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Alzheimer’s disease (Atypical or mixed)

AD_AM

Alzheimer's disease: A progressive, neurodegenerative disease characterized by loss of function and death of nerve cells in several areas of the brain leading to loss of cognitive function such as memory and language.

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Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

2 out of 7 registries used, show all original rules.

3491

4. Check minimum number of events

None

3491

5. Include endpoints

None

3491

6. Filter based on genotype QC (FinnGen only)

3491

Control definitions (FinnGen only)

Control exclude
G6_ALZHEIMER

Extra metadata

First used in FinnGen datafreeze
DF2

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

All Female Male
Number of individuals 3491 1503 1988
Unadjusted period prevalence (%) 0.72 0.51 0.88
Median age at first event (years) 81.80 82.22 81.48

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
2771
Matched controls
27665
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
N06DA02
ATC
donepezil; oral
27.7
323.0
1065
609
F00.20*G30.8
ICD-10 Finland
Dementia in Alzheimer's disease, atypical or mixed type without additional symptoms
202.8
323.0
1460
151
G30.8
ICD-10 Finland
Other Alzheimer disease
476.8
323.0
1891
124
N06DA03
ATC
rivastigmine; oral, transdermal
25.5
323.0
794
428
307
Kela drug reimbursment
Tacrine, donepezil, rivastigmine, galantamine and other major and expensive drugs used to treat Alzheimer's disease
65.6
323.0
1230
332
P20
ICPC
Memory disturbance
6.2
323.0
1238
3181
N06DX01
ATC
memantine; oral
46.6
323.0
1594
781
G30.9
ICD-10 Finland
Alzheimer disease, unspecified
146.1
323.0
676
61
G30.1
ICD-10 Finland
Alzheimer disease with late onset
28.4
323.0
775
373
F00.20
ICD-10 Finland
Dementia in Alzheimer's disease, atypical or mixed type without additional symptoms
67.5
323.0
496
89
N05AX08
ATC
risperidone; systemic
10.2
323.0
863
1172
N06DA04
ATC
galantamine; oral
20.6
290.0
446
255
F00.10*G30.1
ICD-10 Finland
Primary degenerative dementia of the Alzheimer's type, senile onset without additional symptoms
24.5
244.7
354
164
SPAT1053
SPAT
Memory test
4.0
217.9
1155
4182
N05AH04
ATC
quetiapine; oral
5.6
209.6
694
1545
P70
ICPC
Dementia
14.2
204.3
362
289
F0029, G308
ICD-10 Finland
NA
+∞
191.8
182
*
F03
ICD-10 Finland
Unspecified dementia
5.9
191.6
602
1244
R41.8
ICD-10 Finland
Other and unspecified symptoms and signs involving cognitive functions and awareness
4.5
142.5
579
1542
G30
ICD-10 Finland
Alzheimer disease
32.5
113.5
151
49
G30.0
ICD-10 Finland
Alzheimer disease with early onset
239.3
112.5
115
5
SPAT1245
SPAT
Provision of support and information to patient’s family members
4.5
108.5
425
1069
R53
ICD-10 Finland
Malaise and fatigue
2.7
108.3
957
4480
F009, G309
ICD-10 Finland
NA
+∞
102.7
98
*
SPAT1216
SPAT
Assessment of functional ability
2.7
99.5
860
3932
SPAT1234
SPAT
Support of social functional capacity
4.1
97.5
423
1165
AA1AD
NOMESCO Finland
CT of head and brain
2.5
96.8
1057
5497
SPAT1217
SPAT
Assessment of need for services (elderly/care support)
3.1
95.1
616
2328
F00.00*G30.0
ICD-10 Finland
Primary degenerative dementia of the Alzheimer's type, presenile onset without additional symptoms
248.0
94.1
96
*
A28
ICPC
Limited function/disability NOS
2.5
87.8
932
4714
N05BA04
ATC
oxazepam; oral
2.5
87.6
882
4337
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
2.2
84.0
1235
7297
F0019, G301
ICD-10 Finland
NA
+∞
83.7
80
*
SPAT1222
SPAT
Counselling/guidance promoting independent living
2.5
77.9
778
3762
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
2.4
77.8
902
4710
F05.1
ICD-10 Finland
Delirium superimposed on dementia
17.7
76.0
121
71
SPAT1137
SPAT
Taking care of patient’s/customer’s hygiene
3.0
75.8
503
1902
N06AX11
ATC
mirtazapine; oral
2.3
73.4
941
5129
N02BE01
ATC
paracetamol; systemic, rectal
2.4
71.7
2313
18734
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
2.4
66.4
719
3576
F06.7
ICD-10 Finland
Mild cognitive disorder
4.8
66.0
232
512
SPAT1254
SPAT
Administration of medicine
2.3
63.0
698
3496
N06AB10
ATC
escitalopram; oral
2.9
62.6
436
1685
F00.10
ICD-10 Finland
Primary degenerative dementia of the Alzheimer's type, senile onset without additional symptoms
10.6
60.7
121
119
R41.0
ICD-10 Finland
Disorientation, unspecified
4.0
58.5
255
691
J18.9
ICD-10 Finland
Pneumonia, unspecified
2.0
57.9
1155
7386
SPAT1301
SPAT
No procedures
2.0
57.0
1056
6553
WYA30
NOMESCO Finland
Preparations for expected poor cooperation
3.4
54.7
288
911
F00.9
ICD-10 Finland
Dementia in Alzheimer disease, unspecified
21.6
54.1
80
38
F00.24
ICD-10 Finland
Dementia in Alzheimer's disease, atypical or mixed type other additional symptoms of mixed type
179.7
51.0
53
*
SPAT1306
SPAT
Counselling and guidance related to nutrition and weight management
2.4
50.9
501
2334
N05AH03
ATC
olanzapine; systemic
5.4
50.6
158
304
F0024, G308
ICD-10 Finland
NA
+∞
50.1
48
*
N03AG01
ATC
valproic acid; systemic, rectal
4.2
47.1
188
469
F002, G308
ICD-10 Finland
NA
127.0
46.9
50
*
A04
ICPC
Weakness/tiredness general
2.2
46.2
526
2617
U04
ICPC
Incontinence urine
3.2
43.6
251
843
SPAT1229
SPAT
Assessment of need for aid
2.4
42.5
408
1866
SPAT1292
SPAT
Other function in accordance with SHToL (Finnish classification of nursing interventions)
2.5
41.7
374
1647
F0009, G300
ICD-10 Finland
NA
+∞
40.7
39
*
L28
ICPC
Limited function/disability (L)
1.9
40.2
702
4141
A06AD11
ATC
lactulose; oral
1.9
38.4
745
4551
S06.0
ICD-10 Finland
Concussion
2.4
36.2
343
1550
N02AA05
ATC
oxycodone; systemic
1.9
35.8
610
3544
I69.3
ICD-10 Finland
Sequelae of cerebral infarction
2.1
35.6
440
2252
G91.2
ICD-10 Finland
Normal-pressure hydrocephalus
5.2
35.5
114
227
SPAT1101
SPAT
Orthostatic test
2.6
35.5
271
1089
R41.3
ICD-10 Finland
Other amnesia
3.9
35.3
151
401
N05BA06
ATC
lorazepam; systemic, sublingual
2.9
34.9
228
831
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
1.9
34.7
575
3303
Z03.3
ICD-10 Finland
Observation for suspected nervous system disorder
3.0
33.9
214
762
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
1.9
33.9
636
3816
SAD01
NOMESCO Finland
Assessment of need for oral health care, standard
2.7
33.1
241
939
F0022, G308
ICD-10 Finland
NA
+∞
32.3
31
*
SPAT1263
SPAT
Sampling
1.6
31.3
1104
7972
SPAT1304
SPAT
Counselling and guidance related to ageing
2.1
31.3
391
2001
SPAT1253
SPAT
Initiation, adjustment, discontinuation or repetition of medication
1.7
30.6
875
5956
SPAT1360
SPAT
Extensive global examination
2.4
30.4
285
1274
G31.8
ICD-10 Finland
Other specified degenerative diseases of nervous system
9.4
30.3
63
68
SPAT1252
SPAT
Overall medication plan or its review
2.3
29.4
306
1440
AA1BG
NOMESCO Finland
Standard MRI examination of brain with high intensity magnet
3.0
29.1
179
628
S01.0
ICD-10 Finland
Open wound of scalp
2.3
29.0
286
1313
R55
ICD-10 Finland
Syncope and collapse
1.9
28.8
449
2502
F0014, G301
ICD-10 Finland
NA
+∞
28.1
27
*
F0021, G308
ICD-10 Finland
NA
+∞
28.1
27
*
F00.2
ICD-10 Finland
Dementia in Alzheimer disease, atypical or mixed type
146.2
27.6
29
*
I95.1
ICD-10 Finland
Orthostatic hypotension
2.6
27.6
210
839
C10AA01
ATC
simvastatin; oral
1.6
27.4
1533
12273
J01DB01
ATC
cefalexin; oral
1.6
27.3
1866
15666
WYA20
NOMESCO Finland
Home visit
4.1
27.1
108
270
N39.0
ICD-10 Finland
Urinary tract infection, site not specified
1.8
26.4
559
3453
W19
ICD-10 Finland
Unspecified fall
2.1
26.4
325
1647
SPAT1251
SPAT
Organisation of medication
2.6
25.7
199
803
112
Kela drug reimbursment
Severe psychotic and other severe mental disorders
