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This is a non-core endpoint: only basic statistics are computed.

See its core counterpart C3_MESOTHELIOMA_EXALLC for full statistics.

Mesothelioma

C3_MESOTHELIOMA

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 C45
  • Hospital discharge: ICD-9 158|163
  • Hospital discharge: ICD-8 158|163
  • Cause of death: ICD-10 C45
  • Cause of death: ICD-9 158|163
  • Cause of death: ICD-8 158|163
  • Cancer registry: Topography ICD-O-3 ANY
  • Cancer registry: Morphology ICD-O-3 905[0-3]
  • Cancer registry: Behaviour codes 3

3 out of 7 registries used, show all original rules.

451

4. Check minimum number of events

None

451

5. Include endpoints

None

451

6. Filter based on genotype QC (FinnGen only)

451

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF8
Parent code in ICD-10
C45-C49
Name in latin
Mesothelioma

Similar endpoints

List of similar endpoints to Mesothelioma based on the number of shared cases.

Venn diagram with an highlighted set fully inside another set Similar with more cases:

Venn diagram with a set fully inside an highlighted set Similar with less cases:

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

All Female Male
Number of individuals 451 117 334
Unadjusted period prevalence (%) 0.12 0.04 0.15
Median age at first event (years) 70.24 64.97 72.09

