Benign neoplasm: salivary glands, exclude unknown (D119)

CD2_BENIGN_SALIVARY_KNOWN

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

2 out of 7 registries used, show all original rules.

3371

4. Check minimum number of events

None

3371

5. Include endpoints

None

3371

6. Filter based on genotype QC (FinnGen only)

3371

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy
C
First used in FinnGen datafreeze
DF9

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 19916 10324 9492
Only index persons 18679 9842 8837
Unadjusted period prevalence (%)
Whole population 0.28 0.30 0.27
Only index persons 0.35 0.36 0.34
Median age at first event (years)
Whole population 60.67 60.79 60.55
Only index persons 59.98 60.13 59.82

-FinnGen-

Key figures

All Female Male
Number of individuals 3371 1748 1623
Unadjusted period prevalence (%) 0.65 0.60 0.72
Median age at first event (years) 59.97 57.38 62.76

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
3024
Matched controls
30239
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
ELB40
NOMESCO Finland
Partial parotidectomy
1705.8
323.0
1488
17
D11.70
ICD-10 Finland
Gland sublingual
+∞
323.0
347
*
D11.0
ICD-10 Finland
Benign neoplasm: Parotid gland
+∞
323.0
2699
*
EP1AE
NOMESCO Finland
Neck ultrasound examination
12.9
323.0
732
729
R22.1
ICD-10 Finland
Localized swelling, mass and lump, neck
14.9
301.4
528
424
EL4AT
NOMESCO Finland
Salivary gland cytology with ultrasound guidance
313.3
256.2
257
9
ELB30
NOMESCO Finland
Excision of submandibular gland
104.7
220.9
241
25
ELB00
NOMESCO Finland
Excision or exploration of lesion of salivary gland
274.7
202.6
205
8
D37.00
ICD-10 Finland
Aryepiglottic fold marginal zone
97.3
181.7
200
22
ELB50
NOMESCO Finland
Total parotidectomy
317.2
177.0
178
6
EP1CG
NOMESCO Finland
Extensive MRI examination of soft tissue of neck with high intesity magnet
22.2
132.3
196
94
WX408
NOMESCO Finland
General anesthesy, balanced
2.8
130.7
1143
5399
EL3AE
NOMESCO Finland
Salivary gland ultrasound examination
32.8
122.1
162
52
C07.70
ICD-10 Finland
Malignant tumor of the superficial part of the parotid gland
175.3
113.2
118
7
XW1AT
NOMESCO Finland
Biopsy from other organ close to skin with ultrasound quidance
33.3
106.0
140
44
K11.2
ICD-10 Finland
Sialoadenitis
7.8
103.6
250
344
EP1DG
NOMESCO Finland
Very extensive examination of soft tissue of neck with high intesity magnet
20.5
72.2
109
55
R22.0
ICD-10 Finland
Localized swelling, mass and lump, head
5.9
70.5
207
371
ZXA05
NOMESCO Finland
Left side
2.1
60.8
915
5222
ZXA00
NOMESCO Finland
Right side
2.0
59.6
937
5434
R59.0
ICD-10 Finland
Localized enlarged lymph nodes
5.4
56.6
179
350
D11.9
ICD-10 Finland
Benign neoplasm: Major salivary gland, unspecified
96.8
52.0
57
6
WX402
NOMESCO Finland
General anaesthesia
2.3
50.5
570
2829
EP2AT
NOMESCO Finland
Neck soft tissue cytology with ultrasound guidance
23.2
45.8
66
29
D11.7
ICD-10 Finland
Benign neoplasm: Other major salivary glands
+∞
43.8
42
*
EL3AT
NOMESCO Finland
Salivary gland biopsy with ultrasound guidance
218.0
42.0
43
*
R22.9
ICD-10 Finland
Localized swelling, mass and lump, unspecified
2.9
40.2
261
951
PJD41
NOMESCO Finland
Excision of cervical lymph nodes
7.1
38.4
96
139
PJD81
NOMESCO Finland
Excision of lymph nodes from upper part of neck
11.7
38.0
71
62
K11.9
ICD-10 Finland
Disease of salivary gland, unspecified
12.7
36.7
66
53
C07.71
ICD-10 Finland
Malignant tumor in the deep part of the parotid gland
+∞
35.5
34
*
QX4AT
NOMESCO Finland
Ultrsound guided needle biopsy of skin
16.8
35.0
56
34
J01DB01
ATC
cefalexin; oral
1.7
34.2
2385
20666
ELB99
NOMESCO Finland
Other excision of salivary gland
121.4
33.7
36
*
EN1BD
NOMESCO Finland
Very extensive CT examination of mouth and soft tissues of neck
5.9
32.3
92
159
S04
ICPC
Lump/swelling localized
2.3
30.3
300
1376
N02BE01
ATC
paracetamol; systemic, rectal
1.7
29.5
2522
22473
PJ3AT
NOMESCO Finland
Cytology of lymphnode with ultrasound guidance
6.3
29.0
78
126
WX110
NOMESCO Finland
Local anesthesy
1.6
28.9
1937
16143
DWD00
NOMESCO Finland
Reoperation for superficial heamorrhage in surgery of ear, nose and larynx
64.6
27.9
32
5
8550/3-C07.9
ICD-O-3
Acinar cell carcinoma of parotid gland
101.0
27.7
30
*
TDW99
NOMESCO Finland
Other minor procedure in surgery of ear, nose and larynx
3.3
25.7
133
413
L04.0
ICD-10 Finland
Acute lymphadenitis of face, head and neck
8.0
25.4
58
74
BA3AT
NOMESCO Finland
Cytology of thyroid with ultrasound quidance
4.9
25.3
84
175
PJD91
NOMESCO Finland
Excision of lymph nodes in neck, 1 to 2 areas in total
70.5
24.8
28
*
S18
ICPC
Laceration/cut
1.5
24.4
1201
9184
2102A
ICD-9 Finland
Benign neoplasm of lip, oral cavity and pharynx, Major salivary glands
23.8
23.5
33
14
J44.8
ICD-10 Finland
Other specified chronic obstructive pulmonary disease
2.0
21.9
313
1676
C08.89
ICD-10 Finland
Malignant overall tumor the large salivary glands anna or unspecified histology
221.5
21.6
22
*
8430/3-C07.9
ICD-O-3
Mucoepidermoid carcinoma of parotid gland
115.9
21.6
23
*
EP1CM
NOMESCO Finland
Extensive MRI examination of soft tissue of neck with 3 Tesla magnet
19.6
20.8
31
16
Z71.2
ICD-10 Finland
Person consulting for explanation of investigation findings
1.6
20.7
648
4424
4405
FHL
Partial removal of the parotid gland
24.7
19.5
27
11
UDQ12
NOMESCO Finland
Flexible laryngoscopy
2.3
19.0
179
800
R03BB04
ATC
tiotropium bromide; inhalant
1.8
17.9
303
1723
K11.3
ICD-10 Finland
Abscess of salivary gland
36.9
17.6
22
6
PJD71
NOMESCO Finland
Extended sparing excision of cervical lymph nodes
