Benign neoplasm: Parotid gland

CD2_BENIGN_PAROTID

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 D11.0&
  • Cause of death: ICD-10 D11.0&

2 out of 7 registries used, show all original rules.

3009

4. Check minimum number of events

None

3009

5. Include endpoints

None

3009

6. Filter based on genotype QC (FinnGen only)

3009

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
D11
Name in latin
Neoplasma benignum glandulae parotideae

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 17545 8978 8482
Only index persons 16470 8568 7902
Unadjusted period prevalence (%)
Whole population 0.25 0.26 0.24
Only index persons 0.31 0.31 0.30
Median age at first event (years)
Whole population 60.81 60.80 60.83
Only index persons 60.12 60.11 60.12

-FinnGen-

Key figures

All Female Male
Number of individuals 3009 1539 1470
Unadjusted period prevalence (%) 0.58 0.52 0.65
Median age at first event (years) 60.12 57.35 63.03

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
2701
Matched controls
27010
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
EP1AE
NOMESCO Finland
Neck ultrasound examination
12.8
323.0
653
658
ELB40
NOMESCO Finland
Partial parotidectomy
2510.6
323.0
1484
13
D11.0
ICD-10 Finland
Benign neoplasm: Parotid gland
4503599627370496.0
323.0
2698
*
R22.1
ICD-10 Finland
Localized swelling, mass and lump, neck
13.2
243.7
450
403
EL4AT
NOMESCO Finland
Salivary gland cytology with ultrasound guidance
254.7
229.9
233
10
ELB00
NOMESCO Finland
Excision or exploration of lesion of salivary gland
525.3
199.3
196
*
ELB50
NOMESCO Finland
Total parotidectomy
632.5
181.8
178
*
D37.00
ICD-10 Finland
Aryepiglottic fold marginal zone
97.5
165.4
182
20
EL3AE
NOMESCO Finland
Salivary gland ultrasound examination
43.8
122.9
153
37
WX408
NOMESCO Finland
General anesthesy, balanced
2.8
120.8
1032
4832
C07.70
ICD-10 Finland
Malignant tumor of the superficial part of the parotid gland
404.5
117.5
117
*
EP1CG
NOMESCO Finland
Extensive MRI examination of soft tissue of neck with high intesity magnet
19.2
110.8
172
95
XW1AT
NOMESCO Finland
Biopsy from other organ close to skin with ultrasound quidance
27.2
90.0
125
48
K11.2
ICD-10 Finland
Sialoadenitis
7.9
87.5
209
283
R22.0
ICD-10 Finland
Localized swelling, mass and lump, head
6.5
70.8
194
319
EP1DG
NOMESCO Finland
Very extensive examination of soft tissue of neck with high intesity magnet
20.7
66.5
100
50
ZXA05
NOMESCO Finland
Left side
2.1
57.5
826
4646
ZXA00
NOMESCO Finland
Right side
2.0
53.1
846
4935
R59.0
ICD-10 Finland
Localized enlarged lymph nodes
5.2
47.2
154
313
WX402
NOMESCO Finland
General anaesthesia
2.2
40.9
500
2564
D11.9
ICD-10 Finland
Benign neoplasm: Major salivary gland, unspecified
49.8
40.8
49
10
EP2AT
NOMESCO Finland
Neck soft tissue cytology with ultrasound guidance
24.8
39.8
56
23
R22.9
ICD-10 Finland
Localized swelling, mass and lump, unspecified
2.9
37.4
240
869
EL3AT
NOMESCO Finland
Salivary gland biopsy with ultrasound guidance
192.6
36.9
38
*
D11.70
ICD-10 Finland
Gland sublingual
24.1
36.7
52
22
C07.71
ICD-10 Finland
Malignant tumor in the deep part of the parotid gland
341.3
34.0
34
*
ELB99
NOMESCO Finland
Other excision of salivary gland
172.0
32.8
34
*
PJD81
NOMESCO Finland
Excision of lymph nodes from upper part of neck
13.0
31.6
56
44
J01DB01
ATC
cefalexin; oral
1.7
31.2
2133
18456
K11.9
ICD-10 Finland
Disease of salivary gland, unspecified
12.4
31.0
56
46
8550/3-C07.9
ICD-O-3
Acinar cell carcinoma of parotid gland
305.6
29.8
30
*
BA3AT
NOMESCO Finland
Cytology of thyroid with ultrasound quidance
6.1
27.9
77
129
WX110
NOMESCO Finland
Local anesthesy
1.6
27.3
1732
14358
N02BE01
ATC
paracetamol; systemic, rectal
1.7
26.4
2255
20101
QX4AT
NOMESCO Finland
Ultrsound guided needle biopsy of skin
10.6
25.8
50
48
PJ3AT
NOMESCO Finland
Cytology of lymphnode with ultrasound guidance
6.1
25.1
69
115
S04
ICPC
Lump/swelling localized
2.2
25.1
265
1257
PJD41
NOMESCO Finland
Excision of cervical lymph nodes
5.4
24.3
74
140
EN1BD
NOMESCO Finland
Very extensive CT examination of mouth and soft tissues of neck
5.0
24.2
79
162
8430/3-C07.9
ICD-O-3
Mucoepidermoid carcinoma of parotid gland
+∞
24.0
23
*
TDW99
NOMESCO Finland
Other minor procedure in surgery of ear, nose and larynx
3.3
23.2
119
369
Z71.2
ICD-10 Finland
Person consulting for explanation of investigation findings
1.7
23.1
585
3804
DWD00
NOMESCO Finland
Reoperation for superficial heamorrhage in surgery of ear, nose and larynx
36.6
23.0
29
8
S18
ICPC
Laceration/cut
1.5
22.8
1078
8198
L04.0
ICD-10 Finland
Acute lymphadenitis of face, head and neck
7.7
22.8
53
70
J44.8
ICD-10 Finland
Other specified chronic obstructive pulmonary disease
2.0
21.9
296
1559
2102A
ICD-9 Finland
Benign neoplasm of lip, oral cavity and pharynx, Major salivary glands
23.3
21.3
30
13
C08.89
ICD-10 Finland
Malignant overall tumor the large salivary glands anna or unspecified histology
100.7
18.6
20
*
ELB30
NOMESCO Finland
Excision of submandibular gland
8.8
18.4
39
45
R03BB04
ATC
tiotropium bromide; inhalant
1.9
18.2
279
1533
J01DA01
ATC
[U] cefalexin; systemic
1.4
17.0
1548
13140
EP1CM
NOMESCO Finland
Extensive MRI examination of soft tissue of neck with 3 Tesla magnet
20.2
16.4
24
12
4405
