esophageal disease: A non-neoplastic or neoplastic disorder that affects the esophagus. Representative examples of non-neoplastic disorders include esophagitis and esophageal ulcer. Representative examples of neoplastic disorders include carcinomas, lymphomas, and melanomas.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleNone |
520210 |
2. Check conditionsNone |
520210 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
172 |
4. Check minimum number of eventsNone |
172 |
5. Include endpointsNone |
172 |
6. Filter based on genotype QC (FinnGen only) |
172 |
Control definitions (FinnGen only)
- Control exclude
- K11_OESSTODUO
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- K22
- Name in latin
- Perforatio oesophagi
Similar endpoints
↥List of similar endpoints to
Perforation of oesophagus
based on the number of shared cases.
Similar with more cases:
- Diseases of oesophagus, stomach and duodenum
- Gastrointestinal diseases
- Any operation in hilmo
- Any event in hilmo or specialist outpatient
- Any prescribed medicine buy
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 1531 | 568 | 942 |
| Only index persons | 1177 | 448 | 729 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.02 | 0.02 | 0.03 |
| Only index persons | 0.02 | 0.02 | 0.03 |
| Median age at first event (years) | |||
| Whole population | 65.20 | 69.78 | 62.30 |
| Only index persons | 64.77 | 68.22 | 62.65 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 172 | 65 | 107 |
| Unadjusted period prevalence (%) | 0.04 | 0.02 | 0.05 |
| Median age at first event (years) | 63.00 | 61.45 | 63.94 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
No data
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 154
- Matched controls
- 1540
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
K22.3
ICD-10 Finland
Perforation of oesophagus
+∞
206.4
148
*
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
28.4
70.3
119
164
JCF12
NOMESCO Finland
Endoscopic insertion of prosthetic tube into oesphagus
399.8
56.1
53
*
K22.2
ICD-10 Finland
Oesophageal obstruction
+∞
43.9
40
*
504
Kela drug reimbursment
Conditions requiring daily forced enteral nutrition
60.6
41.0
47
11
JC2AB
NOMESCO Finland
Oesophagus X-ray examination with contrast
129.5
37.7
39
*
JCA55
NOMESCO Finland
Endoscopic dilatation of oesophagus
454.5
36.6
35
*
JDW98
NOMESCO Finland
Other transluminal endoscopic operation on stomach or duodenum
59.2
34.8
40
9
UJC12
NOMESCO Finland
Flexible oesophagoscopy
200.2
32.0
32
*
R13
ICD-10 Finland
Dysphagia
13.5
25.4
46
47
JDB10
NOMESCO Finland
Percutaneous gastrostomy
50.4
24.6
29
7
UJD02
NOMESCO Finland
Gastroscopy
25.5
22.3
31
15
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
11.6
20.8
40
45
JCA08
NOMESCO Finland
Endoscopic removal of foreign body from oesophagus
+∞
20.2
19
*
A02BC05
ATC
esomeprazole; systemic
4.7
18.3
92
369
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
5.4
18.1
65
182
JCE00
NOMESCO Finland
Suture of oesophagus