2.8
25.6
175
655
130
Kela drug reimbursment
Malignant tumour
0.3
25.6
55
1777
F32.9
ICD-10 Finland
Depressive episode, unspecified
2.5
25.5
207
859
Z02.4
ICD-10 Finland
Examination for driving licence
0.5
24.6
282
4845
S70.0
ICD-10 Finland
Contusion of hip
2.6
23.5
178
709
B01AC30
ATC
platelet aggregation inhibitors excl. heparin - combinations
1.9
23.5
353
1930
SPAT1250
SPAT
Comprehensive monitoring of chronic illness
1.6
23.5
853
6089
N30.0
ICD-10 Finland
Acute cystitis
1.8
23.0
458
2761
E86
ICD-10 Finland
Volume depletion
3.0
23.0
139
483
F0023, G308
ICD-10 Finland
NA
+∞
22.9
22
*
N06AB04
ATC
citalopram; systemic
1.7
22.6
523
3303
I63.9
ICD-10 Finland
Cerebral infarction, unspecified
1.7
22.3
543
3476
F00.00
ICD-10 Finland
Primary degenerative dementia of the Alzheimer's type, presenile onset without additional symptoms
35.3
22.0
28
8
SPAT1231
SPAT
Assessment of adjustments needed in living environment
3.0
22.0
128
434
AAF05
NOMESCO Finland
Ventriculoperitoneal shunt
4.6
21.9
77
171
F0024, G301
ICD-10 Finland
NA
+∞
21.9
21
*
S72.0
ICD-10 Finland
Fracture of neck of femur
2.1
21.8
251
1229
SPAT1305
SPAT
Counselling and guidance related to physical exercise
2.0
21.7
314
1689
R42
ICD-10 Finland
Dizziness and giddiness
1.6
21.6
725
5055
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
1.6
21.5
747
5251
SPAT1156
SPAT
Guidance concerning treatment of rash and skin
1.7
21.4
480
2997
TAB00
NOMESCO Finland
Lumbar puncture
3.9
21.1
89
235
SPAT1172
SPAT
Guidance concerning hydration
2.6
21.1
159
630
A10AB05
ATC
insulin aspart; parenteral (insulins and analog. for injection, fast-acting)
2.1
20.2
240
1193
N06AX26
ATC
vortioxetine; oral
3.4
20.2
100
302
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
1.5
19.6
1003
7665
Z75.5
ICD-10 Finland
Holiday relief care
4.0
19.1
78
201
A98
ICPC
Health maint/preventive medicine
1.5
18.9
1942
16989
SPAT1246
SPAT
Screening of depression or other psychiatric problem
3.7
18.9
83
228
SPAT1262
SPAT
Handing over of treatment supplies
1.6
18.5
504
3311
N05AD01
ATC
haloperidol; systemic
2.6
18.5
143
576
A10AE04
ATC
insulin glargine; parenteral
1.9
18.2
286
1584
J01CA08
ATC
pivmecillinam; oral
1.5
18.1
968
7426
NFB20
NOMESCO Finland
Primary partial prosthetic replacement of hip joint using cement, other or unspecified
2.3
18.0
165
728
F00
ICD-10 Finland
Dementia in Alzheimer disease
10.7
17.9
34
32
F05.9
ICD-10 Finland
Delirium, unspecified
2.8
17.3
111
402
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
2.1
17.1
196
960
SPAT1220
SPAT
Assessment of need for rehabilitation and/or rehabilitation plan
2.0
17.0
221
1140
F00.22
ICD-10 Finland
Dementia in Alzheimer's disease, atypical or mixed type other additional symptoms, mainly hallucinations
40.2
16.3
20
5
F29
ICD-10 Finland
Unspecified nonorganic psychosis
4.8
16.1
53
111
B03BA03
ATC
hydroxocobalamin; parenteral
1.9
16.1
257
1431
F00.21
ICD-10 Finland
Dementia in Alzheimer's disease, atypical or mixed type of other additional symptoms, mainly paranoidism
30.1
16.1
21
7
F00.14
ICD-10 Finland
Primary degenerative dementia of the Alzheimer's type, senile onset other additional symptoms of mixed type
21.0
15.9
23
11
SAB01
NOMESCO Finland
Restricted oral and dental health check by dental hygienist or dental assistant
2.3
15.3
149
675
SPAT1279
SPAT
Preparation of immediate hospitalisation
3.2
15.0
80
258
SPAT1249
SPAT
Treatment-related counselling outside office
1.4
14.7
849
6550
N06AX16
ATC
venlafaxine; oral
2.1
14.7
169
830
H02AB02
ATC
dexamethasone; systemic
0.4
14.6
49
1299
F009, G308
ICD-10 Finland
NA
+∞
14.6
14
*
SPAT1307
SPAT
Psychosocial counselling and guidance
3.3
14.5
72
220
R56.8
ICD-10 Finland
Other and unspecified convulsions
2.4
14.4
124
531
SAD02
NOMESCO Finland
Assessment of need for oral health care, extensive
3.7
14.2
62
171
A49.9
ICD-10 Finland
Bacterial infection, unspecified
1.6
14.1
376
2444
F00.19
ICD-10 Finland
Dementia in Alzheimer's disease with late onset without information about additional symptoms
30.1
13.9
18
6
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
1.7
13.8
319
1992
R99
ICD-10 Finland
Other ill-defined and unspecified causes of mortality
2.7
13.6
94
358
G45.9
ICD-10 Finland
Transient cerebral ischaemic attack, unspecified
1.7
13.6
324
2043
G04CA02
ATC
tamsulosin; oral
1.4
13.4
845
6600
SPAT1284
SPAT
Extensive health certificate
3.0
13.3
77
263
SPAT1167
SPAT
Insertion of urinary catheter
2.0
13.0
157
789
E0000UV
ATC
NA
1.4
12.9
830
6497
F21
ICPC
NA
3.3
12.9
64
197
G40.9
ICD-10 Finland
Epilepsy, unspecified
2.4
12.4
100
417
I10
ICD-10 Finland
Essential (primary) hypertension
1.3
12.3
1781
15819
XA800
NOMESCO Finland
Neuropsychological investigation
3.5
12.2
57
167
SPAT1050
SPAT
Extensive neurological examination
2.8
12.2
80
294
H25.1
ICD-10 Finland
Senile nuclear cataract
1.3
12.2
1181
9860
Z29
ICPC
Social problem NOS
3.2
12.2
63
200
A29
ICPC
General symptom/complaint other
1.6
12.0
318
2063
NF1AA
NOMESCO Finland
Hip X-ray examination
1.6
12.0
292
1853
SPAT1256
SPAT
Intramuscular and subcutaneous injection
1.4
11.9
964
7822
A10AE05
ATC
insulin detemir; parenteral
2.0
11.7
147
751
R50.9
ICD-10 Finland
Fever, unspecified
1.6
11.7
339
2249
R1250
NOMESCO Finland
Evaluation of functional capability
3.4
11.6
54
159
SPAT1139
SPAT
Nutrition survey
2.2
11.6
114
525
N04BA02
ATC
levodopa and decarboxylase inhibitor; oral
1.9
11.5
162
862
I25.9
ICD-10 Finland
Chronic ischaemic heart disease, unspecified
1.4
11.4
542
3995
F0011, G301
ICD-10 Finland
NA
120.3
11.4
12
*
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
1.5
11.2
398
2761
J01EA01
ATC
trimethoprim; systemic
1.4
11.2
749
5875
G40.22
ICD-10 Finland
Complex partial epileptic seizure with secondary generalization
3.2
11.2
57
180
S01CA01
ATC
dexamethasone and antiinfectives; ophthalmic (ophth., corticosteroids and antiinfectives in comb.)
1.3
11.1
1172
9862
Z51.5
ICD-10 Finland
Palliative care
1.7
11.1
217
1288
J69.0
ICD-10 Finland
Pneumonitis due to food and vomit
2.4
11.1
92
390
N05AH02
ATC
clozapine; systemic
9.2
11.0
22
24
-1
ICPC
NA
2.9
10.9
64
222
Z51.88
ICD-10 Finland
Other specified medical care
2.9
10.9
65
229
E000001
ATC
NA
1.5
10.7
449
3226
NE1AA
NOMESCO Finland
Pelvis X-ray examination
1.7
10.7
225
1366
F00.23
ICD-10 Finland
Dementia in Alzheimer's disease, atypical or mixed type of other additional symptoms, mainly depression
28.1
10.7
14
5
111
Kela drug reimbursment
Epilepsy and comparable convulsive disorders
2.0
10.7
137
703
J22
ICD-10 Finland
Unspecified acute lower respiratory infection
2.1
10.6
121
595
R33
ICD-10 Finland
Retention of urine
1.5
10.3
319
2146
N18
ICPC
Paralysis/weakness
2.6
10.2
73
286
A03FA01
ATC
metoclopramide; systemic, rectal
0.7
10.1
248
3623
G04CB02
ATC
dutasteride; oral
1.6
10.0
231
1445
ZX012
NOMESCO Finland
Radiotherapy with large shaped fields - isocentric therapy
0.4
9.9
29
811
C03CA01
ATC
furosemide; systemic
1.3
9.8
1358
11795
F00.1
ICD-10 Finland
Dementia in Alzheimer disease with late onset
20.1
9.8
14
7
SPAT1276
SPAT
Outlining of treatment with patient or their family members
2.3
9.8
85
368
F01.20
ICD-10 Finland
Subcortical vascular dementia without additional symptoms
3.6
9.8
42
117
N40
ICD-10 Finland
Hyperplasia of prostate
1.3
9.8
752
6011
213
Kela drug reimbursment
Fat metabolism disorder associated with chronic coronary artery disease
1.5
9.6
380
2695
NF1BA
NOMESCO Finland
Hip extensive X-ray examination
2.0
9.6
116
586
S06.5
ICD-10 Finland
Traumatic subdural haemorrhage
1.9
9.5
140
762
L89
ICD-10 Finland
Decubitus ulcer and pressure area
2.4
9.4
78
333
F00.29
ICD-10 Finland
