No definition available.
Vitamin B12 deficiency anemia due to intrinsic factor deficiency
D3_VITAMIN_B12_DEFICIENCY_ANEMIA_DUE_TO_INTRINSIC_FACTOR_DEFICIENCY
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
519972 |
1. Apply sex-specific ruleNone |
519972 |
2. Check conditionsNone |
519972 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
695 |
4. Check minimum number of eventsNone |
695 |
5. Include endpointsNone |
695 |
6. Filter based on genotype QC (FinnGen only) |
669 |
Control definitions (FinnGen only)
Controls for this endpoint are individuals that are not cases.
Similar endpoints
↥List of similar endpoints to
Vitamin B12 deficiency anemia due to intrinsic factor deficiency
based on the number of shared cases.
Similar with more cases:
- Vitamin B12 deficiency anaemia
- Nutritional anaemias
- Anaemias
- Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
- Autoimmune diseases
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
This endpoint is excluded (different definition than used in FinnGen).
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 669 | 352 | 317 |
| Unadjusted period prevalence (%) | 0.13 | 0.12 | 0.15 |
| Median age at first event (years) | 67.55 | 65.77 | 69.53 |
-FinnGen-
Age distribution of first events
-FinnGen-
Year distribution of first events
-FinnGen-
Cumulative Incidence Function
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 695
- Matched controls
- 6950
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
D51.0
ICD-10 Finland
Vitamin B12deficiency anaemia due to intrinsic factor deficiency
4503599627370496.0
307.7
694
5
107
Kela drug reimbursment
Pernicious anaemia
151.4
307.7
419
69
K29.4
ICD-10 Finland
Chronic atrophic gastritis
71.4
307.7
290
69
B81
ICPC
Anaemia vit B12/folate deficiency
82.6
307.7
435
138
B03BA03
ATC
hydroxocobalamin; parenteral
279.0
307.7
635
254
D51.9
ICD-10 Finland
Vitamin B12deficiency anaemia, unspecified
62.9
250.6
141
28
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
6.3
128.7
436
1463
T91
ICPC
Vitamin/nutritional deficiency
27.5
93.8
65
26
WVA30, ,
SPAT
9.2
92.6
124
161
D51
ICD-10 Finland
Vitamin B12deficiency anaemia
38.4
80.4
50
14
B03BA02
ATC
cyanocobalamin tannin complex; parenteral
31.6
75.9
50
17
D50.9
ICD-10 Finland
Iron deficiency anaemia, unspecified
4.9
54.8
138
332
D64.9
ICD-10 Finland
Anaemia, unspecified
4.1
52.2
179
545
E03.9
ICD-10 Finland
Hypothyroidism, unspecified
3.9
46.5
168
527
H03AA01
ATC
levothyroxine sodium; systemic
3.2
45.6
258
1075
D13.1
ICD-10 Finland
Benign neoplasm: Stomach
10.5
45.0
51
52
SPAT1256
SPAT
Intramuscular and subcutaneous injection
3.0
44.2
390
2077
A55
ICPC
General and Unspecified, Local injection/infiltration