202.3
17.9
18
*
JAH00
NOMESCO Finland
Laparotomy
25.5
17.5
24
11
GD1BD
NOMESCO Finland
Thorax extensive CT-examination
11.6
17.0
32
34
TJD20
NOMESCO Finland
Change of gastrostomy tube
45.5
16.8
20
5
R4190
NOMESCO Finland
Nutritional therapy
16.2
16.2
26
19
JCB00
NOMESCO Finland
Oesophagostomy
+∞
15.9
15
*
GD1AA
NOMESCO Finland
Thorax X-ray examination
4.1
15.6
101
485
T18.1
ICD-10 Finland
Foreign body in oesophagus
88.8
14.9
16
*
K22.1
ICD-10 Finland
Ulcer of oesophagus
165.0
14.7
15
*
K21.0
ICD-10 Finland
Gastro-oesophageal reflux disease with oesophagitis
25.3
14.6
20
9
UJC02
NOMESCO Finland
Rigid oesophagoscopy
82.3
13.8
15
*
WX408
NOMESCO Finland
General anesthesy, balanced
4.0
13.8
70
263
JN3AA
NOMESCO Finland
Abdominal X-ray examination without contrast
9.8
13.8
28
34
K22.0
ICD-10 Finland
Achalasia of cardia
+∞
13.7
13
*
JDB00
NOMESCO Finland
Gastrostomy
+∞
13.7
13
*
JCC10
NOMESCO Finland
Transthoracic partial oesophagectomy without interposition
+∞
12.7
12
*
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
4.6
12.5
49
143
WX402
NOMESCO Finland
General anaesthesia
4.6
11.9
46
131
WX872
NOMESCO Finland
Intensive care
7.2
11.8
29
48
K20
ICD-10 Finland
Oesophagitis
129.3
11.6
12
*
C15.5
ICD-10 Finland
Malignant neoplasm: Lower third of oesophagus
47.0
11.1
13
*
WX302
NOMESCO Finland
Thoracal epidural anesthesy
9.1
11.1
23
29
WX602
NOMESCO Finland
Repeated or continuing anesthesia shots throug a catheter
7.4
10.9
26
41
WX404
NOMESCO Finland
Intravenous generell anesthesy
3.8
10.8
53
187
WX892
NOMESCO Finland
Monitored bed care
6.6
10.8
28
50
UGC12
NOMESCO Finland
Flexible bronchoscopy
5.5
10.7
33
73
TPH20
NOMESCO Finland
Insertion of central venous catheter through subclavian or brachiocephalic vein
8.5
10.7
23
31
C15.9
ICD-10 Finland
Malignant neoplasm: Oesophagus, unspecified
117.7
10.6
11
*
TPH30
NOMESCO Finland
Insertion of central venous catheter through periferal vein
35.2
10.5
13
*
A02BC02
ATC
pantoprazole; systemic
3.3
10.5
112
693
GD1AD
NOMESCO Finland
Thorax CT examination
9.5
10.5
21
25
GD5BD
NOMESCO Finland
Thorax and upper abdomen combined extensive CT examination of
12.6
10.4
18
16
JN4BD
NOMESCO Finland
Extensive body CT
4.6
10.4
38
102
A03FA01
ATC
metoclopramide; systemic, rectal
3.8
10.3
50
174
WX002
NOMESCO Finland
Sedation and analgesia
3.9
10.2
46
150
RD210
NOMESCO Finland
NA
28.2
10.0
13
5
GD1CD
NOMESCO Finland
Thorax extensive CT-examination
23.5
9.5
13
6
K22.4
ICD-10 Finland
Dyskinesia of oesophagus
+∞
9.5
9
*
TJF00
NOMESCO Finland
Insertion of jejunal tube
+∞
9.5
9
*
JCE96
NOMESCO Finland
Other reconstruction of oesophagus
+∞
9.5
9
*
K22.9
ICD-10 Finland
Disease of oesophagus, unspecified
+∞
9.5
9
*
Y83
ICD-10 Finland
Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
5.6
9.3
27
56
N05CF01
ATC
zopiclone; oral
3.1
9.0
64
290
R4110
NOMESCO Finland
Physiotherapy
3.1
8.8
57
242
J01MA12
ATC
levofloxacin; systemic
3.6
8.8
44
155
JC2KB
NOMESCO Finland
Functional X-ray examination of swallowing
53.1
8.8
