Maternal care for known or suspected disproportion

O15_MATERN_CARE_DISPROP

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

519972

1. Apply sex-specific rule

only females

293218

2. Check conditions

None

293218

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 O33
  • Cause of death: ICD-10 O33

2 out of 7 registries used, show all original rules.

1823

4. Check minimum number of events

None

1823

5. Include endpoints

None

1823

6. Filter based on genotype QC (FinnGen only)

1741

Control definitions (FinnGen only)

Control exclude
O15_MATERN_CARE

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF3
Parent code in ICD-10
O30-O48
Name in latin
Cura matris propter disproportionem fetopelvinam notam sive suspectam

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 13757 13757 -
Only index persons 13623 13623 -
Unadjusted period prevalence (%)
Whole population 0.39 0.39 -
Only index persons 0.50 0.50 -
Median age at first event (years)
Whole population - 30.64 -
Only index persons - 30.64 -

-FinnGen-

Key figures

All Female Male
Number of individuals 1741 1741 -
Unadjusted period prevalence (%) 0.62 0.62 -
Median age at first event (years) 30.87 30.87 -

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
1823
Matched controls
18230
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
O33.5
ICD-10 Finland
Maternal care for disproportion due to unusually large fetus
+∞
307.7
407
*
O82.10
ICD-10 Finland
Delivery by emergency caesarean section
17.8
307.7
540
421
O82.0
ICD-10 Finland
Delivery by elective caesarean section
108.1
307.7
900
163
O33.3
ICD-10 Finland
Maternal care for disproportion due to outlet contraction of pelvis
+∞
307.7
341
*
O47.0
ICD-10 Finland
False labour before 37 completed weeks of gestation
16.5
307.7
298
213
MCA10
NOMESCO Finland
Lower uterine segment caesarean section
80.7
307.7
1410
740
O33.9
ICD-10 Finland
Maternal care for disproportion, unspecified
+∞
307.7
436
*
O34.2
ICD-10 Finland
Maternal care due to uterine scar from previous surgery
16384.0
307.7
954
*
O36.6
ICD-10 Finland
Maternal care for excessive fetal growth
1712.2
303.8
287
*
O33.1
ICD-10 Finland
Maternal care for disproportion due to generally contracted pelvis
+∞
288.4
269
*
O32.1
ICD-10 Finland
Maternal care for breech presentation
412.5
223.5
220
6
O33.4
ICD-10 Finland
Maternal care for disproportion of mixed maternal and fetal origin
+∞
220.4
207
*
O33.2
ICD-10 Finland
Maternal care for disproportion due to inlet contraction of pelvis
+∞
184.6
174
*
Z36.3
ICD-10 Finland
Antenatal screening for malformations using ultrasound and other physical methods
3.9
181.7
1003
4327
O63.0
ICD-10 Finland
Prolonged first stage (of labour)
13.7
173.0
166
132
O65.4
ICD-10 Finland
Obstructed labour due to fetopelvic disproportion, unspecified
36.0
162.0
102
30
O24.4
ICD-10 Finland
Diabetes mellitus arising in pregnancy
4.7
149.0
411
1061
Z35.8
ICD-10 Finland
Supervision of other high-risk pregnancies
4.5
131.7
378
1000
MA2AE
NOMESCO Finland
Ultrasound examination of pregnancy (at 12. week of gestaion or later) including basic examination of fetus
3.7
130.2
537
1840
MA2DE
NOMESCO Finland
Detailed ultrasound examination of fetus including color doppler method
5.0
130.0
316
731
8811
FHL
Cesarean section
5.1
122.6
288
646
O47.1
ICD-10 Finland
False labour at or after 37 completed weeks of gestation
634.0
121.7
119
*
O65.1
ICD-10 Finland
Obstructed labour due to generally contracted pelvis
44.1
114.0
68
16
O48
ICD-10 Finland
Prolonged pregnancy
+∞
111.6
106
*
MA2HE
NOMESCO Finland
Detailed morfological ultrasound examination of fetus
3.2
108.8
599
2423
O33.0
ICD-10 Finland
Maternal care for disproportion due to deformity of maternal pelvic bones
+∞
96.7
92
*
ZXD05
NOMESCO Finland
Urgent procedure
2.8
95.4
721
3430
LGA10
NOMESCO Finland
Sterilisation by destruction or division of Fallopian tubes
13.0
88.5
86
69
O24.9
ICD-10 Finland
Diabetes mellitus in pregnancy, unspecified
7.7
86.8
125
172
Z34.8
ICD-10 Finland
Supervision of other normal pregnancy
2.8
81.7
544
2391
MAA00
NOMESCO Finland
Amniocentesis
8.8
80.4
103
123
LGA20
NOMESCO Finland
Sterilisation by constriction of Fallopian tubes
12.1
79.5
81
70
Z35.9
ICD-10 Finland
Supervision of high-risk pregnancy, unspecified
5.4
75.4
158
317
Z35.2
ICD-10 Finland
Supervision of pregnancy with other poor reproductive or obstetric history
9.1
74.7
93
107
6533B
ICD-9 Finland
Disproportion, Outlet contraction of pelvis[PELVIS ANGUSTA, ANOM APERT INFER,SYNNYTYKSEN AIKANA]
17.0
73.1
61
37
O40
ICD-10 Finland
Polyhydramnios
+∞
70.3
67
*
O35.1
ICD-10 Finland
Maternal care for (suspected) chromosomal abnormality in fetus
+∞
67.1
64
*
O42.9
ICD-10 Finland
Premature rupture of membranes, unspecified
+∞
63.9
61
*
O99.80
ICD-10 Finland
The fear of childbirth
4.0
59.4
178
475
O24.0
ICD-10 Finland
Diabetes mellitus in pregnancy: Pre-existing diabetes mellitus, insulin-dependent
6.8
59.1
95
147
XMA22
NOMESCO Finland
General examination of pregnant woman
3.3
59.1
249
834
O30.0
ICD-10 Finland
Twin pregnancy
+∞
58.7
56
*
O41.0
ICD-10 Finland
Oligohydramnios
+∞
58.7
56
*
Z36.8
ICD-10 Finland
Other antenatal screening
5.5
58.3
117
225
6531B
ICD-9 Finland
Disproportion, Generally contracted pelvis[PELVIS ANGUSTA,SYNNYTYKSEN AIKANA]
15.1
56.4
50
34
O64.0
ICD-10 Finland
Obstructed labour due to incomplete rotation of fetal head
5.9
55.8
103
183
O65.3
ICD-10 Finland
Obstructed labour due to pelvic outlet and mid-cavity contraction
72.3
55.5
63
9
WX306
NOMESCO Finland
Lumbar epidural anesthesy
3.3
53.1
226
759
O36.5
ICD-10 Finland
Maternal care for poor fetal growth
268.0
51.4
52
*
LGA00
NOMESCO Finland
Sterilisation by ligature of Fallopian tubes
15.4
51.2
45
30
O33.8
ICD-10 Finland
Maternal care for disproportion of other origin
