No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleNone |
520210 |
2. Check conditionsNone |
520210 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
2837 |
4. Check minimum number of eventsNone |
2837 |
5. Include endpointsNone |
2837 |
6. Filter based on genotype QC (FinnGen only) |
2837 |
Control definitions (FinnGen only)
- Control exclude
- K11_ENERCOLNONINF
Extra metadata
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- K50
- Name in latin
- Morbus Crohn intestini tenuis
Similar endpoints
↥List of similar endpoints to
Crohn's disease of small intestine
based on the number of shared cases.
Similar with more cases:
- Crohn disease
- Inflammatory bowel disease
- Noninfective enteritis and colitis
- Autoimmune diseases related-to ILD
- Autoimmune diseases
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 14329 | 7428 | 6841 |
| Only index persons | 13748 | 7172 | 6576 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.20 | 0.21 | 0.19 |
| Only index persons | 0.26 | 0.26 | 0.25 |
| Median age at first event (years) | |||
| Whole population | 41.93 | 41.13 | 42.78 |
| Only index persons | 41.18 | 40.37 | 42.08 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 2837 | 1632 | 1205 |
| Unadjusted period prevalence (%) | 0.55 | 0.56 | 0.53 |
| Median age at first event (years) | 43.89 | 41.61 | 46.99 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 2551
- Matched controls
- 25509
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
H02AB06
ATC
prednisolone; systemic
5.2
323.3
1731
7383
208
Kela drug reimbursment
Ulcerative colitis and Crohn's disease
+∞
323.0
1999
*
UJF32
NOMESCO Finland
Coloscopy
20.1
323.0
1823
2828
A07EC02
ATC
mesalazine; oral, rectal
320.7
323.0
1398
96
K51.9
ICD-10 Finland
Ulcerative colitis, unspecified
1297.1
323.0
432
*
L01BB02
ATC
mercaptopurine; oral
227.5
323.0
370
19
K51.5
ICD-10 Finland
Left sided colitis
981.2
323.0
341
*
K50.8
ICD-10 Finland
Other Crohn disease
16384.0
323.0
1364
*
UJF30
NOMESCO Finland
Ileoscopy through colon
28.5
323.0
1233
809
L04AX01
ATC
azathioprine; systemic
114.0
323.0
1388
264
L04AB04
ATC
adalimumab; parenteral
31.8
323.0
451
171
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
8.5
323.0
1498
3643
A07EA06
ATC
budesonide; oral, local oral
553.2
323.0
1418
57
JF1CG
NOMESCO Finland
Extensive MRI of small bowel
341.4
323.0
450
16
326
Kela drug reimbursment
Adalimumab, golimumab, infliximab and ustekinumab (intestinal diseases)
+∞
323.0
521
*
UJF92
NOMESCO Finland
Capsular endoscopy
81.8
323.0
720
122
K50.0
ICD-10 Finland
Crohn disease of small intestine
4503599627370496.0
323.0
2550
*
K50.9
ICD-10 Finland
Crohn disease, unspecified
10841.9
323.0
1211
*
K50.1
ICD-10 Finland
Crohn disease of large intestine
+∞
323.0
870
*
K52.9
ICD-10 Finland
Noninfective gastroenteritis and colitis, unspecified
46.4
315.0
388
98
K50
ICD-10 Finland
Crohn disease [regional enteritis]
+∞
297.9
280
*
JF1DG
NOMESCO Finland
Small bowel very extensive MRI with with high intensity magnet
270.2
286.1
288
12
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
4.9
265.4
1162
3747
C10AC01
ATC
colestyramine; oral
24.9
249.9
360
167
P01AB01
ATC
metronidazole; oral, rectal
4.2
249.5
1495
6420
A07EA02
ATC
hydrocortisone; rectal
61.2
229.6
269
49
ZX120
NOMESCO Finland
Intravenous
7.3
222.8
595
1021
J01MA02
ATC
ciprofloxacin; systemic
3.9
221.2
1339
5590
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
3.8
213.4
1388
6098
K51.1
ICD-10 Finland
Ulcerative (chronic) ileocolitis
+∞
208.2
197
*
K51.8
ICD-10 Finland
Other ulcerative colitis
1082.9
207.2
200
*
JF1BD
NOMESCO Finland
Very extensive small bowel CT
87.0
192.9
215
27
A07EC01
ATC
sulfasalazine; oral, rectal
7.0
191.2
520
899
L04AX03
ATC
methotrexate; systemic (immunosuppressants)
6.0
181.0
558
1133
D94
ICPC
Chronic enteritis/ulcerative colitis
381.3
179.9
179
5
H02AB07
ATC
prednisone; oral
5.1
177.8
649
1603
K51.0
ICD-10 Finland
Ulcerative (chronic) pancolitis
+∞
169.7
161
*
JFB20
NOMESCO Finland
Ileocaecal resection
108.8
167.6
182
18
JN3BD
NOMESCO Finland
Extensive abdominal CT
5.4
156.4
523
1153
JFB00
NOMESCO Finland
Partial resection of small intestine
30.0
154.4
210
76
M07.4*K50.9
ICD-10 Finland
Arthropathy in Crohn's disease [regional enteritis]
+∞
152.6
145
*
K56.6
ICD-10 Finland
Other and unspecified intestinal obstruction
14.5
151.8
265
202
JN3AA
NOMESCO Finland
Abdominal X-ray examination without contrast
9.9
147.3
312
354
B03BA03
ATC
hydroxocobalamin; parenteral
8.9
144.1
325
411
K51.3
ICD-10 Finland
Ulcerative (chronic) rectosigmoiditis
1457.9
142.0
137
*
JF1AD
NOMESCO Finland
Small bowel CT
109.2
141.8
154
15
L04AC05
ATC
ustekinumab; parenteral
86.3
138.0
154
19
601
Kela drug reimbursment
Severe malabsorption of nutrients, mainly fats
43.0
132.1
165
41
GD1AA
NOMESCO Finland
Thorax X-ray examination
2.8
129.5
1233
6317
K52.88
ICD-10 Finland
Other specified noninfective gastroenteritis and colitis
61.6
129.0
151
26
4AA12
NOMESCO Finland
NA
271.8
127.3
129
5
O99.6
ICD-10 Finland
Diseases of the digestive system complicating pregnancy, childbirth and the puerperium
50.7
126.5
153
32
A02BC02
ATC
pantoprazole; systemic
2.7
118.8
1744
11327
TPH04
NOMESCO Finland
Cathetrisation of vein
3.3
117.2
735
2803
WX002
NOMESCO Finland
Sedation and analgesia
3.4
116.7
668
2378
4AB02
NOMESCO Finland
NA
181.3
116.4
121
7
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
3.3
107.4
663
2474
UJF45
NOMESCO Finland
Flexible sigmoidoscopy with biopsy
5.3
106.5
352
743
Z04.8
ICD-10 Finland
Examination and observation for other specified reasons
3.8
103.6
507
1573
5552A
ICD-9 Finland
Regional enteritis, Small intestine with large intestine
+∞
98.6
94
*
D50.9
ICD-10 Finland
Iron deficiency anaemia, unspecified
5.4
97.7
319
661
56300
ICD-8 Finland
Chronic enteritis and ulcerative colitis, Regional enteritis
+∞
95.4
91
*
5550A
ICD-9 Finland
Regional enteritis, Small intestine
+∞
93.3
89
*
NK6QA
NOMESCO Finland
Measurement of bone density from tow or more locations with X-ray
5.4
91.8
299
616
107
Kela drug reimbursment
Pernicious anaemia
16.3
89.8
148
96
A06AC01
ATC
ispaghula (psylla seeds); oral
2.8
87.5
686
2949
JFA98
NOMESCO Finland
Other transluminal endoscopic local operation on intestine
14.0
83.3
146
110
JFA38
NOMESCO Finland
Endoscopic dilatation of small intestine
823.9
81.9
80
*
JX1LA
NOMESCO Finland
Kinetic X-ray of alimentary tract with pictures
415.4
81.4
81
*
UJF02
NOMESCO Finland
Peroral enteroscopy
36.9
80.1
103
29
WX302
NOMESCO Finland
Thoracal epidural anesthesy
5.8
77.8
234
436
JFA58
NOMESCO Finland
Endoscopic dilatation of colon
81.0
76.6
86
11
UJF12
NOMESCO Finland
Enteroscopy through intestinal stoma
201.0
75.6
78
*
N02AX02
ATC
tramadol; systemic, rectal
2.2
75.1
1105
6518
B81
ICPC
Anaemia vit B12/folate deficiency
7.1
74.2
190
285
K60.3
ICD-10 Finland
Anal fistula
10.3
73.0
148
151
K56.7
ICD-10 Finland
Ileus, unspecified
14.8
72.5
124
88
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
3.7
69.9
338
1014
K51.2
ICD-10 Finland
Ulcerative (chronic) proctitis
179.8
67.4
70
*
M07.4
ICD-10 Finland
Arthropathy in Crohn disease [regional enteritis]
664.9
66.2
65
*
Z01.8
ICD-10 Finland
Other specified special examinations
2.5
65.5
644
3074
K56.5
ICD-10 Finland
Intestinal adhesions [bands] with obstruction
11.7
65.4
124
111
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
2.9
64.7
448
1739
UJF14
NOMESCO Finland
Enteroscopy of ileoanal anastomosis
139.6
64.2
68
5
N02BE01
ATC
paracetamol; systemic, rectal
2.4
64.0
2172
17873
A02BC03
ATC
lansoprazole; oral
2.3
63.5
763
4016
WX408
NOMESCO Finland
General anesthesy, balanced
2.3
63.4
784
4182
JFB21
NOMESCO Finland
Laparoscopic ileocaecal resection
218.7
62.4
64
*
JH1CG
NOMESCO Finland
Extensive MRI of perianal area
31.3
61.5
82
27
JFB33
NOMESCO Finland
Other resection comprising small intestine and colon
96.8
60.1
66
7
4AA33
NOMESCO Finland
NA
+∞
58.6
56
*
1370
FHL
Colonoscopy, whole colon
93.8
58.1
64
7
JN3AD
NOMESCO Finland
Abdominal CT examination
3.7
57.3
269
782
5551A
ICD-9 Finland
Regional enteritis, Large intestine
+∞
56.5
54
*
A02BC01
ATC
omeprazole; systemic
2.2
55.2
704
3764
A07DA03
ATC
loperamide; oral
6.2
54.9
154
261
L01BA01
ATC
methotrexate; systemic (folic acid analog.)