10
*
T81.8
ICD-10 Finland
Other complications of procedures, not elsewhere classified
17.6
8.7
13
8
GA4AT
NOMESCO Finland
Cathetrisation of pleural cavity with ultrasound guidance
21.5
8.6
12
6
TPH04
NOMESCO Finland
Cathetrisation of vein
3.2
8.5
50
199
JCD03
NOMESCO Finland
Subcutaneous anastomosis of oesophagus with interposition of intestine
+∞
8.4
8
*
K22.8
ICD-10 Finland
Other specified diseases of oesophagus
+∞
8.4
8
*
5304A
ICD-9 Finland
Diseases of oesophagus, Perforation of oesophagus
+∞
8.4
8
*
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
2.9
8.3
63
295
K44.9
ICD-10 Finland
Diaphragmatic hernia without obstruction or gangrene
8.0
8.2
18
25
Z98.8
ICD-10 Finland
Other specified postsurgical states
18.4
8.2
12
7
GAB10
NOMESCO Finland
Antero- or postero-lateral thoracotomy
35.4
8.2
10
*
GAA10
NOMESCO Finland
Intercostal insertion of pleural drainage tube
12.8
7.7
13
11
J18.9
ICD-10 Finland
Pneumonia, unspecified
2.8
7.6
58
270
TPH07
NOMESCO Finland
Cathetrisation of artery
4.0
7.5
31
92
K92.0
ICD-10 Finland
Haematemesis
14.3
7.5
12
9
J01MA14
ATC
moxifloxacin; systemic
4.2
7.4
28
77
JCC96
NOMESCO Finland
Other partial oesophagectomy
+∞
7.3
7
*
JCF00
NOMESCO Finland
Insertion of prosthetic tube into oesphagus
+∞
7.3
7
*
T36
ICD-10 Finland
Poisoning by systemic antibiotics
12.9
7.2
12
10
F10.1
ICD-10 Finland
Mental and behavioural disorders due to use of alcohol, Harmful use
6.4
7.2
18
31
A02BC03
ATC
lansoprazole; oral
2.7
7.0
55
260
JDB01
NOMESCO Finland
Laparoscopic gastrostomy
42.0
6.8
8
*
Z43.1
ICD-10 Finland
Attention to gastrostomy
42.0
6.8
8
*
GBB00
NOMESCO Finland
Tracheostomy
15.2
6.5
10
7
WX000
NOMESCO Finland
Monitoring vital functions without anesthesy
7.6
6.4
14
20
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
3.4
6.4
31
106
N03AX16
ATC
pregabalin; oral
2.7
6.3
47
213
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
3.9
6.3
25
72
K22.6
ICD-10 Finland
Gastro-oesophageal laceration-haemorrhage syndrome
+∞
6.3
6
*
JDA55
NOMESCO Finland
Endoscopic dilatation of stomach, pylorus or anastomosis of stomach
+∞
6.3
6
*
J98.5
ICD-10 Finland
Diseases of mediastinum, not elsewhere classified
+∞
6.3
6
*
A28
ICPC
Limited function/disability NOS
3.2
6.1
33
121
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
48
115
5.40
19.91
5.8
6.6
8.1
9.7
mmol/l
0.93
48
108
39
100
4.75
14.65
1.9
1.6
—
—
—
0
0
72
313
3.24
12.38
5.7
2.5
—
—
—
0
0
56
217
3.34
11.54
2.2
1.9
—
—
—
0
0
39
126
3.71
10.57
3.5
2.2
0.2
0.2
g/l
1.97
39
117
110
690
2.65
8.58
11.6
6.4
1.2
1.2
mmol/l
0.81
97
575
40
153
3.10
8.18
1.8
1.9
—
—
—
0
0
100
614
2.50
7.94
9.3
4.0
—
—
—
0
0
39
150
3.07
7.88
1.8
1.8
—
—
—
0
0
101
632
2.45
7.57
9.9
5.8
1.2
1.2
mmol/l
1.66
96
572
41
167
2.91
7.47
13.1
6.2
12.9
11.4
kpa
1.04
41
158
41
167
2.91
7.47
13.1
6.3
5.5
5.1
kpa
1.48
41
158
55
266
2.57
7.16
4.1
3.3
95.7
232.0
ng/l
0.78
45
218
63
337
2.37
6.51
2.8
1.9
3.0
3.2
mg/l
0.19
53
290
11
19
6.12
6.19
1.4
1.5
—
—
—
0
0
11
19
6.12
6.19
1.4
1.5
—
—
—
0
0
11
