vitamin B12 deficiency: A disease characterized by low serum levels of vitamin B12, either inherited or acquired.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleNone |
520210 |
2. Check conditionsNone |
520210 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
3 out of 7 registries used, show all original rules. |
4568 |
4. Check minimum number of eventsNone |
4568 |
5. Include endpointsNone |
4568 |
6. Filter based on genotype QC (FinnGen only) |
4568 |
Control definitions (FinnGen only)
- Control exclude
- D3_NUTRIANAEMIA
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- D50-D53
- Name in latin
- Anaemia ex deficientia vitamini B12
Similar endpoints
↥List of similar endpoints to
Vitamin B12 deficiency anaemia
based on the number of shared cases.
Similar with more cases:
- Nutritional anaemias
- Anaemias
- Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
- Autoimmune diseases
- Used for control exclusion in common control thyroid runs
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 52228 | 29010 | 22438 |
| Only index persons | 35116 | 20477 | 14639 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.74 | 0.83 | 0.63 |
| Only index persons | 0.67 | 0.75 | 0.56 |
| Median age at first event (years) | |||
| Whole population | 69.57 | 69.67 | 69.40 |
| Only index persons | 67.32 | 66.96 | 67.81 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 4568 | 2308 | 2260 |
| Unadjusted period prevalence (%) | 0.89 | 0.79 | 1.00 |
| Median age at first event (years) | 62.07 | 57.97 | 66.27 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 4136
- Matched controls
- 41350
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
D50.9
ICD-10 Finland
Iron deficiency anaemia, unspecified
23.3
323.0
662
336
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
5.2
323.0
2180
7299
D51.9
ICD-10 Finland
Vitamin B12deficiency anaemia, unspecified
217.9
323.0
1116
70
B81
ICPC
Anaemia vit B12/folate deficiency
81.4
323.0
2133
533
B03BA03
ATC
hydroxocobalamin; parenteral
248.3
323.0
3549
981
D51.0
ICD-10 Finland
Vitamin B12deficiency anaemia due to intrinsic factor deficiency
654.1
323.0
754
14
B03BA02
ATC
cyanocobalamin tannin complex; parenteral
76.6
323.0
377
54
107
Kela drug reimbursment
Pernicious anaemia
+∞
323.0
3049
*
K29.4
ICD-10 Finland
Chronic atrophic gastritis
41.3
323.0
1028
328
601
Kela drug reimbursment
Severe malabsorption of nutrients, mainly fats
41.7
268.0
338
88
JDD00
NOMESCO Finland
Total gastrectomy and Roux-en-Y oesophagojejunostomy
210.6
249.6
257
13
T91
ICPC
Vitamin/nutritional deficiency
36.4
204.8
266
78
D64.9
ICD-10 Finland
Anaemia, unspecified
4.3
193.2
827
2294
SPAT1256
SPAT
Intramuscular and subcutaneous injection
2.7
193.1
2143
11822
D51
ICD-10 Finland
Vitamin B12deficiency anaemia
54.2
188.6
226
44
-50
ICPC
Medication/prescr/renewal
6.7
177.8
484
798
D51.8
ICD-10 Finland
Other vitamin B12deficiency anaemias
198.0
165.2
171
9
C16.9
ICD-10 Finland
Malignant neoplasm: Stomach, unspecified
28.5
142.3
196
72
B03BA01
ATC
cyanocobalamin; nasal, systemic
1355.0
135.1
131
*
E53.8
ICD-10 Finland
Deficiency of other specified B group vitamins
25.4
120.4
171
70
H03AA01
ATC
levothyroxine sodium; systemic
2.4
113.3
1207
6024
D50.0
ICD-10 Finland
Iron deficiency anaemia secondary to blood loss (chronic)
19.0
106.1
165
90
104
Kela drug reimbursment
Thyroid insufficiency
3.6
105.6
530
1624
A50
ICPC
General and Unspecified, Medication/prescr/renewal
5.8
103.5
310
567
B50
ICPC
Blood and Immunity, Medication/prescr/renewal
70.6
102.0
117
17
A55
ICPC
General and Unspecified, Local injection/infiltration
17.3
100.7
162
97
UJF32
NOMESCO Finland
Coloscopy
2.2
98.5
1264
6816
K50.0
ICD-10 Finland
Crohn disease of small intestine
14.6
96.4
166
118
D13.1
ICD-10 Finland
Benign neoplasm: Stomach
7.5
88.3
217
302
WVA30
SPAT
NA
6.8
88.1
233
361
K50.8
ICD-10 Finland
Other Crohn disease
12.8
86.7
158
128
E03.9
ICD-10 Finland
Hypothyroidism, unspecified
2.7
85.2
667
2753
8140/3-C16.9
ICD-O-3
Adenocarcinoma, NOS, of stomach, NOS
35.3
84.6
110
32
376
Kela drug reimbursment
Cyanocobalamin
824.4
82.8
81
*
SPAT1254
SPAT
Administration of medicine
2.4
79.6
815
3882
2810X
ICD-9 Finland
Other deficiency anaemias, Pernicious anaemia[ANAEMIA PERNICIOSA SINE MYELOPATHIA SPINALI]
+∞
78.4
75
*
8145/3-C16.9
ICD-O-3
Carcinoma, diffuse type of stomach, NOS
62.0
77.9
91
15
D50.8
ICD-10 Finland
Other iron deficiency anaemias
18.4
72.1
113
63
B82
ICPC
Anaemia other/unspecified
6.2
71.4
201
338
UJF30
NOMESCO Finland
Ileoscopy through colon
2.9
66.2
447
1666
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
1.8
65.5
1536
10108
K50.9
ICD-10 Finland
Crohn disease, unspecified
9.4
64.6
137
150
UJD02
NOMESCO Finland
Gastroscopy
3.5
63.7
326
1000
C16.23
ICD-10 Finland
Malignant tumor of the corpus ventriculi diffuse carcinoma
73.4
63.3
72
10
L04AX01
ATC
azathioprine; systemic
4.3
59.6
236
580
208
Kela drug reimbursment
Ulcerative colitis and Crohn's disease
4.3
59.3
233
568
A07EA06
ATC
budesonide; oral, local oral
4.9
59.0
202
428
C16.00
ICD-10 Finland
Cardia
22.6
56.3
82
37
K50.1
ICD-10 Finland
Crohn disease of large intestine
10.2
55.3
112
113
C16.20
ICD-10 Finland
Malignant tumor of the corpus ventriculi without histology
50.7
54.1
65
13
C10AC01
ATC
colestyramine; oral
4.6
52.0
190
431
B80
ICPC
Iron deficiency anaemia
6.8
51.3
134
204
6322
FHL
Gastrectomy (including Roux-Y)
503.8
50.5
50
*
C16.29
ICD-10 Finland
Malignant tumor of the corpus ventriculi other or unspecified carcinoma
58.8
49.5
58
10
-55
ICPC
Local injection/infiltration
9.7
49.1
102
108
D37.1
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Stomach
10.2
48.7
98
98
S50
ICPC
Skin, Medication/prescr/renewal
9.6
48.4
101
108
C16.39
ICD-10 Finland
Malignant tumor of the antrum ventriculi other or unspecified carcinoma
40.6
47.9
60
15
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.7
47.0
1334
9071
130
Kela drug reimbursment
Malignant tumour
2.4
47.0
451
2036
C16.2
ICD-10 Finland
Malignant neoplasm: Body of stomach
32.6
46.4
61
19
TPH04
NOMESCO Finland
Cathetrisation of vein
1.8
46.2
885
5314
A10AB05
ATC
insulin aspart; parenteral (insulins and analog. for injection, fast-acting)
2.6
45.6
364
1490
ZX120
NOMESCO Finland
Intravenous
2.3
45.1
441
2006
UJF92
NOMESCO Finland
Capsular endoscopy
8.6
44.8
99
117
A10AE04
ATC
insulin glargine; parenteral
2.3
42.8
439
2044
JDA05
NOMESCO Finland
Endoscopic polypectomy in stomach or pylorus
19.7
42.2
64
33
C16.30
ICD-10 Finland
Malignant tumor of the antrum ventriculi without histology
36.4
42.2
54
15
C16.33
ICD-10 Finland
Malignant tumor of the antrum ventriculi diffuse carcinoma
93.0
41.8
46
5
JFB00
NOMESCO Finland
Partial resection of small intestine
5.5
41.1
125
232
Z71.3
ICD-10 Finland
Dietary counselling and surveillance
3.3
40.4
215
677
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
2.0
40.2
558
2959
C16.24
ICD-10 Finland
Malignant tumor of the corpus ventriculi intestinal carcinoma
52.8
39.5
47
9
8240/3-C16.9
ICD-O-3
Neuroendocrine tumor, NOS, of stomach, NOS
138.0
38.8
41
*
JKA20
NOMESCO Finland
Cholecystectomy
3.4
37.9
189
566
E10.9
ICD-10 Finland
Type 1 diabetes mellitus, Without complications
3.6
37.9
177
503
A07EC02
ATC
mesalazine; oral, rectal
3.0
37.9
238
838
A03FA01
ATC
metoclopramide; systemic, rectal
1.7
37.9
851
5337
JF1CG
NOMESCO Finland
Extensive MRI of small bowel
18.4
37.5
58
32
C16.09
ICD-10 Finland
Malignant tumor of cardiac or other unspecified carcinoma
18.6
37.0
57
31
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.5
36.3
1739
13281
A09AA02
ATC
multienzymes (lipase, protease etc.)
4.4
35.7
135
318
C16
ICD-10 Finland
Malignant neoplasm of stomach
181.5
34.8
36
*
B81
ICD-10 Finland
Other intestinal helminthiases, not elsewhere classified
124.4
34.7
37
*
D50
ICPC
Digestive, Medication/prescr/renewal
39.5
34.3
43
11
T89
ICPC
Diabetes insulin dependent
3.6
34.1
158
446
D53.1
ICD-10 Finland
Other megaloblastic anaemias, not elsewhere classified
31.7
33.5
44
14
S55
ICPC
Skin, Local injection/infiltration
23.7
33.1
47
20
133
Kela drug reimbursment
Severe chronic pancreatic insufficiency
5.4
32.7
100
188
56300
ICD-8 Finland
Chronic enteritis and ulcerative colitis, Regional enteritis
24.4
32.7
46
19
WX408
NOMESCO Finland
General anesthesy, balanced
1.6
32.6
971
6557
C16.8
ICD-10 Finland
Malignant neoplasm: Overlapping lesion of stomach
22.6
32.6
47
21
5552A
ICD-9 Finland
Regional enteritis, Small intestine with large intestine
49.2
32.5
39
8
L01BC06
ATC
capecitabine; oral
3.1
32.5
187
623
28110
ICD-8 Finland
Other vitamin B12 deficiency anaemia, Other vitamin B12 deficiency
+∞
32.3
31
*
C16.34
ICD-10 Finland
Malignant tumor of the antrum ventriculi intestinal carcinoma
62.2
32.0
37
6
JN3BD
NOMESCO Finland
Extensive abdominal CT
2.0
31.6
444
2355
E03.80
ICD-10 Finland
Hypothyroidism caused by autoimmune thyroiditis
5.1
31.3
101
202
K56.6
ICD-10 Finland
Other and unspecified intestinal obstruction
3.0
31.2
187
641
A02BC02
ATC
pantoprazole; systemic
1.5
31.2
2450
20538
JN4BD
NOMESCO Finland
Extensive body CT
1.9
30.6
462
2516
28109
ICD-8 Finland
Other vitamin B12 deficiency anaemia, Perniciosa non definita
+∞
30.2
29
*
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
1.8
30.1
613
3697
A10AC01
ATC
insulin (human); parenteral (insulins and analog. for injection, intermediate-acting)
2.1
29.9
372
1879
D51.1
ICD-10 Finland
Vitamin B12deficiency anaemia due to selective vitamin B12malabsorption with proteinuria
304.5
29.8
30
*
215
Kela drug reimbursment
Diabetes, non-insulin-treated
1.6
29.6
918
6243
A02BX02
ATC
sucralfate; oral
2.5
29.5
245
1018
R11
ICD-10 Finland
Nausea and vomiting
2.1
29.1
342
1681
C16.3
ICD-10 Finland
Malignant neoplasm: Pyloric antrum
31.9
29.0
38
12
JAH00
NOMESCO Finland
Laparotomy
3.2
29.0
156
496
R50.9
ICD-10 Finland
Fever, unspecified
1.8
28.8
549
3240
J01MA12
ATC
levofloxacin; systemic
1.6
28.8
776
5081
C03CA01
ATC
furosemide; systemic
1.5
28.7
1491
11404
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
2.1
28.6
339