15.4
42.8
38
26
-50
ICPC
Medication/prescr/renewal
5.5
37.3
77
154
104
Kela drug reimbursment
Thyroid insufficiency
4.2
35.8
107
290
A50
ICPC
General and Unspecified, Medication/prescr/renewal
5.4
27.3
56
111
E03.80
ICD-10 Finland
Hypothyroidism caused by autoimmune thyroiditis
9.3
27.0
33
37
E53.8
ICD-10 Finland
Deficiency of other specified B group vitamins
32.4
23.9
31
10
SPAT1254
SPAT
Administration of medicine
2.6
22.0
158
713
UJD02
NOMESCO Finland
Gastroscopy
3.9
21.5
68
190
D51.8
ICD-10 Finland
Other vitamin B12deficiency anaemias
39.6
18.7
23
6
UJF32
NOMESCO Finland
Coloscopy
2.1
18.1
230
1311
E10.9
ICD-10 Finland
Type 1 diabetes mellitus, Without complications
4.9
18.0
40
85
A10AB05
ATC
insulin aspart; parenteral
3.1
17.8
81
286
E03.89
ICD-10 Finland
Other specified hypothyroidism
4.4
17.6
45
107
UJF30
NOMESCO Finland
Ileoscopy through colon
2.8
16.6
91
356
D53.1
ICD-10 Finland
Other megaloblastic anaemias, not elsewhere classified
41.2
16.4
20
5
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
2.5
16.3
118
529
B50
ICPC
Blood and Immunity, Medication/prescr/renewal
15.8
16.3
26
17
JDA05
NOMESCO Finland
Endoscopic polypectomy in stomach or pylorus
34.3
15.8
20
6
A10AE04
ATC
insulin glargine; parenteral
2.6
14.5
92
386
-55
ICPC
Local injection/infiltration
11.7
14.4
26
23
B80
ICPC
Iron deficiency anaemia
4.9
14.1
31
65
E10.3
ICD-10 Finland
Type 1 diabetes mellitus, With ophthalmic complications
6.2
13.9
24
40
B82
ICPC
Anaemia other/unspecified
3.9
13.4
40
107
A10AE05
ATC
insulin detemir; parenteral
3.1
13.1
56
190
WVA20, ,
SPAT
4.4
13.0
33
78
D50.8
ICD-10 Finland
Other iron deficiency anaemias
6.3
13.0
22
36
S50
ICPC
Skin, Medication/prescr/renewal
13.5
12.5
21
16
T89
ICPC
Diabetes insulin dependent
3.8
11.4
35
96
E10.7
ICD-10 Finland
Type 1 diabetes mellitus, With multiple complications
4.7
10.8
25
55
B81
ICD-10 Finland
Other intestinal helminthiases, not elsewhere classified
111.6
10.4
11
*
A10AB04
ATC
insulin lispro; parenteral
4.0
10.4
29
74
D50.0
ICD-10 Finland
Iron deficiency anaemia secondary to blood loss (chronic)
3.2
9.8
38
122
R53
ICD-10 Finland
Malaise and fatigue
1.8
9.7
189
1206
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
2.0
9.6
124
693
E27.1
ICD-10 Finland
Primary adrenocortical insufficiency
101.4
9.4
10
*
N18.9
ICD-10 Finland
Chronic kidney disease, unspecified
2.4
9.3
65
285
E10
ICD-10 Finland
Type 1 diabetes mellitus
7.9
9.2
20
26
B03BA01
ATC
cyanocobalamin; nasal, systemic
37.2
9.0
11
*
T50
ICPC
Metabolic, Medication/prescr/renewal
50.6
8.7
10
*
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
1.9
8.7
120
686
SPAT1262
SPAT
Handing over of treatment supplies