5.0
53.9
182
385
K21.0
ICD-10 Finland
Gastro-oesophageal reflux disease with oesophagitis
3.2
52.4
302
1026
3042
Kela drug reimbursment
NA
+∞
52.3
50
*
Z93.2
ICD-10 Finland
Ileostomy status
48.8
51.3
62
13
253
Kela drug reimbursment
NA
+∞
51.2
49
*
JAH00
NOMESCO Finland
Laparotomy
6.7
50.2
132
205
J01MA12
ATC
levofloxacin; systemic
2.4
50.2
475
2183
M45
ICD-10 Finland
Ankylosing spondylitis
6.2
49.5
138
232
A02BC05
ATC
esomeprazole; systemic
1.9
49.4
1002
6411
R50.9
ICD-10 Finland
Fever, unspecified
2.5
49.2
429
1885
D64.9
ICD-10 Finland
Anaemia, unspecified
3.4
48.7
256
811
JHA00
NOMESCO Finland
Anal or perianal incision
9.3
47.7
101
112
K83.0
ICD-10 Finland
Cholangitis
13.7
46.3
81
61
K43.9
ICD-10 Finland
Other and unspecified ventral hernia without obstruction or gangrene
4.8
46.2
161
352
3AC01
NOMESCO Finland
NA
11.8
46.0
86
75
D50.0
ICD-10 Finland
Iron deficiency anaemia secondary to blood loss (chronic)
6.3
45.1
124
205
Z71.3
ICD-10 Finland
Dietary counselling and surveillance
3.8
43.7
199
560
K61.0
ICD-10 Finland
Anal abscess
7.2
43.7
109
157
JFA15
NOMESCO Finland
Endoscopic polypectomy in colon
4.8
43.7
153
336
K57.3
ICD-10 Finland
Diverticular disease of large intestine without perforation or abscess
2.5
43.3
383
1687
UJD02
NOMESCO Finland
Gastroscopy
4.3
43.2
168
410
6403
FHL
Ileocal resection
223.7
43.0
44
*
5559X
ICD-9 Finland
Regional enteritis, Unspecified site
+∞
42.8
41
*
JF1AB
NOMESCO Finland
Passage examination of small bowell with X-ray
9.4
42.2
89
98
J01DB01
ATC
cefalexin; oral
2.0
42.0
2091
17737
JFB30
NOMESCO Finland
Right hemicolectomy
12.4
41.7
76
63
JF1CM
NOMESCO Finland
Small bowel extensive MRI with with high intensity magnet
414.0
41.2
41
*
K58.0
ICD-10 Finland
Irritable bowel syndrome with diarrhoea
3.4
41.0
209
645
5562A
ICD-9 Finland
Idiopathic proctocolitis, Ulcerative (chronic) proctitis
+∞
40.7
39
*
K59.1
ICD-10 Finland
Functional diarrhoea
4.1
40.7
166
424
A07EA01
ATC
prednisolone; rectal
65.3
39.2
45
7
56310
ICD-8 Finland
Chronic enteritis and ulcerative colitis, Ulcerative colitis
+∞
38.6
37
*
JF1DM
NOMESCO Finland
Very extensive MRI of small bowel (more than 1.5 T)
382.9
38.1
38
*
202
Kela drug reimbursment
Connective tissue diseases, rheumatoid arthritis and comparable disease
2.5
37.0
320
1387
JFF13
NOMESCO Finland
Terminal enterostomy
69.3
36.0
41
6
N02AJ06
ATC
codeine and paracetamol; systemic
1.7
35.5
948
6447
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.7
35.4
1127
8074
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
1.9
35.0
617
3653
JKE98
NOMESCO Finland
Other transduodenal endoscopic operation on bile duct or ampulla of Vater
10.7
34.9
68
65
H02AB09
ATC
hydrocortisone; systemic
5.5
34.6
106
201
WW200
NOMESCO Finland
Immunization
4.5
34.6
128
298
K92.1
ICD-10 Finland
Melaena
4.0
34.4
145
381
A02BA02
ATC
ranitidine; systemic
2.1
34.4
441
2299
R10.1
ICD-10 Finland
Pain localized to upper abdomen
2.1
34.4
427
2196
K44.9
ICD-10 Finland
Diaphragmatic hernia without obstruction or gangrene
3.1
33.9
200
686
K51
ICD-10 Finland
Ulcerative colitis
93.9
33.8
37
*
L04AA33
ATC
vedolizumab; parenteral
+∞
33.4
32
*
5568X
ICD-9 Finland
Idiopathic proctocolitis, Other ulcerative colitis
+∞
33.4
32
*
M07.5*K51.9
ICD-10 Finland
Arthropathy in ulcerative colitis
+∞
32.4
31
*
A05AA02
ATC
ursodeoxycholic acid; oral
6.7
32.3
84
129
Z98.0
ICD-10 Finland
Intestinal bypass and anastomosis status
26.3
31.9
44
17
JHD30
NOMESCO Finland
Incomplete incision of fistula-in-ano
30.5
31.7
42
14
WVA20
NOMESCO Finland
Medicine administration
5.8
31.3
91
162
4AC05
NOMESCO Finland
NA
+∞
31.3
30
*
JFG40
NOMESCO Finland
Revision of enterostomy or colostomy without laparotomy
38.6
30.3
38
10
K56.0
ICD-10 Finland
Paralytic ileus
13.6
30.0
52
39
ZJX00
NOMESCO Finland
Double balloon technique in gastroenterological endoscopy
41.6
29.9
37
9
JFH10
NOMESCO Finland
Total colectomy and ileostomy
68.8
29.9
34
5
J02AC01
ATC
fluconazole; systemic
1.7
29.8
973
6917
H20.0
ICD-10 Finland
Acute and subacute iridocyclitis
3.6
29.6
138
396
A49.9
ICD-10 Finland
Bacterial infection, unspecified
2.5
29.4
240
1003
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.6
29.3
1043
7578
M09.1*K50.9
ICD-10 Finland
Juvenile arthritis in Crohn's disease [regional enteritis]
+∞
29.2
28
*
D01
ICPC
Abdominal pain/cramps general
2.2
29.1
323
1573
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
2.6
29.1
230
943
JJ2AT
NOMESCO Finland
Biopsy of liver with ultrasound guidance
5.2
28.5
90
177
TPH20
NOMESCO Finland
Insertion of central venous catheter through subclavian or brachiocephalic vein
4.6
28.4
101
226
XJW99
NOMESCO Finland
Other investigative procedure on digestive system
26.4
28.4
39
15
B01AB05
ATC
enoxaparin; parenteral
1.8
28.1
628
3981
6402
FHL
Small bowel resection
64.7
28.0
32
5
K29.3
ICD-10 Finland
Chronic superficial gastritis
4.6
27.9
100
226
JFH30
NOMESCO Finland
Total colectomy, mucosal proctectomy and ileoanal anastomosis without ileostomy
284.5
27.8
28
*
ZX112
NOMESCO Finland
Subcutaneous
5.2
27.5
87
172
K63.1
ICD-10 Finland
Perforation of intestine (nontraumatic)
12.5
27.3
49
40
JAP00
NOMESCO Finland
Freeing of adhesions in the peritoneal cavity
10.2
27.2
54
54
JN1CG
NOMESCO Finland
Extensive MRI examination of upper part of abdomen with high intensity magnet
4.7
26.8
93
203
E0000UV
ATC
NA
1.6
26.7
959
6934
WX402
NOMESCO Finland
General anaesthesia
1.9
26.7
427
2409
5561A
ICD-9 Finland
Idiopathic proctocolitis, Ulcerative (chronic) ileocolitis
+∞
26.1
25
*
L30.9
ICD-10 Finland