1675
E03.89
ICD-10 Finland
Other specified hypothyroidism
3.0
28.6
167
563
Z01.8
ICD-10 Finland
Other specified special examinations
1.6
28.3
780
5132
JDF11
NOMESCO Finland
Laparoscopic gastric bypass
6.7
28.3
73
111
WX302
NOMESCO Finland
Thoracal epidural anesthesy
2.5
28.2
227
928
103
Kela drug reimbursment
Diabetes, insulin-treated
1.5
28.2
1144
8288
A03FA02
ATC
cisapride; oral, rectal
2.0
28.1
393
2077
5550A
ICD-9 Finland
Regional enteritis, Small intestine
39.2
28.0
35
9
A49.9
ICD-10 Finland
Bacterial infection, unspecified
1.8
28.0
493
2834
D50
ICD-10 Finland
Iron deficiency anaemia
5.8
27.7
80
141
D51.3
ICD-10 Finland
Other dietary vitamin B12deficiency anaemia
100.7
27.7
30
*
K56.5
ICD-10 Finland
Intestinal adhesions [bands] with obstruction
4.1
27.5
111
279
E10.7
ICD-10 Finland
Type 1 diabetes mellitus, With multiple complications
4.2
27.4
106
256
326
Kela drug reimbursment
Adalimumab, golimumab, infliximab and ustekinumab (intestinal diseases)
14.1
27.0
46
33
C16.21
ICD-10 Finland
Malignant tumor of the corpus ventriculi early diffuse gastric carcinoma
75.6
26.8
30
*
SPAT1262
SPAT
Handing over of treatment supplies
1.6
26.5
715
4668
A10AE05
ATC
insulin detemir; parenteral
2.4
26.1
236
1029
R4190
NOMESCO Finland
Nutritional therapy
3.4
25.7
130
395
TPH20
NOMESCO Finland
Insertion of central venous catheter through subclavian or brachiocephalic vein
3.2
25.7
137
434
R53
ICD-10 Finland
Malaise and fatigue
1.6
25.6
832
5694
6403
FHL
Ileocal resection
58.4
25.0
29
5
D74
ICPC
Malignant neoplasm stomach
30.2
25.0
33
11
UJF02
NOMESCO Finland
Peroral enteroscopy
9.2
24.9
52
57
K91.2
ICD-10 Finland
Postsurgical malabsorption, not elsewhere classified
26.3
24.8
34
13
D52.9
ICD-10 Finland
Folate deficiency anaemia, unspecified
26.3
24.8
34
13
T50
ICPC
Metabolic, Medication/prescr/renewal
12.7
24.8
44
35
J01MA02
ATC
ciprofloxacin; systemic
1.4
24.5
1544
12165
A10AB04
ATC
insulin lispro; parenteral (insulins and analog. for injection, fast-acting)
3.2
24.3
129
407
N02BE01
ATC
paracetamol; systemic, rectal
1.5
24.1
3241
29339
2809X
ICD-9 Finland
Iron deficiency anaemias, Iron deficiency anaemia, unspecified
+∞
24.0
23
*
JDD96
NOMESCO Finland
Total gastrectomy with other reconstruction
+∞
24.0
23
*
E11.9
ICD-10 Finland
Type 2 diabetes mellitus, without complications
1.5
23.9
986
7119
XW000
NOMESCO Finland
Bone marrow biopsy
2.6
23.8
177
695
E10.3
ICD-10 Finland
Type 1 diabetes mellitus, With ophthalmic complications
4.2
23.7
91
219
WVA20
SPAT
NA
6.6
23.5
61
94
JDC20
NOMESCO Finland
Partial gastrectomy and Roux-en-Y reconstruction
21.4
23.4
34
16
K91.1
ICD-10 Finland
Postgastric surgery syndromes
33.6
23.3
30
9
R10.1
ICD-10 Finland
Pain localized to upper abdomen
1.7
23.2
550
3455
RD210
NOMESCO Finland
NA
4.3
23.1
87
206
JAH01
NOMESCO Finland
Laparoscopy
2.7
22.9
161
611
8145/3-C16.2
ICD-O-3
Carcinoma, diffuse type of body of stomach
83.9
22.7
25
*
8480/3-C16.9
ICD-O-3
Mucinous adenocarcinoma of stomach, NOS
45.2
22.3
27
6
SPAT1255
SPAT
Intravenous administration of medicine
2.1
22.3
271
1354
E53.9
ICD-10 Finland
Vitamin B deficiency, unspecified
16.8
22.2
35
21
TPH07
NOMESCO Finland
Cathetrisation of artery
1.8
22.1
409
2380
J18.9
ICD-10 Finland
Pneumonia, unspecified
1.5
22.0
1089
8143
JFB33
NOMESCO Finland
Other resection comprising small intestine and colon
15.1
21.9
36
24
8140/3-C16.0
ICD-O-3
Adenocarcinoma, NOS, of cardia, NOS
13.2
21.9
38
29
K50
ICD-10 Finland
Crohn disease [regional enteritis]
17.1
21.7
34
20
JN3AA
NOMESCO Finland
Abdominal X-ray examination without contrast
2.3
21.7
214
972
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
1.6
21.6
575
3726
8144/3-C16.9
ICD-O-3
Adenocarcinoma, intestinal type of stomach, NOS
115.6
21.6
23
*
B01AB05
ATC
enoxaparin; parenteral
1.4
21.2
1123
8503
C16.4
ICD-10 Finland
Malignant neoplasm: Pylorus
17.9
20.8
32
18
C16.03
ICD-10 Finland
Malignant tumor of cardiac diffuse carcinoma
19.5
20.8
31
16
JDW97
NOMESCO Finland
Other laparoscopic operation on stomach or duodenum
37.4
20.8
26
7
8144/3-C16.2
ICD-O-3
Adenocarcinoma, intestinal type of body of stomach
211.0
20.6
21
*
A28
ICPC
Limited function/disability NOS
1.5
20.5
695
4776
JFB20
NOMESCO Finland
Ileocaecal resection
8.3
20.4
45
55
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
1.6
20.2
562
3681
AA1AD
NOMESCO Finland
CT of head and brain
1.5
20.1
931
6848
JN3AD
NOMESCO Finland
Abdominal CT examination
1.9
19.9
290
1552
3AC01
NOMESCO Finland
NA
5.8
19.9
56
97
N02AA05
ATC
oxycodone; systemic
1.6
19.8
617
4152
2811A
ICD-9 Finland
Other deficiency anaemias, Other vitamin B12 deficiency anaemia
+∞
19.8
19
*
28009
ICD-8 Finland
Iron deficiency anaemias, Unspecified
+∞
19.8
19
*
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
1.6
19.8
586
3898
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
1.5
19.6
693
4806
TPX10
NOMESCO Finland
Implantation of vascular injection port
2.8
19.5
125
450
E66.8
ICD-10 Finland
Other obesity
2.5
19.4
157
646
SPAT1250
SPAT
Comprehensive monitoring of chronic illness
1.4
19.4
1065
8091
C16.01
ICD-10 Finland
Malignant tumor in cardia early diffuse gastric carcinoma early diffuse gastric carcinoma
31.4
19.2
25
8
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
1.4
19.1
1180
9160
E87.6
ICD-10 Finland
Hypokalaemia
2.6
19.0
137
529
A10AA01
ATC
NA
3.1
19.0
106
349
M05BA04
ATC
alendronic acid; oral
1.7
18.9
391
2354
H02AB06
ATC
prednisolone; systemic
1.4
18.8
1692
13983
2810A
ICD-9 Finland
Other deficiency anaemias, Pernicious anaemia[ANAEMIA PERNICIOSA CUM MYELOPATHIA SPINALI]
+∞
18.8
18
*
N03AX16
ATC
pregabalin; oral
1.5
18.7
798
5762
JF1BD
NOMESCO Finland
Very extensive small bowel CT
7.4
18.6
44
60
WW500
NOMESCO Finland
Blood transfusion
2.5
18.5
148
605
K29.3
ICD-10 Finland
Chronic superficial gastritis
2.5
18.5
144
580
SPAT1263
SPAT
Sampling
1.4
18.1
1470
11929
E11.8
ICD-10 Finland
Type 2 diabetes mellitus, with unspecified complications
1.7
18.0
396
2429
E27.1
ICD-10 Finland
Primary adrenocortical insufficiency
15.4
17.9
29
19
J01DB01
ATC
cefalexin; oral
1.4
17.9
2866
25812
A07DA03
ATC
loperamide; oral
2.3
17.9
173
781
JDW98
NOMESCO Finland
Other transluminal endoscopic operation on stomach or duodenum
3.7
17.8
77
209
L04AX03
ATC
methotrexate; systemic (immunosuppressants)
1.8
17.6
292
1635
JF1AB
NOMESCO Finland
Passage examination of small bowell with X-ray
4.0
17.5
70
177
JF1DG
NOMESCO Finland
Small bowel very extensive MRI with with high intensity magnet
15.6
17.5
28
18
A10BH01
ATC
sitagliptin; oral
1.7
17.4
364
2197
A04AA02
ATC
granisetron; systemic, transdermal
2.0
17.2
213
1071
138
Kela drug reimbursment
Severe anaemia associated with chronic renal failure
2.9
17.2
104
360
E0000UV
ATC
NA
1.4
17.1
1309
10495
WZC00
NOMESCO Finland
Planning of intervention or health care consultation
1.4
17.0
1021
7852
C16.5
ICD-10 Finland
Malignant neoplasm: Lesser curvature of stomach, unspecified
25.7
16.9
23
9
H3600, E103
ICD-10 Finland
NA
6.6
16.9
43
66
K29.5
ICD-10 Finland
Chronic gastritis, unspecified
2.6
16.7
127
506
2800A
ICD-9 Finland
Iron deficiency anaemias, Secondary to blood loss (chronic)
+∞
16.7
16
*
H02AB07
ATC
prednisone; oral
1.5
16.6
545
3706
A10BA02
ATC
metformin; oral
1.4
16.5
1078
8407
N17.9
ICD-10 Finland
Acute renal failure, unspecified
2.2
16.4
173
812
C16.31
ICD-10 Finland
Malignant tumor of the antrum ventriculi early diffuse gastric carcinoma
40.2
16.3
20
5
JDA55
NOMESCO Finland
Endoscopic dilatation of stomach, pylorus or anastomosis of stomach
12.2
16.3
29
24
A07EC01
ATC
sulfasalazine; oral, rectal
1.8
16.3
266
1484
WYA05
NOMESCO Finland
Emergency visit or other similar visit involving procedures
1.3
16.2
1397
11387
E000001
ATC
NA
1.5
16.2
682
4895
A41.9
ICD-10 Finland
Sepsis, unspecified
2.2
16.1
163
749
K29.7
ICD-10 Finland
Gastritis, unspecified
2.3
16.1
147
643
A41.5
ICD-10 Finland
Sepsis due to other Gram-negative organisms
2.2
16.0
160
734
6402
FHL
Small bowel resection
9.5
15.9
32
34
D51.2
ICD-10 Finland
Transcobalamin II deficiency
85.4
15.6
17
*
R06.0
ICD-10 Finland
Dyspnoea
1.4
15.5
909
6941
A07AA02
ATC
nystatin; oral
1.8
15.5
254
1418
K90.0
ICD-10 Finland
Coeliac disease
2.6
15.4
112
436
JF1AD
NOMESCO Finland
Small bowel CT
8.5
15.4
33
39
N02AX02
ATC
tramadol; systemic, rectal
1.3
15.4
1518
12603
A04
ICPC
Weakness/tiredness general
1.6
15.4
475
3180
A10AB01
ATC
insulin (human); parenteral (insulins and analog. for injection, fast-acting)
2.4
15.3
133
570
A10BB12
ATC
glimepiride; oral
1.7
15.2
340
2091
WX110
NOMESCO Finland
Local anesthesy
1.3
15.1
2142
18704
E03
ICD-10 Finland
Other hypothyroidism
2.0
15.1
201
1042
8240/3-C16.2
ICD-O-3
Neuroendocrine tumor, NOS, of body of stomach
45.1
15.0
18
*
K80.2
ICD-10 Finland
Calculus of gallbladder without cholecystitis
1.6
15.0
391
2510
E11.7
ICD-10 Finland
Type 2 diabetes mellitus, with multiple complications
1.9
14.8
235
1296
T90
ICPC
Diabetes non-insulin dependent
1.4
14.8
803
6042
K80.5
ICD-10 Finland
Calculus of bile duct without cholangitis or cholecystitis
2.4
14.8
127
541
L97
ICD-10 Finland
Ulcer of lower limb, not elsewhere classified
2.2
14.8
144
654
H02AB09
ATC
hydrocortisone; systemic
3.0
14.8
86
293
C16.22
ICD-10 Finland
Malignant tumor of the corpus ventriculi early intestinal gastric carcinoma
56.9
14.8
17
*
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
1.5
14.6
579
4098
E10.8
ICD-10 Finland
Type 1 diabetes mellitus, With unspecified complications
4.6
14.6
50
110
WX002
NOMESCO Finland
Sedation and analgesia
1.4
14.6
696
5111
B55
ICPC
Blood and Immunity, Local injection/infiltration
80.4
14.6
16
*
N18.9
ICD-10 Finland
Chronic kidney disease, unspecified
1.8
14.5
272
1586
K02.1
ICD-10 Finland
Caries of dentine
1.3
14.4
1590
13377
105
Kela drug reimbursment
Adrenal cortical hypofunction
15.4
14.4
23
15
202
Kela drug reimbursment
Connective tissue diseases, rheumatoid arthritis and comparable disease
1.6
14.3
369
2357
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
1.6
14.3
355
2246
E86
ICD-10 Finland
Volume depletion
2.3
14.2
126