Dementia in Alzheimer's disease, atypical or mixed type without information on additional symptoms
30.1
9.4
12
*
S97
ICPC
Chronic ulcer skin
1.7
9.4
179
1057
WD105
NOMESCO Finland
Cystostatic therapy of methastized malignancy
0.2
9.3
7
409
R44.1
ICD-10 Finland
Visual hallucinations
4.4
9.3
32
73
N30.9
ICD-10 Finland
Cystitis, unspecified
1.7
9.1
181
1083
A10BA02
ATC
metformin; oral
1.3
9.0
794
6460
K90
ICPC
Stroke/cerebrovascular accident
2.0
9.0
112
573
215
Kela drug reimbursment
Diabetes, non-insulin-treated
1.4
9.0
527
4022
KMAK
NOMESCO Finland
NA
1.3
8.9
736
5929
SPAT1260
SPAT
Consultation of another employee
1.4
8.9
407
2971
J01CA04
ATC
amoxicillin; systemic
1.3
8.9
1646
14764
A01
ICPC
Pain general/multiple sites
1.7
8.8
189
1153
SPAT1157
SPAT
Guidance concerning treatment of mouth and mucous membranes
2.8
8.8
53
189
Z50.9
ICD-10 Finland
Care involving use of rehabilitation procedure, unspecified
2.2
8.8
90
425
J01MA02
ATC
ciprofloxacin; systemic
1.3
8.8
1034
8751
N02AJ06
ATC
codeine and paracetamol; systemic
0.7
8.8
349
4682
Z25.8
ICD-10 Finland
Need for immunization against other specified single viral diseases
0.4
8.7
46
1020
SPAT1226
SPAT
Implementation of occupational therapy rehabilitation plan
2.0
8.7
103
516
E11.9
ICD-10 Finland
Type 2 diabetes mellitus, without complications
1.3
8.6
736
5953
U07.1
ICD-10 Finland
Emergency use of U07.1 | COVID-19, virus identified
1.8
8.6
138
772
A69
ICPC
General and Unspecified, Other reason for encounter NEC
2.1
8.5
93
451
A10BB12
ATC
glimepiride; oral
1.5
8.5
309
2151
C08CA01
ATC
amlodipine; oral
1.3
8.5
1072
9138
F10.1
ICD-10 Finland
Mental and behavioural disorders due to use of alcohol, Harmful use
2.0
8.4
97
482
F0289, G318
ICD-10 Finland
NA
90.1
8.4
9
*
NB6AA
NOMESCO Finland
Humerus X-ray examination
2.5
8.4
61
243
F0013, G301
ICD-10 Finland
NA
+∞
8.3
8
*
F0010, G308
ICD-10 Finland
NA
+∞
8.3
8
*
G04CB01
ATC
finasteride; oral (testosterone-5-alpha reductase inhibitors)
1.4
8.3
453
3415
N06AB06
ATC
sertraline; oral
1.8
8.3
137
774
R44.3
ICD-10 Finland
Hallucinations, unspecified
4.4
8.2
28
64
G72.8
ICD-10 Finland
Other specified myopathies
2.5
8.2
61
247
DFF00
NOMESCO Finland
Pure tone audiometry
0.5
8.2
80
1455
F05.0
ICD-10 Finland
Delirium not superimposed on dementia, so described
5.1
8.1
24
47
G40.29
ICD-10 Finland
Localization-related (focal)(partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures
2.6
8.1
54
206
W06
ICD-10 Finland
Fall involving bed
3.1
8.1
42
137
F22.0
ICD-10 Finland
Delusional disorder
3.0
8.0
46
157
H02AA02
ATC
fludrocortisone; oral
3.1
8.0
41
133
N06AX21
ATC
duloxetine; oral
1.7
7.9
162
977
SPAT1148
SPAT
Treatment of chronic ulcer or burn
1.4
7.9
423
3175
A04AA02
ATC
granisetron; systemic, transdermal
0.3
7.9
18
562
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
1.3
7.8
1035
8850
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
2.1
7.8
83
399
NFJ54
NOMESCO Finland
Internal fixation of fracture of upper femur with intramedullary nail
2.1
7.8
89
440
N05AX12
ATC
aripiprazole; systemic
4.8
7.7
24
50
SPAT1215
SPAT
Assessment of need for medical rehabilitation
1.9
7.7
108
578
F32
ICD-10 Finland
Depressive episode
2.4
7.7
64
275
F10.73
ICD-10 Finland
Residual or late-onset psychosis caused by alcohol dementia
15.0
7.7
12
8
C09AA05
ATC
ramipril; oral
1.3
7.6
810
6731
I67.3
ICD-10 Finland
Progressive vascular leukoencephalopathy
2.5
7.6
57
232
T90
ICPC
Diabetes non-insulin dependent
1.3
7.6
544
4280
EBA15
NOMESCO Finland
Extraction of large number of teeth
2.1
7.6
83
404
F02.89
ICD-10 Finland
Dementia in another specified disease that is classified elsewhere without information of additional symptoms
25.0
7.6
10
*
Z60.8
ICD-10 Finland
Other problems related to social environment
5.1
7.5
22
43
J15.9
ICD-10 Finland
Bacterial pneumonia, unspecified
1.4
7.5
333
2415
F01.9
ICD-10 Finland
Vascular dementia, unspecified
1.9
7.5
100
526
L76
ICPC
Fracture: other
2.0
7.3
86
431
E11.8
ICD-10 Finland
Type 2 diabetes mellitus, with unspecified complications
1.4
7.3
298
2122
N99
ICPC
Neurological disease other
3.1
7.3
37
120
C34.1
ICD-10 Finland
Malignant neoplasm: Upper lobe, bronchus or lung
0.3
7.2
12
441
G04CA01
ATC
alfuzosin; oral
1.4
7.2
333
2432
G91.0
ICD-10 Finland
Communicating hydrocephalus
4.3
7.2
25
59
Z28
ICPC
Limited function/disability (Z)
3.9
7.0
27
70
SPAT1221
SPAT
Guidance concerning rehabilitation services and livelihood
2.8
7.0
42
151
WD125
NOMESCO Finland
Demanding cystostatic therapy of methastized malignancy
0.3
6.9
10
392
C01DA08
ATC
isosorbide dinitrate; oral, oral aerosol, sublingual, transdermal
1.3
6.9
918
7825
S72.1
ICD-10 Finland
Pertrochanteric fracture
1.8
6.9
118
677
N05AB03
ATC
perphenazine; systemic, rectal
2.2
6.9
66
303
Z87.1
ICD-10 Finland
Personal history of diseases of the digestive system
0.7
6.9
354
4582
SPAT1081
SPAT
Cardiorespiratory global assessment
1.6
6.9
162
1022
4912B
ICD-9 Finland
Chronic bronchitis, Obstructive chronic bronchitis[BRONCHITIS OBSTRUCTIVA CUM EMPHYSEMATE]
0.2
6.8
6
315
N39.9
ICD-10 Finland
Disorder of urinary system, unspecified
2.2
6.8
63
284
JN3AA
NOMESCO Finland
Abdominal X-ray examination without contrast
1.7
6.8
143
871
F009, F03
ICD-10 Finland
NA
10.9
6.8
12
11
AXX01
SPAT
NA
2.7
6.8
44
166
X59
ICD-10 Finland
Exposure to unspecified factor
1.4
6.8
337
2496
N07AA05
ATC
NA
40.1
6.7
8
*
R23.8
ICD-10 Finland
Other and unspecified skin changes
0.7
6.7
162
2382
NA1AD
NOMESCO Finland
Cervical spine CT examination
1.9
6.7
93
498
-
ICD-10 Finland
NA
2.2
6.6
64
295
LC2BE
NOMESCO Finland
Transvaginal ultrasound examination of uterus, parametria and lower abdomen
0.6
6.6
124
1917
SPAT1111
SPAT
Planning of analgesia
2.7
6.6
43
163
Z02.7
ICD-10 Finland
Issue of medical certificate
1.6
6.6
146
907
SPAT1293
SPAT
Other function in accordance with rehabilitation guidance nomenclature
4.0
6.6
24
60
LAITO
NOMESCO Finland
NA
8.7
6.5
13
15
ZX120
NOMESCO Finland
Intravenous
0.6
6.5
90
1495
S32.0
ICD-10 Finland
Fracture of lumbar vertebra
1.8
6.5
104
586
EB1SA
NOMESCO Finland
Dental X-ray, bite-wing X-ray on one side of the mouth
0.7
6.5
196
2767
SPAT1325
SPAT
Vaccination
1.2
6.5
921
7900
WX111
NOMESCO Finland
Local infiltration anesthesia
0.2
6.4
7
323
SPAT1296
SPAT
Other function in accordance with occupational therapy nomenclature
2.5
6.4
46
184
A10BH05
ATC
linagliptin; oral
1.6
6.4
165
1063
G04BD08
ATC
solifenacin; oral
1.5
6.4
193
1293
R81
ICPC
Pneumonia
2.0
6.4
77
394
8070/3-C34.9
ICD-O-3
Squamous cell carcinoma, NOS, of lung, NOS
0.2
6.3
5
282
EBA00
NOMESCO Finland
Extraction of tooth
1.3
6.3
518
4143
P29
ICPC
Psychological sympt/compl other
2.4
6.3
51
216
N28
ICPC
Limited function/disability (N)
2.4
6.3
51
216
F0021, G301
ICD-10 Finland
NA
+∞
6.2
6
*
F0014, G308
ICD-10 Finland
NA
+∞
6.2
6
*
R03DA04
ATC
theophylline; systemic, rectal
0.6
6.2
112
1750
N05AD03
ATC
melperone; systemic
2.3
6.2
56
250
AAF20
NOMESCO Finland
Revision of shunt of ventricle of brain
4.3
6.2
21
49
WX402
NOMESCO Finland
General anaesthesia
0.6
6.2
78
1324
Z01.9
ICD-10 Finland
Special examination, unspecified
1.8
6.1
106
612
UKC02
NOMESCO Finland
Cystoscopy
1.3
6.1
511
4096
G46.8*I67.9
ICD-10 Finland
Other vascular syndromes of brain in cerebrovascular diseases
5.7
6.1
16
28
C07AB07
ATC
bisoprolol; oral
1.2
6.1
1480
13403
M01AC06
ATC
meloxicam; systemic, rectal
1.3
6.1
687
5724
F05.8
ICD-10 Finland
Other delirium
2.9
6.1
33
113
N29
ICPC
Neurological sympt/complt other
2.3
6.1
50
215
G25.9
ICD-10 Finland
Extrapyramidal and movement disorder, unspecified
2.9
6.1
35
122
SPAT1125
SPAT
Stoma care and guidance
2.0
6.1
70
351

