No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleNone |
520210 |
2. Check conditionsNone |
520210 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
480 |
4. Check minimum number of eventsNone |
480 |
5. Include endpointsNone |
480 |
6. Filter based on genotype QC (FinnGen only) |
480 |
Control definitions (FinnGen only)
- Control exclude
- AB1_VIRAL_CNS
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF5
Similar endpoints
↥List of similar endpoints to
Acute poliomyelitis
based on the number of shared cases.
Similar with more cases:
- Viral infections of the central nervous system
- Certain infectious and parasitic diseases
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 4599 | 2621 | 1929 |
| Only index persons | 3668 | 2164 | 1504 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.07 | 0.08 | 0.05 |
| Only index persons | 0.07 | 0.08 | 0.06 |
| Median age at first event (years) | |||
| Whole population | 28.96 | 33.25 | 22.55 |
| Only index persons | 25.15 | 31.10 | 16.58 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 480 | 315 | 165 |
| Unadjusted period prevalence (%) | 0.10 | 0.11 | 0.07 |
| Median age at first event (years) | 28.03 | 28.67 | 26.81 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
No data
-FinnGen-
Cumulative Incidence Function
No data
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 442
- Matched controls
- 4417
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
04599
ICD-8 Finland
Aseptic mentingitis due to enterovirus, Aseptic meningitis, unspecified
+∞
227.3
198
*
04300
ICD-8 Finland
NA
+∞
69.7
65
*
04499
ICD-8 Finland
Late effects of actue poliomyelitis
+∞
50.0
47
*
04597
ICD-8 Finland
Aseptic mentingitis due to enterovirus, Suspecta
+∞
48.9
46
*
B91
ICD-10 Finland
Sequelae of poliomyelitis
94.9
32.2
35
*
1380A
ICD-9 Finland
Late effects of acute poliomyelitis[SEQUELAE POLIOMYELITIDIS]
115.5
20.8
22
*
04301
ICD-8 Finland
NA
+∞
14.7
14
*
04500
ICD-8 Finland
Aseptic mentingitis due to enterovirus, Coxsackie virus
+∞
13.6
13
*
N70
ICPC
Poliomyelitis
+∞
13.6
13
*
64090
ICD-8 Finland
Artificial termination of pregnancy performed for medical reasons, Woman's illness or physical defect (medicines. Cause)
10.1
12.4
24
25
32099
ICD-8 Finland
Meningitis, With no organism specified as cause
41.1
10.0
12
*
N06AA09
ATC
amitriptyline; systemic
2.5
7.9
65
288
N93
ICPC
Carpal tunnel syndrome
12.5
6.6
11
9
J01DA01
ATC
[U] cefalexin; systemic
1.7
6.6
277
2201
32088
ICD-8 Finland
Meningitis, Alia definita
+∞
6.3
6
*
0459X
ICD-9 Finland
Acute poliomyelitis, unspecified[POLIOMYELITIS ACUTA NUD,NUD]
+∞
6.3
6
*
Mortality – FinRegistry
↥Association
Association between endpoint AB1_POLIOMYELITIS and mortality.
Females
No dataMales
No dataMortality risk
Mortality risk for people of age
years, who have AB1_POLIOMYELITIS.| N-year risk | Females | Males |
|---|---|---|
| 1 | No data | No data |
| 5 | No data | No data |
| 10 | No data | No data |
| 15 | No data | No data |
| 20 | No data | No data |
Relationships between endpoints
↥Index endpoint: AB1_POLIOMYELITIS – Acute poliomyelitis
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
Loading data