+∞
50.2
48
*
6500B
ICD-9 Finland
Delivery in a completely normal case[PARTUS SINE COMPLICATIONE]
0.3
48.9
119
3834
SPAT1196
SPAT
Monitoring of normal pregnancy
3.2
48.7
212
721
WX320
NOMESCO Finland
Spinalanesthesy
2.5
48.1
382
1777
Z34.9
ICD-10 Finland
Supervision of normal pregnancy, unspecified
2.5
47.3
368
1694
O35.8
ICD-10 Finland
Maternal care for other (suspected) fetal abnormality and damage
+∞
47.1
45
*
O46.9
ICD-10 Finland
Antepartum haemorrhage, unspecified
+∞
47.1
45
*
ZXD10
NOMESCO Finland
Scheduled procedure
2.1
46.7
736
4508
Z30.2
ICD-10 Finland
Sterilization
2.4
46.4
392
1872
Z32.1
ICD-10 Finland
Pregnancy confirmed
2.6
45.4
302
1289
Z39.2
ICD-10 Finland
Routine postpartum follow-up
2.4
42.2
333
1537
NE1AG
NOMESCO Finland
MRI pelvimetry with high intensity magnet
416.7
41.3
41
*
O61.0
ICD-10 Finland
Failed medical induction of labour
9.2
40.8
50
56
O36.8
ICD-10 Finland
Maternal care for other specified fetal problems
209.6
40.0
41
*
Z34.0
ICD-10 Finland
Supervision of normal first pregnancy
2.2
38.9
402
2074
MA2XE
NOMESCO Finland
Other obstetric ultrasound examination
2.7
37.7
232
948
O64.1
ICD-10 Finland
Obstructed labour due to breech presentation
10.5
36.1
40
39
O35.9
ICD-10 Finland
Maternal care for (suspected) fetal abnormality and damage, unspecified
+∞
34.5
33
*
Z35.4
ICD-10 Finland
Supervision of pregnancy with grand multiparity
9.3
34.0
41
45
O42.0
ICD-10 Finland
Premature rupture of membranes, onset of labour within 24 hours
+∞
33.4
32
*
O65.2
ICD-10 Finland
Obstructed labour due to pelvic inlet contraction
75.6
32.9
37
5
MCA96
NOMESCO Finland
Other caesarean section
35.8
32.9
42
12
MAC96
NOMESCO Finland
Other induction or advancement of labour
4.1
31.9
89
224
W84
ICPC
Pregnancy high risk
4.1
31.5
88
222
W92
ICPC
Compl labour/ delivery livebirth
6.9
30.2
47
70
Z36.4
ICD-10 Finland
Antenatal screening for fetal growth retardation using ultrasound and other physical methods
4.2
29.2
78
190
Z36.0
ICD-10 Finland
Antenatal screening for chromosomal anomalies
2.9
29.0
144
524
O20.0
ICD-10 Finland
Threatened abortion
3.5
28.7
100
294
O42.1
ICD-10 Finland
Premature rupture of membranes, onset of labour after 24 hours
+∞
28.2
27
*
O32.2
ICD-10 Finland
Maternal care for transverse and oblique lie
78.9
27.8
31
*
SPAT1197
SPAT
Extensive health check-up of expecting family
2.2
27.5
258
1266
O63.1
ICD-10 Finland
Prolonged second stage (of labour)
3.0
27.2
122
419
6534B
ICD-9 Finland
Disproportion, Foetopelvic disproportion[DISPROPORTIO FOETOPELVICA,SYNNYTYKSEN AIKANA]
7.1
27.2
41
59
MAB20
NOMESCO Finland
Failed external version
+∞
27.1
26
*
O13
ICD-10 Finland
Gestational [pregnancy-induced] hypertension
2.6
27.1
161
644
O47.9
ICD-10 Finland
False labour, unspecified
10.5
26.3
29
28
SPAT1379
SPAT
Health check-up of pregnant person
2.3
25.4
202
924
O41.1
ICD-10 Finland
Infection of amniotic sac and membranes
+∞
25.1
24
*
SPAT1357
SPAT
Monitoring of problem during pregnancy
3.9
24.4
74
198
MCA00
NOMESCO Finland
Upper uterine segment caesarean section
88.0
23.7
26
*
O86.0
ICD-10 Finland
Infection of obstetric surgical wound
6.4
23.6
39
62
O82.11
ICD-10 Finland
Childbirth with an emergency caesarean section in an emergency
6.8
22.5
35
52
J01DA01
ATC
[U] cefalexin
1.7
22.5
1202
9802
O36.9
ICD-10 Finland
Maternal care for fetal problem, unspecified
+∞
21.9
21
*
O68.0
ICD-10 Finland
Labour and delivery complicated by fetal heart rate anomaly
2.6
21.4
133
543
MA1AE
NOMESCO Finland
Ultrasound examination of early pregnancy (before 12. postmenstrual week)
2.0
21.0
276
1528
MBA03
NOMESCO Finland
Curettage of uterus after delivery or abortion
2.6
20.7
126
509
SPAT1380
SPAT
Postpartum check-up
2.3
20.6
165
756
O99.2
ICD-10 Finland
Endocrine, nutritional and metabolic diseases complicating pregnancy, childbirth and the puerperium
4.3
20.1
52
124
O32.0
ICD-10 Finland
Maternal care for unstable lie
+∞
19.8
19
*
O99.0
ICD-10 Finland
Anaemia complicating pregnancy, childbirth and the puerperium
5.9
19.7
35
60
OAB47, ,
SPAT
2.1
19.6
190
941
O34.1
ICD-10 Finland
Maternal care for tumour of corpus uteri
+∞
18.8
18
*
O99.5
ICD-10 Finland
Diseases of the respiratory system complicating pregnancy, childbirth and the puerperium
6.0
18.7
33
56
O84.2
ICD-10 Finland
Multiple delivery, all by caesarean section
191.9
18.6
19
*
A10AC01
ATC
insulin (human); parenteral
2.6
18.3
113
460
O66.5
ICD-10 Finland
Failed application of vacuum extractor and forceps, unspecified
17.8
18.3
28
16
O02.1
ICD-10 Finland
Missed abortion
2.1
18.2
178
883
SPAT1189
SPAT
Other ultrasound examination during pregnancy
3.4
18.0
66
201
O62.0
ICD-10 Finland
Primary inadequate contractions
7.7
17.8
25
33
O28.1
ICD-10 Finland
Abnormal biochemical finding on antenatal screening of mother
5.6
17.5
33
60
G03DA04
ATC
progesterone; systemic, rectal, vaginal
2.4
17.2
116
492
TMW99
NOMESCO Finland
Other minor surgical procedure in obstetrics
5.6
17.0
32
58
Z37.0
ICD-10 Finland
Single live birth
1.8
16.7
302
1839
O36.3
ICD-10 Finland
Maternal care for signs of fetal hypoxia
+∞
16.7
16
*
ZXE00
NOMESCO Finland
One hour or less
1.5
16.4
662
4925
SPAT1200
SPAT
Guidance for breast-feeding and breast care
3.4
16.2
57
169
O24.1
ICD-10 Finland
Diabetes mellitus in pregnancy: Pre-existing diabetes mellitus, non-insulin-dependent
6.2
15.9
27
44
O83.8
ICD-10 Finland
Other specified assisted single delivery
12.3
15.9
28
23
MAB10
NOMESCO Finland
External version
60.6
15.8
18
*
O36.4
ICD-10 Finland
Maternal care for intrauterine death
+∞
15.6
15
*
O41.8
ICD-10 Finland
Other specified disorders of amniotic fluid and membranes
+∞
15.6
15
*
O28.8
ICD-10 Finland
Other abnormal findings on antenatal screening of mother
5.3
15.2
30
57
MAW96
NOMESCO Finland
Other operation in pregnancy or at delivery
6.0
14.8
26
44
MA4AT