1.8
8.6
135
803
2810X
ICD-9 Finland
Other deficiency anaemias, Pernicious anaemia[ANAEMIA PERNICIOSA SINE MYELOPATHIA SPINALI]
27.9
8.5
11
*
A10AA01, ,
ATC
3.8
8.4
25
67
R50.9
ICD-10 Finland
Fever, unspecified
1.9
8.2
110
622
A10AC01
ATC
insulin (human); parenteral
2.2
8.2
71
342
Z01.8
ICD-10 Finland
Other specified special examinations
1.8
8.1
153
960
A49.9
ICD-10 Finland
Bacterial infection, unspecified
2.0
8.0
100
551
S55
ICPC
Skin, Local injection/infiltration
22.3
8.0
11
5
A10AE06
ATC
insulin degludec; parenteral
3.5
7.9
27
80
D37.1
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Stomach
8.6
7.8
16
19
E11.7
ICD-10 Finland
Type 2 diabetes mellitus, with multiple complications
2.3
7.8
57
255
XW000
NOMESCO Finland
Bone marrow biopsy
2.8
7.7
39
146
215
Kela drug reimbursment
Diabetes, non-insulin-treated
1.7
7.6
171
1127
H02AB09
ATC
hydrocortisone; systemic
4.0
7.5
21
54
S97
ICPC
Chronic ulcer skin
2.3
7.5
60
280
WYA30
NOMESCO Finland
Treatment of a patient needing special arrangements
2.3
7.4
56
254
D50
ICPC
Digestive, Medication/prescr/renewal
80.9
7.4
8
*
UJF92
NOMESCO Finland
Capsular endoscopy
4.4
7.3
18
42
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
2.2
7.2
60
285
D07BA04
ATC
hydrocortisone and antiseptics; topical
2.1
7.1
66
327
E10.8
ICD-10 Finland
Type 1 diabetes mellitus, With unspecified complications
7.1
7.0
16
23
AA1AD
NOMESCO Finland
CT of head and brain
1.6
7.0
213
1510
C03CA01
ATC
furosemide; systemic
1.5
7.0
286
2169
103
Kela drug reimbursment
Diabetes, insulin-treated
1.6
6.9
207
1459
177
Kela drug reimbursment
Insulin glargine 300 U / ml
4.1
6.7
18
45
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
1.5
6.6
264
1985
T90
ICPC
Diabetes non-insulin dependent
1.6
6.6
169
1147
SPAT1100
SPAT
Long-term monitoring of blood pressure
2.1
6.6
63
316
SPAT1216
SPAT
Assessment of functional ability
1.7
6.5
136
874
8240/3-C16.9
ICD-O-3
Neuroendocrine tumor, NOS, of stomach, NOS
70.5
6.4
7
*
A04
ICPC
Weakness/tiredness general
1.8
6.4
110
671
J01MA12
ATC
levofloxacin; systemic
1.7
6.3
140
914
SPAT1250
SPAT
Comprehensive monitoring of chronic illness
1.6
6.3
196
1390
T86
ICPC
Hypothyroidism/myxoedema
2.7
6.3
33
126
H3600, E103,
ICD-10 Finland
9.4
6.3
12
13
A28
ICPC
Limited function/disability NOS
1.6
6.3
157
1057
E000001, ,
ATC
1.7
6.3
126
802
E11.9
ICD-10 Finland
Type 2 diabetes mellitus, without complications
1.6
6.3
191
1349
D51.1
ICD-10 Finland
Vitamin B12deficiency anaemia due to selective vitamin B12malabsorption with proteinuria
+∞
6.3
6
*
N03AX11
ATC
topiramate; oral
4.0
6.2
17
43
A29
ICPC
General symptom/complaint other
1.8
6.2
101
606
ZX114, ,
SPAT
5.4
6.2
17
32
SPAT1325
SPAT
Vaccination
1.5