8.4
17.4
38
46
YA1BD
NOMESCO Finland
Extensive CT examination of head and neck for dose design of radiotherapy
6.3
17.1
45
72
R59.1
ICD-10 Finland
Generalized enlarged lymph nodes
4.4
17.1
62
144
C08.94
ICD-10 Finland
Mucoepidermoid carcinoma of an unspecified large salivary gland
+∞
16.7
16
*
D11.71
ICD-10 Finland
Gland submandibular
+∞
16.7
16
*
EN1AD
NOMESCO Finland
CT examination of mouth and soft tissues of neck
5.6
16.6
48
87
K11.88
ICD-10 Finland
Other diseases of salivary glands
16.4
16.5
26
16
TQA05
NOMESCO Finland
Puncture of skin of head or neck
40.3
16.3
20
5
QAE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in head or neck
1.9
16.1
250
1380
C08.09
ICD-10 Finland
Malignant tumor of the submandibular or submaxillary gland, other or unspecified histology
85.5
15.6
17
*
C82.1
ICD-10 Finland
Follicular lymphoma grade II
6.9
15.4
38
56
TPJ05
NOMESCO Finland
Needle biopsy of lymph node
38.2
15.4
19
5
Q18.0
ICD-10 Finland
Sinus, fistula and cyst of branchial cleft
9.8
15.2
30
31
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
1.8
14.8
290
1724
EP1BG
NOMESCO Finland
MRI examination of soft tissue of neck with high intesity magnet
9.2
14.7
30
33
EP1AE
SPAT
NA
4.8
14.6
48
101
WX404
NOMESCO Finland
Intravenous generell anesthesy
1.5
14.6
544
3833
C08.99
ICD-10 Finland
Malignant tumor of unspecified large salivary gland, other or unspecified histology
80.5
14.6
16
*
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.4
14.5
1042
8335
WZC00
NOMESCO Finland
Planning of intervention or health care consultation
1.4
14.4
860
6658
J01DA01
ATC
[U] cefalexin; systemic
1.4
14.4
1710
14834
CBK11
NOMESCO Finland
Operation for lagophtalmus with implant
27.3
14.3
19
7
SPAT1153
SPAT
Removal of sutures
1.4
13.9
869
6778
C83.80
ICD-10 Finland
B-cell lymphoma in marginal zone
8.2
13.8
30
37
TEL00
NOMESCO Finland
Needle biopsy of salivary gland
140.6
13.5
14
*
B02
ICPC
Lymph gland(s) enlarged/painful
6.2
13.3
35
57
WF003
NOMESCO Finland
Adjuvant radiotherapy
2.4
13.1
108
455
JN4KR
NOMESCO Finland
Whole body very extensive metabolic PET with CT
5.7
12.5
35
62
C08.90
ICD-10 Finland
Malignant tumor in unspecified large salivary gland without histology
+∞
12.5
12
*
ZXC99
NOMESCO Finland
Other special technic in surgery
17.4
12.5
19
11
UDC00
NOMESCO Finland
Ear microscopy
1.8
12.2
201
1133
EP1DM
NOMESCO Finland
Very extensive MRI examination of soft tissue of neck with 3 Tesla magnet
30.1
11.6
15
5
ELW99
NOMESCO Finland
Other operation on salivary gland
65.2
11.6
13
*
9699/3-C07.9
ICD-O-3
Marginal zone B-cell lymphoma, NOS, of parotid gland
+∞
11.5
11
*
Z72.0
ICD-10 Finland
Tobacco use
2.8
11.4
75
277
21020
ICD-8 Finland
Benign neoplasm of buccal cavity and pharynx, Salivary gland
10.1
11.0
21
21
WZC20
NOMESCO Finland
Multidisciplinary treatment meeting
2.0
10.9
143
740
XX3DW
NOMESCO Finland
Time consuming IT work
1.6
10.7
269
1720
K11.4
ICD-10 Finland
Fistula of salivary gland
60.2
10.6
12
*
UDH02
NOMESCO Finland
Rhinopharyngoscopy
1.8
10.6
170
951
C77.0
ICD-10 Finland
Secondary and unspecified malignant neoplasm: Lymph nodes of head, face and neck
5.7
10.5
29
51
ELA30
NOMESCO Finland
Biopsy of salivary gland
14.2
10.5
17
12
J44.1
ICD-10 Finland
Chronic obstructive pulmonary disease with acute exacerbation, unspecified
2.3
10.4
91
397
C08.00
ICD-10 Finland
Malignant tumor of submandibular or submaxillary gland, not histology
110.4
10.4
11
*
C85.9
ICD-10 Finland
Non-Hodgkin lymphoma, unspecified
4.8
10.4
33
69
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.3
10.3
1156
9760
K11.5
ICD-10 Finland
Sialolithiasis
3.2
10.2
51
159
M01AE03
ATC
ketoprofen; systemic, rectal
1.3
10.1
1007
8359
YA1CD
NOMESCO Finland
Very extensive CT examination of head and neck for dose design of radiotherapy
10.1
10.0
19
19
EWE00
NOMESCO Finland
Reoperation for deep haemorrhage in surgery of teeth, jaws, mouth and pharynx
14.6
10.0
16
11
E04.2
ICD-10 Finland
Nontoxic multinodular goitre
2.1
9.9
103
488
J01FF01
ATC
clindamycin; systemic
1.4
9.8
689
5418
EP1AT
NOMESCO Finland
Punction of soft tissue of neck with ultrasound guidance
55.2
9.6
11
*
A02BC02
ATC
pantoprazole; systemic
1.3
9.6
1737
15543
D44.0
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Thyroid gland
3.1
9.6
50
162
C73.91
ICD-10 Finland
Papillary carcinoma of the thyroid gland (thyroid gland)
3.3
9.5
46
141
C07
ICD-10 Finland
Malignant neoplasm of parotid gland
100.3
9.4
10
*
AAH50
NOMESCO Finland
Cranial nerve anastomosis
30.1
9.4
12
*
8500/3-C07.9
ICD-O-3
Infiltrating duct carcinoma, NOS, of parotid gland
+∞
9.4
9
*
J44.0
ICD-10 Finland
Chronic obstructive pulmonary disease with acute lower respiratory infection
1.9
9.4
125
656
NAR20
NOMESCO Finland
Complete excision of soft tissue tumour of spine, unspecified
8.7
9.3
19
22
8260/3-C73.9
ICD-O-3
Papillary adenocarcinoma, NOS, of thyroid gland
3.4
9.2
42
124
M35.0
ICD-10 Finland
Sicca syndrome [Sjögren]
2.9
9.2
54
190
R4110
NOMESCO Finland
Physiotherapy
1.3
9.0
674
5346
SAA03
NOMESCO Finland
Extended examination of mouth
1.3
8.9
909
7539
EP3AT
NOMESCO Finland
Neck soft tissue biopsy with ultrasound guidance
24.1
8.9
12
5
J44.9
ICD-10 Finland
Chronic obstructive pulmonary disease, unspecified
1.9
8.8
119
627
R91
ICD-10 Finland
Abnormal findings on diagnostic imaging of lung
1.6
8.8
261
1736
N02AX02
ATC
tramadol; systemic, rectal
1.3
8.8
1093
9296
C82.01
ICD-10 Finland
Follicular nodular lymphoma, grade I
6.3
8.8
22
35
N07BA03
ATC
varenicline; oral
1.9
8.7
122
653
WZC10
NOMESCO Finland
Extensive specialist consultion with written report