548
H04AA01
ATC
glucagon; nasal, parenteral
3.4
14.1
69
208
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
1.9
14.1
208
1119
WX602
NOMESCO Finland
Repeated or continuing anesthesia shots throug a catheter
1.8
14.1
247
1409
JAP00
NOMESCO Finland
Freeing of adhesions in the peritoneal cavity
4.0
14.0
55
138
C16.0
ICD-10 Finland
Malignant neoplasm: Cardia
9.4
13.9
28
30
E10
ICD-10 Finland
Type 1 diabetes mellitus
3.7
13.9
60
164
P01AB01
ATC
metronidazole; oral, rectal
1.3
13.9
1252
10214
123
Kela drug reimbursment
Chronic disorders of vitamin D metabolism
2.6
13.9
99
383
T86
ICPC
Hypothyroidism/myxoedema
2.2
13.9
141
655
XCK10
NOMESCO Finland
Photography of fundus of eye
1.6
13.9
381
2475
E66.9
ICD-10 Finland
Obesity, unspecified
2.6
13.8
99
385
S97
ICPC
Chronic ulcer skin
1.9
13.8
209
1136
N06AX11
ATC
mirtazapine; oral
1.3
13.8
1041
8272
J02AC01
ATC
fluconazole; systemic
1.3
13.7
1176
9523
SPAT1083
SPAT
Initiation and monitoring of IV fluid therapy
2.0
13.6
175
893
A10AE06
ATC
insulin degludec; parenteral
2.9
13.6
84
297
Z71.8
ICD-10 Finland
Other specified counselling
1.4
13.6
677
5007
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
1.4
13.5
742
5582
D59.1
ICD-10 Finland
Other autoimmune haemolytic anaemias
7.9
13.5
30
38
SPAT1203
SPAT
Injection therapy, other than intramuscular or subcutaneous
2.0
13.5
170
861
K25.9
ICD-10 Finland
Gastric ulcer, Unspecified as acute or chronic, without haemorrhage or perforation
2.9
13.5
83
292
K56.7
ICD-10 Finland
Ileus, unspecified
2.9
13.5
81
283
JFA38
NOMESCO Finland
Endoscopic dilatation of small intestine
34.1
13.5
17
5
K80.0
ICD-10 Finland
Calculus of gallbladder with acute cholecystitis
1.9
13.5
185
972
UJF12
NOMESCO Finland
Enteroscopy through intestinal stoma
10.9
13.5
25
23
5559X
ICD-9 Finland
Regional enteritis, Unspecified site
140.4
13.4
14
*
A01AB09
ATC
miconazole; local oral
1.6
13.3
346
2215
K04.5
ICD-10 Finland
Chronic apical periodontitis
1.4
13.2
716
5375
C07AB07
ATC
bisoprolol; oral
1.3
13.2
1892
16416
C16.04
ICD-10 Finland
Malignant tumor of cardiac intestinal carcinoma
13.8
13.2
22
16
R13
ICD-10 Finland
Dysphagia
1.8
13.2
241
1394
J15.9
ICD-10 Finland
Bacterial pneumonia, unspecified
1.6
13.2
389
2574
K51.0
ICD-10 Finland
Ulcerative (chronic) pancolitis
5.8
13.1
36
62
SFA10
NOMESCO Finland
Fillning on one surface of tooth
1.3
13.0
1509
12726
E10.1
ICD-10 Finland
Type 1 diabetes mellitus, With ketoacidosis
6.2
13.0
34
55
Z04.8
ICD-10 Finland
Examination and observation for other specified reasons
1.6
13.0
370
2428
JN3CD
NOMESCO Finland
Abdominal CT examination both without and with contrast
2.1
13.0
144
696
E61.1
ICD-10 Finland
Iron deficiency
4.8
12.9
42
88
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.3
12.9
1182
9643
L04AB04
ATC
adalimumab; parenteral
3.5
12.9
58
165
C16.32
ICD-10 Finland
Malignant tumor of the antrum ventriculi early intestinal gastric carcinoma
50.1
12.8
15
*
E10.00
ICD-10 Finland
Insulin-dependent diabetes diabetic hypoglycemic coma
4.5
12.8
44
98
WYA30
NOMESCO Finland
Preparations for expected poor cooperation
1.7
12.8
253
1503
N02AB03
ATC
fentanyl; nasal, sublingual, transdermal
1.8
12.8
206
1144
K25.7
ICD-10 Finland
Gastric ulcer, Chronic without haemorrhage or perforation
3.7
12.8
55
151
A02BC03
ATC
lansoprazole; oral
1.3
12.7
1071
8635
T55
ICPC
Metabolic, Local injection/infiltration
32.1
12.6
16
5
A11CC03
ATC
alfacalcidol; systemic
2.5
12.5
97
392
E16.2
ICD-10 Finland
Hypoglycaemia, unspecified
3.3
12.5
62
190
K31.8
ICD-10 Finland
Other specified diseases of stomach and duodenum
5.5
12.5
36
66
JKA21
NOMESCO Finland
Laparoscopic cholecystectomy
1.6
12.5
347
2263
A02BA02
ATC
ranitidine; systemic
1.4
12.5
777
5968
SPAT1253
SPAT
Initiation, adjustment, discontinuation or repetition of medication
1.3
12.5
1046
8418
TPH90
NOMESCO Finland
Removal of fixed intravenous catheter
3.6
12.5
55
154
D13.3
ICD-10 Finland
Benign neoplasm: Other and unspecified parts of small intestine
6.6
12.5
31
47
O99.0
ICD-10 Finland
Anaemia complicating pregnancy, childbirth and the puerperium
9.3
12.4
25
27
D50.1
ICD-10 Finland
Sideropenic dysphagia
130.4
12.4
13
*
6321
FHL
Subtotal gastrectomy (also includes oment and spleen removal)
130.4
12.4
13
*
JN4AD
NOMESCO Finland
Body CT examination
1.7
12.4
260
1569
SPAT1130
SPAT
Esophagoscopy, gastroscopy and duodenoscopy
2.3
12.4
109
474
R42
ICD-10 Finland
Dizziness and giddiness
1.4
12.4
818
6345
SPAT1148
SPAT
Treatment of chronic ulcer or burn
1.5
12.4
503
3573
I50.9
ICD-10 Finland
Heart failure, unspecified
1.4
12.4
664
4973
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
1.7
12.3
246
1466
J01FF01
ATC
clindamycin; systemic
1.4
12.3
848
6619
25000
ICD-8 Finland
Diabetes mellitus, Sine complicatione
2.2
12.3
119
541
B03XA02
ATC
darbepoetin alfa; parenteral
2.8
12.2
80
293
JFA58
NOMESCO Finland
Endoscopic dilatation of colon
9.6
12.2
24
25
L01BC53
ATC
tegafur, combinations; systemic
12.4
12.1
21
17
WB121
NOMESCO Finland
Demanding neoadjuvant cytostatic therapy
3.7
12.1
52
143
JN4CD
NOMESCO Finland
Very extensive body CT
2.0
12.0
151
768
JMA10
NOMESCO Finland
Transabdominal total splenectomy
4.8
12.0
39
82
A04AA01
ATC
ondansetron; systemic, rectal
1.8
12.0
213
1224
EBA00
NOMESCO Finland
Extraction of tooth
1.3
12.0
950
7573
JDA52
NOMESCO Finland
Other endoscopic procedure using diathermy or heat in stomach or pylorus
11.0
12.0
22
20
JCA55
NOMESCO Finland
Endoscopic dilatation of oesophagus
3.6
12.0
53
149
SPAT1310
SPAT
Counselling related to known health issue
1.3
12.0
1012
8147
E10.4
ICD-10 Finland
Type 1 diabetes mellitus, With neurological complications
5.0
12.0
37
74
K92.1
ICD-10 Finland
Melaena
1.8
11.9
203
1150
NK6QA
NOMESCO Finland
Measurement of bone density from tow or more locations with X-ray
1.8
11.9
203
1151
D11
ICPC
Diarrhoea
1.6
11.8
283
1776
L98.4
ICD-10 Finland
Chronic ulcer of skin, not elsewhere classified
2.5
11.8
87
346
178
Kela drug reimbursment
Combination product containing tegafur, gimeracil and oteracil
14.7
11.8
19
13
G62.9
ICD-10 Finland
Polyneuropathy, unspecified
2.0
11.8
140
698
24409
ICD-8 Finland
Myxoedema, (hypothyreosis) NUD
8.4
11.8
25
30
D07AB02
ATC
hydrocortisone butyrate; topical
1.3
11.7
929
7403
Z01.0
ICD-10 Finland
Examination of eyes and vision
1.4
11.7
524
3795
Y83
ICD-10 Finland
Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
1.7
11.6
270
1678
R63.4
ICD-10 Finland
Abnormal weight loss
2.1
11.6
131
636
8145/3-C16.3
ICD-O-3
Carcinoma, diffuse type of gastric antrum
65.1
11.6
13
*
K44.9
ICD-10 Finland
Diaphragmatic hernia without obstruction or gangrene
1.7
11.6
255
1562
E87.1
ICD-10 Finland
Hypo-osmolality and hyponatraemia
1.9
11.5
177
971
A29
ICPC
General symptom/complaint other
1.5
11.5
389
2658
EB1AA
NOMESCO Finland
Tooth X-ray examination
1.3
11.5
1578
13537
JL5BG
NOMESCO Finland
MRI examinaiton of bile and pancreas ducts with high intesity magnet
2.6
11.5
84
332
C16.13
ICD-10 Finland
Malignant tumor of the fundus ventriculi diffuse carcinoma
120.3
11.4
12
*
D55
ICPC
Digestive, Local injection/infiltration
120.3
11.4
12
*
A06AD11
ATC
lactulose; oral
1.4
11.4
640
4823
K43.9
ICD-10 Finland
Other and unspecified ventral hernia without obstruction or gangrene
1.9
11.4
156
822
A06AC01
ATC
ispaghula (psylla seeds); oral
1.3
11.2
873
6933
A10AA02
ATC
NA
2.0
11.2
144
737
K51.9
ICD-10 Finland
Ulcerative colitis, unspecified
2.4
11.1
89
369
R07.4
ICD-10 Finland
Chest pain, unspecified
1.3
11.1
950
7651
N39.0
ICD-10 Finland
Urinary tract infection, site not specified
1.4
11.1
553
4079
R4110
NOMESCO Finland
Physiotherapy
1.3
11.1
876
6974
K25.4
ICD-10 Finland
Gastric ulcer, Chronic or unspecified with haemorrhage
3.9
11.0
44
114
WD125
NOMESCO Finland
Demanding cystostatic therapy of methastized malignancy
1.9
10.8
149
783
SFA30
NOMESCO Finland
Filling on tree or more surfaces of tooth
1.3
10.8
1129
9337
L80
ICD-10 Finland
Vitiligo
6.9
10.8
26
38
JX1LA
NOMESCO Finland
Kinetic X-ray of alimentary tract with pictures
15.5
10.8
17
11
SFA40
NOMESCO Finland
Replacement of krone of tooth
1.4
10.8
625
4735
A01AB04
ATC
amphotericin B; local oral
1.8
10.8
198
1150
N30.0
ICD-10 Finland
Acute cystitis
1.4
10.7
482
3486
K08.3
ICD-10 Finland
Retained dental root
1.7
10.7
222
1338
6318
FHL
Resection (2/3) and gastrojejunostomy (including Roux-Y)
9.6
10.7
21
22
JN5DR
NOMESCO Finland
PET-CT of upper body metabolism
3.0
10.7
59
197
K52.9
ICD-10 Finland
Noninfective gastroenteritis and colitis, unspecified
2.0
10.7
125
620
L28
ICPC
Limited function/disability (L)
1.4
10.6
606
4580
Z76.9
ICD-10 Finland
Person encountering health services in unspecified circumstances
1.7
10.6
216
1297
I10
ICD-10 Finland
Essential (primary) hypertension
1.2
10.6
2288
20624
N03AX12
ATC
gabapentin; oral
1.4
10.6
481
3492
Z93.2
ICD-10 Finland
Ileostomy status
7.0
10.5
25
36
D46.9
ICD-10 Finland
Myelodysplastic syndrome, unspecified
4.8
10.5
34
72
E10.2
ICD-10 Finland
Type 1 diabetes mellitus, With renal complications
4.8
10.5
34
72
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
1.4
10.4
544
4046
D00.2
ICD-10 Finland
Carcinoma in situ: Stomach
110.3
10.4
11
*
C16.19
ICD-10 Finland
Malignant tumor of the fundus ventriculi other or unspecified carcinoma
110.3
10.4
11
*
15199
ICD-8 Finland
Malignant neoplasm of stomach, Part unspecified
+∞
10.4
10
*
H02AA02
ATC
fludrocortisone; oral
3.5
10.4
47
136
N06AX21
ATC
duloxetine; oral
1.6
10.3
293
1919
JFF00
NOMESCO Finland
Catheter enterostomy
12.0
10.3
18
15
5551A
ICD-9 Finland
Regional enteritis, Large intestine
32.6
10.3
13
*
J01CA08
ATC
pivmecillinam; oral
1.3
10.3
1306
11057
B04AD01
ATC
NA
8.8
10.2
21
24
RD160
NOMESCO Finland
NA
9.6
10.2
20
21
A10BG03
ATC
pioglitazone; oral
2.3
10.2
94
417
P01BA02
ATC
hydroxychloroquine; oral
1.6
10.2
245
1539
K59.1
ICD-10 Finland
Functional diarrhoea
1.8
10.2
173
979
Z51.5
ICD-10 Finland
Palliative care
1.6
10.2
233
1445
I25.9
ICD-10 Finland
Chronic ischaemic heart disease, unspecified
1.4
10.1
503
3707
L01BA01
ATC
methotrexate; systemic (folic acid analog.)
