Streptococcus and staphylococcus as the cause of diseases classified to other chapters

AB1_STREPTSTAPHYCOCC_INOTHER

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 B95
  • Cause of death: ICD-10 B95

2 out of 7 registries used, show all original rules.

206

4. Check minimum number of events

None

206

5. Include endpoints

None

206

6. Filter based on genotype QC (FinnGen only)

206

Control definitions (FinnGen only)

Control exclude
AB1_BACT_BIR_OTHER_INF_AGENTS

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF5

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 2560 1085 1457
Only index persons 1924 822 1102
Unadjusted period prevalence (%)
Whole population 0.04 0.03 0.04
Only index persons 0.04 0.03 0.04
Median age at first event (years)
Whole population 38.73 37.89 39.06
Only index persons 40.34 40.80 39.99

-FinnGen-

Key figures

All Female Male
Number of individuals 206 81 125
Unadjusted period prevalence (%) 0.04 0.03 0.06
Median age at first event (years) 55.33 54.10 56.13

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
195
Matched controls
1952
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
B95.6
ICD-10 Finland
Staphylococcus aureus as the cause of diseases classified to other chapters
+∞
81.0
72
*
B95.0
ICD-10 Finland
Streptococcus, group A, as the cause of diseases classified to other chapters
+∞
30.0
28
*
J01FF01
ATC
clindamycin; systemic
4.8
22.2
97
331
B95.7
ICD-10 Finland
Other staphylococcus as the cause of diseases classified to other chapters
+∞
21.2
20
*
B95.4
ICD-10 Finland
Other streptococcus as the cause of diseases classified to other chapters
+∞
21.2
20
*
A49.9
ICD-10 Finland
Bacterial infection, unspecified
6.0
18.6
56
122
I33.0
ICD-10 Finland
Acute and subacute infective endocarditis
104.7
17.9
19
*
A41.9
ICD-10 Finland
Sepsis, unspecified
13.4
16.7
29
25
A41.0
ICD-10 Finland
Sepsis due to Staphylococcus aureus
17.7
16.2
25
16
J04AB02
ATC
rifampicin; systemic
23.3
15.0
21
10
B95.3
ICD-10 Finland
Streptococcus pneumoniae as the cause of diseases classified to other chapters
161.6
14.7
15
*
C03CA01
ATC
furosemide; systemic
3.4
13.5
85
360
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
6.4
12.7
34
62
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
3.9
11.8
54
175
J01MA12
ATC
levofloxacin; systemic
3.7
11.7
60
211
B95.5
ICD-10 Finland
Unspecified streptococcus as the cause of diseases classified to other chapters
+∞
11.6
11
*
XF400
NOMESCO Finland
ECG with 12 standard connections
3.6
10.6
53
183
J01CF02
ATC
cloxacillin; systemic
10.5
10.5
20
21
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
4.2
10.2
40
112
L02.4
ICD-10 Finland
Cutaneous abscess, furuncle and carbuncle of limb
7.5
10.0
23
34
R50.9
ICD-10 Finland
Fever, unspecified
3.6
9.9
48
161
A10AC01
ATC
insulin (human); parenteral (insulins and analog. for injection, intermediate-acting)
4.8
9.8
33
79
123
Kela drug reimbursment
Chronic disorders of vitamin D metabolism
9.9
9.8
19
21
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
3.6
9.8
48
163
A46
ICD-10 Finland
Erysipelas
3.6
9.8
48
163
M46.4
ICD-10 Finland
Discitis, unspecified
58.0
9.7
11
*
FM1BE
NOMESCO Finland
Cardiac ultrasound examination through oesophagus
4.9
9.7
32
75
TPH20
NOMESCO Finland
Insertion of central venous catheter through subclavian or brachiocephalic vein
