pulmonary edema: Excessive accumulation of extravascular fluid in the lung, an indication of a serious underlying disease or disorder. Pulmonary edema prevents efficient PULMONARY GAS EXCHANGE in the PULMONARY ALVEOLI, and can be life-threatening.
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
519972 |
1. Apply sex-specific ruleNone |
519972 |
2. Check conditionsNone |
519972 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
712 |
4. Check minimum number of eventsNone |
712 |
5. Include endpointsNone |
712 |
6. Filter based on genotype QC (FinnGen only) |
681 |
Control definitions (FinnGen only)
- Control exclude
- J10_INTERSTITIUM
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF6
- Parent code in ICD-10
- J80-J84
- Name in latin
- Oedema pulmonum
Similar endpoints
↥List of similar endpoints to
Pulmonary oedema
based on the number of shared cases.
Similar with more cases:
- Other respiratory diseases principally affecting the interstitium
- Other pulmonary diagnosis
- Excluding asthma or asthma-COPD overlap
- COPD differential diagnosis
- ILD differential diagnosis
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 9006 | 4604 | 4219 |
| Only index persons | 5204 | 2779 | 2425 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.13 | 0.13 | 0.12 |
| Only index persons | 0.10 | 0.10 | 0.09 |
| Median age at first event (years) | |||
| Whole population | 77.49 | 80.34 | 74.43 |
| Only index persons | 76.85 | 79.98 | 73.26 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 681 | 259 | 422 |
| Unadjusted period prevalence (%) | 0.15 | 0.09 | 0.19 |
| Median age at first event (years) | 73.88 | 74.39 | 73.56 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 712
- Matched controls
- 7116
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
J81
ICD-10 Finland
Pulmonary oedema
+∞
307.7
712
*
I50.0
ICD-10 Finland
Congestive heart failure
7.0
134.6
277
590
I50.9
ICD-10 Finland
Heart failure, unspecified
6.0
127.8
393
1204
C03CA01
ATC
furosemide; systemic
7.3
117.9
569
2516
I50.1
ICD-10 Finland
Left ventricular failure
7.4
105.1
181
315
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
5.2
98.4
288
816
WX722
NOMESCO Finland
PEEP
7.8
77.4
117
174
TK800
NOMESCO Finland
Hemodialysis
14.2
76.1
72
56
Z49.1
ICD-10 Finland
Extracorporeal dialysis
17.6
68.3
57
35
138
Kela drug reimbursment
Severe anaemia associated with chronic renal failure
10.4
66.2
77
82
WX872
NOMESCO Finland
Intensive care
7.0
64.0
106
173
123
Kela drug reimbursment
Chronic disorders of vitamin D metabolism
9.9
59.0
71
79
PBL10
NOMESCO Finland
Construction of arteriovenous fistula from radial artery
17.7
54.3
45
27
N18.9
ICD-10 Finland
Chronic kidney disease, unspecified
4.5
49.5
141
372
C03DA01
ATC
spironolactone; oral
3.7
48.1
195
661
N18.8
ICD-10 Finland
Other chronic renal failure
7.8
46.5
67
93
I25.1
ICD-10 Finland
Atherosclerotic heart disease
3.0
45.2
346
1704
J96.0
ICD-10 Finland
Acute respiratory failure
12.2
45.1
46
40
201
Kela drug reimbursment
Chronic cardiac insufficiency
4.1
45.0
143
408
FN1AC
NOMESCO Finland
Angiography of heart and/or coronary arteries
3.0
42.4
287
1311
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
5.1
41.6
95
208
J18.9
ICD-10 Finland
Pneumonia, unspecified
2.8
39.1
343
1781
WX730
NOMESCO Finland
Conventional respirator
9.9
37.4
44
47
C01DA14
ATC
isosorbide mononitrate; oral
2.8
37.3
286
1378
E11.7
ICD-10 Finland
Type 2 diabetes mellitus, with multiple complications
4.1
36.6
111
304
A11CC03
ATC
alfacalcidol; systemic
7.1
36.1
56
84
N18.0
ICD-10 Finland
End-stage renal disease
11.1
36.0
39
37
V03AE01
ATC
polystyrene sulfonate; oral
9.9
35.6
42
45
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
2.9
35.0
224
976
I21.49
ICD-10 Finland
Acute subendocardial infarction unspecified coronary artery status
3.8
34.9
121
364
103
Kela drug reimbursment
Diabetes, insulin-treated
2.7
34.8
305
1561
TPH07
NOMESCO Finland
Cathetrisation of artery
3.4
33.8
145
501
AN1
HP
Coronary angiography
3.1
33.1
170
653
I25.2
ICD-10 Finland
Old myocardial infarction
3.4
33.0
143
496
A12AA04
ATC
calcium carbonate; oral
8.9
32.9
42
50
WX882
NOMESCO Finland
High dependency care
6.1
32.1
58
102
ZXD05
NOMESCO Finland
Urgent procedure
2.6
31.0
287
1489
C07AB07
ATC
bisoprolol; oral
2.6
30.8
480
3163
TPH90
NOMESCO Finland
Removal of fixed intravenous catheter
10.8
29.1
32
31
E11.9
ICD-10 Finland
Type 2 diabetes mellitus, without complications
2.5
29.0
274
1427
B03XA02
ATC
darbepoetin alfa; parenteral
6.8
28.5
46
72
A10AC01
ATC
insulin (human); parenteral
3.4
28.1
116
389
A10AE04
ATC
insulin glargine; parenteral
3.3
27.9
122
423
TPH04
NOMESCO Finland
Cathetrisation of vein
2.6
27.6
213
1004
WX892
NOMESCO Finland