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
1427
7398
2.56
150.89
2.2
1.9
1397.97
1161.45
nmol/l
15.55
1020
5453
1138
6463
2.12
86.47
6.1
5.1
0.00
0.00
estimate
0.50
257
2025
1142
6649
2.06
79.97
1.9
1.8
457.37
7466541.53
pmol/l
1.53
860
5237
88
97
9.25
72.40
1.0
1.1
589.94
689.29
ng/l
0.76
48
48
88
97
9.25
72.40
1.0
1.1
380.00
268.57
ng/l
1.83
52
51
921
5409
1.95
59.86
6.6
5.3
1.02
1.02
kg/l
0.24
88
966
2242
17426
1.79
56.48
7.3
5.9
3559.27
2697.64
e6/l
0.36
128
334
110
206
5.47
55.77
2.6
3.3
299.43
332.57
umol/l
1.59
82
166
1498
10506
1.74
53.03
4.5
3.9
—
—
—
0
0
1610
11759
1.68
47.30
5.1
4.9
56.45
81.41
ng/l
0.89
1327
9638
480
2441
2.11
45.43
4.7
3.9
—
—
—
0
0
1322
9357
1.66
42.49
2.6
3.0
2.34
2.35
mmol/l
1.46
1096
7737
1321
9349
1.66
42.47
4.0
4.2
—
—
—
0
0
593
3334
1.93
42.16
12.8
10.4
—
—
—
0
0
1318
9486
1.62
38.63
5.4
4.4
—
5.94
—
0
9
1622
12310
1.59
37.77
4.0
4.1
33.57
33.58
g/l
0.05
1397
11120
1565
11794
1.59
37.46
5.7
4.7
0.00
0.00
estimate
0.00
296
2207
2576
21869
1.67
36.98
22.2
20.6
31.99
29.24
mg/l
3.19
2252
18749
1576
11935
1.58
36.68
5.8
4.8
0.00
0.00
estimate
0.00
292
2172
1190
8486
1.60
35.48
2.4
2.1
258.71
228.24
u/l
0.60
1062
7853
1540
11764
1.55
33.44
6.8
6.4
0.00
0.00
estimate
0.00
286
2162
107
298
3.66
32.86
1.3
1.3
35.76
39.36
e6/l
0.04
91
246
107
299
3.65
32.70
1.3
1.4
470.47
990.92
e6/l
0.53
93
252
118
355
3.40
32.23
1.2
1.3
522.92
647.77
mg/l
0.81
104
337
105
308
3.47
29.84
1.2
1.3
3.99
4.01
mmol/l
0.04
98
279
380
2054
1.95
29.74
4.6
5.5
24.47
24.52
mmol/l
0.08
360
1915
855
5841
1.61
29.44
3.1
3.0
2.46
2.47
mmol/l
4.01
747
4929
2625
22868
1.58
28.99
26.5
25.5
4.04
4.03
mmol/l
0.62
2449
22085
2623
22853
1.58
28.88
26.5
25.3
139.49
139.25
mmol/l
3.23
2453
22108
2630
22950
1.58
28.54
30.3
29.9
30.28
30.39
pg
1.84
2477
22306
2630
22950
1.58
28.54
30.4
30.0
236.05
233.28
e9/l
1.10
2460
22035
2630
22952
1.58
28.50
30.5
30.0
4.17
4.24
e12/l
9.28
2452
21919
2630
22952
1.58
28.50
30.4
29.9
91.90
92.12
fl
1.31
2477
22311
2630
22957
1.58
28.43
30.7
30.3
125.49
127.87
g/l
12.27
2482
22343
2630
22960
1.58
28.38
30.5
30.0
7.52
7.23
e9/l
3.04
2455
21923
1781
14343
1.49
28.27
5.1
6.2
1.21
1.21
mmol/l
0.54
1323
11853
528
3233
1.74
27.51
2.8
2.6
5.20
5.45
ug/l
0.14
381
2616
2502
21668
1.53
27.32
22.7
20.2
—
—
—
0
0
1608
12813
1.47
26.17
4.7
5.6
1.21
1.21
mmol/l
0.44
1389
11364
589
8718
0.61
26.06
2.2
2.4
—
—
—
0
0
1125
8417
1.49
24.87
3.2
3.7
7.40
7.40
ph
0.77
250
1595
2033
17126
1.44
23.53
5.7
5.2
—
—
—
0
0
206
990
2.14
22.16
2.7
3.5
3.89
3.92
mmol/l
0.30
177
912
2253
19511
1.43
21.23
4.6
4.9
2.10
2.14
mu/l
0.27
1894
17030
1260
9858
1.43
21.21
2.1
2.2
77.29
80.56
nmol/l
3.42
999
8299
1848
15499
1.40
20.67
5.0
4.7
7.35
6.99
mmol/l
6.69
1733
14558
280
4762
0.55
20.27
1.5
1.5
1.21
1.24
mmol/l
0.40
226
3879
1516
12393
1.39
19.22
2.4
2.2
84.59
91.88
pmol/l
7.81
800
6393
828
6111
1.46
18.60
5.0
4.6
—
—
—
0
0
223
1182
1.94
18.33
2.6
3.3
1.46
1.41
mmol/l
0.28
217
1159
1874
15957
1.37
18.00
3.7
3.8
15.63
15.37
pmol/l
3.68
1554
13835
239
1315
1.87
17.54
3.3
4.1
—
—
—
0
0
357
2232
1.66
16.81
3.2
3.7
—
—
—
0
0
78
272
2.90
16.75
1.2
1.3
—
—
—
0
0
2053
18072
1.32
14.05
22.7
22.5
34.69
36.16
%
2.98
705
9860
94
2041
0.44
14.02
1.2
1.3
—
—
—
0
0
1880
16399
1.31
13.48
29.9
27.7
329.38
329.42
g/l
0.05
1811
16081
414
2843
1.51
12.94
3.8
6.0
118.68
117.96
g/l
0.30
399
2736
318
2074
1.58
12.53
5.1
4.9
—
—
—
0
0
746
5742
1.38
12.52
6.2
4.5
—
—
—
0
0
369
2502
1.53
12.22
3.5
3.6
1.23
1.22
mmol/l
1.24
284
2148
1475
12598
1.29
11.78
13.6
13.0
1.39
1.45
inr
1.31
418
3307
453
3244
1.45
11.42
3.6
5.5
94.80
94.92
%
0.14
435
3079
182
3004
0.58
11.40
1.4
1.4
—
—
—
0
0
2433
22272
1.29
10.69
8.7
11.0
22.28
22.32
u/l
0.01
2177
21037
979
8012
1.30
10.56
2.2
2.4
59.97
59.51
u/l
0.06
860
7325
120
626
1.94
10.43
4.2
5.3
11.65
11.20
mmol/l
0.54
108
552
120
626
1.94
10.43
4.2
5.3
104.54
104.56
mmol/l
0.02
108
552
158
906
1.77
10.20
4.2
4.8
1.54
1.39
mmol/l
0.60
140
792
62
1389
0.44
10.06
1.5
1.6
—
—
—
0
0
134
735
1.85
10.02
3.8
4.6
2.53
2.91
mmol/l
0.84
85
494
134
736
1.85
9.97
3.8
4.7
4.96
5.03
kpa
0.37
126
715
134
737
1.85
9.93
3.8
4.7
7.88
8.12
kpa
1.01
126
716
28
72
3.90
9.80
1.5
1.3
—
—
—
0
0
68
292
2.35
9.76
3.6
3.3
—
—
—
0
0
1896
16931
1.26
9.73
3.7
4.2
17.61
17.12
mm/h
0.50
1603
15231
2059
18568
1.26
9.67
5.3
7.0
83.70
84.63
u/l
0.21