9.8
9.3
18
20
E10.7
ICD-10 Finland
Type 1 diabetes mellitus, With multiple complications
10.8
9.2
17
17
QDB10
NOMESCO Finland
Major dressing of wound of skin of lower limb
6.2
9.1
24
43
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
3.1
8.9
56
226
TK800
NOMESCO Finland
Hemodialysis
9.7
8.7
17
19
N18.8
ICD-10 Finland
Other chronic renal failure
8.5
8.6
18
23
TPH30
NOMESCO Finland
Insertion of central venous catheter through periferal vein
13.6
8.5
14
11
201
Kela drug reimbursment
Chronic cardiac insufficiency
5.9
8.5
23
43
J01MA14
ATC
moxifloxacin; systemic
4.4
8.5
31
81
127
Kela drug reimbursment
Transplant complication
10.1
8.5
16
17
B95.1
ICD-10 Finland
Streptococcus, group B, as the cause of diseases classified to other chapters
+∞
8.4
8
*
WX408
NOMESCO Finland
General anesthesy, balanced
2.7
8.2
71
345
WW200
NOMESCO Finland
Immunization
7.8
8.2
18
25
A40.8
ICD-10 Finland
Other streptococcal sepsis
34.9
8.2
10
*
Y83
ICD-10 Finland
Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
4.3
8.1
30
79
V03AE01
ATC
polystyrene sulfonate; oral
23.2
8.1
11
5
138
Kela drug reimbursment
Severe anaemia associated with chronic renal failure
8.4
8.1
17
22
J01CF05
ATC
flucloxacillin; systemic
6.2
7.8
20
35
TQW11
NOMESCO Finland
Vacuum treatment of wound
12.6
7.7
13
11
QDB99
NOMESCO Finland
Other procedure for wound of skin of lower limb
26.2
7.6
10
*
L97
ICD-10 Finland
Ulcer of lower limb, not elsewhere classified
6.5
7.6
19
32
QDB05
NOMESCO Finland
Revision of wound of skin of lower limb
7.3
7.5
17
25
I33.9
ICD-10 Finland
Acute endocarditis, unspecified
+∞
7.3
7
*
J01MA02
ATC
ciprofloxacin; systemic
2.3
7.3
88
506
L30.4
ICD-10 Finland
Erythema intertrigo
31.3
7.2
9
*
ZXM00
NOMESCO Finland
Intraoperative use of ultrasonographic imaging
21.0
7.2
10
5
PBL10
NOMESCO Finland
Construction of arteriovenous fistula from radial artery
12.7
7.2
12
10
TPH04
NOMESCO Finland
Cathetrisation of vein
2.7
7.2
55
249
Z49.1
ICD-10 Finland
Extracorporeal dialysis
10.6
7.1
13
13
L04AA01
ATC
[U] ciclosporin; systemic
10.6
7.1
13
13
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
3.3
7.1
37
130
R4110
NOMESCO Finland
Physiotherapy
2.5
7.0
67
342
A10AA02
ATC
NA
6.1
7.0
18
32
NHQ40
NOMESCO Finland
Amputation of toe
9.9
6.9
13
14
190
Kela drug reimbursment
Lanthanum carbonate, sevelamer and sucroferric oxyhydroxide
17.5
6.8
10
6
TPH07
NOMESCO Finland
Cathetrisation of artery
3.3
6.8
34
117
A11CC03
ATC
alfacalcidol; systemic
7.3
6.7
15
22
A10AB04
ATC
insulin lispro; parenteral (insulins and analog. for injection, fast-acting)
6.1
6.6
17
30
B01AB05
ATC
enoxaparin; parenteral
2.4
6.5
69
367
A12AA04
ATC
calcium carbonate; oral
8.6
6.4
13
16
A10AE04
ATC
insulin glargine; parenteral
3.5
6.3
29
93
V03AE02
ATC
sevelamer; oral
18.8
6.3
9
5
J18.9
ICD-10 Finland
Pneumonia, unspecified
2.4
6.3
61
311
B95.2
ICD-10 Finland
Streptococcus group D and enterococcus as the cause of diseases classified to other chapters
+∞
6.3
6
*
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
2.8
6.3
40
162
TPX10
NOMESCO Finland
Implantation of vascular injection port
7.1
6.2
14
21
J01EE01
ATC
sulfamethoxazole and trimethoprim; systemic
4.1
6.1
23
62
Z94.0
ICD-10 Finland
Kidney transplant status
10.5
6.1
11
11
M04AA01
ATC
allopurinol; systemic
3.0
6.1
35
132

