ankylosing spondylitis: An autoimmune chronic inflammatory disorder characterized by inflammation in the vertebral joints of the spine and sacroiliac joints. It predominantly affects young males. Patients present with stiffness and pain in the spine.
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
519972 |
1. Apply sex-specific ruleNone |
519972 |
2. Check conditions
|
3772 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
1 out of 7 registries used, show all original rules. |
1798 |
4. Check minimum number of eventsNone |
1798 |
5. Include endpointsNone |
1798 |
6. Filter based on genotype QC (FinnGen only) |
1727 |
Control definitions (FinnGen only)
- Control conditions
- not M13_ANKYLOSPON_ICD10
Extra metadata
- Level in the ICD hierarchy
- C
- First used in FinnGen datafreeze
- DF3
Similar endpoints
↥List of similar endpoints to
Ankylosing spondylitis, strict definition
based on the number of shared cases.
Similar with more cases:
- Ankylosing spondylitis, ICD10
- Ankylosing spondylitis
- Spondylopathies (FG)
- Spondyloarthritis
- Autoimmune diseases related-to ILD
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 8672 | 3328 | 5319 |
| Only index persons | 8532 | 3302 | 5230 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.13 | 0.10 | 0.15 |
| Only index persons | 0.17 | 0.12 | 0.20 |
| Median age at first event (years) | |||
| Whole population | 37.75 | 38.28 | 37.43 |
| Only index persons | 37.70 | 38.29 | 37.33 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 1727 | 800 | 927 |
| Unadjusted period prevalence (%) | 0.36 | 0.28 | 0.42 |
| Median age at first event (years) | 39.36 | 38.37 | 40.21 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 1798
- Matched controls
- 17980
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
313
Kela drug reimbursment
Abatacept, adalimumab, anakinra, certolizumab pegol, etanercept, golimumab, infliximab, ixekizumab, sarilumab, secukinumab, tocilizumab and ustekinumab (rheumatoid diseases)
142.3
307.7
1113
203
L88
ICPC
Rheumatoid/seropositive arthritis
28.5
307.7
489
233
M46.9
ICD-10 Finland
Inflammatory spondylopathy, unspecified
70.7
307.7
344
60
H20.0
ICD-10 Finland
Acute and subacute iridocyclitis
32.6
307.7
631
293
TNX10
NOMESCO Finland
Arthrocentesis, unspecified region, unspecified region
13.6
307.7
524
527
S01BA04
ATC
prednisolone; ophthalmic
25.7
307.7
232
103
L04AC10
ATC
secukinumab; parenteral
73.5
307.7
179
27
NK4XE
NOMESCO Finland
Joint ultrasound examination not elsewhere classified
20.9
307.7
708
543
M45
ICD-10 Finland
Ankylosing spondylitis
+∞
307.7
1798
30
202
Kela drug reimbursment
Connective tissue diseases, rheumatoid arthritis and comparable disease
7786.7
307.7
1794
863
L04AB01
ATC
etanercept; parenteral
88.8
307.7
529
84
A07EC01
ATC
sulfasalazine; oral, rectal
339.5
307.7
1661
620
NA6BG
NOMESCO Finland
Sacro-iliac joint MRI examination with high intensity magnet
44.0
307.7
375
107
281
Kela drug reimbursment
Abatacept, adalimumab, anakinra, certolizumab pegol, etanercept, golimumab, infliximab, ixekizumab, sarilumab, secukinumab and tocilizumab
140.2
307.7
1085
193
L04AB06
ATC
golimumab; parenteral
114.1
307.7
379
42
L04AX03
ATC
methotrexate; systemic
27.5
307.7
1041
856
L04AB04
ATC
adalimumab; parenteral
62.4
307.7
671
170
M46.1
ICD-10 Finland
Sacroiliitis, not elsewhere classified
67.4
307.7
396
75
L01BA01
ATC
methotrexate; systemic
28.8
307.7
432
195
S01BA01
ATC
dexamethasone; ophthalmic
14.0
259.5
252
207
L04AB05
ATC
certolizumab pegol; parenteral
78.6
257.8
138
19
S01CA02
ATC
prednisolone and antiinfectives; ophthalmic
37.9
245.7
153
44
H20.1
ICD-10 Finland
Chronic iridocyclitis
31.1
240.2
159
56
L04AA13
ATC
[U] leflunomide
17.0
229.8
197
129
L04AA11
ATC
[U] etanercept
81.8
216.1
115
15
H02AB06
ATC
prednisolone; systemic
4.8
215.4
1248
5793
M01AH01
ATC
celecoxib; oral
5.1
211.5
580
1528
NF1AE
NOMESCO Finland
Hip joint ultrasound examination
14.9
197.9
182
135
WZA10
NOMESCO Finland
Extensive medical or dental certificate
18.1
195.4
161
97
S01FA04
ATC
cyclopentolate; ophthalmic
23.3
185.4
136
63
H22.1*M45
ICD-10 Finland
Iridocyclitis in ankylosing spondylitis
+∞
169.5
160
*
S01FA02
ATC
scopolamine; ophthalmic
31.9
165.4
108
36
NA3BG
NOMESCO Finland
Lumbar spine MRI examination with high intensity magnet
5.2
164.2
398
929
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
3.8
153.4
693
2563
M01AC06
ATC
meloxicam; systemic, rectal
3.5
149.7
918
4115
NA6CG
NOMESCO Finland
Sacro-iliac joint extensive MRI examination with high intensity magnet
41.1
148.3
90
23
P01BA02
ATC
hydroxychloroquine; oral
5.7
145.5
305
623
7200A
ICD-9 Finland
Ankylosing spondylitis and other inflammatory spondylopathies, Ankylosing spondylitis
1283.9
124.5
120
*
GD1AA
NOMESCO Finland
Thorax X-ray examination
3.1
120.8
962
4863
M01AH05
ATC
etoricoxib; oral
3.8
118.0
1450
9365
H20.9
ICD-10 Finland
Iridocyclitis, unspecified
14.7
114.2
104
75
L04AA17
ATC
[U] adalimumab
53.5
108.4
62
12
H02AB07
ATC
prednisone; oral
3.9
106.5
371
1121
NA6AA
NOMESCO Finland
Sacro-iliac joint X-ray examination
45.8
104.9
62
14
NA2AA
NOMESCO Finland
Thoracal spine X-ray examination without contrast
9.6
103.3
125
139
NA2BG
NOMESCO Finland
Thoracal spine MRI examination with high intensity magnet
8.3
97.1
132
170
M05.8
ICD-10 Finland
Other seropositive rheumatoid arthritis
6.1
96.4
176
312
NA1EA
NOMESCO Finland
Cervical spine X-ray examination with flexion
14.2
95.1
88
65
TNX00
NOMESCO Finland
Puncture and needle biopsy of soft tissue, unspecified region
10.0
91.8
107
113
M13.9
ICD-10 Finland
Arthritis, unspecified
4.3
87.7
248
639
N02AX02
ATC
tramadol; systemic, rectal
2.6
84.5
914
5127
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
4.1
84.2
263
729
XX9XE
NOMESCO Finland
Other ultrasound examination
20.7
83.9
64
32
M01CB01
ATC
sodium aurothiomalate; parenteral
15.8
77.1
67
44
M05BA04
ATC
alendronic acid; oral
5.3
72.0
151
303
M01AH02
ATC
rofecoxib; oral
3.5
70.9
278
895
TNG10
NOMESCO Finland
Puncture of knee
12.1
70.8
72
62
ZX120
NOMESCO Finland
Intravenous
3.7
70.7
247
737
NF1AA
NOMESCO Finland
Hip X-ray examination
4.5
70.2
184
445
NA1AA
NOMESCO Finland
Cervical spine X-ray examination without contrast
5.6
68.0
134
254
ZX140
NOMESCO Finland
Intra articular
14.1
64.9
60
44
L04AA01
ATC
[U] ciclosporin
11.2
64.6
69
64
NA3CG
NOMESCO Finland
Lumbar spine extensive MRI examination with high intensity magnet
5.2
63.9
138
284
M01AX01
ATC
nabumetone; oral
5.4
62.2
129
256
4AB02, ,
NOMESCO Finland
23.1
61.7
45
20
M46.8
ICD-10 Finland
Other specified inflammatory spondylopathies
213.9
60.5
62
*
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
2.3