1800
17137
1028
8562
1.28
9.49
2.4
2.4
3.38
3.30
mg/l
0.36
815
7159
935
7709
1.29
9.32
1.7
1.7
19.67
19.68
nmol/l
0.00
816
6466
786
6348
1.30
9.16
3.2
2.8
5.55
5.12
e6/l
0.47
724
5587
32
95
3.38
9.12
1.1
1.2
0.80
1.11
promille
0.62
24
73
473
6157
0.73
9.08
3.3
3.9
76.98
78.08
%
0.39
447
5982
143
835
1.74
8.72
3.7
4.5
7.42
7.42
ph
0.31
126
716
478
6172
0.74
8.66
2.3
2.5
—
—
—
0
0
480
3669
1.35
8.15
3.6
5.3
1.45
1.22
mmol/l
0.54
340
2761
34
113
3.02
8.10
1.4
1.3
—
—
—
0
0
252
1721
1.50
8.06
4.1
3.0
0.58
0.35
e6/l
0.46
246
1693
674
8217
0.77
7.96
3.1
3.8
14.34
10.54
mg/mmol
0.98
413
5223
163
2509
0.63
7.62
1.1
1.2
19.03
16.75
u/ml
0.10
49
801
931
10802
0.81
6.97
4.5
5.1
61.27
60.61
%
0.79
820
9810
122
732
1.69
6.82
3.7
3.9
35.13
31.69
mg/l
0.50
102
513
632
7629
0.79
6.70
2.6
3.1
687.33
315.22
mg/l
0.88
393
4922
187
2715
0.67
6.62
1.1
1.2
54.07
41.72
iu/ml
0.36
51
835
634
7618
0.79
6.42
2.4
3.0
6.71
6.51
mmol/l
0.64
483
6033
93
527
1.78
6.38
1.8
1.9
1.76
1.72
mmol/l
0.15
93
512
829
9658
0.81
6.31
11.7
10.8
0.00
0.00
e9/l
2.49
692
7717
942
10827
0.82
6.27
4.5
5.1
2.75
2.74
%
0.05
829
9826
80
438
1.84
6.16
11.8
11.1
8.85
7.51
mmol/l
1.53
67
353
949
10875
0.82
6.08
4.9
5.4
9.15
9.01
%
0.51
838
9882
7
308
0.23
5.99
1.6
1.7
—
—
—
0
0
210
2901
0.70
5.69
1.1
1.3
—
—
—
0
0
460
3671
1.29
5.69
3.7
5.3
10.83
11.36
kpa
1.72
433
3402
460
3671
1.29
5.69
3.7
5.3
4.93
5.03
kpa
1.49
434
3408
139
2072
0.66
5.63
1.2
1.2
338.46
519.75
titre
1.09
26
485
225
3059
0.72
5.55
1.6
1.4
2.99
2.86
g/l
0.15
111
1638
927
10555
0.83
5.40
4.5
5.1
0.55
0.59
%
1.45
817
9587
974
11038
0.83
5.39
4.8
5.4
23.10
23.95
%
1.39
856
9958
389
4840
0.78
5.18
1.3
1.3
—
—
—
0
0
204
1467
1.41
5.06
1.6
1.7
2.51
2.36
ug/l
0.05
151
1210
106
1633
0.64
5.04
4.6
6.7
23.80
24.39
mmol/l
0.72
92
1462
428
5224
0.79
4.84
2.8
3.4
1.03
0.91
ug/l
0.50
309
3863
22
78
2.82
4.78
1.5
1.4
—
—
—
0
0
31
131
2.37
4.78
1.3
1.3
—
—
—
0
0
136
1963
0.68
4.72
3.7
3.6
0.12
0.11
%
0.07
34
596
78
1268
0.60
4.69
1.7
2.1
10.12
10.44
g/l
0.24
54
1026
1717
15808
1.16
4.66
4.8
4.8
—
—
—
0
0
247
3217
0.75
4.62
2.5
3.5
12.19
23.41
ug/l
1.03
195
2719
1249
11231
1.17
4.58
3.3
3.5
2442.74
2534.17
ng/l
0.21
1020
9791
1049
9308
1.18
4.53
4.5
5.8
9.10
5.64
ug/l
0.27
839
8101
725
8329
0.83
4.51
2.4
2.7
—
—
—
0
0
162
1145
1.43
4.47
1.3
1.3
—
—
—
0
0
512
4256
1.23
4.45
2.3
2.2
1.74
1.77
%
0.29
384
3650
15
428
0.35
4.44
1.1
1.1
—
—
—
0
0
67
1115
0.59
4.44
1.1
1.2
—
—
—
0
0
126
1821
0.68
4.42
3.3
3.5
0.32
0.66
%
1.84
19
439
1782
16504
1.16
4.34
24.8
24.8
14.24
14.23
%
0.20
1708
15989
159
2195
0.71
4.33
1.2
1.3
—
—
—
0
0
1468
13418
1.16
4.25
3.8
5.3
12.27
12.95
umol/l
1.06
1286
12610
148
2060
0.70
4.23
3.7
3.6
0.75
0.93
%
0.43
38
641
62
1035
0.59
4.18
1.8
2.5
34.11
5437.24
u/ml
1.28
36
875
47
251
1.88
4.03
1.6
1.3
—
—
—
0
0
47
251
1.88
4.03
1.6
1.3
—
—
—
0
0
47
251
1.88
4.03
1.6
1.3
—
—
—
0
0
47
251
1.88
4.03
1.6
1.3
—
—
—
0
0
75
461
1.64
3.97
1.5
2.1
25.68
32.53
umol/l
2.05
56
352
996
8880
1.17
3.96
3.9
3.6
195.67
141.06
e6/l
0.20
821
6977
244
1893
1.31
3.78
2.9
3.3
25.40
24.98
mmol/l
1.25
231
1837
1094
9875
1.15
3.63
4.5
4.1
274.46
144.70
e6/l
1.29
874
7386
722
8159
0.85
3.60
4.3
4.9
—
—
—
0
0
497
4212
1.21
3.56
3.4
4.3
—
—
—
0
0
84
1256
0.66
3.56
1.2
1.2
—
—
—
0
0
65
1027
0.62
3.55
1.5
2.0
34.93
36.02
g/l
0.69
46
820
167
2211
0.74
3.54
2.0
2.4
30.18
35.81
u/l
1.64
132
1840
265
2103
1.28
3.48
2.8
3.1
128.53
123.90
g/l
2.83
257
2059
393
4674
0.82
3.47
3.6
3.3
2.36
2.65
e6/l
0.33
223
2685
108
746
1.46
3.44
12.3
14.6
—
—
—
0
0
130
1778
0.72
3.40
3.6
3.6
0.02
0.31
%
0.93
29
481
109
759
1.45
3.34
3.5
3.8
—
—
—
0
0
7
223
0.31
3.31
1.0
1.2
—
—
—
0
0
8
237
0.34
3.30
1.4
1.2
—
—
—
0
0
606
5268
1.18
3.26
34.1
35.1
1.70
1.61
inr
0.38
52
668
152
1127
1.36
3.25
1.7
2.1
544.50
519.40
ug/l
0.07
135
1067
39
212
1.84
3.23
1.4
2.1
7.43
7.42
ph
—
6
84
65
1000
0.64
3.19
2.9
2.2
—
—
—
0
0
183
1401
1.32
3.17
3.8
4.0
1.65
1.51
%
2.02
170
1319
54
857
0.62
3.05
2.1
3.3
189.33
115.08
u/ml
0.42
48
817
20
86
2.33
3.05
1.2
1.0
123.65
135.77
nmol/l
0.33
20
86
6
192
0.31
2.93
1.0
1.1
—
—
—
0
0
37
205
1.81
2.92
1.7
1.5
—
—
—
0
0
179
1386
1.30
2.88
3.9
4.1
0.94
0.85
%
2.24
167
1302
7
13
5.38
2.86
1.1
1.4
—
—
—
0
0
15
345
0.43
2.84
3.3
3.3
—
—
—
0
0
237
1909
1.26
2.80
4.2
3.9
—
—
—
0
0
205
1627
1.27
2.74
2.2
2.4
0.72
0.67
%
1.28
195
1563
234
1887
1.25
2.74
