/l
—
5
42
0
11
0.00
0.21
0.0
1.0
—
21.0
—
0
6
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
83.3
—
0
10
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
31
277
1.12
0.21
1.4
1.2
4.1
5.2
u/ml
0.14
12
88
0
12
0.00
0.21
0.0
5.0
—
485.3
—
0
12
(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
11
89
1.24
0.21
1.0
1.1
—
—
—
0
0
0
13
0.00
0.21
0.0
1.1
—
—
—
0
0
37
335
1.11
0.20
1.3
1.5
92.3
116.1
u/ml
0.81
11
63
1418
14271
0.97
0.20
3.7
3.6
1.3
1.4
mmol/l
1.40
1352
13498
11
134
0.82
0.20
1.8
1.7
—
—
—
0
0
27
303
0.89
0.20
1.0
1.0
2.5
3.4
u/ml
0.30
12
114
25
282
0.88
0.20
1.0
1.1
4.6
4.6
u/ml
0.01
13
110
0
14
0.00
0.20
0.0
1.0
—
—
—
0
0
0
14
0.00
0.20
0.0
1.2
—
—
—
0
0
9
111
0.81
0.20
1.6
2.3
—
—
—
0
0
9
114
0.79
0.20
2.8
4.1
—
—
—
0
0
42
384
1.10
0.20
1.2
1.2
—
—
—
0
0
79
744
1.06
0.19
1.4
1.6
260.2
280.4
mu/l
0.16
70
687
6
53
1.13
0.18
1.0
1.0
—
—
—
0
0
20
175
1.14
0.18
1.0
1.1
—
—
—
0
0
25
279
0.89
0.18
1.5
1.5
—
—
—
0
0
45
416
1.08
0.17
1.6
2.3
255.4
285.0
ug/l
0.07
37
391
1506
14989
1.03
0.17
4.2
4.2
2.9
2.9
mmol/l
1.74
1437
14178
24
267
0.90
0.16
1.2
1.1
—
9.4
—
0
25
11
92
1.20
0.16
1.5
1.7
—
—
—
0
0
8
72
1.11
0.16
1.0
1.1
—
—
—
0
0
24
216
1.11
0.15
3.1
3.5
3.6
60.0
u/ml
0.50
24
202
54
575
0.94
0.15
4.4
3.9
24.2
24.3
mmol/l
0.08
46
522
16
140
1.14
0.15
1.3
2.0
—
—
—
0
0
9
81
1.11
0.15
3.8
3.4
894.0
819.4
u/ml
—
9
81
1491
14845
1.03
0.15
4.0
4.0
4.7
4.8
mmol/l
1.38
1430
14126
8
98
0.82
0.13
2.3
1.7
—
—
—
0
0
13
113
1.15
0.13
3.4
2.5
—
—
—
0
0
12
138
0.87
0.13
1.1
1.4
1.5
1.4
nmol/l
0.17
12
128
31
287
1.08
0.12
1.2
1.1
—
—
—
0
0
1484
14786
1.02
0.11
3.9
3.9
1.4
1.4
mmol/l
1.62
1417
14017
95
916
1.04
0.11
2.2
3.4
4.7
4.6
pmol/l
0.11
86
826
28
301
0.93
0.11
2.1
2.4
73.8
136.2
ug/min
1.05
17
183
25
233
1.07
0.09
1.5
1.3
—
—
—
0
0
25
233
1.07
0.09
1.5
1.3
—
—
—
0
0
5
61
0.82
0.08
1.0
1.1
—
—
—
0
0
7
65
1.08
0.08
1.1
1.2
—
—
—
0
0
7
66
1.06
0.08
2.4
2.1
—
—
—
0
0
11
122
0.90
0.07
1.8
2.3
4.1
4.0
mmol/l
0.53
11
122
11
122
0.90
0.07
1.8
2.3
106.0
105.7
mmol/l
0.08
11
122
103
1053
0.98
0.06
3.7
3.8
1.8
2.0
mmol/l
0.27
85
846
20
213
0.94
0.06
1.3
1.6
—
—
—
0
0
98
959
1.02
0.06
1.4
1.3
23.6
25.8
iu/l
0.28
87
817
17
182
0.93
0.05
1.3
1.7
—
—
—
0
0
29
277
1.05
0.05
2.0
2.6
24.7
24.7
mmol/l
0.01
23
250
43
416
1.03
0.05
2.8
2.9
1.3
1.4
mg/l
0.67
43
390
13
120
1.08
0.05
1.1
1.2
—
—
—
0
0
14
131
1.07
0.03
2.1
1.9
—
—
—
0
0
38
391
0.97
0.03
1.0
1.1
3.0
1.9