59.6
733
4176
NA1BA
NOMESCO Finland
Cervical spine extensive X-ray examination without contrast
15.3
59.0
52
35
A02BC02
ATC
pantoprazole; systemic
2.3
56.9
1267
9110
M02.9
ICD-10 Finland
Reactive arthropathy, unspecified
7.2
56.2
85
123
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
2.1
54.1
936
6040
L04AX01
ATC
azathioprine; systemic
4.3
53.3
144
355
71240
ICD-8 Finland
Rheumatoid arthritis and allied conditions, Spondylitis ankylopoietica
144.4
53.1
56
*
R4110
NOMESCO Finland
Physiotherapy
2.3
50.7
548
2922
M01AB01
ATC
indometacin; systemic, rectal
4.0
50.7
154
414
M06.9
ICD-10 Finland
Rheumatoid arthritis, unspecified
6.1
50.4
90
155
M01AE02
ATC
naproxen; oral, rectal
2.1
49.6
1133
8018
ZY020
NOMESCO Finland
Telephone, letter or other consultation without direct patient contact
3.7
49.2
169
495
L04AB02
ATC
infliximab; parenteral
11.9
49.1
50
43
H15.1
ICD-10 Finland
Episcleritis
7.4
48.9
72
101
UJF32
NOMESCO Finland
Coloscopy
2.3
47.4
467
2387
A02BC03
ATC
lansoprazole; oral
2.2
46.9
530
2863
M01AX17
ATC
nimesulide; oral
2.3
45.7
434
2180
M01AB55
ATC
diclofenac, combinations; oral
3.9
45.6
140
379
208
Kela drug reimbursment
Ulcerative colitis and Crohn's disease
3.6
45.2
161
482
NA1BG
NOMESCO Finland
Cervical spine MRI examination with high intensity magnet
3.6
43.9
157
471
Z01.0
ICD-10 Finland
Examination of eyes and vision
2.4
43.8
361
1702
4AA12, ,
NOMESCO Finland
17.5
43.7
36
21
M54.9
ICD-10 Finland
Dorsalgia, unspecified
2.6
43.5
297
1283
M01AE03
ATC
ketoprofen; systemic, rectal
2.0
42.7
670
4070
NK5AT
NOMESCO Finland
Joint injection with ultrasound guidance not elsewhere classified
11.5
42.3
44
39
NF2AT
NOMESCO Finland
Injection to hip joint with ultrasound guidance
15.1
41.7
37
25
K50.0
ICD-10 Finland
Crohn disease of small intestine
6.1
41.7
73
123
UJF30
NOMESCO Finland
Ileoscopy through colon
2.7
39.5
229
909
NH3EA
NOMESCO Finland
Feet X-ray examination with load
6.1
39.5
69
116
K50.8
ICD-10 Finland
Other Crohn disease
5.7
39.3
74
134
M03BX02
ATC
tizanidine; oral
2.0
38.7
1258
9668
Z3229
NOMESCO Finland
Other healthcare associate professional
3.0
37.4
174
613
NB1AE
NOMESCO Finland
Shoulder ultrasound examination
6.0
37.2
67
116
H04.10
ICD-10 Finland
Dry eye syndrome
2.6
37.1
240
1006
S01BC03
ATC
diclofenac; ophthalmic
5.7
37.1
70
127
ZXX01
NOMESCO Finland
Extent of proceudre, 1 unit
10.7
36.7
40
38
H57.1
ICD-10 Finland
Ocular pain
3.7
36.3
118
332
A07EC02
ATC
mesalazine; oral, rectal
3.1
36.1
158
537
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
2.7
35.7
203
797
NG1AE
NOMESCO Finland
Knee joint ultrasound exmination
7.8
35.4
49
64
M01AB05
ATC
diclofenac; systemic, rectal
2.0
35.2
1276
10001
NE1AA
NOMESCO Finland
Pelvis X-ray examination
3.5
34.9
126
380
Z3226
NOMESCO Finland
Physiotherapist
2.2
34.6
343
1734
NE1CG
NOMESCO Finland
Pelvic, hip and femur extensive MRI examination with high intensity magnet
5.5
34.4
67
125
TNG11
NOMESCO Finland
Injection of diagnostic or therapeutic substance in knee
8.4
34.3
45
55
H40.5
ICD-10 Finland
Glaucoma secondary to other eye disorders
10.5
34.3
38
37
A07EA06
ATC
budesonide; oral, local oral
3.8
34.1
109
303
NG1DA
NOMESCO Finland
X-ray of knees
6.2
33.7
58
96
O99.89
ICD-10 Finland
Other specified diseases and conditions complicating pregnancy, childbirth and the puerperium
5.2
33.6
70
139
M79.0
ICD-10 Finland
Rheumatism, unspecified
4.4
33.3
86
204
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.8
32.9
793
5430
H20
ICD-10 Finland
Iridocyclitis
9.7
32.5
38
40
M06.0
ICD-10 Finland
Seronegative rheumatoid arthritis
4.7
32.4
76
167
NA2CG
NOMESCO Finland
Thoracal spine extensive MRI examination with high intensity magnet
8.4
32.2
42
51
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.9
31.2
473
2785
H02AB04
ATC
methylprednisolone; systemic
2.3
30.7
277
1342
M07.3*L40.5
ICD-10 Finland
Other psoriatic arthropathies
4.6
29.8
71
158
H22.1
ICD-10 Finland
Iridocyclitis in other diseases classified elsewhere
157.6
29.7
31
*
NH1AE
NOMESCO Finland
Ankle joint ultrasound examination
8.9
29.0
36
41
K50.9
ICD-10 Finland
Crohn disease, unspecified
5.2
28.8
60
119
N02AJ06
ATC
codeine and paracetamol; systemic
1.7
28.3
818
5825
NA1CG
NOMESCO Finland
Cervical spine extensive MRI examination with high intensity magnet
4.8
27.9
63
134
NG1AA
NOMESCO Finland
Knee X-ray examination without contrast
2.4
27.8
207
921
M46.0
ICD-10 Finland
Spinal enthesopathy
78.9
27.8
31
*
3640A
ICD-9 Finland
Disorders of iris and ciliary body, Acute and subacute iridocyclitis
285.8
27.8
28
*
N02BE01
ATC
paracetamol; systemic, rectal
2.2
26.8
1562
13566
M35.7
ICD-10 Finland
Hypermobility syndrome
5.6
26.6
51
94
TNH11
NOMESCO Finland
Injection of diagnostic or therapeutic substance in ankle joint or foot joint
6.6
26.5
43
67
M03BC01
ATC
orphenadrine (citrate); systemic
1.8
26.2
484
3011
S01BA07
ATC
fluorometholone; ophthalmic
5.1
25.7
54
108
TND11
NOMESCO Finland
Injection of diagnostic or therapeutic substance in joint, wrist or hand
6.0
25.3
45
77
NH3AA
NOMESCO Finland
Foot and toes X-ray examination
2.5
25.1
175
755
A02BC05
ATC
esomeprazole; systemic
1.7
25.0
695
4850
M54.5
ICD-10 Finland
Low back pain
1.7
24.8
688
4795
NK6QA
NOMESCO Finland
Measurement of bone density from two or more locations with X-ray
2.9
24.8
120
431
XCW99
NOMESCO Finland
Other investigative procedure of eye
2.4
24.7
178
780
ND2AA
NOMESCO Finland
Hand and fingers X-ray examination
2.3
24.2
190
864
M13.8
ICD-10 Finland
Other specified arthritis
6.7
23.9
38
58
M01AB08
ATC
etodolac; oral
2.6
23.8
146
592
NF1DA
NOMESCO Finland
X-ray of hips
5.5
23.6
46
86
L04AC13
ATC
ixekizumab; parenteral
27.1
23.6
32
12
UJF92
NOMESCO Finland
Capsular endoscopy
4.3
23.4
61
146
RK220, ,
NOMESCO Finland
20.4
23.0
34
17
S01ED01
ATC
timolol; ophthalmic
4.5
23.0
56
127
WZB00
NOMESCO Finland
Telephone prescription or other care instructions
1.7
22.8
581
3939
NB1AA
NOMESCO Finland
Shoulder X-ray examination without contrast
2.6
22.4
133
531
M25.5
ICD-10 Finland
Pain in joint
1.7
22.3
607
4182
298, ,
Kela drug reimbursment
21.7
22.1
32
15
RF120, ,
NOMESCO Finland
6.9
22.1
34
50
3029
Kela drug reimbursment
Upadacitinib
20.3
21.7
32
16
M16.7
ICD-10 Finland
Other secondary coxarthrosis
7.8
21.7
30
39
K51.9
ICD-10 Finland
Ulcerative colitis, unspecified
3.2
21.6
88
286
M54.6
ICD-10 Finland
Pain in thoracic spine
2.3
21.4
168
763
K52.9
ICD-10 Finland
Noninfective gastroenteritis and colitis, unspecified
3.2
21.4
86
277
L99
ICPC
Musculoskeletal disease other
4.4
21.4
54
126
S01CA01
ATC
dexamethasone and antiinfectives; ophthalmic
1.7
21.4
454
2918
L02
ICPC
Back symptom/complaint
2.2
21.2
202
994
K51.5
ICD-10 Finland