NOMESCO Finland
Chorion biopsy with ultrasound guidance
57.2
14.8
17
*
MA2JE
NOMESCO Finland
Ultrasound screening of fetal nuchal translucency
1.9
14.7
199
1108
ZXH09, ,
SPAT
2.7
14.6
76
284
O44.0
ICD-10 Finland
Placenta praevia specified as without haemorrhage
+∞
14.6
14
*
O80.0
ICD-10 Finland
Spontaneous vertex delivery
0.7
14.3
517
6863
WX602
NOMESCO Finland
Repeated or continuing anesthesia shots throug a catheter
2.0
14.2
166
878
J01CA08
ATC
pivmecillinam; oral
1.5
13.6
939
7695
Z36.9
ICD-10 Finland
Antenatal screening, unspecified
2.8
13.5
66
239
MAE20
NOMESCO Finland
Failed vacuum delivery
16.3
13.5
21
13
SPAT1317
SPAT
Planned health check-up monitoring, health check-up performed based on individual need
1.9
13.3
184
1031
O03.9
ICD-10 Finland
Spontaneous abortion, Complete or unspecified, without complication
2.1
13.2
130
646
A10AB01
ATC
insulin (human); parenteral
2.6
12.6
74
294
6441A
ICD-9 Finland
Early or threatened labour, Other threatened labour
+∞
12.5
12
*
O65.0
ICD-10 Finland
Obstructed labour due to deformed pelvis
130.9
12.4
13
*
ZXD00
NOMESCO Finland
Emergency procedure
2.9
12.0
56
198
6531A
ICD-9 Finland
Disproportion, Generally contracted pelvis[PELVIS ANGUSTA,RASKAUDEN AIKANA]
10.6
11.8
22
21
TAB22
NOMESCO Finland
Stoppin epidural fluid escape with coagulated blood
3.4
11.7
41
122
MAC10
NOMESCO Finland
Antepartum dilatation of cervical canal
3.9
11.7
34
89
6620B
ICD-9 Finland
Long labour, Prolonged first stage
5.6
11.7
22
40
O21.9
ICD-10 Finland
Vomiting of pregnancy, unspecified
4.2
11.5
30
72
H04AA01
ATC
glucagon; nasal, parenteral
2.8
11.5
55
197
O68.1
ICD-10 Finland
Labour and delivery complicated by meconium in amniotic fluid
5.1
11.5
24
48
O35.2
ICD-10 Finland
Maternal care for (suspected) hereditary disease in fetus
+∞
11.5
11
*
O44.1
ICD-10 Finland
Placenta praevia with haemorrhage
120.8
11.4
12
*
W78
ICPC
Pregnancy
1.6
11.4
258
1660
MBA00
NOMESCO Finland
Vacuum aspiration from uterus after delivery or abortion
2.4
11.4
80
347
O21.0
ICD-10 Finland
Mild hyperemesis gravidarum
3.8
11.2
33
87
O65.5
ICD-10 Finland
Obstructed labour due to abnormality of maternal pelvic organs
17.1
11.2
17
10
A10AB04
ATC
insulin lispro; parenteral
2.5
11.1
66
265
J01DB01
ATC
cefalexin; oral
1.5
10.9
1475
13420
NE1MA
NOMESCO Finland
Birth channel measurement with X-ray
60.4
10.6
12
*
G02CB01
ATC
bromocriptine; systemic
2.5
10.6
63
253
O20.9
ICD-10 Finland
Haemorrhage in early pregnancy, unspecified
2.5
10.5
67
278
TLC00
NOMESCO Finland
Insertion of intrauterine device
1.6
10.5
269
1785
O34.0
ICD-10 Finland
Maternal care for congenital malformation of uterus
+∞
10.4
10
*
G56.0
ICD-10 Finland
Carpal tunnel syndrome
1.6
10.4
260
1715
O99.89
ICD-10 Finland
Other specified diseases and conditions complicating pregnancy, childbirth and the puerperium
2.9
10.3
47
164
O02.0
ICD-10 Finland
Blighted ovum and nonhydatidiform mole
2.1
10.3
101
502
WX321
NOMESCO Finland
Acute spinal anesthesia for delivery
2.2
10.3
88
415
ZXH06, ,
SPAT
2.3
10.2
74
325
65000
ICD-8 Finland
Delivery without mention of complication, Occipital presentation
0.3
10.0
26
860
WX290
NOMESCO Finland
Other blockage of nerve
1.4
9.9
957
8128
O14.0
ICD-10 Finland
Mild to moderate pre-eclampsia
2.7
9.8
53
203
O82.9
ICD-10 Finland
Delivery by caesarean section, unspecified
55.3
9.7
11
*
Z12.4
ICD-10 Finland
Special screening examination for neoplasm of cervix
2.0
9.6
98
494
Z39.0
ICD-10 Finland
Care and examination immediately after delivery
4.0
9.6
27
69
SFA20
NOMESCO Finland
Two-surface restoration
1.4
9.5
1139
9982
Z35.0
ICD-10 Finland
Supervision of pregnancy with history of infertility
2.4
9.5
66
285
J01CA04
ATC
amoxicillin; systemic
1.5
9.4
1496
13759
O46.8
ICD-10 Finland
Other antepartum haemorrhage
+∞
9.4
9
*
O34.8
ICD-10 Finland
Maternal care for other abnormalities of pelvic organs
+∞
9.4
9
*
O36.0
ICD-10 Finland
Maternal care for rhesus isoimmunization
+∞
9.4
9
*
O33.7
ICD-10 Finland
Maternal care for disproportion due to other fetal deformities
+∞
9.4
9
*
Z35
ICD-10 Finland
Supervision of high-risk pregnancy
4.7
9.3
21
45
XMA00, ,
NOMESCO Finland
4.7
9.3
21
45
ZXE10
NOMESCO Finland
More than one and less than three hours
1.4
9.3
520
4029
E10.3
ICD-10 Finland
Type 1 diabetes mellitus, With ophthalmic complications
2.4
9.3
61
257
MAA96
NOMESCO Finland
Other intrauterine operation on pregnant uterus or fetus
13.7
9.2
15
11
O68.3
ICD-10 Finland
Labour and delivery complicated by biochemical evidence of fetal stress
4.3
9.1
23
54
W27
ICPC
Fear of complications of pregnancy
4.6
9.1
21
46
W29
ICPC
Pregnancy symptom/complaint other
2.7
9.0
49
188
6533A
ICD-9 Finland
Disproportion, Outlet contraction of pelvis[PELVIS ANGUSTA, ANOM APERT INFER,RASKAUDEN AIKANA]
15.7
9.0
14
9
N71.0
ICD-10 Finland
Acute inflammatory disease of uterus
2.1
9.0
84
410
2500B
ICD-9 Finland
Diabetes mellitus without mention of complication[DIABETES MELLITUS SINE COMPLICATIONE ,TYYPPI I]
2.6
9.0
52
206
O26.88
ICD-10 Finland
Other specified pregnancy-related conditions
3.7
9.0
28
77
Z3232
NOMESCO Finland
Midwife
1.6
8.9
225
1484
WX600
NOMESCO Finland
Single shot through catheter
2.8
8.9
42
150
O26.82
ICD-10 Finland
Exhaustion and fatigue pregnancy-related
3.0
8.8
39
134
O99.3
ICD-10 Finland
Mental disorders and diseases of the nervous system complicating pregnancy, childbirth and the puerperium
2.8
8.7
41
146
LC2BE
NOMESCO Finland
Transvaginal ultrasound examination of uterus, parametria and lower abdomen
1.3
8.6
778
6488
V252A
ICD-9 Finland
Contraceptive management, Sterilisation
0.1
8.6
*
275
E10.9
ICD-10 Finland
Type 1 diabetes mellitus, Without complications
2.1
8.6
78
377
A10AA01, ,
ATC
2.4
8.6
57
242
65400
ICD-8 Finland
Occipital presentation
7.0
8.5
20
29
O28.3
ICD-10 Finland
Abnormal ultrasonic finding on antenatal screening of mother