2.0
10.1
131
674
E66.01
ICD-10 Finland
Obesity due to excess calories
1.8
10.1
172
979
SPAT1325
SPAT
Vaccination
1.3
10.0
1263
10678
QBJ30
NOMESCO Finland
Correction of abdominal apron
4.9
10.0
31
63
D64.8
ICD-10 Finland
Other specified anaemias
2.7
10.0
67
252
N19
ICD-10 Finland
Unspecified kidney failure
1.9
9.9
148
802
M35.0
ICD-10 Finland
Sicca syndrome [Sjögren]
2.6
9.9
69
267
D28
ICPC
Limited function/disability (D)
5.8
9.9
27
47
E83.51
ICD-10 Finland
Hypocalcemia
5.5
9.9
28
51
D06
ICPC
Abdominal pain localized other
1.6
9.9
232
1449
L01BB02
ATC
mercaptopurine; oral
4.9
9.9
31
64
K86.1
ICD-10 Finland
Other chronic pancreatitis
3.8
9.9
40
106
XJD02
NOMESCO Finland
Peroral endoscopic ultrasonography
3.7
9.9
41
111
N18.8
ICD-10 Finland
Other chronic renal failure
2.1
9.8
114
563
K90.3
ICD-10 Finland
Pancreatic steatorrhoea
4.7
9.8
32
69
D62
ICD-10 Finland
Acute posthaemorrhagic anaemia
3.5
9.7
44
128
-1
NOMESCO Finland
NA
1.3
9.7
856
6906
UJF45
NOMESCO Finland
Flexible sigmoidoscopy with biopsy
1.5
9.7
290
1925
A10BH05
ATC
linagliptin; oral
1.7
9.7
186
1096
D12.6
ICD-10 Finland
Benign neoplasm: Colon, unspecified
1.7
9.6
182
1071
R55
ICD-10 Finland
Syncope and collapse
1.4
9.6
418
3008
SPAT1301
SPAT
No procedures
1.3
9.5
1093
9123
TBW99
NOMESCO Finland
Other minor procedure in endocrine surgery
15.0
9.5
15
10
SAA02
NOMESCO Finland
Basic examination of mouth
1.2
9.4
1772
15649
384
Kela drug reimbursment
Combination product containing tegafur, gimeracil and oteracil
100.2
9.4
10
*
8145/3-C16.0
ICD-O-3
Carcinoma, diffuse type of cardia, NOS
30.1
9.4
12
*
8140/3-C16.3
ICD-O-3
Adenocarcinoma, NOS, of gastric antrum
30.1
9.4
12
*
28000
ICD-8 Finland
Iron deficiency anaemias, Posthaemorrhagica
+∞
9.4
9
*
WB113
NOMESCO Finland
Multiple adjuvant cytostatic therapy
1.9
9.4
132
705
2501B
ICD-9 Finland
Diabetes mellitus, Diabetes with ketoacidosis[DIABETES MELLITUS CUM KETOACIDOSI ,TYYPPI I]
12.3
9.3
16
13
8144/3-C16.3
ICD-O-3
Adenocarcinoma, intestinal type of gastric antrum
21.7
9.3
13
6
M05BX04
ATC
denosumab; parenteral
1.7
9.3
185
1104
H02AB02
ATC
dexamethasone; systemic
1.5
9.3
324
2225
TKC20
NOMESCO Finland
Catheterisation of bladder
1.5
9.3
274
1813
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
1.6
9.3
254
1651
QDB10
NOMESCO Finland
Major dressing of wound of skin of lower limb
1.7
9.2
172
1008
WZC30
NOMESCO Finland
Teaching
1.4
9.2
386
2756
A01
ICPC
Pain general/multiple sites
1.6
9.2
242
1559
T28
ICPC
Limited function/disability (T)
3.4
9.1
42
124
SPAT1222
SPAT
Counselling/guidance promoting independent living
1.4
9.1
558
4261
L04AC05
ATC
ustekinumab; parenteral
7.7
9.1
20
26
2449X
ICD-9 Finland
Acquired hypothyroidism, Unspecified hypothyroidism
6.2
9.1
23
37
E03.8
ICD-10 Finland
Other specified hypothyroidism
6.2
9.1
23
37
D94
ICPC
Chronic enteritis/ulcerative colitis
5.1
9.1
27
53
H36.09*E10.3
ICD-10 Finland
Insulin-dependent diabetes mellitus - Diabetic retinopathy
5.1
9.1
27
53
K29.9
ICD-10 Finland
Gastroduodenitis, unspecified
3.4
9.0
42
125
L17
ICPC
Foot/toe symptom/complaint
1.3
9.0
777
6240
RD250
NOMESCO Finland
NA
36.8
9.0
11
*
C16.02
ICD-10 Finland
Malignant tumor of cardiac early intestinal gastric carcinoma
36.8
9.0
11
*
K13.79
ICD-10 Finland
Change in the oral mucosa UNS
2.4
9.0
75
320
R56.8
ICD-10 Finland
Other and unspecified convulsions
1.8
9.0
146
821
B78
ICPC
Hereditary haemolytic anaemia
18.6
8.9
13
7
I25.1
ICD-10 Finland
Atherosclerotic heart disease
1.3
8.9
966
7996
U07
ICPC
Urine symptom/complaint other
1.7
8.9
191
1166
5351A
ICD-9 Finland
Gastritis and duodenitis, Atrophic gastritis[GASTRITIS ATROPHICANS CORPORIS (TYPUS A)]
24.0
8.9
12
5
WX704
NOMESCO Finland
Intubation
1.6
8.9
212
1329
E03.0
ICD-10 Finland
Congenital hypothyroidism with diffuse goitre
3.5
8.8
39
112
SPAT1144
SPAT
Treatment of reopened or infected surgical wound
1.6
8.8
244
1590
E10.6
ICD-10 Finland
Type 1 diabetes mellitus, With other specified complications
4.9
8.8
27
55
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
1.3
8.8
596
4622
S72.0
ICD-10 Finland
Fracture of neck of femur
1.7
8.7
189
1156
K51.8
ICD-10 Finland
Other ulcerative colitis
3.3
8.7
42
129
JC2AB
NOMESCO Finland
Oesophagus X-ray examination with contrast
3.3
8.7
42
129
E11.2
ICD-10 Finland
Type 2 diabetes mellitus, with renal complications
1.9
8.7
126
678
SFA20
NOMESCO Finland
Filling on two surfaces of tooth
1.2
8.7
1546
13534
C16.10
ICD-10 Finland
Malignant tumor of the fundus ventriculi without histology
50.1
8.7
10
*
2662A
ICD-9 Finland
Deficiency of B-complex components, Other B-complex deficiencies[HYPOVITAMINOSIS B12]
50.1
8.7
10
*
C16.6
ICD-10 Finland
Malignant neoplasm: Greater curvature of stomach, unspecified
50.1
8.7
10
*
1514C
ICD-9 Finland
Malignant neoplasm of stomach, Body of stomach[MAHASYÖPÄ, CORPORIS DIFFUUSI KARSINOOMA]
50.1
8.7
10
*
O99.2
ICD-10 Finland
Endocrine, nutritional and metabolic diseases complicating pregnancy, childbirth and the puerperium
4.5
8.6
29
65
N06AB04
ATC
citalopram; systemic
1.3
8.6
683
5419
TK800
NOMESCO Finland
Hemodialysis
2.4
8.6
72
307
E55.9
ICD-10 Finland
Vitamin D deficiency, unspecified
5.2
8.6
25
48
A03DA02
ATC
pitofenone and analgesics; systemic
2.1
8.6
95
462
WZB00
NOMESCO Finland
Telephone receipt or other advice
1.3
8.5
742
5963
J45.9
ICD-10 Finland
Asthma, unspecified
1.3
8.5
561
4330
E66.00
ICD-10 Finland
Metabolic syndrome
1.8
8.5
142
804
JFF10
NOMESCO Finland
Loop enterostomy
4.0
8.5
32
80
T44
ICPC
Metabolic, Preventive immunization/medic
27.6
8.5
11
*
L95
ICPC
Osteoporosis
1.9
8.5
116
612
S52.5
ICD-10 Finland
Fracture of lower end of radius
1.5
8.5
308
2138
WX892
NOMESCO Finland
Monitored bed care
1.5
8.4
241
1590
E87.5
ICD-10 Finland
Hyperkalaemia
2.3
8.4
71
307
R10.0
ICD-10 Finland
Acute abdomen
2.0
8.4
98
487
D59.9
ICD-10 Finland
Acquired haemolytic anaemia, unspecified
7.9
8.3
18
23
28008
ICD-8 Finland
Iron deficiency anaemias, Alia definita
+∞
8.3
8
*
K52.88
ICD-10 Finland
Other specified noninfective gastroenteritis and colitis
2.3
8.3
76
340
JDC10
NOMESCO Finland
Partial gastrectomy and gastrojejunostomy
10.7
8.3
15
14
WX404
NOMESCO Finland
Intravenous generell anesthesy
1.3
8.3
604
4734
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
1.5
8.2
304
2117
D01
ICPC
Abdominal pain/cramps general
1.5
8.2
268
1817
SPAT1217
SPAT
Assessment of need for services (elderly/care support)
1.5
8.2
322
2266
K57.3
ICD-10 Finland
Diverticular disease of large intestine without perforation or abscess
1.3
8.2
618
4867
A07EA02
ATC
hydrocortisone; rectal
2.3
8.2
73
323
JAD10
NOMESCO Finland
Repair of incisional hernia
3.6
8.2
35
98
E11
ICD-10 Finland
Type 2 diabetes mellitus
1.4
8.2
503
3841
ZX114
SPAT
NA
7.5
8.1
18
24
SPAT1100
SPAT
Long-term monitoring of blood pressure
1.5
8.1
269
1829
SAA01
NOMESCO Finland
Simple examination of mouth
1.2
8.1
2005
18105
EBA05
NOMESCO Finland
Complicated extraction of tooth
1.4
8.1
495
3778
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.2
8.1
1427
12456
M07.4*K50.9
ICD-10 Finland
Arthropathy in Crohn's disease [regional enteritis]
11.7
8.1
14
12
I63.9
ICD-10 Finland
Cerebral infarction, unspecified
1.4
8.0
449
3375
ZXA10
NOMESCO Finland
Bilateral
1.3
8.0
645
5126
D37.7
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Other digestive organs
2.1
8.0
91
448
R51.80
ICD-10 Finland
Headache
1.4
8.0
368
2672
JDF01
NOMESCO Finland
Laparoscopic gastroplasty
6.3
8.0
20
32
NK4XE
NOMESCO Finland
Joint ultrasound examination not elsewhere classified
1.7
8.0
162
977
D87
ICPC
Stomach function disorder
7.2
7.9
18
25
KMAK
NOMESCO Finland
NA
1.2
7.9
1424
12444
2500B
ICD-9 Finland
Diabetes mellitus without mention of complication[DIABETES MELLITUS SINE COMPLICATIONE ,TYYPPI I]
2.6
7.9
56
221
H3603, E103
ICD-10 Finland
NA
3.8
7.9
31
81
ND2AA
NOMESCO Finland
Hand and fingers X-ray examination
1.6
7.9
222
1455
ZXA05
NOMESCO Finland
Left side
1.3
7.9
921
7674
JFA15
NOMESCO Finland
Endoscopic polypectomy in colon
1.7
7.9
168
1027
H36.00
ICD-10 Finland
Diabetic background retinopathy
2.8
7.9
50
183
Z03.80
ICD-10 Finland
Observation for other suspected diseases and conditions
2.1
7.9
88
432
J01DA09
ATC
[U] cefadroxil; inhalant, oral
1.3
7.9
836
6889
H05AA02
ATC
teriparatide; parenteral
5.1
7.8
23
45
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.2
7.8
1475
12950
SFC01
NOMESCO Finland
Adjuvant procedure of filling therapy
1.3
7.8
693
5578
ZXC86
NOMESCO Finland
Use of endoscopic device
4.3
7.8
27
63
K91.8
ICD-10 Finland
Other postprocedural disorders of digestive system, not elsewhere classified
10.8
7.8
14
13
Z01.2
ICD-10 Finland
Dental examination
1.2
7.8
1060
8993
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
1.5
7.8
288
2006
WX290
NOMESCO Finland
Other blockade of nerve
1.2
7.7
1029
8703
R06AE07
ATC
cetirizine; oral
1.2
7.7
1269
10983
JN1CG
NOMESCO Finland
Extensive MRI examination of upper part of abdomen with high intensity magnet
2.2
7.7
77
358
M05.8
ICD-10 Finland
Other seropositive rheumatoid arthritis
1.6
7.7
171
1054
XF603
NOMESCO Finland
Direct intraarterial blood pressure measurement
1.8
7.7
120
667
A12AA04
ATC
calcium carbonate; oral
2.5
7.7
57
231
UKC02
NOMESCO Finland
Cystoscopy
1.3
7.6
613
4868
Z46.8
ICD-10 Finland
Fitting and adjustment of other specified devices
2.1
7.6
86
422
N29
ICPC
Neurological sympt/complt other
2.4
7.6
61
258
A10BD03