FHL
Partial removal of the parotid gland
18.6
16.0
24
13
UDQ12
NOMESCO Finland
Flexible laryngoscopy
2.3
15.7
154
702
UDC00
NOMESCO Finland
Ear microscopy
2.1
15.6
191
961
R59.1
ICD-10 Finland
Generalized enlarged lymph nodes
4.6
15.2
52
114
K11.3
ICD-10 Finland
Abscess of salivary gland
28.8
15.2
20
7
EN1AD
NOMESCO Finland
CT examination of mouth and soft tissues of neck
6.0
14.7
40
68
C08.99
ICD-10 Finland
Malignant tumor of unspecified large salivary gland, other or unspecified histology
80.5
14.6
16
*
TPJ05
NOMESCO Finland
Needle biopsy of lymph node
36.2
14.4
18
5
B02
ICPC
Lymph gland(s) enlarged/painful
6.9
13.9
34
50
CBK11
NOMESCO Finland
Operation for lagophtalmus with implant
23.9
13.8
19
8
C08.94
ICD-10 Finland
Mucoepidermoid carcinoma of an unspecified large salivary gland
+∞
13.5
13
*
TEL00
NOMESCO Finland
Needle biopsy of salivary gland
140.6
13.5
14
*
YA1BD
NOMESCO Finland
Extensive CT examination of head and neck for dose design of radiotherapy
5.3
13.3
40
77
K11.88
ICD-10 Finland
Other diseases of salivary glands
10.5
13.2
25
24
QAE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in head or neck
1.8
13.1
224
1279
WX404
NOMESCO Finland
Intravenous generell anesthesy
1.5
12.8
485
3431
Z72.0
ICD-10 Finland
Tobacco use
3.0
12.8
73
246
WZC00
NOMESCO Finland
Planning of intervention or health care consultation
1.4
12.6
770
5988
TQA05
NOMESCO Finland
Puncture of skin of head or neck
17.4
12.5
19
11
Q18.0
ICD-10 Finland
Sinus, fistula and cyst of branchial cleft
7.3
12.5
29
40
J44.0
ICD-10 Finland
Chronic obstructive pulmonary disease with acute lower respiratory infection
2.2
12.0
120
557
9699/3-C07.9
ICD-O-3
Marginal zone B-cell lymphoma, NOS, of parotid gland
+∞
11.5
11
*
EP1BG
NOMESCO Finland
MRI examination of soft tissue of neck with high intesity magnet
7.5
11.4
26
35
M01AE03
ATC
ketoprofen; systemic, rectal
1.4
11.4
897
7250
ZXC99
NOMESCO Finland
Other special technic in surgery
15.1
11.3
18
12
SPAT1153
SPAT
Removal of sutures
1.4
11.2
775
6131
WF003
NOMESCO Finland
Adjuvant radiotherapy
2.4
11.2
95
409
C83.80
ICD-10 Finland
B-cell lymphoma in marginal zone
8.6
11.0
23
27
EP1DM
NOMESCO Finland
Very extensive MRI examination of soft tissue of neck with 3 Tesla magnet
21.5
10.7
15
7
R4110
NOMESCO Finland
Physiotherapy
1.4
10.7
605
4617
K11.4
ICD-10 Finland
Fistula of salivary gland
60.2
10.6
12
*
AAH50
NOMESCO Finland
Cranial nerve anastomosis
60.2
10.6
12
*
R91
ICD-10 Finland
Abnormal findings on diagnostic imaging of lung
1.7
10.6
240
1491
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
1.6
10.6
256
1624
J44.1
ICD-10 Finland
Chronic obstructive pulmonary disease with acute exacerbation, unspecified
2.4
10.3
86
365
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.3
10.3
927
7621
D44.0
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Thyroid gland
3.8
10.3
42
112
21020
ICD-8 Finland
Benign neoplasm of buccal cavity and pharynx, Salivary gland
9.6
10.2
20
21
UDH02
NOMESCO Finland
Rhinopharyngoscopy
1.9
9.9
151
830
JN4KR
NOMESCO Finland
Whole body very extensive metabolic PET with CT
5.0
9.8
30
60
PJD71
NOMESCO Finland
Extended sparing excision of cervical lymph nodes
6.3
9.8
25
40
XX3DW
NOMESCO Finland
Time consuming IT work
1.6
9.4
240
1542
D14.0
ICD-10 Finland
Benign neoplasm: Middle ear, nasal cavity and accessory sinuses
4.5
9.4
32
72
C82.1
ICD-10 Finland
Follicular lymphoma grade II
5.0
9.4
29
59
8500/3-C07.9
ICD-O-3
Infiltrating duct carcinoma, NOS, of parotid gland
+∞
9.4
9
*
J44.9
ICD-10 Finland
Chronic obstructive pulmonary disease, unspecified
2.0
9.4
112
563
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.3
9.3
1035
8731
C85.9
ICD-10 Finland
Non-Hodgkin lymphoma, unspecified
5.6
9.3
26
47
N02AX02
ATC
tramadol; systemic, rectal
1.3
9.3
989
8299
K11.5
ICD-10 Finland
Sialolithiasis
3.5
9.2
41
118
EP1AE
SPAT
NA
3.5
9.1
40
114
203
Kela drug reimbursment
Chronic asthma and similar chronic obstructive pulmonary diseases
1.4
9.0
421
3092
R03AC02
ATC
salbutamol; inhalant
1.3
8.9
1174
10113
N07BA03
ATC
varenicline; oral
1.9
8.9
117
613
A07AA02
ATC
nystatin; oral
1.8
8.8
147
835
YA1CD
NOMESCO Finland
Very extensive CT examination of head and neck for dose design of radiotherapy
8.6
8.8
18
21
K05.31
ICD-10 Finland
Periodontitis pronounced
1.6
8.7
220
1407
UGC12
NOMESCO Finland
Flexible bronchoscopy
1.7
8.7
183
1113
E04.2
ICD-10 Finland
Nontoxic multinodular goitre
2.2
8.7
87
407
SAA03
NOMESCO Finland
Extended examination of mouth
1.3
8.7
823
6777
I70.2
ICD-10 Finland
Atherosclerosis of arteries of extremities
1.6
8.6
209
1326
L28
ICPC
Limited function/disability (L)
1.5
8.6
345
2458
ELW99
NOMESCO Finland
Other operation on salivary gland
27.6
8.5
11
*
E11.9
ICD-10 Finland
Type 2 diabetes mellitus, without complications
1.4
8.4
537
4160
C07
ICD-10 Finland
Malignant neoplasm of parotid gland
90.3
8.4
9
*
8070/3-C07.9
ICD-O-3
Squamous cell carcinoma, NOS, of parotid gland
+∞
8.3
8
*
J01FF01
ATC
clindamycin; systemic
1.3
8.3
610
4832
ELA30
NOMESCO Finland
Biopsy of salivary gland
9.5
8.3
16
17
QAA99
NOMESCO Finland
Other local destruction of skin of head or neck
7.5
8.1
18
24
DEB00
NOMESCO Finland
Cortical mastoidectomy
33.4
8.1
10
*
PJD91
NOMESCO Finland
