Pericarditis

I9_PERICARD

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 I30, I32*
  • Hospital discharge: ICD-9 420
  • Hospital discharge: ICD-8 420
  • Cause of death: ICD-10 I30, I32*
  • Cause of death: ICD-9 420
  • Cause of death: ICD-8 420

2 out of 7 registries used, show all original rules.

1405

4. Check minimum number of events

None

1405

5. Include endpoints

None

1405

6. Filter based on genotype QC (FinnGen only)

1405

Control definitions (FinnGen only)

Control exclude
I9_OTHHEART

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 11148 3965 7055
Only index persons 8429 2937 5492
Unadjusted period prevalence (%)
Whole population 0.17 0.11 0.20
Only index persons 0.17 0.11 0.21
Median age at first event (years)
Whole population 52.56 60.45 47.91
Only index persons 47.96 57.21 43.01

-FinnGen-

Key figures

All Female Male
Number of individuals 1405 520 885
Unadjusted period prevalence (%) 0.31 0.18 0.39
Median age at first event (years) 54.08 54.38 53.90

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
1250
Matched controls
12498
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
I30.9
ICD-10 Finland
Acute pericarditis, unspecified
+∞
323.0
647
*
I48
ICD-10 Finland
Atrial fibrillation and flutter
94.8
322.4
350
51
I50.9
ICD-10 Finland
Heart failure, unspecified
100.9
226.2
245
30
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
11.7
219.5
452
575
207
Kela drug reimbursment
Chronic arrhythmias
213.4
195.3
198
11
290
Kela drug reimbursment
Apixaban, dabigatran, edoxaban and rivaroxaban for the treatment of atrial fibrillation
272.6
186.1
186
8
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
8.5
176.0
441
752
351
Kela drug reimbursment
Apixaban, dabigatran, edoxaban and rivaroxaban for the treatment of atrial fibrillation
+∞
175.2
164
*
I31.9
ICD-10 Finland
Disease of pericardium, unspecified
+∞
171.9
161
*
B01AA03
ATC
warfarin; systemic
9.1
152.5
355
521
I30.0
ICD-10 Finland
Acute nonspecific idiopathic pericarditis
+∞
151.2
142
*
C03CA01
ATC
furosemide; systemic
5.3
128.5
482
1316
C07AB07
ATC
bisoprolol; oral
4.3
122.2
682
2751
4209X
ICD-9 Finland
Acute pericarditis, Other and unspecified acute pericarditis[PERICARDITIS ALIA DEFINITA SEU NUD]
+∞
110.0
104
*
I30.8
ICD-10 Finland
Other forms of acute pericarditis
+∞
107.9
102
*
GD1AA
NOMESCO Finland
Thorax X-ray examination
3.8
105.8
690
3058
FN1AC
NOMESCO Finland
Angiography of heart and/or coronary arteries
5.1
104.4
390
1020
I50.0
ICD-10 Finland
Congestive heart failure
111.7
103.9
112
11
XFP20
NOMESCO Finland
Check up of cardiac pacemaker
186.8
99.9
103
6
I30.1
ICD-10 Finland
Infective pericarditis
+∞
98.2
93
*
TFP20
NOMESCO Finland
Cardiodefibrillation
87.2
93.7
104
13
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
5.3
91.9
319
755
Z95.0
ICD-10 Finland
Presence of electronic cardiac devices
203.0
91.6
94
5
I35.0
ICD-10 Finland
Aortic (valve) stenosis
65.8
89.3
103
17
R07.4
ICD-10 Finland
Chest pain, unspecified
3.8
86.4
470
1708
B01AF02
ATC
apixaban; oral
17.3
83.5
135
87
I50.1
ICD-10 Finland
Left ventricular failure
418.0
79.8
79
*
I35.1
ICD-10 Finland
Aortic (valve) insufficiency
73.5
78.5
89
13
FM1BE
NOMESCO Finland
Cardiac ultrasound examination through oesophagus
11.1
76.9
152
154
XF400
NOMESCO Finland
ECG with 12 standard connections
4.2
72.5
321
950
I40.9
ICD-10 Finland
Acute myocarditis, unspecified
738.8
71.9
70
*
I48.0
ICD-10 Finland
Paroxysmal atrial fibrillation
157.1
70.8
74
5
XF404
NOMESCO Finland
Ambulatory ECG
9.7
69.9
148
170
I34.09
ICD-10 Finland
Mitral (valve) insufficiency
187.9
68.8
71
*
R06.0
ICD-10 Finland
Dyspnoea
3.6
68.4
372
1307
Z45.0
ICD-10 Finland
Adjustment and management of cardiac devices
243.1
67.9
69
*
C01AA05
ATC
digoxin; systemic
14.2
67.6
118
91
H02AB06
ATC
prednisolone; systemic
2.8
66.5
674
3642
J18.9
ICD-10 Finland
Pneumonia, unspecified
3.3
66.1
418
1641
I25.1
ICD-10 Finland
Atherosclerotic heart disease
3.6
64.4
351
1225
A49.9
ICD-10 Finland
Bacterial infection, unspecified
4.8
60.9
225
548
42009
ICD-8 Finland
Acute pericarditis, nonrheumatic, Unspecified
+∞
59.9
57
*
R50.9
ICD-10 Finland
Fever, unspecified
3.9
57.8
270
820
I48.9
ICD-10 Finland
Atrial fibrillation and atrial flutter, unspecified
305.6
57.8
58
*
FM1DE
NOMESCO Finland
Doppler ultrasound examination of heart
7.3
56.9
144
219
I51.4
ICD-10 Finland
Myocarditis, unspecified
+∞
56.7
54
*
J90
ICD-10 Finland
Pleural effusion, not elsewhere classified
10.0
55.7
115
125
FEB10
NOMESCO Finland
Decompression and drainage of pericardium
294.1
55.7
56
*
I34.00
ICD-10 Finland
Mitral (valve) incompetence NOS or of specified cause, except rheumatic
+∞
55.6
53
*
C03DA01
ATC
spironolactone; oral
5.7
54.7
168
330
K78
ICPC
Atrial fibrillation/flutter
19.7
54.3
83
45
I34.1
ICD-10 Finland
Mitral (valve) prolapse
103.1
54.3
59
6
FPE20
NOMESCO Finland
Implantation of transvenous cardiac pacemaker with atrial and ventricular electrodes
550.6
53.9
53
*
Z95.2
ICD-10 Finland
Presence of prosthetic heart valve
277.0
52.5
53
*
I49.5
ICD-10 Finland
Sick sinus syndrome
271.4
51.5
52
*
A02BC02
ATC
pantoprazole; systemic
2.5
50.9
836
5569
AN1
HP
Coronary angiography
4.4
48.9
193
496
FB1BD
NOMESCO Finland
Extensive CT examination of arteria pulmonalis