6.0
244
1831
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
407
2478
2.55
31.60
2.9
2.1
82.87
93.14
pmol/l
2.91
239
1260
292
1524
2.58
31.50
3.0
2.2
3.44
3.24
mg/l
0.70
255
1283
246
1284
2.42
25.44
2.2
1.8
1119.50
1213.67
nmol/l
0.72
188
955
155
721
2.48
20.06
3.4
2.4
1.93
1.79
%
0.50
130
642
341
2207
2.07
19.40
4.3
2.8
151.83
137.58
ug/l
0.14
319
2003
179
946
2.20
16.95
3.5
2.5
10.87
12.10
umol/l
1.46
169
878
226
1338
2.02
15.68
2.2
1.7
966.18
9015312.97
pmol/l
0.79
180
1076
164
865
2.17
15.45
3.1
2.5
2.32
2.27
g/l
0.47
153
799
154
820
2.13
14.04
3.1
2.5
20.19
21.29
%
0.38
134
694
173
986
2.00
13.02
1.3
1.2
0.83
1.28
u/ml
1.01
35
254
72
290
2.65
12.31
2.1
1.8
1.47
1.62
g/l
0.71
51
256
312
2231
1.72
10.93
2.8
2.2
76.94
78.81
nmol/l
0.60
283
1955
337
2469
1.71
10.74
6.9
5.2
58.33
58.30
%
0.01
314
2305
229
1507
1.77
10.72
1.8
1.6
19.29
20.89
nmol/l
0.95
204
1262
46
158
3.05
10.54
1.5
1.6
—
—
—
0
0
360
2695
1.70
10.51
6.8
6.0
1.21
1.21
mmol/l
0.01
326
2428
386
2950
1.69
10.37
7.2
6.2
11.93
11.79
umol/l
0.08
356
2785
338
2507
1.68
10.07
7.3
5.4
25.55
26.31
%
0.49
318
2336
384
2949
1.68
9.98
8.0
6.8
1.22
1.21
mmol/l
0.26
332
2501
392
3047
1.66
9.55
9.6
8.6
4.28
4.19
e9/l
0.13
341
2652
60
255
2.48
9.19
1.9
1.9
—
—
—
0
0
247
1720
1.68
9.14
3.2
2.4
64.66
60.09
u/l
0.39
224
1586
26
72
3.71
8.35
2.0
1.6
—
—
—
0
0
55
236
2.44
8.26
1.9
1.8
—
—
—
0
0
26
73
3.66
8.19
2.0
1.6
—
—
—
0
0
26
73
3.66
8.19
2.0
1.6
—
—
—
0
0
26
74
3.61
8.04
2.0
1.6
—
—
—
0
0
26
74
3.61
8.04
2.0
1.6
—
—
—
0
0
26
74
3.61
8.04
2.0
1.6
—
—
—
0
0
72
361
2.11
7.50
4.2
3.9
0.98
1.85
mmol/l
1.36
50
274
76
389
2.07
7.50
4.3
3.8
5.09
5.17
kpa
0.31
71
373
332
2585
1.54
7.25
6.1
4.7
34.04
34.75
g/l
1.42
311
2388
46
200
2.39
6.74
1.6
1.2
—
—
—
0
0
93
536
1.85
6.50
2.0
2.9
66.95
66.00
g/l
0.52
80
480
229
1685
1.54
6.25
3.9
3.1
6.80
7.06
mmol/l
0.47
200
1386
18
36
5.10
6.22
1.3
1.4
—
—
—
0
0
80
446
1.90
6.20
2.1
1.7
—
—
—
0
0
83
472
1.86
6.05
2.2
1.8
350.64
381.35
nmol/l
0.79
76
426
488
4228
1.52
5.82
9.6
7.6
93.88
80.71
u/l
3.30
457
3937
118
756
1.68
5.71
6.3
5.4
1.05
1.03
mmol/l
0.23
107
691
459
3943
1.48
5.57
5.8
3.8
15.31
15.00
pmol/l
1.56
419
3503
196
1428
1.52
5.49
3.3
2.8
2563.36
7687.75
umol/l
1.28
168
1213
231
1760
1.47
5.14
4.6
3.7
9.83
9.09
mg/mmol
0.10
157
1093
16
36
4.52
5.08
1.3
1.4
—
—
—
0
0
85
514
1.74
5.06
7.8
7.3
11.75
10.89
mmol/l
0.39
79
485
30
124
2.48
4.94
2.0
1.5
—
—
—
0
0
149
1046
1.54
4.90
2.2
1.9
—
—
—
0
0
218
1658
1.46
4.85
4.1
3.1
286.30
297.83
mg/l
0.02
153
1056
312
2536
1.42
4.82
3.6
2.7
—
—
—
0
0
9
10
9.10
4.79
3.8
2.5
40588.89
31630.50
ug/l
—
9
10
24
91
2.70
4.70
1.3
1.3
—
—
—
0
0
107
702
1.62
4.69
5.4
4.7
33.13
32.57
%
0.20
85
453
432
3734