Dermatitis, unspecified
1.9
25.9
432
2473
R19.8
ICD-10 Finland
Other specified symptoms and signs involving the digestive system and abdomen
8.0
25.9
59
75
JHD20
NOMESCO Finland
Incision of fistula-in-ano
8.0
25.9
59
75
A06AC51
ATC
ispaghula, combinations; systemic
3.3
25.9
136
429
C05AA08
ATC
fluocortolone; rectal, topical
2.1
25.7
337
1760
JAH01
NOMESCO Finland
Laparoscopy
3.1
25.6
145
482
SPAT1256
SPAT
Intramuscular and subcutaneous injection
1.6
25.5
939
6810
K65.0
ICD-10 Finland
Acute peritonitis
8.4
25.3
56
68
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
2.9
25.0
158
565
WX602
NOMESCO Finland
Repeated or continuing anesthesia shots throug a catheter
2.3
24.8
250
1162
JFA60
NOMESCO Finland
Stricturoplasty in small intestine
252.5
24.7
25
*
R11
ICD-10 Finland
Nausea and vomiting
2.4
24.7
215
927
JFG50
NOMESCO Finland
Laparotomy with revision of enterostomy or colostomy
131.3
24.6
26
*
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
2.2
24.4
264
1265
JHD33
NOMESCO Finland
Completing incision of fistula-in-ano
22.2
24.3
35
16
JAD30
NOMESCO Finland
Repair of incisional hernia using prosthetic material
6.4
24.1
64
102
A04.7
ICD-10 Finland
Enterocolitis due to Clostridium difficile
5.3
24.1
74
142
JFH20
NOMESCO Finland
Proctocolectomy and ileostomy
+∞
24.0
23
*
K29.8
ICD-10 Finland
Duodenitis
11.8
23.9
44
38
K91.2
ICD-10 Finland
Postsurgical malabsorption, not elsewhere classified
87.6
23.7
26
*
Z03.89
ICD-10 Finland
Observation for other suspected diseases and conditions
2.0
23.6
310
1619
D07AC01
ATC
betamethasone; topical
1.6
23.4
761
5319
JEA00
NOMESCO Finland
Appendectomy
2.5
23.2
197
838
UKC02
NOMESCO Finland
Cystoscopy
2.0
23.2
303
1578
WX404
NOMESCO Finland
Intravenous generell anesthesy
1.8
23.0
503
3137
H02AB04
ATC
methylprednisolone; systemic
2.0
22.9
338
1846
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
2.3
22.9
222
1011
K30
ICD-10 Finland
Functional dyspepsia
2.1
22.8
264
1303
D07AB02
ATC
hydrocortisone butyrate; topical
1.6
22.8
656
4431
JL5BG
NOMESCO Finland
MRI examinaiton of bile and pancreas ducts with high intesity magnet
4.3
22.8
85
201
UJK12
NOMESCO Finland
Peroral cholangioscopy
84.2
22.7
25
*
JFG00
NOMESCO Finland
Closure of loop enterostomy without resection
12.7
22.6
40
32
WZC30
NOMESCO Finland
Teaching
2.0
22.4
311
1654
WZB00
NOMESCO Finland
Telephone receipt or other advice
1.6
21.8
736
5174
N03AX16
ATC
pregabalin; oral
1.7
21.7
502
3183
A07AA09
ATC
vancomycin; oral
7.5
21.6
51
69
NK4XE
NOMESCO Finland
Joint ultrasound examination not elsewhere classified
2.5
21.6
181
763
J01AA02
ATC
doxycycline; systemic
1.5
21.4
1775
15276
JH1CM
NOMESCO Finland
Perianal extensive MRI with 3 Tesla magnet
43.7
21.4
26
6
A03FA01
ATC
metoclopramide; systemic, rectal
1.8
21.3
448
2756
UJH02
NOMESCO Finland
Anoscopy
3.2
21.3
117
382
M01AH01
ATC
celecoxib; oral (coxibs)
1.8
21.2
372
2156
WZC00
NOMESCO Finland
Planning of intervention or health care consultation
1.6
20.9
783
5633
6404
FHL
Hemicolectomy on the right
60.5
20.9
24
*
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
1.5
20.8
1164
9169
A03CA02
ATC
clidinium and psycholeptics; oral
2.8
20.8
135
492
Z93
ICD-10 Finland
Artificial opening status
21.7
20.8
30
14
S18
ICPC
Laceration/cut
1.5
20.6
877
6496
NA6BG
NOMESCO Finland
Sacro-iliac joint MRI examination with high intensity magnet
4.3
20.6
77
183
M81.4
ICD-10 Finland
Drug-induced osteoporosis
25.7
20.4
28
11
JN1DG
NOMESCO Finland
Very extensive MRI examination of upper part of abdomen with high intensity magnet
5.4
20.4
62
118
K61.1
ICD-10 Finland
Rectal abscess
18.4
20.4
31
17
6455
FHL
Perianal fistula surgery
18.4
20.4
31
17
J05AB11
ATC
valaciclovir; oral
1.9
20.3
308
1692
TJF80
NOMESCO Finland
Ostomy education
9.7
20.3
41
43
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.5
20.3
1245
9981
B04AD01
ATC
NA
32.8
20.2
26
8
B03BA02
ATC
cyanocobalamin tannin complex; parenteral
13.8
20.0
34
25
7890A
ICD-9 Finland
Other symptoms involving abdomen and pelvis, Abdominal pain
2.7
19.8
141
543
A07EC03
ATC
olsalazine; oral
105.8
19.6
21
*
M05BA04
ATC
alendronic acid; oral
2.6
19.4
147
589
DM1AA
NOMESCO Finland
Paranasal sinuses X-ray examination without contrast
3.1
19.4
108
357
D07AD01
ATC
clobetasol; topical
1.8
19.2
340
1973
JL5SB
NOMESCO Finland
Endoscopic retrograd cholangiopancreaticography
6.8
19.1
48
72
JHW96
NOMESCO Finland
Other operation on anus or perianal tissue
12.3
19.1
34
28
UJF34
NOMESCO Finland
Left colonoscopy
11.4
19.0
35
31
J01FF01
ATC
clindamycin; systemic
1.6
18.9
609
4203
J01FA06
ATC
roxithromycin; oral
1.5
18.9
890
6713
JN3CD
NOMESCO Finland
Abdominal CT examination both without and with contrast
3.4
18.8
91
271
E000001
ATC
NA
1.7
18.8
497
3259
A03FA02
ATC
cisapride; oral, rectal
2.4
18.7
166
723
SPAT1263
SPAT
Sampling
1.5
18.5
976
7530
A06AD11
ATC
lactulose; oral
2.0
18.5
248
1302
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
1.8
18.4
380
2318
E86
ICD-10 Finland
Volume depletion
4.9
18.3
60
125
JFF10
NOMESCO Finland
Loop enterostomy
11.9
18.3
33
28
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
1.7
18.1
403
2514
D11
ICPC
Diarrhoea
1.9
18.0
297
1683
K63.2
ICD-10 Finland
Fistula of intestine
26.9
17.8
24
9
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
2.2
17.7
197
955
1300
FHL
Esophagogastroduodenoscopy (also includes staining)
8.6
17.7
38
45
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
2.3
17.6
164
730
WX110
NOMESCO Finland
Local anesthesy
1.5
17.6
1697
14710
R10.0
ICD-10 Finland