5.3
48.5
158
331
201
Kela drug reimbursment
Chronic cardiac insufficiency
12.7
48.4
88
74
I44.2
ICD-10 Finland
Atrioventricular block, complete
+∞
48.2
46
*
TPH04
NOMESCO Finland
Cathetrisation of vein
3.1
47.5
319
1258
GA4YT
NOMESCO Finland
Puncture of pleura with ultrasound guidance
12.7
47.4
86
72
C01DA08
ATC
isosorbide dinitrate; oral, oral aerosol, sublingual, transdermal
3.0
47.0
335
1374
I49.9
ICD-10 Finland
Cardiac arrhythmia, unspecified
6.5
46.6
128
217
WX892
NOMESCO Finland
Monitored bed care
5.4
46.5
149
306
ZXD05
NOMESCO Finland
Urgent procedure
2.6
46.1
437
2133
I47.1
ICD-10 Finland
Supraventricular tachycardia
85.0
44.2
49
6
C01BD01
ATC
amiodarone; systemic
121.9
44.0
47
*
FXA00
NOMESCO Finland
Total cardiopulmonary bypass in normothermia or moderate hypothermia at concurrent surgical procedure
10.5
43.7
87
88
42007
ICD-8 Finland
Acute pericarditis, nonrheumatic, Suspecta
+∞
43.0
41
*
L04AX01
ATC
azathioprine; systemic
6.9
42.9
111
173
I31.3
ICD-10 Finland
Pericardial effusion (noninflammatory)
+∞
40.8
39
*
J15.9
ICD-10 Finland
Bacterial pneumonia, unspecified
4.1
39.8
169
461
206
Kela drug reimbursment
Chronic coronary artery disease and dyslipidaemia associated with chronic coronary artery disease
2.8
37.0
274
1133
FM1DG
NOMESCO Finland
Very extensive MRI examination of heart with high intesity magnet
82.6
36.0
40
5
I35.2
ICD-10 Finland
Aortic (valve) stenosis with insufficiency
82.6
36.0
40
5
I49.3
ICD-10 Finland
Ventricular premature depolarization
10.5
35.9
71
71
J01MA12
ATC
levofloxacin; systemic
2.7
35.5
288
1254
C07AB02
ATC
metoprolol; systemic
2.7
35.3
276
1176
I97.0
ICD-10 Finland
Postcardiotomy syndrome
97.9
34.9
38
*
4273A
ICD-9 Finland
Cardiac dysrhythmias, Atrial fibrillation and flutter
+∞
34.5
33
*
C01BC04
ATC
flecainide; systemic
78.4
34.0
38
5
FPE00
NOMESCO Finland
Implantation of transvenous cardiac pacemaker with ventricular electrode
+∞
33.5
32
*
I42.0
ICD-10 Finland
Dilated cardiomyopathy
+∞
33.5
32
*
H02AB07
ATC
prednisone; oral
2.9
33.1
228
894
TFC00
NOMESCO Finland
Catheterisation of right atrium or ventricle
63.4
32.2
37
6
I42.9
ICD-10 Finland
Cardiomyopathy, unspecified
324.9
32.0
32
*
I20.09
ICD-10 Finland
Unstable angina
5.2
31.6
102
210
I31.8
ICD-10 Finland
Other specified diseases of pericardium
+∞
31.4
30
*
FMD10
NOMESCO Finland
Replacement of aortic valve using biological prosthesis
+∞
31.4
30
*
TFP34
NOMESCO Finland
Electrophysiological investigation
320.4
31.0
31
*
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
4.9
30.9
106
233
C01DA14
ATC
isosorbide mononitrate; oral
2.8
30.5
213
840
XF402
NOMESCO Finland
ECG with work load test
3.4
29.8
153
486
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
2.9
29.7
205
801
PD5BD
NOMESCO Finland
Extensive CT of aorta
12.2
29.6
54
46
I48.1
ICD-10 Finland
Persistent atrial fibrillation
+∞
29.3
28
*
R4110
NOMESCO Finland
Physiotherapy
2.3
29.3
348
1826
81
HP
Angiography of the heart and coronary arteries
4.3
29.1
113
282
I47.2
ICD-10 Finland
Ventricular tachycardia
105.9
28.8
31
*
B01AB05
ATC
enoxaparin; parenteral
2.2
28.7
371
2020
Z95.1
ICD-10 Finland
Presence of aortocoronary bypass graft
6.2
28.4
78
132
ZXE00
NOMESCO Finland
One hour or less
2.0
27.9
481
2946
WX872
NOMESCO Finland
Intensive care
5.4
27.8
86
168
C09AA05
ATC
ramipril; oral
2.3
27.4
305
1545
4209A
ICD-9 Finland
Acute pericarditis, Other and unspecified acute pericarditis[PERICARDITIS ACUTA INFECTIOSA]
+∞
27.2
26
*
M32.9
ICD-10 Finland
Systemic lupus erythematosus, unspecified
22.3
27.1
39
18
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
2.1
26.7
380
2145
P01BA02
ATC
hydroxychloroquine; oral
3.4
26.4
137
437
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
3.5
26.4
129
393
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
2.5
26.1
233
1052
C07AA07
ATC
sotalol; systemic
8.4
26.1
58
72
Z03.5
ICD-10 Finland
Observation for other suspected cardiovascular diseases
3.8
25.7
113
315
GD1DD
NOMESCO Finland
High resolution CT examination of lungs
4.6
25.5
92
213
I20.81
ICD-10 Finland
Other angina pectoris stenosed coronary artery
3.6
25.1
120
359
Z2221
NOMESCO Finland
Medical doctor
2.1
25.0
336
1839
I25.9
ICD-10 Finland
Chronic ischaemic heart disease, unspecified
3.2
24.5
138
467
202
Kela drug reimbursment
Connective tissue diseases, rheumatoid arthritis and comparable disease
2.8
24.1
170
667
GD1AD
NOMESCO Finland
Thorax CT examination
4.9
24.1
81
174
FKB10
NOMESCO Finland
Annuloplasty of mitral valve for insufficiency using ring
+∞
24.0
23
*
I36.1
ICD-10 Finland
Nonrheumatic tricuspid (valve) insufficiency
+∞
24.0
23
*
XFE00
NOMESCO Finland
Epicardial ultrasonography
10.8
23.9
46
44
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
2.1
23.9
344
1936
J01FF01
ATC
clindamycin; systemic
2.1
23.8
335
1864
FN1BC
NOMESCO Finland
Extensive angiography of hear and/or coronary arteries
5.0
23.8
78
163
L04AA06
ATC
mycophenolic acid; systemic
8.5
23.3
51
62
J01MA14
ATC
moxifloxacin; systemic
3.0
23.0
140
500
C01DA02
ATC
glyceryl trinitrate; oral, oral aerosol, sublingual, transdermal
2.2
22.9
258
1301
GD1BD
NOMESCO Finland
Thorax extensive CT-examination
3.8
22.8
99
273
ZXE10
NOMESCO Finland
More than one and less than three hours
1.9
22.5
432
2704
I33.0
ICD-10 Finland