Excision of lymph nodes in neck, 1 to 2 areas in total
17.2
8.1
12
7
H02AB06
ATC
prednisolone; systemic
1.3
8.0
1071
9206
D21.0
ICD-10 Finland
Benign neoplasm: Connective and other soft tissue of head, face and neck
6.3
8.0
20
32
EWE00
NOMESCO Finland
Reoperation for deep haemorrhage in surgery of teeth, jaws, mouth and pharynx
13.1
7.9
13
10
UDQ22
NOMESCO Finland
Microlaryngoscopy
4.5
7.9
26
58
YA1AD
NOMESCO Finland
CT examination of head and neck for dose design of radiotherapy
4.4
7.7
26
59
Z01.8
ICD-10 Finland
Other specified special examinations
1.4
7.7
477
3675
QAA05
NOMESCO Finland
Incision for biopsy of skin of head or neck
2.4
7.7
61
257
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.3
7.7
1043
8969
WX707
NOMESCO Finland
Fiberoscopic intubation
7.4
7.7
17
23
XW1XT
NOMESCO Finland
Biopsy from other organ close to skin with other quidance
80.3
7.4
8
*
8200/3-C07.9
ICD-O-3
Adenoid cystic carcinoma of parotid gland
80.3
7.4
8
*
D11
ICD-10 Finland
Benign neoplasm of major salivary glands
80.3
7.4
8
*
WZC30
NOMESCO Finland
Teaching
1.5
7.4
289
2047
M35.0
ICD-10 Finland
Sicca syndrome [Sjögren]
2.6
7.3
51
200
8147/3-C07.9
ICD-O-3
Basal cell adenocarcinoma of parotid gland
+∞
7.3
7
*
ELB60
NOMESCO Finland
Radical parotidectomy sacrificing the facial nerve
+∞
7.3
7
*
8941/3-C07.9
ICD-O-3
Carcinoma ex pleomorphic adenoma of parotid gland
+∞
7.3
7
*
C03CA01
ATC
furosemide; systemic
1.3
7.3
646
5248
TQW40
NOMESCO Finland
Remowal of suture of skin
1.7
7.2
152
928
J01AA02
ATC
doxycycline; systemic
1.3
7.2
1913
17737
K11
ICD-10 Finland
Diseases of salivary glands
15.8
7.2
11
7
EP1AT
NOMESCO Finland
Punction of soft tissue of neck with ultrasound guidance
15.8
7.2
11
7
G51.0
ICD-10 Finland
Bell palsy
2.3
7.2
61
266
M01AE01
ATC
ibuprofen; systemic, rectal
1.3
7.2
2201
20789
4404
FHL
Complete removal of the parotid gland
20.1
7.1
10
5
GD1BD
NOMESCO Finland
Thorax extensive CT-examination
1.8
7.1
125
724
L72.1
ICD-10 Finland
Trichilemmal cyst
1.7
7.1
137
817
D17.0
ICD-10 Finland
Benign lipomatous neoplasm of skin and subcutaneous tissue of head, face and neck
2.6
7.0
46
176
A10BA02
ATC
metformin; oral
1.3
7.0
632
5146
EBA05
NOMESCO Finland
Complicated extraction of tooth
1.4
7.0
400
3041
H60.8
ICD-10 Finland
Other otitis externa
2.3
6.9
61
270
C73.91
ICD-10 Finland
Papillary carcinoma of the thyroid gland (thyroid gland)
2.9
6.9
40
140
8260/3-C73.9
ICD-O-3
Papillary adenocarcinoma, NOS, of thyroid gland
3.0
6.9
37
125
WZC20
NOMESCO Finland
Multidisciplinary treatment meeting
1.8
6.9
120
696
C08.90
ICD-10 Finland
Malignant tumor in unspecified large salivary gland without histology
40.1
6.8
8
*
ZZK00
NOMESCO Finland
Graft of nerve
40.1
6.8
8
*
P01AB01
ATC
metronidazole; oral, rectal
1.3
6.7
862
7326
EP3AT
NOMESCO Finland
Neck soft tissue biopsy with ultrasound guidance
16.7
6.7
10
6
R06.0
ICD-10 Finland
Dyspnoea
1.3
6.7
534
4264
A02BC02
ATC
pantoprazole; systemic
1.2
6.7
1534
13917
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.2
6.7
1118
9798
BAA60
NOMESCO Finland
Total thyroidectomy
2.3
6.6
56
242
R03AL09
ATC
formoterol, glycopyrronium bromide and beclometasone; inhalant
2.6
6.6
45
176
H92.0
ICD-10 Finland
Otalgia
1.9
6.6
97
532
SBA00
NOMESCO Finland
Microbiological examinations
2.4
6.6
53
225
J01CE02
ATC
phenoxymethylpenicillin; oral
1.2
6.6
1594
14539
Z01.1
ICD-10 Finland
Examination of ears and hearing
1.4
6.6
285
2061
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
1.2
6.5
908
7790
EBA00
NOMESCO Finland
Extraction of tooth
1.3
6.5
692
5750
D11.7
ICD-10 Finland
Benign neoplasm: Other major salivary glands
70.0
6.4
7
*
ELB70
NOMESCO Finland
Excision of parotid gland neoplasm or other lesion extending into parapharyngeal space
70.0
6.4
7
*
C77.0
ICD-10 Finland
Secondary and unspecified malignant neoplasm: Lymph nodes of head, face and neck
4.1
6.4
23
57
R52.9
ICD-10 Finland
Pain, unspecified
1.6
6.3
173
1134
QAE99
NOMESCO Finland
Other excision or repair surgery of skin and subcutaneous tissue in head and neck
2.2
6.3
57
257
R02
ICPC
Shortness of breath/dyspnoea
1.4
6.3
253
1802
SCA04
NOMESCO Finland
Guidance on care of mouth and oral mucosa
9.3
6.3
12
13
QAE30
NOMESCO Finland
Excision and repair of surgical scar in head or neck
9.3
6.3
12
13
K11.0
ICD-10 Finland
Atrophy of salivary gland
+∞
6.2
6
*
8562/3-C07.9
ICD-O-3
Epithelial-myoepithelial carcinoma of parotid gland
+∞
6.2
6
*
D36.0
ICD-10 Finland
Benign neoplasm: Lymph nodes
+∞
6.2
6
*
8502/3-C07.9
ICD-O-3
Secretory carcinoma of parotid gland
+∞
6.2
6
*
A02BC01
ATC
omeprazole; systemic
1.3
6.2
605
4962
L02.1
ICD-10 Finland
Cutaneous abscess, furuncle and carbuncle of neck
3.8
6.2
24
64
N30.0
ICD-10 Finland
Acute cystitis
1.4
6.2
269
1949
K04.5
ICD-10 Finland
Chronic apical periodontitis
1.3
6.1
538
4354
S10
ICPC
Boil/carbuncle
1.7
6.1
111
655
C64.88
ICD-10 Finland
Other malignant neoplasm of kidney, except renal pelvis
2.3
6.1
50
216
R60.0
ICD-10 Finland
Localized oedema
1.5
6.1
228
1604
G47.3
ICD-10 Finland
Sleep apnoea
1.3
6.0
461
3657
K11.1
ICD-10 Finland
Hypertrophy of salivary gland
10.0
6.0
11
11
J45.9
ICD-10 Finland
Asthma, unspecified
1.4
6.0
367
2816
215
Kela drug reimbursment
Diabetes, non-insulin-treated
1.3
6.0
538
4364