ATC
metformin and rosiglitazone; systemic
2.5
7.6
57
232
D07AC01
ATC
betamethasone; topical
1.2
7.6
1091
9305
205
Kela drug reimbursment
Chronic hypertension
1.2
7.6
1212
10453
SPAT1104
SPAT
Monitoring of emergency patient
1.5
7.6
218
1436
K04.1
ICD-10 Finland
Necrosis of pulp
1.5
7.6
236
1585
N06AX03
ATC
mianserin; oral
1.7
7.5
161
984
5609X
ICD-9 Finland
Intestinal obstruction without mention of hernia, Unspecified intestinal obstruction
5.4
7.5
21
39
BEF00
NOMESCO Finland
Continuous subcutaneous glucose monitoring
5.4
7.5
21
39
56096
ICD-8 Finland
Intestinal obstruction without mention of hernia, Ileus propter adhaesionem (functione laesa circulationis intestinalis non indicata)
5.4
7.5
21
39
SAA03
NOMESCO Finland
Extended examination of mouth
1.2
7.5
998
8435
B28
ICPC
Limited function/disability (B)
4.3
7.5
26
61
SPAT1149
SPAT
Suture or treatment of traumatic wound
1.4
7.5
410
3073
K22.2
ICD-10 Finland
Oesophageal obstruction
2.9
7.5
43
149
M06.9
ICD-10 Finland
Rheumatoid arthritis, unspecified
1.9
7.5
100
527
B99
ICD-10 Finland
Other and unspecified infectious diseases
2.2
7.5
73
339
N03AX09
ATC
lamotrigine; oral
2.0
7.4
89
448
R41.8
ICD-10 Finland
Other and unspecified symptoms and signs involving cognitive functions and awareness
1.4
7.4
313
2239
R52.2
ICD-10 Finland
Other chronic pain
2.0
7.4
91
464
2859X
ICD-9 Finland
Other and unspecified anaemias, Anaemia, unspecified[ANAEMIA NUD]
5.3
7.4
21
40
A10BX04
ATC
[U] exenatide; parenteral
3.3
7.3
35
108
N06AA09
ATC
amitriptyline; systemic
1.4
7.3
328
2371
2780A
ICD-9 Finland
Obesity and other hyperalimentation, Obesity
3.7
7.3
30
82
C03DA01
ATC
spironolactone; oral
1.4
7.3
402
3014
H02AB04
ATC
methylprednisolone; systemic
1.3
7.3
471
3620
SGA02
NOMESCO Finland
Opening and dilatation of root canal of tooth
1.4
7.3
300
2133
K81.0
ICD-10 Finland
Acute cholecystitis
2.1
7.3
74
348
1512C
ICD-9 Finland
Malignant neoplasm of stomach, Pyloric antrum[MAHASYÖPÄ, ANTRI PYLORI DIFFUUSI KARSINOOMA]
+∞
7.3
7
*
JFK10
NOMESCO Finland
Freeing of adhesions in intestinal obstruction
4.5
7.2
24
54
L30.9
ICD-10 Finland
Dermatitis, unspecified
1.3
7.2
502
3904
D63.8
ICD-10 Finland
Anaemia in other chronic diseases classified elsewhere
5.8
7.2
19
33
N05AH04
ATC
quetiapine; oral
1.4
7.1
419
3176
SPAT1240
SPAT
Therapeutic discussion
1.5
7.1
212
1409
D53.9
ICD-10 Finland
Nutritional anaemia, unspecified
30.0
7.1
9
*
Z80.0
ICD-10 Finland
Family history of malignant neoplasm of digestive organs
3.9
7.1
27
69
1370
FHL
Colonoscopy, whole colon
3.8
7.1
28
74
AN1
HP
Coronary angiography
1.3
7.1
443
3387
K55.8
ICD-10 Finland
Other vascular disorders of intestine
6.6
7.1
17
26
C01DA02
ATC
glyceryl trinitrate; oral, oral aerosol, sublingual, transdermal
1.2
7.1
998
8485
R19.8
ICD-10 Finland
Other specified symptoms and signs involving the digestive system and abdomen
2.7
7.1
46
173
NFJ54
NOMESCO Finland
Internal fixation of fracture of upper femur with intramedullary nail
2.1
7.1
78
383
177
Kela drug reimbursment
Insulin glargine 300 U / ml
2.3
7.1
60
262
EBA30
NOMESCO Finland
Excision of root of tooth
1.6
7.1
158
980
H01CB02
ATC
octreotide; parenteral
6.0
7.1
18
30
EKA10
NOMESCO Finland
Biopsy of cheek
2.2
7.0
67
307
E11.4
ICD-10 Finland
Type 2 diabetes mellitus, with neurological complications
1.9
7.0
92
480
E11.00
ICD-10 Finland
Non-insulin dependent diabetes diabetic hypoglycaemic coma
1.7
7.0
139
834
E10.5
ICD-10 Finland
Type 1 diabetes mellitus, With peripheral circulatory complications
4.7
7.0
22
47
SPAT1249
SPAT
Treatment-related counselling outside office
1.2
7.0
1219
10595
SPAT1260
SPAT
Consultation of another employee
1.3
6.9
549
4350
XJW99
NOMESCO Finland
Other investigative procedure on digestive system
5.1
6.9
20
39
WX000
NOMESCO Finland
Monitoring vital functions without anesthesy
1.8
6.9
113
638
K80.8
ICD-10 Finland
Other cholelithiasis
2.4
6.9
56
239
JFB30
NOMESCO Finland
Right hemicolectomy
2.4
6.9
56
239
Y0599
ICD-8 Finland
Investigation of digestive system
2.1
6.9
74
358
Z03.89
ICD-10 Finland
Observation for other suspected diseases and conditions
1.4
6.9
342
2519
K85
ICD-10 Finland
Acute pancreatitis
2.2
6.9
66
302
JFB96
NOMESCO Finland
Other partial excision of intestine
13.8
6.9
11
8
CJE20
NOMESCO Finland
Phakoemulsification with implantation of artificial lens in posterior chamber
1.2
6.9
1356
11918
J01DA01
ATC
[U] cefalexin; systemic
1.2
6.9
2205
20266
J01MA14
ATC
moxifloxacin; systemic
1.4
6.8
279
1985
160
Kela drug reimbursment
exenatide
2.3
6.8
56
241
E89.00
ICD-10 Finland
Postirradiation hypothyroidism
3.1
6.8
34
109
UJK02
NOMESCO Finland
ERCP
1.9
6.8
95
510
J01EA01
ATC
trimethoprim; systemic
1.2
6.8
923
7810
R41.0
ICD-10 Finland
Disorientation, unspecified
1.7
6.8
121
702
B03XA03
ATC
methoxy polyethylene glycol-epoetin beta; parenteral
4.2
6.8
24
58
L01BB01
ATC
NA
9.3
6.8
13
14
K74.6
ICD-10 Finland
Other and unspecified cirrhosis of liver
2.8
6.8
40
143
A03
ICPC
Fever
1.4
6.8
344
2545
L88
ICPC
Rheumatoid/seropositive arthritis
1.8
6.8
108
606
Z02.7
ICD-10 Finland
Issue of medical certificate
1.6
6.8
177
1142
WYA10
NOMESCO Finland
First aid or other corresponding healthcare contact
1.5
6.7
200
1331
K90.8
ICD-10 Finland
Other intestinal malabsorption
16.7
6.7
10
6
KH1AE
NOMESCO Finland
Urinary tract ultrasound examination
1.6
6.7
183
1192
D69.6
ICD-10 Finland
Thrombocytopenia, unspecified
2.3
6.7
58
256
318
Kela drug reimbursment
Teriparatide
4.3
6.7
23
54
SGB10
NOMESCO Finland
Fiiling of rooth of tooth with one root channel
1.4
6.7
307
2229
I69.3
ICD-10 Finland
Sequelae of cerebral infarction
1.4
6.7
303
2199
E13.9
ICD-10 Finland
Other specified diabetes mellitus, without complications
3.1
6.7
34
111
C01DA08
ATC
isosorbide dinitrate; oral, oral aerosol, sublingual, transdermal
1.2
6.7
982
8378
SPAT1216
SPAT
Assessment of functional ability
1.3
6.7
570
4562
NFB20
NOMESCO Finland
Primary partial prosthetic replacement of hip joint using cement, other or unspecified
1.8
6.7
113
648
SGC00
NOMESCO Finland
Local medication of root channels of tooth
1.5
6.6
231
1592
JL5AG
NOMESCO Finland
Simple MRI examinaiton of bile and pancreas ducts with high intesity magnet
2.9
6.6
36
123
D10
ICPC
Vomiting
1.8
6.6
99
543
E11.3
ICD-10 Finland
Type 2 diabetes mellitus, with ophthalmic complications
1.9
6.6
91
484
E05.0
ICD-10 Finland
Thyrotoxicosis with diffuse goitre
2.0
6.6
79
401
P03
ICPC
Feeling depressed
1.6
6.6
169
1084
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
1.2
6.6
914
7751
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
1.6
6.6
169
1087
SPAT1281
SPAT
Other administrative function
1.5
6.6
216
1472
K31.9
ICD-10 Finland
Disease of stomach and duodenum, unspecified
12.2
6.6
11
9
F32.9
ICD-10 Finland
Depressive episode, unspecified
1.4
6.6
271
1933
K13.74
ICD-10 Finland
Lichen rubs planus in the mouth
2.7
6.5
40
147
203
Kela drug reimbursment
Chronic asthma and similar chronic obstructive pulmonary diseases
1.3
6.5
643
5239
M79.2
ICD-10 Finland
Neuralgia and neuritis, unspecified
2.1
6.5
67
320
K83.0
ICD-10 Finland
Cholangitis
2.3
6.5
54
234
WD105
NOMESCO Finland
Cystostatic therapy of methastized malignancy
1.7
6.5
115
665
2448A
ICD-9 Finland
Acquired hypothyroidism, Other specified acquired hypothyroidism[HYPOTHYREOSIS POST THYREOIDITIDEM]
10.0
6.5
12
12
M14.6*E10.6
ICD-10 Finland
Insulin-dependent diabetes mellitus - Diabetic neuropathic
10.0
6.5
12
12
SPAT1229
SPAT
Assessment of need for aid
1.4
6.5
287
2072
306
Kela drug reimbursment
Erythropoietin and darbepoetin
4.8
6.5
20
42
GD1ED
NOMESCO Finland
Extensive high resolution CT examination of lungs
1.9
6.5
88
465
Z98.8
ICD-10 Finland
Other specified postsurgical states
2.7
6.5
42
157
6480A
ICD-9 Finland
Other current conditions in the mother classifiable elsewhere but complicating pregnancy, childbirth and the puerperium, Diabetes mellitus
4.1
6.5
23
56
NH3AA
NOMESCO Finland
Foot and toes X-ray examination
1.5
6.5
209
1419
E05.9
ICD-10 Finland
Thyrotoxicosis, unspecified
2.0
6.5
76
384
M81.4
ICD-10 Finland
Drug-induced osteoporosis
5.0
6.5
19
38
N18.0
ICD-10 Finland
End-stage renal disease
2.5
6.5
49
200
SPAT1284
SPAT
Extensive health certificate
1.9
6.5
82
426
M06.0
ICD-10 Finland
Seronegative rheumatoid arthritis
1.9
6.5
84
440
O24.0
ICD-10 Finland
Diabetes mellitus in pregnancy: Pre-existing diabetes mellitus, insulin-dependent
3.8
6.5
25
66
L13.0
ICD-10 Finland
Dermatitis herpetiformis
4.5
6.4
21
47
5608A
ICD-9 Finland
Intestinal obstruction without mention of hernia, Other specified intestinal obstruction[OBSTRUCTIO INTESTINALIS ,ADHESIONES INTRAABDOMINALE]
4.5
6.4
21
47
R4120
NOMESCO Finland
Occupational therapy
1.5
6.4
181
1189
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
1.3
6.4
506
4008
FB1BD
NOMESCO Finland
Extensive CT examination of arteria pulmonalis
1.5
6.4
227
1571
R33
ICD-10 Finland
Retention of urine
1.4
6.4
303
2213
UJC12
NOMESCO Finland
Flexible oesophagoscopy
3.0
6.4
33
109
L40.0
ICD-10 Finland
Psoriasis vulgaris
1.7
6.4
114
666
M32.9
ICD-10 Finland
Systemic lupus erythematosus, unspecified
3.6
6.4
26
72
D07AC13
ATC
mometasone; topical
1.2
6.4
876
7418
M81.9
ICD-10 Finland
Osteoporosis, unspecified
1.6
6.3
136
836
JWW96
NOMESCO Finland
Other reoperation in gastroenterological surgery
6.5
6.3
15
23
S29
ICPC
Skin symptom/complaint other
1.3
6.3
504
3996
I84.2
ICD-10 Finland