1.9
8.6
119
630
QAA99
NOMESCO Finland
Other local destruction of skin of head or neck
7.6
8.6
19
25
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.3
8.5
1170
10061
J01AA02
ATC
doxycycline; systemic
1.3
8.4
2136
19760
A07AA02
ATC
nystatin; oral
1.7
8.4
158
932
QAA05
NOMESCO Finland
Incision for biopsy of skin of head or neck
2.4
8.4
68
288
D21.0
ICD-10 Finland
Benign neoplasm: Connective and other soft tissue of head, face and neck
6.7
8.3
20
30
XW1XT
NOMESCO Finland
Biopsy from other organ close to skin with other quidance
+∞
8.3
8
*
8200/3-C07.9
ICD-O-3
Adenoid cystic carcinoma of parotid gland
+∞
8.3
8
*
I70.2
ICD-10 Finland
Atherosclerosis of arteries of extremities
1.6
8.3
231
1518
203
Kela drug reimbursment
Chronic asthma and similar chronic obstructive pulmonary diseases
1.4
8.2
457
3452
GD1BD
NOMESCO Finland
Thorax extensive CT-examination
1.8
8.2
140
801
D17.0
ICD-10 Finland
Benign lipomatous neoplasm of skin and subcutaneous tissue of head, face and neck
2.7
8.2
52
192
D14.0
ICD-10 Finland
Benign neoplasm: Middle ear, nasal cavity and accessory sinuses
3.7
8.1
33
89
D37.09
ICD-10 Finland
Lip, oral cavity and pharynx
17.2
8.1
12
7
K11
ICD-10 Finland
Diseases of salivary glands
17.2
8.1
12
7
K04.5
ICD-10 Finland
Chronic apical periodontitis
1.3
8.0
605
4794
JN4JR
NOMESCO Finland
Whole body extensive metabolic PET with CT
4.1
8.0
29
71
UGC12
NOMESCO Finland
Flexible bronchoscopy
1.6
7.9
198
1267
R03AC02
ATC
salbutamol; inhalant
1.2
7.9
1297
11365
Z01.8
ICD-10 Finland
Other specified special examinations
1.3
7.8
526
4097
J01CE02
ATC
phenoxymethylpenicillin; oral
1.2
7.8
1770
16075
P01AB01
ATC
metronidazole; oral, rectal
1.3
7.8
966
8185
H02AB06
ATC
prednisolone; systemic
1.2
7.7
1194
10383
K11.1
ICD-10 Finland
Hypertrophy of salivary gland
18.4
7.6
11
6
TQW40
NOMESCO Finland
Remowal of suture of skin
1.6
7.5
171
1067
8070/3-C07.9
ICD-O-3
Squamous cell carcinoma, NOS, of parotid gland
80.3
7.4
8
*
JN4BD
NOMESCO Finland
Extensive body CT
1.5
7.4
284
2004
N39.0
ICD-10 Finland
Urinary tract infection, site not specified
1.4
7.3
315
2269
M01AE01
ATC
ibuprofen; systemic, rectal
1.3
7.3
2456
23262
8147/3-C07.9
ICD-O-3
Basal cell adenocarcinoma of parotid gland
+∞
7.3
7
*
8941/3-C07.9
ICD-O-3
Carcinoma ex pleomorphic adenoma of parotid gland
+∞
7.3
7
*
C08.92
ICD-10 Finland
Coastal adenocarcinoma of unspecified salivary gland
+∞
7.3
7
*
ELB70
NOMESCO Finland
Excision of parotid gland neoplasm or other lesion extending into parapharyngeal space
+∞
7.3
7
*
L04.9
ICD-10 Finland
Acute lymphadenitis, unspecified
10.9
7.3
13
12
4404
FHL
Complete removal of the parotid gland
20.1
7.1
10
5
PJA10
NOMESCO Finland
Exploration of lymph nodes
2.9
7.1
39
134
YA1AD
NOMESCO Finland
CT examination of head and neck for dose design of radiotherapy
3.6
7.0
29
80
R52.9
ICD-10 Finland
Pain, unspecified
1.6
7.0
193
1262
130
Kela drug reimbursment
Malignant tumour
1.5
7.0
209
1397
R03AL06
ATC
olodaterol and tiotropium bromide; inhalant
2.5
6.8
49
197
E11.9
ICD-10 Finland
Type 2 diabetes mellitus, without complications
1.3
6.8
587
4738
J44
ICD-10 Finland
Other chronic obstructive pulmonary disease
2.3
6.8
57
247
K05.30
ICD-10 Finland
Periodontitis complex
1.4
6.7
298
2164
EBA00
NOMESCO Finland
Extraction of tooth
1.3
6.6
766
6413
504
Kela drug reimbursment
Conditions requiring daily forced enteral nutrition
3.0
6.6
35
118
L28
ICPC
Limited function/disability (L)
1.4
6.6
374
2834
117
Kela drug reimbursment
Leukaemia and other malignant diseases of the blood and bone marrow, and malignant diseases of the lymphatic tissue
1.8
6.5
108
617
QAE99
NOMESCO Finland
Other excision or repair surgery of skin and subcutaneous tissue in head and neck
2.2
6.5
61
281
C08.02
ICD-10 Finland
Cystic adenocarcinoma of the submandibular or submaxillary glands
70.0
6.4
7
*
D33.37
ICD-10 Finland
Another benign tumor of the cranial nerves
70.0
6.4
7
*
8200/3-C08.0
ICD-O-3
Adenoid cystic carcinoma of submandibular gland
70.0
6.4
7
*
ELB60
NOMESCO Finland
Radical parotidectomy sacrificing the facial nerve
70.0
6.4
7
*
G51.0
ICD-10 Finland
Bell palsy
2.1
6.4
65
307
R02
ICPC
Shortness of breath/dyspnoea
1.4
6.4
277
2003
DEB00
NOMESCO Finland
Cortical mastoidectomy
14.3
6.4
10
7
N02AA05
ATC
oxycodone; systemic
1.4
6.3
342
2572
A02BC01
ATC
omeprazole; systemic
1.3
6.3
668
5526
WX707
NOMESCO Finland
Fiberoscopic intubation
5.5
6.3
17
31
D14.1
ICD-10 Finland
Benign neoplasm: Larynx
3.7
6.3
25
68
C08.91
ICD-10 Finland
Adenocarcinoma of mixed cell type in unspecified large salivary gland
+∞
6.3
6
*
8502/3-C07.9
ICD-O-3
Secretory carcinoma of parotid gland
+∞
6.3
6
*
K11.80
ICD-10 Finland
Benign lymphoepithelial lesion of salivary gland
+∞
6.3
6
*
8430/3-C08.0
ICD-O-3
Mucoepidermoid carcinoma of submandibular gland
+∞
6.3
6
*
8562/3-C07.9
ICD-O-3
Epithelial-myoepithelial carcinoma of parotid gland
+∞
6.3
6
*
8140/3-C07.9
ICD-O-3
Adenocarcinoma, NOS, of parotid gland
+∞
6.3
6
*
K11.0
ICD-10 Finland
Atrophy of salivary gland
26.7
6.2
8
*
ZZK00
NOMESCO Finland
Graft of nerve
26.7
6.2
8
*
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
1.2
6.2
1023
8897
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.3
6.1
697
5813
N05BA01
ATC
diazepam; systemic, rectal
1.4
6.1
301
2226
K05.31
ICD-10 Finland
Periodontitis pronounced
1.5
6.1
233
1643
C03CA01
ATC
furosemide; systemic
1.3
6.1
713
5967
N30.0
ICD-10 Finland
Acute cystitis
1.4
6.1
295
2176
L72.1
ICD-10 Finland
Trichilemmal cyst
1.6
6.0
145
919
J45.9
ICD-10 Finland
Asthma, unspecified
1.3
6.0
397
3081