Acute and subacute infective endocarditis
+∞
21.9
21
*
I32.8*M05.3
ICD-10 Finland
Pericarditis (in) rheumatoid
+∞
21.9
21
*
I44.1
ICD-10 Finland
Atrioventricular block, second degree
117.0
21.6
23
*
I11.0
ICD-10 Finland
Hypertensive heart disease with (congestive) heart failure
117.0
21.6
23
*
TPH07
NOMESCO Finland
Cathetrisation of artery
2.8
21.4
144
548
N02BE01
ATC
paracetamol; systemic, rectal
1.9
21.2
993
8313
I25.2
ICD-10 Finland
Old myocardial infarction
3.6
21.1
100
297
I20.99
ICD-10 Finland
Angina pectoris, unspecified
3.8
21.0
93
261
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.8
21.0
586
4138
123
Kela drug reimbursment
Chronic disorders of vitamin D metabolism
7.9
20.9
48
63
FMD00
NOMESCO Finland
Replacement of aortic valve using mechanical prosthesis
+∞
20.9
20
*
N02AX02
ATC
tramadol; systemic, rectal
1.8
20.8
513
3472
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
2.4
20.8
186
834
I71.2
ICD-10 Finland
Thoracic aortic aneurysm, without mention of rupture
8.0
20.4
46
59
XF640
NOMESCO Finland
NA
9.2
20.2
42
47
WX408
NOMESCO Finland
General anesthesy, balanced
2.0
20.0
323
1881
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
2.4
20.0
195
910
R07.3
ICD-10 Finland
Other chest pain
2.9
19.9
129
480
M04AA01
ATC
allopurinol; systemic
2.5
19.9
170
743
TK800
NOMESCO Finland
Hemodialysis
7.5
19.9
47
65
I48.2
ICD-10 Finland
Chronic atrial fibrillation
+∞
19.8
19
*
42000
ICD-8 Finland
Acute pericarditis, nonrheumatic, Pleuropericarditis
+∞
19.8
19
*
FPE30
NOMESCO Finland
Replacement of transvenous cardiac pacemaker pulse generator
106.7
19.6
21
*
C08DA01
ATC
verapamil; systemic
6.4
19.4
51
82
J01FA06
ATC
roxithromycin; oral
1.8
19.3
459
3054
A02BC01
ATC
omeprazole; systemic
1.9
19.1
343
2069
I50
ICD-10 Finland
Heart failure
14.2
19.1
32
23
138
Kela drug reimbursment
Severe anaemia associated with chronic renal failure
7.5
19.1
45
62
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
1.8
19.0
454
3019
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.8
18.9
385
2428
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
4.0
18.9
78
206
127
Kela drug reimbursment
Transplant complication
8.2
18.8
42
53
I49.0
ICD-10 Finland
Ventricular fibrillation and flutter
+∞
18.8
18
*
I10
ICD-10 Finland
Essential (primary) hypertension
1.7
18.4
654
4894
TGC00
NOMESCO Finland
Bronchial lavation
5.9
18.3
51
89
J01DB01
ATC
cefalexin; oral
1.8
18.3
939
7837
AS4
HP
Physiological pacemaker insertion DDD (R)
+∞
17.7
17
*
J01CA04
ATC
amoxicillin; systemic
1.8
17.7
913
7578
FNA01
NOMESCO Finland
Anastomosis to coronary artery from internal mammary artery, one distal anastamosis
3.8
17.5
75
205
Z3226
NOMESCO Finland
Physiotherapist
2.1
17.5
225
1187
N18.9
ICD-10 Finland
Chronic kidney disease, unspecified
3.7
17.1
77
220
R04.0
ICD-10 Finland
Epistaxis
3.2
17.0
90
292
TFB00
NOMESCO Finland
Cathetrisation of pulmonal artery
11.3
16.8
31
28
TFP35
NOMESCO Finland
Electroanatomical mapping
+∞
16.7
16
*
I32.8*M32.1
ICD-10 Finland
Pericarditis (in) systemic lupus erythematosus
+∞
16.7
16
*
AA1AD
NOMESCO Finland
CT of head and brain
2.0
16.7
259
1473
K83
ICPC
Heart valve disease NOS
91.3
16.6
18
*
A46
ICD-10 Finland
Erysipelas
2.3
16.5
168
796
Z49.1
ICD-10 Finland
Extracorporeal dialysis
10.9
16.5
31
29
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
2.7
16.5
119
471
R03AC02
ATC
salbutamol; inhalant
1.7
16.5
562
4109
NK6QA
NOMESCO Finland
Measurement of bone density from tow or more locations with X-ray
3.3
16.4
84
266
Z3231
NOMESCO Finland
Registered nurse
1.8
16.2
324
2011
ZXD10
NOMESCO Finland
Scheduled procedure
1.7
16.1
433
2951
I21.49
ICD-10 Finland
Acute subendocardial infarction unspecified coronary artery status
3.5
16.0
75
222
R02
ICPC
Shortness of breath/dyspnoea
2.5
15.9
131
559
A41.9
ICD-10 Finland
Sepsis, unspecified
4.3
15.9
59
142
I20.90
ICD-10 Finland
Angina pectoris, unspecified
4.2
15.9
60
147
K84
ICPC
Heart disease other
8.5
15.8
34
41
SPAT1253
SPAT
Initiation, adjustment, discontinuation or repetition of medication
1.8
15.8
327
2055
ZXE20
NOMESCO Finland
More than three and less than five hours
2.2
15.7
172
845
C10AX09
ATC
ezetimibe; oral
2.4
15.7
139
618
AB2
HP
AVR bio, stent
+∞
15.7
15
*
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.7
15.6
445
3076
SPAT1097
SPAT
Recording of ECG
2.2
15.4
170
839
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.7
15.4
497
3559
NK4XE
NOMESCO Finland
Joint ultrasound examination not elsewhere classified
2.9
15.3
93
332
C10AA05
ATC
atorvastatin; oral
1.7
15.1
424
2911
61
HP
Catheterization and pressure measurement of the left side of the heart
6.5
15.1
39
62
WX404
NOMESCO Finland
Intravenous generell anesthesy
2.0
14.8
217
1204
Z2446
NOMESCO Finland
Social worker
2.9
14.7
93
339
UGC12
NOMESCO Finland
Flexible bronchoscopy
2.6
14.6
109
441
AQ1
HP
Conventional electrophysiological examination
+∞
14.6
14
*
TFP44
NOMESCO Finland
Ablation treatment of typical atrial flutter
+∞
14.6
14
*
A12AA04
ATC
calcium carbonate; oral
8.6
14.5
31
37
I25.0
ICD-10 Finland
Atherosclerotic cardiovascular disease, so described
3.4
14.5
72
223
L04AX03
ATC
methotrexate; systemic (immunosuppressants)
2.5
14.5
122
526
SPAT1148
SPAT
Treatment of chronic ulcer or burn
2.2
14.4
161
796
A11