Internal hemorrhoids without complication
1.5
6.3
230
1602
K29.6
ICD-10 Finland
Other gastritis
2.5
6.3
46
187
F45.4
ICD-10 Finland
Persistent somatoform pain disorder
2.6
6.3
43
169
ZJX00
NOMESCO Finland
Double balloon technique in gastroenterological endoscopy
11.0
6.3
11
10
K04.4
ICD-10 Finland
Acute apical periodontitis of pulpal origin
1.5
6.3
199
1344
M32.8
ICD-10 Finland
Other forms of systemic lupus erythematosus
9.3
6.3
12
13
24200
ICD-8 Finland
Thyrotoxicosis with or without goitre, Cum struma diffusa et exophthalmo. Morbus Basedowi
9.3
6.3
12
13
JDC97
NOMESCO Finland
Laparoscopic partial gastrectomy with other reconstruction
18.0
6.3
9
5
1300
FHL
Esophagogastroduodenoscopy (also includes staining)
2.4
6.3
48
199
N08.39*E10.2
ICD-10 Finland
Insulin-dependent diabetes mellitus - Diabetic nephropathy
3.8
6.3
24
63
ND1AA
NOMESCO Finland
Wrist X-ray examination
1.6
6.3
164
1062
JFA60
NOMESCO Finland
Stricturoplasty in small intestine
+∞
6.2
6
*
JD003
NOMESCO Finland
Adjuvant radiotherapy of gastric or duodenal tumor
+∞
6.2
6
*
E31.08
ICD-10 Finland
Autoimmune polyglandular failure
+∞
6.2
6
*
28199
ICD-8 Finland
Other vitamin B12 deficiency anaemia, Other and unspecified deficiency anaemia
+∞
6.2
6
*
A10BB01
ATC
glibenclamide; oral
1.5
6.2
222
1539
D69.3
ICD-10 Finland
Idiopathic thrombocytopenic purpura
3.3
6.2
28
84
E87.2
ICD-10 Finland
Acidosis
4.3
6.2
21
49
M54.9
ICD-10 Finland
Dorsalgia, unspecified
1.4
6.2
304
2235
B01AB10
ATC
tinzaparin; parenteral
1.5
6.2
208
1424
D99
ICPC
Disease digestive system other
2.8
6.2
36
128
K91.4
ICD-10 Finland
Colostomy and enterostomy malfunction
6.3
6.1
15
24
SGA04
NOMESCO Finland
Very demanding opening and dilatation of root canal of tooth
1.5
6.1
222
1542
JN3DG
NOMESCO Finland
Very extensive MRI examination with high intensity magnet
5.3
6.1
17
32
ZX121
NOMESCO Finland
Central venous catheter
5.7
6.1
16
28
TJD00
NOMESCO Finland
Insertion of nasogastric or naso-gastroduodenal tube
2.4
6.1
48
203
JKB00
NOMESCO Finland
Incision of bile duct
4.6
6.1
19
41
WZA90
NOMESCO Finland
Other doctors statement
1.3
6.1
589
4789
NA2AA
NOMESCO Finland
Thoracal spine X-ray examination without contrast
1.9
6.1
77
401
N05AX08
ATC
risperidone; systemic
1.4
6.1
274
1989
S22
ICPC
Nail symptom/complaint
1.5
6.1
171
1126
KBV02
NOMESCO Finland
Cystoscopic insertion of stent into ureter
2.0
6.1
70
351
K07
ICPC
Swollen ankles/oedema
1.6
6.1
151
967
XF402
NOMESCO Finland
ECG with work load test
1.4
6.0
349
2640
R2130
NOMESCO Finland
Counselling and guidance which enhance independent living
1.4
6.0
232
1632
R00.1
ICD-10 Finland
Bradycardia, unspecified
1.6
6.0
131
807
S18
ICPC
Laceration/cut
1.2
6.0
1341
11888
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
1998
9179
3.09
292.78
3.2
2.0
3.2
2.9
mg/l
5.14
1765
7637
1290
5413
2.93
210.77
3.0
2.3
11.7
12.8
umol/l
6.55
1196
4947
2596
15434
2.58
209.42
3.1
2.0
81.1
93.6
pmol/l
26.52
1582
7892
1206
5009
2.91
199.44
2.9
2.3
2.4
2.3
g/l
6.85
1126
4581
2339
13481
2.51
198.00
4.5
2.5
128.8
147.8
ug/l
1.31
2167
12176
1600
7848
2.60
189.36
2.1
1.8
1135.5
1164.1
nmol/l
0.59
1258
5746
1118
4668
2.85
181.06
3.0
2.4
20.2
23.1
%
8.26
924
3903
1514
8124
2.29
138.46
2.3
1.7
15057828.3
27327431.4
pmol/l
0.50
1222
6532
967
4251
2.62
137.55
2.8
2.3
1.8
1.7
%
1.16
844
3684
1597
8978
2.20
128.38
1.9
1.5
20.8
20.4
nmol/l
0.50
1414
7585
947
4684
2.29
100.65
5.5
5.1
1.0
1.0
mmol/l
0.02
885
4277
714
3172
2.48
96.48
2.7
2.4
70.2
67.1
e9/l
0.60
562
2388
2305
15944
1.90
95.57
7.0
4.4
33.9
34.8
g/l
12.19
2156
14612
2064
14171
1.83
83.89
3.2
2.2
76.6
79.3
nmol/l
4.35
1878
12398
2533
18669
1.80
79.81
8.6
6.4
1.2
1.2
mmol/l
3.46
2145
15581
431
1640
2.80
78.99
1.9
1.7
1.5
1.5
g/l
0.64
357
1389
678
3235
2.29
76.74
3.0
2.0
0.2
0.2
g/l
2.56
632
2984
2221
15898
1.77
75.87
7.3
5.7
25.5
26.6
%
4.17
2079
14582
2177
15503
1.77
75.62
7.2
5.6
2.9
2.8
%
0.44
2038
14273
85
86
10.05
74.66
2.6
1.3
2.0
2.0
umol/l
0.14
79
80
2184
15653
1.76
73.43
7.1
5.5
58.9
58.3
%
1.31
2044
14438
2308
16865
1.74
71.92
7.5
5.6
1.2
1.2
mmol/l
2.08
2098
15076
1016
5793
1.97
71.50
3.5
2.9
0.8
0.8
mmol/l
7.00
950
5314
2327
17084
1.74
70.94
7.3
5.5
0.2
0.2
e9/l
0.18
2040
14736
2299
16867
1.73
69.85
7.2
5.4
1.7
1.9
e9/l
6.65
2032
14583
299
1002
3.12
68.67
1.6
1.4
243.9
272.6
ug/g
1.67
201
589
2434
18453
1.68
62.83
8.0
5.7
12.3
12.1
umol/l
0.26
2310
17425
1611
11057
1.71
59.67
3.1
2.4
59.8
58.9
u/l
0.26
1484
10122
752
4136
1.98
57.45
3.8
3.9
262.8
251.0
u/l
0.51
706
3876
2500
19443
1.63
55.40
10.9
8.4
4.2
4.3
e9/l
0.82
2209
16792
1005
6146
1.81
55.08
1.4
1.2
2.4
1.5
u/ml
0.77
222
1578
712
3936
1.96
53.28
4.8
3.8
14.1
23.5
ug/l
0.99
613
3235
76
105
7.34
52.07
2.9
1.2
28.1
30.0
umol/l
0.61
71
100
541
2741
2.10
51.48
1.9
1.6
—
—
—
0
0
881
5348
1.80
48.79
1.5
1.5
2.7
2.5
g/l
0.89
482
3103
614
3324
1.98
48.51
3.9
2.0
217.7
144.1
ug/g
3.65
518
2565
318
1327
2.50
47.83
4.4
3.2
1203.3
4393.1
u/ml
0.78
275
1125
669
3777
1.90
46.54
3.5
2.5
8.2
9.4
umol/l
1.10
591
3290
1454
10254
1.61
45.53
3.9
3.0
36.8
37.9
u/l
0.14
1379
9668
3174
26920
1.59
42.90
10.8
7.2
88.1
80.7
u/l
9.85
3009
25081
2019
15527
1.54
42.46
10.6
10.4
1.3
1.3
inr
1.34
543
4268
224
840
2.75
41.77
1.7
1.5
—
—
—
0
0
527
2880
1.94
40.09
4.2
3.5
106.9
90.4
ng/l
2.59
435
2407
525
2883
1.93
39.32
2.0
2.1
380.5
378.5
nmol/l
0.07
472
2607
566
3266
1.84
36.19
6.8
6.2
11.0
10.9
mmol/l
0.09
535
3065
2558
21168
1.47
34.83
6.4
4.5
7.2
6.8
mmol/l
8.53
2442
19841
194
750
2.66
34.07
3.9
3.0
256.8
944.0
u/ml
1.01
176
688
1981
15933
1.43
29.36
5.0
4.0
—
—
—
0
0
1615
12636
1.43
27.30
3.7
3.3
2.3
2.4
mmol/l
10.29
1409
10797
570
3580
1.68
26.62
5.2
3.3
1.5
2.0
mmol/l
2.16
452
2867
1185
8791
1.47
26.44
5.0
3.7
84.9
86.3
%
1.06
1163
8554
2900
25194
1.41
26.42
5.2
4.0
16.2
13.7
mm/h
10.88
2696
22989
243
1185
2.11
25.16
1.4
1.2
—
—
—
0
0
520
3234
1.69
25.14
2.3
2.5
65.6
66.1
g/l
0.70
468
2896
565
3595
1.65
25.01
5.2
3.3
5.8
5.8
kpa
0.73
551
3473
317
1707
1.92
24.86
6.6
3.4
23.6
24.3
mmol/l
2.66
295
1508
136
520
2.66
24.47
1.3
1.2
—
—
—
0
0
497
3125
1.66
22.95
3.6
2.3
36.1
53.5
u/l
0.56
428
2642
896
6444
1.49
22.92
2.1
1.8
—
—
—
0
0
695
4754
1.54
22.53
8.5
6.1
104.5
104.3
mmol/l
0.60
677
4631
383
2256
1.76
22.45
2.9
2.7
10.7
10.6
g/l
0.05
346
2032
97
325
3.03
22.31
1.3
1.1
53.4
58.3
u/l
0.48
65
222
2722
23730
1.36
22.11
6.2
5.0
4760.4
2198.4
e6/l
0.76
51
391
110
399
2.80
21.94
3.7
3.2
7.1
19.2
nmol/l
0.42
105
388
650
4418
1.55
21.62
7.2
6.3
0.9
1.1
mmol/l
0.76
483
3398
2330
19949
1.34
20.65
3.7
3.0
59.0
52.6
u/l
1.58
2156
18116
507
3293
1.61
20.47
8.0
5.9
1.4
1.4
mmol/l
0.65
485
3149
2843
25094
1.35
20.46
5.4
4.0
15.2
15.0
pmol/l
2.59
2568
22347
1419
11287
1.37
20.26
2.2
2.1
193.4
229.0
u/l
0.64
1333
10480
467
3005
1.62
19.56
4.3
2.8
4.4
4.5
kpa
0.12
453
2890
639
4432
1.51
19.21
7.3
6.3
5.0
5.1
kpa
0.38
599
4191
308
1785
1.78
19.06
1.9
1.8
1.4
1.4
g/l
0.05
272
1598
638
4431
1.51
19.05
7.3
6.3
12.2
12.0
kpa
0.34
601
4188
33
56
5.93
18.68
3.7
3.0
6.7
6.4
mg/l
0.11
27
47
1098
8467
1.39
18.67
3.0
2.3
—
—
—
0
0
386
2399
1.66
18.53
3.8
3.6
5.1
5.2
kpa
0.93
349
2188
1405
11300
1.35
18.26
4.0
3.3
93.7
100.9
e6/l
0.08
1121
8759
332
1991
1.72
18.21
9.9
8.8
—
—
—
0
0
175
854
2.09
18.13
1.8
1.7
—
—
—
0
0
369
2289
1.67
17.84
3.6
3.5
1.4
1.9
mmol/l
1.63
248
1649
177
873
2.07
17.83
1.6
1.6
0.4
16.2
iu/ml
1.16
37
201
780
5708
1.44
17.76
2.0
1.9
30.2
30.1
s
0.19
759
5524
146
672
2.21
17.56
2.3
2.2
33.1
33.3
umol/l
0.02
113
545
531
3617
1.53
17.28
7.9
7.0
114.3
120.8
g/l
11.32
514
3479
265
1515
1.80
17.17
1.9
2.4
—
—
—
0
0
265
1515
1.80
17.17
1.9
2.4
7.4
7.4
g/l
0.12
192
1107
264
1512
1.79
17.00
1.9
2.4
3.7
3.8
g/l
0.15
187
1062
224
1227
1.87
16.67
2.6
3.3
5.9
1.8
ratio
0.65
13
91
157
760
2.10
16.64
1.6
1.3
—
—
—
0
0
228
1258
1.85
16.58
2.6
3.3
37.5
62.0
mg/l
1.37
188
1035
1357
10983
1.33
16.56
3.6
3.1
6.8
7.1
mmol/l
2.18
1132
9068
228
1261
1.85
16.46
2.6
3.3
58.2
64.8
mg/l
0.33
189
1034
249
1418
1.80
16.35
2.0
2.4
10.5
10.4
g/l
0.24
207
1192
364
2301
1.63
16.32
1.5
1.5
—
—
—
0
0
244
1396
1.79
15.77
2.0
2.4
3.2
3.1
g/l
0.64
191
1087
59
182
3.27
15.68
1.3
1.1
91.0
85.9
u/l
0.18
51
158
1724
14521
1.30
15.54
13.1
9.6
0.0
0.0
e9/l
0.94
1393
11775
1388
11351
1.32
15.54
4.5
3.9
11.4
8.8
mg/mmol
1.10
913
7088
376
2427
1.60
15.47
1.8
1.7
—
—
—
0
0
57
174
3.30
15.41
1.3
1.1
25.5
21.6
u/l
0.28
49
147
147
721
2.07
15.08
1.1
1.1
11.1
7.7
u/ml
0.24
15
67
1020
8007
1.35
15.03
3.0
2.6
5.1
5.3
e6/l
0.16
906
6998
1960
16837
1.29
15.02
4.7
3.9
0.0
0.0
estimate
0.00
367
3080
1553
12944
1.30
15.01
4.8
3.8
138.3
120.1
e6/l
0.30
1173
9373
171
889
1.96
14.92
1.8
1.4
14.8
15.4
iu/ml
0.03
11
20
201
1104
1.86
14.85
1.8
2.3
0.0
0.1
g/l
0.80
180
1005
759
5691
1.40
14.84
24.5
28.5
1.4
1.5
inr
0.48
106
768
960
7483
1.36
14.77
4.6
3.9
315.4
508.0
ng/l
0.63
796
6283
60
195
3.10
14.66
1.8
1.8
—
—
—
0
0
223
1271
1.79
14.62
2.0
2.4
0.5
1.0
g/l
1.83
191
1076
1314
10742
1.31
14.55
3.7
3.2
432.9
305.1
mg/l
0.46
884
6738
189
1029
1.87
14.37
1.9
2.4
0.0
0.0
g/l
0.50
168
936
1978
17076
1.28
14.35
4.7
4.0
0.0
0.0
estimate
0.80
355
3041
615
4470
1.43
14.31
2.1
1.7
—
—
—
0
0
186
1014
1.87
14.09
1.9
2.4
0.0
0.0
g/l
0.00
167
933
1456
12152
1.29
13.60
3.2
3.0
2199.3
1763.2
ng/l
2.59
1286
10489
1947
16856
1.27
13.52
6.4
5.3
0.0
0.0
estimate
0.50
372
3082
606
4462
1.41
13.05
2.1
1.7
—
—
—
0
0
1252
10291
1.30
13.04
3.9
3.2
0.6
0.5
e6/l
0.30
976
7861
285
1795