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
804
663
15.61
307.65
1.4
1.2
—
—
—
0
0
573
2511
2.54
80.69
1.5
1.4
—
—
—
0
0
698
3726
2.10
60.13
1.3
1.3
—
—
—
0
0
1611
11375
1.80
58.87
2.3
2.1
—
—
—
0
0
1667
13203
1.52
30.38
6.3
5.9
57.7
57.6
%
0.11
1543
12347
1742
13964
1.51
29.72
6.2
5.8
0.0
0.0
e9/l
0.40
1494
12053
1648
13091
1.51
29.15
6.6
6.3
8.9
8.7
%
1.24
1526
12253
1730
13899
1.50
28.84
6.2
5.7
0.6
0.6
e9/l
1.34
1480
11993
1783
14430
1.50
28.57
6.5
6.0
0.2
0.2
e9/l
0.14
1555
12626
1600
12674
1.50
28.42
6.5
6.1
0.7
0.7
%
0.23
1483
11825
1637
13029
1.50
28.40
6.5
6.0
2.9
2.9
%
0.10
1510
12138
1674
13400
1.50
28.14
6.5
6.1
27.1
27.4
%
0.50
1546
12473
1763
14270
1.49
28.00
6.3
5.8
1.9
1.9
e9/l
0.45
1545
12536
1957
16196
1.50
27.74
9.8
9.0
4.2
4.2
e9/l
0.65
1713
14136
517
3335
1.65
22.15
1.8
1.8
—
—
—
0
0
1620
13306
1.42
21.40
4.2
4.1
—
—
—
0
0
1718
14336
1.40
20.29
7.7
6.9
1.2
1.2
mmol/l
0.04
1468
12045
1150
9031
1.41
18.90
2.5
2.5
—
—
—
0
0
1950
16758
1.39
18.60
6.0
4.8
6.8
6.8
mmol/l
0.29
1846
15759
1247
9989
1.39
18.04
4.2
3.7
91.3
102.6
e6/l
0.13
872
7169
1565
13041
1.37
17.67
7.0
6.1
1.2
1.2
mmol/l
0.20
1438
11788
2958
27594
1.59
16.87
18.2
15.0
24.6
24.5
mg/l
0.06
2462
22090
1199
9632
1.38
16.71
6.3
5.8
—
—
—
0
0
1479
12286
1.36
16.69
11.1
9.7
0.0
0.0
e9/l
0.76
1215
10059
935
7214
1.41
16.53
4.7
4.0
88.5
89.2
%
0.38
926
7029
77
271
2.88
16.37
1.4
1.2
—
—
—
0
0
1077
8538
1.38
16.14
4.4
4.1
7.4
7.4
ph
1.38
202
1640
2426
21847
1.39
16.04
8.6
7.7
79.5
78.8
u/l
0.28
2301
20602
1003
7882
1.39
15.77
3.5
3.2
0.3
0.5
e6/l
2.53
737
5996
625
4518
1.47
15.63
3.5
3.0
2.3
2.3
e6/l
0.06
346
2486
1081
8620
1.37
15.48
3.7
3.3
45.0
99.8
e6/l
1.92
809
6673
973
7653
1.38
15.09
3.4
3.1
—
—
—
0
0
1479
12419
1.34
14.99
5.1
4.9
35.2
35.3
g/l
0.27
1366
11547
98
408
2.44
14.97
2.2
1.6
1.1
0.8
g/l
0.56
75
314
54
165
3.31
14.62
6.4
6.6
—
—
—
0
0
657
4852
1.44
14.58
3.3
2.8
1.6
1.1
e6/l
0.36
378
2804
2729
25217
1.43
14.48
5.3
4.7
2.7
2.1
mu/l
0.35
2500
22971
2303
20699
1.36
14.45
4.7
4.1
13.3
12.6
mm/h
1.09
2140
19141
382
2540
1.57
14.10
1.6
1.5
—
—
—
0
0
2072
18385
1.33
13.84
5.0
4.6
3782.9
1448.2
e6/l
0.36
34
273
2149
19206
1.33
13.43
4.8
4.4
—
—
—
0
0
562
4090
1.45
13.39
2.0
2.1
—
—
—
0
0
1722
14939
1.31
13.24
6.9
6.3
11.1
11.6
umol/l
1.13
1662
14185
882
6956
1.36
13.11
2.5
2.4
—
—
—
0
0
65
244
2.70
12.33
5.6
5.0
97.4
48.7
u/ml
0.30
20
67
2309
20971
1.32
12.16
4.4
4.0
15.1
14.8
pmol/l
4.32
2088
18991
1393
11844
1.30
12.00
11.2
9.7
1.3
1.3
inr
0.49
407
3394
3030
28790
1.52
11.84
20.7
17.5
4.0
4.0
mmol/l
0.56
2965
28022
885
7078
1.34
11.79
7.4
6.6
—
—
—
0
0
1164
9682
1.31
11.74
3.8
3.4
2.4
2.4
mmol/l
0.25
1028
8428
3023
28722
1.51
11.68
20.7
17.3
139.7
139.7
mmol/l
0.21
2964
27996
760
6024
1.34
10.59
5.0
4.5
—
—
—
0
0
499
3703
1.41
10.50
8.7
7.0
104.6
104.3
mmol/l
0.80
482
3615
2455
22673
1.30
10.32
22.0
18.1
13.9
13.7
%
2.24
2409
22155
970
7996
1.30
10.14
4.8
4.4
—
—
—
0
0
674
5311
1.34
9.68
3.4
3.1
2.5
2.5
mmol/l
0.14
595
4688
2172
19855
1.26
9.30
4.3
3.9
—
—
—
0
0
605
4738
1.34
9.00
3.5
3.3
0.8
0.8
mmol/l
1.16
568
4424
235
1557
1.55
8.79
11.9
9.8
24.5
24.3
mmol/l
0.25
218
1464
501
3831
1.36
8.70
5.5
5.9
1.0
1.0
mmol/l
1.27
459
3559
1346
11719
1.25
8.61
2.1
2.0
93.2
94.8
pmol/l
0.55
742
6108
59
254
2.35
8.53
1.6
1.4
7.2
6.9
g/l
0.19
41
177
59
254
2.35
8.53
1.6
1.4
0.4
0.4
g/l
0.46
41
177
59
254
2.35
8.53
1.6
1.4
2.8
2.9
g/l
0.22
41
177
697
5608
1.31
8.52
3.0
2.8
553.0
549.3
mosm/kgh2o
0.16
582
4777
1531
13549
1.24
8.36
5.6
5.0
0.0
0.0
estimate
0.50
288
2569
3056
29374
1.43
8.32
21.2
17.5
78.7
78.9
umol/l
0.17
3056
29362
3059
29417
1.43
8.21
12.1
10.7
25.6
26.3
u/l
1.29
2956
28353
3152
30488
1.52
8.20
26.2
22.0
248.9
248.4
e9/l
0.16
3074
29691
441
3335
1.37
8.20
2.5
2.5
1.8
1.8
%
0.17
389
2954
334
2412
1.43
8.14
10.5
8.6
—
—
—
0
0
3153
30506
1.52
8.12
26.2
22.0
6.9
6.8
e9/l
4.16
3063
29607
1313
11458
1.24
8.07
2.4
2.2
77.1
77.9
nmol/l
0.47
1177
10218
3152
30501
1.51
8.04
26.1
22.0
4.5
4.5
e12/l
0.05
3060
29610
58
255
2.30
8.01
1.6
1.4
—
—
—
0
0
450
3428
1.36
7.98
9.3
7.5
5.2
5.1
kpa
1.50
429
3269
450
3428
1.36
7.98
9.3
7.5
12.4
12.2
kpa
0.40
428
3267
3152
30507
1.51
7.96
26.3
22.1
134.9
135.1
g/l
0.37
3113
30044
3151
30497
1.51
7.94
26.1
21.9
91.4
91.3
fl
0.92
3107
30031
296
2101
1.45
7.92
2.9
2.8
10.8
10.6
g/l
0.44
273
1907
737
6029
1.28
7.87
2.6
2.6
4.5
5.3
e6/l
1.49
621
5303
3150
30498
1.50
7.78
26.1
21.9
30.4
30.4
pg
0.00
3107
30028
447
3417
1.36
7.74
9.4
7.5
1.2
1.1
mmol/l
0.18
351
2671
1023
8716
1.25
7.74
2.3
2.2
177.1
237.5
u/l
1.74
961
8171
1540
13720
1.23
7.64
4.2
3.7
0.0
0.0
estimate
1.34
280
2478
1520
13527
1.23
7.61
4.1
3.7
0.0
0.0
estimate
0.00
281
2523
298
2147
1.43
7.36
4.1
4.1
1.2
0.4
%
0.33
64
544
313
2289
1.41
7.11
4.1
4.1
0.2
0.1
%
0.56
79
653
352
2630
1.38
7.03
2.6
2.4
36.7
56.4
u/l
0.55
306
2265
237
1659
1.46
6.84
1.7
1.9
1.3
1.4
g/l
0.56
215
1503
993
8527
1.23
6.83
3.1
3.1
1579.8
1503.9
ng/l
0.15
868
7317
401
3074
1.35
6.80
10.0
7.9
95.3
95.6
%
0.30