ICPC
Chest pain NOS
2.9
14.4
92
338
ZX120
NOMESCO Finland
Intravenous
2.5
14.4
116
489
A02BC05
ATC
esomeprazole; systemic
1.7
14.3
439
3082
PH1AC
NOMESCO Finland
Flebography of over extremity with X-ray
43.0
14.1
17
*
A11CC03
ATC
alfacalcidol; systemic
6.0
14.0
38
65
205
Kela drug reimbursment
Chronic hypertension
1.7
13.9
320
2064
R00.2
ICD-10 Finland
Palpitations
3.2
13.8
73
237
D64.9
ICD-10 Finland
Anaemia, unspecified
2.4
13.8
118
511
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
2.3
13.8
131
599
I34.0
ICD-10 Finland
Mitral (valve) insufficiency
24.1
13.8
19
8
B01AC04
ATC
clopidogrel; oral
2.0
13.6
178
944
FE1AT
NOMESCO Finland
Pericardial puncture with ultrasound guidance
+∞
13.6
13
*
42008
ICD-8 Finland
Acute pericarditis, nonrheumatic, Alii definiti
+∞
13.6
13
*
TFP46
NOMESCO Finland
Ablation treatment of atrial fibrillation
+∞
13.6
13
*
342
Kela drug reimbursment
Dronedarone
+∞
13.6
13
*
FE2AT
NOMESCO Finland
Pericardial cathetrisation with ultrasound guidance
+∞
13.6
13
*
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
2.0
13.5
183
981
I20.00
ICD-10 Finland
Unstable angina
4.4
13.4
48
112
A12BA01
ATC
potassium chloride; oral
3.9
13.4
55
146
E11.9
ICD-10 Finland
Type 2 diabetes mellitus, without complications
1.8
13.3
262
1604
P01AB01
ATC
metronidazole; oral, rectal
1.6
13.1
414
2909
M05.8
ICD-10 Finland
Other seropositive rheumatoid arthritis
2.9
13.1
80
286
B01AE07
ATC
dabigatran etexilate; oral
5.3
13.1
39
75
WX002
NOMESCO Finland
Sedation and analgesia
1.9
13.1
221
1288
GAA10
NOMESCO Finland
Intercostal insertion of pleural drainage tube
5.8
13.0
36
63
R00.0
ICD-10 Finland
Tachycardia, unspecified
4.1
13.0
50
125
E11.8
ICD-10 Finland
Type 2 diabetes mellitus, with unspecified complications
2.5
13.0
107
455
WZB00
NOMESCO Finland
Telephone receipt or other advice
1.7
12.9
292
1868
G47.3
ICD-10 Finland
Sleep apnoea
1.8
12.9
241
1449
WX402
NOMESCO Finland
General anaesthesia
2.0
12.9
182
990
TFP00
NOMESCO Finland
Temporary use of transvenous or epicardial pacemaker
50.5
12.9
15
*
Z94.0
ICD-10 Finland
Kidney transplant status
8.2
12.8
28
35
N18.8
ICD-10 Finland
Other chronic renal failure
4.9
12.7
41
86
T81.0
ICD-10 Finland
Haemorrhage and haematoma complicating a procedure, not elsewhere classified
2.8
12.7
80
293
N02AJ06
ATC
codeine and paracetamol; systemic
1.6
12.7
388
2701
XF600
NOMESCO Finland
Bloodpressure measurement
2.8
12.7
83
311
C08CA01
ATC
amlodipine; oral
1.6
12.6
391
2731
TFP30
NOMESCO Finland
Cathetric examination for cardiac arrythmia
70.6
12.6
14
*
B03XA02
ATC
darbepoetin alfa; parenteral
6.0
12.6
34
58
Y83
ICD-10 Finland
Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
2.6
12.6
93
375
190
Kela drug reimbursment
Lanthanum carbonate, sevelamer and sucroferric oxyhydroxide
11.1
12.5
23
21
I48.3
ICD-10 Finland
Typical atrial flutter
+∞
12.5
12
*
C01BD07
ATC
dronedarone; oral
+∞
12.5
12
*
AC4
HP
MVP
+∞
12.5
12
*
FKC50
NOMESCO Finland
Repair of mitral valve for insufficiency using prosthetic chord
+∞
12.5
12
*
WZC00
NOMESCO Finland
Planning of intervention or health care consultation
1.6
12.5
358
2448
J01DA01
ATC
[U] cefalexin; systemic
1.5
12.5
700
5646
R91
ICD-10 Finland
Abnormal findings on diagnostic imaging of lung
2.2
12.4
127
604
I21.99
ICD-10 Finland
Myocardial infarction (acute) UNS unspecified coronary artery status
4.7
12.4
41
89
L04AD01
ATC
ciclosporin; systemic
5.1
12.4
38
76
N02AA05
ATC
oxycodone; systemic
2.0
12.3
176
960
R42
ICD-10 Finland
Dizziness and giddiness
1.8
12.3
225
1342
E78.5
ICD-10 Finland
Hyperlipidaemia, unspecified
2.3
12.1
115
526
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
2.4
12.1
108
482
N17.9
ICD-10 Finland
Acute renal failure, unspecified
3.9
12.0
49
130
GD2SN
NOMESCO Finland
Lung ventilation SPECT
21.5
12.0
17
8
UJF32
NOMESCO Finland
Coloscopy
1.7
11.8
270
1726
Z04.8
ICD-10 Finland
Examination and observation for other specified reasons
2.1
11.7
130
642
TPH20
NOMESCO Finland
Insertion of central venous catheter through subclavian or brachiocephalic vein
4.4
11.7
42
99
TNX10
NOMESCO Finland
Arthrocentesis, unspecified region, unspecified region
2.6
11.6
85
341
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
2.2
11.6
117
551
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
2.3
11.6
114
530
J01AA02
ATC
doxycycline; systemic
1.6
11.6
871
7451
J45.9
ICD-10 Finland
Asthma, unspecified
1.9
11.6
183
1037
I25.5
ICD-10 Finland
Ischaemic cardiomyopathy
11.2
11.6
21
19
J01MA02
ATC
ciprofloxacin; systemic
1.6
11.5
437
3195
103
Kela drug reimbursment
Diabetes, insulin-treated
1.7
11.5
301
1999
I15.1
ICD-10 Finland
Hypertension secondary to other renal disorders
9.3
11.5
23
25
73
HP
Initial pacemaker installation
+∞
11.5
11
*
72
HP
Catheter ablation of arrhythmia
+∞
11.5
11
*
I46.0
ICD-10 Finland
Cardiac arrest with successful resuscitation
+∞
11.5
11
*
42798
ICD-8 Finland
Symptomatic heart disease, Alia arrhytmia definita
+∞
11.5
11
*
289
Kela drug reimbursment
Combination product containing sacubitril and valsartan
+∞
11.5
11
*
AS2
HP
Ventricular pacemaker insertion VVI (R)
+∞
11.5
11
*
I32.8
ICD-10 Finland
Pericarditis in other diseases classified elsewhere
+∞
11.5
11
*
I63.4
ICD-10 Finland
Cerebral infarction due to embolism of cerebral arteries