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
75
227
4.62
23.32
3.3
2.3
—
—
—
0
0
36
69
6.11
18.73
2.1
2.1
1.7
1.6
g/l
0.29
30
56
58
191
3.83
15.42
3.1
1.7
—
—
—
0
0
87
443
2.67
10.43
12.0
4.3
—
—
—
0
0
58
248
2.86
9.66
4.1
2.4
20.6
24.3
%
0.90
52
218
60
277
2.65
8.51
2.7
1.8
—
—
—
0
0
96
557
2.35
8.26
14.6
5.7
—
—
—
0
0
45
185
2.83
7.94
5.2
3.2
2.3
1.7
%
2.80
39
171
71
367
2.43
7.87
3.0
2.1
3.0
3.0
mg/l
0.01
62
325
41
166
2.84
7.42
11.8
4.1
5.6
5.7
kpa
0.22
41
161
39
154
2.89
7.38
12.0
9.3
—
—
—
0
0
108
683
2.22
7.31
12.5
5.0
33.5
35.8
g/l
2.71
103
639
76
421
2.28
7.07
26.1
7.4
—
—
—
0
0
105
664
2.19
7.03
4.8
2.6
148.2
128.9
ug/l
0.38
96
613
40
167
2.73
6.81
12.1
4.3
—
—
—
0
0
125
868
2.12
6.33
15.4
6.1
1.7
1.9
e9/l
2.31
118
762
26
93
3.06
5.82
10.7
4.4
23.3
23.9
mmol/l
0.49
26
86
13
28
4.89
5.82
7.9
3.1
—
—
—
0
0
80
482
2.08
5.81
5.7
2.4
—
—
—
0
0
99
647
2.02
5.74
17.3
8.2
1.5
1.2
inr
1.33
26
199
120
847
2.00
5.52
15.6
6.0
0.6
0.6
e9/l
0.84
112
730
120
850
1.99
5.43
15.7
6.0
0.0
0.0
e9/l
0.85
113
735
41
196
2.36
5.22
1.7
1.6
—
—
—
0
0
10
19
5.48
5.09
1.8
1.2
—
—
—
0
0
121
873
1.94
5.04
17.4
6.3
0.2
0.2
e9/l
0.21
114
769
15
41
3.87
5.02
2.7
4.1
—
—
—
0
0
44
223
2.24
4.88
2.1
1.6
—
—
—
0
0
49
260
2.16
4.86
4.5
2.0
31.8
29.5
s
1.68
49
255
12
29
4.33
4.69
2.2
1.4
—
—
—
0
0
12
29
4.33
4.69
2.2
1.4
—
—
—
0
0
12
29
4.33
4.69
2.2
1.4
—
—
—
0
0
12
29
4.33
4.69
2.2
1.4
—
—
—
0
0
9
11
8.49
4.61
1.4
1.3
163.8
193.4
iu/ml
—
9
11
10
21
4.95
4.58
1.3
1.4
—
—
—
0
0
72
454
1.90
4.38
5.0
2.9
—
—
—
0
0
40
204
2.19
4.35
37.6
24.3
1.8
1.3
inr
—
7
26
74
473
1.88
4.31
5.4
2.9
0.7
0.4
e6/l
0.37
61
355
10
23
4.52
4.13
2.6
2.8
—
—
—
0
0
66
413
1.88
4.07
11.1
4.3
84.7
88.2
%
0.45
66
408
28
126
2.41
4.05
2.0
1.5
—
—
—
0
0
50
288
1.97
3.93
1.9
1.7
1163.3
1231.1
nmol/l
0.17
39
222
68
438
1.82
3.79
4.0
3.2
—
—
—
0
0
98
704
1.75
3.77
13.2
7.3
1.2
1.2
mmol/l
1.42
86
640
52
313
1.88
3.57
7.1
3.9
342.8
280.7
ng/l
0.11
41
249
12
36
3.48
3.53
2.4
1.6
—
—
—
0
0