392
2958
144
906
1.62
6.78
2.4
3.5
1.4
2.3
ratio
0.72
15
73
324
2406
1.38
6.72
4.0
4.0
1.3
0.9
%
1.19
86
704
2975
28626
1.33
6.64
16.0
14.1
—
—
—
0
0
354
2681
1.36
6.50
3.8
3.7
2.1
2.0
mmol/l
0.21
289
2161
1197
10518
1.21
6.49
3.7
3.5
—
5.8
—
0
7
281
2057
1.40
6.36
2.0
2.5
—
—
—
0
0
339
2561
1.36
6.32
9.3
7.2
1.3
1.4
mmol/l
0.46
329
2471
799
6751
1.24
6.31
1.6
1.6
20.3
20.6
nmol/l
0.15
691
5763
354
2694
1.35
6.30
3.8
3.7
6.0
5.8
kpa
2.75
348
2608
116
706
1.67
6.25
2.1
3.7
—
—
—
0
0
145
934
1.58
6.21
2.4
3.6
33.8
68.7
mg/l
1.48
115
758
145
935
1.58
6.19
2.4
3.5
65.8
121.8
mg/l
0.43
114
757
228
1619
1.44
6.13
3.5
3.3
4.3
4.4
pmol/l
1.69
208
1424
348
2661
1.34
6.00
7.4
7.3
9.8
10.2
mmol/l
0.49
333
2530
979
8486
1.22
6.00
3.8
3.2
—
—
—
0
0
764
6468
1.23
5.87
3.8
3.7
—
—
—
0
0
2698
25761
1.24
5.62
6.7
5.9
40.5
40.1
mmol/mol
1.32
2484
23776
674
5655
1.24
5.61
4.0
3.8
762.6
566.8
ng/l
0.28
553
4515
23
77
3.00
5.52
1.0
1.1
—
—
—
0
0
237
1728
1.40
5.51
8.8
7.4
24.9
24.9
mmol/l
0.06
231
1719
355
2764
1.32
5.41
2.5
2.2
0.2
0.2
g/l
1.20
331
2577
488
3966
1.27
5.35
1.2
1.2
—
—
—
0
0
152
1028
1.50
5.27
2.2
2.3
315.3
699.2
ug/l
1.11
144
971
246
1822
1.38
5.22
1.3
1.4
—
—
—
0
0
289
2196
1.35
5.21
3.8
3.8
1.1
0.6
%
1.08
57
505
1037
9139
1.19
5.19
4.2
4.0
8.2
9.3
mg/mmol
0.37
690
5772
321
2479
1.33
5.19
2.2
2.7
66.7
66.4
g/l
0.26
294
2269
835
7218
1.21
5.14
2.2
2.2
3.0
3.0
mg/l
0.01
700
6157
157
1076
1.48
5.12
1.9
2.5
10.2
10.3
g/l
0.09
136
924
1285
11554
1.18
5.07
3.0
2.8
134.0
138.8
ug/l
0.23
1179
10652
448
3631
1.27
5.02
1.4
1.3
646.9
535.8
titre
0.52
110
768
63
345
1.84
4.97
1.3
1.3
—
—
—
0
0
127
843
1.53
4.84
3.3
3.4
—
—
—
0
0
322
2514
1.31
4.82
2.6
2.6
73.6
70.1
e9/l
0.74
246
1922
870
7590
1.20
4.81
2.6
2.7
6312.5
5250.4
umol/l
0.24
750
6574
286
2201
1.33
4.75
3.6
3.9
90.3
92.9
ng/l
0.18
242
1895
35
157
2.24
4.75
1.9
2.1
—
—
—
0
0
716
6143
1.21
4.72
1.7
1.8
1.5
1.3
mg/l
0.84
547
4714
357
2846
1.28
4.57
10.9
8.4
120.7
121.7
g/l
0.38
348
2743
284
2197
1.32
4.55
3.3
2.9
4.6
4.6
kpa
0.01
277
2121
1223
11037
1.17
4.47
4.1
3.7
37.1
95.0
ng/l
0.80
861
7806
187
1363
1.39
4.41
3.6
3.9
24.3
24.2
mmol/l
0.29
166
1218
1010
8989
1.18
4.37
2.7
2.6
52.9
57.8
u/l
3.14
940
8300
595
5050
1.22
4.36
1.5
1.5
2.6
2.5
g/l
0.30
352
3082
977
8681
1.18
4.30
3.3
3.3
521.3
311.8
mg/l
0.60
646
5487
131
902
1.47
4.23
2.0
2.3
38.2
37.7
g/l
0.45
112
786
83
518
1.62
4.17
1.3
1.6
—
—
—
0
0
349
2810
1.27
4.14
1.5
1.6
—
—
—
0
0
1013
9053
1.17
4.12
3.3
3.2
7.4
7.5
mmol/l
0.14
843
7587
33
154
2.15
4.11
1.4
1.6
—
—
—
0
0
530
4473
1.22
4.10
2.1
2.0
30.3
29.8
s
1.24
519
4333
28
123
2.29
4.03
1.6
1.2
—
—
—
0
0
531
4491
1.22
4.02
2.5
2.5
12.7
12.9
umol/l
0.32
487
4178
495
4164
1.22
3.96
2.5
2.5
2.3
2.3
g/l
0.43
456
3865
96
629
1.54
3.95
2.2
2.1
127.4
128.8
g/l
0.20
75
453
470
3938
1.22
3.91
1.6
1.7
—
—
—
0
0
403
3331
1.24
3.81
1.6
1.4
—
—
—
0
0
168
1235
1.38
3.81
1.2
1.2
—
—
—
0
0
461
3871
1.22
3.75
25.4
25.4
1.3
1.3
inr
0.52
61
545
106
723
1.48
3.64
3.3
2.9
1.5
1.6
mg/l
0.18
94
659
32
156
2.06
3.61
1.6
2.7
7.4
7.4
ph
—
9
53
382
3166
1.23
3.53
1.3
1.3
—
—
—
0
0
14
46
3.05
3.52
1.4
1.2
—
—
—
0
0
2576
24792
1.17
3.49
19.9
16.0
39.6
39.6
%
0.05
1827
17208
386
3213
1.23
3.43
3.4
2.7
8.9
8.6
umol/l
0.09
335
2809
460
3904
1.21
3.36
2.6
2.6
21.1
22.8
%
2.18
400
3338
92
622
1.49
3.32
2.6
2.4
15.7
16.2
%
0.44
51
304
1902
17954
1.14
3.32
3.4
3.1
53.3
51.3
u/l
0.36
1776
16626
400
3354
1.22
3.31
1.5
1.6
—
—
—
0
0
295
2401
1.25
3.23
4.6
3.8
1.2
1.2
mmol/l
3.55
261
2088
139
1023
1.37
3.18
1.5
1.2
0.6
1.2
u/ml
—
10
89
174
1326
1.33
3.18
2.8
2.5
0.7
0.7
%
0.31
165
1267
2390
22935
1.14
3.15
23.6
19.4
331.7
332.2
g/l
2.48
2369
22759
29
146
1.99
3.04
1.1
1.3
—
—
—
0
0
44
256
1.73
2.97
2.1
2.2
1.1
1.1
e9/l
0.01
30
160
32
169
1.90
2.94
1.8
2.2
514.6
542.7
e6/l
0.11
27
143
20
88
2.28
2.93
2.1
2.2
28.1
29.6
%
0.21
20
81
248
2003
1.26
2.93
5.4
4.9
—
—
—
0
0
193
1513
1.29
2.90
3.2
2.9
0.2
0.3
e6/l
0.95
185
1475
31
165
1.89
2.80
1.4
1.3
—
—
—
0
0
56
354
1.59
2.79
2.4
2.4
—
—
—
0
0
304
2531
1.22
2.73
2.5
2.9
211.4
202.0
ng/l
0.16
263
2307
44
263
1.68
2.73
1.1
1.2
—
—
—
0
0
62
404
1.54
2.72
2.4
2.6
—
—
—
0
0
48
294
1.64
2.71
3.2
3.4
—
—
—
0
0
802
7239
1.14
2.70
4.0
3.4
—
—
—
0
0
89
626
1.43
2.69
1.6
1.7
—
—
—
0
0
829
7501
1.14
2.69
1.6
1.6
1.4
1.4
mmol/l
0.59
698
6271
27
140
1.94
2.65
1.1
1.1
9.6
13.1
iu/ml
—
7
43
529
4641
1.17
2.64
1.3
1.3
53.6
34.7
iu/ml
0.89
185
1462
35
198
1.78
2.63
2.3
2.2
14.2
14.1
%
0.02
19
80
307
2569
1.21
2.63
2.6
2.4
5.8
7.3
ug/l
1.13
274
2255
363
3087
1.20
2.62
3.8
4.1
29.6
26.4
ug/l
0.06
315
2510
53
336
1.59
2.62
1.4
1.5
—
—
—
0
0
122
912
1.35
2.59
5.6
4.2
3.9
3.9
mmol/l
0.22
105
852
2775
27026
1.15
2.53
4.9
4.7
6.1
6.0
mmol/l
2.73
2512
24548
14
56
2.51
2.53
2.1
2.1
111.1
156.2
e6/l
—
9
24
19
88
2.17
2.50
2.2
2.2
7.8
9.5
%
0.36
19
79
91
655
1.40
2.45
3.5
3.7
—
—
—
0
0
149
1158
1.30
2.44
2.9
2.6
—
—
—
0
0
89
640
1.40
2.42
3.7
3.1
1.8
1.6
mmol/l
0.73
89
619
44
273
1.62
2.40
2.0
1.3
16.4
31.1
iu/ml
—
5
11
303
2557
1.20