Left sided colitis
3.2
20.8
86
282
J01DB01
ATC
cefalexin; oral
1.8
19.7
1488
13056
TCF00
NOMESCO Finland
Subconjunctival therapeutic injection
24.9
19.5
27
11
M03BC51
ATC
orphenadrine, combinations; systemic
1.7
19.3
508
3446
K50.1
ICD-10 Finland
Crohn disease of large intestine
4.8
19.2
43
91
L84
ICPC
Back syndrome without radiat pain
2.7
19.2
103
391
M01AC01
ATC
piroxicam; systemic, rectal
2.1
19.1
207
1068
M54.8
ICD-10 Finland
Other dorsalgia
2.8
18.5
97
363
SFA10
NOMESCO Finland
One-surface restoration
1.6
18.5
1016
8166
RF410, ,
NOMESCO Finland
5.3
18.5
37
71
SAA02
NOMESCO Finland
Basic examination of mouth
1.6
18.4
1244
10481
NGF15
NOMESCO Finland
Total synovectomy of knee, arthroscopic
5.2
18.4
38
75
SPAT1249
SPAT
Treatment-related counselling outside office
1.6
18.4
627
4521
L04AD01
ATC
ciclosporin; systemic
4.0
18.4
53
137
M07.4*K50.9
ICD-10 Finland
Arthropathy in Crohn's disease [regional enteritis]
25.3
18.2
25
10
RF420, ,
NOMESCO Finland
5.0
18.1
39
80
H26.3
ICD-10 Finland
Drug-induced cataract
7.7
17.8
25
33
M01AE52
ATC
naproxen and esomeprazole; oral
3.2
17.8
73
238
L04AA44
ATC
[U] upadacitinib
18.3
17.8
27
15
ND2BA
NOMESCO Finland
Hand and fingers extensive X-ray examination
3.7
17.6
56
155
WZC00
NOMESCO Finland
Treatment plan or consultation
1.6
17.3
597
4302
NA7CG
NOMESCO Finland
Spine and spinal cord extensive MRI examination with high intensity magnet
4.8
17.3
39
83
RK210, ,
NOMESCO Finland
21.1
17.3
25
12
M07.2*L40.5
ICD-10 Finland
Psoriatic spondylitis
42.4
17.3
21
5
K02.1
ICD-10 Finland
Caries of dentine
1.6
17.2
1127
9349
K57.3
ICD-10 Finland
Diverticular disease of large intestine without perforation or abscess
1.9
17.1
223
1228
N03AX16
ATC
[U] pregabalin
1.7
17.1
377
2431
WZC30
NOMESCO Finland
Teaching
1.8
16.7
262
1529
SFA20
NOMESCO Finland
Two-surface restoration
1.5
16.7
1110
9210
SPAT1325
SPAT
Vaccination
1.6
16.3
426
2865
Z50.1
ICD-10 Finland
Other physical therapy
2.6
16.1
92
361
Z3231
NOMESCO Finland
Registered nurse
1.6
15.9
425
2873
A02BC01
ATC
omeprazole; systemic
1.7
15.8
390
2583
326
Kela drug reimbursment
Adalimumab, golimumab, infliximab and ustekinumab (intestinal diseases)
4.3
15.8
41
98
T84.0
ICD-10 Finland
Mechanical complication of internal joint prosthesis
3.9
15.8
46
120
N06AA09
ATC
amitriptyline; systemic
2.1
15.7
146
710
M05BB03
ATC
alendronic acid and colecalciferol; oral
5.3
15.6
31
59
J01MA02
ATC
ciprofloxacin; systemic
1.5
15.5
585
4282
J01CA04
ATC
amoxicillin; systemic
1.7
15.4
1454
12919
R2110
NOMESCO Finland
Giving the first information
2.2
15.4
127
588
R2130
NOMESCO Finland
Counselling and guidance which enhance independent living
2.2
15.3
137
656
TPH04
NOMESCO Finland
Cathetrisation of vein
1.7
15.1
332
2131
36400
ICD-8 Finland
Iritis, Iridocyclitis acuta
23.6
15.1
21
9
M51.3
ICD-10 Finland
Other specified intervertebral disc degeneration
2.1
15.1
159
811
SPAT1253
SPAT
Initiation, adjustment, discontinuation or repetition of medication
1.6
15.0
444
3072
Z01.2
ICD-10 Finland
Dental examination
1.5
14.8
789
6188
SPAT1256
SPAT
Intramuscular and subcutaneous injection
1.5
14.8
598
4430
S01ED51
ATC
timolol, combinations; ophthalmic
2.6
14.8
90
364
EB1SA
NOMESCO Finland
Dental X-ray, bite-wing X-ray on one side of the mouth
1.5
14.8
989
8119
NH3DA
NOMESCO Finland
Bilateral foot X-ray examination
3.9
14.6
43
113
M06.8
ICD-10 Finland
Other specified rheumatoid arthritis
6.6
14.5
23
35
WZA90
NOMESCO Finland
Other medical or dental certificate
1.6
14.3
404
2757
M81.9
ICD-10 Finland
Osteoporosis, unspecified
3.4
14.3
50
148
M54.0
ICD-10 Finland
Panniculitis affecting regions of neck and back
4.1
14.3
39
97
H02AB08
ATC
triamcinolone; systemic
22.5
14.2
20
9
M07.5*K51.9
ICD-10 Finland
Arthropathy in ulcerative colitis
13.5
14.2
24
18
SAA01
NOMESCO Finland
Simple examination of mouth
1.5
14.2
1315
11487
Z2221
NOMESCO Finland
Medical doctor
1.6
14.0
448
3145
NE1BG
NOMESCO Finland
Pelvic, hip and femur MRI examination with high intensity magnet
3.0
14.0
61
207
N06AX21
ATC
duloxetine; oral
1.8
13.8
220
1288
M05BA07
ATC
risedronic acid; oral
4.5
13.8
33
74
RK250, ,
NOMESCO Finland
11.5
13.8
25
22
F01
ICPC
Eye pain
3.0
13.8
62
214
M02.1
ICD-10 Finland
Postdysenteric arthropathy
20.2
13.8
20
10
N03AX12
ATC
[U] gabapentin; oral
1.7
13.8
268
1662
K51.3
ICD-10 Finland
Ulcerative (chronic) rectosigmoiditis
3.3
13.7
51
157
M02AA07
ATC
piroxicam; topical
1.5
13.7
507
3674
RS221, ,
NOMESCO Finland
4.2
13.7
36
87
NA7DG
NOMESCO Finland
Spine and spinal cord very extensive MRI examination with high intensity magnet
4.6
13.6
32
71
S01FA06
ATC
tropicamide; ophthalmic
34.3
13.5
17
5
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.5
13.5
595
4473
TNF11
NOMESCO Finland
Injection of diagnostic or therapeutic substance in hip joint
25.9
13.4
18
7
M01CB03
ATC
auranofin; oral
10.5
13.2
25
24
ZXX02
NOMESCO Finland
Extent of procedure, 2 units
4.3
13.2
34
81
D50.9
ICD-10 Finland
Iron deficiency anaemia, unspecified
2.3
13.1
102
461
K07.65
ICD-10 Finland
Temporomandibular joint-pain-dysfunction syndrome
5.1
12.9
27
54
L34
ICPC
Musculoskeletal, Blood test
22.7
12.9
18
8
M13.0
ICD-10 Finland
Polyarthritis, unspecified
4.5
12.9
31
70
M08.1
ICD-10 Finland
Juvenile ankylosing spondylitis
50.4
12.8
15
*
H26.2
ICD-10 Finland
Complicated cataract
4.4
12.6
31
71
NA6BM
NOMESCO Finland
Sacro-iliac joint MRI examination with 3 Tesla magnet
32.3
12.6
16
5
D07AC01
ATC
betamethasone; topical
1.5
12.6
569
4286
L04AF03
ATC
upadacitinib; oral
17.4
12.5
19
11
M79.7
ICD-10 Finland
Fibromyalgia
2.6
12.5
70
272
S01EC01
ATC
acetazolamide; systemic
3.7
12.4
38
103
JF1CG
NOMESCO Finland
Extensive MRI of small bowel
5.2
12.2
25
49
L04AC05
ATC
ustekinumab; parenteral
6.1
12.1
21
35
M02.8
ICD-10 Finland
Other reactive arthropathies
6.1
12.1
21
35
K07.60
ICD-10 Finland
Snapping jaw
2.2
12.1
105
498
A02BB01
ATC
misoprostol; oral
11.8
11.8
21
18
Z71.8
ICD-10 Finland
Other specified counselling
1.5
11.7
511
3814
M01AH03
ATC
valdecoxib; oral
2.2
11.6
102
486
Z2446
NOMESCO Finland
Social worker
2.0
11.6
119
602
D64.9
ICD-10 Finland
Anaemia, unspecified
2.1
11.6
112
554
NE1BA
NOMESCO Finland
Pelvis extensive X-ray examination
5.1
11.5
24
48
RT272, ,
NOMESCO Finland
13.7
11.5
19
14
J01AA02
ATC
doxycycline; systemic
1.5
11.4
1272
11223
R42
ICD-10 Finland
Dizziness and giddiness
1.6
11.4
286
1889
M03BA52
ATC
carisoprodol, combinations excl. psycholeptics; oral
3.1
11.4
47
155
Z01.8
ICD-10 Finland
Other specified special examinations
1.5
11.3
355
2470
R06.0
ICD-10 Finland
Dyspnoea
1.5
11.3
358
2496
RT271, ,
NOMESCO Finland
35.3
11.3
14
*
H40.4
ICD-10 Finland
Glaucoma secondary to eye inflammation
35.3
11.3
14
*