105
779
1.71
3.52
17.7
7.8
1.2
1.2
mmol/l
0.47
91
664
16
58
2.91
3.51
2.4
1.2
—
—
—
0
0
15
53
2.97
3.44
4.9
2.7
—
—
—
0
0
36
197
2.00
3.24
5.5
10.6
-2.0
1.1
mmol/l
2.30
27
163
10
28
3.70
3.24
1.2
1.0
—
—
—
0
0
125
986
1.68
3.23
24.8
9.8
3.9
4.1
e9/l
0.58
120
860
58
373
1.77
3.19
1.6
1.5
19.5
20.5
nmol/l
0.20
50
311
75
519
1.70
3.18
6.4
3.2
908.7
173.4
e6/l
0.41
63
403
21
415
0.45
3.11
2.9
2.9
2.0
0.7
ug/l
0.40
14
270
11
34
3.36
3.10
1.2
1.1
—
—
—
0
0
69
473
1.69
3.00
12.4
4.2
7.4
7.4
ph
0.19
12
77
85
617
1.64
2.97
2.2
1.9
79.6
96.0
pmol/l
3.24
51
318
14
52
2.82
2.95
1.4
1.2
—
—
—
0
0
53
339
1.76
2.95
5.0
2.8
542.1
584.6
mosm/kgh2o
0.93
48
283
9
22
4.23
2.92
1.7
1.2
—
—
—
0
0
9
22
4.23
2.92
4.1
3.9
55.1
60.7
%
—
9
22
82
594
1.63
2.86
7.3
3.8
85.5
41.6
e6/l
0.70
65
426
9
23
4.04
2.81
7.3
2.2
65.9
59.2
%
—
9
23
20
92
2.30
2.77
6.9
14.7
—
—
—
0
0
97
744
1.57
2.61
22.9
9.6
0.0
0.0
e9/l
0.42
83
599
22
109
2.14
2.57
2.7
1.9
—
—
—
0
0
125
1022
1.57
2.51
6.3
4.4
—
337.1
—
0
22
7
16
4.49
2.49
4.4
3.0
—
—
—
0
0
8
21
3.92
2.49
4.4
3.1
5.6
4.4
e9/l
—
8
21
34
200
1.84
2.48
2.5
1.6
—
—
—
0
0
5
8
6.37
2.38
1.6
1.9
—
—
—
0
0
7
17
4.22
2.38
2.0
1.2
—
—
—
0
0
6
13
4.72
2.29
4.8
3.0
—
—
—
0
0
144
1619
0.63
2.26
5.1
4.9
2.5
2.7
mmol/l
1.62
129
1487
50
339
1.63
2.21
3.3
1.8
2.1
1.2
mg/l
0.43
42
261
8
24
3.42
2.20
2.9
2.1
—
—
—
0
0
9
30
3.09
2.17
1.1
1.2
—
—
—
0
0
51
350
1.61
2.15
1.9
1.5
2.8
2.6
g/l
0.28
35
213
10
37
2.79
2.13
1.9
1.4
—
—
—
0
0
8
25
3.29
2.12
1.6
1.4
—
—
—
0
0
9
31
2.99
2.10
2.0
2.0
—
11313.6
—
0
8
5
10
5.09
2.08
1.0
1.4
—
—
—
0
0
68
503
1.53
2.06
6.7
3.1
2.3
2.4
mmol/l
0.58
60
434
6
15
4.09
2.05
1.3
1.1
—
—
—
0
0
25
142
1.87
2.04
7.5
4.1
0.8
0.9
%
0.06
11
44
141
1579
0.66
1.95
4.6
4.4
1.3
1.4
mmol/l
1.55
124
1445
23
129
1.88
1.95
7.2
4.2
0.1
0.2
%
—
9
38
12
52
2.39
1.91
12.5
3.6
8.6
8.9
kpa
0.22
12
46
7
22
3.26
1.89
3.3
2.5
4.0
4.0
mmol/l
—
7
22
7
22
3.26
1.89
3.3
2.5
107.1
106.7
mmol/l
—
7
22
7
22
3.26
1.89
3.3
2.5
—
—
—
0
0
6
18
3.40
1.76