1.63
12.97
3.1
3.2
4.1
4.4
pmol/l
6.22
249
1554
202
1172
1.76
12.50
1.8
2.2
36.5
37.4
g/l
1.28
174
988
763
5878
1.36
12.45
3.7
3.0
3.4
2.4
e6/l
1.32
435
3272
3565
33369
1.31
12.42
24.5
15.9
28.2
26.0
mg/l
2.92
3097
27138
1699
14588
1.26
12.28
4.5
4.0
51.9
72.0
ng/l
0.74
1325
10881
23
42
5.50
12.10
1.8
1.6
223.1
23.8
pmol/l
2.78
18
33
34
88
3.88
11.79
1.2
1.2
—
—
—
0
0
914
7298
1.32
11.60
3.9
3.0
2.5
2.5
mmol/l
0.65
800
6360
1113
9165
1.28
11.13
3.1
2.7
2624.9
6198.5
umol/l
3.30
937
7735
18
28
6.45
11.08
1.4
1.0
8.7
343484.6
nmol/l
0.48
13
23
151
839
1.83
10.84
2.6
2.2
3.5
3.7
g/l
0.63
139
801
171
988
1.76
10.78
1.9
1.7
—
—
—
0
0
346
2386
1.49
10.52
4.3
3.1
118.1
128.3
g/l
12.40
335
2332
175
1026
1.73
10.49
2.9
3.1
23.8
25.0
mmol/l
3.05
152
894
294
1965
1.53
10.38
9.9
8.0
23.8
24.3
mmol/l
2.01
273
1807
904
7308
1.30
10.34
1.7
1.6
1.7
1.4
mg/l
1.14
713
5663
48
169
2.86
10.30
1.4
1.3
—
—
—
0
0
49
176
2.80
10.15
1.7
1.5
—
—
—
0
0
49
176
2.80
10.15
1.7
1.5
—
—
—
0
0
252
1637
1.57
10.11
4.9
4.9
1.6
1.6
%
0.37
241
1536
118
620
1.93
10.10
2.0
1.6
0.7
0.8
nmol/l
0.22
103
508
496
3687
1.39
10.01
3.3
2.9
285.5
241.1
ng/l
0.87
453
3350
48
172
2.81
9.99
1.4
1.3
—
—
—
0
0
115
602
1.93
9.96
3.6
3.6
59.8
58.4
%
0.50
115
602
149
847
1.78
9.95
1.8
1.5
0.2
0.2
g/l
1.63
139
797
3252
30368
1.25
9.88
6.6
4.8
2.0
2.1
mu/l
0.31
2962
27192
182
1097
1.69
9.88
1.6
1.6
275.7
282.8
titre
0.02
14
57
12
13
9.25
9.87
2.2
1.6
—
—
—
0
0
224
1427
1.60
9.78
4.2
3.8
24.4
24.8
mmol/l
1.09
203
1281
152
878
1.76
9.63
3.1
2.9
8.0
7.8
kpa
0.70
144
809
785
6284
1.30
9.60
3.4
2.8
1.5
1.2
e6/l
0.95
454
3641
354
2497
1.45
9.59
6.2
6.3
24.3
24.6
mmol/l
0.72
332
2326
151
877
1.75
9.39
1.8
1.5
1.1
1.2
g/l
0.48
142
826
249
1643
1.55
9.34
1.9
1.9
—
—
—
0
0
246
1619
1.55
9.34
4.9
5.0
0.9
0.9
%
0.03
236
1519
90
443
2.05
9.29
1.7
1.4
—
—
—
0
0
46
168
2.76
9.26
1.2
1.1
80.0
86.6
u/l
0.24
36
125
46
169
2.74
9.16
1.2
1.1
20.4
29.8
u/l
0.99
37
123
135
768
1.78
9.03
1.4
1.2
4.7
6.9
u/ml
0.40
25
137
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
213
1369
1.58
8.98
3.0
2.6
0.3
0.3
u/ml
0.04
117
783
90
449
2.02
8.97
1.7
1.4
—
—
—
0
0
52
206
2.54
8.94
1.5
1.5
3.4
7.9
u/l
1.38
23
95
141
816
1.75
8.90
1.4
1.2
12.8
41.8
u/ml
1.49
12
53
89
447
2.01
8.72
1.7
1.4
—
—
—
0
0
88
441
2.01
8.68
1.7
1.4
—
—
—
0
0
118
653
1.83
8.66
1.4
1.3
—
—
—
0
0
88
442
2.01
8.63
1.7
1.4
—
—
—
0
0
88
442
2.01
8.63
1.7
1.4
—
—
—
0
0
242
1616
1.53
8.62
1.9
1.9
3.9
2.2
ug/l
0.88
217
1381
50
199
2.53
8.53
1.3
1.1
—
—
—
0
0
60
260
2.32
8.52
1.4
1.3
—
—
—
0
0
105
564
1.88
8.47
4.2
4.5
1635.8
3529.4
iu/ml
0.25
19
75
145
860
1.71
8.41
2.2
2.1
121.3
129.0
g/l
2.53
106
620
263
1810
1.48
8.12
4.2
2.4
0.7
0.6
%
1.15
254
1731
226
1511
1.52
8.02
1.9
1.8
—
—
—
0
0
650
5198
1.29
7.92
1.3
1.3
33.5
36.4
iu/ml
0.19
183
1638
112
629
1.80
7.87
1.2
1.2
10.3
3.8
u/ml
0.33
13
49
16
32
5.01
7.65
1.0
1.1
87.4
75.2
ug/l
—
10
23
57
256
2.24
7.50
1.4
1.3
—
—
—
0
0
371
2757
1.38
7.49
1.7
1.7
1.5
1.5
%
0.00
316
2361
128
759
1.71
7.47
1.4
1.2
3.5
3.6
u/ml
0.03
19
72
143
881
1.64
7.24
2.3
2.3
80.7
104.7
ug/min
0.44
87
526
102
574
1.79
7.16
1.4
1.2
47.2
40.7
u/ml
0.14
14
66
3650
34881
1.23
7.10
28.2
18.8
139.3
139.6
mmol/l
8.80
3553
33858
138
847
1.65
7.10
6.0
6.8
105.1
105.1
mmol/l
0.02
128
753
133
809
1.66
7.08
2.7
2.7
1.8
1.7
mg/l
0.85
121
714
1084
9306
1.22
6.98
5.2
4.3
0.0
0.0
estimate
1.08
343
2947
50
220
2.29
6.93
1.2
1.2
92.5
117.9
titre
0.27
12
38
48
210
2.30
6.75
1.1
1.0
294.8
289.4
mg/l
0.16
40
182
195
1314
1.51
6.72
1.5
1.8
35.6
38.7
u/l
1.51
159
1132
408
3131
1.33
6.70
4.4
3.5
1.2
1.2
mmol/l
3.54
355
2693
3652
34956
1.22
6.70
28.5
18.9
4.0
4.0
mmol/l
0.51
3550
33875
11
9
12.25
6.57
1.2
1.1
369.0
303.0
nmol/l
—
11
9
136
850
1.62
6.54
2.3
2.0
89.5
90.2
%
0.12
129
800
127
781
1.64
6.51
2.8
2.2
192.5
197.8
%
0.26
118
745
320
2377
1.37
6.50
10.0
7.7
0.7
0.7
%
0.35
315
2358
101
584
1.75
6.50
3.0
3.6
1.8
1.5
%
0.24
76
433
149
954
1.58
6.48
1.3
1.2
—
—
—
0
0
148
947
1.58
6.46
1.3
1.2
—
—
—
0
0
249
1775
1.43
6.44
1.2
1.2
221.2
135.0
iu/ml
1.98
97
648
282
2059
1.39
6.37
3.6
2.8
0.3
0.3
e6/l
0.60
276
2012
896
7610
1.22
6.36
5.2
4.5
1.0
1.0
kg/l
0.13
154
1189
320
2388
1.37
6.32
9.9
7.6
1.2
1.3
%
3.00
313
2370
32
120
2.68
6.23
1.8
2.2
47.9
141.4
umol/l
2.09
23
71
34
132
2.59
6.19
3.5
2.9
93.8
69.6
mg/l
0.53
29
90
42
184
2.29
5.93
1.1
1.1
—
—
—
0
0
42
184
2.29
5.93
1.1
1.1
—
—
—
0
0
70
375
1.88
5.82
1.1
1.1
1.5
1.5
g/l
0.04
62
333
23
75
3.08
5.76
1.0
1.2
258.4
268.9
pmol/l
0.05
12
55
42
187
2.26
5.72
1.1
1.1
—
—
—
0
0
42
187
2.26
5.72
1.1
1.1
—
—
—
0
0
42
187
2.26
5.72
1.1
1.1
—
—
—
0
0
19
55
3.46
5.72
1.2
1.5
121.6
129.0
ng/l
0.09
19
55
1449
12988
1.17
5.50
5.2
4.3
—
—
—
0
0
81
465
1.76
5.41
5.5
5.9
12.1
12.2
mg/l
0.05
70
422
3053
28950
1.16
5.39
26.8
17.1
36.7
38.6
%
16.14
1858
18571
66
359
1.85
5.27
1.3
1.2
9.3
52.2
u/ml
—
6
22
16
44
3.65
5.20
1.8
1.4
—
—
—
0
0
78
451
1.74
5.11
1.3
1.3
0.5
0.3
nmol/l
—
7
28
59
313
1.90
5.10
1.4
1.2
—
—
—
0
0
79
459
1.73
5.09
1.8
1.4
—
—
—
0
0
264
1985
1.35
5.02
4.6
3.2
24.6
25.2
mmol/l
1.87
256
1930
60
322
1.87
5.02
1.1
1.1
3.5
2.4
u/ml
0.30
16
115
24
88
2.74
4.93
2.0
1.5
0.4
0.4
ug/l
0.32
16
51
77
452
1.72
4.80
7.8
6.2
8.0
7.5
mmol/l
0.40
59
373
122
804
1.53
4.78
1.6
1.9
14.1
12.4
mg/l
0.41
106
737
129
863
1.51
4.71
1.7
1.5
—
—
—
0
0
133
899
1.49
4.63
1.9
1.7
—
—
—
0
0
187
1350
1.40
4.60
1.4
1.3
—
—
—
0
0
55
297
1.86
4.55
1.5
1.3
1.1
1.5
nmol/l
1.60
47
266
106
686
1.56
4.52
1.4
1.6
—
—
—
0
0
55
298
1.86
4.50
1.3
1.5
—
—
—
0
0
46
238
1.94
4.33
1.0
1.0
—
—
—
0
0
54
295
1.84
4.32
1.1
1.1
—
—
—
0
0
182
1324
1.39
4.30
2.8
2.6
—
—
—
0
0
38
184
2.07
4.29
2.2
1.9
627.1
660.2
e6/l
0.11
20
80
472
3910
1.23
4.23
4.3
3.6
—
—
—
0
0
75
455
1.66
4.19
1.2
1.1
122.1
83.6
iu/ml
0.35
13
88
66
387
1.72
4.18
1.3
1.3
485.8
272.9
pmol/l
0.44
44
291
37
181
2.05
4.09
2.1
3.1
—
—
—
0
0
2793
26549
1.13
4.07
30.8
19.2
14.5
13.8
%
66.21
2736
25856
15
47
3.20
4.05
2.5
2.3
—
—
—
0
0
51
283
1.81
3.92
1.1
1.1
—
—
—
0
0
3210
30824
1.14
3.88
7.5
6.2
42.2
40.6
mmol/mol
12.50
2936
27987
121
835
1.46
3.86
1.8
1.5
—
—
—
0
0
71
435
1.64
3.85
1.3
1.2
326.9
271.9
u/ml
0.84
41
262
575
4903
1.20
3.85
1.3
1.2
20.0
12.9
u/ml
0.90
197
1803
159
1154
1.39
3.85
1.2
1.2
2.5
1.0
u/ml
0.36
12
111
37
186
2.00
3.82
2.5
2.5
—
—
—
0
0
22
89
2.48
3.79
1.4
1.2
144.5
128.5
nmol/l
0.12
17
65
124
864
1.45
3.78
1.4
1.3
—
—
—
0
0
124
864
1.45
3.78
1.4
1.3
—
—
—
0
0
120
832
1.45
3.75
2.9
2.4
15.7
16.0
%
0.31
68
421
126
1771
0.70
3.74
1.7
1.8
—
—
—
0
0
75
470
1.61
3.73
1.3
1.2
—
—
—
0
0
60
355
1.70
3.72
1.8
1.5
—
—
—
0
0
3606
34938
1.15
3.69
15.0
10.6
23.5
25.0
u/l
3.65
3474
33340
139
994
1.41
3.68
3.2
3.2
0.9
0.8
nmol/l
0.59
96
761
57
335
1.71
3.63
1.8
1.5
—
—
—
0
0
60
360
1.68
3.55
3.5
3.0
—
—
—
0
0
25
111
2.26
3.54
1.3
1.3
—
—
—
0
0
36
185
1.95
3.52
1.4
1.3
—
—
—
0
0
36
185
1.95
3.52
1.4
1.3
—
—
—
0
0
187
1416
1.33
3.49
3.8
3.5
1.5
1.4
mmol/l
0.30
181
1390
11
31
3.55
3.48
1.4
1.3
—
—
—
0
0
1825
17013
1.12
3.47
2.8
2.5
—
—
—
0
0
90
602
1.50
3.40
1.3
1.2
101.1
38.4
u/l
0.90
81
516
49
282
1.75
3.38
2.2
1.3
48.8
28.5
iu/ml
—
6
12
20
82
2.45
3.37
2.5
1.9
—
—
—
0
0
14
48
2.92
3.29
2.6
2.3
—
—
—
0
0
64
400
1.61
3.26
1.5
1.5
57.0
61.9
%
0.45
43
251
12
39
3.08
3.08
6.5
15.2
4.1
5.5
mmol/l
1.39
12
39
31
159
1.96
3.08
1.8
1.2
—
—
—
0
0
21
93
2.26
3.02
1.2
1.1
1623.9
1720.0
miu/ml
0.14
21
93
168
1284
1.32
2.99
1.9
2.1
433.0
708.0
ug/l
0.80
158
1207
91
628
1.46
2.99
1.9
1.5
—
—
—
0
0
30
154
1.95
2.98
1.3
1.5
—
—
—
0
0
77
514
1.51
2.98
1.5
1.3
—
19.5
—
0
13
33
176
1.88
2.94
1.5
1.5
—
—
—
0
0
33
176
1.88
2.94
1.5
1.5
—
—
—
0
0
33
176
1.88
2.94
1.5
1.5
—
—
—
0
0
33
176
1.88
2.94
1.5
1.5
—
—
—
0
0
28
141
1.99
2.94
1.0
1.1
—
—
—
0
0
31
162
1.92
2.94
1.1
1.0
—
—
—
0
0
11
35
3.15
2.92
1.0
1.2
—
—
—
0
0
69
452
1.53
2.92
1.5
1.3
109.4
121.9
u/ml
0.60
13
88
130
961
1.36
2.90
1.5
1.4
—
—
—
0
0
24
116
2.07
2.82
2.8
2.1
—
—
—
0
0
24
116
2.07
2.82
2.8
2.1
—
—
—
0
0
20
90
2.23
2.79
1.2
1.2
—
—
—
0
0
42
248
1.70
2.71
1.7
1.5
—
—
—
0
0
13
48
2.71
2.71
3.3
3.1
0.5
0.6
u/field
0.20
13
48
3198
30946
1.11
2.71
22.8
15.1
74.0
74.2
ml/min/173m2
0.20
2733
25607
43
257
1.68
2.66
1.2
1.1
—
68.7
—
0
12
25
126
1.99
2.65
1.4
1.4
2.4
3.4
mmol/l
2.13
25
116
36
205
1.76
2.64
2.1
1.3
1.5
1.2
promille
0.68
29
158
16
67
2.39
2.62
1.1
1.1
76.2
83.2
%
—
10
34
57
369
1.55
2.58
3.1
3.5
59.2
58.0
%
0.14
35
222
49
306
1.61
2.58
1.5
1.5
—
—
—
0
0
49
306
1.61
2.58
1.5
1.5
—
—
—
0
0
49
306
1.61
2.58
1.5
1.5
—
—
—
0
0
10
33
3.03
2.52
1.4
1.3
—
—
—
0
0
37
216
1.72
2.51
1.5
1.3
11.0
11.8
mmol/l
0.23
20
63
87
618
1.42
2.51
1.5
1.4
—
—
—
0
0
94
677
1.40
2.50
1.4
1.3
—
—
—
0
0
7
16
4.38
2.47
3.7
6.1
—
—
—
0
0
71
492
1.45
2.36
1.1
1.1
—
—
—
0
0
92
672
1.38
2.28
1.2
1.2
4.3
3.8
mmol/l
2.59
87
622
14
60
2.34
2.21
1.1
1.1
—
—
—
0
0
13
54
2.41
2.19
1.2
1.1
—
—
—
0
0
26
143
1.82
2.18
1.7
1.6
—
—
—
0
0
99
739
1.35
2.16
1.8
1.8
5.9
4.4
iu/l
0.42
35
240
634
7027
0.89
2.13
3.1
3.3
0.8
0.8
ug/l
0.00
446
5025
15
68
2.21
2.10
1.1
1.1
77.7
80.9
%
—
9
36
34
205
1.66
2.10
2.0
2.2
13.7
14.0
%
0.04
17
79
70
496
1.42
2.10
1.6
1.4
—
—
—
0
0
113
867
1.31
2.06
1.6
1.6
10586.8
15123.8
e6/l
0.86
79
620
413
3620
1.15
2.05
2.5
2.4
5.4
6.8
ug/l
0.96
331
3071
19
96
1.98
2.05
1.1
1.2
—
—
—
0
0
25
140
1.79
2.00
1.6
1.6
—
—
—
0
0
25
140
1.79
2.00
1.6
1.6
—
—
—
0
0
3696
36214
1.11
1.99
36.5
23.2
6.9
6.9
e9/l
0.17
3579
34898
33
201
1.65
1.98
2.0