Acute abdomen
3.1
17.1
97
323
K21.9
ICD-10 Finland
Gastro-oesophageal reflux disease without oesophagitis
2.0
16.9
215
1100
JFA96
NOMESCO Finland
Other local operation on intestine
63.7
16.7
19
*
J01DA01
ATC
[U] cefalexin; systemic
1.4
16.7
1446
12208
Y83
ICD-10 Finland
Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
2.2
16.6
166
769
QBB10
NOMESCO Finland
Major dressing of wound of skin of trunk
2.9
16.6
101
355
K76.0
ICD-10 Finland
Fatty (change of) liver, not elsewhere classified
3.6
16.6
76
218
TJJ00
NOMESCO Finland
Percutaneous needle biopsy of liver
16.4
16.5
26
16
XF603
NOMESCO Finland
Direct intraarterial blood pressure measurement
3.4
16.3
81
247
L04AA01
ATC
[U] ciclosporin; systemic
4.8
16.2
54
115
K85
ICD-10 Finland
Acute pancreatitis
5.2
16.2
50
98
JFA70
NOMESCO Finland
Suture of small intestine
16.8
16.1
25
15
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
2.5
16.1
126
516
TJD00
NOMESCO Finland
Insertion of nasogastric or naso-gastroduodenal tube
5.8
16.0
45
79
J01FA10
ATC
azithromycin; systemic
1.4
16.0
1433
12128
K29.7
ICD-10 Finland
Gastritis, unspecified
3.0
15.9
91
306
N02AA05
ATC
oxycodone; systemic
1.9
15.9
239
1307
D01AC20
ATC
imidazoles/triazoles in combination with corticosteroids; topical
1.6
15.8
489
3324
RD210
NOMESCO Finland
NA
3.6
15.8
72
206
B02.9
ICD-10 Finland
Zoster without complication
2.6
15.7
119
477
5586X
ICD-9 Finland
Other non-infective gastro-enteritis and colitis[KROONINEN INFLAMMATOORINEN SUOLISTOSAIRAUS, NUD]
+∞
15.6
15
*
4AA17
NOMESCO Finland
NA
+∞
15.6
15
*
L40.0
ICD-10 Finland
Psoriasis vulgaris
2.7
15.6
109
419
K29.5
ICD-10 Finland
Chronic gastritis, unspecified
3.8
15.5
66
178
K52.80
ICD-10 Finland
(Hemorrhagic) colitis caused by antibiotics
160.9
15.5
16
*
JF1CD
NOMESCO Finland
Extensive small bowel CT
160.9
15.5
16
*
R51.80
ICD-10 Finland
Headache
1.7
15.4
360
2270
A07AA02
ATC
nystatin; oral
2.4
15.4
130
553
A01AB09
ATC
miconazole; local oral
2.1
15.2
184
925
M79.6
ICD-10 Finland
Pain in limb
1.5
15.2
751
5663
1490
FHL
Sigmoideoscopy (fiberscope)
28.8
15.2
20
7
J01.0
ICD-10 Finland
Acute maxillary sinusitis
1.5
15.2
528
3687
Z01.5
ICD-10 Finland
Diagnostic skin and sensitization tests
1.9
15.2
235
1298
M25.5
ICD-10 Finland
Pain in joint
1.5
15.0
624
4531
M54.5
ICD-10 Finland
Low back pain
1.5
15.0
729
5471
D06BX01
ATC
metronidazole; topical
1.9
14.9
232
1285
L02.3
ICD-10 Finland
Cutaneous abscess, furuncle and carbuncle of buttock
3.4
14.8
72
217
D07AC13
ATC
mometasone; topical
1.5
14.8
625
4554
K92.2
ICD-10 Finland
Gastrointestinal haemorrhage, unspecified
3.6
14.8
66
186
WZC20
NOMESCO Finland
Multidisciplinary treatment meeting
2.4
14.8
121
508
SFA10
NOMESCO Finland
Fillning on one surface of tooth
1.4
14.8
1293
10827
R03AC02
ATC
salbutamol; inhalant
1.4
14.7
1195
9873
Z94.4
ICD-10 Finland
Liver transplant status
13.3
14.7
25
19
D07XC01
ATC
betamethasone, combinations; topical
1.8
14.7
253
1451
K80.2
ICD-10 Finland
Calculus of gallbladder without cholecystitis
1.9
14.6
235
1316
D99
ICPC
Disease digestive system other
6.6
14.6
37
57
TPH07
NOMESCO Finland
Cathetrisation of artery
2.0
14.6
200
1058
D07BB04
ATC
hydrocortisone butyrate and antiseptics; topical
1.8
14.6
290
1741
SPAT1153
SPAT
Removal of sutures
1.5
14.5
630
4616
JK3MN
NOMESCO Finland
Bile absorbtion isotope examination
150.8
14.5
15
*
R06.0
ICD-10 Finland
Dyspnoea
1.6
14.4
455
3097
N05CF01
ATC
zopiclone; oral
1.5
14.2
600
4366
UJK02
NOMESCO Finland
ERCP
3.9
14.2
57
147
R4190
NOMESCO Finland
Nutritional therapy
2.7
14.2
100
386
WYA05
NOMESCO Finland
Emergency visit or other similar visit involving procedures
1.4
14.1
1156
9540
WW500
NOMESCO Finland
Blood transfusion
2.8
14.0
92
342
J05AB01
ATC
aciclovir; systemic
1.6
13.9
451
3091
D50.8
ICD-10 Finland
Other iron deficiency anaemias
4.6
13.9
48
107
JFB96
NOMESCO Finland
Other partial excision of intestine
30.2
13.9
18
6
Z01.2
ICD-10 Finland
Dental examination
1.4
13.8
995
8018
K63.8
ICD-10 Finland
Other specified diseases of intestine
23.9
13.8
19
8
K58.9
ICD-10 Finland
Irritable bowel syndrome without diarrhoea
2.7
13.7
93
350
JL5AG
NOMESCO Finland
Simple MRI examinaiton of bile and pancreas ducts with high intesity magnet
6.7
13.7
34
51
SAA02
NOMESCO Finland
Basic examination of mouth
1.4
13.7
1603
14025
JGB50
NOMESCO Finland
Mucosal proctectomy and ileoanal anastomosis
+∞
13.5
13
*
JFG73
NOMESCO Finland
Excision of ileal pelvic pouch
+∞
13.5
13
*
TNX10
NOMESCO Finland
Arthrocentesis, unspecified region, unspecified region
2.1
13.5
156
770
313
Kela drug reimbursment
Abatacept, adalimumab, anakinra, certolizumab pegol, etanercept, golimumab, infliximab, ixekizumab, sarilumab, secukinumab, tocilizumab and ustekinumab (rheumatoid diseases)
2.7
13.5
89
331
WX610
NOMESCO Finland
Patient controlled analgesia
6.5
13.4
34
53
K91.4
ICD-10 Finland
Colostomy and enterostomy malfunction
25.9
13.4
18
7
5660A
ICD-9 Finland
Abscess of anal and rectal regions[ABSCESSUS ANI ET ANORECTALIS]
18.3
13.4
20
11
OAB74
NOMESCO Finland
Nutritional guidance related to treatment and rehabilitation for medical condition
6.2
13.3
35
57
T81.8
ICD-10 Finland
Other complications of procedures, not elsewhere classified
3.9
13.3
54
141
L04AD01
ATC
ciclosporin; systemic
3.5
13.2
60
172
JN2CG
NOMESCO Finland
Extensive MRI examination of lower part of abdoment with high intensity magnet
3.9
13.1
53
138
WZA90
NOMESCO Finland
Other doctors statement
1.5
13.1
536
3868
Z93.3
ICD-10 Finland
Colostomy status
7.1
13.0
31
44
K62.5
ICD-10 Finland
Haemorrhage of anus and rectum