N20.0
ICD-10 Finland
Calculus of kidney
3.3
11.1
42
131
K51.8
ICD-10 Finland
Other ulcerative colitis
3.4
11.1
40
121
S01FA01
ATC
atropine; ophthalmic
11.2
11.0
20
18
A06AC01
ATC
ispaghula (psylla seeds); oral
1.5
11.0
340
2355
H81.0
ICD-10 Finland
Ménière disease
3.6
10.9
35
98
Z96.1
ICD-10 Finland
Presence of intraocular lens
2.0
10.8
118
611
ND2DA
NOMESCO Finland
Bilateral hand X-ray examination
3.5
10.7
36
104
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
2.3
10.7
81
363
B01AB05
ATC
enoxaparin; parenteral
1.5
10.7
412
2991
L40.0
ICD-10 Finland
Psoriasis vulgaris
2.3
10.6
84
383
S01EA05
ATC
brimonidine; ophthalmic
3.8
10.6
32
86
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
1.9
10.6
126
671
SAA03
NOMESCO Finland
Extended examination of mouth
1.4
10.6
684
5464
SFA30
NOMESCO Finland
Three-surface restoration
1.4
10.5
732
5917
S22.0
ICD-10 Finland
Fracture of thoracic vertebra
3.7
10.5
33
91
L28
ICPC
Limited function/disability (L)
1.7
10.5
186
1120
ZXE00
NOMESCO Finland
One hour or less
1.4
10.4
590
4599
7202A
ICD-9 Finland
Ankylosing spondylitis and other inflammatory spondylopathies, Sacro-iliitis, not elsewhere classified
+∞
10.4
10
*
NAJ12
NOMESCO Finland
Posterior reduction of fracture of cervical spine
32.7
10.3
13
*
H30.2
ICD-10 Finland
Posterior cyclitis
10.7
10.3
19
18
J01.0
ICD-10 Finland
Acute maxillary sinusitis
1.5
10.3
427
3143
D06BB04
ATC
podophyllotoxin; topical
1.9
10.3
122
650
M02AA10
ATC
ketoprofen; topical
1.6
10.2
226
1445
SPAT1202
SPAT
Intra-articular injection
3.2
10.2
40
128
SPAT1263
SPAT
Sampling
1.4
10.1
621
4909
RF210, ,
NOMESCO Finland
2.7
10.1
54
206
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
1.7
10.0
200
1245
NK4AT
NOMESCO Finland
Puncture of joint with ultrasound guidance not elsewher classified
4.8
10.0
22
46
L40.5
ICD-10 Finland
Arthropathic psoriasis
3.3
10.0
37
114
7168A
ICD-9 Finland
Other and unspecified arthropathies, Other specified arthropathy
40.3
10.0
12
*
WX002
NOMESCO Finland
Sedation and analgesia
1.6
10.0
259
1723
M47.82
ICD-10 Finland
Other spondylosis, cervical region
2.4
9.9
65
273
Z04.8
ICD-10 Finland
Examination and observation for other specified reasons
1.7
9.9
208
1312
P01AB01
ATC
metronidazole; oral, rectal
1.4
9.9
621
4922
J01FF01
ATC
clindamycin; systemic
1.5
9.8
426
3156
EB1AA
NOMESCO Finland
Intraoral radiographic dental examination
1.4
9.8
965
8225
Z87.1
ICD-10 Finland
Personal history of diseases of the digestive system
1.4
9.8
712
5779
ZX114
NOMESCO Finland
Intramuscular
3.5
9.8
33
96
M07.4
ICD-10 Finland
Arthropathy in Crohn disease [regional enteritis]
55.3
9.7
11
*
NA7BG
NOMESCO Finland
Spine and spinal cord MRI examination with high intensity magnet
5.3
9.6
19
36
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
2.0
9.6
109
571
UJF45
NOMESCO Finland
Flexible sigmoidoscopy with biopsy
1.9
9.6
113
601
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
1.5
9.5
318
2234
SPAT1251
SPAT
Organisation of medication
2.7
9.4
49
184
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
1.7
9.4
185
1147
M01AA01
ATC
phenylbutazone; systemic, rectal
+∞
9.4
9
*
J99.8*M45
ICD-10 Finland
Respiratory disorders in ankylosing spondylitis
+∞
9.4
9
*
TNB11
NOMESCO Finland
Injection of diagnostic or therapeutic substance in shoulder joint
8.1
9.3
20
25
GD1DD
NOMESCO Finland
High resolution CT examination of lungs
2.3
9.3
68
300
J18.9
ICD-10 Finland
Pneumonia, unspecified
1.5
9.3
284
1958
NH3BA
NOMESCO Finland
Foot and toes extensive X-ray examination
2.4
9.2
62
264
WX290
NOMESCO Finland
Other blockage of nerve
1.4
9.2
892
7553
C10AC01
ATC
colestyramine; oral
2.7
9.2
47
175
M70.6
ICD-10 Finland
Trochanteric bursitis
1.7
9.2
158
945
R03AC02
ATC
salbutamol; inhalant
1.4
9.1
899
7627
H05BA01
ATC
calcitonin (salmon synthetic); nasal, parenteral
3.9
9.1
26
67
S12.2
ICD-10 Finland
Fracture of other specified cervical vertebra
4.3
9.1
23
54
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.4
9.0
891
7557
M46
ICD-10 Finland
Other inflammatory spondylopathies
36.9
9.0
11
*
L03
ICPC
Low back symptom/complaint
1.4
9.0
420
3149
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
1.4
9.0
936
8005
K51.1
ICD-10 Finland
Ulcerative (chronic) ileocolitis
3.6
9.0
29
82
M66.0
ICD-10 Finland
Rupture of popliteal cyst
4.2
8.9
23
55
N06CA01
ATC
amitriptyline and psycholeptics; systemic
1.8
8.9
134
770
NHG77
NOMESCO Finland
Arthroplasty of interphalangeal tarsal joint(s)
3.7
8.9
27
73
E0000UV, ,
ATC
1.4
8.7
628
5068
M01AB16
ATC
aceclofenac; oral
2.7
8.6
44
164
D07AD01
ATC
clobetasol; topical
1.5
8.5
243
1649
NFB30
NOMESCO Finland
Primary total prosthetic replacement of hip joint not using cement
2.1
8.5
81
399
A02BA02
ATC
ranitidine; systemic
1.6
8.5
233
1567
R50.9
ICD-10 Finland
Fever, unspecified
1.6
8.4
230
1547
71490
ICD-8 Finland
Other specified forms of arthritis, Arthritis postinfectiosa NUD
12.8
8.4
14
11
R1240
NOMESCO Finland
Social assessment of need and possibilities of rehabilitation
3.8
8.3
25
67
4AB0X, ,
NOMESCO Finland
+∞
8.3
8
*
F02
ICPC
Red eye
2.3
8.3
63
283
L30.9
ICD-10 Finland
Dermatitis, unspecified
1.5
8.3
307
2200
WW200
NOMESCO Finland
Immunization
2.4
8.3
54
227
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
1.8
8.2
124
713
TCA20
NOMESCO Finland
Peribulbar therapeutic injection into orbit
14.5
8.2
13
9
-44
ICPC
Preventive immunization/medic
1.9
8.1
94
497
CK2X4
NOMESCO Finland
Optical coherence tomography (OCT) of ocular fundus
1.8
8.1
116
657
N02AC04
ATC
dextropropoxyphene; oral
2.8
8.1
39
141
H11.3
ICD-10 Finland
Conjunctival haemorrhage
2.3
8.0
58
256
H02BX01
ATC
methylprednisolone, combinations; systemic
2.4
8.0
54
231
ZXE10
NOMESCO Finland
More than one and less than three hours
1.4
8.0
498
3916
EB1JA
NOMESCO Finland
Double panorama tomography of teeth and jaws or similar X-ray examination
4.3
7.9
20
47
H10.9
ICD-10 Finland
Conjunctivitis, unspecified
1.9
7.9
106
588
L01BB02
ATC
mercaptopurine; oral
3.1
7.9
32
105
R4120
NOMESCO Finland
Occupational therapy
1.9
7.9
104
575
RS222, ,
NOMESCO Finland
4.1
7.8
21
52
UJH02
NOMESCO Finland
Anoscopy
2.2
7.8
62
285
NH1AA
NOMESCO Finland
Ankle X-ray examination without contrast
1.8
7.7
107
600
S01FB01
ATC
phenylephrine; ophthalmic
45.2
7.7
9
*
O99.1
ICD-10 Finland
Other diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism complicating pregnancy, childbirth and the puerperium
6.4
7.7
19
30
G47.3
ICD-10 Finland
Sleep apnoea
1.4
7.7
390
2958
M07.3
ICD-10 Finland
Other psoriatic arthropathies
3.6
7.7
25
71
WX110
NOMESCO Finland
Infiltration anesthesia
1.3
7.7
1223
11012
A03FA01
ATC
metoclopramide; systemic, rectal
1.5
7.7
294
2119
SDA03
NOMESCO Finland