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
727
598
15.71
307.65
1.4
1.2
—
—
—
0
0
504
2225
2.52
69.80
1.5
1.4
—
—
—
0
0
1451
10167
1.82
55.48
2.3
2.1
—
—
—
0
0
622
3320
2.10
53.68
1.3
1.3
—
—
—
0
0
1492
11790
1.53
27.80
6.3
5.9
58.0
57.6
%
0.67
1374
11024
1474
11691
1.51
26.50
6.6
6.3
8.9
8.8
%
0.95
1358
10944
1551
12457
1.51
26.09
6.2
5.8
0.0
0.0
e9/l
0.30
1326
10733
1464
11639
1.50
25.74
6.4
6.0
2.9
2.8
%
0.03
1343
10843
1499
11977
1.50
25.71
6.5
6.1
26.9
27.4
%
0.94
1376
11149
1430
11322
1.50
25.60
6.5
6.1
0.7
0.7
%
0.57
1319
10561
1539
12404
1.49
25.03
6.2
5.7
0.6
0.6
e9/l
1.80
1313
10678
1571
12731
1.49
24.76
6.3
5.8
1.9
1.9
e9/l
0.89
1372
11165
1586
12885
1.49
24.63
6.6
6.0
0.2
0.2
e9/l
0.09
1379
11250
477
2954
1.73
24.26
1.8
1.8
—
—
—
0
0
1740
14479
1.48
23.42
9.8
9.0
4.3
4.2
e9/l
0.95
1521
12614
1537
12738
1.42
19.52
7.6
6.9
1.2
1.2
mmol/l
0.05
1312
10709
1443
11865
1.42
18.94
4.2
4.1
—
—
—
0
0
1754
14956
1.41
18.50
6.0
4.9
6.8
6.8
mmol/l
0.54
1661
14060
1033
8047
1.43
18.15
2.6
2.5
—
—
—
0
0
848
6422
1.45
17.16
4.8
3.9
88.0
89.0
%
0.48
840
6266
1118
8904
1.41
17.06
4.3
3.8
99.0
103.2
e6/l
0.04
780
6406
1401
11602
1.39
16.91
7.1
6.1
1.2
1.2
mmol/l
0.27
1288
10487
2171
19449
1.42
15.75
8.7
7.7
79.8
78.5
u/l
0.49
2062
18346
965
7591
1.40
15.45
4.4
4.1
7.4
7.4
ph
1.09
179
1474
1074
8606
1.39
15.38
6.3
5.8
—
—
—
0
0
1317
10939
1.36
14.94
11.1
9.8
0.0
0.0
e9/l
1.97
1085
8936
2637
24621
1.57
14.73
18.5
15.0
24.6
24.6
mg/l
0.03
2211
19695
2441
22464
1.46
14.26
5.3
4.7
2.8
2.1
mu/l
0.34
2234
20437
559
4043
1.47
14.02
3.6
3.0
2.4
2.3
e6/l
0.09
302
2216
895
7054
1.38
13.84
3.5
3.2
0.3
0.5
e6/l
1.80
655
5373
66
235
2.85
13.80
1.4
1.2
—
—
—
0
0
965
7705
1.37
13.75
3.7
3.3
48.6
82.1
e6/l
0.92
723
5968
1320
11075
1.34
13.57
5.1
4.9
35.2
35.3
g/l
0.30
1212
10291
1854
16387
1.34
13.21
5.1
4.6
3764.4
1518.1
e6/l
0.31
32
241
867
6847
1.37
13.10
3.5
3.1
—
—
—
0
0
2053
18437
1.36
13.10
4.7
4.1
13.3
12.7
mm/h
1.18
1910
17035
1922
17116
1.34
12.80
4.8
4.4
—
—
—
0
0
584
4326
1.43
12.79
3.3
2.8
1.7
1.1
e6/l
0.43
327
2490
343
2289
1.56
12.53
1.6
1.5
—
—
—
0
0
790
6199
1.37
12.29
2.6
2.4
—
—
—
0
0
1537
13314
1.32
12.11
7.0
6.3
11.1
11.5
umol/l
0.57
1485
12644
504
3675
1.45
11.95
2.1
2.1
—
—
—
0
0
1255
10596
1.32
11.79
10.6
9.8
1.2
1.3
inr
0.69
362
3029
47
152
3.13
11.67
6.7
6.6
—
—
—
0
0
2062
18689
1.33
11.35
4.4
4.0
15.1
14.8
pmol/l
3.21
1864
16894
790
6302
1.34
10.82
7.5
6.7
—
—
—
0
0
2703
25667
1.52
10.81
21.0
17.5
4.0
4.0
mmol/l
0.38
2646
24983
2697
25609
1.51
10.67
20.9
17.4
139.6
139.7
mmol/l
0.21
2646
24963
1038
8624
1.31
10.66
3.8
3.4
2.4
2.4
mmol/l
0.01
910
7510
874
7158
1.31
9.79
4.8
4.4
—
—
—
0
0
219
1396
1.61
9.70
12.2
10.0
24.5
24.4
mmol/l
0.20
203
1312
55
220
2.53
9.29
6.0
5.0
107.0
52.4
u/ml
0.31
18
60
443
3304
1.40
9.10
9.0
7.1
104.7
104.3
mmol/l
1.01
429
3227
2184
20181
1.30
9.08
22.3
18.2
13.9
13.8
%
1.97
2143
19716
596
4729
1.32
8.17
3.3
3.1
2.5
2.5
mmol/l
0.50
526
4170
453
3449
1.37
8.17
5.3
5.9
1.0
1.0
mmol/l
0.99
414
3200
407
3051
1.39
8.07
9.6
7.6
5.3
5.1
kpa
2.26
389
2914
407
3051
1.39
8.07
9.6
7.6
12.5
12.1
kpa
0.59
388
2913
1176
10186
1.25
8.03
2.4
2.2
77.1
77.9
nmol/l
0.37
1051
9079
1207
10488
1.25
8.00
2.0
2.0
92.8
94.5
pmol/l
0.61
662
5469
1933
17706
1.26
7.99
4.2
3.9
—
—
—
0
0
405
3039
1.38
7.98
9.6
7.6
1.2
1.1
mmol/l
0.15
321
2382
541
4247
1.33
7.97
3.4
3.3
0.8
0.8
mmol/l
0.92
505
3970
322
2328
1.43
7.86
2.6
2.4
37.1
59.2
u/l
0.55
279
2010
1364
12039
1.24
7.79
5.6
5.0
0.0
0.0
estimate
0.50
258
2284
74
364
2.06
7.76
1.8
1.6
0.8
0.8
g/l
0.02
54
276
2726
26185
1.44
7.65
21.3
17.6
78.6
79.1
umol/l
0.42
2726
26175
298
2144
1.43
7.48
11.0
8.7
—
—
—
0
0
2728
26225
1.43
7.45
12.3
10.7
25.8
26.2
u/l
0.72
2640
25271
2811
27182
1.52
7.42
26.4
22.0
248.6
248.1
e9/l
0.14
2738
26462
2812
27201
1.52
7.32
26.4
22.1
7.0
6.8
e9/l
4.76
2727
26387
2811
27195
1.51
7.25
26.4
22.0
4.5
4.5
e12/l
0.45
2725
26384
2811
27201
1.51
7.18
26.6
22.2
135.1
135.1
g/l
0.00
2773
26785
2810
27191
1.51
7.16
26.3
22.0
91.4
91.3
fl
0.98
2768
26772
1371
12188
1.23
7.08
4.2
3.7
0.0
0.0
estimate
1.08
249
2202
1354
12023
1.23
7.06
4.1
3.7
0.0
0.0
estimate
0.00
252
2247
895
7602
1.25
7.04
3.0
3.1
1613.5
1500.6
ng/l
0.22
786
6512
2809
27193
1.50
6.99
26.3
21.9
30.4
30.4
pg
0.02
2768
26771
618
5027
1.29
6.94
3.0
2.8
552.8
549.9
mosm/kgh2o
0.11
521
4277
912
7788
1.25
6.79
2.2
2.2
181.9
243.7
u/l
1.53
860
7304
361
2734
1.36
6.69
10.3
8.0
95.3
95.6
%
0.41
354
2635
652
5362
1.28
6.69
4.9
4.5
—
—
—
0
0
657
5412
1.27
6.65
2.6
2.6
4.4
5.4
e6/l
1.58
560
4755
260
1867
1.43
6.60
2.9
2.7
10.9
10.6
g/l
0.57
237
1694
320
2385
1.38
6.55
7.2
7.4
9.9
10.2
mmol/l
0.39
306
2269
308
2284
1.39
6.50
9.6
7.3
1.3
1.4
mmol/l
0.22
299
2200
1069
9328
1.23
6.42
3.7
3.4
—
5.8
—
0
6
2654
25501
1.35
6.33
16.1
14.2
—