7.0
11.4
27
39
GD1ED
NOMESCO Finland
Extensive high resolution CT examination of lungs
3.7
11.3
48
132
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
2.1
11.3
135
688
XF409
NOMESCO Finland
Other special ECG
35.3
11.3
14
*
I11.9
ICD-10 Finland
Hypertensive heart disease without (congestive) heart failure
3.9
11.1
45
119
R53
ICD-10 Finland
Malaise and fatigue
1.8
11.1
205
1225
TPH90
NOMESCO Finland
Removal of fixed intravenous catheter
6.5
11.1
28
44
N05CF01
ATC
zopiclone; oral
1.6
11.1
352
2461
R00.1
ICD-10 Finland
Bradycardia, unspecified
5.6
11.1
31
56
A41.0
ICD-10 Finland
Sepsis due to Staphylococcus aureus
5.6
11.1
31
56
K80
ICPC
Cardiac arrhythmia NOS
3.0
11.0
63
217
L01BA01
ATC
methotrexate; systemic (folic acid analog.)
3.1
10.9
59
196
C09CA01
ATC
losartan; oral
1.7
10.9
259
1673
SPAT1263
SPAT
Sampling
1.5
10.8
427
3141
J86.9
ICD-10 Finland
Pyothorax without fistula
10.7
10.8
20
19
GD1UN
NOMESCO Finland
Lung circulation SPECT
18.0
10.7
16
9
WW200
NOMESCO Finland
Immunization
4.2
10.7
39
94
PG1DE
NOMESCO Finland
Other extensive ultrasound examination of artery
3.1
10.7
58
194
SPAT1254
SPAT
Administration of medicine
1.9
10.7
156
860
I35.9
ICD-10 Finland
Aortic valve disorder, unspecified
60.5
10.6
12
*
I42.2
ICD-10 Finland
Other hypertrophic cardiomyopathy
60.5
10.6
12
*
FNC10
NOMESCO Finland
Aorto-coronary venous bypass with single distal anastomosis
6.6
10.5
26
40
I40.0
ICD-10 Finland
Infective myocarditis
+∞
10.4
10
*
42792
ICD-8 Finland
Symptomatic heart disease, Fibrillatio auricularis
+∞
10.4
10
*
I31.1
ICD-10 Finland
Chronic constrictive pericarditis
+∞
10.4
10
*
I21.41
ICD-10 Finland
Acute subendocardial infarction stenosed coronary artery
3.1
10.4
55
181
137
Kela drug reimbursment
Uraemia requiring dialysis
8.3
10.3
22
27
N18.0
ICD-10 Finland
End-stage renal disease
8.3
10.3
22
27
R07.1
ICD-10 Finland
Chest pain on breathing
5.6
10.3
29
53
K99
ICPC
Cardiovascular disease other
5.1
10.2
31
62
I49.4
ICD-10 Finland
Other and unspecified premature depolarization
6.3
10.2
26
42
ZXA05
NOMESCO Finland
Left side
1.6
10.2
276
1844
A02BC03
ATC
lansoprazole; oral
1.6
10.1
309
2129
JN4BD
NOMESCO Finland
Extensive body CT
2.0
10.1
140
753
Z01.8
ICD-10 Finland
Other specified special examinations
1.7
10.1
221
1388
ZXE02
NOMESCO Finland
Procedure duration 10 to 19 minutes
2.9
10.0
62
223
M05BA04
ATC
alendronic acid; oral
2.3
10.0
92
418
E11.7
ICD-10 Finland
Type 2 diabetes mellitus, with multiple complications
3.0
9.9
57
198
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
1.8
9.9
196
1198
I20.01
ICD-10 Finland
Unstable angina
4.0
9.9
38
97
I63.9
ICD-10 Finland
Cerebral infarction, unspecified
2.1
9.8
114
575
7865A
ICD-9 Finland
Symptoms involving respiratory system and other chest symptoms, Chest pain
4.6
9.8
33
74
R60.0
ICD-10 Finland
Localized oedema
2.1
9.7
111
555
J94.8
ICD-10 Finland
Other specified pleural conditions
5.4
9.7
28
53
R05
ICD-10 Finland
Cough
1.7
9.7
197
1211
KAS10
NOMESCO Finland
Allogenic transplantation of kidney from cadaver donor
7.9
9.6
21
27
H02AB04
ATC
methylprednisolone; systemic
1.9
9.6
155
884
TK810
NOMESCO Finland
Hemofiltration
11.5
9.6
17
15
R03AK06
ATC
salmeterol and fluticasone; inhalant
1.9
9.5
145
808
SPAT1301
SPAT
No procedures
1.6
9.5
323
2279
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
1.8
9.5
180
1082
N03AX16
ATC
pregabalin; oral
1.7
9.5
240
1569
I20.89
ICD-10 Finland
Other angina pectoris unspecified coronary artery status
3.1
9.4
51
171
S97
ICPC
Chronic ulcer skin
2.8
9.4
59
216
B01AF01
ATC
rivaroxaban; oral
2.2
9.4
97
462
V03AE02
ATC
sevelamer; oral
17.7
9.4
14
8
I70.2
ICD-10 Finland
Atherosclerosis of arteries of extremities
2.1
9.4
102
499
C09DX04
ATC
valsartan and sacubitril; oral
+∞
9.4
9
*
381
Kela drug reimbursment
Combination product containing sacubitril and valsartan
+∞
9.4
9
*
I32.8*N18.8
ICD-10 Finland
Pericarditis (in) uraemic
+∞
9.4
9
*
TFC25
NOMESCO Finland
Transseptal catheterisation of left atrium or ventricle
+∞
9.4
9
*
I42.8
ICD-10 Finland
Other cardiomyopathies
+∞
9.4
9
*
FME20
NOMESCO Finland
Transvenous aortic valve replacement via femoral artery
+∞
9.4
9
*
42700
ICD-8 Finland
Symptomatic heart disease, Congestive heart failure
+∞
9.4
9
*
I32.0
ICD-10 Finland
Pericarditis in bacterial diseases classified elsewhere
+∞
9.4
9
*
XF655
NOMESCO Finland
Measurement of heart muscle perfusion with exercise
4.1
9.4
35
87
JN4AD
NOMESCO Finland
Body CT examination
2.2
9.4
93
438
FL1AC
NOMESCO Finland
Left cardioangiography
5.9
9.4
25
43
L03.1
ICD-10 Finland
Cellulitis of other parts of limb
4.0
9.4
36
92
FC1AC
NOMESCO Finland
Angiography of thoracal aortta
21.9
9.4
13
6
ZXE40
NOMESCO Finland
More than seven and less than nine hours
4.3
9.3
33
78
M10.9
ICD-10 Finland
Gout, unspecified
2.5
9.3
70
287
I49.1
ICD-10 Finland
Atrial premature depolarization
6.5
9.3
23
36
L04AD02
ATC
tacrolimus; systemic (calcineurin inhibitors)
7.3
9.2
21
29
GA1AE
NOMESCO Finland
Ultrasound examination of thorax
4.3
9.2
33
79
ZXE30
NOMESCO Finland
More than five and less than seven hours
2.7
9.2
62
238
UJF45
NOMESCO Finland
Flexible sigmoidoscopy with biopsy
2.2
9.2
93
440
A10AC01
ATC
insulin (human); parenteral (insulins and analog. for injection, intermediate-acting)
2.2
9.2
93