3.0
1.2
—
—
—
0
0
6
18
3.40
1.76
1.0
1.2
—
—
—
0
0
139
1542
0.70
1.58
4.7
4.5
6.2
6.0
mmol/l
0.95
124
1408
137
1523
0.70
1.57
4.4
4.0
1.4
1.3
mmol/l
0.66
121
1394
22
131
1.76
1.57
8.4
4.5
—
—
—
0
0
142
1254
1.43
1.55
20.4
8.0
96.9
81.0
u/l
2.52
135
1174
144
1585
0.70
1.53
4.8
4.5
4.4
4.6
mmol/l
1.54
130
1465
7
27
2.65
1.53
1.1
1.4
—
—
—
0
0
7
27
2.65
1.53
9.9
2.1
—
—
—
0
0
7
28
2.55
1.46
1.0
1.3
—
—
—
0
0
6
22
2.78
1.44
4.2
3.7
—
—
—
0
0
15
81
1.92
1.44
4.7
4.5
—
—
—
0
0
8
164
0.47
1.43
1.3
1.3
—
—
—
0
0
13
68
1.97
1.36
1.0
1.2
—
—
—
0
0
12
62
1.99
1.30
3.3
12.7
2.5
1.6
%
0.92
12
57
14
77
1.88
1.29
2.7
2.3
—
—
—
0
0
14
77
1.88
1.29
1.7
1.2
—
—
—
0
0
56
434
1.40
1.29
6.2
2.9
15504.4
7422.2
umol/l
0.22
51
372
9
45
2.04
1.25
1.6
1.5
—
—
—
0
0
10
49
2.09
1.24
1.5
1.1
—
—
—
0
0
19
118
1.67
1.20
3.2
8.3
—
—
—
0
0
6
26
2.35
1.19
1.0
1.5
—
—
—
0
0
18
112
1.67
1.13
10.2
7.7
22.9
24.7
mmol/l
0.75
18
112
135
1477
0.75
1.13
8.1
5.9
42.5
40.4
mmol/mol
1.12
121
1375
47
596
0.73
1.12
3.1
2.9
—
—
—
0
0
31
221
1.47
1.11
1.1
1.3
—
—
—
0
0
16
98
1.69
1.07
5.4
2.5
—
—
—
0
0
9
47
1.96
1.03
3.9
16.1
1.2
1.2
mmol/l
—
9
42
9
47
1.96
1.03
4.0
6.0
—
—
—
0
0
49
387
1.35
1.00
3.2
3.6
—
—
—
0
0
19
126
1.56
0.95
1.2
1.2
—
—
—
0
0
34
440
0.73
0.91
6.6
3.4
—
—
—
0
0
8
43
1.89
0.88
1.1
1.4
—
60.0
—
0
7
14
88
1.63
0.87
9.1
4.4
—
—
—
0
0
57
680
0.78
0.86
4.1
4.9
3.0
2.5
ug/l
0.11
50
606
47
381
1.30
0.81
10.3
5.4
—
—
—
0
0
10
59
1.73
0.77
2.0
1.4
—
—
—
0
0
6
34
1.79
0.77
2.0
1.2
—
—
—
0
0
6
34
1.79
0.77
1.8
2.2
—
—
—
0
0
54
451
1.27
0.74
5.5
3.3
1295.0
331.3
mg/l
0.38
39
303
9
56
1.63
0.73
1.7
2.7
—
—
—
0
0
5
25
2.02
0.73
1.8
2.0
—
—
—
0
0
57
480
1.26
0.73
6.9
4.1
23.1
7.8
mg/mmol
1.06
41
317
52
434
1.27
0.72
4.0
4.0
—
—
—
0
0
10
61
1.67
0.70
2.0
1.3
—
—
—
0
0
166
1736
0.77
0.69
24.2
10.6
29.4
27.1
u/l
0.89
160
1672
7
43
1.65
0.67
1.7
1.6
—
—
—
0
0
164
1716
0.78
0.67
26.2
13.2
—
—
—
0
0
57
485
1.24
0.67
5.6
3.2
6.9
8.0
mmol/l
1.06
46
408
5
28
1.80
0.66
1.0
1.3
—
—
—
0