1.6
1.9
405.01
393.17
nmol/l
0.40
187
1656
111
1498
0.73
2.73
1.4
1.4
—
—
—
0
0
7
14
4.99
2.72
1.0
1.1
—
—
—
0
0
16
68
2.35
2.54
1.1
1.5
19.18
15.73
pmol/l
1.31
11
50
18
81
2.22
2.52
1.1
1.2
73.91
70.08
%
0.19
11
66
203
1630
1.26
2.49
3.9
5.9
24.44
24.91
mmol/l
0.85
195
1609
34
194
1.75
2.48
1.3
1.7
—
—
—
0
0
99
722
1.38
2.43
2.4
2.6
15.78
15.23
%
0.71
35
376
142
1813
0.77
2.40
1.8
1.6
1.65
1.52
g/l
0.84
103
1529
141
1801
0.77
2.39
1.6
1.8
317.19
178.21
ug/g
1.11
89
1360
7
17
4.11
2.35
1.1
1.2
—
—
—
0
0
125
952
1.32
2.33
2.9
2.8
4.18
4.26
pmol/l
0.38
102
790
7
18
3.88
2.24
1.0
1.1
—
—
—
0
0
591
6562
0.88
2.23
2.6
2.9
2516.09
9316.16
umol/l
5.05
439
5349
511
5728
0.87
2.22
4.7
5.9
—
—
—
0
0
17
337
0.50
2.21
1.5
1.4
—
—
—
0
0
155
1227
1.27
2.18
3.7
3.2
0.83
0.83
nmol/l
0.10
119
930
438
4950
0.87
2.14
3.0
3.1
1.59
1.43
e6/l
0.44
266
2935
7
19
3.68
2.14
1.0
1.1
—
—
—
0
0
53
354
1.50
2.12
1.1
1.2
—
—
—
0
0
18
341
0.52
2.06
1.3
1.1
—
—
—
0
0
7
20
3.49
2.05
1.0
1.1
—
—
—
0
0
7
20
3.49
2.05
1.0
1.1
—
—
—
0
0
7
20
3.49
2.05
1.0
1.1
—
—
—
0
0
6
15
3.99
2.03
1.5
1.3
—
—
—
0
0
7
174
0.40
2.03
1.3
1.8
—
—
—
0
0
288
2456
1.18
2.00
1.5
1.9
0.19
0.19
g/l
0.66
246
2216
23
401
0.57
1.99
1.3
1.3
—
—
—
0
0
77
1035
0.74
1.93
1.2
1.5
—
12.42
—
0
26
1797
18701
0.91
1.93
3.5
4.1
1.22
1.22
mmol/l
0.09
1405
15992
2142
20587
1.10
1.93
4.4
5.3
6.29
6.18
mmol/l
1.95
1688
17754
257
2997
0.84
1.89
4.6
4.7
—
—
—
0
0
369
3232
1.15
1.84
1.7
1.8
—
—
—
0
0
6
17
3.52
1.83
1.0
1.1
—
—
—
0
0
109
1383
0.78
1.82
2.8
2.6
11.65
10.98
g/l
0.45
84
1229
148
1812
0.81
1.82
5.0
4.6
—
—
—
0
0
50
342
1.46
1.82
4.7
5.5
13.90
12.94
mg/l
0.52
42
299
506
4535
1.13
1.81
1.6
1.8
29.78
30.49
s
1.42
483
4361
1862
19312
0.92
1.80
3.9
4.6
1.41
1.42
mmol/l
0.97
1482
16732
34
522
0.65
1.79
5.6
3.8
1.77
1.49
%
0.25
22
374
193
2294
0.83
1.77
1.4
1.4
—
—
—
0
0
183
1516
1.21
1.77
4.9
7.5
—
—
—
0
0
1044
11099
0.91
1.76
4.4
4.5
—
—
—
0
0
1254
11812
1.09
1.72
2.8
3.0
57.84
58.48
u/l
0.07
1035
10439
1066
11310
0.91
1.71
3.9
4.8
0.63
0.65
e9/l
0.75
900
9397
432
3850
1.14
1.69
3.8
5.5
103.99
104.05
mmol/l
0.09
396
3755
687
6291
1.11
1.69
3.4
3.1
544.71
539.38
mosm/kgh2o
0.34
600
5346
0
48
0.00
1.69
0.0
1.3
—
—
—
0
0
1075
11396
0.91
1.69
3.9
4.8
0.04
0.04
e9/l
0.98
917
9490
359
3166
1.15
1.65
2.4
2.3
64.98
66.13
e9/l
0.27
269
2460
40
582
0.68
1.64
3.5
2.5
—
—
—
0
0
16
83
1.93
1.63
1.1
1.4
80.29
109.29
umol/l
—
7
52
5
130
0.38
1.62
1.4
1.7
0.65
0.90
e9/l
—
5
83
117
1447
0.80
1.61
2.8
3.8
—
—
—
0
0
86
661
1.30
1.60
1.2
1.2
—
—
—
0
0
60
804
0.74
1.54
1.4
1.2
—
—
—
0
0
11
215
0.51
1.46
1.0
1.1
—
—
—
0
0
7
28
2.50
1.44
1.1
1.3
—
—
—
0
0
26
163
1.59
1.44
2.4
2.0
1.87
2.95
u/field
0.69
15
104
41
577
0.71
1.44
1.0
1.1
—
—
—
0
0
12
226
0.53
1.42
1.0
1.0
—
—
—
0
0
75
960
0.77
1.41
3.1
3.7
—
—
—
0
0
315
2788
1.14
1.40
2.7
2.9
4.04
4.29
kpa
1.94
304
2669
23
141
1.63
1.40
1.0
1.0
—
—
—
0
0
1062
10018
1.08
1.36
2.6
2.9
167.89
154.10
ug/l
0.65
878
8843
13
235
0.55
1.36
4.5
2.8
8.47
11.69
nmol/l
0.31
13
226
12
222
0.54
1.35
1.0
1.1
—
—
—
0
0
774
8248
0.92
1.34
4.5
5.0
—
—
—
0
0
59
774
0.76
1.34
1.1
1.1
24.74
102.47
iu/ml
6.31
21
254
0
38
0.00
1.34
0.0
1.1
—
14.29
—
0
17
27
176
1.53
1.30
1.1
1.1
—
—
—
0
0
60
454
1.32
1.29
2.0
3.4
62.85
61.60
%
0.27
60
454
9
174
0.51
1.28
2.8
3.1
—
—
—
0
0
21
129
1.63
1.28
5.9
4.6
—
—
—
0
0
44
598
0.73
1.28
1.6
2.2
—
—
—
0
0
44
598
0.73
1.28
1.7
1.6
—
—
—
0
0
6
130
0.46
1.28
1.0
1.1
—
132.80
—
0
25
6
134
0.45
1.27
1.3
1.4
—
—
—
0
0
126
1501
0.83
1.26
2.5
3.2
23.98
24.03
mmol/l
0.06
109
1324
10
190
0.52
1.24
1.2
1.5
—
—
—
0
0
399
4366
0.90
1.21
2.5
2.5
0.81
0.81
mmol/l
0.08
349
3932
318
3524
0.89
1.21
1.2
1.2
1.30
1.51
u/ml
0.26
93
847
1121
11727
0.93
1.21
4.0
4.9
0.21
0.20
e9/l
0.63
946
9883
100
1212
0.82
1.20
3.1
4.2
24.62
24.80
mmol/l
0.18
73
1060
1109
11601
0.93
1.19
4.0
5.0
1.66
1.82
e9/l
2.09
949
9813
0
33
0.00
1.16
0.0
1.1
—
—
—
0
0
0
33
0.00
1.16
0.0
13.9
—
5.13
—
0
33
0
33
0.00
1.16
0.0
1.1
—
—
—
0
0
85
1042
0.81
1.15
2.8
2.6
0.37
0.31
g/l
0.22
29
377
91
1107
0.81
1.15
1.9
1.8
1.03
1.54
g/l
1.97
64
967
10
184
0.54
1.14
1.3
1.1
—
30.81
—
0
9
122
1435
0.84
1.09
1.5
1.5
—
—
—
0
0
10
181
0.55
1.09
1.3
1.8
2.33
3.23
ug/l
—
10
157
26
374
0.69
1.09
1.7
2.4
—
—
—
0
0
8
41
1.95
1.08
25.6
29.0
97.25
102.61
ug/l
—
8
36
18
277
0.65
1.05
1.2
1.2
—
—
—
0
0
13
216
0.60
1.05
1.2
1.2
—