440
M35.9
ICD-10 Finland
Systemic involvement of connective tissue, unspecified
6.8
9.1
22
33
R10.1
ICD-10 Finland
Pain localized to upper abdomen
1.8
9.1
161
945
A10AE04
ATC
insulin glargine; parenteral
2.1
9.1
107
542
FN1YT
NOMESCO Finland
Percutaneous insertion of coronary artery stent
2.7
9.1
61
232
B05DB
ATC
Hypertonic solutions
11.6
9.1
16
14
N05BA04
ATC
oxazepam; oral
1.6
9.0
248
1660
11
HP
Coronary artery bypass surgery
3.8
9.0
36
96
I71.9
ICD-10 Finland
Aortic aneurysm of unspecified site, without mention of rupture
7.5
8.9
20
27
FM1CG
NOMESCO Finland
Extensive examination of hear with high intensity magnet
18.7
8.9
13
7
Q23.11
ICD-10 Finland
Bicuspid aortic valve
18.7
8.9
13
7
B99
ICD-10 Finland
Other and unspecified infectious diseases
4.7
8.9
29
63
ZXE03
NOMESCO Finland
Procedure duration 20 to 29 minutes
2.4
8.9
71
301
203
Kela drug reimbursment
Chronic asthma and similar chronic obstructive pulmonary diseases
1.7
8.9
198
1251
L04AA13
ATC
leflunomide; oral
3.6
8.9
38
107
I47.9
ICD-10 Finland
Paroxysmal tachycardia, unspecified
12.6
8.9
15
12
215
Kela drug reimbursment
Diabetes, non-insulin-treated
1.6
8.8
256
1735
R03BB04
ATC
tiotropium bromide; inhalant
2.0
8.8
106
541
213
Kela drug reimbursment
Fat metabolism disorder associated with chronic coronary artery disease
2.2
8.7
83
383
62
HP
Catheterization and pressure measurement of the right side of the heart
50.3
8.7
10
*
FM1BD
NOMESCO Finland
Extensive CT of heart
50.3
8.7
10
*
FN1CC
NOMESCO Finland
Very extensive angiography of heart and/or coronary arteries
5.8
8.6
23
40
X59
ICD-10 Finland
Exposure to unspecified factor
1.7
8.6
192
1211
320
Kela drug reimbursment
Lanthanum carbonate, sevelamer and sucroferric oxyhydroxide
11.7
8.6
15
13
I21.90
ICD-10 Finland
Myocardial infarction (acute) UNS no detected stenosis of the coronary artery
4.8
8.6
27
57
G45.1
ICD-10 Finland
Carotid artery syndrome (hemispheric)
3.2
8.6
44
143
GD1LA
NOMESCO Finland
GD
16.4
8.6
13
8
A10AB05
ATC
insulin aspart; parenteral (insulins and analog. for injection, fast-acting)
2.1
8.5
91
441
L97
ICD-10 Finland
Ulcer of lower limb, not elsewhere classified
3.4
8.5
40
122
FWD00
NOMESCO Finland
Reoperation for superficial haemorrhage in surgery of heart and major thoracic vessels
20.2
8.5
12
6
C09AA02
ATC
enalapril; systemic
1.6
8.4
213
1392
7100A
ICD-9 Finland
Diffuse diseases of connective tissue, Systemic lupus erythematosus
90.6
8.4
9
*
I34.9
ICD-10 Finland
Nonrheumatic mitral valve disorder, unspecified
90.6
8.4
9
*
C01BA01
ATC
quinidine; oral
90.6
8.4
9
*
PD4BC
NOMESCO Finland
Extensive arterigography of lower extremity with X-ray
4.9
8.4
26
54
FN2BA
NOMESCO Finland
Percutaneous transluminal coronary angioplasty with stent (includes balloon pre-dilation)
2.5
8.4
62
253
SPAT1104
SPAT
Monitoring of emergency patient
2.4
8.4
70
303
T90
ICPC
Diabetes non-insulin dependent
1.6
8.4
237
1594
AB1
HP
AVR mechanical
+∞
8.3
8
*
FCA70
NOMESCO Finland
Resection of aortic root and ascending aorta with reimplantation of coronary arteries and use of biological valve prosthesis and tube graft
+∞
8.3
8
*
TFJ02
NOMESCO Finland
Muscle biopsy of heart
+∞
8.3
8
*
FKC20
NOMESCO Finland
Plastic repair of mitral valve leaflet for insufficiency
+∞
8.3
8
*
I44.3
ICD-10 Finland
Other and unspecified atrioventricular block
+∞
8.3
8
*
TFC20
NOMESCO Finland
Catheterisation of both sides of heart
+∞
8.3
8
*
TFP40
NOMESCO Finland
Ablation treatment for a-v node re-entry activation
+∞
8.3
8
*
FEA00
NOMESCO Finland
Closed external drainage of pericardium
+∞
8.3
8
*
42299
ICD-8 Finland
Acute myocarditis, Unspecified
+∞
8.3
8
*
FJA10
NOMESCO Finland
Transvenous biopsy of right ventricle
+∞
8.3
8
*
I42.1
ICD-10 Finland
Obstructive hypertrophic cardiomyopathy
+∞
8.3
8
*
I31.2
ICD-10 Finland
Haemopericardium, not elsewhere classified
+∞
8.3
8
*
4276B
ICD-9 Finland
Cardiac dysrhythmias, Premature beats[EXTRASYSTOLIA VENTRICULARIS]
+∞
8.3
8
*
B05DA
ATC
Isotonic solutions
8.6
8.3
17
20
I26.9
ICD-10 Finland
Pulmonary embolism without mention of acute cor pulmonale
2.4
8.2
67
288
C07AG02
ATC
carvedilol; oral
2.5
8.2
63
261
B34.9
ICD-10 Finland
Viral infection, unspecified
3.5
8.2
36
104
R03AK08
ATC
formoterol and beclometasone; inhalant
3.2
8.2
40
126
A02BA02
ATC
ranitidine; systemic
1.6
8.1
210
1380
C03EB01
ATC
furosemide and potassium-sparing agents; systemic
3.0
8.1
44
149
K57.3
ICD-10 Finland
Diverticular disease of large intestine without perforation or abscess
1.7
8.1
176
1103
B01AC06
ATC
acetylsalicylic acid; oral (platelet aggregation inhibitors excl. heparin)
2.8
8.0
48
173
SPAT1229
SPAT
Assessment of need for aid
2.2
8.0
81
385
M32.0
ICD-10 Finland
Drug-induced systemic lupus erythematosus
22.2
8.0
11
5
DM1AA
NOMESCO Finland
Paranasal sinuses X-ray examination without contrast
3.1
8.0
42
139
AA1
HP
Conventional CABG
4.6
8.0
26
57
C10AA01
ATC
simvastatin; oral
1.4
8.0
452
3535
R51.80
ICD-10 Finland
Headache
1.8
8.0
134
772
UJF30
NOMESCO Finland
Ileoscopy through colon
2.0
8.0
102
532
KA2AE
NOMESCO Finland
Ultrasound examination transplanted kidney
7.3
8.0
18
25
3AC01
NOMESCO Finland
NA
7.3
8.0
18
25
PA6DE
NOMESCO Finland
Neck artery ultrasound examination with Doppler method
2.7
7.9
51
192
B01AF03
ATC
edoxaban; oral
13.1
7.9
13