2.5
13.0
103
424
5609X
ICD-9 Finland
Intestinal obstruction without mention of hernia, Unspecified intestinal obstruction
28.5
13.0
17
6
WZC10
NOMESCO Finland
Extensive specialist consultion with written report
2.3
12.9
125
568
JN2DG
NOMESCO Finland
Very extensive MRI examination of lower part of abdoment with high intensity magnet
5.7
12.8
36
64
J18.9
ICD-10 Finland
Pneumonia, unspecified
1.6
12.8
398
2696
7200A
ICD-9 Finland
Ankylosing spondylitis and other inflammatory spondylopathies, Ankylosing spondylitis
11.6
12.8
23
20
5651A
ICD-9 Finland
Anal fissure and fistula, Anal fistula[FISTULA ANI]
14.1
12.7
21
15
N39.0
ICD-10 Finland
Urinary tract infection, site not specified
1.7
12.6
254
1527
J01DA09
ATC
[U] cefadroxil; inhalant, oral
1.4
12.6
618
4619
M46.1
ICD-10 Finland
Sacroiliitis, not elsewhere classified
3.8
12.6
53
143
K02.1
ICD-10 Finland
Caries of dentine
1.4
12.6
1409
12150
281
Kela drug reimbursment
Abatacept, adalimumab, anakinra, certolizumab pegol, etanercept, golimumab, infliximab, ixekizumab, sarilumab, secukinumab and tocilizumab
2.7
12.5
83
310
56399
ICD-8 Finland
Chronic enteritis and ulcerative colitis, Other
+∞
12.5
12
*
SFA30
NOMESCO Finland
Filling on tree or more surfaces of tooth
1.4
12.5
881
7041
JFB01
NOMESCO Finland
Laparoscopic partial resection of small intestine
20.1
12.4
18
9
H04.10
ICD-10 Finland
Dry eye syndrome
1.9
12.4
194
1073
NA3BG
NOMESCO Finland
Lumbar spine MRI examination with high intensity magnet
1.8
12.4
209
1188
D12.6
ICD-10 Finland
Benign neoplasm: Colon, unspecified
2.6
12.4
87
337
M54.9
ICD-10 Finland
Dorsalgia, unspecified
1.7
12.3
248
1491
SPAT1255
SPAT
Intravenous administration of medicine
2.1
12.3
138
672
B80
ICPC
Iron deficiency anaemia
3.6
12.2
55
157
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
1.8
12.2
223
1305
NF1AE
NOMESCO Finland
Hip joint ultrasound examination
3.1
12.2
67
223
JJC00
NOMESCO Finland
Allogenic transplantation of liver
15.9
12.1
19
12
R01BA52
ATC
pseudoephedrine, combinations; oral
1.4
12.0
637
4827
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
1.4
12.0
729
5664
M03BX02
ATC
tizanidine; oral
1.3
12.0
1409
12195
R06AE07
ATC
cetirizine; oral
1.4
11.9
998
8187
UJG02
NOMESCO Finland
Proctoscopy
3.4
11.9
57
171
C10AC02
ATC
colestipol; oral
13.4
11.9
20
15
JFK10
NOMESCO Finland
Freeing of adhesions in intestinal obstruction
14.7
11.8
19
13
J01EE02
ATC
sulfadiazine and trimethoprim; systemic
1.4
11.7
636
4840
S01BA01
ATC
dexamethasone; ophthalmic (corticosteroids, plain)
2.5
11.7
89
361
K90.8
ICD-10 Finland
Other intestinal malabsorption
30.2
11.6
15
5
JN1CM
NOMESCO Finland
Upper part of abdomen extensive MRI examination with 3 Tesla magnet
30.2
11.6
15
5
XF400
NOMESCO Finland
ECG with 12 standard connections
1.6
11.6
300
1934
F32.11
ICD-10 Finland
Moderate depressive episode with somatic syndrome
2.7
11.6
80
306
R01AD09
ATC
mometasone; nasal
1.4
11.6
1025
8471
B07.9
ICD-10 Finland
Verruca simplex
2.5
11.5
90
369
KH1AD
NOMESCO Finland
CT of urinary organs
2.6
11.5
80
308
R07.4
ICD-10 Finland
Chest pain, unspecified
1.5
11.5
477
3443
5560A
ICD-9 Finland
Idiopathic proctocolitis, Ulcerative (chronic) enterocolitis
+∞
11.5
11
*
K51.4
ICD-10 Finland
Inflammatory polyps
+∞
11.5
11
*
SPAT1325
SPAT
Vaccination
1.4
11.4
643
4921
N06AX11
ATC
mirtazapine; oral
1.4
11.4
660
5077
SFC01
NOMESCO Finland
Adjuvant procedure of filling therapy
1.4
11.3
585
4404
S10
ICPC
Boil/carbuncle
2.1
11.3
121
578
JGB96
NOMESCO Finland
Other proctectomy or excision of rectum
35.2
11.3
14
*
K59.0
ICD-10 Finland
Constipation
2.2
11.3
109
499
Z09.0
ICD-10 Finland
Follow-up examination after surgery for other conditions
2.0
11.2
151
795
J45.9
ICD-10 Finland
Asthma, unspecified
1.6
11.2
344
2323
JKA20
NOMESCO Finland
Cholecystectomy
3.3
11.1
55
170
56510
ICD-8 Finland
Anal fissure and fistula, Anal fistula
11.2
11.0
20
18
N20.1
ICD-10 Finland
Calculus of ureter
2.6
11.0
81
322
SPAT1254
SPAT
Administration of medicine
1.6
11.0
280
1801
L01BB01
ATC
NA
10.1
11.0
21
21
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
1.7
10.9
248
1546
0093A
ICD-9 Finland
Ill-defined intestinal infections, Diarrhoea of presumed infectious origin
4.1
10.9
41
101
K29.9
ICD-10 Finland
Gastroduodenitis, unspecified
5.3
10.9
32
61
SAA01
NOMESCO Finland
Simple examination of mouth
1.3
10.8
1709
15353
JFG20
NOMESCO Finland
Closure of enterostomy with resection of exteriorised loop
12.0
10.8
19
16
EB1AA
NOMESCO Finland
Tooth X-ray examination
1.3
10.8
1280
11018
R21
ICD-10 Finland
Rash and other nonspecific skin eruption
2.4
10.8
92
395
J01MA01
ATC
ofloxacin; systemic
1.9
10.8
154
828
J01CA04
ATC
amoxicillin; systemic
1.4
10.7
1966
18072
K63.0
ICD-10 Finland
Abscess of intestine
28.1
10.7
14
5
N06AX21
ATC
duloxetine; oral
1.7
10.7
231
1419
N06AA09
ATC
amitriptyline; systemic
1.8
10.6
179
1019
JHA20
NOMESCO Finland
Excision of lesion of anal canal or perianal tissue
4.4
10.6
37
85
R01AD12
ATC
fluticasone furoate; nasal
1.4
10.6
690
5407
L88
ICD-10 Finland
Pyoderma gangrenosum
14.2
10.5
17
12
K55.9
ICD-10 Finland
Vascular disorder of intestine, unspecified
14.2
10.5
17
12
R2130
NOMESCO Finland
Counselling and guidance which enhance independent living
1.8
10.5
165
919
N05BA04
ATC
oxazepam; oral
1.4
10.4
500
3702
M07.5
ICD-10 Finland
Arthropathy in ulcerative colitis
110.4
10.4
11
*
K60.0
ICD-10 Finland
Acute anal fissure
4.1
10.4
39
96
S01CA01
ATC
dexamethasone and antiinfectives; ophthalmic (ophth., corticosteroids and antiinfectives in comb.)