—
—
0
0
12
203
0.59
1.04
1.2
1.2
—
—
—
0
0
8
148
0.54
1.03
1.3
1.3
—
—
—
0
0
85
696
1.22
1.02
1.8
2.3
68.03
92.10
ug/min
0.34
35
395
304
2748
1.11
1.01
3.1
5.0
1.65
1.48
mmol/l
1.21
284
2585
13
213
0.61
1.00
1.0
1.1
—
—
—
0
0
1912
19571
0.94
0.99
3.9
4.6
4.13
4.23
mmol/l
3.84
1542
17153
271
2438
1.12
0.99
2.4
3.2
99.09
100.94
ng/l
0.10
186
1971
29
400
0.72
0.98
1.0
1.1
—
754.62
—
0
13
0
29
0.00
0.97
0.0
1.1
—
—
—
0
0
36
479
0.75
0.97
1.3
1.5
—
—
—
0
0
37
490
0.75
0.97
1.4
1.7
12.45
13.83
mg/l
0.29
29
444
11
186
0.59
0.96
1.5
1.8
—
—
—
0
0
21
305
0.68
0.95
2.2
2.7
—
—
—
0
0
106
895
1.19
0.95
2.9
3.2
24.75
24.97
mmol/l
0.22
94
766
34
250
1.36
0.94
1.1
1.3
144123.43
194252.72
e6/l
0.17
23
162
9
51
1.76
0.94
1.1
1.2
—
—
—
0
0
255
2810
0.90
0.93
4.1
5.1
12.67
13.07
mmol/l
0.30
218
2593
101
1185
0.85
0.92
1.3
1.2
—
—
—
0
0
21
142
1.48
0.91
5.9
4.3
—
—
—
0
0
92
772
1.19
0.89
1.2
1.4
—
—
—
0
0
429
4601
0.92
0.89
3.6
3.6
—
—
—
0
0
5
102
0.49
0.89
1.4
1.7
68.00
70.95
%
—
5
93
26
185
1.40
0.88
1.2
1.3
—
—
—
0
0
14
87
1.61
0.86
2.1
1.7
—
—
—
0
0
11
179
0.61
0.85
3.9
2.3
—
—
—
0
0
11
179
0.61
0.85
1.0
1.2
—
—
—
0
0
56
689
0.81
0.85
1.6
1.7
21.69
21.94
s
0.12
45
639
12
72
1.66
0.84
1.1
1.2
—
—
—
0
0
38
489
0.77
0.84
1.3
1.2
39.27
53.54
u/l
0.38
33
419
1999
20378
0.95
0.83
4.3
5.3
2.29
2.39
mmol/l
6.11
1610
17779
11
176
0.62
0.80
1.4
1.9
2.11
1.97
ug/l
0.09
11
141
37
474
0.78
0.80
1.3
1.4
—
—
—
0
0
161
1427
1.13
0.79
1.3
1.4
—
—
—
0
0
43
338
1.27
0.78
1.0
1.3
235.50
296.10
nmol/l
1.04
18
255
8
48
1.66
0.78
1.3
1.1
—
18.29
—
0
7
7
121
0.58
0.78
1.1
1.2
—
—
—
0
0
357
3307
1.09
0.76
2.8
3.3
1.98
1.95
mmol/l
0.05
283
2595
358
3320
1.08
0.74
2.8
3.3
5.91
5.81
kpa
1.05
344
3193
801
7638
1.06
0.74
3.6
3.5
—
—
—
0
0
5
24
2.08
0.74
16.8
7.2
0.47
0.61
mmol/l
—
5
24
34
434
0.78
0.73
1.4
1.5
—
—
—
0
0
156
1737
0.89
0.72
2.3
2.6
—
—
—
0
0
37
466
0.79
0.71
2.4
2.7
—
—
—
0
0
90
773
1.17
0.71
2.2
2.3
125.22
122.73
g/l
0.52
85
556
17
240
0.70
0.70
9.4
16.6
—
—
—
0
0
5
26
1.92
0.70
1.0
1.0
—
—
—
0
0
2039
19936
1.05
0.69
6.6
7.0
43.84
42.03
mmol/mol
8.49
1688
17636
127
1427
0.88
0.69
3.2
3.4
4.82
4.30
e9/l
0.86
73
917
106
1205
0.87
0.69
3.0
2.6
32.93
60.98
mg/l
1.63
75
975
5
95
0.52
0.66
1.6
2.2
—
—
—
0
0
42
515
0.81
0.66
1.3
1.4
93286.74
60601.78
e6/l
0.29
23
316
5
28
1.78
0.66
12.8
11.9
14.02
14.19
%
—
5
28
107
1208
0.88
0.64
3.0
2.6
61.33
114.70
mg/l
0.57
76
974
8
126
0.63
0.64
1.3
1.2
—
3.00
—
0
7
666
6350
1.06
0.63
2.5
2.7
32.97
36.70
u/l
1.01
601
5920
426
4499
0.94
0.63
2.4
2.5
19.59
20.35
%
0.48
279
3746
20
146
1.37
0.62
1.4
1.4
—
—
—
0
0
54
641
0.84
0.62
1.3
1.5
29.17
29.06
g/l
0.02
45
557
241
2599
0.92
0.62
3.5
6.0
—
—
—
0
0
11
71
1.55
0.61
1.4
1.5
—
—
—
0
0
39
477
0.81
0.61
1.5
1.6
—
—
—
0
0
24
311
0.77
0.60
1.1
1.2
—
—
—
0
0
79
683
1.16
0.60
2.5
2.9
—
—
—
0
0
0
20
0.00
0.60
0.0
2.1
—
142.86
—
0
7
44
361
1.22
0.60
1.3
1.3
—
—
—
0
0
0
22
0.00
0.59
0.0
1.1
—
—
—
0
0
7
112
0.62
0.58
1.3
1.4
17.43
17.25
umol/l
—
7
99
12
82
1.46
0.53
7.2
6.4
—
—
—
0
0
106
1179
0.89
0.53
2.9
2.6
5.87
3.63
ratio
—
10
88
11
74
1.48
0.52
2.7
1.9
57.17
57.87
umol/l
—
6
52
33
269
1.23
0.50
1.2
1.4
261.25
265.16
titre
—
8
31
10
144
0.69
0.49
1.6
1.8
163.60
197.04
pmol/l
—
10
133
270
2865
0.93
0.49
2.2
2.2
64.19
65.37
g/l
1.38
212
2471
14
189
0.74
0.48
1.1
1.2
—
—
—
0
0
102
1129
0.90
0.48
1.8
2.1
8.91
10.04
nmol/l
0.64
77
935
7
110
0.63
0.48
1.0
1.4
—
—
—
0
0
13
177
0.73
0.48
1.1
1.1
—
—
—
0
0
19
146
1.30
0.46
1.4
1.6
9.58
9.22
mmol/l
0.15
13
124
48
556
0.86
0.46
1.3
1.4
2106.03
1373.10
e6/l
0.92
36
408
71
627
1.13
0.44
1.2
1.2
—
—
—
0
0
28
229
1.22
0.43
1.2
1.3
13.57
23.30
%
1.73
17
148
624
6011
1.04
0.42
4.9
4.6
177.80
326.84
ng/l
1.52
573
5475
458
4758
0.95
0.42
2.1
2.4
2.18
2.23
g/l
1.02
373
4298
6
94
0.64
0.42
1.0
1.1
—
—
—
0
0
6
94
0.64
0.42
1.0
1.1
—
—
—
0
0
8
58
1.38
0.41
1.3
1.2
—
—
—
0
0
0
16
0.00
0.41
0.0
1.1
—
—
—
0
0
38
443
0.85
0.40
2.9
2.6
—
—
—
0
0
0
17
0.00
0.40
0.0
1.4
—
—
—
0
0
0
19
0.00
0.39
0.0
1.4
—
—
—
0
0
0
19
0.00
0.39
0.0
4.8
—
—
—
0
0
87
955
0.91
0.38
3.7
3.7
8.85
7.99
mmol/l
1.39
87
943
254
2670
0.94
0.38
2.2
2.4
9.31
10.80
umol/l
0.36
191
2287
12
89
1.35
0.37
2.5
3.0
—
—
—
0
0
23
278
0.82
0.37
1.2
1.1
—
—
—
0
0
67
599
1.12
0.37
2.9
2.4
2.05
1.95
mg/l
0.35
51
508
10
134
0.74
0.35
1.1
1.2
45.40
75.37
mg/l
—
5
83
30
351
0.85
0.35
1.3
1.2
1.11
0.82