Monitored bed care
3.7
27.4
96
289
205
Kela drug reimbursment
Chronic hypertension
2.4
27.1
333
1936
206
Kela drug reimbursment
Chronic coronary artery disease and dyslipidaemia associated with chronic coronary artery disease
2.4
26.9
276
1481
A10AB05
ATC
insulin aspart; parenteral
3.6
26.5
96
295
N08.39*E11.2
ICD-10 Finland
Non-insulin-dependent diabetes mellitus - Diabetic nephropathy
7.6
25.6
37
51
GA4YT
NOMESCO Finland
Puncture of pleura with ultrasound guidance
4.7
25.5
62
142
R06.0
ICD-10 Finland
Dyspnoea
2.4
25.5
256
1355
TFB00
NOMESCO Finland
Cathetrisation of pulmonal artery
7.6
24.3
35
48
I70.2
ICD-10 Finland
Atherosclerosis of arteries of extremities
2.7
24.1
151
637
TPX10
NOMESCO Finland
Implantation of vascular injection port
5.6
24.0
47
89
A10AB01
ATC
insulin (human); parenteral
5.0
23.7
53
113
190
Kela drug reimbursment
Lanthanum carbonate, sevelamer and sucroferric oxyhydroxide
20.4
23.7
35
18
C01AA05
ATC
digoxin; systemic
2.6
23.6
164
729
I25.9
ICD-10 Finland
Chronic ischaemic heart disease, unspecified
2.5
23.2
175
808
C01BD01
ATC
amiodarone; systemic
5.3
23.1
48
96
E11.8
ICD-10 Finland
Type 2 diabetes mellitus, with unspecified complications
2.8
23.0
133
538
XF400
NOMESCO Finland
ECG with 12 standard connections
2.5
23.0
186
888
ZX120
NOMESCO Finland
Intravenous
3.1
22.7
104
369
E11.2
ICD-10 Finland
Type 2 diabetes mellitus, with renal complications
4.2
22.4
62
157
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
2.5
22.0
161
732
B01AA03
ATC
warfarin; systemic
2.2
21.7
266
1511
A12BA01
ATC
potassium chloride; oral
3.1
21.2
95
332
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
2.7
21.2
129
534
N17.9
ICD-10 Finland
Acute renal failure, unspecified
3.8
21.2
67
187
I21.41
ICD-10 Finland
Acute subendocardial infarction stenosed coronary artery
3.5
20.7
76
235
I11.0
ICD-10 Finland
Hypertensive heart disease with (congestive) heart failure
3.9
20.5
64
177
C01DA02
ATC
glyceryl trinitrate; oral, oral aerosol, sublingual, transdermal
2.1
20.3
296
1790
I48
ICD-10 Finland
Atrial fibrillation and flutter
2.1
20.0
286
1714
WX725
NOMESCO Finland
Noninvasive ventilation
4.0
19.9
60
162
FM1BE
NOMESCO Finland
Cardiac ultrasound examination through oesophagus
3.4
19.9
75
236
A10AE05
ATC
insulin detemir; parenteral
3.7
19.6
64
183
I21.99
ICD-10 Finland
Myocardial infarction (acute) UNS unspecified coronary artery status
3.8
19.4
63
179
FXA00
NOMESCO Finland
Total cardiopulmonary bypass in normothermia or moderate hypothermia at concurrent surgical procedure
3.8
19.3
61
170
A10BB12
ATC
glimepiride; oral
2.8
19.2
111
446
TKC20
NOMESCO Finland
Catheterisation of bladder
2.9
19.2
100
380
C09AA05
ATC
ramipril; oral
2.1
19.2
264
1553
A10AA02, ,
ATC
3.9
19.1
59
162
E10.7
ICD-10 Finland
Type 1 diabetes mellitus, With multiple complications
6.1
18.8
33
56
A10AA01, ,
ATC
5.8
18.8
35
63
ZXE30
NOMESCO Finland
More than five and less than seven hours
4.0
18.8
55
145
A10BA02
ATC
metformin; oral
2.1
18.4
267
1597
WX704
NOMESCO Finland
Intubation
3.3
18.4
73
237
I46.0
ICD-10 Finland
Cardiac arrest with successful resuscitation
6.3
18.2
31
51
215
Kela drug reimbursment
Diabetes, non-insulin-treated
2.2
18.2
201
1083
B01AC04
ATC
clopidogrel; oral
2.2
18.2
186
972
N08.39*E10.2
ICD-10 Finland
Insulin-dependent diabetes mellitus - Diabetic nephropathy
27.5
17.9
24
9
L04AA06
ATC
mycophenolic acid; systemic
14.2
17.9
30
22
320
Kela drug reimbursment
Lanthanum carbonate, sevelamer and sucroferric oxyhydroxide
20.7
17.8
26
13
Z94.0
ICD-10 Finland
Kidney transplant status
23.5
17.8
25
11
J84.1
ICD-10 Finland
Other interstitial pulmonary diseases with fibrosis
184.3
17.6
18
*
XCK10
NOMESCO Finland
Photography of fundus of eye
2.7
17.3
104
426
L97
ICD-10 Finland
Ulcer of lower limb, not elsewhere classified
3.9
17.1
52
141
127
Kela drug reimbursment
Transplant complication
14.5
16.9
28
20
C08CA01
ATC
amlodipine; oral
2.0
16.8
338
2252
C09AA02
ATC
enalapril; systemic
2.1
16.7
214
1215
FN1AT
NOMESCO Finland
Endovascular dilatation of coronary arteries (PTCA)
3.1
16.4
72
248
J15.9
ICD-10 Finland
Bacterial pneumonia, unspecified
2.4
16.3
125
574
I25.5
ICD-10 Finland
Ischaemic cardiomyopathy
4.4
16.2
41
97
C08CA02
ATC
felodipine; oral
2.5
16.1
118
531
I20.81
ICD-10 Finland
Other angina pectoris stenosed coronary artery
2.5
16.0
112
494
I42.0
ICD-10 Finland
Dilated cardiomyopathy
4.4
16.0
41
98
Z49.0
ICD-10 Finland
Preparatory care for dialysis
13.3
15.8
27
21
196
Kela drug reimbursment
Paricalcitol and cinacalcet
27.0
15.7
21
8
V03AE02
ATC
sevelamer; oral
27.0
15.7
21
8
A41.9
ICD-10 Finland
Sepsis, unspecified
3.5
15.6
55
165
TFC00
NOMESCO Finland
Catheterisation of right atrium or ventricle
6.4
15.6
26
42
I25.0