9.0
8.5
17
19
LCA16
NOMESCO Finland
Destruction of endometrium
2.4
8.5
55
230
6601B
ICD-9 Finland
Obstructed labour, Obstruction by bony pelvis
10.1
8.5
16
16
SPAT1391
SPAT
Counselling and guidance related to family situation
3.8
8.5
25
66
O62.1
ICD-10 Finland
Secondary uterine inertia
3.5
8.5
29
85
O85
ICD-10 Finland
Puerperal sepsis
3.5
8.5
29
85
SPAT1028
SPAT
Ultrasound examination of paranasal sinuses
1.9
8.5
115
640
O91.2
ICD-10 Finland
Nonpurulent mastitis associated with childbirth
3.6
8.4
27
76
O64.8
ICD-10 Finland
Obstructed labour due to other malposition and malpresentation
4.9
8.4
18
37
O34.3
ICD-10 Finland
Maternal care for cervical incompetence
+∞
8.3
8
*
6581A
ICD-9 Finland
Other problems associated with amniotic cavity and membranes, Premature rupture of membranes
+∞
8.3
8
*
G02BA03
ATC
plastic IUD with progestogen
1.4
8.3
483
3755
6532B
ICD-9 Finland
Disproportion, Inlet contraction of pelvis[PELVIS ANGUSTA, ANOM APERT SUPER,SYNNYTYKSEN AIKANA]
10.8
8.3
15
14
6534A
ICD-9 Finland
Disproportion, Foetopelvic disproportion[DISPROPORTIO FOETOPELVICA,RASKAUDEN AIKANA]
10.8
8.3
15
14
O10.0
ICD-10 Finland
Pre-existing essential hypertension complicating pregnancy, childbirth and the puerperium
2.5
8.3
51
209
Z31.5
ICD-10 Finland
Genetic counselling
1.8
8.3
118
668
Z32.0
ICD-10 Finland
Pregnancy, not (yet) confirmed
2.4
8.2
56
240
A10AE05
ATC
insulin detemir; parenteral
2.2
8.2
70
330
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
1.4
8.0
524
4148
O03.6
ICD-10 Finland
Spontaneous abortion, Complete or unspecified, complicated by delayed or excessive haemorrhage
3.5
8.0
26
74
QBJ30
NOMESCO Finland
Correction of abdominal apron
3.2
8.0
31
99
R21
ICPC
Throat symptom/complaint
1.4
7.9
431
3309
Z35.1
ICD-10 Finland
Supervision of pregnancy with history of abortive outcome
7.8
7.9
17
22
A10AA02, ,
ATC
2.3
7.9
55
239
O81.4
ICD-10 Finland
Vacuum extractor delivery
1.7
7.7
154
959
SPAT1263
SPAT
Sampling
1.3
7.7
620
5062
R3110
NOMESCO Finland
Psychosocial training
2.8
7.7
37
134
O68.2
ICD-10 Finland
Labour and delivery complicated by fetal heart rate anomaly with meconium in amniotic fluid
3.6
7.6
24
67
O66.4
ICD-10 Finland
Failed trial of labour, unspecified
25.1
7.6
10
*
WX110
NOMESCO Finland
Infiltration anesthesia
1.3
7.6
1284
11644
A10AB05
ATC
insulin aspart; parenteral
1.9
7.5
86
454
SPAT1187
SPAT
General ultrasound examination in early pregnancy
3.9
7.4
21
54
O26.9
ICD-10 Finland
Pregnancy-related condition, unspecified
4.4
7.4
18
41
6582B
ICD-9 Finland
Other problems associated with amniotic cavity and membranes, Delayed delivery after spontaneous or unspecified rupture of membranes
+∞
7.3
7
*
N02BE01
ATC
paracetamol; systemic, rectal
1.4
7.3
1532
14323
MAC01
NOMESCO Finland
Rupture of aminiotic membrane for induction of labor
3.2
7.1
27
85
R09
ICPC
Sinus symptom/complaint
1.6
7.1
176
1155
WW200, ,
SPAT
1.4
7.0
316
2346
O03.1
ICD-10 Finland
Spontaneous abortion, Incomplete, complicated by delayed or excessive haemorrhage
2.4
7.0
46
195
SPAT1192
SPAT
Gynaecological examination
1.5
7.0
242
1709
ACC51
NOMESCO Finland
Release of median nerve
1.7
6.9
135
835
W85
ICPC
Gestational diabetes
2.1
6.9
67
333
W30
ICPC
Pregnancy, Medical examin/health eval complete
5.9
6.9
18
31
O66.2
ICD-10 Finland
Obstructed labour due to unusually large fetus
8.3
6.8
14
17
SPAT1262
SPAT
Handing over of treatment supplies
1.6
6.8
156
1007
TLC02
NOMESCO Finland
Simple extraction of IUD
1.6
6.7
147
937
O99.1
ICD-10 Finland
Other diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism complicating pregnancy, childbirth and the puerperium
3.9
6.7
19
49
G01AF05
ATC
econazole; vaginal
1.5
6.7
221
1545
O00.1
ICD-10 Finland
Tubal pregnancy
2.2
6.7
53
244
215
Kela drug reimbursment
Diabetes, non-insulin-treated
1.5
6.7
228
1606
SPAT1190
SPAT
Insertion or removal of intrauterine contraceptive device
1.6
6.6
164
1076
Z87.5
ICD-10 Finland
Personal history of complications of pregnancy, childbirth and the puerperium
5.5
6.6
18
33
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.3
6.5
653
5466
G03GB02
ATC
clomifene; oral
1.9
6.5
75
397
MAC00
NOMESCO Finland
Rupture of amniotic membrane
5.3
6.5
18
34
O72.1
ICD-10 Finland
Other immediate postpartum haemorrhage
2.2
6.4
53
248
103
Kela drug reimbursment
Diabetes, insulin-treated
1.5
6.4
228
1618
O14.9
ICD-10 Finland
Pre-eclampsia, unspecified
2.8
6.4
31
113
O26.6
ICD-10 Finland
Liver disorders in pregnancy, childbirth and the puerperium
2.4
6.4
40
166
112
Kela drug reimbursment
Severe psychotic and other severe mental disorders
0.4
6.4
41
892
SAA01
NOMESCO Finland
Simple examination of mouth
1.3
6.3
1343
12379
6450B
ICD-9 Finland
Prolonged pregnancy[GRAVIDITAS PROLANGATA CUM PARTU]
+∞
6.3
6
*
O34.4
ICD-10 Finland
Maternal care for other abnormalities of cervix
+∞
6.3
6
*
O36.2
ICD-10 Finland
Maternal care for hydrops fetalis
+∞
6.3
6
*
6584B
ICD-9 Finland
Other problems associated with amniotic cavity and membranes, Infection of amniotic cavity[AMNIONITIS, SYNNYTYKSEN AIKANA]
+∞
6.3
6
*
O41.9
ICD-10 Finland
Disorder of amniotic fluid and membranes, unspecified
+∞
6.3
6
*
O45.9
ICD-10 Finland
Premature separation of placenta, unspecified
+∞
6.3
6
*
O32.4
ICD-10 Finland
Maternal care for high head at term
+∞
6.3
6
*
O35.5
ICD-10 Finland
Maternal care for (suspected) damage to fetus by drugs
+∞
6.3
6
*
O34.9
ICD-10 Finland
Maternal care for abnormality of pelvic organ, unspecified
+∞
6.3
6
*
SPAT1324
SPAT
Screening procedure
1.3
6.2
590
4902
MWE00
NOMESCO Finland
Reoperation for deep haemorrhage in obstetric surgery
12.6
6.1
10
8
J01.0
ICD-10 Finland
Acute maxillary sinusitis
1.3
6.1
524
4292
SPAT1236
SPAT
Informing family of child’s disability
2.8
6.1
29
105
SPAT1301
SPAT
No procedures
1.4
6.1
369
2874