1.41
4.60
6.1
5.0
8771.71
3165.75
e6/l
—
7
75
69
404
1.79
4.59
1.9
1.7
—
—
—
0
0
87
546
1.68
4.54
2.5
2.2
0.19
0.20
g/l
1.10
80
513
78
479
1.71
4.41
4.1
3.7
117.27
85.70
ng/l
1.49
64
412
347
2906
1.39
4.36
18.3
17.9
1.47
1.33
inr
0.98
89
821
181
1353
1.46
4.34
2.9
2.5
—
—
—
0
0
47
248
1.96
4.32
3.6
3.0
4.05
4.35
pmol/l
1.40
42
213
453
3979
1.40
4.19
5.3
4.2
17.76
13.99
mm/h
3.78
421
3614
132
933
1.51
4.17
3.1
3.2
0.80
0.81
mmol/l
0.76
126
870
20
76
2.68
3.93
1.2
1.2
—
—
—
0
0
385
3318
1.36
3.86
6.4
4.9
7.30
6.75
mmol/l
2.84
366
3129
12
29
4.19
3.72
1.3
1.4
—
—
—
0
0
12
29
4.19
3.72
1.3
1.4
—
—
—
0
0
13
37
3.56
3.41
1.2
1.1
—
—
—
0
0
91
621
1.54
3.38
3.4
2.7
5.91
8.54
umol/l
2.57
81
538
18
71
2.58
3.32
1.1
1.1
206.33
308.41
u/ml
0.81
12
34
12
33
3.68
3.30
1.5
1.7
—
—
—
0
0
364
3156
1.32
3.29
3.9
3.1
62.61
52.78
u/l
0.51
334
2884
220
1782
1.34
3.16
2.3
2.1
165.76
248.97
u/l
1.00
208
1669
12
35
3.47
3.12
1.1
1.2
—
—
—
0
0
10
25
4.04
3.09
1.5
1.6
0.78
0.98
nmol/l
—
10
16
560
5199
1.40
3.04
23.5
16.9
26.50
25.68
mg/l
0.23
485
4230
256
2130
1.32
3.04
4.0
3.3
—
—
—
0
0
112
816
1.44
3.02
1.3
1.3
23.40
38.50
iu/ml
1.19
33
255
33
176
1.92
3.00
1.7
1.4
295.05
277.34
ug/g
0.21
20
106
51
312
1.68
2.97
9.0
9.5
24.18
24.86
mmol/l
0.91
46
302
45
266
1.74
2.97
1.4
1.2
298.83
136.18
iu/ml
0.98
19
101
78
531
1.53
2.94
8.1
6.6
1.40
1.39
mmol/l
0.05
72
516
30
156
1.96
2.94
1.6
1.6
—
—
—
0
0
204
1652
1.33
2.90
3.4
3.0
42.31
32.91
u/l
1.05
192
1572
38
216
1.80
2.86
1.4
2.1
38.88
38.85
u/l
0.00
32
190
8
18
4.48
2.80
1.0
1.1
—
—
—
0
0
27
138
2.00
2.78
2.0
1.6
—
—
—
0
0
7
15
4.70
2.60
2.3
1.1
-0.46
2.78
mmol/l
—
7
15
125
954
1.38
2.59
3.5
3.0
2.52
2.48
e6/l
0.02
65
520
36
208
1.77
2.59
2.8
3.7
5.92
1.86
ratio
—
5
23
578
5436
1.38
2.55
27.5
20.0
139.32
139.60
mmol/l
1.35
564
5281
5
7
7.19
2.55
2.2
3.3
0.20
0.71
u/field
—
5
7
26
136
1.95
2.53
1.5
2.7
31.65
33.08
umol/l
0.15
20
114
216
1798
1.29
2.47
4.0
3.4
18.25
102.18
e6/l
1.65
160
1399
36
213
1.73
2.40
2.8
3.8
31.07
46.15
mg/l
0.53
30
169
36
213
1.73
2.40
2.8
3.8
85.83
94.91
mg/l
0.08
30
166
578
5449
1.36
2.40
27.7
20.1
3.98
4.00
mmol/l
0.56
563
5290
515
4777
1.30
2.40
7.1
4.7
2.12
2.24
mu/l
0.19
467
4263
97
719
1.41
2.39
7.5
7.6
0.59
1.42
mmol/l
1.51
78
561
92
679
1.41
2.33
3.4
4.1
8.15
30.33
ug/l
1.06
78
581
96
715
1.40
2.31
7.5
7.6
4.94
5.06
kpa
0.66
88
681
102
774
1.37
2.20
1.3
1.3
17.55
13.10
u/ml
0.17
30
266
53
355
1.53
2.19
1.6
1.5
—
—
—
0
0
270
2340
1.25
2.16
4.7
4.0
37.05
55.35
ng/l
0.68
218
1775
9
30
3.03
2.15
1.7
1.3
—
—
—
0
0
9
30
3.03
2.15
1.7
1.3
—
—
—
0
0
95
716
1.38
2.14
7.6
7.5
11.19
11.69
kpa
0.51
88
683
13
55
2.39
2.13
1.2
1.3
—
—
—
0
0
26
146
1.81
2.09
2.4
2.5
57.81
91.51
ug/min
