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This is a non-core endpoint: only basic statistics are computed.

Macular hole, drug-induced

Endpoint Browser

MACULAR_HOLE_ADVERSE

Endpoint definition

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Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ATC codes for adverse effects of Drugs — ANY
  • Hospital discharge: ICD-10 — H35.37#

1 out of 7 registries used, show all original rules.

6

4. Check minimum number of events

None

6

5. Include endpoints

None

6

6. Filter based on genotype QC (FinnGen only)

6

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy
C
First used in FinnGen datafreeze
DF5
Parent code in ICD-10
H35

Case counts by codes

↥

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

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-FinRegistry-

This endpoint is excluded (not available in FinRegistry).

-FinnGen-

Key figures

All Female Male
Number of individuals 6 - -
Unadjusted period prevalence (%) 0.00 - -
Median age at first event (years) 67.79 - -

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS (R11)

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CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

No data available

LabWAS

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OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
6
36
+∞
1.10
5.0
3.9
—
—
—
0
0
0
10
0.00
0.24
0.0
1.0
—
—
—
0
0
0
12
0.00
0.23
0.0
1.5
—
14.6
—
0
12
0
12
0.00
0.23
0.0
1.5
—
2.5
—
0
12
0
13
0.00
0.23
0.0
3.5
—
—
—
0
0
0
13
0.00
0.23
0.0
5.8
—
—
—
0
0
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
0.00
0.0
1.5
—
—
—
0
0
6
54
+∞
0.00
13.7
22.7
90.2
91.8
fl
—
6
54
6
54
+∞
0.00
12.3
19.1
78.2
83.2
umol/l
—
6
54
6
54
+∞
0.00
13.7
22.9
133.8
136.4
g/l
—
6
54
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
0.00
0.0
3.7
—
—
—
0
0
0
6
0.00
0.00
0.0
1.3
—
—
—
0
0
6
54
+∞
0.00
13.7
22.8
29.7
30.4
pg
—
6
54
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
6
53
+∞
0.00
9.5
14.2
—
—
—
0
0
6
53
+∞
0.00
11.5
19.6
140.2
140.5
mmol/l
—
6
53
0
5
0.00
0.00
0.0
1.6
—
7.8
—
0
5
0
7
0.00
0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
0.00
0.0
18.4
—
104.4
—
0
5
0
8
0.00
0.00
0.0
1.1
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
2.2
—
7.4
—
0
5
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
6
53
+∞
0.00
11.7
20.0
3.9
4.0
mmol/l
—
6
53
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.6
—
4.8
—
0
5
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0

Mortality – FinRegistry

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This endpoint is excluded (not available in FinRegistry).

Relationships between endpoints

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Index endpoint: MACULAR_HOLE_ADVERSE – Macular hole, drug-induced

GWS hits: -

This endpoint is excluded (not available in FinRegistry).