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
406
2841
1.55
12.72
3.5
3.0
1.02
1.01
kg/l
0.68
70
373
105
539
2.01
9.82
1.5
1.3
—
—
—
0
0
57
228
2.55
9.66
1.3
1.3
6.64
7.21
mmol/l
1.04
52
210
1011
8746
1.35
8.89
3.5
3.4
72.83
784.75
e6/l
2.80
12
91
247
1705
1.52
7.98
1.8
1.7
—
—
—
0
0
85
446
1.95
7.53
7.3
6.8
—
—
—
0
0
417
3290
1.35
6.31
2.0
2.2
—
—
—
0
0
41
179
2.32
5.87
2.1
1.8
5.08
5.07
umol/l
0.00
33
128
1569
14887
1.39
5.46
8.2
9.1
3.89
3.90
mmol/l
0.46
1529
14502
1563
14826
1.38
5.40
8.1
9.0
139.62
139.60
mmol/l
0.22
1526
14481
1709
16507
1.56
5.11
8.9
8.8
—
—
—
0
0
1566
14894
1.36
5.02
5.0
4.9
1.67
2.03
mu/l
1.17
1512
14338
243
1851
1.36
4.55
2.4
2.8
32.42
476.47
ng/l
2.89
111
902
1795
17621
2.22
4.42
14.2
14.8
6.58
6.56
e9/l
0.13
1774
17316
1794
17618
2.15
4.23
14.1
14.8
4.50
4.49
e12/l
0.46
1773
17333
63
1043
0.59
4.17
3.4
4.3
0.43
0.73
%
1.00
21
283
1792
17599
2.07
4.09
14.2
14.8
273.75
275.92
e9/l
0.86
1775
17323
64
1045
0.60
4.02
3.7
4.6
0.07
0.78
%
0.79
15
233
477
4044
1.24
3.93
1.8
1.9
—
—
—
0
0
1028
9427
1.21
3.82
3.5
3.6
—
—
—
0
0
1403
13273
1.25
3.82
4.3
4.3
14.10
14.16
pmol/l
0.45
1361
12666
5
207
0.24
3.81
19.8
17.2
1453.80
6195.68
nmol/l
—
5
200
5
202
0.25
3.67
12.0
12.1
833.80
916.08
nmol/l
—
5
197
342
4112
0.79
3.65
1.7
1.4
—
—
—
0
0
185
1402
1.36
3.60
1.1
1.1
—
—
—
0
0
288
2323
1.28
3.60
2.1
2.3
7.31
8.88
e6/l
1.12
254
2079
470
4017
1.23
3.55
2.0
2.5
53.85
55.42
u/l
0.43
450
3782
70
1077
0.64
3.45
3.7
4.7
0.22
0.11
%
0.41
18
266
350
2913
1.25
3.36
3.4
3.0
—
—
—
0
0
1691
16441
1.39
3.36
8.2
8.3
24.90
24.25
u/l
0.76
1670
16122
454
3887
1.22
3.35
1.9
2.3
16.24
25.82
ng/l
0.72
158
1444
756
6799
1.19
3.30
3.2
3.7
6.50
6.29
mmol/l
1.46
691
6373
1785
17558
1.80
3.27
14.0
14.7
39.90
40.36
%
0.94
1698
16911
398
3373
1.23
3.23
2.4
2.7
44.31
103.95
e6/l
1.10
306
2526
366
3082
1.23
3.15
2.2
2.5
—
—
—
0
0
76
1124
0.66
3.13
3.6
4.5
1.17
0.90
%
0.46
24
314
761
6876
1.18
3.09
4.3
4.1
0.01
0.00
estimate
0.40
98
1272
932
8571
1.18
3.05
3.2
2.9
59.87
68.44
ug/l
3.39
898
8254
634
5652
1.19
2.99
3.0
2.7
5.84
5.87
ph
0.12
83
773
76
1111
0.67
2.97
1.5
1.4
—
—
—
0
0
766
6945
1.18
2.95
3.2
3.0
0.00
0.01
estimate
1.30
99
1235
1368
13019
1.20
2.94
4.5
4.0
38.48
37.42
mmol/mol
4.04
1325
12501
10
27
3.72
2.88
1.1
1.5
—
—
—
0
0
375
3202
1.22
2.81
1.8
2.0
172.06
145.92
u/l
0.24
361
3071
757
6879
1.17
2.79
3.2
3.0
0.00
0.00
estimate
0.50
102
1302
51
316
1.63
2.77
3.9
4.7
1.31
1.22
mmol/l
0.29
46
281
359
3056
1.22
2.77
2.3
2.6
0.16
0.30
e6/l
2.53
270
2233
1601
15514
1.26
2.71
3.9
3.6
3.04
3.00
mmol/l
1.07
1553
14954
387
3329
1.21
2.68
1.4
1.3
8.17
8.96
u/ml
0.09
164
1498
8
19
4.22
2.68
2.3
1.8
—
—
—
0
0
1591
15413
1.25
2.65
3.7
3.4
4.92
4.95
mmol/l
0.79
1557
14933
22
427
0.51
2.63
2.4
1.3
5.52
2.79
ug/l
0.42
16
365
408
3534
1.20
2.62
1.6
1.7
0.72
0.67
mg/l
0.17
300
2639
59
883
0.66
2.62
3.2
3.2
1.23
1.23
mmol/l
0.24
54
788
38
223
1.72
2.55
1.2
1.1
15.00
1482.48
iu/ml
—
7
52
1585
15361
1.24
2.55
3.6
3.4
1.50
1.55
mmol/l
7.77
1546
14852
335
2859
1.21
2.52
1.7
1.6
—
—
—
0
0
695
6312
1.16
2.52
2.2
2.2
—
—
—
0
0
302
2554
1.22
2.49
3.7
3.6
2.10
7.73
mg/mmol
7.35
191
1575
260
2172
1.23
2.41
2.2
2.5
539.27
523.56
mosm/kgh2o
0.48
222
1859
7
191
0.36
2.41
3.0
2.9
—
—
—
0
0
630
5698
1.16
2.38
4.7
5.5
1.22
1.22
mmol/l
0.13
563
4892
114
860
1.35
2.36
3.5
3.2
—
—
—
0
0
1119
10557
1.16
2.35
5.9
6.7
70.39
72.29
u/l
1.04
1070
10082
398
3475
1.19
2.33
1.4
1.3
20.31
22.59
iu/ml
0.16
143
1146
1489
14374
1.20
2.30
3.4
3.4
5.67
5.60
mmol/l
1.21
1431
13750
342
2954
1.19
2.26
1.7
1.9
—
—
—
0
0
1584
15395
1.22
2.19
9.2
9.8
18.47
17.69
mg/l
0.40
1237
11558
995
9348
1.14
2.11
2.4
2.6
—
—
—
0
0
187
1531
1.25
2.11
1.5
1.6
—
—
—
0
0
218
1816
1.23
2.10
1.8
2.2
2.83
1.16
e6/l
0.37
125
959
7
20
3.51
2.05
2.4
1.8
—
—
—
0
0
7
175
0.40
2.03
1.0
1.3
46.24
29.63
nmol/l
—
7
151
288
2474
1.19
2.02
3.3
3.1
262.55
579.43
mg/l
0.60
182
1478
8
26
3.09
2.01
3.9
1.9
—
—
—
0
0
1663
16272
1.25
1.98
9.4
10.1
64.64
66.09
umol/l
1.98
1663
16267
390
3446
1.17
1.96
1.7
1.6
1.36
1.36
mmol/l
0.00
353
3083
477
4286
1.15
1.92
2.7
3.1
62.08
56.07
e6/l
0.12
339
2818
13
58
2.25
1.91
1.4
1.2
—
—
—
0
0
43
283
1.53
1.90
1.6
1.8
—
—
—
0
0
82
612
1.36
1.87
1.1
1.1
3.14
4.29
u/ml
0.20
17
117
463
4158
1.15
1.87
1.3
1.3
1.20
1.35
u/ml
0.22
134
1219
64
461
1.40
1.82
2.0
2.8
—
—
—
0
0
723
6701
1.13
1.81
4.9
5.5
9.70
9.35
umol/l
0.69
682
6356
22
123
1.80
1.80
2.3
2.3
—
—
—
0
0
1424
13775
1.15
1.78
11.0
12.0
14.19
14.23
%
0.10
1405
13572
105
820
1.30
1.77
2.6
2.1
—
—
—
0
0
28
169
1.67
1.77
2.3
2.4
5.07
126.21
ug/min
2.75
15
115
226
1924
1.20
1.77
1.6
1.5
—
—
—
0
0
559
5128
1.13
1.62
4.2
4.3
37.38
37.10
g/l
0.74
536
4844
48
336
1.44
1.62
3.9
4.4
1.65
1.77
%
0.30
43
318
9
187
0.48
1.62
1.0
1.4
—
—
—
0
0
16
84
1.91
1.59
1.6
1.8
132.13
129.68
nmol/l
0.09
16
84
7
26
2.70
1.58
1.0
1.2
—
—
—
0
0
57
417
1.38
1.52
2.3
2.3
13.14
13.19
%
0.17
57
411
23
140
1.65
1.45
1.0
1.0
—
—
—
0
0
114
928