0
5
28
1.80
0.66
7.8
2.3
—
—
—
0
0
17
121
1.44
0.64
2.8
1.5
—
—
—
0
0
5
29
1.74
0.64
5.4
2.6
4.8
4.9
kpa
—
5
29
5
29
1.74
0.64
5.4
2.6
7.9
8.7
kpa
—
5
29
10
63
1.62
0.63
2.0
1.3
—
—
—
0
0
10
63
1.62
0.63
2.0
1.3
—
—
—
0
0
10
63
1.62
0.63
2.0
1.3
—
—
—
0
0
0
23
0.00
0.58
0.0
3.7
—
—
—
0
0
9
60
1.52
0.55
1.6
1.8
—
—
—
0
0
40
335
1.24
0.54
1.9
1.8
369.9
442.9
pmol/l
1.38
35
290
25
197
1.31
0.54
1.1
1.2
—
—
—
0
0
119
1106
1.18
0.53
6.9
4.1
—
—
—
0
0
6
40
1.51
0.52
6.2
2.0
0.5
0.7
nmol/l
—
6
33
29
353
0.79
0.51
3.9
4.3
1.0
1.0
kg/l
—
7
47
158
1508
1.20
0.50
41.3
15.2
36.0
40.5
%
4.48
116
1121
21
165
1.30
0.47
1.7
1.4
—
—
—
0
0
49
426
1.20
0.47
1.8
1.7
1.6
1.3
mmol/l
0.70
40
361
28
229
1.26
0.47
1.5
1.4
460.0
374.2
titre
—
8
48
129
1218
1.16
0.43
7.4
4.2
16.3
11.3
mm/h
2.56
118
1111
5
31
1.63
0.43
1.0
1.5
—
—
—
0
0
0
16
0.00
0.41
0.0
3.2
—
—
—
0
0
16
124
1.31
0.40
6.2
3.5
—
—
—
0
0
0
19
0.00
0.39
0.0
6.3
—
7.4
—
0
5
41
359
1.18
0.37
1.5
1.4
0.7
0.8
u/ml
—
7
89
5
76
0.65
0.36
1.0
1.1
—
—
—
0
0
166
1614
1.15
0.29
41.1
14.7
27.7
23.2
mg/l
1.18
151
1267
5
74
0.67
0.26
1.0
1.1
—
—
—
0
0
122
1172
1.10
0.25
4.0
3.8
14.5
14.8
pmol/l
0.43
112
1060
85
806
1.09
0.22
6.8
5.1
0.0
0.0
estimate
0.00
12
150
5
42
1.20
0.21
1.4
1.1
—
—
—
0
0
5
42
1.20
0.21
1.4
1.5
—
337.8
—
0
20
0
10
0.00
0.21
0.0
1.5
—
1.0
—
0
10
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
12
0.00
0.21
0.0
1.2
—
—
—
0
0
0
13
0.00
0.21
0.0
9.9
—
813.0
—
0
13
0
13
0.00
0.21
0.0
17.6
—
1308.8
—
0
13
64
605
1.08
0.18
2.1
2.0
—
—
—
0
0
7
62
1.13
0.17
5.0
5.7
—
—
—
0
0
30
273
1.12
0.17
1.2
1.3
4.0
6.3
u/ml
0.33
15
106
85
814
1.08
0.17
5.1
3.8
0.0
0.0
estimate
0.00
15
139
12
101
1.20
0.17
1.2
1.4
92.5
121.7
iu/ml
—
5
35
13
111
1.18
0.16
1.3
1.2
—
25.4
—
0
7
19
169
1.14
0.15
1.9
1.4
—
—
—
0
0
40
428
0.92
0.15
4.5
4.1
0.0
0.0
estimate
0.50
13
138
20
179
1.13
0.15
1.3
1.3
—
—
—
0
0
142
1445
0.94
0.11
4.9
4.5
1.9
1.9
mu/l
0.15
130
1310
14
126
1.12
0.09
2.3
2.3
—
7.9
—
0
5
82
803
1.04
0.06
4.6