ICD-10 Finland
Atherosclerotic cardiovascular disease, so described
2.6
15.5
97
404
FM1DE
NOMESCO Finland
Doppler ultrasound examination of heart
2.6
15.5
102
436
WW500
NOMESCO Finland
Blood transfusion
3.5
15.5
56
171
FB1BD
NOMESCO Finland
Extensive CT examination of arteria pulmonalis
3.0
15.4
70
246
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
2.0
15.3
204
1170
L04AD02
ATC
tacrolimus; systemic
29.3
15.2
20
7
C02AC05
ATC
moxonidine; oral
3.3
15.2
61
199
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
2.0
15.1
201
1152
A41.0
ICD-10 Finland
Sepsis due to Staphylococcus aureus
4.8
15.1
34
73
A10BB01
ATC
glibenclamide; oral
2.7
14.7
82
322
M04AA01
ATC
allopurinol; systemic
2.1
14.7
159
842
J80
ICD-10 Finland
Adult respiratory distress syndrome
+∞
14.6
14
*
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.9
14.5
357
2500
E11.5
ICD-10 Finland
Type 2 diabetes mellitus, with peripheral circulatory complications
4.2
14.4
39
97
E11.00
ICD-10 Finland
Non-insulin dependent diabetes diabetic hypoglycaemic coma
3.2
14.2
57
186
QDB05
NOMESCO Finland
Revision of wound of skin of lower limb
4.5
14.2
35
81
N17.8
ICD-10 Finland
Other acute renal failure
6.8
14.1
22
33
FNA01
NOMESCO Finland
Anastomosis to coronary artery from internal mammary artery, one distal anastamosis
2.8
14.0
73
277
TPH30
NOMESCO Finland
Insertion of central venous catheter through periferal vein
6.4
13.8
23
37
I50
ICD-10 Finland
Heart failure
3.2
13.8
56
184
I42.9
ICD-10 Finland
Cardiomyopathy, unspecified
5.8
13.7
25
44
ZXD30
NOMESCO Finland
Difficulties in perfomrming procedure
3.6
13.7
46
134
ZXE20
NOMESCO Finland
More than three and less than five hours
2.2
13.5
124
614
TK810
NOMESCO Finland
Hemofiltration
21.6
13.4
19
9
A49.9
ICD-10 Finland
Bacterial infection, unspecified
2.2
13.2
122
604
I35.0
ICD-10 Finland
Aortic (valve) stenosis
2.5
13.1
90
392
KAS10
NOMESCO Finland
Allogenic transplantation of kidney from cadaver donor
23.0
12.9
18
8
XPX99
NOMESCO Finland
Other diagnostic examination of periferal vessel
2.6
12.9
77
313
I20.09
ICD-10 Finland
Unstable angina
2.6
12.8
81
339
E11.6
ICD-10 Finland
Type 2 diabetes mellitus, with other specified complications
4.4
12.8
32
75
I47.2
ICD-10 Finland
Ventricular tachycardia
4.5
12.7
31
71
1CX08, ,
NOMESCO Finland
24.8
12.5
17
7
A10AD05
ATC
insulin aspart; parenteral
3.9
12.4
37
99
137
Kela drug reimbursment
Uraemia requiring dialysis
12.7
12.2
21
17
B03XA03
ATC
methoxy polyethylene glycol-epoetin beta; parenteral
12.7
12.2
21
17
C07AB02
ATC
metoprolol; systemic
1.9
12.1
217
1360
QDB10
NOMESCO Finland
Major dressing of wound of skin of lower limb
2.9
12.0
59
217
E10.2
ICD-10 Finland
Type 1 diabetes mellitus, With renal complications
15.0
11.8
19
13
N19
ICD-10 Finland
Unspecified kidney failure
3.0
11.7
54
191
A46
ICD-10 Finland
Erysipelas
2.0
11.7
136
735
J84.9
ICD-10 Finland
Interstitial pulmonary disease, unspecified
66.0
11.6
13
*
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
2.2
11.5
107
530
D62
ICD-10 Finland
Acute posthaemorrhagic anaemia
5.5
11.4
22
41
FN1YT
NOMESCO Finland
Percutaneous insertion of coronary artery stent
2.6
11.4
71
295
C10AA01
ATC
simvastatin; oral
1.7
11.3
372
2766
H3603, E103,
ICD-10 Finland
35.6
11.3
14
*
V03AE03
ATC
lanthanum carbonate; oral
25.5
11.2
15
6
WZC10
NOMESCO Finland
Written specialist consultation based on a referral from a dentist or a physician
3.4
11.0
40
123
L04AX01
ATC
azathioprine; systemic
3.8
11.0
33
89
PG5RT
NOMESCO Finland
PTA of arterio-venous shunt for dialysis
44.0
10.9
13
*
PG1DE
NOMESCO Finland
Other extensive ultrasound examination of artery
3.1
10.9
46
155
E10.5
ICD-10 Finland
Type 1 diabetes mellitus, With peripheral circulatory complications
18.1
10.8
16
9
SPAT1262
SPAT
Handing over of treatment supplies
2.0
10.7
142
802
A10BH05
ATC
linagliptin; oral
2.7
10.7
61
242
XF655
NOMESCO Finland
Measurement of heart muscle perfusion with exercise
3.6
10.7
35
100
C01DA08
ATC
isosorbide dinitrate; oral, oral aerosol, sublingual, transdermal
1.7
10.7
266
1823
XG470
NOMESCO Finland
Measurement of diffusion capastity of the lungs
4.2
10.7
28
68
Z95.1
ICD-10 Finland
Presence of aortocoronary bypass graft
2.6
10.5
62
250
ZXE40
NOMESCO Finland
More than seven and less than nine hours
4.6
10.5
25
56
AP1
HP
Catheterization of the left side of the heart
4.2
10.5
28
69
WX203
NOMESCO Finland
Infraclavicular plexus blockade
5.0
10.3
22
45
C09BA02
ATC
enalapril and diuretics; systemic
2.2
10.3
88
421
E87.5
ICD-10 Finland
Hyperkalaemia
3.8
10.2
31
84
XG412
NOMESCO Finland
Flow-volume spirometry with bronchospasmolysis
3.1
10.2
44
150
L89
ICD-10 Finland
Decubitus ulcer and pressure area
4.0
10.2
29
75
N08.39
ICD-10 Finland