1.24
1.42
1.1
1.1
—
—
—
0
0
295
2620
1.15
1.40
1.3
1.3
31.80
30.74
iu/l
0.21
273
2294
93
741
1.27
1.40
1.2
1.3
—
—
—
0
0
150
1262
1.21
1.37
4.4
5.6
1.07
1.03
mmol/l
1.35
143
1205
185
1589
1.18
1.35
3.2
2.4
4.57
5.67
umol/l
1.70
162
1341
119
980
1.23
1.35
1.1
1.1
—
—
—
0
0
56
741
0.75
1.35
1.3
1.4
31.48
28.60
u/l
0.31
48
612
1164
11199
1.11
1.34
3.7
3.7
8.86
9.40
mm/h
1.26
1110
10646
540
4997
1.11
1.33
4.0
4.7
1.22
1.22
mmol/l
0.37
509
4682
1519
14841
1.14
1.32
3.3
3.1
1.23
1.21
mmol/l
0.56
1477
14306
23
356
0.64
1.32
1.2
1.3
360.58
313.33
ug/g
0.41
12
178
7
147
0.47
1.32
2.9
3.6
32.19
292.93
u/ml
—
7
139
28
185
1.52
1.29
1.0
1.0
1.44
0.41
u/ml
—
10
43
10
48
2.09
1.27
1.0
1.0
—
—
—
0
0
10
48
2.09
1.27
1.0
1.0
—
—
—
0
0
10
48
2.09
1.27
1.0
1.0
—
—
—
0
0
9
44
2.05
1.27
1.4
1.6
—
—
—
0
0
606
6466
0.91
1.21
6.3
7.9
0.00
0.00
e9/l
0.57
477
5306
8
38
2.11
1.18
5.1
4.9
—
—
—
0
0
280
2513
1.13
1.16
1.4
1.5
32422302.79
41363064.80
pmol/l
0.10
256
2275
378
3455
1.12
1.16
3.7
3.2
0.02
0.00
estimate
0.42
97
1261
333
3022
1.12
1.15
3.1
3.0
8.42
7.63
mmol/l
2.09
301
2702
72
572
1.27
1.15
1.7
1.6
—
—
—
0
0
266
2382
1.14
1.14
2.7
3.9
—
—
—
0
0
11
58
1.90
1.12
3.1
3.8
242.60
208.47
umol/l
—
5
36
567
5304
1.10
1.11
3.5
3.0
28.46
28.11
u/l
0.09
547
5083
21
317
0.66
1.11
3.1
3.6
3.80
3.95
e9/l
0.16
21
317
191
1678
1.15
1.09
1.7
1.7
1189.31
1196.59
nmol/l
0.04
168
1361
60
470
1.29
1.08
3.8
4.5
—
—
—
0
0
507
4725
1.10
1.07
1.8
1.7
101.42
101.36
pmol/l
0.01
270
2583
25
169
1.49
1.07
1.0
1.0
0.56
0.20
u/ml
—
7
37
22
326
0.67
1.07
3.0
3.7
55.77
57.04
%
0.33
22
326
194
1710
1.15
1.06
1.9
2.4
4.50
4.72
e6/l
0.10
105
864
6
124
0.48
1.05
2.3
3.1
2.52
2.95
nmol/l
—
6
116
12
67
1.80
1.04
1.4
1.1
—
—
—
0
0
34
246
1.39
1.04
4.4
3.1
18.56
20.63
mg/l
0.21
23
155
8
147
0.54
1.03
1.3
2.6
—
—
—
0
0
17
106
1.61
1.03
3.9
2.4
—
—
—
0
0
21
311
0.67
1.02
3.6
3.0
1.50
1.30
mg/l
0.36
21
301
7
132
0.53
0.99
1.4
3.0
—
—
—
0
0
460
4286
1.10
0.98
2.9
3.4
2.32
2.34
mmol/l
3.09
423
3970
223
2000
1.13
0.96
2.1
2.4
2.38
2.41
mmol/l
2.97
192
1771
364
3359
1.10
0.94
2.1
2.2
2.36
2.71
mg/l
4.04
322
2935
21
142
1.48
0.92
2.1
2.2
4.94
5.27
u/ml
0.07
21
142
6
28
2.15
0.91
1.2
1.3
34.97
36.54
%
—
6
22
137
1193
1.16
0.91
1.2
1.2
—
—
—
0
0
446
4167
1.09
0.90
2.5
2.6
—
—
—
0
0
6
29
2.07
0.89
1.2
1.0
—
—
—
0
0
351
3244
1.10
0.89
1.8
2.0
291.36
2091.51
umol/l
4.70
320
2998
8
42
1.91
0.88
5.4
2.5
—
—
—
0
0
7
131
0.53
0.87
1.0
1.2
—
—
—
0
0
90
1061
0.84
0.87
3.4
2.2
0.21
0.23
g/l
1.94
85
1008
138
1210
1.15
0.85
2.1
1.9
3915.92
2476.86
u/l
0.28
46
391
32
423
0.75
0.84
5.0
8.9
23.29
24.14
mmol/l
1.08
32
416
93
1089
0.85
0.84
3.0
3.2
—
—
—
0
0
26
188
1.39
0.83
1.3
1.2
—
—
—
0
0
12
190
0.63
0.83
2.4
2.8
1.70
2.26
mmol/l
—
5
129
38
488
0.77
0.82
1.3
1.3
62.55
27.81
u/ml
—
6
52
92
1074
0.85
0.81
1.2
1.2
—
—
—
0
0
91
1063
0.85
0.80
1.5
1.7
323.35
339.86
mu/l
0.08
85
940
20
282
0.71
0.79
1.2
1.2
—
—
—
0
0
0
25
0.00
0.79
0.0
1.2
—
316.38
—
0
5
0
26
0.00
0.78
0.0
1.4
—
—
—
0
0
133
1504
0.88
0.77
1.3
1.3
—
—
—
0
0
10
59
1.70
0.75
1.5
1.8
—
—
—
0
0
133
1177
1.14
0.74
1.3
1.2
27.60
39.55
au/ml
—
10
54
12
184
0.65
0.73
1.1
1.1
—
—
—
0
0
19
133
1.43
0.73
1.2
1.1
451.47
426.55
nmol/l
0.21
19
127
258
2375
1.10
0.73
1.4
1.5
20.69
20.53
nmol/l
0.08
241
2179
9
56
1.61
0.72
1.2
2.6
—
—
—
0
0
7
40
1.75
0.71
1.6
1.5
—
—
—
0
0
677
6490
1.07
0.70
2.5
2.3
74.81
74.26
nmol/l
0.22
643
6157
57
473
1.21
0.69
1.0
1.1
3.48
4.65
u/ml
0.26
24
233
19
135
1.41
0.69
1.1
1.2
1.02
1.02
ratio
—
6
47
24
180
1.34
0.65
2.5
2.5
—
—
—
0
0
12
178
0.67
0.65
1.7
1.6
—
—
—
0
0
112
992
1.14
0.64
1.2
1.1
47.00
95.59
titre
—
5
32
83
720
1.16
0.63
2.1
3.5
1.98
1.80
mmol/l
0.18
61
604
8
49
1.64
0.62
1.0
1.4
—
—
—
0
0
0
20
0.00
0.60
0.0
1.0
—
0.11
—
0
9
0
20
0.00
0.60
0.0
1.0
—
—
—
0
0
398
3767
1.07
0.60
5.7
7.2
—
—
—
0
0
12
80
1.50
0.59
2.0
4.5
—
—
—
0
0
52
436
1.20
0.59
5.6
8.9
—
—
—
0
0
53
447
1.19
0.57
1.0
1.1
1.38
0.86
u/ml
0.49
18
172
290
2718
1.08
0.57
1.4
1.4
575.38
541.60
titre
0.09
52
561
14
98
1.43
0.56
1.1
1.1
—
—
—
0
0
87
985
0.88
0.56
3.7
3.6
2.70
44.46
ug/l
0.58
65
692
10
65
1.54
0.55
1.1
1.1
—
—
—
0
0
12
82
1.47
0.54
1.8
1.7
3.86
2.72
u/field
—
7
46
26
328
0.79
0.54
1.4
1.2
188.53
267.73
u/ml
1.36
17
223
9
61
1.48
0.53
1.1
1.1
—
—
—
0
0
23
294
0.78
0.53
2.7
1.9
5.21
5.42
mmol/24h
0.13
23
273
206
1911
1.09
0.53
1.2
1.2
—
—
—
0
0
6
40
1.50
0.51
1.0
1.2
—
—
—
0
0
6
40
1.50
0.51
1.0
1.0
—
—
—
0
0
13
180
0.72
0.51
1.0
1.4
—
—
—
0
0
140
1280
1.10
0.50
2.3
2.2
35.49
28.50
au/ml
—
10
139
17
127
1.34
0.49
1.2
1.3
—
—
—
0
0
12
167
0.72
0.49
2.9
4.1
22.50
28.08
u/ml
0.19
12
167
74
837
0.88
0.49
1.2
1.3
0.40
1.58
u/ml
1.37
13
76
18
137
1.32
0.47
1.1
1.1
—
—
—
0
0
19
146
1.30
0.47
1.6
1.7
—
—
—
0
0
41
483
0.85
0.46
1.1
1.1
—
—
—
0
0
732
7533
0.95
0.46
5.1
6.0
29.49
29.78
%
0.35
673
7172
5
84
0.59
0.45
1.0
1.3
161.60
154.75
mmol/24h
—
5
84
60
525
1.15
0.45
1.1
1.1
1.02
2.24
u/ml
0.98
27
235
175
1627
1.08
0.45
1.3
1.5
—
—
—
0
0
14