20
5.81
5.88
1.4
1.5
—
—
—
0
0
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
16
41
4.20
5.86
3.3
2.1
0.2
0.4
u/ml
—
8
19
30
117
2.89
5.84
1.8
2.0
382.7
362.8
nmol/l
0.14
25
105
83
525
2.12
5.51
2.5
1.9
85.2
95.3
pmol/l
1.46
50
284
69
422
2.06
4.87
4.9
3.4
35.1
33.3
u/l
0.15
69
402
21
74
3.09
4.86
16.8
8.1
26.3
24.5
mmol/l
1.31
21
69
48
256
2.21
4.82
1.8
1.7
2.1
1.3
mg/l
0.47
38
203
65
394
2.04
4.67
3.6
3.1
0.3
0.4
e6/l
0.62
55
306
105
757
1.99
4.57
14.8
9.9
4.9
4.1
e9/l
2.15
93
674
21
79
2.89
4.34
1.9
1.7
—
—
—
0
0
77
508
1.93
4.26
3.6
3.2
—
—
—
0
0
21
83
2.74
3.97
7.3
6.0
26.6
24.2
mmol/l
2.45
21
83
69
450
1.89
3.88
3.5
3.3
2.3
2.3
mmol/l
1.10
62
399
45
254
2.05
3.83
2.7
1.7
1103.0
1283.9
nmol/l
0.66
38
191
43
239
2.07
3.82
2.4
2.2
29.3
29.5
s
0.11
43
228
12
36
3.51
3.55
1.5
1.2
—
—
—
0
0
76
525
1.80
3.47
3.5
2.5
139.3
177.3
ug/l
0.74
71
471
7
11
6.58
3.21
3.3
2.4
—
—
—
0
0
28
143
2.14
3.07
3.4
5.3
3.8
34.5
ug/l
0.56
23
125
33
182
2.01
2.96
19.1
26.0
1.2
1.2
inr
—
10
17
6
9
6.86
2.89
1.0
1.1
—
—
—
0
0
5
6
8.53
2.76
1.4
1.0
—
—
—
0
0
7
14
5.16
2.75
1.0
1.4
444.6
236.4
u/l
—
7
14
20
93
2.30
2.73
10.3
6.9
24.9
24.3
mmol/l
0.36
20
86
13
49
2.79
2.69
2.5
1.8
—
—
—
0
0
10
33
3.16
2.57
2.1
1.5
—
—
—
0
0
13
51
2.68
2.51
3.2
2.1
—
—
—
0
0
24
127
2.03
2.41
2.0
3.6
61.6
66.1
g/l
1.64
24
114
11
41
2.80
2.32
1.5
1.2
—
—
—
0
0
40
254
1.75
2.32
4.1
3.1
2.5
2.4
mmol/l
0.86
34
232
36
224
1.77
2.23
3.1
2.9
1.4
1.6
e6/l
0.09
20
129
120
1356
0.62
2.08
4.6
4.5
1.5
1.4
mmol/l
0.25
107
1222
20
105
2.02
2.06
3.0
2.4
84.4
62.1
ml/min/173m2
—
5
40
12
51
2.45
2.00
2.3
2.4
—
—
—
0
0
75
577
1.53
1.98
4.0
3.8
23.7
53.0
ng/l
2.26
61
430
125
1393
0.62
1.92
5.2
5.2
2.5
2.6
mmol/l
0.96
115
1259
6
17
3.62
1.85
3.8
4.9
—
—
—
0
0
112
947
1.52
1.85
3.2
3.6
15.0
15.0
pmol/l
0.00
104
839
36
237
1.66
1.82
3.2
2.7
1.3
0.9
e6/l
0.21
20
140
123
1363
0.66
1.62
4.7
4.6
4.4
4.5
mmol/l
0.81
113
1239
8
32
2.57
1.62
1.8
1.7
—
—
—
0
0
8
32
2.57
1.62
1.5
1.7
—
—
—
0
0
17
93
1.92
1.58
1.9
1.4
—
—
—
0
0
10
44
2.35
1.56
1.6
1.6
—
—
—
0
0
6
21
2.92
1.52
2.0
1.8
—
—
—
0
0
6
22
2.79
1.44
2.0
1.8
—
—
—
0
0
6
22
2.79
1.44
2.0
1.8
—
—
—
0
0
24
155
1.64
1.32
5.0
3.3
—
—
—
0
0
5
18
2.83
1.29
1.0
1.2
—
—
—
0
0
118
1295
0.72
1.17
5.9
6.0
39.3
40.4
mmol/mol
0.88
113
1196
5
20
2.54
1.16
2.2
1.8
—
—
—
0
0
7
30
2.39
1.13
1.0
1.1
23.9
26.7
u/l
—
7
25
87
744
1.34
1.11
2.6
2.7
—
—
—
0
0
5
21
2.42
1.10
1.2
1.3
—
—
—
0
0
5
21
2.42
1.10
2.2
1.8
—
—
—
0
0
5
21
2.42
1.10
2.2
1.8
—
—
—
0
0
11
60
1.89
1.05
1.1
2.6
—
—
—
0
0
10
54
1.90
0.99
1.1
2.7
8.2
10.6
g/l
—
10
47
9
51
1.81
0.96
1.1
2.8
36.8
37.6
g/l
—
9
43
145
1365
1.40
0.82
41.8
14.3
37.7
23.4
mg/l
4.68
140
1079
6
32
1.91
0.82
1.2
1.7
291.0
323.6
mu/l
—
6
32
11
174
0.61
0.82
1.4
1.3
19.7
20.0
u/ml
—
6
77
7
38
1.88
0.74
1.1
1.8
—
—
—
0
0
5
94
0.52
0.69
1.2
1.7
—
—
—
0
0
7
43
1.65
0.67
1.9
1.7
—
—
—
0
0
8
127
0.61
0.67
1.1
1.4
—
—
—
0
0
128
1197
1.27
0.66
40.4
14.9
36.7
40.3
%
3.62
87
835
123
1307
0.79
0.65
4.5
4.1
1.2
1.3
mmol/l
1.46
110