1.4
10.4
570
4329
M81.9
ICD-10 Finland
Osteoporosis, unspecified
2.8
10.4
65
235
B01AB10
ATC
tinzaparin; parenteral
2.0
10.4
132
678
Z43.2
ICD-10 Finland
Attention to ileostomy
16.1
10.3
16
10
N32.1
ICD-10 Finland
Vesicointestinal fistula
16.1
10.3
16
10
M80.4
ICD-10 Finland
Drug-induced osteoporosis with pathological fracture
12.1
10.3
18
15
6419
FHL
Other measure in this category
32.6
10.3
13
*
WX290
NOMESCO Finland
Other blockade of nerve
1.3
10.3
1109
9384
JDW98
NOMESCO Finland
Other transluminal endoscopic operation on stomach or duodenum
4.0
10.2
39
98
SPAT1083
SPAT
Initiation and monitoring of IV fluid therapy
2.3
10.1
91
404
JHB30
NOMESCO Finland
Rubber band ligature of haemorrhoids or prolapse of mucosa
2.1
10.1
113
553
ZX114
NOMESCO Finland
Intramuscular
3.6
10.1
44
124
D12.2
ICD-10 Finland
Benign neoplasm: Ascending colon
3.0
10.0
55
184
A01AB10
ATC
natamycin; local oral
2.7
10.0
67
252
N17.9
ICD-10 Finland
Acute renal failure, unspecified
2.7
10.0
68
260
UJF30
SPAT
NA
9.2
10.0
20
22
Z71.8
ICD-10 Finland
Other specified counselling
1.4
10.0
523
3936
K52.2
ICD-10 Finland
Allergic and dietetic gastroenteritis and colitis
40.2
10.0
12
*
1380
FHL
Colonoscopy, left side
40.2
10.0
12
*
Z03.3
ICD-10 Finland
Observation for suspected nervous system disorder
2.0
10.0
121
613
B82
ICPC
Anaemia other/unspecified
3.2
9.9
51
164
XQ800
NOMESCO Finland
Prick test
1.8
9.9
178
1038
J01MA06
ATC
norfloxacin; oral
1.6
9.8
245
1569
6454
FHL
Incision of perianal abscess
20.1
9.8
14
7
JJ9AE
NOMESCO Finland
Ultrasound examination of liver transplant
20.1
9.8
14
7
M03BC51
ATC
orphenadrine, combinations; systemic
1.4
9.8
597
4615
M46.9
ICD-10 Finland
Inflammatory spondylopathy, unspecified
3.8
9.8
40
107
N07BA03
ATC
varenicline; oral
2.0
9.8
128
668
K60.1
ICD-10 Finland
Chronic anal fissure
2.8
9.8
59
211
R42
ICD-10 Finland
Dizziness and giddiness
1.5
9.7
365
2574
D37.2
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Small intestine
7.4
9.7
22
30
L52
ICD-10 Finland
Erythema nodosum
5.1
9.7
29
57
SAA03
NOMESCO Finland
Extended examination of mouth
1.3
9.7
909
7524
71240
ICD-8 Finland
Rheumatoid arthritis and allied conditions, Spondylitis ankylopoietica
13.4
9.7
16
12
D07CA01
ATC
hydrocortisone and antibiotics; topical
1.6
9.6
279
1855
JA3AT
NOMESCO Finland
Cathetrisation of abdominal cavity with ultrasound guidance
3.9
9.6
38
99
L04AB06
ATC
golimumab; parenteral
4.6
9.6
32
71
K85.9
ICD-10 Finland
Acute pancreatitis, unspecified
3.3
9.6
47
146
T81.3
ICD-10 Finland
Disruption of operation wound, not elsewhere classified
2.9
9.5
55
190
JGB30
NOMESCO Finland
Abdominoperineal excision of rectum
10.1
9.5
18
18
L73.2
ICD-10 Finland
Hidradenitis suppurativa
3.9
9.5
37
95
A02BX02
ATC
sucralfate; oral
2.5
9.5
71
285
JAD10
NOMESCO Finland
Repair of incisional hernia
5.7
9.5
26
46
SFA20
NOMESCO Finland
Filling on two surfaces of tooth
1.3
9.5
1354
11872
6525
FHL
Enterostomy occlusion
100.4
9.4
10
*
JFH11
NOMESCO Finland
Laparoscopic colectomy
100.4
9.4
10
*
K60.2
ICD-10 Finland
Anal fissure, unspecified
3.1
9.4
49
159
6408
FHL
Colectomy and ileostomy
+∞
9.4
9
*
A02BA04
ATC
nizatidine; systemic
1.9
9.4
131
701
M03BC01
ATC
orphenadrine (citrate); systemic
1.4
9.4
522
3970
J01MA14
ATC
moxifloxacin; systemic
1.8
9.4
168
977
JFB50
NOMESCO Finland
Other resection of colon
12.4
9.3
16
13
M01AE03
ATC
ketoprofen; systemic, rectal
1.3
9.3
727
5842
N05CF02
ATC
zolpidem; oral
1.5
9.3
355
2507
JFB46
NOMESCO Finland
Resection of sigmoid colon
4.7
9.3
30
64
D13.3
ICD-10 Finland
Benign neoplasm: Other and unspecified parts of small intestine
10.7
9.3
17
16
E000002
ATC
NA
1.6
9.3
250
1633
E27.3
ICD-10 Finland
Drug-induced adrenocortical insufficiency
9.5
9.3
18
19
K08.1
ICD-10 Finland
Loss of teeth due to accident, extraction or local periodontal disease
1.7
9.2
177
1051
K59.09
ICD-10 Finland
Constipation, unspecified
2.1
9.2
104
513
JN2AE
NOMESCO Finland
Ultrasound examination of lower part of abdomen without contrast
4.2
9.2
33
79
D05AX52
ATC
calcipotriol, combinations; topical
2.0
9.2
113
577
M79.0
ICD-10 Finland
Rheumatism, unspecified
2.5
9.1
72
298
JWA00
NOMESCO Finland
Repair of wound dehiscence in gastroenterological surgery
7.7
9.1
20
26
SGC00
NOMESCO Finland
Local medication of root channels of tooth
1.6
9.1
248
1620
N06AX16
ATC
venlafaxine; oral
1.5
9.1
308
2123
Z98.8
ICD-10 Finland
Other specified postsurgical states
4.2
9.1
33
80
J01EA01
ATC
trimethoprim; systemic
1.4
9.0
459
3431
N03AX12
ATC
gabapentin; oral
1.5
9.0
288
1956
NA2AA
NOMESCO Finland
Thoracal spine X-ray examination without contrast
2.9
9.0
53
187
I84.2
ICD-10 Finland
Internal hemorrhoids without complication
1.9
8.9
137
759
S29
ICPC
Skin symptom/complaint other
1.5
8.9
321
2243
H22.1*M45
ICD-10 Finland
Iridocyclitis in ankylosing spondylitis
12.6
8.9
15
12
H20.1
ICD-10 Finland
Chronic iridocyclitis
4.1
8.8
33
82
Y0599
ICD-8 Finland
Investigation of digestive system
3.7
8.8
36
97
K80.3
ICD-10 Finland
Calculus of bile duct with cholangitis
5.9
8.7
23
39
R53
ICD-10 Finland
Malaise and fatigue
1.4
8.7
393
2870
K80.0
ICD-10 Finland
Calculus of gallbladder with acute cholecystitis
2.3
8.7
78
344
M79.7
ICD-10 Finland
Fibromyalgia
2.3
8.7
78
346
D06
ICPC
Abdominal pain localized other
1.7
8.7
174
1048
N18.9
ICD-10 Finland
Chronic kidney disease, unspecified
2.2
8.7
83
379
D07CC01
ATC
betamethasone and antibiotics; topical
1.5
8.6
261
1752
H15.1
ICD-10 Finland
Episcleritis
3.4
8.6
40
120
KH1AE
NOMESCO Finland
Urinary tract ultrasound examination
2.0
8.6
104
527
G44.2
ICD-10 Finland
Tension-type headache
1.5
8.6
276
1878
QBE15
NOMESCO Finland
Excision of other superficial lesion of skin of trunk
8.2
8.6
18
22
KBV02
NOMESCO Finland
Cystoscopic insertion of stent into ureter
3.0
8.6
47
159
QBA10
NOMESCO Finland
Incision of skin of trunk
4.0
8.5
32
80
A03
ICPC
Fever
1.4
8.5
374
2721
N20.9
ICD-10 Finland
Urinary calculus, unspecified
2.6
8.4
58
224
XF600
NOMESCO Finland
Bloodpressure measurement
1.9
8.4
121
652
Z01.4
ICD-10 Finland
Gynaecological examination (general)(routine)
1.5
8.4
341
2439
Z76.9
ICD-10 Finland
Person encountering health services in unspecified circumstances
1.8
8.4
151
881
WX105
NOMESCO Finland
Surface analgesia on skin or mucosa
1.6
8.4
202
1282
R05DA20
ATC
opium alkaloids and derivatives - combinations
1.4
8.4
531
4120
K62.4
ICD-10 Finland
Stenosis of anus and rectum
12.8
8.4
14
11
K29.6
ICD-10 Finland
Other gastritis
4.5
8.3
28
63
R35
ICD-10 Finland
Polyuria
1.9
8.3
115
614
JFH33
NOMESCO Finland
Total colectomy, mucosal proctectomy, ileoanal anastomosis and ileostomy
+∞
8.3
8
*
K73.2
ICD-10 Finland
Chronic active hepatitis, not elsewhere classified
8.5
8.3
17
20
K63.9
ICD-10 Finland
Disease of intestine, unspecified
8.5
8.3
17
20
SCA01
NOMESCO Finland