186
0.75
0.44
1.0
1.4
—
—
—
0
0
210
1968
1.08
0.44
1.9
2.3
14.11
14.47
umol/l
0.35
203
1871
43
367
1.18
0.44
3.3
2.3
—
—
—
0
0
185
1726
1.08
0.43
1.3
1.4
—
—
—
0
0
53
607
0.87
0.43
1.7
2.7
75.96
72.93
e9/l
0.20
39
456
6
92
0.65
0.42
2.8
3.6
—
—
—
0
0
6
94
0.64
0.42
5.2
7.5
14.25
11.07
mg/l
—
6
89
228
2418
0.93
0.42
2.4
2.4
107.40
99.63
ug/g
0.11
191
1909
8
57
1.41
0.42
1.0
1.1
—
—
—
0
0
18
228
0.79
0.41
1.3
1.1
—
—
—
0
0
0
15
0.00
0.41
0.0
3.9
—
—
—
0
0
0
15
0.00
0.41
0.0
1.9
—
23.80
—
0
15
0
15
0.00
0.41
0.0
2.1
—
—
—
0
0
0
17
0.00
0.40
0.0
1.0
—
—
—
0
0
357
3416
1.06
0.40
3.4
3.6
7.40
7.40
ph
0.03
42
653
23
186
1.24
0.40
1.0
1.1
0.34
0.38
u/ml
—
9
58
187
1754
1.07
0.39
1.9
2.6
622.99
386.04
ng/l
0.32
148
1421
122
1322
0.92
0.39
3.6
3.2
31.57
32.14
%
0.25
100
1042
35
297
1.18
0.39
2.7
4.5
—
—
—
0
0
0
19
0.00
0.39
0.0
1.2
—
—
—
0
0
699
7175
0.96
0.39
5.2
6.3
—
—
—
0
0
158
1475
1.08
0.38
2.6
2.4
27.18
34.37
u/ml
0.89
152
1429
373
3580
1.05
0.38
1.3
1.4
2.12
2.10
g/l
0.15
242
2416
272
2857
0.94
0.38
2.1
2.5
—
—
—
0
0
726
7443
0.96
0.38
5.0
5.8
56.69
56.39
%
0.34
668
7077
23
188
1.23
0.37
1.0
1.1
—
—
—
0
0
23
279
0.82
0.37
1.1
1.2
7.64
2.85
u/ml
0.60
11
106
350
3356
1.05
0.37
3.7
3.3
100.05
100.06
%
0.00
341
3255
64
572
1.12
0.37
2.4
2.1
—
—
—
0
0
8
113
0.71
0.37
1.5
1.8
—
—
—
0
0
66
734
0.90
0.36
1.6
1.7
—
—
—
0
0
703
7206
0.96
0.36
5.1
6.0
2.74
2.76
%
0.09
646
6827
11
146
0.75
0.36
13.8
12.6
0.55
0.65
mmol/l
0.79
11
131
9
126
0.71
0.35
1.6
1.3
7.93
9.70
umol/l
—
9
117
82
898
0.91
0.34
1.5
1.9
1.36
1.34
g/l
0.08
77
841
30
255
1.18
0.34
1.2
1.1
—
—
—
0
0
708
7246
0.96
0.33
5.2
6.3
7.74
7.88
%
0.72
653
6883
15
118
1.27
0.33
2.6
1.3
—
—
—
0
0
6
46
1.31
0.33
1.3
1.3
—
—
—
0
0
10
74
1.35
0.32
5.8
2.7
—
—
—
0
0
22
263
0.83
0.32
2.5
3.9
1.31
1.26
mmol/l
0.10
22
257
10
132
0.76
0.32
1.2
1.1
—
—
—
0
0
53
591
0.89
0.32
1.3
1.2
—
—
—
0
0
12
92
1.31
0.31
1.0
1.1
—
7.21
—
0
19
13
101
1.29
0.31
1.5
1.8
—
—
—
0
0
751
7669
0.96
0.31
5.1
6.0
0.51
0.52
e9/l
0.86
655
6887
106
984
1.08
0.31
3.6
3.4
—
—
—
0
0
158
1675
0.94
0.31
1.4
1.4
—
—
—
0
0
7
54
1.30
0.30
1.4
1.6
—
—
—
0
0
697
7122
0.97
0.30
2.1
2.2
—
—
—
0
0
753
7681
0.97
0.29
5.1
6.0
0.04
0.04
e9/l
0.60
652
6879
19
228
0.83
0.29
2.0
1.6
—
—
—
0
0
8
106
0.75
0.29
2.9
2.9
—
—
—
0
0
14
112
1.25
0.28
1.2
1.6
53.43
68.31
mmol/l
—
7
91
211
2208
0.95
0.28
1.6
1.6
—
—
—
0
0
682
6963
0.97
0.28
5.2
6.1
0.66
0.69
%
1.27
623
6550
12
94
1.28
0.28
1.7
1.7
52.24
37.40
%
0.90
12
52
49
441
1.11
0.28
1.2
1.3
108.00
93.26
titre
—
5
46
9
120
0.75
0.27
1.1
1.3
—
—
—
0
0
200
1910
1.05
0.27
1.6
1.8
—
—
—
0
0
11
139
0.79
0.27
1.0
1.2
—
—
—
0
0
171
1795
0.95
0.26
1.2
1.2
134.09
153.52
iu/ml
0.36
75
763
5
71
0.70
0.26
1.0
1.2
—
—
—
0
0
9
72
1.25
0.25
1.0
1.1
—
—
—
0
0
9
73
1.23
0.25
1.1
1.2
167.89
254.79
u/l
—
9
63
50
454
1.10
0.25
1.4
1.3
—
—
—
0
0
28
319
0.88
0.25
1.7
1.6
—
—
—
0
0
135
1424
0.94
0.25
1.4
1.5
—
—
—
0
0
785
7982
0.97
0.24
5.2
6.4
0.18
0.18
e9/l
0.21
719
7255
103
968
1.07
0.24
1.3
1.4
203.44
222.60
miu/ml
0.21
45
500
63
683
0.92
0.24
1.7
2.0
—
—
—
0
0
124
1309
0.94
0.24
2.2
2.3
28.21
39.04
u/l
3.01
107
1120
50
456
1.10
0.23
1.4
1.3
—
—
—
0
0
61
659
0.92
0.22
4.0
8.2
—
—
—
0
0
12
146
0.82
0.22
1.1
1.3
1.60
1.59
g/l
0.07
12
146
393
3830
1.03
0.22
1.8
1.8
—
—
—
0
0
92
866
1.07
0.21
1.4
1.4
—
—
—
0
0
0
11
0.00
0.21
0.0
2.5
—
2.67
—
0
11
0
11
0.00
0.21
0.0
3.2
—
—
—
0
0
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
0
10
0.00
0.21
0.0
2.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
4.7
—
—
—
0
0
304
2952
1.04
0.21
1.4
1.3
—
—
—
0
0
31
277
1.12
0.21
1.1
1.0
—
—
—
0
0
0
12
0.00
0.21
0.0
1.5
—
39.45
—
0
12
0
12
0.00
0.21
0.0
1.0
—
0.10
—
0
5
0
12
0.00
0.21
0.0
1.0
—
—
—
0
0
0
12
0.00
0.21
0.0
1.2
—
—
—
0
0
0
12
0.00
0.21
0.0
1.0
—
—
—
0
0
0
12
0.00
0.21
0.0
1.1
—
0.10
—
0
7
0
12
0.00
0.21
0.0
1.2
—
—
—
0
0
5
43
1.16
0.21
1.0
1.2
0.08
0.05
u/ml
—
5
43
20
173
1.16
0.21
1.3
1.2
—
—
—
0
0
22
251
0.87
0.21
4.0
4.7
30.93
114.76
u/ml
—
10
76
0
13
0.00
0.21
0.0
1.3
—
—
—
0
0
0
13
0.00
0.21
0.0
1.3
—
260.05
—
0
13
11
134
0.82
0.20
1.0
1.1
—
—
—
0
0
0
14
0.00
0.20
0.0
2.7
—
—
—
0
0
0
14
0.00
0.20
0.0
1.9
—
2.07
—
0
14
0
14
0.00
0.20
0.0
4.1
—
—
—
0
0
9
112
0.80
0.20
1.1
1.1
—
—
—
0
0
31
344
0.90
0.19
2.5
2.8
—
—
—
0
0
127
1215
1.05
0.18
2.6
2.4
3.89
4.64
e9/l
1.22
114
1072
14
164
0.85
0.18
1.4
2.4
—
—
—
0
0
58
541
1.07
0.18
1.1
1.2
—
—
—
0
0
7
59
1.19
0.18
1.7
2.2
13.61
11.30
%
—
7
59
50
538
0.93
0.18
1.4
1.9
3.64
5.51
ug/l
0.83
38
470
7
61
1.15
0.17
1.3
1.1
—
—
—
0
0
786
7959
0.98
0.17
5.0
6.0
1.95
1.98
e9/l
0.63
719
7272
165
1592
1.04
0.17
1.6
1.9
—
—
—
0
0
38
349
1.09
0.17
1.2
1.2
—
—
—
0
0
181
1750
1.04
0.17
1.8
2.3
2.51
2.50
g/l
0.03
170
1645
15
129
1.16
0.17
1.1
1.1
—
—
—
0
0
10
120
0.83
0.16
3.9
3.3
484.70
684.03
u/ml
—
10
120
25
277
0.90
0.16
1.1
1.4
—
42.69
—
0
24
8
71
1.13
0.16
1.1
2.3
30.36
28.74
umol/l
—
8
66
11
92
1.20
0.16
1.2
1.9
—
—
—
0
0
14
121
1.16
0.15
1.4
2.2
53.50