—
—
0
0
386
2985
1.34
6.24
2.6
2.5
1.8
1.8
%
0.08
337
2653
946
8177
1.23
6.17
4.2
4.0
8.6
9.0
mg/mmol
0.10
636
5173
276
2031
1.40
6.10
3.9
4.2
0.2
0.1
%
0.54
68
586
205
1437
1.46
5.94
3.7
3.4
4.3
4.4
pmol/l
1.32
186
1262
210
1479
1.45
5.93
1.7
1.8
1.3
1.4
g/l
0.18
188
1340
261
1913
1.40
5.91
3.9
4.2
1.4
0.4
%
0.33
53
494
217
1544
1.44
5.81
9.1
7.6
25.0
24.9
mmol/l
0.07
211
1536
312
2363
1.36
5.78
3.7
3.7
2.0
2.0
mmol/l
0.06
249
1892
22
70
3.16
5.74
1.0
1.1
—
—
—
0
0
713
6023
1.24
5.70
1.6
1.6
20.3
20.5
nmol/l
0.07
612
5132
875
7554
1.22
5.69
3.8
3.2
—
—
—
0
0
119
750
1.61
5.63
3.3
3.4
—
—
—
0
0
321
2452
1.35
5.63
2.6
2.1
0.2
0.2
g/l
1.24
298
2290
680
5731
1.24
5.54
3.8
3.6
—
—
—
0
0
311
2373
1.35
5.50
3.7
3.7
6.1
5.9
kpa
2.78
305
2299
284
2138
1.36
5.48
3.9
4.1
1.3
0.9
%
1.09
72
634
604
5030
1.25
5.47
4.0
3.8
821.8
577.3
ng/l
0.33
498
4015
127
820
1.57
5.45
2.3
3.5
1.4
2.4
ratio
0.75
12
68
222
1610
1.41
5.36
1.3
1.4
—
—
—
0
0
104
643
1.64
5.34
2.0
3.7
—
—
—
0
0
754
6453
1.22
5.28
2.2
2.2
3.0
3.0
mg/l
0.05
629
5501
649
5477
1.24
5.19
1.7
1.8
1.5
1.3
mg/l
0.92
497
4211
172
1198
1.46
5.18
3.6
3.9
24.3
24.1
mmol/l
0.24
152
1067
438
3533
1.28
5.17
1.2
1.2
—
—
—
0
0
924
8094
1.20
5.07
3.3
3.2
7.5
7.5
mmol/l
0.05
774
6781
246
1836
1.37
5.02
2.0
2.5
—
—
—
0
0
128
845
1.54
5.00
2.3
3.5
54.7
129.6
mg/l
0.56
98
684
128
845
1.54
5.00
2.3
3.5
33.0
71.4
mg/l
1.47
99
686
2404
22966
1.23
4.95
6.7
6.0
40.6
40.1
mmol/mol
2.09
2214
21172
889
7775
1.20
4.94
3.3
3.3
487.8
296.7
mg/l
0.53
597
4931
46
228
2.03
4.86
1.5
1.4
7.4
6.9
g/l
0.31
30
156
46
228
2.03
4.86
1.5
1.4
0.4
0.4
g/l
0.36
30
156
46
228
2.03
4.86
1.5
1.4
3.0
2.9
g/l
0.01
30
156
359
2846
1.30
4.85
3.4
2.7
9.2
8.4
umol/l
0.22
311
2487
137
928
1.50
4.77
2.2
2.3
321.0
715.9
ug/l
1.00
131
877
46
230
2.02
4.75
1.5
1.4
—
—
—
0
0
483
3985
1.25
4.71
2.1
2.1
30.4
29.9
s
1.21
472
3860
323
2536
1.31
4.69
11.1
8.4
120.6
121.6
g/l
0.38
315
2444
139
948
1.49
4.68
1.9
2.5
10.3
10.3
g/l
0.01
121
817
399
3226
1.27
4.62
1.4
1.3
675.6
533.0
titre
0.65
100
693
257
1972
1.33
4.40
3.5
3.9
88.9
92.3
ng/l
0.25
216
1704
56
309
1.83
4.36
1.2
1.3
—
—
—
0
0
451
3725
1.25
4.35
2.5
2.5
2.3
2.3
g/l
0.34
414
3458
283
2212
1.31
4.26
2.2
2.7
66.6
66.4
g/l
0.17
259
2026
253
1947
1.33
4.25
3.6
3.9
1.1
0.6
%
0.81
46
456
776
6787
1.19
4.21
2.5
2.7
5049.5
5177.5
umol/l
0.03
669
5872
349
2814
1.27
4.13
1.3
1.3
—
—
—
0
0
479
4008
1.23
4.09
2.4
2.5
12.9
12.9
umol/l
0.02
440
3721
30
135
2.23
4.08
1.5
2.9
7.4
7.4
ph
—
9
49
1138
10298
1.17
4.08
2.9
2.8
138.0
139.5
ug/l
0.05
1040
9478
249
1932
1.31
3.96
3.2
2.9
4.6
4.6
kpa
0.15
242
1866
69
419
1.66
3.89
1.2
1.2
—
—
—
0
0
1706
15968
1.16
3.81
3.5
3.1
54.2
51.2
u/l
0.57
1591
14792
47
258
1.83
3.76
3.2
3.4
—
—
—
0
0
309
2485
1.27
3.75
1.4
1.6
—
—
—
0
0
116
801
1.47
3.74
2.0
2.3
38.2
37.6
g/l
0.45
100
701
419
3492
1.23
3.72
2.6
2.6
21.5
22.7
%
1.26
361
2984
30
141
2.14
3.70
1.6
2.2
—
—
—
0
0
364
2992
1.25
3.67
1.6
1.4
—
—
—
0
0
282
2252
1.28
3.63
2.6
2.6
73.7
70.1
e9/l
0.68
211
1716
97
653
1.50
3.56
3.4
2.9
1.6
1.6
mg/l
0.20
86
595
73
461
1.60
3.56
1.3
1.5
—
—
—
0
0
29
138
2.11
3.49
1.4
1.6
—
—
—
0
0
150
1101
1.38
3.47
1.2
1.2
—
—
—
0
0
87
578
1.52
3.41
2.2
2.2
127.7
129.3
g/l
0.24
68
416
417
3507
1.22
3.39
1.6
1.7
—
—
—
0
0
358
2965
1.24
3.37
1.4
1.6
—
—
—
0
0
1084
9881
1.15
3.37
4.1
3.7
38.3
56.5
ng/l
1.18
762
7002
523
4498
1.20
3.37
1.5
1.5
2.6
2.5
g/l
0.36
312
2754
410
3450
1.22
3.32
25.4
25.6
1.3
1.4
inr
0.82
53
491
891
8016
1.16
3.30
2.7
2.6
52.1
57.6
u/l
3.70
828
7404
281
2274
1.26
3.26
2.4
2.2
385.0
371.7
nmol/l
0.46
259
2082
41
229
1.80
3.16
2.0
2.2
1.1
1.1
e9/l
0.04
28
143
54
328
1.66
3.11
3.0
2.2
1571.6
176.6
u/ml
0.70
54
316
42
241
1.75
2.98
2.0
1.4
16.4
31.1
iu/ml
—
5
11
27
134
2.02
2.95
1.1
1.3
—
—
—
0
0
2293
22104
1.16
2.92
20.2
16.0
39.7
39.6
%
0.21
1624
15318
326
2720
1.22
2.88
3.9
4.1
31.8
23.0
ug/l
0.16
284
2229
747
6693
1.15
2.88
1.7
1.6
1.4
1.4
mmol/l
0.42
633
5597
223
1784
1.27
2.87
5.3
4.9
—
—
—
0
0
476
4121
1.18
2.84
1.3
1.3
56.0
35.3
iu/ml
0.86
162
1306
18
77
2.35
2.81
2.3
2.3
26.7
29.6
%
0.44
18
70
50
307
1.64
2.79
1.4
1.5
—
—
—
0
0
23
110
2.10
2.78
1.6
1.2
—
—
—
0
0
116
850
1.38
2.78
1.2
1.3
34.3
30.7
iu/l
0.47
97
733
122
902
1.37
2.77
1.5
1.2
0.6
1.1
u/ml
—
9
80
83
573
1.46
2.77
2.6
2.5
15.8
16.1
%
0.28
46
282
40
232
1.73
2.76
1.1
1.2
—
—
—
0
0
82
566
1.46
2.74
1.6
1.7
—
—
—
0
0
173
1349
1.30
2.74
3.2
2.9
0.2
0.3
e6/l
0.84
167
1313
2127
20432
1.14
2.72
23.9
19.3
331.6
332.3
g/l
2.61
2106
20275
260
2142
1.23
2.61
4.4
3.9
1.2
1.2
mmol/l
3.33
230
1862
455
3954
1.18
2.60
1.3
1.2
13.8
12.5
u/ml
0.13
173
1514
21
100
2.11
2.58
3.5
2.5
—
—
—
0
0
29
156
1.87
2.56
3.2
3.5
—
—
—
0
0
32
178
1.81
2.55
2.2
2.2
14.4
14.3
%
0.01
17
69
32
178
1.81
2.55
1.2
1.3
13.8
12.1
mmol/l
0.47
14
59
273
2269
1.22
2.53
2.5
2.9