Glomerular disorders in diabetes mellitus microalbuminuria
13.4
10.2
17
13
N18.5
ICD-10 Finland
Chronic kidney disease, stage 5
13.4
10.2
17
13
Z49.2
ICD-10 Finland
Other dialysis
13.4
10.2
17
13
H05BX01
ATC
cinacalcet; oral
13.4
10.2
17
13
I21.9
ICD-10 Finland
Acute myocardial infarction, unspecified
3.0
10.1
45
156
I21.09
ICD-10 Finland
Acute transmural myocardial infarction of anterior wall
3.8
10.1
31
85
XF603
NOMESCO Finland
Direct intraarterial blood pressure measurement
3.1
10.0
43
146
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
2.0
9.9
122
671
JN3AA
NOMESCO Finland
Abdominal X-ray examination without contrast
2.9
9.9
48
175
C09AA01
ATC
captopril; oral
3.6
9.9
32
91
C03EB01
ATC
furosemide and potassium-sparing agents; systemic
2.4
9.7
71
317
NHQ40
NOMESCO Finland
Amputation of toe
4.3
9.7
25
60
PH1AE
NOMESCO Finland
Ultrasound examination of upper extremity veins
5.4
9.7
19
36
J01FF01
ATC
clindamycin; systemic
1.8
9.6
182
1148
WW200
NOMESCO Finland
Immunization
4.5
9.6
23
52
25000
ICD-8 Finland
Diabetes mellitus, Sine complicatione
3.3
9.6
36
113
Z3231
NOMESCO Finland
Registered nurse
1.7
9.5
202
1317
GA1AE
NOMESCO Finland
Ultrasound examination of thorax
3.8
9.4
28
75
H3600, E113,
ICD-10 Finland
5.2
9.4
19
37
E10.9
ICD-10 Finland
Type 1 diabetes mellitus, Without complications
3.7
9.3
29
80
81
HP
Angiography of the heart and coronary arteries
2.2
9.3
86
425
AA1
HP
Conventional CABG
3.3
9.3
34
105
WX890
NOMESCO Finland
Intesive care monitoring
7.4
9.3
21
29
R50.9
ICD-10 Finland
Fever, unspecified
2.0
9.3
111
604
I34.00
ICD-10 Finland
Mitral (valve) incompetence NOS or of specified cause, except rheumatic
3.8
9.2
28
76
K65.0
ICD-10 Finland
Acute peritonitis
5.1
9.1
19
38
S97
ICPC
Chronic ulcer skin
2.5
9.1
61
262
FMD10
NOMESCO Finland
Replacement of aortic valve using biological prosthesis
3.9
9.0
26
68
I21.40
ICD-10 Finland
Acute subendocardial infarction no detected stenosis of the coronary artery
2.9
9.0
42
150
CKC10
NOMESCO Finland
Local photocoagulation of retina
3.8
9.0
27
73
A98
ICPC
Health maint/preventive medicine
0.6
8.9
421
4999
PG5DE
NOMESCO Finland
Ultrasound examination of injection gate to artery or vein with Doppler method
24.3
8.9
12
5
B05DB
ATC
Hypertonic solutions
12.7
8.9
15
12
NHQ30
NOMESCO Finland
Amputation of foot, transmetatarsal
12.7
8.9
15
12
A07AA09
ATC
vancomycin; oral
6.9
8.9
21
31
C02EA02, ,
ATC
2.4
8.8
62
273
J01MA14
ATC
moxifloxacin; systemic
2.3
8.7
71
333
E11.3
ICD-10 Finland
Type 2 diabetes mellitus, with ophthalmic complications
3.1
8.7
36
120
B05DA
ATC
Isotonic solutions
11.8
8.6
15
13
JAK10
NOMESCO Finland
Laparotomy and insertion of peritoneal dialysis catheter
16.5
8.6
13
8
A10AD01
ATC
insulin (human); parenteral
3.4
8.6
30
90
I21.01
ICD-10 Finland
Acute transmural myocardial infarction of anterior wall
4.4
8.4
21
49
M01AH05
ATC
etoricoxib; oral
0.6
8.4
174
2529
213
Kela drug reimbursment
Fat metabolism disorder associated with chronic coronary artery disease
2.0
8.3
101
552
C10AA05
ATC
atorvastatin; oral
1.6
8.2
302
2249
I15.1
ICD-10 Finland
Hypertension secondary to other renal disorders
7.7
8.2
18
24
WX408
NOMESCO Finland
General anesthesy, balanced
1.7
8.2
169
1088
A10BH01
ATC
sitagliptin; oral
2.1
8.2
83
425
J96.1
ICD-10 Finland
Chronic respiratory failure
3.3
8.1
30
93
Z2221
NOMESCO Finland
Medical doctor
1.7
8.1
182
1198
SPAT1255
SPAT
Intravenous administration of medicine
2.3
8.1
59
264
KH1AE
NOMESCO Finland
Urinary tract ultrasound examination
2.4
8.0
56
245
E10.6
ICD-10 Finland
Type 1 diabetes mellitus, With other specified complications
22.3
8.0
11
5
PBL09
NOMESCO Finland
Construction of arteriovenous fistula from brachial artery
22.3
8.0
11
5
H02AB06
ATC
prednisolone; systemic
1.6
8.0
321
2436
K77
ICPC
Heart failure
3.1
8.0
34
115
AN2
HP
Balloon angioplasty, including several vessels
3.1
8.0
34
115
I21.4
ICD-10 Finland
Acute subendocardial myocardial infarction
3.8
8.0
24
65
A10AB04
ATC
insulin lispro; parenteral
3.7
7.9
25
70
177
Kela drug reimbursment
Insulin glargine 300 U / ml
4.3
7.8
20
48
T81.0
ICD-10 Finland
Haemorrhage and haematoma complicating a procedure, not elsewhere classified
2.4
7.7
52
224
T90
ICPC
Diabetes non-insulin dependent
1.7
7.7
170
1112
E10.00
ICD-10 Finland
Insulin-dependent diabetes diabetic hypoglycemic coma
12.0
7.6
13
11
XFP20
NOMESCO Finland
Check up of cardiac pacemaker
2.1
7.6
79
408
E10.3
ICD-10 Finland
Type 1 diabetes mellitus, With ophthalmic complications
6.3
7.6
19
31
207
Kela drug reimbursment
Chronic arrhythmias
1.7
7.5
153
978
H3601, E113,
ICD-10 Finland
3.7
7.5
23
63
I21.00
ICD-10 Finland
Acute transmural myocardial infarction of anterior wall
3.4
7.4
26
78
E66.8
ICD-10 Finland
Other obesity
3.3
7.3
27
84
I21.19