Periodontal treatment
1.3
7.7
686
5691
NA1AD
NOMESCO Finland
Cervical spine CT examination
2.1
7.7
70
340
JN3BD
NOMESCO Finland
Extensive abdominal CT
1.7
7.6
138
837
J01MA12
ATC
levofloxacin; systemic
1.5
7.6
236
1629
M05BA06
ATC
ibandronic acid; systemic
4.0
7.6
21
53
R07.0
ICD-10 Finland
Pain in throat
1.8
7.6
120
700
DM1AA
NOMESCO Finland
Paranasal sinuses X-ray examination without contrast
2.3
7.6
58
262
RT171, ,
NOMESCO Finland
11.9
7.6
13
11
1008, ,
NOMESCO Finland
25.1
7.6
10
*
ZX112
NOMESCO Finland
Subcutaneous
3.0
7.6
33
113
K21.0
ICD-10 Finland
Gastro-oesophageal reflux disease with oesophagitis
1.7
7.5
134
809
SHA03
NOMESCO Finland
Stomatognathic treatment, demanding
2.2
7.5
58
263
SPAT1260
SPAT
Consultation of another employee
1.5
7.5
222
1517
D01AE16
ATC
amorolfine; topical
1.7
7.5
147
911
J05AB01
ATC
aciclovir; systemic
1.4
7.5
319
2346
A07EA02
ATC
hydrocortisone; rectal
2.5
7.4
44
177
TNE11
NOMESCO Finland
Injection of diagnostic or therapeutic substance in sacroiliac joint
80.4
7.4
8
*
7209X
ICD-9 Finland
Ankylosing spondylitis and other inflammatory spondylopathies, Unspecified inflammatory spondylopathy
80.4
7.4
8
*
SPAT1250
SPAT
Comprehensive monitoring of chronic illness
1.5
7.4
284
2048
H10.3
ICD-10 Finland
Acute conjunctivitis, unspecified
1.8
7.3
107
610
WYA05
NOMESCO Finland
Emergency visit or other similar visit involving procedures
1.3
7.3
805
6860
U07
ICPC
Urine symptom/complaint other
2.0
7.3
82
430
R01AD58
ATC
fluticasone, combinations; nasal
1.4
7.2
443
3464
S18
ICPC
Laceration/cut
1.3
7.2
629
5189
NDL52
NOMESCO Finland
Tenosynovectomy of hand
4.5
7.2
17
38
M01AE01
ATC
ibuprofen; systemic, rectal
1.6
7.2
1631
15486
L01
ICPC
Neck symptom/complaint
1.5
7.2
231
1608
SPAT1153
SPAT
Removal of sutures
1.4
7.1
404
3119
SHA01
NOMESCO Finland
Stomatognathic treatment, simple
1.6
7.1
186
1237
L04AK01
ATC
leflunomide; oral
6.0
7.1
18
30
H20.8
ICD-10 Finland
Other iridocyclitis
6.0
7.1
18
30
R52.2
ICD-10 Finland
Other chronic pain
2.1
7.0
61
291
M47.9
ICD-10 Finland
Spondylosis, unspecified
2.5
6.9
42
171
QAA25
NOMESCO Finland
Destruction of lesion of head or neck
3.3
6.8
25
77
A01
ICPC
Pain general/multiple sites
1.7
6.8
122
738
K59.1
ICD-10 Finland
Functional diarrhoea
1.9
6.8
77
405
NA3BA
NOMESCO Finland
Lumbar spine extensive X-ray examination without contrast
9.3
6.8
13
14
Z01.6
ICD-10 Finland
Radiological examination, not elsewhere classified
1.6
6.8
149
951
K03.82
ICD-10 Finland
Split tooth for reasons other than trauma
1.4
6.8
377
2900
J01FA10
ATC
azithromycin; systemic
1.3
6.8
972
8553
WYA30
NOMESCO Finland
Treatment of a patient needing special arrangements
1.7
6.8
130
802
Z35.8
ICD-10 Finland
Supervision of other high-risk pregnancies
1.7
6.7
133
827
D94
ICPC
Chronic enteritis/ulcerative colitis
3.9
6.7
19
49
R4180
NOMESCO Finland
Podiatric therapy
3.4
6.7
23
68
N20.9
ICD-10 Finland
Urinary calculus, unspecified
2.4
6.7
45
193
R5599
NOMESCO Finland
Other rehabilitation service
2.4
6.6
43
181
CJE20
NOMESCO Finland
Phakoemulsification with implantation of artificial lens in posterior chamber
1.5
6.6
202
1389
R51.80
ICD-10 Finland
Headache
1.5
6.6
251
1803
J01FA06
ATC
roxithromycin; oral
1.3
6.6
598
4943
XCH00
NOMESCO Finland
Eye pressure measurement
2.2
6.6
55
258
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
1.5
6.6
184
1242
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
1.4
6.6
348
2653
K92.1
ICD-10 Finland
Melaena
2.1
6.6
57
272
A06AC51
ATC
ispaghula, combinations; oral
2.1
6.6
61
299
R35
ICD-10 Finland
Polyuria
1.9
6.6
85
468
RF310, ,
NOMESCO Finland
10.1
6.5
12
12
J20
ICD-10 Finland
Acute bronchitis
1.6
6.5
148
952
NA2AD
NOMESCO Finland
Thoracic spine CT examination
6.2
6.5
16
26
K03.64
ICD-10 Finland
Dental calculus supragingival
1.3
6.5
536
4375
ZYC01
NOMESCO Finland
Remote contact by phone
1.8
6.4
101
589
L13
ICPC
Hip symptom/complaint
1.5
6.4
200
1381
KMAK, ,
NOMESCO Finland
1.3
6.4
909
7962
RT350, ,
NOMESCO Finland
14.4
6.4
10
7
L85
ICPC
Acquired deformity of spine
14.4
6.4
10
7
-1, ,
NOMESCO Finland
1.3
6.3
547
4487
R20.2
ICD-10 Finland
Paraesthesia of skin
1.7
6.3
111
668
WZA00
NOMESCO Finland
Concise certificate
1.7
6.3
112
676
M47.2
ICD-10 Finland
Other spondylosis with radiculopathy
1.8
6.3
90
510
M16.6
ICD-10 Finland
Other secondary coxarthrosis, bilateral
8.2
6.3
13
16
SDA04
NOMESCO Finland
Demanding periodontal treatment
1.3
6.3
467
3750
M13.1
ICD-10 Finland
Monoarthritis, not elsewhere classified
3.4
6.3
22
66
L01CB
ATC
Podophyllotoxin derivatives
18.1
6.3
9
5
M06
ICD-10 Finland
Other rheumatoid arthritis
7.0
6.2
14
20
XX9AW
NOMESCO Finland
Production of copy from X-ray picture
2.1
6.2
59
292
SPAT1292
SPAT
Other function in accordance with SHToL (Finnish classification of nursing interventions)
1.8
6.1
94
545
K51.2
ICD-10 Finland
Ulcerative (chronic) proctitis
2.5
6.1
35
139
XG410
NOMESCO Finland
Flow-volume spirometry
2.1
6.1
53
253
NH1CG
NOMESCO Finland
Ankle and foot extensive MRI examination with high intensity magnet
2.9
6.1
28
99
L04AC07
ATC
tocilizumab; parenteral
8.6
6.1
12
14
NC1AA
NOMESCO Finland
Elbow X-ray examination without contrast
2.2
6.0
49
228
EG1AA
NOMESCO Finland
Mandibular joint X-ray examination
6.7
6.0
14
21
VALMI, ,
NOMESCO Finland
1.3
6.0
390
3066
ZXA10
NOMESCO Finland
Bilateral
1.5
6.0
204
1434
S01EE03
ATC
bimatoprost; ophthalmic
3.3
6.0
22
68
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
1464
6453
7.83
307.81
13.3
6.2
0.74
0.68
%
4.30
1434
6072
1649
8137
13.39
307.72
15.1
9.4
3.78
4.05
e9/l
8.19
1590
7144
1595
6742
13.10
307.65
12.7
6.5
—
—
—
0
0
1612
7139
13.16
307.65
12.7
6.1
0.04
0.04
e9/l
3.52
1553
6270
455
483
12.27
307.65
1.6
1.6
0.93
0.28
iu/ml
0.55
115
86
1612
7134
13.18
307.65
12.6
6.1
0.59
0.57
e9/l
5.19
1552
6270
1623
7377
13.33
307.65
12.8
6.1
2.14
1.97
e9/l
3.90
1580
6631
205
57
40.46
307.65
1.6
2.4
9.29
9.54
mg/l
0.12
161
49
1627
7401
13.60
307.65
13.0
6.4
0.18
0.19
e9/l
1.36
1577
6599
1489
6732
8.05
302.10
13.5
6.5
8.78
8.44
%
5.35
1457
6364
1483
6685
7.95
301.71
13.1
6.2
2.69
2.87
%
3.10
1454
6306
1491
6874
7.85
291.77
12.6
6.0
54.14
56.58
%
16.56
1460
6509
1495
6968
7.80
287.01
13.3
6.2
31.83
28.85
%
27.45
1466
6607
1713
10339
14.89
213.96
10.6
3.7
10.62
9.45
mm/h
4.10
1693
9711
1686
10565
10.57
185.80
12.0
7.3
72.14
75.14
u/l
3.41
1663
10051
432
1064
5.03
167.45
5.5
4.5
0.05
0.13
%
1.88
100
322
416
1027
4.97
160.31
4.7
4.2
0.30
0.64
%
3.31
103
323
163
153
11.62
152.73
1.3
1.4
23.00
30.00
iu/ml
—
5
7
1234
6763
3.63
143.01
6.3
4.2
0.00
0.00
estimate
0.50
297
1296
1237
6824
3.60
141.08
5.0
3.1
0.01
0.01
estimate
0.14
282
1217
1231
6780
3.59
140.55
4.9
3.1
0.00
0.00
estimate
1.08
304