2.40
2.5
2.2
384.1
369.4
nmol/l
0.55
279
2339
13
52
2.51
2.35
1.2
1.1
—
—
—
0
0
96
703
1.38
2.35
1.2
1.2
—
—
—
0
0
44
275
1.61
2.34
2.2
2.4
—
—
—
0
0
69
477
1.46
2.33
1.2
1.2
—
—
—
0
0
2856
27911
1.15
2.31
5.3
5.1
2.7
2.7
mmol/l
2.23
2615
25625
99
732
1.36
2.29
1.8
1.9
10.5
11.8
mg/l
1.03
93
668
14
59
2.38
2.29
1.0
1.6
—
—
—
0
0
30
170
1.77
2.28
3.2
3.7
—
—
—
0
0
242
2010
1.22
2.27
1.4
1.4
—
—
—
0
0
90
657
1.38
2.26
1.6
1.9
4.0
4.7
iu/l
0.26
28
227
34
201
1.70
2.24
1.2
1.4
13.8
12.0
mmol/l
0.48
14
63
10
36
2.78
2.20
1.3
1.4
44.4
42.4
umol/l
—
10
36
11
42
2.62
2.18
1.2
1.4
61.9
121.5
ng/l
2.22
11
42
17
81
2.10
2.12
1.1
1.8
—
—
—
0
0
5
10
5.01
2.07
1.2
1.0
—
—
—
0
0
499
4441
1.15
2.06
1.3
1.3
12.7
12.1
u/ml
0.07
190
1713
82
600
1.38
2.06
3.9
3.2
7.8
7.5
mmol/l
0.25
82
582
57
391
1.47
2.04
2.3
2.5
—
—
—
0
0
91
679
1.35
2.03
4.1
4.6
8.4
8.5
kpa
0.12
85
670
90
675
1.34
1.95
4.1
4.5
2.3
2.7
mmol/l
0.57
67
474
90
676
1.34
1.93
4.1
4.5
5.1
5.0
kpa
0.07
84
668
25
142
1.77
1.92
1.9
2.3
—
—
—
0
0
16
78
2.06
1.90
4.6
5.1
—
—
—
0
0
16
78
2.06
1.90
2.7
2.1
—
—
—
0
0
649
5905
1.12
1.90
3.0
3.1
0.7
0.8
ug/l
1.16
446
3998
196
1627
1.22
1.89
1.5
1.3
311.5
209.3
u/ml
0.90
179
1498
159
1293
1.24
1.87
2.0
1.9
—
—
—
0
0
90
681
1.33
1.85
1.2
1.2
—
—
—
0
0
103
795
1.30
1.85
4.1
4.3
7.4
7.4
ph
0.18
84
667
31
190
1.64
1.84
2.1
1.4
—
—
—
0
0
75
554
1.36
1.81
1.3
1.4
—
—
—
0
0
31
191
1.63
1.80
1.2
1.1
—
—
—
0
0
16
80
2.00
1.79
1.0
1.1
—
—
—
0
0
121
959
1.27
1.78
1.2
1.3
36.2
31.3
iu/l
0.71
101
828
21
116
1.82
1.78
3.5
2.5
—
—
—
0
0
148
1202
1.24
1.77
1.6
1.6
—
20.5
—
0
32
798
7377
1.11
1.75
4.6
4.1
0.0
0.0
estimate
1.28
276
2458
45
306
1.48
1.73
1.2
1.3
284.1
278.0
mosm/kgh2o
1.65
39
231
41
274
1.50
1.71
1.5
1.5
—
—
—
0
0
71
526
1.36
1.70
3.0
2.7
—
—
—
0
0
69
509
1.36
1.70
3.3
3.1
—
—
—
0
0
91
700
1.31
1.70
1.6
1.7
8721.2
13262.7
e6/l
0.92
61
499
16
82
1.96
1.69
1.0
1.0
—
—
—
0
0
71
527
1.35
1.68
1.3
1.4
—
—
—
0
0
31
195
1.60
1.68
1.6
1.2
1.8
1.2
u/ml
0.18
15
92
22
126
1.75
1.67
1.3
1.1
—
—
—
0
0
64
468
1.37
1.67
1.3
1.2
376.3
280.9
u/ml
1.08
35
288
199
1681
1.20
1.64
1.2
1.2
135.3
151.1
iu/ml
0.21
54
616
95
740
1.29
1.63
2.9
3.1
24.4
24.9
mmol/l
0.59
89
641
26
158
1.65
1.62
2.4
2.1
154.8
165.0
ug/min
—
5
38
145
1190
1.23
1.60
6.3
4.7
—
—
—
0
0
46
321
1.44
1.57
1.6
1.5
—
—
—
0
0
193
1633
1.19
1.57
12.8
10.3
—
—
—
0
0
69
518
1.34
1.55
1.3
1.3
53.3
62.1
mmol/l
1.19
49
419
351
3117
1.14
1.54
2.2
2.2
124.2
142.8
ug/g
0.52
273
2465
46
323
1.43
1.53
1.5
1.2
44.5
55.5
u/ml
—
6
17
0
42
0.00
1.52
0.0
1.2
—
102.0
—
0
28
132
1080
1.23
1.52
3.7
3.4
1232.7
3973.2
u/ml
0.49
116
917
106
846
1.26
1.52
1.4
1.4
271.7
277.3
ug/g
0.10
68
495
2768
27155
1.11
1.51
4.7
4.5
1.4
1.5
mmol/l
7.65
2520
24926
55
400
1.38
1.51
1.7
1.5
30.9
32.2
g/l
0.28
48
360
79
608
1.31
1.50
2.9
3.1
0.8
0.8
nmol/l
0.13
61
469
80
618
1.30
1.48
1.4
1.3
—
—
—
0
0
40
276
1.45
1.47
1.4
1.4
28.6
30.0
%
0.09
25
171
10
45
2.23
1.46
1.0
1.0
—
—
—
0
0
2786
27354
1.11
1.45
4.7
4.5
4.5
4.6
mmol/l
4.34
2568
25261
46
329
1.40
1.40
1.7
1.4
19064.3
85105.1
e6/l
1.71
24
197
92
730
1.27
1.40
5.0
4.4
—
—
—
0
0
75
583
1.29
1.35
1.7
1.8
0.9
0.8
nmol/l
0.43
64
484
901
8475
1.09
1.34
4.5
4.0
—
—
—
0
0
213
1846
1.16
1.34
3.8
3.0
—
—
—
0
0
66
506
1.31
1.32
1.3
1.6
—
—
—
0
0
40
283
1.42
1.31
1.4
1.4
—
—
—
0
0
9
43
2.10
1.30
1.9
1.1
—
—
—
0
0
172
1470
1.18
1.29
4.3
3.4
—
—
—
0
0
217
1890
1.16
1.29
8.7
7.1
24.9
24.6
mmol/l
0.51
203
1758
92
739
1.25
1.29
1.3
1.4
—
14.1
—
0
18
33
226
1.46
1.28
2.2
2.1
1.5
1.9
u/field
0.39
15
90
588
5439
1.10
1.28
1.9
1.8
1094.1
1176.4
nmol/l
1.28
431
4102
62
474
1.31
1.27
1.4
1.4
93.5
121.4
u/ml
1.63
17
88
40
286
1.40
1.25
1.7
1.4
—
—
—
0
0
160
1364
1.18
1.25
1.5
1.8
1.7
1.5
g/l
0.93
133
1181
17
100
1.70
1.23
1.7
1.5
2.1
2.0
umol/l
0.08
17
93
2673
26249
1.09
1.23
4.2
4.0
1.3
1.3
mmol/l
2.39
2422
23919
43
315
1.37
1.18
13.1
6.3
7.1
7.4
mmol/l
0.27
37
261
8
38
2.11
1.18
1.7
1.3
79.5
74.6
%
—
8
32
27
181
1.50
1.18
1.6
2.1
707.2
700.6
e6/l
—
10
74
77
616
1.26
1.14
1.2
1.3
10.0
10.3
u/l
0.06
59
505
21
134
1.57
1.14
1.0
1.0
—
—
—
0
0
22
142
1.55
1.14
2.2
3.7
—
—
—
0
0
86
698
1.24
1.13
1.5
1.2
6.7
3.2
u/ml
0.63
15
77
52
396
1.32
1.13
1.2
1.1
0.3
1.7
u/ml
2.29
20
164
62
485
1.28
1.11
2.2
3.5
1.3
1.4
%
0.06
46
373
124
1047
1.19
1.11
1.7
2.0
23.1
21.5
s
0.69
114
923
7
31
2.26
1.10
2.0
1.5
—
—
—
0
0
24
160
1.50
1.09
1.7
1.7
—
—
—
0
0
8
41
1.95
1.08
2.5
1.5
—
—
—
0
0
216
1910
1.14
1.07
2.6
3.1
4.3
4.1
e9/l
0.53
154
1474
142
1217
1.17
1.07
2.2
2.0
2.8
2.4
ug/l
0.12
126
1075
59
463
1.28
1.04
1.2
1.3
—
—
—
0
0
20
130
1.54
1.02
2.2
3.8
—
—
—
0
0
76
617
1.24
1.02
2.4
2.8
—
—
—
0
0
25
172
1.46
0.99
1.1
1.1
—
—
—
0
0
1066
10198
1.07
0.99
5.0
5.0
2.3
3.4
ug/l
1.87
943
9133
5
23
2.18
0.98
1.0
1.1
—
—
—
0
0
0
29
0.00
0.97
0.0
11.8
—
—
—
0
0
41
310
1.33
0.96
1.7
1.5
—
—
—
0
0
45
345
1.31
0.96
1.1
1.1
2.2
4.6
u/ml
1.37
21
170
20
295
0.68
0.96
1.2
1.2
—
—
—
0
0
316
2883
1.11
0.95
1.7
1.6
—
—
—
0
0
35
259
1.36
0.95
1.1
1.1
—
—
—
0
0
41
312
1.32
0.93
2.4