Simple analysis and advice of nutrition with regard to dentistry
1.3
8.3
668
5378
T91
ICPC
Vitamin/nutritional deficiency
5.8
8.3
22
38
JN4AD
NOMESCO Finland
Body CT examination
1.9
8.3
124
682
L73.8
ICD-10 Finland
Other specified follicular disorders
3.6
8.2
35
98
S01GX01
ATC
cromoglicic acid; ophthalmic
1.4
8.2
438
3297
D12.5
ICD-10 Finland
Benign neoplasm: Sigmoid colon
2.4
8.2
67
285
L82
ICD-10 Finland
Seborrhoeic keratosis
1.5
8.2
256
1733
SPAT1148
SPAT
Treatment of chronic ulcer or burn
1.6
8.1
215
1395
TQW80
NOMESCO Finland
Local dermatologic skincare
2.6
8.1
57
224
K45.8
ICD-10 Finland
Other specified abdominal hernia without obstruction or gangrene
5.7
8.1
22
39
T81.9
ICD-10 Finland
Unspecified complication of procedure
3.0
8.1
43
143
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
1.6
8.0
193
1224
J01FA09
ATC
clarithromycin; systemic
1.3
8.0
673
5450
Z35.8
ICD-10 Finland
Supervision of other high-risk pregnancies
1.6
7.9
182
1141
K90.0
ICD-10 Finland
Coeliac disease
2.4
7.9
63
266
L88
ICPC
Rheumatoid/seropositive arthritis
2.2
7.9
78
362
M05BB03
ATC
alendronic acid and colecalciferol; oral
3.4
7.9
36
107
TK800
NOMESCO Finland
Hemodialysis
2.8
7.9
47
168
R05FA02
ATC
opium derivatives and expectorants; systemic
1.3
7.9
814
6776
M01AX17
ATC
nimesulide; oral
1.4
7.9
405
3031
NH3DA
NOMESCO Finland
Bilateral foot X-ray examination
2.7
7.9
51
192
JHD00
NOMESCO Finland
Anal dilatation
5.4
7.8
22
41
XX6XT
NOMESCO Finland
Other intravascular therapy with radiological guidance
8.5
7.8
16
19
M01AH02
ATC
rofecoxib; oral
1.6
7.8
213
1398
E000007
ATC
NA
1.8
7.7
120
669
I84.9
ICD-10 Finland
Unspecified hemorrhoids without complication
2.0
7.7
93
470
JFB40
NOMESCO Finland
Resection of transverse colon
15.1
7.7
12
8
1470
FHL
Rectoscopy
5.3
7.7
22
42
JKA21
NOMESCO Finland
Laparoscopic cholecystectomy
1.6
7.6
203
1321
L20.9
ICD-10 Finland
Atopic dermatitis, unspecified
2.0
7.6
86
427
JN3DG
NOMESCO Finland
Very extensive MRI examination with high intensity magnet
4.9
7.6
23
47
A02BA03
ATC
famotidine; systemic
2.3
7.5
65
284
I84.5
ICD-10 Finland
External hemorrhoids without complication
2.4
7.5
60
254
NA6AA
NOMESCO Finland
Sacro-iliac joint X-ray examination
5.4
7.5
21
39
SHA01
NOMESCO Finland
Correction of physiology of bite - simple therapy visit
1.5
7.5
235
1589
E78.0
ICD-10 Finland
Pure hypercholesterolaemia
0.6
7.5
137
2137
K76.9
ICD-10 Finland
Liver disease, unspecified
3.4
7.5
34
101
D29
ICPC
Digestive symptom/complaint other
2.9
7.5
44
156
D07BC01
ATC
betamethasone and antiseptics; topical
1.5
7.5
224
1500
XLD00
NOMESCO Finland
Sytologyspecimen from mouth of uterus
1.5
7.4
230
1552
Z87.1
ICD-10 Finland
Personal history of diseases of the digestive system
1.3
7.4
902
7657
K85.3
ICD-10 Finland
Drug-induced acute pancreatitis
80.3
7.4
8
*
LC2BE
NOMESCO Finland
Transvaginal ultrasound examination of uterus, parametria and lower abdomen
1.3
7.4
544
4309
XG412
NOMESCO Finland
Flow-volume spirometry with bronchospasmolysis
1.9
7.4
111
611
K59.9
ICD-10 Finland
Functional intestinal disorder, unspecified
3.4
7.4
33
97
M50.8
ICD-10 Finland
Other cervical disc disorders
6.0
7.4
19
32
Z01.0
ICD-10 Finland
Examination of eyes and vision
1.4
7.4
310
2232
ZX100
NOMESCO Finland
Oral
3.3
7.4
35
108
TPH90
NOMESCO Finland
Removal of fixed intravenous catheter
3.1
7.4
37
119
R60.0
ICD-10 Finland
Localized oedema
1.6
7.3
174
1101
JFA76
NOMESCO Finland
Closure of fistula of small intestine
+∞
7.3
7
*
6410
FHL
Panprococolectomy and ileostomy
+∞
7.3
7
*
4AB04
NOMESCO Finland
NA
+∞
7.3
7
*
R4110
NOMESCO Finland
Physiotherapy
1.3
7.3
507
3982
D07AB08
ATC
desonide; topical
1.5
7.3
212
1413
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
1.5
7.3
262
1826
T81.0
ICD-10 Finland
Haemorrhage and haematoma complicating a procedure, not elsewhere classified
1.8
7.3
114
639
K13.78
ICD-10 Finland
Other change in the oral mucosa
2.8
7.2
43
154
127
Kela drug reimbursment
Transplant complication
2.8
7.2
43
154
R03BA05
ATC
fluticasone; inhalant
1.4
7.2
365
2718
JHA10
NOMESCO Finland
Biopsy of anal canal
15.8
7.2
11
7
ZX110
NOMESCO Finland
Intracutaneous
15.8
7.2
11
7
JHD10
NOMESCO Finland
Myotomy of anal sphincter
5.4
7.2
20
37
D82
ICPC
Teeth/gum disease
1.3
7.2
793
6648
TPH05
NOMESCO Finland
Open cannulation of peripheral vein
4.8
7.1
22
46
Z02.7
ICD-10 Finland
Issue of medical certificate
1.8
7.1
120
687
318
Kela drug reimbursment
Teriparatide
7.9
7.1
15
19
R07.0
ICD-10 Finland
Pain in throat
1.7
7.1
139
835
-50
ICPC
Medication/prescr/renewal
2.0
7.1
86
438
JWF00
NOMESCO Finland
Reoperation for insufficiency of anastomosis or suture in gastroenterological surgery
12.0
7.1
12
10
SBB00
NOMESCO Finland
Fotograf of mouth and teeth
2.0
7.1
88
452
K85.8
ICD-10 Finland
Other acute pancreatitis
5.3
7.1
20
38
JN3DE
NOMESCO Finland
Abdominal extensive ultrasoudn examination with blood flow measurements after transplantation
5.6
7.1
19
34
WX000
NOMESCO Finland
Monitoring vital functions without anesthesy
2.1
7.1
77
376
H05AA02
ATC
teriparatide; parenteral
8.8
7.0
14
16
R31
ICD-10 Finland
Unspecified haematuria
1.7
7.0
140
844
ND2DA
NOMESCO Finland
Bilateral hand X-ray examination
2.7
7.0
46
175
K08.80
ICD-10 Finland
Toothache NOS
1.6
7.0
174
1113
A04.9
ICD-10 Finland
Bacterial intestinal infection, unspecified
4.7
7.0
22
47
N05CD07
ATC
temazepam; oral
1.6
7.0
177
1138
R03BA08
ATC
ciclesonide; inhalant
1.7
7.0
153
946
R01AD58
ATC
fluticasone, combinations; inhalant, nasal
1.3
7.0
466
3634
L57.0
ICD-10 Finland
Actinic keratosis
1.8
7.0
119
686
SDA02
NOMESCO Finland
Parodonthologic therapy
1.3
7.0
695
5744
TDM10
NOMESCO Finland
Puncture of maxillary antrum
2.0
7.0
85
433
SPAT1312
SPAT
General health counselling
1.3
7.0
680
5602
XKD00
NOMESCO Finland
Uroflowmetry
1.5
6.9
227
1552
J01EE01
ATC
sulfamethoxazole and trimethoprim; systemic
1.8
6.9
114
647
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
1.5
6.9
238
1646
A41.9
ICD-10 Finland
Sepsis, unspecified
2.3
6.9
59
260
K75.4
ICD-10 Finland
Autoimmune hepatitis
13.8
6.9
11
8
K60.4
ICD-10 Finland
Rectal fistula
13.8
6.9
11
8
CJE20
NOMESCO Finland
Phakoemulsification with implantation of artificial lens in posterior chamber
1.4
6.9
321
2359
SGA01
NOMESCO Finland
Tooth opening as first aid
1.4
6.9
356
2663
K57.1
ICD-10 Finland
Diverticular disease of small intestine without perforation or abscess
3.6
6.9
29
82
FB1BD
NOMESCO Finland
Extensive CT examination of arteria pulmonalis
1.7
6.8
126
740
A01AB04
ATC
amphotericin B; local oral
2.1
6.8
76
376
D28
ICPC
Limited function/disability (D)
8.3
6.8
14
17
S03
ICPC
Warts
2.7
6.8
44
165
TEW99
NOMESCO Finland
Other minor procedure in surgery of teeth, jaws, mouth and pharynx
1.9
6.8
100
546
JN4BD
NOMESCO Finland
Extensive body CT
1.6
6.8
167
1067
E87.6