1330
1179
6324
3.51
140.54
14.6
8.8
0.00
0.00
e9/l
0.94
1085
5215
186
284
7.19
118.19
3.6
3.7
3.78
4.04
e9/l
0.95
186
284
187
293
7.01
115.96
3.7
4.0
53.53
56.56
%
2.56
187
293
99
70
14.91
109.83
2.7
3.1
6.59
8.12
mg/l
0.96
82
60
94
63
15.69
107.33
2.5
2.4
98.41
98.14
au/ml
—
10
9
943
5409
2.56
82.59
2.6
2.3
74.10
73.54
nmol/l
0.28
901
5011
152
286
5.71
77.89
2.1
1.6
6818.49
11438.03
e6/l
1.02
117
215
157
321
5.26
73.34
1.7
1.4
—
—
—
0
0
1768
14920
12.09
64.52
22.1
11.5
14.59
21.82
mg/l
27.89
1625
11504
658
3537
2.36
61.94
6.2
3.4
0.00
0.01
estimate
1.28
291
1253
854
5378
2.12
51.97
5.5
3.1
—
—
—
0
0
1602
13130
3.02
49.34
22.2
13.9
14.69
14.67
%
0.02
1592
12903
412
1971
2.41
48.87
3.9
2.5
165.49
130.71
ug/g
1.09
355
1602
533
2912
2.18
45.68
6.0
3.2
1.02
1.02
kg/l
0.69
65
372
530
2927
2.15
43.91
2.6
2.1
2.93
2.81
mg/l
0.66
469
2536
469
2573
2.11
38.83
2.5
2.5
3.21
5.44
e6/l
5.29
433
2315
73
134
5.64
38.18
2.1
1.5
42.77
55.93
%
1.59
47
87
1776
16081
9.53
36.27
22.2
9.2
28.80
29.66
u/l
1.29
1765
15691
169
603
2.99
35.44
1.3
1.4
—
—
—
0
0
63
112
5.79
34.07
2.1
1.4
44.64
29.82
%
2.02
42
70
1630
14096
2.67
33.77
15.4
10.2
93.44
89.59
ml/min/173m2
14.23
1464
11649
562
3444
1.92
33.21
3.1
2.9
0.20
0.39
e6/l
3.22
452
2566
381
2080
2.06
31.14
2.4
2.5
0.72
0.91
e6/l
0.86
252
1136
595
3794
1.85
30.57
3.1
3.0
27.54
107.59
e6/l
1.35
482
2883
130
450
3.04
28.66
1.5
1.9
—
—
—
0
0
826
5946
1.72
27.13
5.2
7.0
1.22
1.21
mmol/l
1.58
710
5101
753
5312
1.72
26.41
5.1
6.4
1.22
1.21
mmol/l
1.85
712
4914
337
1897
1.96
24.72
2.2
2.5
13.28
14.44
umol/l
2.14
320
1777
229
1129
2.18
24.04
2.3
2.9
1.89
1.77
%
0.99
201
1022
739
5297
1.67
23.67
4.7
5.2
36.84
36.70
g/l
0.31
692
4994
229
1157
2.12
22.52
2.0
2.6
11.17
10.52
g/l
1.74
212
1062
192
906
2.25
22.39
1.5
1.9
1.20
1.30
g/l
0.59
184
849
35
53
6.72
22.16
1.7
1.4
5.36
5.73
%
0.03
11
11
65
178
3.75
20.77
2.5
3.2
1.16
1.21
%
0.06
56
166
837
6330
1.60
20.75
3.2
2.7
103.83
121.40
ug/l
2.22
804
5973
461
3029
1.70
19.82
1.4
1.5
2.87
2.35
g/l
5.06
308
2021
50
119
4.29
19.34
1.8
1.2
11016.37
44624.99
e6/l
0.72
38
87
1050
8479
1.57
18.92
4.3
3.6
380.36
883.83
e6/l
0.41
11
102
293
1759
1.80
17.08
2.2
2.5
2.38
2.38
g/l
0.04
276
1636
274
1621
1.81
16.75
2.3
2.6
22.99
24.66
%
1.10
245
1412
1787
17087
8.49
16.24
30.6
16.8
271.64
253.21
e9/l
26.52
1777
16748
1786
17073
7.91
16.16
30.5
16.9
40.96
41.39
%
2.88
1725
16264
1787
17106
8.30
15.80
30.6
16.7
4.55
4.64
e12/l
16.36
1775
16740
1787
17111
8.25
15.68
30.6
16.8
6.94
6.66
e9/l
5.52
1772
16736
292
1808
1.73
15.18
1.7
1.7
1093.47
1157.06
nmol/l
0.66
232
1420
861
6853
1.49
15.17
5.0
6.3
10.24
11.33
umol/l
1.60
815
6539
157
800
2.05
14.94
2.1
3.0
76.29
73.21
e9/l
0.44
115
597
128
618
2.15
14.03
1.2
1.2
2.07
1.34
u/ml
0.15
16
51
609
4605
1.49
13.36
1.9
1.8
92.87
97.02
pmol/l
1.68
375
2553
39
107
3.70
12.51
2.7
3.1
51.23
54.58
%
0.45
30
100
150
841
1.85
10.79
1.8
1.6
—
—
—
0
0
289
1954
1.57
10.38
2.7
2.7
2.38
2.12
e6/l
0.14
161
1019
1592
14828
1.64
10.12
13.6
12.5
139.54
139.67
mmol/l
1.65
1565
14487
350
2484
1.51
10.05
1.5
1.5
20.20
20.29
nmol/l
0.03
309
2193
674
5407
1.39
10.01
10.0
10.2
1.20
1.16
inr
0.57
223
1690
634
5054
1.39
9.70
3.3
3.4
33.52
35.66
u/l
0.25
608
4821
479
3638
1.43
9.67
2.3
2.4
3182.48
4534.48
umol/l
0.44
434
3304
1593
14888
1.61
9.40
13.7
12.6
3.92
3.96
mmol/l
5.28
1560
14517
92
460
2.05
9.26
1.3
2.0
1.51
1.50
g/l
0.01
70
399
47
177
2.70
9.00
1.2
1.3
—
—
—
0
0
41
149
2.79
8.41
1.5
1.5
—
—
—
0
0
333
2434
1.45
8.11
1.2
1.3
13.01
8.81
u/ml
0.43
146
1035
141
847
1.72
8.06
1.7
2.7
69.00
67.41
g/l
1.43
132
799
439
3422
1.37
7.32
1.3
1.3
1.11
1.64
u/ml
0.82
118
972
189
1267
1.55
6.98
3.2
4.6
216.90
238.93
u/l
1.93
177
1206
342
2585
1.40
6.82
1.2
1.3
23.27
26.18
iu/ml
0.25
104
815
470
3746
1.34
6.72
2.1
2.2
162.01
275.37
u/l
1.98
447
3559
104
605
1.76
6.69
1.3
1.3
165.38
223.22
miu/ml
0.87
37
287
430
3415
1.34
6.24
1.7
1.5
—
—
—
0
0
519
4252
1.31
6.02
2.6
2.6
60.20
58.28
u/l
0.17
488
3989
79
438
1.84
5.98
1.6
1.6
0.23
0.24
g/l
0.28
73
414
49
233
2.13
5.73
1.8
1.6
—
—
—
0
0
34
138
2.49
5.71
1.2
1.2
566.00
200.00
titre
—
5
25
21
66
3.21
5.60
2.5
2.2
—
—
—
0
0
80
457
1.79
5.52
1.6
1.6
1.22
1.19
g/l
0.52
74
432
103
632
1.67
5.51
2.1
2.7
0.29
0.16
e6/l
0.88
96
609
157
1066
1.52
5.49
2.3
2.3
21.12
23.15
au/ml
0.14
14
101
36
154
2.36
5.42
1.0
1.1
—
—
—
0
0
56
287
1.98
5.39
1.5
2.5
0.00
0.02
g/l
0.50
50
276
57
295
1.96
5.34
1.6
1.4
—
—
—
0
0
487
4011
1.29
5.33
2.5
3.3
2.34
2.35
mmol/l
1.91
446
3664
29
113
2.59
5.31
1.0
1.0
—
—
—
0
0
870
7695
1.25
5.24
4.6
4.9
6.40
6.59
mmol/l
2.21
818
7200
30
123
2.46
4.97
1.1
1.2
49.03
56.31
u/l
0.68
30
114
20
66
3.05
4.95
2.6
2.2
—
—
—
0
0
30
124
2.44
4.89
2.1
2.5
33.13
32.74
pg
0.18
30
124
10
13
7.73
4.85
1.6
1.5
3.67
3.81
mg/l
—
10
13
1415
13305
1.30
4.82
3.9
4.3
1.71
1.98
mu/l
1.50
1331
12495
242
1831
1.37
4.73
1.9
1.8
—
—
—
0
0
550
4665
1.26
4.64
3.7
3.0
25.16
40.39
ng/l
2.14
328
2736
399
3256
1.29
4.61
1.8
1.8
1.01
0.93
mg/l
0.20
296
2383
186
1352
1.42
4.61
2.0
2.1
337.47
366.28
nmol/l
1.37
171
1265
73
432
1.72
4.52
1.3
1.1
—
—
—
0
0
73
432
1.72
4.52
1.3
1.1
—
—
—
0
0
63
358
1.79
4.48
2.5
3.1
—
—
—
0
0
310
2455
1.32
4.47
1.7
1.6
65201860.66
31963043.72
pmol/l
0.30
273
2140
58
322
1.83
4.45
1.5
2.6
0.10
0.88
g/l
3.64
51
298
86
534
1.64
4.45
1.8
1.9
—
—
—
0
0
344
2767
1.30
4.43
2.8
3.0
553.99
949.60
ng/l
2.27
275
2271
22
82
2.70
4.42
2.0
2.3
0.67
2.40
u/field
1.58
12
47
25
100
2.52
4.38
1.1
1.2
—
43.20
—
0
5
315
2520
1.30
4.21
1.9
2.0
—
—
—
0
0
24
97
2.49
4.13
1.1
1.2
—
5.17
—
0
6
1191
11057
1.23
4.06
3.4
3.7
14.76
14.52
pmol/l
2.84
1106
10319
8
10
8.03
4.06
1.9
2.0
—
—
—
0
0
64
377
1.72
4.06
1.5
2.3
—
—
—
0
0
251
1968
1.32
3.88
2.5
2.9
2.43
2.43
mmol/l
0.15
221
1749
283
2262
1.30
3.80
1.9
2.0
—
—
—
0
0
48
265
1.83
3.80
1.6
2.6
0.00
0.00
g/l
-0.00
42
254
17
60
2.85
3.79
1.1
1.1
12.41
13.33
u/l
0.11
17
52
209
1601
1.35
3.79
3.0
2.9
10.17
7.70
umol/l
0.41
185
1395
14
44
3.20
3.78
1.6
2.0
—
—
—
0
0
33
160
2.08
3.77
1.8
1.5
—
—
—
0
0
33
160
2.08
3.77
1.8
1.5
—
—
—
0
0
33
161
2.07
3.72
1.8
1.5
—
—
—
0
0
63
380
1.68
3.69
1.9
1.7
—
—
—
0
0
15
50
3.02
3.69
3.1
2.5
—
—
—
0
0
17
62
2.76
3.59
1.1
1.1
81.65
87.48
u/l
0.13
17
54
33
165
2.02
3.50
1.8
1.5
—
—
—
0
0
19
75
2.55
3.46
1.0
1.1
1702.32
1566.15
miu/ml
0.22
19
75
42
230
1.85
3.43
1.3
1.6
—
—
—
0
0
130
938
1.42
3.41
3.2
3.9
1.22
1.23
mmol/l
0.69
121
810
159
1189
1.37
3.38
2.5
2.3
0.23
0.23
g/l
0.45
149
1122
74
477
1.58
3.36
2.6
1.9
—
—
—
0
0
1241
11666
1.21
3.31
3.4
3.3
—
—
—
0
0
32
162
1.99
3.30
1.8
1.5
—
—
—
0
0
50
297
1.70
3.14
1.3
1.7
—
—
—
0
0
14
50
2.81
3.09
3.3
2.5
—
—
—
0
0
14
50
2.81
3.09
3.3
2.5
—
—
—
0
0
43
246
1.77
3.08
1.0
1.1
—
—
—
0
0