ICD-10 Finland
Acute transmural myocardial infarction of inferior wall
3.9
7.3
21
55
J01EE01
ATC
sulfamethoxazole and trimethoprim; systemic
2.4
7.3
51
224
I11.9
ICD-10 Finland
Hypertensive heart disease without (congestive) heart failure
2.3
7.2
54
245
PBM10
NOMESCO Finland
Closure of arteriovenous fistula of radial artery
30.3
7.2
9
*
A04.7
ICD-10 Finland
Enterocolitis due to Clostridium difficile
2.9
7.1
34
123
E10.1
ICD-10 Finland
Type 1 diabetes mellitus, With ketoacidosis
20.2
7.1
10
5
PD4BC
NOMESCO Finland
Extensive arterigography of lower extremity with X-ray
3.8
7.1
21
56
I21.90
ICD-10 Finland
Myocardial infarction (acute) UNS no detected stenosis of the coronary artery
2.9
7.0
32
113
Z02.4
ICD-10 Finland
Examination for driving licence
0.5
7.0
87
1470
R4110
NOMESCO Finland
Physiotherapy
1.6
7.0
179
1214
R41.0
ICD-10 Finland
Disorientation, unspecified
2.7
7.0
38
148
H3601, E103,
ICD-10 Finland
13.9
6.9
11
8
I20.99
ICD-10 Finland
Angina pectoris, unspecified
2.0
6.9
81
437
I10
ICD-10 Finland
Essential (primary) hypertension
1.5
6.9
457
3827
C08DB01
ATC
diltiazem; oral
2.0
6.9
71
366
JN4AD
NOMESCO Finland
Body CT examination
2.1
6.9
70
359
11
HP
Coronary artery bypass surgery
2.7
6.8
36
138
KA2AT
NOMESCO Finland
Biopsy of transplanted kidney with ultrasound guidance
40.4
6.8
8
*
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
2.0
6.7
75
397
3AC01, ,
NOMESCO Finland
7.3
6.7
15
21
KA1AE
NOMESCO Finland
Kidney ultrasound examination
3.1
6.7
27
89
AN3
HP
Balloon angioplasty and metallic stent
2.7
6.7
34
128
PE1AT
NOMESCO Finland
Femoral artery PTA
4.1
6.6
18
45
J44.8
ICD-10 Finland
Other specified chronic obstructive pulmonary disease
1.7
6.6
119
733
I33.0
ICD-10 Finland
Acute and subacute infective endocarditis
7.9
6.6
14
18
XF404
NOMESCO Finland
Ambulatory ECG
2.0
6.6
73
385
H36.00
ICD-10 Finland
Diabetic background retinopathy
4.2
6.6
17
41
B03XA01
ATC
erythropoietin; parenteral
4.2
6.6
17
41
UGC12
NOMESCO Finland
Flexible bronchoscopy
2.1
6.5
66
337
A10AE06
ATC
insulin degludec; parenteral
3.3
6.5
24
75
FXG00
NOMESCO Finland
Insertion and use of IABP
14.5
6.4
10
7
C10AA03
ATC
pravastatin; oral
2.0
6.3
65
334
SPAT1148
SPAT
Treatment of chronic ulcer or burn
1.7
6.3
113
695
ZXE90
NOMESCO Finland
More than 22 hours
6.0
6.3
16
27
B01AC06
ATC
acetylsalicylic acid; oral
2.1
6.3
57
279
I20.00
ICD-10 Finland
Unstable angina
2.5
6.3
40
168
321
Kela drug reimbursment
Paricalcitol and cinacalcet
9.4
6.3
12
13
FN1BT
NOMESCO Finland
Extensive endovascular dilatation of coronary (PTCA) arteries
3.1
6.3
26
87
ZXD00
NOMESCO Finland
Emergency procedure
3.1
6.3
26
87
ZST00
NOMESCO Finland
Procedure related to previous procedure classified in chapter T
+∞
6.3
6
*
C07AB03
ATC
atenolol; systemic
2.0
6.2
68
357
J44.0
ICD-10 Finland
Chronic obstructive pulmonary disease with acute lower respiratory infection
2.1
6.2
58
287
M10.9
ICD-10 Finland
Gout, unspecified
2.0
6.2
64
329
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.6
6.2
198
1409
TQW11
NOMESCO Finland
Vacuum treatment of wound
3.7
6.2
19
52
J01MA12
ATC
levofloxacin; systemic
1.6
6.2
147
975
QDG20
NOMESCO Finland
Operation for chronic ulcer or fistula of skin of lower limb
6.4
6.2
15
24
CKC15
NOMESCO Finland
Panretinal photocoagulation
5.8
6.2
16
28
WW200, ,
SPAT
0.4
6.2
38
819
Z71.3
ICD-10 Finland
Dietary counselling and surveillance
2.9
6.2
28
99
R07.4
ICD-10 Finland
Chest pain, unspecified
1.6
6.1
190
1343
I81
ICD-10 Finland
Portal vein thrombosis
7.8
6.1
13
17
JAH00
NOMESCO Finland
Laparotomy
2.8
6.1
30
111
WW502
NOMESCO Finland
Autotransfusion
8.7
6.1
12
14
N25.8
ICD-10 Finland
Other disorders resulting from impaired renal tubular function
10.1
6.0
11
11
AN4
HP
Balloon angioplasty and drug eluding stent
2.6
6.0
33
129
TJD00
NOMESCO Finland
Insertion of nasogastric or naso-gastroduodenal tube
5.6
6.0
16
29
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
194
501
4.94
71.75
20.0
6.4
14.99
11.52
mmol/l
6.04
187
471
222
721
4.02
59.65
18.2
4.9
1.20
1.03
mmol/l
8.37
213
663
204
657
3.95
55.01
13.4
6.4
5.22
5.09
kpa
0.84
189
622
203
658
3.91
54.15
13.5
6.3
10.04
11.43
kpa
5.03
187
623
202
660
3.87
53.17
13.5
6.4
2.06
1.42
mmol/l
0.89
154
507
221
853
3.30
44.00
5.7
3.1
0.84
0.81
mmol/l
1.66
211
794
176
599
3.57
42.71
14.6
6.5
93.76
95.04
%
1.74
167
569
164
566
3.46
38.63
8.8
3.6
2.10
2.09
mmol/l
0.01
136
450
210
843
3.11
38.49
6.7
2.4
2.15
2.26
g/l
1.74
196
766
201
794
3.13
37.80
7.0
2.4
20.44
21.60
%
0.33
159
681
162
569
3.39
36.98
8.8
3.6
5.82
5.82
kpa
0.01
150
547
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
88
208
4.68
35.04
4.0
2.4
0.29
0.33
u/ml
0.69
55
120
212
916
2.87
33.45
6.8
2.4
10.71
11.89
umol/l
0.86
203
840
47
63
7.91
33.44