0.45
15
90
14
288
0.48
2.09
1.1
1.7
—
—
—
0
0
5
10
5.03
2.07
1.4
1.5
91.00
83.60
ng/l
—
5
10
8
26
3.10
2.02
2.0
2.0
—
—
—
0
0
7
21
3.36
1.97
3.0
2.9
844.43
742.71
u/ml
—
7
21
7
21
3.36
1.97
10.7
3.7
241.86
210.52
u/l
—
7
21
238
2055
1.24
1.93
4.9
3.9
200.22
149.37
e6/l
0.19
167
1491
19
99
1.95
1.92
1.3
1.3
—
—
—
0
0
5
143
0.34
1.89
1.0
1.3
—
—
—
0
0
15
72
2.11
1.87
2.7
4.7
308.70
351.39
umol/l
—
10
64
26
154
1.72
1.78
1.5
1.3
—
—
—
0
0
295
2626
1.21
1.75
2.9
2.6
—
—
—
0
0
12
54
2.24
1.74
3.1
1.9
—
—
—
0
0
9
36
2.52
1.74
2.1
2.6
—
—
—
0
0
22
125
1.78
1.73
1.5
1.2
4.88
2.87
u/ml
—
5
16
125
1013
1.29
1.73
3.0
2.8
0.82
1.23
e6/l
0.64
66
575
21
118
1.80
1.72
1.2
1.5
—
—
—
0
0
5
13
3.87
1.72
1.2
1.0
2161.40
1498.23
miu/ml
—
5
13
7
25
2.82
1.65
2.1
2.0
—
—
—
0
0
7
25
2.82
1.65
2.1
2.0
—
—
—
0
0
22
128
1.74
1.62
1.8
2.1
90.95
88.03
%
0.26
22
123
58
424
1.40
1.60
1.8
1.5
1.58
1.52
%
0.27
50
355
22
129
1.73
1.58
2.5
2.2
127.60
127.99
g/l
0.03
15
96
141
1173
1.25
1.58
5.1
4.1
558.45
225.62
ng/l
0.69
121
990
23
138
1.69
1.53
2.1
1.6
—
—
—
0
0
5
15
3.35
1.52
2.8
1.9
—
—
—
0
0
68
517
1.35
1.49
3.2
2.4
32.46
31.90
u/l
0.07
56
440
571
5463
1.25
1.49
13.8
11.0
24.69
24.28
u/l
0.10
545
5226
229
2016
1.20
1.48
3.1
3.1
2022.07
1808.76
ng/l
0.30
200
1732
15
80
1.89
1.45
2.5
2.8
30.63
24.26
mg/l
—
8
23
11
52
2.13
1.45
3.3
2.0
—
—
—
0
0
23
141
1.65
1.43
1.3
1.3
—
—
—
0
0
23
141
1.65
1.43
1.3
1.3
—
—
—
0
0
11
53
2.09
1.39
2.1
1.7
—
—
—
0
0
11
53
2.09
1.39
2.1
1.7
—
—
—
0
0
11
53
2.09
1.39
2.1
1.7
—
—
—
0
0
13
67
1.96
1.39
5.2
3.0
—
—
—
0
0
37
257
1.46
1.36
1.9
2.5
—
—
—
0
0
24
151
1.61
1.36
1.5
1.4
0.31
0.13
iu/ml
—
5
36
20
120
1.69
1.35
1.8
2.3
210.15
194.44
%
0.29
20
115
18
105
1.73
1.34
1.1
1.1
—
—
—
0
0
13
68
1.93
1.34
1.5
1.3
2122.50
130460.22
e6/l
—
6
41
8
34
2.37
1.29
2.0
1.8
—
—
—
0
0
8
34
2.37
1.29
2.0
1.8
—
—
—
0
0
19
114
1.69
1.29
1.4
1.4
—
—
—
0
0
8
36
2.24
1.24
1.0
1.0
—
—
—
0
0
91
742
1.26
1.23
2.2
1.8
—
—
—
0
0
34
238
1.45
1.23
1.4
1.3
—
—
—
0
0
16
93
1.74
1.22
2.4
1.5
—
—
—
0
0
16
93
1.74
1.22
2.4
1.5
—
—
—
0
0
21
132
1.61
1.21
2.2
1.6
—
—
—
0
0
27
181
1.51
1.20
1.3
1.2
—
—
—
0
0
296
2706
1.16
1.18
4.2
4.1
0.00
0.00
estimate
-0.00
44
480
27
182
1.50
1.17
1.3
1.2
—
—
—
0
0
186
1641
1.18
1.15
3.6
3.3
0.21
0.58
e6/l
3.80
135
1259
8
39
2.06
1.15
1.1
1.1
—
—
—
0
0
8
39
2.06
1.15
1.1
1.1
—
—
—
0
0
228
2048
1.17
1.14
3.7
3.5
2.35
2.35
mmol/l
0.05
198
1770
17
103
1.67
1.13
6.2
1.9
62.15
58.87
%
0.22
17
103
14
80
1.77
1.13
1.4
1.3
1174.67
1310.81
e6/l
—
9
58
7
30
2.35
1.12
1.6
1.1
4.86
6.77
u/l
—
7
24
8
40
2.01
1.12
1.1
1.1
—
—
—
0
0
8
40
2.01
1.12
1.1
1.1
—
—
—
0
0
8
40
2.01
1.12
1.1
1.1
—
—
—
0
0
16
98
1.65
1.04
2.2
1.7
—
—
—
0
0
5
22
2.28