705
6333
1.19
3.08
2.5
2.4
—
—
—
0
0
22
99
2.24
3.06
1.5
2.0
—
—
—
0
0
13
41
3.19
3.05
3.5
4.3
—
—
—
0
0
43
247
1.76
3.05
1.2
1.2
—
36.67
—
0
6
(40770918) von Willebrand factor (vWf).activity actual/normal in Platelet poor plasma by Immunoassay
0
77
0.00
2.96
0.0
1.7
—
130.03
—
0
72
48
288
1.68
2.93
1.2
1.2
—
—
—
0
0
369
3134
1.22
2.93
2.4
2.2
—
—
—
0
0
199
1578
1.29
2.86
4.2
6.9
1.03
1.03
mmol/l
0.08
185
1497
30
157
1.93
2.85
1.4
1.3
—
—
—
0
0
23
109
2.12
2.85
1.3
1.1
—
—
—
0
0
23
109
2.12
2.85
1.3
1.1
—
—
—
0
0
31
165
1.89
2.81
1.8
1.5
—
—
—
0
0
59
378
1.58
2.80
1.2
1.2
4.13
10.22
u/ml
—
7
63
142
1078
1.34
2.78
2.6
2.3
74.70
75.24
ml/min/173m2
0.05
46
399
24
117
2.07
2.77
2.3
1.8
—
—
—
0
0
24
117
2.07
2.77
2.3
1.8
—
—
—
0
0
24
117
2.07
2.77
2.3
1.8
—
—
—
0
0
95
675
1.43
2.76
1.9
2.1
38.41
40.00
u/l
0.46
90
622
58
372
1.58
2.75
1.2
1.2
1.78
2.48
u/ml
—
5
38
23
111
2.09
2.73
1.3
1.1
—
—
—
0
0
23
111
2.09
2.73
1.3
1.1
—
—
—
0
0
23
111
2.09
2.73
1.3
1.1
—
—
—
0
0
65
434
1.52
2.59
2.2
1.8
—
—
—
0
0
105
776
1.37
2.46
2.3
2.7
98.93
142.49
ng/l
1.24
94
683
157
1236
1.30
2.41
1.5
1.8
—
—
—
0
0
167
2072
0.79
2.31
1.7
1.7
—
—
—
0
0
159
1262
1.29
2.30
1.5
1.8
—
—
—
0
0
83
600
1.40
2.24
1.6
1.6
—
—
—
0
0
5
9
5.57
2.21
1.0
6.4
—
—
—
0
0
395
3470
1.18
2.15
4.2
4.0
94.37
94.05
%
0.10
384
3386
17
81
2.11
2.13
1.5
1.4
3.25
7.30
u/l
1.13
12
68
21
110
1.92
2.06
1.1
1.1
—
—
—
0
0
110
845
1.32
2.05
1.1
1.1
—
—
—
0
0
22
392
0.56
2.05
1.4
1.9
7.50
4.76
iu/l
—
5
153
47
312
1.52
1.99
1.2
1.2
—
—
—
0
0
32
196
1.64
1.90
1.2
1.3
—
—
—
0
0
0
52
0.00
1.88
0.0
1.4
—
94.48
—
0
29
0
54
0.00
1.85
0.0
1.1
—
93.39
—
0
31
12
53
2.27
1.80
2.4
3.5
—
—
—
0
0
7
23
3.05
1.80
1.0
1.1
—
—
—
0
0
7
24
2.92
1.72
1.1
1.2
—
—
—
0
0
7
24
2.92
1.72
1.0
1.2
—
—
—
0
0
11
48
2.30
1.70
1.2
1.6
111.03
95.15
nmol/24h
0.26
11
48
108
855
1.28
1.66
1.3
1.4
—
—
—
0
0
19
105
1.82
1.63
1.1
2.0
—
—
—
0
0
220
1891
1.19
1.57
1.8
2.3
30.21
29.69
s
0.59
213
1841
91
712
1.29
1.55
2.7
3.1
1.94
1.51
mmol/l
0.57
66
529
57
420
1.37
1.47
1.9
2.3
9.18
10.35
mg/l
0.51
51
394
131
1080
1.23
1.45
7.6
8.3
1.32
1.36
mmol/l
0.17
125
1053
261
2292
1.16
1.44
1.5
1.5
—
—
—
0
0
11
52
2.12
1.44
1.7
1.6
—
—
—
0
0
263
2315
1.16
1.41
4.0
3.3
652.04
570.84
ng/l
0.07
170
1549
90
715
1.27
1.39
1.5
1.5
—
—
—
0
0
173
1474
1.19
1.38
6.0
5.7
—
—
—
0
0
102
824
1.25
1.37
2.9
4.2
69.15
82.39
ng/l
0.90
96
742
19
112
1.70
1.35
1.0
1.1
1.70
1.06
u/l
—
6
58
8
34
2.36
1.29
1.9
1.1
91.63
97.91
%
—
8
34
36
251
1.44
1.29
1.1
1.1
—
—
—
0
0
57
745
0.76
1.27
2.3
1.8
6.89
3.92
mg/l
0.51
47
534
92
744
1.25
1.25
2.9
3.1
5.13
5.17
kpa
0.16
87
713
1440
14047
1.13
1.24
3.8
3.8
5.72
5.85
mmol/l
4.79
1364
13152
137
1161
1.19
1.19
8.5
10.3
95.96
96.21
%
0.15
132
1120
6
127
0.47
1.16
1.8
1.6
8.02
7.81
mmol/l
—
6
121
10
50
2.01
1.16
1.1
2.3
—
55782.88
—
0
8
171
1481
1.17
1.16
3.5
3.9
30.91
30.31
%
0.37
140
1109
0
33
0.00
1.16
0.0
1.4
—
—
—
0
0
36
257
1.41
1.16
1.1
1.1
—
—
—
0
0
153
1314
1.18
1.15
3.2
2.6
37.46
74.44
u/l
0.53
133
1157
5
20
2.50
1.15
1.0
1.9
—
—
—
0
0
5
20
2.50
1.15
1.6
1.8
—
—
—
0
0
20
127
1.58
1.11
2.4
2.0
34.50
22.73
mg/l
—
6
40
26
176
1.48
1.10
1.3
1.8
—
—
—
0
0
45
338
1.34
1.08
1.6
1.5
12946.67
1894.77
e6/l
0.41
40
274
45
338
1.34
1.08
1.5
1.4
31.63
13.53
e6/l
0.37
38
265
11
188
0.58
0.99
1.5
1.1
—
—
—
0
0
5
23
2.18
0.98
1.0
1.0
—
—
—
0
0
10
54
1.86
0.96
1.0
1.0
—
—
—
0
0
1363
13313
1.10
0.96
4.6
4.8
37.17
38.86
mmol/mol
11.57
1306
12621
39
294
1.33
0.94
2.1
3.9
37.71
66.31
mg/l
0.68
29
229
39
294
1.33
0.94
2.1
3.9
29.13
32.82
mg/l
0.34
29
228
31
225
1.38
0.94
2.1
1.9
—
—
—
0
0
31
225
1.38
0.94
2.1
1.9
—
—
—
0
0
41
312
1.32
0.93
2.0
1.8
—
—
—
0
0
110
939
1.18
0.93
3.2
2.2
7.34
8.00
ug/l
0.11
98
852
29
209
1.39
0.92
3.3
4.3
788.60
231.87
u/ml
0.38
23
199
149
1306
1.15
0.91
8.1
9.6
5.20
5.12
kpa
0.32
140
1255
149
1306
1.15
0.91
8.1
9.5
13.14
12.78
kpa
0.36
140
1257
119
1027
1.17
0.89
3.1
4.6
216.43
19.95
ug/l
0.71
90
819
148
1299
1.15
0.89
8.2
9.6
1.14
0.95
mmol/l
0.27
118
1038
73
603
1.22
0.88
10.5
12.4
24.91
24.30
mmol/l
0.88
68
593
492
4623
1.09
0.87
3.8
3.7
1.91
1.83
ug/l
0.17
445
4253
143
1255
1.15
0.86
3.2
3.0
—
—
—
0
0
27
195
1.39
0.86
1.3
1.5
—
—
—
0
0
59
478
1.24
0.85
1.4
1.3
—
—
—
0
0
30
222
1.36
0.84
2.3
2.0
—
—
—
0
0
10
57
1.76
0.83
1.2
1.4
—
—
—
0
0
51
410
1.25
0.80
4.2
3.9
13117.29
3379.24
u/ml
0.45
44
352
55
449
1.23
0.76
1.2
1.1
—
—
—
0
0
18
124
1.46
0.75
1.3
1.4
73.39
76.18
umol/l
0.33
18
124
9
54
1.67
0.74
1.7
1.2
—
64.44
—
0
9
32
245
1.31
0.74
1.9
2.2
138.17
135.72
g/l
0.21
23
176
69
817
0.84
0.73
1.6
1.5
—
—
—
0
0
21
288
0.73
0.72
1.5
1.5
0.19
0.32
nmol/l
2.26
14
231
9
56
1.61
0.72
1.2
1.9
—
—
—
0
0
9
56
1.61
0.72
1.2
1.9
—
—
—
0
0
9
57
1.58
0.71
1.2
1.4
—
—
—
0
0
39
488
0.79
0.71
1.6
1.5
—
—
—
0
0
23
169
1.37
0.69
1.0
1.2
—
—
—
0
0
30
232
1.30
0.66
1.8
1.7
—
—
—
0
0
5
28
1.79
0.66
1.0
1.4
—
—
—
0
0
226
2080
1.10
0.65
3.2
3.9
0.81
0.82
mmol/l
0.84
210
1986
7
44
1.59
0.65
1.1
1.4
—
—
—
0
0
8
129
0.62
0.64
1.6
1.4
2.90
1.90
mmol/l
—
8
121
6
101
0.59
0.62
2.5
1.7
—
—
—
0
0
80
695
1.16
0.60
1.7
2.3
2510.37
4624.76
u/l
0.61
29
264
8
51
1.57
0.60
1.3
1.4
—
—
—
0
0
8
51
1.57
0.60
1.3
1.4
—
—
—
0
0
0
21
0.00
0.60
0.0
1.0
—
—
—
0
0
0
21
0.00
0.60
0.0
1.0
—
0.03
—
0
12
45
372
1.22
0.59
1.4
1.4
279.72
307.02
ug/g
0.31
25
205
0
22
0.00
0.59
0.0
3.0
—
—
—
0
0
0
22
0.00
0.59
0.0
1.3
—
—
—
0
0
0
22
0.00
0.59
0.0
1.0
—
0.00
—
0
14
0
22
0.00
0.59
0.0
1.2
—
—
—
0
0
11
72
1.53
0.59
1.6
1.2
264.36
517.03
u/l
0.64
11
63
37
453
0.81
0.58
1.5
1.4
—
—
—
0
0
0
23
0.00
0.58
0.0
1.2
—
—
—
0
0
0
23
0.00
0.58
0.0
1.1
—
—
—
0
0
0
23
0.00
0.58
0.0
2.2
—
0.48
—
0
17
37
452
0.81
0.57
1.5
1.4
—
—
—
0
0
29
229
1.27
0.57
1.3
1.7
—
—
—
0
0
6
36
1.67
0.56
1.0
1.2
—
—
—
0
0
37
451
0.82
0.56
1.5
1.4
—
—
—
0
0
37
450
0.82
0.55
1.5
1.4
—
—
—
0
0
11
160
0.69
0.55
1.3
1.7
—
—
—
0
0
11
160
0.69
0.55
1.3
1.7
—
—
—
0
0
6
37
1.62
0.55
1.0
1.1
—
—
—
0
0
111
996
1.12
0.54
2.0
1.9
—
—
—
0
0
11
74
1.49
0.53
1.1
1.3
170.82
174.28
mmol/24h
0.04
11
74
24
305
0.78
0.53
2.8
3.4
38.20
37.24
umol/l
0.08
24
283
37
305
1.22
0.52
2.2
1.9
—
—
—
0
0
32
391
0.82
0.51
1.3
1.5
—
—
—
0
0
13
92
1.42
0.50
2.1
1.6
—
1206516.67
—
0
9
392
3734
1.06
0.50
1.6
1.6
1.40
1.49
mmol/l
1.11
342
3229
10
67
1.50
0.49
1.5
1.8
—
—
—
0
0
10
67
1.50
0.49
1.5
1.8
—
—
—
0
0
22
172
1.28
0.48
1.3
1.6
—
—
—
0
0
16
119
1.35
0.48
1.9
1.7
—
—
—
0
0
25
199
1.26
0.48
2.0
2.3
6.29
6.09
umol/l
0.04
15
143
7
48
1.46
0.46
1.0
2.0
—
—
—
0
0
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
40
337
1.19
0.46
3.5
3.2
0.34
0.34
u/ml
0.03
24
175
10
142
0.70
0.46
1.1
1.5
0.84
1.01
g/l
—
10
142
7
49
1.43
0.46
1.3
2.0
—
—
—
0
0
17
129
1.32
0.45
1.2
1.2
0.19
0.56
u/ml
—
8
70