215.7
203.7
ng/l
0.19
238
2070
10
33
3.04
2.52
1.3
1.5
44.4
41.2
umol/l
—
10
33
24
123
1.96
2.45
1.2
1.1
9.6
14.0
iu/ml
—
7
39
17
76
2.24
2.44
1.1
1.8
—
—
—
0
0
16
70
2.29
2.41
4.6
5.3
—
—
—
0
0
40
242
1.66
2.41
2.2
2.4
—
—
—
0
0
714
6454
1.14
2.39
3.9
3.4
—
—
—
0
0
28
153
1.84
2.38
1.4
1.3
—
—
—
0
0
11
40
2.76
2.37
1.4
1.1
—
—
—
0
0
17
77
2.21
2.37
2.4
2.3
7.4
8.9
%
0.30
17
68
84
602
1.41
2.34
3.6
3.8
—
—
—
0
0
220
1805
1.24
2.33
1.4
1.4
—
—
—
0
0
82
586
1.41
2.32
1.7
1.9
4.2
4.7
iu/l
0.14
26
202
56
373
1.51
2.28
2.5
2.6
—
—
—
0
0
30
171
1.76
2.24
1.2
1.1
—
—
—
0
0
123
946
1.31
2.21
3.8
3.4
1279.1
4254.4
u/ml
0.47
108
809
53
353
1.51
2.17
2.2
2.6
—
—
—
0
0
179
1449
1.25
2.15
1.5
1.3
328.4
214.1
u/ml
0.93
164
1334
16
74
2.17
2.14
1.0
1.1
—
—
—
0
0
147
1164
1.28
2.13
2.7
2.5
0.7
0.7
%
0.03
138
1112
5
10
5.01
2.07
1.2
1.0
—
—
—
0
0
2471
24103
1.14
2.07
4.9
4.7
6.1
6.0
mmol/l
3.59
2238
21871
69
490
1.42
2.06
1.3
1.4
—
—
—
0
0
16
76
2.11
2.02
1.0
1.0
—
—
—
0
0
10
38
2.64
2.01
1.2
1.5
59.7
122.7
ng/l
—
10
38
44
289
1.53
1.95
1.7
1.4
13597.5
88524.9
e6/l
1.77
23
172
38
243
1.57
1.90
1.5
1.5
—
—
—
0
0
12
52
2.31
1.87
1.0
1.6
—
—
—
0
0
132
1053
1.27
1.84
3.0
2.6
—
—
—
0
0
84
631
1.34
1.82
1.3
1.2
—
—
—
0
0
41
270
1.53
1.81
1.2
1.3
284.4
277.5
mosm/kgh2o
2.07
36
202
15
73
2.06
1.80
2.7
2.2
—
—
—
0
0
28
168
1.67
1.80
2.2
1.3
—
—
—
0
0
104
808
1.30
1.79
5.9
4.1
3.9
3.9
mmol/l
0.01
90
756
20
109
1.84
1.77
1.3
1.1
—
—
—
0
0
203
1705
1.20
1.76
2.6
3.2
4.3
4.1
e9/l
0.50
147
1314
63
457
1.39
1.72
3.3
3.2
—
—
—
0
0
82
622
1.33
1.69
4.2
4.7
8.4
8.5
kpa
0.08
76
614
42
283
1.49
1.69
1.6
1.6
—
—
—
0
0
2541
24903
1.13
1.69
5.3
5.1
2.7
2.7
mmol/l
2.15
2329
22834
45
308
1.47
1.68
2.5
2.4
—
—
—
0
0
43
292
1.48
1.67
1.5
1.3
48.5
47.7
u/ml
—
5
16
175
1458
1.21
1.67
13.0
10.5
—
—
—
0
0
75
564
1.34
1.65
3.8
3.1
1.7
1.6
mmol/l
0.58
75
545
63
461
1.37
1.64
1.3
1.4
—
—
—
0
0
140
1142
1.24
1.64
2.0
1.9
—
—
—
0
0
11
49
2.25
1.63
1.2
1.1
—
—
—
0
0
81
619
1.32
1.60
4.2
4.6
2.4
2.7
mmol/l
0.36
61
431
22
128
1.72
1.60
1.7
2.4
—
—
—
0
0
267
2319
1.17
1.60
2.6
2.4
6.0
7.3
ug/l
0.76
236
2046
81
620
1.31
1.59
4.2
4.6
5.0
5.0
kpa
0.00
75
613
177
1485
1.20
1.58
1.2
1.2
137.6
146.3
iu/ml
0.09
48
541
80
612
1.32
1.57
1.2
1.2
—
—
—
0
0
82
630
1.31
1.57
1.6
1.7
8974.0
13882.8
e6/l
0.87
53
451
63
466
1.36
1.55
1.3
1.3
54.8
61.9
mmol/l
0.77
44
377
93
728
1.29
1.55
4.2
4.4
7.4
7.4
ph
0.41
75
612
57
415
1.38
1.55
1.3
1.2
309.6
276.2
u/ml
0.35
31
257
24
145
1.66
1.54
1.1
1.1
—
—
—
0
0
38
257
1.48
1.53
1.7
1.5
—
—
—
0
0
50
357
1.41
1.52
1.6
1.5
32.2
32.1
g/l
0.03
44
325
95
748
1.28
1.52
1.4
1.4
263.2
277.7
ug/g
0.29
62
446
36
241
1.50
1.52
1.4
1.5
27.0
29.7
%
0.18
24
151
7
27
2.60
1.51
2.0
1.5
—
—
—
0
0
132
1085
1.23
1.47
1.6
1.6
—
21.2
—
0
29
16
87
1.84
1.45
1.4
1.4
2.1
2.0
umol/l
0.14
16
80
37
253
1.47
1.43
1.4
1.4
—
—
—
0
0
69
526
1.32
1.42
4.0
3.2
8.1
7.5
mmol/l
0.53
69
510
85
667
1.28
1.42
1.3
1.3
—
15.3
—
0
14
27
173
1.57
1.40
1.6
1.2
1.7
1.3
u/ml
0.11
13
85
310
2754
1.14
1.39
2.2
2.3
116.5
140.9
ug/g
1.02
242
2184
578
5325
1.11
1.38
3.0
3.1
0.7
0.8
ug/l
0.93
397
3591
9
41
2.20
1.37
1.0
1.0
—
—
—
0
0
71
547
1.31
1.37
1.3
1.3
9.9
10.2
u/l
0.06
56
447
48
348
1.39
1.37
1.2
1.1
0.3
1.8
u/ml
1.97
19
143
58
434
1.34
1.36
2.1
3.5
1.4
1.3
%
0.08
42
335
70
540
1.30
1.34
2.4
2.7
—
—
—
0
0
0
39
0.00
1.33
0.0
1.2
—
105.6
—
0
27
85
674
1.27
1.32
2.9
3.2
24.4
24.9
mmol/l
0.42
79
586
23
144
1.60
1.32
2.5
2.1
154.8
160.7
ug/min
—
5
36
82
649
1.27
1.30
1.7
1.9
10.4
11.6
mg/l
0.86
77
590
45
326
1.39
1.30
1.7
1.4
2372.1
1565.0
e6/l
0.56
30
237
40
284
1.41
1.29
2.2
4.1
—
—
—
0
0
8
34
2.36
1.29
1.8
1.4
79.5
75.6
%
—
8
29
25
163
1.54
1.23
1.6
2.2
707.2
706.1
e6/l
—
10
68
23
147
1.57
1.23
1.8
1.7
—
—
—
0
0
805
7574
1.09
1.22
4.5
4.0
—
—
—
0
0
701
6558
1.09
1.22
4.6
4.1
0.0
0.0
estimate
1.08
248
2184
20
124
1.62
1.20
2.1
3.9
—
—
—
0
0
55
418
1.32
1.19
1.1
1.3
—
—
—
0
0
6
26
2.31
1.18
1.2
1.2
—
—
—
0
0
69
542
1.28
1.18
3.0
3.1
0.8
0.8
nmol/l
0.11
55
417
39
281
1.39
1.18
14.3
6.3
7.3
7.4
mmol/l
0.09
33
233
8
38
2.11
1.18
2.5
1.5
—
—
—
0
0
67
527
1.28
1.14
1.7
1.8
0.9
0.8
nmol/l
0.38
56
440
54
413
1.31
1.13
1.4
1.4
92.9
121.7
u/ml
1.60
15
75
187
1630
1.16
1.13
3.9
3.1
—
—
—
0
0
62
486
1.28
1.10
2.9
2.8
—
—
—
0
0
41
303
1.36
1.09
1.1
1.1
2.3
5.0
u/ml
1.36
20
146
14
81
1.73
1.09
1.5
1.4
4.0
3.2
mmol/l
0.38
14
72
21
136
1.55
1.08
1.1
1.0
—
—
—
0
0
68
543
1.26
1.05
1.4
1.3
—
—
—
0
0
190
1671
1.15
1.04
8.7
7.1
25.0
24.6
mmol/l
0.76
178
1555
125
1064
1.18
1.04
6.4
4.6
—
—
—
0
0
149
1287
1.17
1.04
4.1
3.5
—
—
—
0
0
18
114
1.58
1.02
2.1
4.1
—
—
—
0
0
130
1512
0.85
1.01
1.5
1.6
—
—
—
0
0
521
4855
1.09
1.00
1.9
1.8
1097.9
1170.9
nmol/l
0.94
373
3654
112
950
1.19
0.98
1.1
1.1
—
—
—
0
0
39
293
1.34
0.96
1.1
1.1
0.1
1.7
u/ml
1.97
18
125
963
9201
1.07