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
404
Matched controls
4041
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
C45.0
ICD-10 Finland
Mesothelioma of pleura
+∞
323.0
299
*
J90
ICD-10 Finland
Pleural effusion, not elsewhere classified
41.8
167.7
216
108
9050/3-C38.4
ICD-O-3
Mesothelioma, malignant of pleura, NOS
+∞
135.2
122
*
130
Kela drug reimbursment
Malignant tumour
15.5
111.3
210
264
GAC01
NOMESCO Finland
Endoscopic biopsy of pleura
1303.1
106.3
99
*
9052/3-C38.4
ICD-O-3
Epithelioid mesothelioma, malignant of pleura, NOS
+∞
103.7
95
*
H02AB02
ATC
dexamethasone; systemic
14.5
95.1
179
210
J94.8
ICD-10 Finland
Other specified pleural conditions
47.3
78.2
95
26
A03FA01
ATC
metoclopramide; systemic, rectal
7.2
65.8
202
492
N02AA05
ATC
oxycodone; systemic
7.2
64.4
195
463
GAA10
NOMESCO Finland
Intercostal insertion of pleural drainage tube
25.0
62.3
89
45
C45.9
ICD-10 Finland
Mesothelioma, unspecified
+∞
59.9
56
*
GA4YT
NOMESCO Finland
Puncture of pleura with ultrasound guidance
15.5
58.2
100
84
C45.1
ICD-10 Finland
Mesothelioma of peritoneum
+∞
57.7
54
*
Z51.5
ICD-10 Finland
Palliative care
9.8
55.4
122
170
A04AA01
ATC
ondansetron; systemic, rectal
11.9
52.5
102
111
TGA30
NOMESCO Finland
Thoracocentesis
49.1
49.1
59
14
GAC00
NOMESCO Finland
Biopsy of pleura
86.5
48.3
53
7
GA1AE
NOMESCO Finland
Ultrasound examination of thorax
17.3
41.1
66
45
1BA04
NOMESCO Finland
NA
439.0
40.9
40
*
J94.9
ICD-10 Finland
Pleural condition, unspecified
98.5
33.3
36
*
GD5BD
NOMESCO Finland
Thorax and upper abdomen combined extensive CT examination of
13.4
33.1
59
51
9051/3-C38.4
ICD-O-3
Fibrous mesothelioma, malignant of pleura, NOS
+∞
32.7
31
*
GD1BD
NOMESCO Finland
Thorax extensive CT-examination
6.9
30.0
80
140
JN4BD
NOMESCO Finland
Extensive body CT
4.9
29.9
111
290
WD125
NOMESCO Finland
Demanding cystostatic therapy of methastized malignancy
8.0
29.1
69
101
L01CA04
ATC
vinorelbine; systemic
33.8
28.7
37
12
R91
ICD-10 Finland
Abnormal findings on diagnostic imaging of lung
4.7
28.5
111
303
GAA96
NOMESCO Finland
Other open or percutaneous drainage of pleural cavity
39.7
26.6
33
9
WX302
NOMESCO Finland
Thoracal epidural anesthesy
7.5
26.5
65
100
D38.2
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Pleura
72.0
24.1
27
*
C38.4
ICD-10 Finland
Malignant neoplasm: Pleura
254.3
23.9
24
*
GA4AT
NOMESCO Finland
Cathetrisation of pleural cavity with ultrasound guidance
17.6
21.8
34
21
UGC12
NOMESCO Finland
Flexible bronchoscopy
4.4
21.5
85
230
GD1AT
NOMESCO Finland
Biopsy of the lung with ultrasound guidance
220.8
20.8
21
*
GD1AA
NOMESCO Finland
Thorax X-ray examination
2.7
20.6
241
1419
A04AA55
ATC
palonosetron, combinations; systemic
18.3
19.0
29
17
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
3.2
18.9
120
473
R84
ICPC
Malignant neoplasm bronchus/lung
40.5
18.7
23
6
9053/3-C38.4
ICD-O-3
Mesothelioma, biphasic, malignant of pleura, NOS
+∞
17.8
17
*
WD105
NOMESCO Finland
Cystostatic therapy of methastized malignancy
6.1
17.3
48
87
WX600
NOMESCO Finland
Single shot through catheter
16.9
17.3
27
17
J92.0
ICD-10 Finland
Pleural plaque with presence of asbestos
6.3
16.6
45
79
WF004
NOMESCO Finland
Palliative radiotherapy
9.4
16.0
33
38
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
3.6
15.6
77
250
A06AH03
ATC
naloxegol; oral
13.8
15.4
26
20
GD1AD
NOMESCO Finland
Thorax CT examination
5.6
15.2
45
88
B03BA03
ATC
hydroxocobalamin; parenteral
4.0
15.1
64
182
GDD20
NOMESCO Finland
Extended pneumonectomy
+∞
14.7
14
*
GAC43
NOMESCO Finland
Total decortication of pleura
+∞
14.7
14
*
QBC00
NOMESCO Finland
Removal of foreign body from skin of trunk or subcutaneous tissue
+∞
14.7
14
*
GAA31
NOMESCO Finland
Thoracoscopy
37.5
14.6
18
5
J01MA12
ATC
levofloxacin; systemic
2.7
14.5
119
543
A04AA02
ATC
granisetron; systemic, transdermal
4.6
13.7
48
114
GDA11
NOMESCO Finland
Thoracoscopic biopsy of lung
77.8
13.7
15
*
C45
ICD-10 Finland
Mesothelioma
+∞
13.6
13
*
J01MA14
ATC
moxifloxacin; systemic
3.4
13.2
67
221
GD5AD
NOMESCO Finland
Thorax and upper abdomen combined CT examination of