8.3
5.5
371.33
224.00
iu/ml
—
12
8
117
376
3.52
30.36
17.3
5.5
25.14
24.35
mmol/l
0.95
112
353
124
414
3.41
30.31
8.9
3.7
194.27
95.11
ng/l
2.95
114
353
146
573
2.95
26.95
5.6
3.1
548.59
253.17
ng/l
5.07
134
529
83
248
3.65
23.85
3.3
1.9
6.88
2.89
ug/l
0.44
77
205
88
279
3.46
23.10
9.7
3.8
24.13
24.05
mmol/l
0.08
83
271
90
295
3.35
22.39
11.1
8.9
24.15
24.70
mmol/l
0.53
82
285
56
132
4.52
22.20
22.4
4.9
104.44
104.86
mmol/l
0.18
50
118
219
1142
2.32
22.05
8.1
4.1
416.85
231.23
ng/l
0.82
198
984
101
361
3.09
21.75
7.3
3.1
112.69
125.03
g/l
6.37
96
351
153
683
2.58
21.65
2.1
1.7
—
—
—
0
0
120
480
2.80
21.07
6.4
2.9
5.53
4.35
kpa
4.06
109
459
79
248
3.46
21.01
16.8
3.9
1.89
1.58
%
2.71
69
231
79
249
3.44
20.88
16.9
4.0
0.91
0.93
%
0.09
71
232
147
660
2.55
20.47
5.6
3.6
258.09
244.69
u/l
0.68
138
622
88
301
3.19
20.37
2.4
1.7
1.61
1.55
g/l
0.22
79
263
46
99
4.90
20.34
1.5
1.6
—
—
—
0
0
151
689
2.51
20.31
2.2
1.7
—
—
—
0
0
190
983
2.27
19.12
2.4
1.7
—
—
—
0
0
175
880
2.31
18.81
3.9
1.9
30.66
30.07
s
0.69
168
844
43
94
4.80
18.66
1.5
1.6
—
—
—
0
0
27
38
7.34
18.32
1.6
1.3
—
—
—
0
0
27
38
7.34
18.32
1.6
1.3
—
—
—
0
0
33
59
5.81
17.87
1.6
1.4
—
—
—
0
0
33
59
5.81
17.87
1.6
1.4
—
—
—
0
0
105
429
2.70
17.55
2.2
1.7
—
—
—
0
0
51
135
3.99
17.35
5.6
2.4
2.53
1.88
mg/l
3.82
46
120
36
72
5.21
17.30
1.4
1.5
—
—
—
0
0
83
306
2.94
16.81
7.2
3.2
24.57
25.03
mmol/l
0.41
78
297
89
351
2.75
15.89
7.5
3.5
1.65
1.99
mmol/l
0.33
68
256
20
7
29.32
15.25
14.9
11.4
5.38
6.81
mmol/l
—
20
7
108
478
2.48
15.24
12.9
6.6
1.34
1.47
mmol/l
0.46
102
466
26
44
6.09
14.87
1.2
1.1
—
—
—
0
0
91
379
2.60
14.56
7.7
3.3
5.16
5.12
kpa
0.15
91
362
143
738
2.17
14.06
5.1
2.3
2.24
1.78
%
3.37
129
650
29
60
4.99
13.41
1.3
1.5
—
—
—
0
0
113
541
2.29
13.30
3.9
2.6
6.57
5.78
ug/l
0.31
103
458
108
508
2.33
13.24
3.2
2.7
64.18
65.66
g/l
1.04
99
447
18
8
23.02
12.94
7.4
7.1
—
—
—
0
0
30
66
4.70
12.92
1.4
1.5
—
—
—
0
0
56
196
3.01
12.40
4.9
3.7
89.37
95.09
mg/l
0.06
46
159
56
197
3.00
12.29
4.9
3.7
67.27
33.85
mg/l
3.03
46
162
233
1499
1.82
11.90
3.2
2.2
3.14
3.20
mg/l
0.14
214
1259
283
1935
1.77
11.73
6.6
3.2
5642.83
2201.65
ng/l
6.70
260
1674
36
99
3.77
11.63
1.5
1.4
24.87
29.52
g/l
1.46
30
90
27
60
4.64
11.50
1.6
1.6
—
—
—
0
0
112
579
2.11
10.80
4.4
2.8
7.86
9.45
umol/l
0.69
95
506
49
173
2.97
10.69
4.0
3.2
0.90
0.88
nmol/l
0.09
39
135
32
86
3.85
10.68
1.6
1.3
—
—
—
0
0
46
157
3.06
10.64
1.8
1.5
—
—
—
0
0
361
2693
1.69
10.58
26.0
6.3
1.18
1.21
mmol/l
11.48
320
2261
32
89
3.72
10.18
8.3
2.1
72.79
59.64
%
2.50
32
89
166
1007
1.84
10.03
3.3
1.7
1.71
1.37
mg/l
0.85
140
798
287
2037
1.68
9.99
6.6
2.7
245.32
157.50
ug/l
2.63
273
1832
31
88
3.64
9.59
1.6
1.3
607.64
1440.26
e6/l
1.82
22
62
26
65
4.11
9.57
1.6
1.2
—
—
—
0
0
50
191
2.74
9.46
1.8
1.2
—
—
—
0
0
367
2803
1.64
9.41
31.4
19.4
1.44
1.39
inr
0.38
100
788
28
75
3.84
9.40
1.6
1.3
31446.94
29666.73
e6/l
0.04
18
45
25
62
4.14
9.30
1.7
1.1
313.95
294.06
u/ml
0.09
19
36
29
81
3.69
9.18
1.2
1.2
—
—
—
0
0
54
219
2.58
9.09
2.9
2.5
10.44
10.19
g/l
0.14
46
186
351
4354
0.62
9.07
44.1
16.6
55.33
72.12
ml/min/173m2
19.45
301
3639
327
2447
1.62
8.97
22.2
5.6
1.18
1.21
mmol/l
10.70
307
2195
56
234
2.51
8.87
2.8
2.4
4.03
3.56
g/l
1.37
49
203
56
235
2.50
8.79
2.8
2.4
—
—
—
0
0
56
235
2.50
8.79
2.8
2.4
8.06
7.46
g/l
1.30
49
203
53
218
2.54
8.67
2.9
2.5
3.14
3.08
g/l
0.15
46
186
27
75
3.70
8.62
1.4
1.7
—
—
—
0
0
318
2388
1.60
8.44
13.4
4.5
31.69
34.43
g/l
13.82
305
2198
294
2173
1.60
8.30
9.9
5.1
63.27
58.95
%
6.87
282
2023
42
160
2.73
8.01
1.5
2.0
32.30
38.59
u/l
0.96
34
140
297
2217
1.58
7.95
9.9
5.3
21.09
25.57
%
9.59
285
2062
438
5103
0.63
7.82
65.8
25.4
120.67
132.12
g/l
31.92
429
4988
438
5101
0.63
7.78
66.7
25.3
36.16
39.10
%
11.76
370
4679
438
5101
0.63
7.78
65.3
25.2
4.09
4.37
e12/l
17.89
424
4926
25
71
3.61
7.75
1.2
1.2
—
—
—
0
0
438
5099
0.63
7.73
65.5
25.2
235.74
237.97
e9/l
0.25
426
4944
91
502
1.93
7.25
2.8
2.1
0.20
0.20
g/l
0.02
84
456
35
128
2.82
7.21
1.5
1.3
—
—
—
0
0
20
51
4.00
7.19
1.4
1.6
—
—
—
0
0
13
14
9.43
6.80
3.5
1.7
86.46
97.86
%
0.38
13
14
35
134
2.69
6.64
1.5
1.2
—
—
—
0
0
35
134
2.69
6.64
1.5
1.2
—
—
—
0
0
219
1581
1.56
6.51
4.7
2.5
63.56
59.97
u/l
0.19
206
1463
10
7
14.46
6.41
1.0
1.0
—
—
—
0
0
208
1489
1.56
6.40
4.5
2.9
42.15
34.80
u/l
0.34
195
1419
384
4524
0.67
6.31
6.1
4.9
6.59
6.11
mmol/l
4.93
343
4024
370
4390
0.67
6.31
5.7
4.5
1.22
1.43
mmol/l
17.82
343
3933
336
2675
1.48
6.20
9.8
5.9
12.80
12.26
umol/l
0.30
325
2524
80
446
1.89
6.17
3.3
2.5
145.33
33.59
u/l
0.49
69
376
21
62
3.46
6.17
1.3
1.5
—
—
—
0
0
191
1352
1.56
6.14
5.0
2.7
6675.99
8428.74
umol/l
0.18
176
1151
45
202
2.31
6.14
3.2
2.8
0.76
0.86
g/l
0.08
39
169
391
4578
0.68
6.10
6.3
5.1
2.22
2.54
mmol/l
11.31
362
4107
12
14