0.96
5.0
5.0
2.4
3.1
ug/l
2.49
849
8217
282
2558
1.11
0.95
1.7
1.6
—
—
—
0
0
77
632
1.22
0.95
1.5
1.2
6.7
3.3
u/ml
0.60
15
71
7
37
1.89
0.94
1.3
1.1
—
—
—
0
0
57
454
1.26
0.92
1.4
1.6
—
—
—
0
0
23
159
1.45
0.91
1.1
1.1
45.2
35.0
mmol/l
0.65
16
140
2459
24235
1.08
0.91
4.7
4.5
1.4
1.5
mmol/l
8.14
2248
22209
704
6667
1.07
0.90
1.4
1.4
—
—
—
0
0
25
176
1.42
0.90
1.1
1.2
—
—
—
0
0
78
647
1.21
0.89
4.6
4.4
—
—
—
0
0
2476
24415
1.08
0.88
4.8
4.5
4.5
4.6
mmol/l
4.04
2294
22521
18
265
0.68
0.87
1.2
1.2
—
—
—
0
0
139
1214
1.15
0.87
1.6
1.8
1.7
1.5
g/l
0.77
114
1063
19
129
1.48
0.83
1.1
1.1
—
—
—
0
0
110
949
1.17
0.82
1.7
2.0
23.3
21.6
s
0.64
103
839
36
275
1.31
0.82
1.6
1.5
—
—
—
0
0
125
1090
1.15
0.81
2.2
2.0
3.0
2.0
ug/l
0.30
109
966
12
73
1.65
0.81
2.6
1.5
—
—
—
0
0
66
545
1.22
0.80
4.5
3.5
21.8
28.2
mg/l
0.93
48
343
11
66
1.67
0.78
1.1
1.0
—
—
—
0
0
11
66
1.67
0.78
1.1
1.0
—
—
—
0
0
11
66
1.67
0.78
1.1
1.0
—
—
—
0
0
0
26
0.00
0.78
0.0
12.9
—
—
—
0
0
15
98
1.53
0.78
1.1
1.1
0.3
1.0
u/ml
—
6
33
65
540
1.21
0.76
1.3
1.4
16.8
28.1
e6/l
0.39
48
415
65
540
1.21
0.76
1.3
1.5
367.4
1335.6
e6/l
1.01
51
437
76
641
1.19
0.76
1.5
1.2
17.0
8.3
u/ml
0.32
16
115
2378
23452
1.07
0.76
4.2
4.0
1.4
1.3
mmol/l
3.08
2168
21338
5
25
2.00
0.72
6.4
5.5
—
—
—
0
0
5
25
2.00
0.72
3.2
2.8
—
—
—
0
0
67
562
1.20
0.72
2.5
2.7
31.8
34.7
umol/l
0.72
56
476
76
645
1.18
0.72
2.6
2.3
53.9
102.5
ug/min
1.41
53
397
30
229
1.31
0.71
1.1
1.1
—
—
—
0
0
16
109
1.47
0.70
1.1
1.2
—
—
—
0
0
170
1531
1.12
0.70
1.4
1.3
84.4
51.6
au/ml
—
7
66
12
77
1.56
0.68
2.0
2.5
—
—
—
0
0
28
213
1.32
0.68
1.0
1.1
0.9
4.1
u/ml
2.15
11
84
35
275
1.28
0.68
1.0
1.1
0.1
2.4
u/ml
—
6
64
18
127
1.42
0.68
1.1
1.0
—
—
—
0
0
179
1622
1.11
0.67
3.9
3.6
7.4
7.4
ph
0.20
36
205
68
576
1.18
0.67
2.5
3.3
1125.8
785.0
u/ml
0.13
63
531
41
506
0.81
0.66
1.4
1.7
—
—
—
0
0
51
421
1.22
0.66
1.5
1.4
—
—
—
0
0
69
587
1.18
0.65
2.5
2.2
—
—
—
0
0
14
95
1.48
0.64
2.6
2.3
—
—
—
0
0
27
207
1.31
0.63
2.3
2.1
1.4
1.9
u/field
0.35
14
84
18
246
0.73
0.63
1.4
1.4
—
—
—
0
0
15
104
1.44
0.62
2.0
2.2
—
—
—
0
0
14
96
1.46
0.61
1.1
1.0
0.5
0.5
u/ml
—
5
25
19
256
0.74
0.61
1.4
1.5
—
—
—
0
0
180
1644
1.10
0.60
3.9
3.6
5.2
5.2
kpa
0.10
171
1523
184
1688
1.10
0.57
2.6
2.4
34.8
24.9
au/ml
—
8
82
198
2147
0.92
0.56
3.6
3.4
—
—
—
0
0
5
87
0.57
0.56
10.2
6.8
26.1
24.9
mmol/l
—
5
78
52
439
1.19
0.56
1.2
1.2
23.7
41.2
u/l
1.03
46
378
6
38
1.58
0.54
1.8
1.2
—
—
—
0
0
146
1329
1.10
0.54
2.4
2.4
—
—
—
0
0
22
282
0.78
0.52
1.2
1.4
0.1
0.3
nmol/l
6.66
16
211
12
83
1.45
0.51
1.3
1.2
—
—
—
0
0
530
5077
1.05
0.50
1.3
1.2
1.6
1.5
u/ml
0.09
141
1339
572
5491
1.05
0.50
1.8
1.7
430.0
33223966.6
pmol/l
4.81
470
4554
19
247
0.77
0.50
1.5
1.4
—
—
—
0
0
74
839
0.88
0.49
7.2
6.5
1.4
1.3
mmol/l
0.12
67
735
23
180
1.28
0.49
1.3
1.1
—
—
—
0
0
38
316
1.21
0.49
1.3
1.2
—
—
—
0
0
192
1781
1.08
0.49
1.2
1.2
—
—
—
0
0
549
5271
1.05
0.48
4.6
4.1
1.0
1.0
kg/l
0.09
74
786
26
208
1.25
0.48
2.0
1.9
11.4
11.2
%
0.10
26
208
114
1256
0.90
0.48
1.4
1.5
—
—
—
0
0
50
581
0.86
0.47
1.3
1.3
126.2
217.5
miu/ml
2.36
20
253
12
85
1.41
0.46
1.7
1.4
24.5
25.0
%
0.02
12
78
38
320
1.19
0.44
1.1
1.1
—
—
—
0
0
38
320
1.19
0.44
1.1
1.1
—
—
—
0
0
26
211
1.23
0.43
2.5
2.2
489.5
625.6
ml
1.03
18
138
19
148
1.29
0.43
1.1
1.1
—
—
—
0
0
24
193
1.25
0.43
1.0
1.0
0.0
0.4
u/ml
—
6
49
175
1878
0.93
0.42
1.4
1.4
—
—
—
0
0
31
371
0.83
0.42
1.0
1.2
—
—
—
0
0
20
251
0.80
0.42
1.3
1.2
—
—
—
0
0
44
378
1.17
0.42
1.1
1.1
—
—
—
0
0
30
249
1.21
0.41
1.5
1.4
229372.1
84271.0
e6/l
0.28
22
174
42
361
1.17
0.40
6.4
6.7
12.5
12.0
mg/l
0.31
37
340
0
19
0.00
0.39
0.0
4.1
—
—
—
0
0
46
400
1.15
0.39
1.0
1.1
127.7
61.9
iu/ml
—
10
84
59
523
1.13
0.38
3.9
3.6
60.4
58.0
%
0.86
59
523
9
66
1.36
0.38
1.2
1.4
23.9
23.3
%
—
9
52
26
215
1.21
0.38
1.2
1.2
391.2
381.6
nmol/l
0.09
20
188
37
317
1.17
0.37
1.0
1.1
2.5
2.4
u/ml
0.07
13
135
225
2126
1.06
0.37
4.9
4.1
—
—
—
0
0
9
68
1.32
0.37
1.3
1.2
—
—
—
0
0
5
37
1.35
0.37
2.0
2.1
18.9
18.8
umol/l
—
5
37
82
745
1.10
0.36
1.0
1.1
—
—
—
0
0
175
1644
1.07
0.35
1.2
1.2
—
—
—
0
0
96
880
1.09
0.35
1.6
1.6
—
—
—
0
0
48
423
1.14
0.35
1.7
1.4
—
—
—
0
0
33
283
1.17
0.34
2.7
2.1
—
—
—
0
0
73
663
1.10
0.33
1.3
1.2
115.0
107.8
titre
—
6
50
143
1341
1.07
0.32
1.3
1.2
—
—
—
0
0
196
1858
1.06
0.31
1.9
2.2
11.1
12.6
nmol/l
1.95
172
1636
75
816
0.92
0.29
13.9
10.2
—
—
—
0
0
21
176
1.19
0.28
2.5
1.5
1.1
0.9
g/l
0.73
21
176
20
167
1.20
0.28
1.6
1.3
2214.4
1930.0
ml
—
7
30
47
523
0.90
0.28
2.0
2.1
—
—
—
0
0
41
365
1.12
0.27
4.8
5.3
352.4
356.3
umol/l
0.07
33
318
8
64
1.25
0.27
1.5
1.7
—
—
—
0
0
274
2634
1.04
0.27
4.2
4.3
—
—
—
0
0
25
215
1.16
0.26
1.5
1.5
—
—
—
0
0
9
73
1.23
0.25
1.7
1.6
—
—
—
0
0
37
330
1.12
0.25
1.1
1.3
—
—
—
0
0
51
559
0.91
0.24
1.9
2.0
—
—
—
0
0
48
436
1.10
0.24
1.4
1.5
—
—
—
0
0
52
567
0.92
0.23
1.9
2.0
—
—
—
0
0
30