10
K52.9
ICD-10 Finland
Noninfective gastroenteritis and colitis, unspecified
2.9
7.9
46
163
SPAT1262
SPAT
Handing over of treatment supplies
1.6
7.9
194
1258
I49.8
ICD-10 Finland
Other specified cardiac arrhythmias
5.4
7.8
22
41
TPX10
NOMESCO Finland
Implantation of vascular injection port
3.3
7.8
38
119
TJA35
NOMESCO Finland
Removal of peritoneal dialysis catheter
10.9
7.8
14
13
NF1AE
NOMESCO Finland
Hip joint ultrasound examination
3.9
7.8
30
78
E0000UV
ATC
NA
1.5
7.7
384
2925
M32.1
ICD-10 Finland
Systemic lupus erythematosus with organ or system involvement
45.2
7.7
9
*
71
HP
Electrophysiological Special Examination
45.2
7.7
9
*
M54.6
ICD-10 Finland
Pain in thoracic spine
2.3
7.7
68
302
C03EA01
ATC
hydrochlorothiazide and potassium-sparing agents; oral
1.7
7.6
148
896
KA1MN
NOMESCO Finland
Glomerular filtration rate (GFR) Isotope mesurement
18.5
7.6
11
6
Z50.0
ICD-10 Finland
Cardiac rehabilitation
6.7
7.6
18
27
JN3BD
NOMESCO Finland
Extensive abdominal CT
1.9
7.6
115
643
L04AA01
ATC
[U] ciclosporin; systemic
4.5
7.6
25
56
Z95.8
ICD-10 Finland
Presence of other cardiac and vascular implants and grafts
25.2
7.6
10
*
I69.3
ICD-10 Finland
Sequelae of cerebral infarction
2.1
7.6
80
389
QDB10
NOMESCO Finland
Major dressing of wound of skin of lower limb
2.6
7.5
52
204
C08DB01
ATC
diltiazem; oral
2.5
7.5
56
230
R4190
NOMESCO Finland
Nutritional therapy
3.0
7.5
41
141
J22
ICD-10 Finland
Unspecified acute lower respiratory infection
2.6
7.4
52
206
H02AB09
ATC
hydrocortisone; systemic
3.7
7.4
30
82
SPAT1083
SPAT
Initiation and monitoring of IV fluid therapy
2.7
7.4
48
183
B01AC24
ATC
ticagrelor; oral
2.8
7.3
44
160
ZXE05
NOMESCO Finland
Procedure duration 40 to 49 minutes
2.4
7.3
61
266
R55
ICD-10 Finland
Syncope and collapse
1.9
7.3
103
560
ZXE04
NOMESCO Finland
Procedure duration 30 to 39 minutes
2.3
7.3
68
310
A40.3
ICD-10 Finland
Sepsis due to Streptococcus pneumoniae
10.9
7.3
13
12
FPH10
NOMESCO Finland
Open removal of transvenous cardiac pacemaker or cardioverter-defibrillator
+∞
7.3
7
*
TFE00
NOMESCO Finland
Pericardiocentesis
+∞
7.3
7
*
4270A
ICD-9 Finland
Cardiac dysrhythmias, Paroxysmal supraventricular tachycardia
+∞
7.3
7
*
4220A
ICD-9 Finland
Acute myocarditis in diseases classified elsewhere
+∞
7.3
7
*
FPE40
NOMESCO Finland
Replacement of transvenous cardiac pacemaker electrode
+∞
7.3
7
*
ATX
HP
Other pacemaker replacement or related action, such as cord removal or replacement
+∞
7.3
7
*
FPJ04
NOMESCO Finland
Revision of pacemaker generator with atrial and ventricular electrodes
+∞
7.3
7
*
FKC60
NOMESCO Finland
Resection and reconstruction of leaflet of mitral valve for insufficiency
+∞
7.3
7
*
FPG96
NOMESCO Finland
Other implantation of permanent cardioverter-defibrillator
+∞
7.3
7
*
I33.9
ICD-10 Finland
Acute endocarditis, unspecified
+∞
7.3
7
*
I38
ICD-10 Finland
Endocarditis, valve unspecified
+∞
7.3
7
*
Z95.3
ICD-10 Finland
Presence of xenogenic heart valve
+∞
7.3
7
*
K77
ICPC
Heart failure
9.4
7.3
14
15
NH3AA
NOMESCO Finland
Foot and toes X-ray examination
2.1
7.3
80
395
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
2.1
7.3
82
408
C02AC05
ATC
moxonidine; oral
2.6
7.3
50
195
M32.8
ICD-10 Finland
Other forms of systemic lupus erythematosus
15.8
7.2
11
7
PBL10
NOMESCO Finland
Construction of arteriovenous fistula from radial artery
5.8
7.2
19
33
GD1CD
NOMESCO Finland
Thorax extensive CT-examination
5.8
7.2
19
33
TKC20
NOMESCO Finland
Catheterisation of bladder
2.1
7.2
80
397
M10
ICD-10 Finland
Gout
2.6
7.2
48
186
J45.0
ICD-10 Finland
Predominantly allergic asthma
2.0
7.2
84
425
L30.9
ICD-10 Finland
Dermatitis, unspecified
1.6
7.2
172
1106
A41.5
ICD-10 Finland
Sepsis due to other Gram-negative organisms
3.1
7.1
37
123
B01AB10
ATC
tinzaparin; parenteral
2.2
7.1
70
331
WZC05
NOMESCO Finland
Specialty-specific consultation based on referral by dentist or doctor
2.4
7.1
56
237
M10.0
ICD-10 Finland
Idiopathic gout
3.2
7.1
35
112
B03XA03
ATC
methoxy polyethylene glycol-epoetin beta; parenteral
12.1
7.1
12
10
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
2.1
7.1
81
407
SAA02
NOMESCO Finland
Basic examination of mouth
1.4
7.1
644
5444
FNC20
NOMESCO Finland
Aorto-coronary venous bypass with two distal anastomoses
3.9
7.0
27
71
J01CF05
ATC
flucloxacillin; systemic
2.8
7.0
41
147
313
Kela drug reimbursment
Abatacept, adalimumab, anakinra, certolizumab pegol, etanercept, golimumab, infliximab, ixekizumab, sarilumab, secukinumab, tocilizumab and ustekinumab (rheumatoid diseases)
3.0
6.9
37
125
R11
ICD-10 Finland
Nausea and vomiting
2.1
6.9
76
377
Q21.10
ICD-10 Finland
Persistent ostium secundum
13.9
6.9
11
8
ND2AA
NOMESCO Finland
Hand and fingers X-ray examination
2.0
6.9
84
434
N30.0
ICD-10 Finland
Acute cystitis
1.8
6.9
118
689
Z01.0
ICD-10 Finland
Examination of eyes and vision
1.6
6.9
163
1044
ZXD30
NOMESCO Finland
Difficulties in perfomrming procedure
2.5
6.9
51
208
PD5AD
NOMESCO Finland
CT of aorta
4.8
6.9
21
44
JN3AD
NOMESCO Finland
Abdominal CT examination
2.1
6.8
79
397
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
1.8
6.8
119
696
A06AD11
ATC
lactulose; oral
1.7
6.8
155
982
J94.9
ICD-10 Finland
Pleural condition, unspecified
11.0
6.8
12
11
40199
ICD-8 Finland
Essential benign hypertension
4.5
6.8
22