3.7
0.0
0.0
estimate
0.00
12
147
114
1130
1.02
0.02
5.3
3.8
—
—
—
0
0
42
411
1.03
0.02
1.7
1.4
—
—
—
0
0
28
286
0.98
0.00
1.3
1.3
18.7
34.4
iu/ml
—
9
94
15
149
1.01
0.00
1.3
1.7
—
—
—
0
0
12
117
1.03
0.00
1.4
1.3
—
—
—
0
0
64
637
1.01
0.00
3.6
3.9
33.2
42.5
ng/l
0.34
45
443
14
142
0.98
0.00
1.7
1.4
—
—
—
0
0
13
132
0.98
0.00
2.7
3.8
—
—
—
0
0
0
8
0.00
0.00
0.0
2.3
—
—
—
0
0
0
8
0.00
0.00
0.0
2.1
—
3.2
—
0
8
0
8
0.00
0.00
0.0
6.0
—
—
—
0
0
0
8
0.00
0.00
0.0
1.5
—
—
—
0
0
0
9
0.00
0.00
0.0
1.8
—
—
—
0
0
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
1.5
—
—
—
0
0
8
82
0.97
0.00
1.5
1.2
—
—
—
0
0
0
6
0.00
0.00
0.0
2.7
—
—
—
0
0
0
6
0.00
0.00
0.0
4.2
—
—
—
0
0
0
5
0.00
0.00
0.0
1.6
—
38.2
—
0
5
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
0.8
—
0
5
0
6
0.00
0.00
0.0
4.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.3
—
94.4
—
0
6
0
5
0.00
0.00
0.0
3.4
—
4.3
—
0
5
0
5
0.00
0.00
0.0
2.4
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint AB1_STREPTSTAPHYCOCC_INOTHER and mortality.

Females

Parameter HR [95% CI] p-value
AB1_STREPTSTAPHYCOCC_INOTHER 2.548 [1.94, 3.35] < 0.001
Birth year 0.997 [0.99, 1.01] 0.489

During the follow-up period (1.1.1998 — 31.12.2019), 185 out of 872 females with AB1_STREPTSTAPHYCOCC_INOTHER died.

Males

Parameter HR [95% CI] p-value
AB1_STREPTSTAPHYCOCC_INOTHER 3.059 [2.4, 3.9] < 0.001
Birth year 0.986 [0.98, 1.0] 0.004

During the follow-up period (1.1.1998 — 31.12.2019), 310 out of 1147 males with AB1_STREPTSTAPHYCOCC_INOTHER died.

Mortality risk

Mortality risk for people of age

years, who have AB1_STREPTSTAPHYCOCC_INOTHER.

N-year risk Females Males
1 0.3% 0.628%
5 1.742% 3.201%
10 4.149% 8.239%
15 7.55% 15.117%
20 13.582% 24.671%

Relationships between endpoints

Index endpoint: AB1_STREPTSTAPHYCOCC_INOTHER – Streptococcus and staphylococcus as the cause of diseases classified to other chapters

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
loading spinner Loading data