267
1.12
0.21
2.0
3.4
55.2
56.1
%
0.06
19
169
78
730
1.07
0.21
1.2
1.2
—
—
—
0
0
0
12
0.00
0.21
0.0
1.7
—
13.1
—
0
12
5
43
1.16
0.21
3.0
5.3
—
—
—
0
0
34
306
1.11
0.21
1.2
1.6
59.4
61.1
%
0.09
23
192
28
249
1.13
0.20
1.1
1.2
—
—
—
0
0
52
563
0.92
0.20
1.9
2.0
—
—
—
0
0
9
112
0.80
0.20
1.3
1.8
3.7
8.7
nmol/l
—
9
94
97
918
1.06
0.19
2.9
3.2
0.5
0.3
g/l
0.60
46
368
34
375
0.91
0.19
1.3
1.2
6.5
5.0
u/ml
0.14
13
158
75
706
1.06
0.18
1.1
1.1
—
—
—
0
0
16
185
0.86
0.18
1.1
1.0
834.7
697.3
ng/l
0.49
11
118
123
1177
1.05
0.17
4.2
3.7
—
—
—
0
0
32
291
1.10
0.17
2.9
2.6
—
—
—
0
0
20
177
1.13
0.16
1.2
1.1
—
—
—
0
0
52
556
0.93
0.16
1.9
1.9
—
—
—
0
0
8
73
1.10
0.15
1.0
1.2
—
—
—
0
0
26
235
1.11
0.15
1.0
1.0
4.9
3.2
u/ml
—
8
87
6
77
0.78
0.15
1.7
1.7
—
—
—
0
0
15
131
1.15
0.14
1.1
1.2
—
—
—
0
0
10
118
0.85
0.14
6.3
13.4
—
—
—
0
0
15
132
1.14
0.13
2.3
2.8
—
—
—
0
0
20
180
1.11
0.13
2.0
2.3
—
—
—
0
0
11
94
1.17
0.13
2.3
1.6
—
—
—
0
0
55
521
1.06
0.12
1.6
2.1
6980.5
2918.4
u/l
0.41
22
214
17
152
1.12
0.12
1.1
1.4
4.3
5.1
ug/l
0.15
17
126
42
395
1.06
0.12
1.1
1.1
—
—
—
0
0
27
249
1.09
0.12
1.2
1.2
—
—
—
0
0
39
366
1.07
0.11
2.2
3.0
—
—
—
0
0
181
1767
1.03
0.11
1.3
1.3
—
—
—
0
0
104
1006
1.04
0.11
4.4
3.8
25.2
24.8
mmol/l
0.62
99
935
14
125
1.12
0.10
14.6
11.2
0.7
0.6
mmol/l
0.16
14
115
46
437
1.05
0.10
1.9
2.0
—
—
—
0
0
5
44
1.14
0.10
2.4
1.6
—
—
—
0
0
15
166
0.90
0.09
1.5
1.5
70.0
67.1
pmol/l
—
6
52
10
87
1.15
0.09
1.2
1.1
—
—
—
0
0
32
301
1.06
0.09
1.6
1.5
—
—
—
0
0
32
301
1.06
0.09
1.6
1.5
—
—
—
0
0
32
301
1.06
0.09
1.6
1.5
—
—
—
0
0
14
155
0.90
0.09
3.0
2.8
37.7
39.4
%
—
6
51
840
8336
1.01
0.09
3.3
2.9
—
—
—
0
0
6
56
1.07
0.08
2.7
1.9
—
—
—
0
0
24
257
0.93
0.08
2.5
2.3
—
—
—
0
0
33
312
1.06
0.08
1.1
1.3
—
—
nmol/l
—
0
0
21
226
0.93
0.08
2.7
2.0
—
1.5
—
0
9
17
185
0.92
0.08
1.1
1.0
371.0
311.5
ng/l
0.35
11
120
104
1068
0.97
0.08
2.0
1.7
—
—
—
0
0
7
64
1.09
0.08
1.1
1.0
—
—
—
0
0
30
283
1.06
0.08
1.2
1.3
21.2
28.2
u/l
0.73
25
231
56
581
0.96
0.07
1.3
1.2
—
—
—
0
0
8
75
1.07
0.07
2.1
2.2
—
—
—
0
0
8
77
1.04
0.07
1.1
1.1
—
—
—
0
0
10
112
0.89
0.07
1.0
1.2
—
—
—
0
0
7
83
0.84
0.07
1.3
1.3
—
—
—
0
0
10
89
1.12
0.06
1.1
1.1
—
—
—
0
0
10
89
1.12
0.06
1.2
1.1
1844.5
1600.6
miu/ml
—
10
89
10
89
1.12
0.06
2.0
1.8
24.5
110.7
ug/l
—
10
76
8
94
0.85
0.06
1.1
1.4
—
—
—
0
0
27
285
0.95
0.06
1.4
1.2
—
—
—
0
0
9
104
0.86
0.06
1.7
1.4
—
—
—
0
0
32
305
1.05
0.06
4.4
3.2
6.7
22.3
nmol/l
0.41
32
298
37
356
1.04
0.05
1.1
1.3
0.7
0.6
nmol/l
0.20
37
339
26
248
1.05
0.05
2.3
2.5
—
—
—
0
0
13
140
0.93
0.04
1.1
1.1
1.1
1.1
ratio
—
6
54
25
240
1.04
0.03
1.6
1.5
—
—
—
0
0
25
259
0.96
0.02
1.7
2.1
—
—
—
0
0
31
301
1.03
0.02
1.6
1.5
—
—
—
0
0
31
319
0.97
0.02
1.2
1.2
—
—
—
0
0
10
106
0.94
0.01
1.2
1.2
185.6
205.2
iu/ml
—
10
106
13
124
1.05
0.00
9.4
13.6
1039.5
823.5
nmol/l
0.83
13
119
24
234
1.03
0.00
1.8
1.8
—
—
—
0
0
13
129
1.01
0.00
2.1
1.7
—
—
—
0
0
14
139
1.01
0.00
1.1
1.3
138.2
139.1
nmol/l
0.03
14
139
20
199
1.01
0.00
1.1
1.0
—
—
—
0
0
13
126
1.03
0.00
1.3
1.2
195.2
350.8
u/l
0.76
13
119
16
164
0.98
0.00
2.2
1.6
—
—
—
0
0
37
366
1.01
0.00
1.4
1.3
—
—
—
0
0
28
278
1.01
0.00
1.2
1.1
—
—
—
0
0
7
72
0.97
0.00
1.3
1.4
—
—
—
0
0
9
90
1.00
0.00
1.3
1.1
—
—
—
0
0
6
61
0.98
0.00
1.0
1.2
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
7
70
1.00
0.00
1.3
1.6
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
5
59
0.85
0.00
1.4
1.1
14.8
16.6
umol/l
—
5
52
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
8
80
1.00
0.00
2.5
2.2
—
—
—
0
0
0
8
0.00
0.00
0.0
2.0
—
—
—
0
0
5
59
0.85
0.00
1.0
1.9
—
—
—
0
0
0
5
0.00
0.00
0.0
2.4
—
4.7
—
0
5
0
6
0.00
0.00
0.0
5.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.7
—
—
—
0
0
0
8
0.00
0.00
0.0
1.3
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.6
—
2984.0
—
0
5
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
0.00
0.0
1.9
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint CD2_BENIGN_PAROTID and mortality.

Females

Parameter HR [95% CI] p-value
CD2_BENIGN_PAROTID 1.19 [1.08, 1.32] < 0.001
Birth year 0.998 [0.99, 1.01] 0.646

During the follow-up period (1.1.1998 — 31.12.2019), 1511 out of 7825 females with CD2_BENIGN_PAROTID died.

Males

Parameter HR [95% CI] p-value
CD2_BENIGN_PAROTID 1.421 [1.28, 1.58] < 0.001
Birth year 0.983 [0.97, 0.99] < 0.001

During the follow-up period (1.1.1998 — 31.12.2019), 1822 out of 7379 males with CD2_BENIGN_PAROTID died.

Mortality risk

Mortality risk for people of age

years, who have CD2_BENIGN_PAROTID.

N-year risk Females Males
1 0.135% 0.232%
5 0.745% 1.402%
10 1.798% 3.64%
15 3.695% 6.904%
20 6.618% 11.678%

Relationships between endpoints

Index endpoint: CD2_BENIGN_PAROTID – Benign neoplasm: Parotid gland

GWS hits: 3

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
loading spinner Loading data