4.1
—
—
—
0
0
78
644
1.22
0.92
2.6
3.3
2163.2
735.0
u/ml
0.48
72
592
85
709
1.20
0.91
1.5
1.2
17.0
7.9
u/ml
0.34
16
126
74
609
1.22
0.90
1.3
1.4
15.2
26.6
e6/l
0.47
55
472
74
609
1.22
0.90
1.3
1.4
741.6
1433.2
e6/l
0.52
58
495
27
193
1.40
0.90
1.1
1.2
—
—
—
0
0
47
367
1.28
0.89
1.7
1.4
2334.5
1724.4
e6/l
0.40
31
267
170
1503
1.14
0.89
2.4
2.4
—
—
—
0
0
43
335
1.29
0.84
1.1
1.1
0.1
1.6
u/ml
2.12
20
143
6
31
1.94
0.84
1.2
1.3
—
—
—
0
0
18
121
1.49
0.82
1.1
1.2
—
—
—
0
0
21
146
1.44
0.82
1.0
1.1
—
—
—
0
0
12
73
1.65
0.81
1.1
1.0
—
—
—
0
0
12
73
1.65
0.81
1.1
1.0
—
—
—
0
0
12
73
1.65
0.81
1.1
1.0
—
—
—
0
0
14
89
1.58
0.81
1.3
1.2
—
—
—
0
0
84
711
1.19
0.79
2.6
2.3
56.8
105.3
ug/min
1.56
59
437
26
190
1.37
0.79
1.1
1.1
—
—
—
0
0
12
74
1.62
0.78
1.4
1.3
49.5
144.4
ug/l
—
7
35
14
90
1.56
0.78
1.5
1.4
4.0
3.3
mmol/l
0.32
14
80
73
612
1.20
0.77
4.5
3.6
21.2
28.0
mg/l
1.15
53
383
624
5919
1.07
0.76
4.7
4.2
1.0
1.0
kg/l
0.06
84
872
57
467
1.22
0.76
1.6
1.3
—
—
—
0
0
122
1069
1.15
0.76
1.1
1.1
—
—
—
0
0
57
468
1.22
0.75
1.5
1.4
—
—
—
0
0
49
397
1.24
0.73
6.0
6.7
12.2
11.9
mg/l
0.16
44
373
7
39
1.80
0.72
1.3
1.1
—
—
—
0
0
190
1719
1.11
0.72
1.4
1.3
84.4
47.7
au/ml
—
7
75
198
1797
1.11
0.71
3.8
3.6
7.4
7.4
ph
0.00
39
217
5
26
1.92
0.70
3.2
2.8
—
—
—
0
0
5
26
1.92
0.70
6.4
5.7
—
—
—
0
0
601
5711
1.06
0.70
1.3
1.2
1.5
1.6
u/ml
0.05
157
1506
151
1684
0.89
0.69
1.6
1.6
—
—
—
0
0
208
1895
1.10
0.69
2.5
2.4
34.8
24.3
au/ml
—
8
93
11
69
1.60
0.68
1.2
1.1
—
—
—
0
0
82
949
0.86
0.66
7.7
6.5
1.4
1.3
mmol/l
0.16
74
830
22
163
1.35
0.64
1.1
1.0
—
—
—
0
0
199
1820
1.10
0.63
3.8
3.6
5.2
5.1
kpa
0.22
190
1676
21
280
0.75
0.62
1.5
1.4
—
—
—
0
0
6
101
0.59
0.62
9.5
6.8
25.9
25.0
mmol/l
—
6
90
11
71
1.55
0.62
2.0
1.9
5.3
9.1
mg/l
—
5
58
78
674
1.16
0.62
2.4
2.1
—
—
—
0
0
22
290
0.76
0.61
1.5
1.5
—
—
—
0
0
16
113
1.42
0.61
2.3
2.1
—
—
—
0
0
24
312
0.77
0.60
1.3
1.5
0.1
0.3
nmol/l
5.10
18
231
58
490
1.19
0.60
1.2
1.2
22.6
39.9
u/l
1.19
52
424
0
21
0.00
0.60
0.0
4.1
—
—
—
0
0
43
353
1.22
0.60
1.3
1.2
—
—
—
0
0
12
80
1.50
0.59
2.6
1.5
—
—
—
0
0
47
561
0.84
0.57
1.5
1.7
—
—
—
0
0
643
6170
1.05
0.55
1.8
1.7
433.0
31548511.7
pmol/l
5.03
531
5116
82
932
0.88
0.55
13.5
10.2
—
—
—
0
0
255
2377
1.08
0.55
4.9
4.1
—
—
—
0
0
23
177
1.30
0.54
1.1
1.2
45.2
34.1
mmol/l
0.73
16
154
38
312
1.22
0.54
1.0
1.1
0.1
2.2
u/ml
—
6
73
14
99
1.42
0.54
2.1
1.9
55.3
52.1
ug/l
0.09
14
94
776
7490
1.05
0.53
1.4
1.4
—
—
—
0
0
22
281
0.78
0.51
1.6
1.4
—
—
—
0
0
30
242
1.24
0.51
1.2
1.2
377.7
386.4
nmol/l
0.08
23
209
30
242
1.24
0.51
1.0
1.1
0.9
4.1
u/ml
2.33
11
95
109
981
1.11
0.50
1.7
1.6
—
—
—
0
0
43
361
1.19
0.50
1.1
1.1
—
—
—
0
0
43
361
1.19
0.50
1.1
1.1
—
—
—
0
0
41
344
1.19
0.49
1.0
1.1
2.3
2.3
u/ml
0.04
15
149
67
587
1.14
0.48
4.2
3.6
60.1
57.8
%
0.90
67
587
71
625
1.14
0.47
2.5
2.8
30.8
36.3
umol/l
1.47
60
528
23
285
0.81
0.43
1.3
1.2
—
—
—
0
0
44
377
1.17
0.43
1.2
1.3
—
—
—
0
0
52
452
1.15
0.43
1.1
1.1
127.7
1323.0
iu/ml
—
10
98
90
812
1.11
0.42
1.2
1.2
—
—
—
0
0
196
1833
1.07
0.42
1.2
1.2
—
—
—
0
0
133
1440
0.92
0.40
1.4
1.5
—
—
—
0
0
160
1488
1.08
0.40
1.3
1.2
—
—
—
0
0
214
2012
1.07
0.40
1.2
1.2
—
—
—
0
0
14
107
1.31
0.37
2.6
2.3
—
—
—
0
0
199
2112
0.94
0.37
1.4
1.4
—
—
—
0
0
46
402
1.15
0.37
4.8
5.3
352.1
356.2
umol/l
0.07
36
350
34
397
0.85
0.37
1.1
1.2
—
—
—
0
0
15
116
1.29
0.37
1.1
1.1
0.3
1.1
u/ml
—
6
36
6
42
1.43
0.35
1.8
2.0
16.4
18.8
umol/l
—
6
42
52
585
0.89
0.34
2.0
2.0
—
—
—
0
0
40
348
1.15
0.34
1.2
1.6
58.1
60.9
%
0.17
25
214
6
44
1.36
0.34
3.0
1.6
16.9
35.1
pmol/l
—
6
38
6
45
1.33
0.33
2.0
1.5
—
—
—
0
0
12
91
1.32
0.33
2.0
2.4
—
—
—
0
0
28
237
1.18
0.33
1.5
1.6
—
—
—
0
0
28
238
1.18
0.32
2.6
2.2
522.7
610.6
ml
0.54
19
156
26
220
1.18
0.31
1.0
1.0
0.1
0.4
u/ml
—
7
57
27
230
1.18
0.31
2.0
1.9
11.8
11.2
%
0.23
27
230
27
315
0.86
0.30
1.8
1.8
—
1069.1
—
0
11
91
841
1.08
0.30
1.1
1.1
—
—
—
0
0
54
488
1.11
0.28
1.4
1.5
—
—
—
0
0
14
112
1.25
0.28
1.1
1.0
0.5
0.4
u/ml
—
5
28
12
94
1.28
0.28
1.2
1.1
—
—
—
0
0
32
280
1.14
0.27
1.4
1.3
213324.4
88709.3
e6/l
0.26
24
194
48
432
1.11
0.27
1.1
1.1
—
—
—
0
0
40
356
1.13
0.27
1.1
1.3
—
—
nmol/l
—
0
0
45
404
1.12
0.27
2.2
2.9
—
—
—
0
0
10
77
1.30
0.26
1.3
1.1
—
—
—
0
0
18
213
0.84
0.25
1.1
1.0
834.7
711.4
ng/l
0.43
11
137
45
407
1.11
0.24
1.2
1.3
0.7
0.6
nmol/l
0.25
45
388
19
161
1.18
0.24
1.8
2.4
88.7
25.9
umol/l
—
5
15
35
312
1.12
0.24
2.7
2.0
—
—
—
0
0
232
2412
0.96
0.24
3.7
3.5
—
—
—
0
0
60
651
0.92
0.23
1.3
1.3
148.3
217.4
miu/ml
1.14
22
285
26
296
0.88
0.23
1.7
2.0
—
—
—
0
0
24
209
1.15
0.22
1.3
1.2
—
—
—
0
0
34
304
1.12
0.22
1.1
1.1
—
—
—
0
0
137
1303
1.05
0.22
4.0
3.8
—
—
—
0
0
16
189
0.85
0.22
1.4
1.5
70.0
223.1
pmol/l
—
6
58
30
267
1.12
0.21
1.5
1.6
—
—
—
0
0
0
13
0.00
0.21
0.0
1.6
—
12.6
—
0
13
44
402
1.10
0.20
1.4
1.3
—
—
—
0
0
83
780
1.07
0.20
1.1
1.1
—
—
—
0
0
6
48
1.25
0.20
2.2
1.6
—
—
—
0
0
59
635
0.93
0.20
1.9
1.9
—
—
—
0
0
6
51
1.18
0.19
5.8
5.6
—
—
—
0
0
80
754
1.06
0.18
1.3
1.2
115.0
100.2
titre
—
6
58
13
109
1.19
0.18
3.8
2.8
172.9
171.0
umol/l
—