59
515
1.15
0.45
1.5
1.5
—
—
—
0
0
1102
11222
0.95
0.44
3.2
3.1
49.57
46.90
u/l
0.47
1051
10721
9
127
0.71
0.43
1.0
1.2
—
—
—
0
0
18
140
1.29
0.42
1.0
1.1
—
—
—
0
0
0
15
0.00
0.41
0.0
1.2
—
—
—
0
0
8
59
1.36
0.41
1.0
1.1
—
—
—
0
0
8
60
1.33
0.40
1.9
1.4
9.01
8.39
ug/l
—
8
60
246
2597
0.94
0.40
1.9
1.9
1.51
1.44
%
0.85
224
2355
12
88
1.37
0.40
1.3
1.2
—
—
—
0
0
0
18
0.00
0.40
0.0
1.3
—
—
—
0
0
41
475
0.86
0.40
1.6
1.6
—
—
—
0
0
7
105
0.67
0.39
1.3
1.5
—
—
—
0
0
0
19
0.00
0.39
0.0
1.0
—
1.78
—
0
11
19
151
1.26
0.38
3.0
1.9
—
—
—
0
0
137
1273
1.08
0.37
2.1
2.0
—
—
—
0
0
117
1080
1.09
0.37
1.1
1.2
74.56
140.88
iu/ml
1.32
41
429
175
1645
1.07
0.36
2.2
2.3
14.13
13.85
nmol/l
0.22
159
1527
119
1102
1.09
0.36
5.0
9.2
8.09
8.38
mmol/l
0.23
112
1058
286
2733
1.06
0.35
2.6
2.5
0.70
0.67
ug/l
0.29
184
1501
42
367
1.15
0.34
1.3
1.5
—
17.12
—
0
7
16
197
0.81
0.31
1.2
1.1
—
—
—
0
0
77
707
1.09
0.29
7.4
9.0
25.20
24.52
mmol/l
1.37
71
672
23
270
0.85
0.28
1.0
1.0
0.01
0.40
u/ml
—
8
76
32
279
1.15
0.28
1.1
1.0
2.90
2.45
u/ml
—
6
145
15
121
1.24
0.28
1.7
1.3
—
—
—
0
0
10
76
1.32
0.28
1.5
1.7
—
—
—
0
0
15
122
1.23
0.27
1.7
1.3
—
—
—
0
0
32
281
1.14
0.26
1.4
1.2
3.92
5.33
u/ml
0.19
13
89
25
288
0.87
0.25
1.0
1.1
4.64
5.01
u/ml
0.05
13
114
38
339
1.12
0.25
1.3
1.6
92.27
116.12
u/ml
0.81
11
63
27
309
0.87
0.25
1.0
1.0
2.29
3.18
u/ml
0.39
15
143
19
224
0.85
0.25
2.5
2.7
1.34
1.55
mmol/l
0.71
19
218
411
4000
1.04
0.24
3.1
3.4
8.44
8.48
mmol/l
0.06
369
3488
84
785
1.07
0.23
1.6
1.9
34.33
36.65
nmol/l
0.65
84
767
11
136
0.81
0.23
1.8
1.7
—
—
—
0
0
7
92
0.76
0.22
1.0
1.0
—
—
—
0
0
10
79
1.27
0.22
1.0
1.1
100.06
218.84
iu/ml
—
10
79
1527
15182
1.04
0.22
4.2
4.2
2.86
2.91
mmol/l
1.66
1462
14388
10
124
0.81
0.21
1.1
1.4
1.52
1.53
g/l
—
10
124
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
0
11
0.00
0.21
0.0
1.0
—
21.03
—
0
6
0
11
0.00
0.21
0.0
1.1
—
—
—
0
0
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
0
10
0.00
0.21
0.0
2.7
—
—
—
0
0
16
135
1.19
0.21
3.4
2.0
—
—
—
0
0
8
105
0.76
0.21
1.1
1.3
—
—
—
0
0
5
43
1.16
0.21
1.0
2.2
54.34
47.87
ug/l
—
5
43
0
13
0.00
0.21
0.0
1.1
—
—
—
0
0
0
13
0.00
0.21
0.0
5.9
—
494.69
—
0
13
0
14
0.00
0.20
0.0
1.0
—
—
—
0
0
79
742
1.07
0.20
1.5
1.8
—
—
—
0
0
1437
14460
0.97
0.20
3.6
3.6
1.32
1.36
mmol/l
1.47
1370
13675
1512
15036
1.04
0.20
4.0
3.9
4.73
4.78
mmol/l
1.38
1454
14330
9
113
0.80
0.20
1.6
2.2
—
—
—
0
0
9
115
0.78
0.20
2.8
4.1
—
—
—
0
0
50
541
0.92
0.19
1.4
1.4
—
—
—
0
0
80
754
1.06
0.19
1.5
1.6
254.23
279.45
mu/l
0.22
71
695
6
53
1.13
0.18
1.0
1.0
—
—
—
0
0
32
290
1.11
0.18
1.2
1.1
—
—
—
0
0
26
233
1.12
0.17
1.9
2.3
18.04
17.17
%
0.36
14
119
1505
14977
1.03
0.17
3.9
3.9
1.43
1.41
mmol/l
1.62
1441
14221
20
177
1.13
0.16
1.0
1.1
—
—
—
0
0
11
92
1.20
0.16
1.5
1.7
—
—
—
0
0
55
586
0.94
0.16
4.4
3.9
24.25
24.31
mmol/l
0.07
55
575
24
216
1.11
0.15
1.1
1.4
183.76
216.03
pmol/l
0.32
24
216
9
78
1.15
0.15
5.2
2.5
26.16
432.59
ug/l
—
9
68
28
307
0.91
0.15
2.0
2.2
73.75
140.41
ug/min
1.17
17
188
9
82
1.10
0.15
3.8
3.4
894.00
813.15
u/ml
—
9
82
12
139
0.86
0.14
1.1
1.4
1.53
1.40
nmol/l
0.19
12
129
42
392
1.07
0.14
1.2
1.2
—
—
—
0
0
8
99
0.81
0.13
2.3
1.7
—
—
—
0
0
24
218
1.10
0.13
3.1
3.4
3.60
111.92
u/ml
0.81
24
213
(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
11
94
1.17
0.13
1.0
1.1
—
—
—
0
0
45
423
1.07
0.12
1.6
2.3
255.39
285.19
ug/l
0.07
37
398
26
283
0.92
0.12
1.5
1.5
—
—
—
0
0
16
142
1.13
0.12
1.3
2.0
—
—
—
0
0
96
925
1.04
0.12
2.2
3.4
4.68
4.61
pmol/l
0.11
87
835
33
352
0.94
0.10
1.0
1.1
0.36
2.03
u/ml
3.50
19
166
13
115
1.13
0.10
3.4
2.5
—
—
—
0
0
100
968
1.04
0.10
1.4
1.4
23.33
25.49
iu/l
0.29
88
825
353
3482
1.02
0.09
3.0
3.4
607.20
402.10
mg/l
0.27
225
2329
104
1069
0.97
0.08
3.7
3.8
1.86
2.02
mmol/l
0.23
91
887
5
64
0.78
0.08
1.0
1.1
—
—
—
0
0
38
399
0.95
0.08
1.0
1.1
2.64
2.27
u/ml
0.06
18
198
7
68
1.03
0.07
1.1
1.2
—
—
—
0
0
20
215
0.93
0.07
1.3
1.6
—
—
—
0
0
8
74
1.08
0.07
1.0
1.1
—
—
—
0
0
15
137
1.10
0.07
1.1
1.1
—
—
—
0
0
7
81
0.86
0.07
1.0
1.1
—
—
—
0
0
11
122
0.90
0.07
1.8
2.3
4.15
4.01
mmol/l
0.53
11
122
11
122
0.90
0.07
1.8
2.3
106.00
105.70
mmol/l
0.08
11
122
17
183
0.93
0.06
1.3
1.8
—
—
—
0
0
36
376
0.96
0.06
1.2
1.2
330.41
262.36
u/ml
0.55
22
235
25
237
1.06
0.05
1.5
1.3
—
—
—
0
0
25
237
1.06
0.05
1.5
1.3
—
—
—
0
0
20
188
1.06
0.05
2.2
2.3
—
—
—
0
0
54
525
1.03
0.05
1.4
1.5
—
—
—
0
0
36
350
1.03
0.03
1.6
1.7
—
—
—
0
0
13
122
1.07
0.02
1.1
1.2
—
—
—
0
0
12
114
1.05
0.00
1.2
3.9
—
—
—
0
0
13
124
1.05
0.00
2.7
2.6
—
—
—
0
0
368
3673
1.00
0.00
3.4
3.3
21.59
20.94
%
0.36
165
1369
14
135
1.04
0.00
2.1
1.9
—
—
—
0
0
27
275
0.98
0.00
3.0
3.1
18.03
24.32
mg/l
0.49
19
168
19
191
0.99
0.00
1.0
1.1
—
—
—
0
0
20
199
1.01
0.00
1.0
1.1
—
—
—
0
0
21
209
1.00
0.00
1.1
1.1
104.71
97.27
%
0.60
21
199
28
281
1.00
0.00
1.3
1.2
5.20
4.45
u/ml
—
10
118
35
351
1.00
0.00
1.0
1.1
0.47
1.36
u/ml
1.12
13
139
63
631
1.00
0.00
1.3
1.4
7.75
8.20
u/l
0.12
56
522
16
156
1.03
0.00
1.8
1.8
20.00
19.72
nmol/l
0.05
16
147
364
3644
1.00
0.00
3.6
3.9
6.45
9.95
mg/mmol
1.71
238
2404
37
368
1.01
0.00
1.0
1.1
2.16
5.87
u/ml
2.43
19
188
11
107
1.03
0.00
1.9
1.2
—
—
—
0
0
43
427
1.01
0.00
2.8
3.1
1.27
1.37
mg/l
0.64
43
401
0
9
0.00
-0.00
0.0
1.8
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.7
—
2.13
—
0
6
0
5
0.00
-0.00
0.0
3.8
—
7.62
—
0
5
0
6
0.00
-0.00
0.0
11.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
6
61
0.98
-0.00
5.7
3.4
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
5
59
0.85
-0.00
1.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
8.17
—
0
6
7
69
1.01
-0.00
2.4
2.1
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
4.3
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint M13_ANKYLOSPON_STRICT and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| M13_ANKYLOSPON_STRICT | 0.709 [0.53, 0.95] | 0.019 |
| Birth year | 0.993 [0.98, 1.0] | 0.138 |
During the follow-up period (1.1.1998 — 31.12.2019), 51 out of 2980 females with M13_ANKYLOSPON_STRICT died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| M13_ANKYLOSPON_STRICT | 0.829 [0.71, 0.96] | 0.015 |
| Birth year | 0.988 [0.98, 1.0] | 0.014 |
During the follow-up period (1.1.1998 — 31.12.2019), 218 out of 4769 males with M13_ANKYLOSPON_STRICT died.
Mortality risk
Mortality risk for people of age
years, who have M13_ANKYLOSPON_STRICT.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.071% | 0.139% |
| 5 | 0.43% | 1.001% |
| 10 | 1.008% | 2.594% |
| 15 | 1.862% | 4.725% |
| 20 | 3.295% | 8.268% |
Relationships between endpoints
↥Index endpoint: M13_ANKYLOSPON_STRICT – Ankylosing spondylitis, strict definition
GWS hits: 13
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
Loading data