nmol/l
0.34
23
280
15
189
0.79
0.35
1.2
1.3
13.92
10.55
u/l
—
8
144
6
86
0.70
0.33
1.7
2.3
—
—
—
0
0
111
1193
0.93
0.33
5.4
5.3
—
—
—
0
0
17
208
0.81
0.31
1.1
1.1
351.67
337.36
u/ml
0.06
12
112
34
294
1.15
0.31
1.2
1.3
275.48
273.80
mosm/kgh2o
0.15
25
196
92
994
0.92
0.31
3.6
3.6
1.80
1.73
mmol/l
0.35
92
984
359
3447
1.04
0.31
3.9
3.3
277.00
324.80
ng/l
1.25
331
3124
7
54
1.29
0.30
1.4
1.2
—
—
—
0
0
86
790
1.09
0.30
2.5
3.0
7.31
7.53
kpa
0.47
81
721
22
259
0.85
0.29
1.5
1.2
—
—
—
0
0
21
248
0.84
0.28
1.0
1.1
—
—
—
0
0
48
531
0.90
0.27
1.6
2.8
568.21
1148.70
u/ml
0.43
40
478
37
415
0.89
0.27
1.4
1.4
6.50
6.60
mmol/l
0.08
30
381
14
171
0.82
0.26
1.6
3.0
7.48
7.39
mmol/l
—
9
109
401
3877
1.04
0.26
1.8
1.9
—
—
—
0
0
5
72
0.69
0.26
1.0
1.1
—
—
—
0
0
5
73
0.68
0.26
1.0
1.1
—
—
—
0
0
1315
13288
0.98
0.24
5.4
7.2
4.91
4.60
e9/l
2.77
1134
11294
17
201
0.84
0.24
1.1
1.0
—
—
—
0
0
44
398
1.10
0.23
1.3
1.4
—
—
—
0
0
14
115
1.21
0.23
8.7
3.6
55.04
53.76
%
0.07
14
107
16
189
0.84
0.23
1.2
1.5
4.56
5.16
mg/l
0.17
11
178
122
1283
0.95
0.22
1.3
1.4
—
—
—
0
0
0
10
0.00
0.21
0.0
1.7
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
0
12
0.00
0.21
0.0
1.1
—
—
—
0
0
0
12
0.00
0.21
0.0
1.6
—
1.73
—
0
7
0
13
0.00
0.21
0.0
2.0
—
—
—
0
0
0
13
0.00
0.21
0.0
1.8
—
1.27
—
0
13
0
14
0.00
0.20
0.0
1.1
—
—
—
0
0
28
312
0.89
0.20
1.2
1.4
79.82
66.46
%
1.67
17
205
40
364
1.10
0.19
2.7
2.3
2.88
2.32
u/field
0.19
17
98
24
212
1.13
0.19
1.4
1.4
—
—
—
0
0
40
366
1.09
0.18
1.8
1.4
3.28
4.96
iu/l
0.93
11
96
7
61
1.14
0.17
2.3
1.2
—
—
—
0
0
5
67
0.74
0.17
2.0
2.0
—
—
—
0
0
7
86
0.81
0.14
1.3
1.8
—
—
—
0
0
22
243
0.90
0.14
1.0
1.1
32.01
34.06
mmol/l
0.20
16
196
235
2398
0.98
0.12
2.1
2.1
—
—
—
0
0
519
5106
1.02
0.11
2.1
2.4
10.47
11.25
umol/l
1.62
414
4601
5
44
1.13
0.10
1.4
1.6
—
—
—
0
0
10
114
0.87
0.10
1.3
1.3
1.14
0.99
nmol/l
—
5
88
499
5035
0.99
0.09
1.4
1.6
2.01
1.65
mg/l
0.62
357
3938
5
45
1.11
0.09
1.0
1.1
—
—
—
0
0
385
3892
0.98
0.09
3.6
4.4
1.05
1.05
mmol/l
0.08
305
3483
16
175
0.91
0.09
1.3
1.5
10.59
9.69
%
0.34
16
175
5
63
0.79
0.08
1.8
2.4
—
—
—
0
0
6
72
0.83
0.07
4.0
2.1
—
—
—
0
0
8
74
1.08
0.07
2.4
1.8
19.51
36.04
u/l
—
8
68
8
75
1.06
0.07
1.0
1.2
—
—
—
0
0
14
127
1.10
0.07
1.2
1.3
4.59
265.55
ug/l
—
9
66
65
627
1.03
0.07
1.4
1.5
42803.66
20239.15
e6/l
0.72
47
445
76
738
1.03
0.06
1.1
1.2
305.04
219.45
u/ml
0.58
69
655
69
669
1.03
0.06
1.2
1.5
248.19
258.38
ug/g
0.16
37
415
205
2072
0.99
0.06
2.7
3.8
5.15
5.18
kpa
0.16
168
1845
23
242
0.95
0.05
1.6
2.1
491.20
613.24
ml
—
5
136
12
130
0.92
0.05
1.2
1.2
—
—
—
0
0
22
229
0.96
0.03
2.5
3.3
44.21
36.37
mg/l
0.12
17
186
139
1401
0.99
0.03
2.9
2.9
—
—
—
0
0
63
640
0.98
0.03
2.7
2.5
—
—
—
0
0
39
399
0.97
0.03
1.2
1.2
—
—
—
0
0
25
241
1.03
0.02
1.3
1.3
—
—
—
0
0
50
508
0.98
0.02
1.4
1.4
—
—
—
0
0
64
647
0.99
0.01
2.6
2.5
107.13
105.38
mmol/l
1.09
64
641
64
647
0.99
0.01
2.6
2.5
4.15
4.14
mmol/l
0.08
64
641
204
2043
1.00
0.01
2.7
3.8
7.42
7.41
ph
0.52
34
253
15
156
0.96
0.01
2.3
2.4
—
—
—
0
0
14
134
1.04
0.00
1.1
1.4
21.86
18.34
%
0.16
14
117
125
1243
1.00
0.00
1.3
1.4
—
—
—
0
0
10
99
1.01
0.00
1.0
1.1
44.54
39.22
g/l
—
5
43
10
96
1.04
0.00
1.4
2.4
1640.00
1794.79
ml
—
5
71
807
8052
1.00
0.00
3.6
3.5
0.52
0.58
e6/l
0.51
682
6278
69
689
1.00
0.00
1.3
1.3
55.60
59.89
mmol/l
0.52
52
542
33
325
1.01
0.00
1.2
1.3
26.68
11.93
u/l
0.52
25
295
91
907
1.00
0.00
3.0
2.6
—
—
—
0
0
16
161
0.99
0.00
2.0
1.8
—
70.00
—
0
5
18
183
0.98
0.00
1.2
1.2
—
—
—
0
0
31
314
0.98
0.00
2.4
1.8
—
—
—
0
0
35
345
1.01
0.00
7.0
4.2
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
40.67
—
0
6
0
7
0.00
0.00
0.0
2.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.6
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
9
95
0.94
0.00
1.7
1.4
—
10.26
—
0
5
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
6
64
0.93
0.00
1.2
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
254.20
—
0
5
0
7
0.00
0.00
0.0
1.7
—
2.40
—
0
7
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
2.6
—
6.81
—
0
7
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
0.00
0.0
1.4
—
0.80
—
0
5
0
5
0.00
0.00
0.0
2.2
—
—
—
0
0

Mortality – FinRegistry

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

Index endpoint: AD_AM – Alzheimer’s disease (Atypical or mixed)

GWS hits: -

This endpoint is excluded from FinRegistry analyses (omitted endpoint).