8
62
60
642
0.93
0.18
1.2
1.2
—
—
—
0
0
17
147
1.16
0.18
1.2
1.2
—
—
—
0
0
23
204
1.13
0.18
2.4
1.5
1.0
0.9
g/l
0.64
23
204
59
631
0.93
0.18
1.9
1.9
—
—
—
0
0
63
590
1.07
0.18
1.6
2.1
6431.5
3918.0
u/l
0.26
25
243
20
176
1.14
0.17
1.1
1.5
4.0
4.7
ug/l
0.16
20
144
36
330
1.09
0.16
2.9
2.6
—
—
—
0
0
303
2955
1.03
0.16
4.2
4.4
—
—
—
0
0
10
120
0.83
0.16
1.6
1.4
—
—
—
0
0
12
101
1.19
0.16
2.6
1.6
—
—
—
0
0
8
70
1.14
0.16
1.5
1.6
—
—
—
0
0
38
350
1.09
0.16
4.2
3.3
5.9
20.6
nmol/l
0.45
38
343
8
71
1.13
0.16
1.1
1.0
—
—
—
0
0
59
627
0.94
0.15
1.9
2.0
—
—
—
0
0
9
78
1.15
0.15
1.2
1.4
23.9
22.9
%
—
9
61
37
400
0.92
0.15
1.3
1.2
6.1
5.0
u/ml
0.11
14
168
213
2071
1.03
0.15
1.9
2.2
11.2
12.6
nmol/l
1.88
188
1818
19
213
0.89
0.15
1.1
1.0
371.0
323.5
ng/l
0.27
11
139
19
169
1.12
0.14
1.1
1.0
—
—
—
0
0
7
88
0.80
0.14
1.6
1.7
—
—
—
0
0
7
89
0.79
0.14
1.3
1.3
—
—
—
0
0
44
411
1.07
0.14
1.2
1.3
0.1
0.4
nmol/l
—
5
24
949
9389
1.01
0.14
3.3
2.9
—
—
—
0
0
8
100
0.80
0.13
1.1
1.4
—
—
—
0
0
12
104
1.15
0.12
3.2
1.9
23.5
99.8
ug/l
0.49
12
91
30
280
1.07
0.10
1.1
1.2
—
—
—
0
0
11
125
0.88
0.10
1.4
1.7
3.3
8.0
nmol/l
0.64
11
106
33
310
1.07
0.09
1.2
1.4
20.5
29.9
u/l
1.14
26
252
20
184
1.09
0.09
1.6
1.4
2214.4
2037.9
ml
—
7
36
11
124
0.89
0.09
1.0
1.2
—
—
—
0
0
15
136
1.10
0.08
13.7
11.3
0.7
0.6
mmol/l
0.25
15
123
5
63
0.79
0.08
1.0
1.9
—
—
—
0
0
16
146
1.10
0.08
2.3
2.8
—
—
—
0
0
5
64
0.78
0.08
1.4
1.2
14.8
16.5
umol/l
—
5
57
29
273
1.06
0.08
1.2
1.2
—
—
—
0
0
60
622
0.96
0.08
1.9
1.8
—
—
—
0
0
51
491
1.04
0.07
2.0
1.9
—
—
—
0
0
7
84
0.83
0.07
1.3
1.3
—
—
—
0
0
9
85
1.06
0.07
2.0
2.3
—
—
—
0
0
9
86
1.05
0.07
1.7
1.7
—
—
—
0
0
9
87
1.03
0.07
1.1
1.1
—
—
—
0
0
9
88
1.02
0.07
2.3
2.2
—
—
—
0
0
120
1223
0.98
0.06
1.9
1.7
—
—
—
0
0
31
296
1.05
0.05
2.3
3.5
56.2
56.6
%
0.03
20
185
19
178
1.07
0.05
1.0
1.1
0.3
7.7
nmol/l
—
5
39
28
267
1.05
0.05
1.0
1.1
4.4
3.2
u/ml
—
9
101
26
273
0.95
0.05
2.5
2.3
—
—
—
0
0
11
100
1.10
0.05
1.3
1.1
—
—
—
0
0
11
120
0.92
0.05
1.2
1.2
182.0
206.7
iu/ml
0.11
11
120
29
278
1.04
0.04
2.4
2.5
—
—
—
0
0
11
101
1.09
0.04
1.2
1.0
—
—
—
0
0
103
1014
1.02
0.04
2.8
3.1
0.5
0.3
g/l
0.52
48
406
27
281
0.96
0.04
1.7
1.8
—
—
—
0
0
35
361
0.97
0.03
1.3
1.2
—
—
—
0
0
21
219
0.96
0.03
1.0
1.0
—
—
—
0
0
14
132
1.06
0.02
9.6
13.1
1029.5
815.9
nmol/l
0.91
14
125
46
450
1.02
0.02
1.1
1.1
—
—
—
0
0
113
1120
1.01
0.01
4.2
3.9
25.2
24.8
mmol/l
0.70
106
1029
13
137
0.95
0.01
13.5
13.1
—
—
—
0
0
201
1999
1.01
0.01
1.3
1.3
—
—
—
0
0
14
147
0.95
0.01
1.4
1.3
185.9
335.3
u/l
0.84
14
138
33
337
0.98
0.01
1.6
1.4
—
—
—
0
0
11
104
1.06
0.01
1.2
1.1
2104.2
1625.0
miu/ml
0.54
11
104
20
206
0.97
0.00
1.2
1.4
1.3
1.3
promille
0.07
15
156
10
102
0.98
0.00
1.1
1.1
—
—
—
0
0
15
152
0.99
0.00
1.1
1.2
132.9
137.4
nmol/l
0.17
15
152
31
308
1.01
0.00
1.4
1.2
—
—
—
0
0
16
155
1.03
0.00
1.1
1.1
1.1
1.0
ratio
—
6
58
17
171
0.99
0.00
2.8
2.8
36.4
39.2
%
—
7
59
15
146
1.03
0.00
2.1
1.7
—
—
—
0
0
34
337
1.01
0.00
1.6
1.4
—
—
—
0
0
34
337
1.01
0.00
1.6
1.4
—
—
—
0
0
34
337
1.01
0.00
1.6
1.4
—
—
—
0
0
18
177
1.02
0.00
2.2
1.6
—
—
—
0
0
25
253
0.99
0.00
2.6
2.0
—
1.5
—
0
11
0
9
0.00
0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
0.00
0.0
1.6
—
2984.0
—
0
5
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
20
200
1.00
0.00
2.0
2.4
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
21.9
—
0
5
8
84
0.95
0.00
1.0
1.2
—
—
—
0
0
0
8
0.00
0.00
0.0
2.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.6
—
0.6
—
0
5
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
6
63
0.95
0.00
1.0
1.2
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.7
—
—
—
0
0
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
2.2
—
4.7
—
0
6
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
7
77
0.91
0.00
1.3
1.6
—
—
—
0
0
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
6
60
1.00
0.00
2.7
2.1
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
0.00
0.0
1.9
—
—
—
0
0
0
6
0.00
0.00
0.0
5.0
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint CD2_BENIGN_SALIVARY_KNOWN and mortality.

Females

Parameter HR [95% CI] p-value
CD2_BENIGN_SALIVARY_KNOWN 1.245 [1.13, 1.37] < 0.001
Birth year 0.995 [0.99, 1.0] 0.204

During the follow-up period (1.1.1998 — 31.12.2019), 1747 out of 9004 females with CD2_BENIGN_SALIVARY_KNOWN died.

Males

Parameter HR [95% CI] p-value
CD2_BENIGN_SALIVARY_KNOWN 1.447 [1.31, 1.6] < 0.001
Birth year 0.988 [0.98, 1.0] 0.008

During the follow-up period (1.1.1998 — 31.12.2019), 2033 out of 8254 males with CD2_BENIGN_SALIVARY_KNOWN died.

Mortality risk

Mortality risk for people of age

years, who have CD2_BENIGN_SALIVARY_KNOWN.

N-year risk Females Males
1 0.106% 0.249%
5 0.728% 1.388%
10 1.937% 4.022%
15 3.849% 7.767%
20 6.407% 12.739%

Relationships between endpoints

Index endpoint: CD2_BENIGN_SALIVARY_KNOWN – Benign neoplasm: salivary glands, exclude unknown (D119)

GWS hits: 1

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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