1176
5
29
1.75
0.64
1.4
1.2
569.6
459.3
mg/l
—
5
29
57
651
0.81
0.59
5.1
5.1
2.0
2.6
ug/l
0.50
49
583
23
178
1.34
0.56
3.3
5.1
216.0
233.9
u/l
0.83
23
167
45
519
0.82
0.50
3.5
4.6
19.3
21.5
%
0.46
23
265
32
380
0.81
0.47
3.0
3.1
0.6
0.7
ug/l
0.76
27
255
5
81
0.61
0.47
1.0
2.0
—
—
—
0
0
39
449
0.83
0.43
3.5
4.1
12.5
10.0
mg/mmol
0.09
27
288
5
32
1.58
0.42
1.2
1.8
—
—
—
0
0
0
15
0.00
0.41
0.0
4.1
—
—
—
0
0
12
88
1.39
0.41
3.1
3.6
102.5
82.1
ng/l
0.32
12
78
0
17
0.00
0.41
0.0
1.7
—
—
—
0
0
126
1206
1.17
0.36
4.5
4.3
1.9
2.0
mu/l
0.84
117
1074
73
674
1.14
0.34
3.6
3.5
0.0
0.0
estimate
0.00
19
129
6
86
0.69
0.34
1.2
2.2
—
—
—
0
0
72
668
1.13
0.31
5.0
4.6
0.0
0.0
estimate
0.00
19
135
71
664
1.12
0.26
3.7
3.5
0.0
0.0
estimate
0.00
19
137
0
11
0.00
0.21
0.0
1.5
—
4.2
—
0
5
0
10
0.00
0.21
0.0
1.0
—
548.8
—
0
5
0
10
0.00
0.21
0.0
2.2
—
13.6
—
0
10
0
10
0.00
0.21
0.0
1.2
—
11.6
—
0
10
0
10
0.00
0.21
0.0
1.0
—
35.1
—
0
5
0
12
0.00
0.21
0.0
1.8
—
—
—
0
0
0
12
0.00
0.21
0.0
1.2
—
—
—
0
0
0
12
0.00
0.21
0.0
2.9
—
—
—
0
0
0
12
0.00
0.21
0.0
1.2
—
—
—
0
0
0
13
0.00
0.21
0.0
1.2
—
—
—
0
0
129
1323
0.90
0.20
5.0
4.7
5.9
6.1
mmol/l
1.03
123
1194
37
391
0.93
0.10
4.0
3.7
0.0
0.0
estimate
0.00
19
128
5
44
1.14
0.10
1.0
1.2
—
—
—
0
0
5
44
1.14
0.10
1.0
1.2
—
—
—
0
0
128
1300
0.94
0.09
34.1
14.1
84.2
78.6
ml/min/173m2
1.72
118
1065
6
53
1.14
0.09
1.0
2.1
29.6
35.8
u/l
—
6
44
16
175
0.91
0.09
1.4
1.5
—
—
—
0
0
51
530
0.95
0.09
4.1
3.7
—
—
—
0
0
7
63
1.12
0.08
1.3
1.0
—
—
—
0
0
37
379
0.97
0.02
3.1
3.0
12293.5
2842.5
umol/l
0.36
32
328
18
179
1.01
0.00
9.7
8.3
—
—
—
0
0
0
6
0.00
0.00
0.0
4.2
—
—
—
0
0
6
66
0.91
0.00
1.2
1.3
—
—
—
0
0
0
6
0.00
0.00
0.0
1.8
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
0.00
0.0
1.8
—
—
—
0
0
0
7
0.00
0.00
0.0
1.4
—
—
—
0
0
0
6
0.00
0.00
0.0
1.8
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
4.2
—
—
—
0
0
0
6
0.00
0.00
0.0
1.8
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
0
8
0.00
0.00
0.0
2.0
—
—
—
0
0
0
9
0.00
0.00
0.0
1.3
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint K11_PERFOES and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| K11_PERFOES | 2.851 [2.1, 3.87] | < 0.001 |
| Birth year | 0.993 [0.98, 1.0] | 0.097 |
During the follow-up period (1.1.1998 — 31.12.2019), 161 out of 359 females with K11_PERFOES died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| K11_PERFOES | 3.71 [2.7, 5.09] | < 0.001 |
| Birth year | 0.992 [0.98, 1.0] | 0.097 |
During the follow-up period (1.1.1998 — 31.12.2019), 293 out of 605 males with K11_PERFOES died.
Mortality risk
Mortality risk for people of age
years, who have K11_PERFOES.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.263% | 0.671% |
| 5 | 1.521% | 4.559% |
| 10 | 3.626% | 11.643% |
| 15 | 7.001% | 21.535% |
| 20 | 12.095% | 35.304% |
Relationships between endpoints
↥Index endpoint: K11_PERFOES – Perforation of oesophagus
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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