1.03
1.2
1.1
—
—
—
0
0
71
576
1.26
1.02
6.0
3.4
0.90
2.03
mmol/l
1.53
63
464
290
2671
1.15
1.01
5.8
5.5
0.00
0.00
estimate
-0.00
50
488
290
2674
1.15
0.99
4.3
4.1
0.00
0.00
estimate
0.50
54
537
71
579
1.25
0.98
8.6
8.5
115.00
119.87
g/l
1.39
71
565
581
5632
1.19
0.96
35.1
24.7
37.94
39.29
%
5.28
537
5209
581
5632
1.19
0.96
35.0
24.5
244.22
242.45
e9/l
0.24
559
5470
509
4885
1.16
0.95
7.6
6.3
42.75
40.62
mmol/mol
4.14
473
4470
581
5634
1.19
0.94
34.9
24.5
4.27
4.39
e12/l
5.62
557
5453
581
5634
1.19
0.94
35.2
24.7
126.54
132.54
g/l
15.81
565
5521
145
1276
1.17
0.93
3.0
2.6
4.66
5.09
e6/l
0.22
129
1151
6
28
2.15
0.91
1.0
1.4
—
—
—
0
0
34
255
1.35
0.88
2.6
3.4
79.41
5586.09
u/ml
0.80
29
220
6
30
2.01
0.87
1.7
1.3
1.43
1.16
promille
—
6
25
11
64
1.73
0.86
1.1
1.3
0.70
0.58
nmol/l
0.53
11
58
8
45
1.79
0.84
1.5
1.2
—
81.83
—
0
6
11
65
1.70
0.82
1.8
1.3
—
—
—
0
0
6
32
1.88
0.82
2.3
1.5
—
—
—
0
0
6
32
1.88
0.82
2.3
1.5
—
—
—
0
0
0
26
0.00
0.78
0.0
2.0
—
13.48
—
0
26
24
174
1.39
0.77
3.4
3.1
0.94
0.87
nmol/l
0.31
16
138
5
24
2.09
0.74
1.2
1.2
—
—
—
0
0
5
24
2.09
0.74
1.2
1.0
65.40
688.05
u/l
—
5
19
5
24
2.09
0.74
1.0
1.2
—
—
—
0
0
5
24
2.09
0.74
4.0
2.1
—
—
—
0
0
136
1216
1.15
0.72
4.5
4.6
1.01
1.02
kg/l
2.08
20
179
15
101
1.50
0.70
1.1
1.2
4.57
3.90
mmol/l
0.77
15
92
(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
5
27
1.86
0.68
1.2
1.2
—
—
—
0
0
9
59
1.53
0.68
2.4
1.4
—
—
—
0
0
9
59
1.53
0.68
2.4
1.4
—
—
—
0
0
58
488
1.21
0.65
3.9
3.9
1.21
1.23
mmol/l
1.50
52
422
483
4982
0.90
0.62
5.1
4.6
1.40
1.47
mmol/l
3.12
451
4496
0
20
0.00
0.60
0.0
1.6
—
64.48
—
0
20
0
21
0.00
0.60
0.0
1.4
—
—
—
0
0
85
747
1.16
0.59
2.3
1.8
—
—
—
0
0
15
106
1.42
0.58
1.3
1.2
—
—
—
0
0
6
36
1.67
0.56
2.0
1.6
0.67
3.89
u/field
—
6
25
11
73
1.52
0.56
1.9
1.6
—
—
—
0
0
129
1171
1.12
0.56
1.6
1.6
1.33
1.33
mg/l
0.01
101
924
15
107
1.41
0.55
1.4
1.2
—
—
—
0
0
467
4812
0.91
0.54
4.5
4.1
1.30
1.25
mmol/l
0.98
431
4305
489
5027
0.91
0.54
5.0
4.6
4.29
4.52
mmol/l
5.72
462
4567
21
160
1.32
0.54
1.8
1.6
—
—
—
0
0
9
61
1.48
0.54
2.0
1.6
—
—
—
0
0
11
74
1.49
0.53
1.9
1.6
—
—
—
0
0
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
27
214
1.27
0.53
2.6
2.4
0.42
0.38
u/ml
0.20
15
130
16
117
1.38
0.52
2.6
2.5
15.90
16.03
%
—
9
58
141
1530
0.90
0.50
4.7
4.6
21.29
21.06
%
0.07
73
764
499
4863
1.09
0.47
21.0
15.8
72.95
73.91
ml/min/173m2
0.40
418
4034
12
85
1.42
0.47
1.1
1.3
232.33
236.79
miu/ml
—
6
36
13
94
1.39
0.46
1.8
1.5
—
—
—
0
0
5
85
0.59
0.45
1.2
1.1
—
—
—
0
0
7
51
1.38
0.44
1.7
2.4
—
—
—
0
0
8
56
1.43
0.42
1.0
1.1
—
—
—
0
0
0
16
0.00
0.41
0.0
1.2
—
150.42
—
0
16
5
34
1.47
0.40
1.2
2.9
—
—
—
0
0
0
18
0.00
0.40
0.0
1.5
—
—
—
0
0
9
71
1.27
0.36
2.7
3.9
—
—
—
0
0
26