ICD-10 Finland
Hypokalaemia
2.5
6.8
51
208
M05BA07
ATC
risedronic acid; oral
2.6
6.8
45
173
N11.8
ICD-10 Finland
Other chronic tubulo-interstitial nephritis
11.0
6.8
12
11
F33.11
ICD-10 Finland
Recurrent depression, moderate episode of somatic syndrome
2.4
6.8
54
227
QBA25
NOMESCO Finland
Destruction of lesion of skin of trunk
3.5
6.8
29
83
A04AA01
ATC
ondansetron; systemic, rectal
1.8
6.8
117
677
M79.1
ICD-10 Finland
Myalgia
1.5
6.8
256
1803
SPAT1144
SPAT
Treatment of reopened or infected surgical wound
1.7
6.8
122
714
KAT00
NOMESCO Finland
Extracorporeal shock wave lithotripsy of pelvis of kidney
4.5
6.8
22
49
D51.9
ICD-10 Finland
Vitamin B12deficiency anaemia, unspecified
3.9
6.8
26
68
56096
ICD-8 Finland
Intestinal obstruction without mention of hernia, Ileus propter adhaesionem (functione laesa circulationis intestinalis non indicata)
40.1
6.8
8
*
JKD20
NOMESCO Finland
Anastomosis of bile duct to jejunum
40.1
6.8
8
*
JJ5AT
NOMESCO Finland
NA
16.7
6.7
10
6
K83.8
ICD-10 Finland
Other specified diseases of biliary tract
16.7
6.7
10
6
D50
ICD-10 Finland
Iron deficiency anaemia
2.6
6.7
47
184
N83.2
ICD-10 Finland
Other and unspecified ovarian cysts
1.6
6.7
189
1247
TQW99
NOMESCO Finland
Other minor procedure on skin
2.0
6.7
81
413
CBB30
NOMESCO Finland
Excision of lesion of eyelid
2.4
6.7
51
212
A03BA03
ATC
hyoscyamine; oral
4.9
6.7
20
41
R05
ICD-10 Finland
Cough
1.4
6.6
358
2696
R15
ICD-10 Finland
Faecal incontinence
2.7
6.6
41
152
R2110
NOMESCO Finland
Giving the first information
1.6
6.6
146
905
H57.1
ICD-10 Finland
Ocular pain
2.1
6.6
70
340
H01
ICPC
Ear pain/earache
1.5
6.6
224
1545
J15.9
ICD-10 Finland
Bacterial pneumonia, unspecified
1.7
6.5
132
801
L02.9
ICD-10 Finland
Cutaneous abscess, furuncle and carbuncle, unspecified
2.2
6.5
61
279
SPAT1249
SPAT
Treatment-related counselling outside office
1.3
6.5
824
7003
N20.0
ICD-10 Finland
Calculus of kidney
2.7
6.5
42
158
SPAT1104
SPAT
Monitoring of emergency patient
1.7
6.5
118
695
K13.79
ICD-10 Finland
Change in the oral mucosa UNS
2.4
6.5
52
220
A41.1
ICD-10 Finland
Sepsis due to other specified staphylococcus
6.2
6.5
16
26
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
1.5
6.5
198
1333
5BA08
NOMESCO Finland
NA
5.3
6.5
18
34
EP1AE
NOMESCO Finland
Neck ultrasound examination
1.8
6.4
105
597
NG1AA
NOMESCO Finland
Knee X-ray examination without contrast
1.5
6.4
186
1234
D18
ICPC
Change in faeces/bowel movements
2.8
6.4
39
143
K35.9
ICD-10 Finland
Acute appendicitis, unspecified
1.6
6.4
168
1092
JFC10
NOMESCO Finland
Ileotransversostomy
70.0
6.4
7
*
ND2AA
NOMESCO Finland
Hand and fingers X-ray examination
1.6
6.4
163
1049
A02BC04
ATC
rabeprazole; oral
1.6
6.4
160
1027
K61.2
ICD-10 Finland
Anorectal abscess
7.4
6.4
14
19
R20.2
ICD-10 Finland
Paraesthesia of skin
1.7
6.4
131
799
D12.8
ICD-10 Finland
Benign neoplasm: Rectum
2.2
6.4
63
296
K25.7
ICD-10 Finland
Gastric ulcer, Chronic without haemorrhage or perforation
4.7
6.4
20
43
N80.3
ICD-10 Finland
Endometriosis of pelvic peritoneum
2.1
6.4
65
308
SGB10
NOMESCO Finland
Fiiling of rooth of tooth with one root channel
1.5
6.4
236
1655
NK6PA
NOMESCO Finland
Measurement of bone density from one location with X-ray
14.3
6.4
10
7
L01
ICPC
Neck symptom/complaint
1.4
6.4
262
1877
G03DC03
ATC
lynestrenol; oral
2.5
6.4
47
193
SGA02
NOMESCO Finland
Opening and dilatation of root canal of tooth
1.4
6.4
255
1817
QAA25
NOMESCO Finland
Destruction of lesion of head or neck
2.9
6.4
37
131
C07AB07
ATC
bisoprolol; oral
1.3
6.4
731
6141
M51.1
ICD-10 Finland
Lumbar and other intervertebral disc disorders with radiculopathy
1.4
6.3
267
1922
L30.3
ICD-10 Finland
Infective dermatitis
2.1
6.3
63
298
N17.8
ICD-10 Finland
Other acute renal failure
4.4
6.3
21
48
KH1AA
NOMESCO Finland
Urinary tract X-ray examination without contrast
3.4
6.3
28
83
WX004
NOMESCO Finland
Patient-controlled sedation
5.2
6.3
18
35
JA3BT
NOMESCO Finland
Cathetrisation of abdominal cavity with X-ray guidance
9.3
6.3
12
13
JFH00
NOMESCO Finland
Total colectomy and ileorectal anastomosis
9.3
6.3
12
13
ULA02
NOMESCO Finland
Kolposcopy
1.5
6.3
193
1303
JFC20
NOMESCO Finland
Other enterocolostomy
18.1
6.3
9
5
56909
ICD-8 Finland
Other diseases of intestines and peritoneum, Unspecified
+∞
6.3
6
*
5761C
ICD-9 Finland
Other disorders of biliary tract, Cholangitis[CHOLANGITIS SCLEROSIVA]
+∞
6.3
6
*
K52.0
ICD-10 Finland
Gastroenteritis and colitis due to radiation
+∞
6.3
6
*
NH3EA
NOMESCO Finland
Feet X-ray examination with load
2.6
6.2
42
164
M81.8
ICD-10 Finland
Other osteoporosis
4.8
6.2
19
40
R60.9
ICD-10 Finland
Oedema, unspecified
2.0
6.2
75
382
D06AX01
ATC
fusidic acid; topical (antibiotics for topical use)
1.5
6.2
192
1296
JHB00
NOMESCO Finland
Hemorrhoidectomy
2.1
6.2
62
295
K75.9
ICD-10 Finland
Inflammatory liver disease, unspecified
3.3
6.1
28
85
GD1DD
NOMESCO Finland
High resolution CT examination of lungs
1.9
6.1
83
443
KC1EE
NOMESCO Finland
Ultrasound measurement of residual urine
1.5
6.1
187
1261
C17.9
ICD-10 Finland
Malignant neoplasm: Small intestine, unspecified
7.7
6.1
13
17
M02AA10
ATC
ketoprofen; topical
1.4
6.1
268
1944
SHB00
NOMESCO Finland
Prepation and fitting of bite rail to mouth
1.5
6.1
220
1538
F33.2
ICD-10 Finland
Recurrent depressive disorder, current episode severe without psychotic symptoms
1.8
6.1
100
570
SPAT1125
SPAT
Stoma care and guidance
3.6
6.1
25
70
K03.66
ICD-10 Finland
Tooth plaque
1.7
6.1
129
792
M01AE02
ATC
naproxen; oral, rectal
1.2
6.1
1249
11188
L02.2
ICD-10 Finland
Cutaneous abscess, furuncle and carbuncle of trunk
1.9
6.0
80
422
M13.9
ICD-10 Finland
Arthritis, unspecified
1.6
6.0
134
836
6101
FHL
Exploratory laparotomy, includes possible biopases
6.7
6.0
14
21
S85
ICPC
Pilonidal cyst/fistula
10.0
6.0
11
11
Mortality – FinRegistry
↥Association
Association between endpoint CHRONSMALL and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| CHRONSMALL | 1.57 [1.37, 1.79] | < 0.001 |
| Birth year | 0.993 [0.98, 1.0] | 0.104 |
During the follow-up period (1.1.1998 — 31.12.2019), 611 out of 6408 females with CHRONSMALL died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| CHRONSMALL | 1.399 [1.24, 1.58] | < 0.001 |
| Birth year | 0.986 [0.98, 1.0] | 0.003 |
During the follow-up period (1.1.1998 — 31.12.2019), 700 out of 5914 males with CHRONSMALL died.
Mortality risk
Mortality risk for people of age
years, who have CHRONSMALL.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.143% | 0.206% |
| 5 | 0.879% | 1.518% |
| 10 | 2.039% | 3.892% |
| 15 | 4.114% | 6.981% |
| 20 | 7.229% | 12.134% |
Relationships between endpoints
↥Index endpoint: CHRONSMALL – Crohn's disease of small intestine
GWS hits: 11
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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