11.5
13.2
24
22
GD1BA
NOMESCO Finland
Extensive X-ray examination of thorax
10.6
12.7
24
24
R82
ICPC
Pleurisy/pleural effusion
+∞
12.6
12
*
C45.7
ICD-10 Finland
Mesothelioma of other sites
+∞
12.6
12
*
ZX120
NOMESCO Finland
Intravenous
3.4
12.5
64
213
N02AA01
ATC
morphine; systemic, rectal
9.1
12.2
25
29
WF049
NOMESCO Finland
Radiotherapy of metastasis
5.1
11.8
37
78
WX602
NOMESCO Finland
Repeated or continuing anesthesia shots throug a catheter
4.1
11.7
47
127
GAC30
NOMESCO Finland
Artificial pneumothorax
+∞
11.5
11
*
GDD96
NOMESCO Finland
Other pneumonectomy
+∞
11.5
11
*
N02AB03
ATC
fentanyl; nasal, sublingual, transdermal
4.1
11.4
45
120
JN4AD
NOMESCO Finland
Body CT examination
3.4
11.4
57
186
WZC30
NOMESCO Finland
Teaching
2.9
11.3
75
298
JAL30
NOMESCO Finland
Omentectomy
28.9
10.8
14
5
FB1BD
NOMESCO Finland
Extensive CT examination of arteria pulmonalis
3.6
10.5
49
151
JAL20
NOMESCO Finland
Excision or destruction of lesion of peritoneum
112.8
10.5
11
*
Z57.2
ICD-10 Finland
Occupational exposure to dust
33.5
10.4
13
*
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
3.6
10.1
46
140
GAC97
NOMESCO Finland
Other endoscopic operation on pleura
30.8
9.4
12
*
TK800
NOMESCO Finland
Hemodialysis
5.4
9.3
27
53
J18.9
ICD-10 Finland
Pneumonia, unspecified
2.0
9.2
149
906
TPH04
NOMESCO Finland
Cathetrisation of vein
2.2
9.1
102
532
WD115
NOMESCO Finland
Multiple cystostatic therapy of methastized malignancy
6.0
8.7
23
40
GD1CT
NOMESCO Finland
Biopsy of the lung with CT guidance
8.1
8.4
18
23
GAC37
NOMESCO Finland
Endoscopic chemical pleurodesis
91.9
8.4
9
*
J18.0
ICD-10 Finland
Bronchopneumonia, unspecified
6.5
8.4
21
34
YG1BD
NOMESCO Finland
Extensive CT examination of thorax for dose design of radiotherapy
6.1
8.4
22
38
1638X
ICD-9 Finland
Malignant neoplasm of pleura, Other specified sites of pleura
+∞
8.4
8
*
9052/3-C48.2
ICD-O-3
Epithelioid mesothelioma, malignant of peritoneum, NOS
+∞
8.4
8
*
Z2446
NOMESCO Finland
Social worker
3.5
8.3
38
116
R06.0
ICD-10 Finland
Dyspnoea
2.0
8.2
121
704
C78.2
ICD-10 Finland
Secondary malignant neoplasm of pleura
17.6
8.1
12
7
R85
ICPC
Malignant neopl respiratory other
22.5
8.1
11
5
N03AX16
ATC
pregabalin; oral
2.1
7.7
99
543
GAB10
NOMESCO Finland
Antero- or postero-lateral thoracotomy
18.8
7.6
11
6
GD2FN
NOMESCO Finland
Lung ventilation distribution isotope examination (radiospirometry)
81.5
7.4
8
*
SPAT1062
SPAT
Lung clearance therapy
81.5
7.4
8
*
9050/3-C48.2
ICD-O-3
Mesothelioma, malignant of peritoneum, NOS
+∞
7.3
7
*
1580A
ICD-9 Finland
Malignant neoplasm of retroperitoneum and peritoneum, Retroperitoneum
+∞
7.3
7
*
GA2CT
NOMESCO Finland
Pleural biopsy with CT guidance
+∞
7.3
7
*
H02AB06
ATC
prednisolone; systemic
1.8
7.3
193
1369
A79
ICPC
Malignancy NOS
8.1
7.2
15
19
GA3AT
NOMESCO Finland
Pleural cytology with ultrasound guidance
20.4
7.2
10
5
J86.9
ICD-10 Finland
Pyothorax without fistula
7.2
7.1
16
23
A04AD12
ATC
aprepitant; systemic
6.5
7.0
17
27
YG1AD
NOMESCO Finland
CT examination of thorax for dose design of radiotherapy
7.7
7.0
15
20
WX408
NOMESCO Finland
General anesthesy, balanced
1.9
6.9
113
681
XX1XW
NOMESCO Finland
Extensive written report from radiologist
6.3
6.8
17
28
GA2AT
NOMESCO Finland
Pleural biopsy with ultrasound guidance
40.7
6.8
8
*
1990X
ICD-9 Finland
Malignant neoplasm without specification of site, Disseminated
70.9
6.4
7
*
6101
FHL
Exploratory laparotomy, includes possible biopases
14.6
6.4
10
7
A04AA03
ATC
tropisetron; systemic
18.4
6.3
9
5
CJE20
NOMESCO Finland
Phakoemulsification with implantation of artificial lens in posterior chamber
0.5
6.3
72
1179
GAC20
NOMESCO Finland
Excision or destruction of lesion of pleura
+∞
6.3
6
*
5119X
ICD-9 Finland
Pleurisy, Unspecified pleural effusion
12.8
6.1
10
8
R4110
NOMESCO Finland
Physiotherapy
1.9
6.1
108
662

Mortality – FinRegistry

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

Index endpoint: C3_MESOTHELIOMA – Mesothelioma

GWS hits: -

This endpoint is excluded from FinRegistry analyses (omitted endpoint).