217
1.21
0.36
2.4
3.1
—
—
—
0
0
17
135
1.27
0.35
3.9
3.9
20.68
26.92
mg/l
0.58
11
86
6
44
1.37
0.34
2.2
2.1
—
—
—
0
0
6
47
1.28
0.32
1.7
1.7
—
—
—
0
0
508
5170
0.94
0.31
5.6
5.2
2.46
2.62
mmol/l
3.90
473
4669
30
259
1.17
0.30
4.8
6.3
1.57
1.55
%
0.05
30
244
12
93
1.30
0.30
1.7
1.8
56.00
47.09
nmol/l
0.53
12
85
182
1905
0.94
0.29
5.3
5.5
4.54
3.00
ug/l
0.51
166
1676
26
224
1.17
0.27
2.0
1.6
—
—
—
0
0
24
208
1.16
0.24
1.0
1.0
—
—
—
0
0
5
38
1.32
0.23
1.0
1.4
—
—
—
0
0
68
731
0.92
0.23
8.3
8.1
—
—
—
0
0
155
1486
1.06
0.22
4.8
4.4
0.00
0.00
estimate
-0.00
49
471
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
128
1222
1.06
0.21
3.7
3.2
2.49
2.46
mmol/l
2.04
113
1069
0
13
0.00
0.21
0.0
1.2
—
—
—
0
0
6
48
1.25
0.20
1.2
1.1
—
—
—
0
0
0
14
0.00
0.20
0.0
1.7
—
1.23
—
0
14
6
49
1.23
0.20
2.3
1.6
—
—
—
0
0
27
301
0.89
0.19
6.7
3.2
24.63
25.01
mmol/l
0.24
27
295
10
82
1.22
0.17
1.1
1.1
—
—
—
0
0
431
4370
0.96
0.17
27.4
19.8
16.67
15.38
%
3.28
425
4295
65
613
1.07
0.16
4.4
3.7
—
—
—
0
0
8
70
1.14
0.16
2.3
1.6
—
—
—
0
0
40
374
1.07
0.13
5.5
3.0
115.90
124.54
g/l
2.23
40
369
9
108
0.83
0.13
4.7
1.6
—
—
—
0
0
10
86
1.17
0.11
2.0
1.5
—
—
—
0
0
10
86
1.17
0.11
2.1
1.7
—
—
—
0
0
505
5088
0.97
0.10
5.5
4.9
6.22
6.04
mmol/l
1.64
461
4547
135
1382
0.97
0.09
1.7
1.6
1.25
1.31
mmol/l
0.52
119
1138
13
144
0.90
0.08
2.0
1.4
—
—
—
0
0
6
74
0.81
0.07
2.5
1.6
—
—
—
0
0
8
77
1.04
0.07
1.9
1.6
—
—
—
0
0
28
294
0.95
0.06
5.0
3.7
47.04
47.85
%
0.06
28
289
10
90
1.11
0.05
3.7
2.7
4.50
4.53
e9/l
—
10
90
107
1087
0.98
0.04
3.3
3.2
0.78
0.80
ug/l
0.11
83
759
205
2068
0.99
0.04
4.8
4.4
—
—
—
0
0
59
579
1.02
0.03
2.2
2.5
7.92
6.21
ug/l
0.35
40
493
57
581
0.98
0.03
4.3
3.2
378.47
247.82
ng/l
0.55
49
535
58
590
0.98
0.02
1.8
1.4
—
—
—
0
0
21
202
1.04
0.02
1.9
1.5
—
—
—
0
0
58
588
0.99
0.01
1.4
1.4
—
—
—
0
0
10
95
1.05
0.00
4.5
3.2
66.00
59.48
%
—
10
95
14
144
0.97
0.00
7.4
8.9
103.29
105.16
mmol/l
0.66
14
132
44
437
1.01
0.00
2.4
2.8
52.17
60.03
ml/min/173m2
0.77
24
183
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.5
—
—
—
0
0
6
59
1.02
-0.00
1.0
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
107.40
—
0
5
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.1
—
—
—
0
0
6
62
0.97
-0.00
1.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.5
—
—
—
0
0
0
8
0.00
-0.00
0.0
3.4
—
84.54
—
0
8
Mortality – FinRegistry
↥This endpoint is excluded (different definition than used in FinnGen).
Relationships between endpoints
↥Index endpoint: D3_VITAMIN_B12_DEFICIENCY_ANEMIA_DUE_TO_INTRINSIC_FACTOR_DEFICIENCY – Vitamin B12 deficiency anemia due to intrinsic factor deficiency
GWS hits: 1
This endpoint is excluded (different definition than used in FinnGen).