8.69
6.07
1.1
1.1
—
—
—
0
0
428
4918
0.67
5.97
20.8
10.6
28.13
24.74
u/l
1.28
411
4697
68
365
1.95
5.87
2.0
1.5
—
—
—
0
0
159
2214
0.64
5.84
3.7
5.4
2.49
3.57
ug/l
1.31
135
1950
16
31
5.25
5.72
1.1
1.1
—
—
—
0
0
380
4440
0.69
5.54
5.7
4.6
4.01
4.40
mmol/l
11.52
353
4017
217
1612
1.50
5.50
6.1
3.7
47.19
9.82
mg/mmol
5.18
176
1020
121
1766
0.62
5.39
3.4
4.6
24.16
21.58
%
0.86
60
902
42
194
2.24
5.39
2.7
2.8
—
—
—
0
0
41
191
2.22
5.16
3.5
2.6
34.13
37.00
g/l
2.17
34
159
206
1540
1.47
4.98
5.3
3.0
6.19
7.11
mmol/l
3.18
185
1249
438
4953
0.70
4.97
63.3
21.0
4.08
4.01
mmol/l
4.02
426
4803
78
1244
0.58
4.92
2.3
3.2
1.07
0.83
ug/l
0.64
56
859
438
4945
0.70
4.84
61.5
20.9
138.87
139.55
mmol/l
5.20
425
4794
365
4245
0.71
4.76
5.3
4.1
1.51
1.25
mmol/l
6.64
336
3777
15
34
4.48
4.76
1.2
1.6
—
—
—
0
0
5
227
0.21
4.63
1.0
1.8
—
—
—
0
0
167
1222
1.48
4.44
4.6
2.7
5.14
5.05
e6/l
0.06
154
1102
253
2009
1.40
4.30
6.0
3.4
—
—
—
0
0
29
127
2.34
4.24
1.8
1.6
—
—
—
0
0
14
34
4.18
4.22
1.4
1.3
—
—
—
0
0
324
2693
1.37
4.13
13.5
8.2
4.98
4.34
e9/l
4.62
290
2337
65
386
1.75
4.13
2.1
1.6
—
—
—
0
0
10
18
5.61
3.98
2.0
1.8
12202.00
84083.00
e6/l
—
5
13
18
64
2.86
3.98
3.3
2.5
—
—
—
0
0
91
602
1.59
3.84
5.8
4.0
—
—
—
0
0
13
34
3.87
3.70
1.7
1.6
—
—
—
0
0
13
34
3.87
3.70
1.5
1.3
—
—
—
0
0
210
1653
1.38
3.66
3.0
2.1
209.08
282.57
u/l
0.66
197
1536
361
3095
1.34
3.59
15.8
4.7
8.07
6.89
mmol/l
10.95
346
2913
13
36
3.66
3.50
1.8
1.6
—
—
—
0
0
164
1252
1.40
3.40
10.5
3.9
77.68
83.20
%
1.70
158
1222
198
1566
1.37
3.31
5.3
3.3
0.78
0.61
e6/l
0.39
167
1215
129
948
1.44
3.31
4.0
2.9
1.38
1.24
e6/l
0.16
75
556
216
1733
1.35
3.29
6.2
3.4
100.97
119.14
e6/l
0.11
185
1358
32
164
1.99
3.23
1.8
1.5
—
—
—
0
0
14
49
2.89
3.20
1.9
2.6
—
—
—
0
0
124
913
1.43
3.14
5.0
3.1
2.37
2.30
e6/l
0.05
72
525
159
1223
1.39
3.14
5.1
2.5
—
—
—
0
0
10
25
4.04
3.09
1.5
1.7
—
—
—
0
0
10
25
4.04
3.09
1.1
1.2
—
—
—
0
0
13
41
3.21
3.06
1.3
1.7
—
—
—
0
0
429
4731
0.76
3.02
48.2
17.4
30.83
27.34
mg/l
1.47
407
3917
10
26
3.88
2.98
1.5
1.7
—
—
—
0
0
380
4251
0.77
2.95
5.7
4.5
2.18
2.01
mu/l
1.55
351
3763
21
97
2.20
2.79
1.9
1.4
—
—
—
0
0
271
2292
1.29
2.76
5.1
2.7
—
—
—
0
0
396
4386
0.78
2.71
10.5
6.3
45.97
41.17
mmol/mol
10.09
365
3987
20
92
2.21
2.69
1.4
1.5
2.06
6.78
iu/l
—
5
22
13
49
2.68
2.63
1.3
1.1
—
—
—
0
0
6
11
5.49
2.54
1.0
1.0
1438.50
1687.73
miu/ml
—
6
11
(40770918) von Willebrand factor (vWf).activity actual/normal in Platelet poor plasma by Immunoassay
6
11
5.49
2.54
3.3
3.5
172.50
115.18
%
—
6
11
7
16
4.40
2.48
1.4
1.3
—
—
—
0
0
57
378
1.55
2.44
4.9
3.0
39.36
58.23
ml/min/173m2
3.41
33
171
16
70
2.31
2.42
5.1
2.0
31.44
32.96
pg
0.77
16
70
(3011547) Coagulation factor VII activity actual/normal in Platelet poor plasma by Coagulation assay
5
8
6.28
2.37
1.6
1.1
109.20
106.00
%
—
5
8
38
599
0.61
2.28
6.1
4.7
30.96
32.55
%
0.46
28
391
10
34
2.97
2.28
1.8
1.7
—
—
—
0
0
10
34
2.97
2.28
1.5
1.6
—
—
—
0
0
10
34
2.97
2.28
1.8
1.7
—
—
—
0
0
10
34
2.97
2.28
1.8
1.7
—
—
—
0
0
9
29
3.13
2.23
2.6
1.7
—
—
—
0
0
10
35
2.88
2.21
2.5
2.6
—
—
—
0
0
8
24
3.36
2.18
1.9
1.5
18.88
6.42
u/l
—
8
19
10
36
2.80
2.14
1.4
1.7
—
—
—
0
0
15
68
2.23
2.12
1.7
1.7
—
—
—
0
0
13
56
2.34
2.05
1.4
1.1
2.43
7.36
u/ml
—
7
25
15
69
2.20
2.05
1.2
1.1
—
—
—
0
0
31
190
1.66
1.87
1.2
1.2
74.20
154.09
iu/ml
1.09
12
67
6
17
3.55
1.84
1.2
1.1
—
—
—
0
0
156
1296
1.26
1.75
2.0
1.8
1300.58
1185.67
nmol/l
0.61
130
972
5
13
3.86
1.71
1.4
1.0
—
—
—
0
0
5
13
3.86
1.71
1.4
1.0
—
—
—
0
0
6
19
3.17
1.66
1.2
1.2
11.33
25.82
%
—
6
11
9
189
0.47
1.63
1.2
1.0
—
—
—
0
0
5
14
3.59
1.61
1.2
1.1
—
—
—
0
0
10
43
2.34
1.59
2.6
1.9
1.04
13370.65
u/l
—
5
11
170
1442
1.23
1.58
1.8
1.6
18.65
20.09
nmol/l
0.56
150
1217
(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
6
20
3.01
1.58
1.3
1.1
—
—
—
0
0
19
107
1.80
1.55
1.6
1.5
—
—
—
0
0
11
51
2.17
1.51
1.3
1.2
2.00
2.06
u/ml
—
5
16
6
21
2.87
1.50
1.5
1.7
—
—
—
0
0
6
21
2.87
1.50
1.5
1.7
—
—
—
0
0
33
219
1.53
1.48
12.6
4.0
24.74
24.95
mmol/l
0.14
33
206
12
59
2.05
1.44
2.6
1.4
—
—
—
0
0
12
59
2.05
1.44
2.5
1.4
—
—
—
0
0
17
95
1.81
1.44
1.3
1.1
47.48
48.07
u/l
0.01
12
78
221
1947
1.19
1.39
3.7
2.2
74.22
78.40
nmol/l
1.31
200
1685
7
29
2.43
1.39
1.0
1.0
—
—
—
0
0
32
215
1.51
1.37
3.6
1.7
—
—
—
0
0
6
23
2.62
1.37
4.0
2.7
—
—
—
0
0
6
23
2.62
1.37
1.2
2.1
—
—
—
0
0
6
23
2.62
1.37
4.0
2.7
—
—
—
0
0
47
632
0.73
1.33
16.1
8.8
—
—
—
0
0
9
43
2.11
1.30
1.1
1.2
—
—
—
0
0
6
24
2.51
1.30
1.7
1.0
—
—
—
0
0
6
24
2.51
1.30
1.7
1.0
—
—
—
0
0
23
145
1.60
1.30
2.3
2.3
336.76
107.82
ug/min
0.47
15
87
13
69
1.90
1.29
2.5
2.0
88.31
89.12
%
0.20
13
69
46
337
1.39
1.28
7.0
3.0
0.21
0.33
e6/l
0.67
46
332
364
3911
0.86
1.26
55.8
20.5
15.46
15.42
%
0.07
353
3837
6
25
2.41
1.24
2.0
1.2
—
—
—
0
0
6
25
2.41
1.24