u/ml
0.16
16
154
36
370
0.97
0.03
1.2
1.2
330.4
264.0
u/ml
0.53
22
231
12
112
1.07
0.03
1.2
3.8
—
—
—
0
0
13
122
1.07
0.02
2.7
2.6
—
—
—
0
0
364
3623
1.01
0.02
3.3
3.3
21.7
21.0
%
0.39
164
1347
361
3595
1.01
0.02
3.8
4.1
6.5
9.9
mg/mmol
1.63
237
2374
20
208
0.96
0.02
1.2
1.1
102.7
97.4
%
0.39
20
198
35
342
1.02
0.01
1.6
1.7
—
—
—
0
0
53
523
1.01
0.01
1.4
1.5
—
—
—
0
0
16
154
1.04
0.00
1.8
1.8
20.0
19.7
nmol/l
0.05
16
145
11
105
1.05
0.00
1.9
1.2
—
—
—
0
0
27
269
1.00
0.00
3.0
3.1
18.0
24.4
mg/l
0.50
19
165
20
196
1.02
0.00
1.0
1.1
—
—
—
0
0
19
188
1.01
0.00
1.0
1.1
—
—
—
0
0
28
278
1.01
0.00
1.3
1.2
5.2
4.4
u/ml
—
10
116
14
137
1.02
0.00
1.1
1.1
—
—
—
0
0
62
617
1.01
0.00
1.3
1.4
7.8
8.3
u/l
0.13
55
511
0
8
0.00
0.00
0.0
1.6
—
—
—
0
0
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
0.00
0.0
1.7
—
2.1
—
0
6
0
5
0.00
0.00
0.0
12.8
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
0.00
0.0
2.8
—
—
—
0
0
0
5
0.00
0.00
0.0
3.8
—
7.6
—
0
5
0
6
0.00
0.00
0.0
1.0
—
8.2
—
0
6
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
6
60
1.00
0.00
5.7
3.3
—
—
—
0
0
0
7
0.00
0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
0
7
0.00
0.00
0.0
4.3
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
5
59
0.85
0.00
1.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
7
77
0.91
0.00
1.0
1.1
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint M13_ANKYLOSPON_STRICT and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| M13_ANKYLOSPON_STRICT | 0.709 [0.53, 0.95] | 0.019 |
| Birth year | 0.993 [0.98, 1.0] | 0.138 |
During the follow-up period (1.1.1998 — 31.12.2019), 51 out of 2980 females with M13_ANKYLOSPON_STRICT died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| M13_ANKYLOSPON_STRICT | 0.829 [0.71, 0.96] | 0.015 |
| Birth year | 0.988 [0.98, 1.0] | 0.014 |
During the follow-up period (1.1.1998 — 31.12.2019), 218 out of 4769 males with M13_ANKYLOSPON_STRICT died.
Mortality risk
Mortality risk for people of age
years, who have M13_ANKYLOSPON_STRICT.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.071% | 0.139% |
| 5 | 0.43% | 1.001% |
| 10 | 1.008% | 2.594% |
| 15 | 1.862% | 4.725% |
| 20 | 3.295% | 8.268% |
Relationships between endpoints
↥Index endpoint: M13_ANKYLOSPON_STRICT – Ankylosing spondylitis, strict definition
GWS hits: 12
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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