65.57
%
1.08
14
121
51
479
1.07
0.14
1.5
1.3
—
—
—
0
0
162
1571
1.03
0.14
1.9
2.4
23.55
23.60
%
0.02
144
1380
48
510
0.94
0.13
1.3
1.3
2.57
10.06
u/ml
—
7
94
89
928
0.96
0.13
1.5
1.9
—
—
—
0
0
85
814
1.05
0.13
2.8
3.5
75.59
75.55
ng/l
0.00
79
738
49
462
1.06
0.13
1.1
1.1
2.56
1.19
u/ml
0.55
22
203
20
181
1.11
0.12
6.9
2.6
40.40
32.41
umol/l
0.70
20
174
18
162
1.11
0.12
1.1
1.2
—
—
—
0
0
20
219
0.91
0.11
1.1
1.8
—
47.36
—
0
14
45
475
0.95
0.11
1.4
2.1
—
—
—
0
0
89
922
0.96
0.10
1.5
1.6
—
—
—
0
0
10
115
0.87
0.10
2.4
1.4
1.05
1.00
promille
—
10
88
11
96
1.15
0.10
1.2
1.9
4.04
3.87
mmol/l
1.51
11
96
11
96
1.15
0.10
1.2
1.9
107.18
105.49
mmol/l
0.65
11
96
89
920
0.97
0.10
1.5
1.9
—
—
—
0
0
90
930
0.97
0.10
1.9
2.5
1.72
1.70
%
0.05
77
822
40
379
1.06
0.09
1.1
1.1
5.31
3.13
u/ml
0.44
15
137
36
340
1.06
0.09
1.1
1.4
—
—
—
0
0
89
917
0.97
0.08
1.5
1.9
—
—
—
0
0
17
185
0.92
0.08
1.4
1.6
—
—
—
0
0
6
71
0.84
0.07
1.2
3.5
—
—
—
0
0
39
372
1.05
0.07
2.3
3.9
24.09
24.20
mmol/l
0.08
39
364
58
601
0.96
0.07
2.0
2.4
—
—
—
0
0
8
77
1.04
0.07
1.0
1.1
—
—
—
0
0
33
347
0.95
0.07
1.1
1.0
0.12
0.45
u/ml
—
5
86
20
186
1.08
0.07
2.2
2.0
—
—
—
0
0
7
82
0.85
0.07
1.1
1.1
1850.00
1526.32
miu/ml
—
7
82
439
4351
1.01
0.07
4.8
6.2
1.07
1.06
inr
0.19
97
1441
10
89
1.12
0.07
2.4
3.0
9.24
113.61
mg/l
—
5
58
57
552
1.03
0.06
2.0
1.7
—
—
—
0
0
146
1435
1.02
0.06
3.5
3.4
4.52
4.51
pmol/l
0.06
130
1283
14
152
0.92
0.06
1.1
1.2
0.19
1.71
u/ml
—
9
87
81
830
0.97
0.06
1.5
1.9
—
—
—
0
0
18
168
1.07
0.06
1.3
1.4
—
—
—
0
0
18
192
0.94
0.05
1.1
1.4
—
—
—
0
0
30
287
1.05
0.05
1.8
1.7
1.18
1.38
g/l
0.59
25
243
113
1150
0.98
0.05
2.2
2.6
10.12
10.67
g/l
1.19
106
1066
710
7066
1.01
0.05
2.0
2.0
—
—
—
0
0
52
505
1.03
0.05
2.3
2.1
3.29
3.99
iu/l
0.47
21
241
33
343
0.96
0.04
1.5
1.3
—
—
—
0
0
871
8679
1.01
0.04
7.5
9.4
4.09
3.95
e9/l
0.94
771
7748
39
402
0.97
0.04
1.4
1.3
557.54
442.65
mg/l
0.37
39
385
39
402
0.97
0.04
1.2
1.1
—
—
—
0
0
33
319
1.04
0.03
3.4
3.4
0.22
0.29
g/l
0.41
13
131
180
1785
1.01
0.03
2.7
3.4
0.83
0.83
mmol/l
0.32
171
1709
24
232
1.03
0.02
1.6
1.7
5574.63
6283.44
e6/l
0.14
19
172
27
262
1.03
0.02
1.3
1.1
—
—
—
0
0
137
1359
1.01
0.02
1.3
1.3
110.75
232.40
u/ml
0.94
132
1256
206
2072
0.99
0.02
1.2
1.2
—
—
—
0
0
28
288
0.97
0.02
1.7
1.3
—
—
—
0
0
41
418
0.98
0.01
1.0
1.1
9.15
2.65
u/ml
0.47
14
178
16
153
1.05
0.01
1.2
1.2
—
—
—
0
0
41
403
1.02
0.01
1.0
1.2
—
—
—
0
0
13
136
0.96
0.00
5.8
7.3
—
—
—
0
0
29
296
0.98
0.00
2.3
2.4
—
—
—
0
0
43
424
1.01
0.00
1.1
1.1
—
—
—
0
0
10
95
1.05
0.00
2.3
2.8
45390.00
39101.05
ug/l
—
10
95
11
105
1.05
0.00
1.6
1.2
70.91
65.99
umol/l
0.20
11
105
43
425
1.01
0.00
1.1
1.1
—
—
—
0
0
54
539
1.00
0.00
1.5
2.0
21.57
20.52
s
0.57
42
444
159
1585
1.00
0.00
1.9
2.1
376.19
365.21
nmol/l
0.39
149
1462
38
376
1.01
0.00
1.9
2.4
—
—
—
0
0
47
474
0.99
0.00
1.2
1.1
—
—
—
0
0
53
532
1.00
0.00
1.3
1.3
—
—
—
0
0
35
352
0.99
0.00
1.5
1.4
17448.17
695.58
e6/l
0.46
29
286
39
388
1.01
0.00
1.1
1.1
1.44
2.54
u/ml
1.37
22
234
26
258
1.01
0.00
1.2
3.6
0.89
0.84
nmol/l
0.14
20
229
12
118
1.02
0.00
1.2
1.1
—
—
—
0
0
275
2752
1.00
0.00
1.4
1.4
—
—
—
0
0
13
127
1.02
0.00
1.1
1.0
280.69
309.60
mg/l
0.60
13
113
27
273
0.99
0.00
1.8
1.3
112.28
114.05
u/ml
—
10
62
35
353
0.99
0.00
1.4
1.4
26.93
20.74
e6/l
0.13
29
273
91
913
1.00
0.00
4.4
6.8
0.62
0.97
mmol/l
0.43
66
691
0
9
0.00
-0.00
0.0
1.0
—
—
—
0
0
1188
11880
1.00
-0.00
2.8
2.8
32.45
34.25
u/l
0.53
1158
11518
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
8
79
1.01
-0.00
2.3
1.7
—
—
—
0
0
21
210
1.00
-0.00
2.2
3.4
—
—
—
0
0
5
57
0.88
-0.00
1.0
1.8
18.20
17.74
umol/l
—
5
50
16
160
1.00
-0.00
2.0
1.4
0.89
0.95
g/l
0.60
16
160
6
61
0.98
-0.00
28.8
32.6
8.25
7.07
ug/l
—
6
56
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
222.62
—
0
5
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
2.1
—
—
—
0
0
0
9
0.00
-0.00
0.0
2.6
—
40.33
—
0
9
0
5
0.00
-0.00
0.0
1.0
—
76.80
—
0
5
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.6
—
40.43
—
0
7
0
6
0.00
-0.00
0.0
1.3
—
230.83
—
0
6
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.3
—
2.88
—
0
7
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
4.6
—
490.20
—
0
5

Mortality – FinRegistry

Association

Association between endpoint O15_MATERN_CARE_DISPROP and mortality.

Females

Parameter HR [95% CI] p-value
O15_MATERN_CARE_DISPROP 0.535 [0.43, 0.67] < 0.001
Birth year 0.993 [0.98, 1.0] 0.104

During the follow-up period (1.1.1998 — 31.12.2019), 89 out of 11794 females with O15_MATERN_CARE_DISPROP died.

Males

No data

Mortality risk

Mortality risk for people of age

years, who have O15_MATERN_CARE_DISPROP.

N-year risk Females Males
1 0.059% No data
5 0.321% No data
10 0.697% No data
15 1.412% No data
20 2.428% No data

Relationships between endpoints

Index endpoint: O15_MATERN_CARE_DISPROP – Maternal care for known or suspected disproportion

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
loading spinner Loading data