2.0
1.2
—
—
—
0
0
9
45
2.01
1.23
15.8
3.2
400.00
342.05
umol/l
—
9
39
10
49
2.05
1.22
1.2
1.1
1.85
1.59
g/l
—
10
43
8
37
2.17
1.21
2.0
2.1
—
—
—
0
0
14
79
1.79
1.17
1.1
1.1
—
—
—
0
0
11
57
1.94
1.17
2.7
1.4
—
—
—
0
0
0
36
0.00
1.14
0.0
3.4
—
—
—
0
0
207
1843
1.17
1.14
5.6
3.2
2.32
2.35
mmol/l
1.60
189
1582
18
112
1.62
1.09
1.6
1.5
—
—
—
0
0
5
21
2.39
1.09
1.6
1.4
—
—
—
0
0
5
21
2.39
1.09
1.2
1.1
—
—
—
0
0
11
59
1.88
1.07
2.6
1.4
—
—
—
0
0
11
59
1.88
1.07
2.6
1.4
—
—
—
0
0
33
238
1.40
1.04
3.6
1.8
—
—
—
0
0
11
60
1.85
1.03
2.6
1.4
—
—
—
0
0
7
35
2.01
1.00
2.1
1.5
—
—
—
0
0
7
35
2.01
1.00
2.1
1.5
—
—
—
0
0
7
36
1.95
0.97
1.3
1.1
—
—
—
0
0
0
32
0.00
0.95
0.0
1.5
—
—
—
0
0
0
32
0.00
0.95
0.0
1.5
—
—
—
0
0
0
32
0.00
0.95
0.0
1.5
—
—
—
0
0
246
2251
1.14
0.92
8.4
4.2
157.13
64.83
ng/l
1.33
198
1749
320
3413
0.89
0.87
4.9
3.6
15.08
15.05
pmol/l
0.06
303
2982
8
47
1.71
0.81
2.6
2.4
578.00
566.25
ml
—
8
28
364
3440
1.12
0.77
6.9
5.1
7899.86
2279.34
e6/l
—
7
77
120
1349
0.87
0.73
6.7
4.5
0.00
0.01
estimate
0.50
34
421
5
25
2.01
0.72
3.8
5.0
—
—
—
0
0
250
2323
1.12
0.71
2.5
2.2
90.99
92.01
pmol/l
0.12
144
1230
13
193
0.67
0.70
1.1
1.8
—
—
—
0
0
7
41
1.71
0.70
1.3
1.1
—
—
—
0
0
10
61
1.65
0.68
1.2
1.4
—
—
—
0
0
5
29
1.73
0.64
1.0
1.1
—
—
—
0
0
8
50
1.61
0.61
1.0
1.3
—
—
—
0
0
14
97
1.45
0.59
1.2
1.2
—
23.85
—
0
6
8
55
1.46
0.56
3.6
3.8
—
—
—
0
0
138
1262
1.12
0.53
1.9
1.8
430.71
9510244.16
pmol/l
0.79
125
1020
119
1084
1.12
0.49
5.4
4.8
1.02
1.02
kg/l
0.10
20
175
13
178
0.72
0.49
1.0
1.7
—
—
—
0
0
7
109
0.64
0.49
3.9
3.8
28.00
422.91
u/ml
—
7
101
176
1882
0.91
0.47
6.3
4.6
—
—
—
0
0
265
2780
0.92
0.45
5.2
3.1
72.47
56.44
u/l
1.81
248
2544
5
31
1.62
0.43
1.4
1.4
—
—
—
0
0
8
56
1.43
0.42
1.6
1.3
17.94
26.07
iu/l
—
8
49
11
79
1.40
0.40
1.2
1.4
—
—
—
0
0
11
79
1.40
0.40
2.8
2.7
4.68
4.71
e9/l
0.02
11
79
5
34
1.47
0.40
1.2
1.1
—
—
—
0
0
8
61
1.31
0.39
1.9
1.2
—
—
—
0
0
394
3817
1.07
0.39
15.2
7.3
98.04
82.02
u/l
1.53
375
3549
19
151
1.26
0.38
1.1
1.2
—
—
—
0
0
18
142
1.27
0.38
1.4
1.4
261.18
275.74
ug/g
0.11
11
74
19
153
1.25
0.35
1.1
1.2
—
—
—
0
0
41
468
0.87
0.35
1.4
1.4
—
—
—
0
0
108
1162
0.92
0.34
2.3
1.6
1.64
1.31
mmol/l
2.34
100
955
11
84
1.31
0.30
4.8
3.1
60.55
60.48
%
0.01
11
84
5
71
0.70
0.26
1.6
1.6
642.40
285.82
mu/l
—
5
66
234
2259
1.05
0.24
3.2
2.4
—
—
—
0
0
12
96
1.25
0.24
1.4
1.7
—
—
—
0
0
5
39
1.28
0.23
1.2
1.1
—
—
—
0
0
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
11
134
0.82
0.21
5.9
4.2
20.18
29.94
mg/l
0.80
11
90
0
14
0.00
0.20
0.0
1.7
—
1.23
—
0
14
16
137
1.17
0.19
1.3
1.4
—
—
—
0
0
42
386
1.09
0.18
1.9
1.6
1.68
1.57
%
0.69
35
324
247
2408
1.04
0.17
5.5
4.3
0.00
0.00
estimate
-0.00
49
492
22
197
1.12
0.15
1.1
1.3
—
—
—
0
0
35
374
0.93
0.12
1.4
1.4
—
—
—
0
0
10
86
1.16
0.11
1.0
1.1
—
—
—
0
0
65
623
1.05
0.10
1.2
1.2
135.65
38.01
iu/ml
0.67
24
205
111
1141
0.97
0.10
4.2
3.2
2.49
2.46
mmol/l
0.75
95
979
350
3535
0.98
0.09
5.7
3.9
23.51
14.71
mm/h
11.36
326
3198
6
56
1.07
0.08
1.5
1.3
—
—
—
0
0
6
72
0.83
0.07
1.8
1.2
—
—
—
0
0
7
81
0.86
0.07
1.1
2.0
—
—
—
0
0
61
590
1.04
0.07
3.8
4.2
4.19
33.20
ug/l
1.40
53
500
81
831
0.97
0.07
1.3
1.2
0.81
1.46
u/ml
1.13
17
218
61
591
1.03
0.06
1.3
1.2
6.82
8.72
u/ml
0.18
27
210
246
2435
1.01
0.05
5.5
4.3
0.00
0.00
estimate
-0.00
41
436
242
2404
1.01
0.02
7.6
5.8
0.00
0.00
estimate
-0.00
44
439
11
112
0.98
0.00
1.1
1.3
—
—
—
0
0
0
9
0.00
0.00
0.0
2.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.7
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
6
68
0.88
-0.00
1.2
1.8
235.00
224.90
pmol/l
—
6
62
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.3
—
—
—
0
0
6
67
0.89
-0.00
1.2
1.8
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.7
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint J10_PULMOEDEMA and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| J10_PULMOEDEMA | 3.634 [3.06, 4.32] | < 0.001 |
| Birth year | 0.996 [0.99, 1.01] | 0.435 |
During the follow-up period (1.1.1998 — 31.12.2019), 1992 out of 2704 females with J10_PULMOEDEMA died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| J10_PULMOEDEMA | 4.391 [3.53, 5.47] | < 0.001 |
| Birth year | 0.988 [0.98, 1.0] | 0.011 |
During the follow-up period (1.1.1998 — 31.12.2019), 1713 out of 2356 males with J10_PULMOEDEMA died.
Mortality risk
Mortality risk for people of age
years, who have J10_PULMOEDEMA.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.404% | 0.926% |
| 5 | 2.256% | 4.818% |
| 10 | 5.214% | 12.463% |
| 15 | 10.119% | 22.504% |
| 20 | 17.492% | 35.623% |
Relationships between endpoints
↥Index endpoint: J10_PULMOEDEMA – Pulmonary oedema
GWS hits: 1
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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