49
J01FA10
ATC
azithromycin; systemic
1.4
6.8
563
4673
J01FA01
ATC
erythromycin; systemic
1.7
6.8
129
778
J01EE01
ATC
sulfamethoxazole and trimethoprim; systemic
2.2
6.7
67
317
I20.80
ICD-10 Finland
Other angina pectoris no detected stenosis of coronary artery
4.7
6.7
21
45
J10.0
ICD-10 Finland
Influenza with pneumonia, seasonal influenza virus identified
7.2
6.7
15
21
J01.0
ICD-10 Finland
Acute maxillary sinusitis
1.6
6.7
187
1252
WX110
NOMESCO Finland
Local anesthesy
1.4
6.7
708
6113
RS221
NOMESCO Finland
NA
3.8
6.7
26
69
IAZ97
NOMESCO Finland
Psychiatric consultation in another specialty
4.5
6.7
22
50
WYA30
NOMESCO Finland
Preparations for expected poor cooperation
2.0
6.6
80
412
J44.8
ICD-10 Finland
Other specified chronic obstructive pulmonary disease
1.8
6.6
105
596
L28
ICPC
Limited function/disability (L)
1.7
6.6
150
951
I45.0
ICD-10 Finland
Right fascicular block
12.3
6.6
11
9
I44.7
ICD-10 Finland
Left bundle-branch block, unspecified
12.3
6.6
11
9
FM2CE
NOMESCO Finland
NA
12.3
6.6
11
9
KA1AE
NOMESCO Finland
Kidney ultrasound examination
3.2
6.6
32
102
C07AB03
ATC
atenolol; systemic
2.2
6.6
61
281
J45.1
ICD-10 Finland
Nonallergic asthma
2.1
6.5
70
341
AN4
HP
Balloon angioplasty and drug eluding stent
2.8
6.5
39
142
A10BA02
ATC
metformin; oral
1.5
6.5
278
2042
N06AX11
ATC
mirtazapine; oral
1.4
6.5
303
2265
C09AA01
ATC
captopril; oral
4.0
6.5
24
61
I30
ICD-10 Finland
Acute pericarditis
70.2
6.4
7
*
FEC00
NOMESCO Finland
Pericardiopleurostomy
70.2
6.4
7
*
ZSF00
NOMESCO Finland
Procedure related to previous procedure classified in chapter F
70.2
6.4
7
*
D50.9
ICD-10 Finland
Iron deficiency anaemia, unspecified
2.1
6.4
65
311
NE1AA
NOMESCO Finland
Pelvis X-ray examination
2.1
6.4
67
324
R03BA05
ATC
fluticasone; inhalant
1.6
6.4
172
1139
C08CA05
ATC
nifedipine; systemic
2.0
6.4
74
375
JN3AA
NOMESCO Finland
Abdominal X-ray examination without contrast
2.4
6.4
52
225
K57.9
ICD-10 Finland
Diverticular disease of intestine, part unspecified, without perforation or abscess
3.3
6.4
29
88
C08CA02
ATC
felodipine; oral
1.9
6.4
94
523
4019X
ICD-9 Finland
Essential hypertension, Unspecified
3.0
6.4
34
116
K86.3
ICD-10 Finland
Pseudocyst of pancreas
8.2
6.3
13
16
EP1AE
NOMESCO Finland
Neck ultrasound examination
2.2
6.3
59
271
JN1CG
NOMESCO Finland
Extensive MRI examination of upper part of abdomen with high intensity magnet
3.0
6.3
33
111
WX000
NOMESCO Finland
Monitoring vital functions without anesthesy
2.7
6.3
39
146
FN1BB
NOMESCO Finland
Contrast angiography of heart and/or coronary arteries after bypass surgery
9.3
6.3
12
13
A28
ICPC
Limited function/disability NOS
1.7
6.3
137
859
FEC10
NOMESCO Finland
Pericardioperitoneostomy
+∞
6.3
6
*
FPG32
NOMESCO Finland
Implantation of cardioverter-defibrillator with atrial and ventricular electrodes
+∞
6.3
6
*
42099
ICD-8 Finland
NA
+∞
6.3
6
*
XF614
NOMESCO Finland
Measurement of pulmonary artery pressure
+∞
6.3
6
*
FKD10
NOMESCO Finland
Replacement of mitral valve using biological prosthesis
+∞
6.3
6
*
Z95.4
ICD-10 Finland
Presence of other heart-valve replacement
+∞
6.3
6
*
FKD00
NOMESCO Finland
Replacement of mitral valve using mechanical prosthesis
+∞
6.3
6
*
FEE00
NOMESCO Finland
Biopsy of pericardium
+∞
6.3
6
*
I20
ICD-10 Finland
Angina pectoris
4.3
6.2
21
49
PC1BD
NOMESCO Finland
Extensive CT of thoracic aorta
26.8
6.2
8
*
Z94.1
ICD-10 Finland
Heart transplant status
26.8
6.2
8
*
I45.9
ICD-10 Finland
Conduction disorder, unspecified
26.8
6.2
8
*
N39.0
ICD-10 Finland
Urinary tract infection, site not specified
1.7
6.2
129
798
ZXA00
NOMESCO Finland
Right side
1.5
6.2
273
2017
M01CB01
ATC
sodium aurothiomalate; parenteral
3.9
6.2
23
59
SPAT1249
SPAT
Treatment-related counselling outside office
1.4
6.2
379
2979
Z95.5
ICD-10 Finland
Presence of coronary angioplasty implant and graft
2.8
6.2
36
129
I95.9
ICD-10 Finland
Hypotension, unspecified
5.8
6.1
16
28
R5140
NOMESCO Finland
Monitoring the use of the aid
1.8
6.1
106
618
A03
ICPC
Fever
1.6
6.1
145
928
WX722
NOMESCO Finland
PEEP
2.4
6.1
48
205
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
1.6
6.1
160
1050
KA3AT
NOMESCO Finland
Biopsy of kidney with ultrasound guidance
4.1
6.1
22
55
NHQ40
NOMESCO Finland
Amputation of toe
3.9
6.1
23
60
WW500
NOMESCO Finland
Blood transfusion
2.5
6.0
44
181
K30
ICD-10 Finland
Functional dyspepsia
1.8
6.0
96
545

Mortality – FinRegistry

Association

Association between endpoint I9_PERICARD and mortality.

Females

Parameter HR [95% CI] p-value
I9_PERICARD 2.435 [2.09, 2.83] < 0.001
Birth year 0.992 [0.98, 1.0] 0.073

During the follow-up period (1.1.1998 — 31.12.2019), 816 out of 2298 females with I9_PERICARD died.

Males

Parameter HR [95% CI] p-value
I9_PERICARD 1.709 [1.5, 1.94] < 0.001
Birth year 0.991 [0.98, 1.0] 0.041

During the follow-up period (1.1.1998 — 31.12.2019), 844 out of 3737 males with I9_PERICARD died.

Mortality risk

Mortality risk for people of age

years, who have I9_PERICARD.

N-year risk Females Males
1 0.234% 0.323%
5 1.469% 2.054%
10 3.199% 5.322%
15 6.159% 10.534%
20 10.517% 17.41%

Relationships between endpoints

Index endpoint: I9_PERICARD – Pericarditis

GWS hits: 1

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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