2.2
—
—
—
0
0
31
186
1.67
1.97
2.5
1.7
27.3
8.5
umol/l
0.59
24
118
27
156
1.73
1.96
1.4
1.1
—
—
—
0
0
3693
36193
1.11
1.95
36.5
23.2
249.5
244.1
e9/l
4.21
3584
35028
35
218
1.61
1.93
2.8
1.8
2.2
2.3
u/field
0.04
30
149
11
45
2.45
1.92
1.2
1.4
70.1
74.6
%
0.20
11
39
3693
36205
1.10
1.90
36.5
23.2
4.2
4.4
e12/l
78.48
3572
34903
3693
36212
1.10
1.87
36.9
23.3
125.4
133.1
g/l
160.44
3612
35468
41
268
1.53
1.86
1.2
1.2
—
—
—
0
0
72
526
1.37
1.85
1.7
1.4
1264.1
2373.6
e6/l
1.49
55
386
69
501
1.38
1.84
1.9
1.5
—
—
—
0
0
27
160
1.69
1.81
1.1
1.2
—
—
—
0
0
88
666
1.33
1.81
1.5
1.4
1096.6
1237.9
e6/l
0.07
79
549
40
262
1.53
1.81
1.5
1.3
102.0
70.0
titre
—
5
23
99
764
1.30
1.78
1.3
1.3
476.6
559.9
mg/l
1.80
91
718
54
378
1.43
1.77
2.6
2.1
2.7
2.0
u/field
0.39
29
128
166
1364
1.23
1.77
1.0
1.0
—
—
—
0
0
52
362
1.44
1.76
1.1
1.1
—
—
—
0
0
39
257
1.52
1.73
1.5
1.4
29.5
31.5
u/l
0.13
31
212
105
821
1.29
1.72
1.3
1.3
34.8
33.5
iu/l
0.13
85
698
17
89
1.91
1.69
1.6
2.1
31.4
29.4
%
0.17
17
80
87
665
1.31
1.69
1.4
1.4
13.5
26.2
e6/l
0.57
75
521
57
409
1.40
1.65
2.0
1.5
—
—
—
0
0
45
309
1.46
1.65
2.1
1.6
27.7
25.6
u/ml
—
10
74
31
196
1.59
1.65
1.2
1.3
3.0
1.3
u/ml
0.24
15
104
24
142
1.69
1.64
1.4
1.1
—
—
—
0
0
65
478
1.36
1.64
1.7
1.4
10839.1
65779.4
e6/l
2.39
40
285
66
488
1.36
1.61
1.5
1.3
16.0
11.5
u/l
1.34
54
387
68
506
1.35
1.60
2.2
1.8
88.0
89.4
%
0.71
68
500
8
32
2.50
1.59
1.0
1.0
—
—
—
0
0
73
552
1.33
1.55
1.6
1.4
—
—
—
0
0
40
273
1.47
1.53
1.5
1.4
280.0
420.0
titre
—
7
28
59
433
1.37
1.52
1.9
1.6
—
—
—
0
0
50
690
0.72
1.51
1.5
1.5
—
—
—
0
0
40
274
1.46
1.51
2.0
2.1
609.6
601.9
ml
0.05
28
171
17
94
1.81
1.47
1.6
2.1
9313.4
10064.3
e6/l
—
7
55
68
515
1.33
1.45
2.1
2.1
35.5
23.4
mg/l
0.99
26
116
6
22
2.73
1.43
1.2
1.1
—
—
—
0
0
26
166
1.57
1.37
2.2
2.6
41.0
39.4
%
0.16
12
59
482
4392
1.11
1.35
4.8
4.7
34.4
33.3
%
1.34
350
2828
13
68
1.91
1.33
1.2
1.1
—
—
—
0
0
13
68
1.91
1.33
1.3
1.2
—
—
—
0
0
85
673
1.27
1.33
1.1
1.1
—
—
—
0
0
100
809
1.24
1.30
1.7
1.5
—
—
—
0
0
6
24
2.50
1.30
1.0
1.0
—
—
—
0
0
8
34
2.35
1.29
1.1
4.6
—
—
—
0
0
31
210
1.48
1.27
1.6
1.5
—
—
—
0
0
194
1676
1.16
1.27
1.3
1.3
250.5
203.3
u/ml
0.24
183
1529
8
35
2.29
1.26
1.0
1.7
—
—
—
0
0
25
163
1.54
1.22
1.2
1.1
—
—
—
0
0
144
1219
1.19
1.21
4.1
3.7
3.9
3.9
mmol/l
0.28
129
1130
23
148
1.56
1.19
1.3
1.4
63.7
61.6
%
—
6
19
12
64
1.88
1.18
2.0
1.4
—
—
—
0
0
20
125
1.60
1.17
1.3
1.3
—
—
—
0
0
7
32
2.19
1.08
2.0
1.5
—
—
—
0
0
13
75
1.74
1.02
1.3
1.6
11.6
8.8
ug/l
0.98
13
75
28
197
1.42
0.99
2.1
2.2
282.6
147.1
ug/min
—
8
48
60
476
1.26
0.98
1.1
1.1
—
—
—
0
0
61
487
1.26
0.96
1.7
1.4
—
—
—
0
0
17
109
1.56
0.93
2.2
2.2
766.2
968.0
e6/l
0.22
11
79
22
150
1.47
0.92
1.6
1.4
1.6
5.0
%
—
5
33
72
590
1.22
0.91
2.0
1.6
360.7
307.6
mu/l
0.51
66
542
(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
24
168
1.43
0.89
1.2
1.1
—
—
—
0
0
6
29
2.07
0.89
4.2
5.4
—
—
—
0
0
14
87
1.61
0.87
1.7
1.2
—
—
—
0
0
8
43
1.86
0.87
1.1
1.1
—
—
—
0
0
905
8633
1.06
0.85
1.7
1.6
1.3
1.3
mmol/l
0.13
767
7183
419
3894
1.08
0.84
1.5
1.4
—
—
—
0
0
56
451
1.24
0.84
2.7
4.5
324.8
348.9
umol/l
0.62
46
388
102
873
1.17
0.83
1.8
1.7
4.8
3.4
mg/l
0.52
86
634
39
301
1.30
0.82
1.1
1.1
—
1.9
—
0
6
27
198
1.37
0.80
1.1
1.1
1.5
7.0
nmol/l
—
9
48
305
2806
1.09
0.79
3.4
2.7
59.7
61.4
ml/min/173m2
0.39
153
1210
0
27
0.00
0.77
0.0
1.0
—
—
—
0
0
948
9882
0.95
0.76
4.4
4.7
21.6
22.2
%
0.59
440
5248
6
34
1.77
0.76
1.8
1.3
—
—
—
0
0
164
1468
1.12
0.73
2.2
1.8
—
—
—
0
0
5
26
1.92
0.70
1.2
1.4
—
—
—
0
0
20
275
0.73
0.70
1.6
1.5
—
—
—
0
0
97
842
1.16
0.69
4.2
3.5
30.6
28.3
mg/l
0.28
64
548
448
4760
0.93
0.69
10.3
7.9
—
—
—
0
0
147
1317
1.12
0.66
2.1
1.7
—
—
—
0
0
36
285
1.27
0.66
1.1
1.1
—
21.1
—
0
5
5
28
1.79
0.66
1.2
1.1
—
—
—
0
0
52
430
1.21
0.65
2.5
1.9
57.6
2085.5
u/l
3.72
23
173
45
367
1.23
0.65
1.2
1.2
3.1
5.2
u/ml
1.06
27
157
36
287
1.26
0.63
1.8
1.7
—
—
—
0
0
15
104
1.44
0.62
1.5
1.2
—
—
—
0
0
11
71
1.55
0.62
1.2
1.1
0.6
0.7
umol/24h
—
6
35
8
50
1.60
0.61
2.3
1.1
—
—
—
0
0
18
130
1.39
0.61
1.2
1.1
—
—
—
0
0
39
316
1.24
0.60
1.6
1.4
28.4
28.8
%
0.02
25
204
8
51
1.57
0.60
1.4
1.5
—
—
—
0
0
84
732
1.15
0.60
2.2
1.7
—
—
—
0
0
8
52
1.54
0.59
1.1
1.1
—
—
—
0
0
32
254
1.26
0.59
1.1
1.0
—
—
—
0
0
0
23
0.00
0.58
0.0
1.3
—
—
—
0
0
49
409
1.20
0.58
3.7
3.6
—
—
—
0
0
19
140
1.36
0.58
1.1
1.1
—
—
—
0
0
30
237
1.27
0.58
1.1
1.2
—
—
—
0
0
6
35
1.71
0.57
1.2
1.1
1.3
1.7
umol/24h
—
6
35
6
36
1.67
0.56
1.0
1.1
—
—
—
0
0
174
1593
1.10
0.55
3.8
3.7
53.1
71.2
u/ml
0.55
169
1530
20
150
1.33
0.55
1.0
1.0
1.2
1.1
u/l
—
7
81
15
203
0.74
0.51
1.7
1.5
—
—
—
0
0
38
315
1.21
0.50
2.1
1.5
—
—
—
0
0
6
41
1.46
0.50
1.2
1.2
—
—
—
0
0
211
1962
1.08
0.49
2.0
2.1
12.4
11.8
nmol/l
0.46
190
1680
12
86
1.40
0.44
1.1
1.1
—
—
—
0
0
381
3997
0.95
0.44
1.4
1.4
—
—
—
0
0
13
95
1.37
0.43
1.2
1.5
—
2029800.0
—
0
5
10
140
0.71
0.43
1.4
1.5
—
—
—
0
0
22
175
1.26
0.43
1.1
1.0
—
—
—
0
0
44
377
1.17
0.43
1.2
1.2
2.0
4.2
u/ml
1.09
22
119
12
87
1.38
0.42
1.1
1.1
—
—
—
0
0
12
87
1.38
0.42
1.1
1.1
—
—
—
0
0
5
33
1.52
0.41
1.4
2.3
13.2
19.3
umol/l
—
5
33
0
16
0.00
0.41
0.0
1.0
—
—
—
0
0
31
260
1.19
0.39
2.7
5.2
50.3
48.0
u/ml
—
8
72
10
71
1.41
0.39
1.7
1.6
—
—
—
0
0
25
206
1.21
0.37
4.6
3.6
—
—
—
0
0
30
355
0.84
0.37
1.3
1.3
7.4
7.7
mmol/l
0.19
22
250
59
524
1.13
0.37
1.1
1.3
255.3
211.0
miu/ml
0.32
20
217
3127
31531
0.97
0.37
4.7
4.6
1.4
1.5
mmol/l
7.24
2843
28351
3160
31854
0.97
0.36
4.7
4.6
4.3
4.5
mmol/l
45.51
2902
28862
6
43
1.40
0.35
1.3
1.1
—
—
—
0
0
6
86
0.70
0.33
3.0
2.9
—
—
—
0
0
29
248
1.17
0.31
1.1
1.0
692.6
662.5
ng/l
0.14
18
153
29
248
1.17
0.31
1.1
1.0
246.6
314.9
ng/l
0.85
18
158
3251
32277
1.02
0.31
5.3
4.9
6.2
6.0
mmol/l
6.45
2924
28734
12
93
1.29
0.30
1.1
1.1
—
—
—
0
0
29
250
1.16
0.29
1.1
1.0
28.5
44.9
ng/l
1.72
18
156
33
377
0.87
0.29
1.0
1.1
—
—
—
0
0
17
139
1.22
0.29
1.2
1.1
—
—
—
0
0
11
85
1.29
0.28
1.1
1.1
—
—
—
0
0
84
777
1.08
0.27
1.3
1.4
—
—
—
0
0
38
338
1.13
0.26
1.4
1.3
161592.8
118059.5
e6/l
0.12
26
236
9
72
1.25
0.25
1.2
1.2
—
—
—
0
0
25
216
1.16
0.25
2.2
1.4
—
—
—
0
0
13
105
1.24
0.24
2.5
2.1
—
—
—
0
0
3026
30450
0.98
0.24
4.2
4.1
1.3
1.3
mmol/l
0.88
2725
27106
12
96
1.25
0.24
1.6
1.3
25.5
24.8
%
—
6
12
25
217
1.15
0.24
2.2
1.4
—
—
—
0
0
24
208
1.15
0.24
1.5
1.9
—
—
—
0
0
3258
32754
0.98
0.23
5.4
5.2
2.4
2.6
mmol/l
35.26
2974
29520
11
88
1.25
0.22
1.7
1.8
0.7
1.3
ug/l
1.20
11
83
31
345
0.90
0.20
1.2
1.1
0.3
1.8
u/ml
1.77
12
132
11
133
0.83
0.19
1.0
1.2
—
—
—
0
0
6
51
1.18
0.19
1.0
1.0
—
—
—
0
0
60
560
1.07
0.18
2.4
1.7
—
—
—
0
0
46
425
1.08
0.18
1.5
1.5
—
—
—
0
0
38
349
1.09
0.17
1.1
1.1
115.1
114.0
%
0.07
32
307
5
67
0.75
0.17
1.0
1.2
—
—
—
0
0
10
120
0.83
0.16
1.0
1.0
—
—
—
0
0
6
79
0.76
0.15
1.3
2.4
76.7
161.3
nmol/l
—
6
69
9
82
1.10
0.15
1.2
1.4
—
—
—
0
0
9
82
1.10
0.15
1.1
1.1
—
—
—
0
0
11
129
0.85
0.14
5.8
5.1
—
60.0
—
0
27
82
856
0.96
0.13
1.2
1.2
—
—
—
0
0
63
660
0.95
0.11
1.4
1.4
112.1
213.8
pmol/l
2.00
63
640
190
1854
1.03
0.11
1.3
1.3
42.6
52.6
au/ml
—
7
80
33
309
1.07
0.10
1.5
1.3
8.8
12.4
u/l
1.57
27
286
27
251
1.08
0.10
2.1
1.4
—
—
—
0
0
5
47
1.06
0.09
1.0
1.0
—
—
—
0
0
16
176
0.91
0.09
1.3
1.5
59.5
67.9
%
0.65
11
143
58
558
1.04
0.08
1.8
1.7
57.0
44.7
nmol/l
2.30
58
532
22
236
0.93
0.08
1.6
1.5
—
—
—
0
0
7
68
1.03
0.07
1.0
1.6
—
—
—
0
0
12
133
0.90
0.07
1.3
1.4
89.8
68.2
pmol/l
—
5
43
16
173
0.92
0.06
1.7
1.7
—
—
—
0
0
79
811
0.97
0.06
2.3
1.7
—
—
—
0
0
21
223
0.94
0.06
1.6
1.4
—
—
—
0
0
21
223
0.94
0.06
1.6
1.4
—
—
—
0
0
21
222
0.95
0.05
1.5
1.4
—
—
—
0
0
21
222
0.95
0.05
1.5
1.4
—
—
—
0
0
209
2069
1.01
0.04
2.4
2.4
31.1
26.6
au/ml
—
6
81
1235
12317
1.00
0.03
4.9
5.5
3.5
4.4
ug/l
0.61
1066
10904
18
171
1.05
0.03
1.2
1.2
—
—
—
0
0
10
92
1.09
0.03
1.1
1.1
—
—
—
0
0
14
140
1.00
0.00
1.1
1.2
1.1
1.0
ratio
—
6
46
36
364
0.99
0.00
1.1
1.1
—
—
—
0
0
16
164
0.98
0.00
1.3
1.3
6.9
6.1
mmol/l
0.81
16
156
19
189
1.01
0.00
1.1
1.0
0.1
0.4
u/ml
—
5
53
0
9
0.00
0.00
0.0
1.2
—
—
—
0
0
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
6
59
1.02
0.00
1.0
1.1
—
—
—
0
0
7
72
0.97
0.00
1.0
1.1
—
5.2
—
0
10
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
7
73
0.96
0.00
1.4
1.6
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
1.4
—
0
5
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
8
89
0.90
0.00
1.6
1.1
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
8
80
1.00
0.00
1.1
1.1
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint D3_ANAEMIA_B12_DEF and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| D3_ANAEMIA_B12_DEF | 1.482 [1.37, 1.6] | < 0.001 |
| Birth year | 0.992 [0.98, 1.0] | 0.055 |
During the follow-up period (1.1.1998 — 31.12.2019), 7706 out of 16915 females with D3_ANAEMIA_B12_DEF died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| D3_ANAEMIA_B12_DEF | 1.604 [1.46, 1.76] | < 0.001 |
| Birth year | 0.989 [0.98, 1.0] | 0.015 |
During the follow-up period (1.1.1998 — 31.12.2019), 6887 out of 13361 males with D3_ANAEMIA_B12_DEF died.
Mortality risk
Mortality risk for people of age
years, who have D3_ANAEMIA_B12_DEF.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.147% | 0.38% |
| 5 | 0.848% | 2.113% |
| 10 | 2.174% | 5.004% |
| 15 | 4.043% | 9.139% |
| 20 | 6.83% | 15.193% |
Relationships between endpoints
↥Index endpoint: D3_ANAEMIA_B12_DEF – Vitamin B12 deficiency anaemia
GWS hits: 14
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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