Periodontosis

K11_PERIODONTOSIS

No definition available.

Endpoint definition

↥

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps	FinnGen
Phenotype data	520210
1. Apply sex-specific rule None	520210
2. Check conditions None	520210
3. Check pre-conditions, main-only, mode, registry filters Registry filters: Hospital discharge: ICD-10 — K05.4 Hospital discharge: ICD-9 — 5235 Hospital discharge: ICD-8 — 5235 Cause of death: ICD-10 — K05.4 Cause of death: ICD-9 — 5235 Cause of death: ICD-8 — 5235 2 out of 7 registries used, show all original rules.	66
4. Check minimum number of events None	66
5. Include endpoints None	66
6. Filter based on genotype QC (FinnGen only)	66

Control definitions (FinnGen only)

Control exclude: K11_ORAL

Extra metadata

First used in FinnGen datafreeze: DF5

NAME	K11_PERIODONTOSIS
CONTROL_EXCLUDE	K11_ORAL
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX
INCLUDE
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10	K054
HD_ICD_9	5235
HD_ICD_8	5235
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10	K054
COD_ICD_9	5235
COD_ICD_8	5235
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

Similar endpoints

↥

List of similar endpoints to Periodontosis based on the number of shared cases.

Similar with more cases:

Similar with less cases:

None

Case counts by codes

↥

FinnGen case counts by registry codes:

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

Key figures

	All	Female	Male
Number of individuals
Whole population	624	303	307
Only index persons	534	275	259
Unadjusted period prevalence (%)
Whole population	0.01	0.01	0.01
Only index persons	0.01	0.01	0.01
Median age at first event (years)
Whole population	50.80	48.14	53.40
Only index persons	49.52	47.02	52.17

-FinnGen-

Key figures

	All	Female	Male
Number of individuals	66	37	29
Unadjusted period prevalence (%)	0.01	0.01	0.01
Median age at first event (years)	55.77	52.02	60.57

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS (R11)

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log₁₀(p-value) ≥ 6.

Matched cohort

Matched cases
59: Matched controls
589

Code

Vocabulary

Description

Odds Ratio

-log₁₀(p)

N matched cases

N matched controls

K05.4

ICD-10 Finland

Periodontosis

+∞

77.1

K05.31

ICD-10 Finland

Periodontitis pronounced

+∞

22.3

K05.30

ICD-10 Finland

Periodontitis complex

+∞

16.4

K04.5

ICD-10 Finland

Chronic apical periodontitis

13.3

15.8

WZC10

NOMESCO Finland

Extensive specialist consultion with written report

77.8

15.7

EBA10

NOMESCO Finland

Surgical removal of tooth

30.2

14.5

K08.1

ICD-10 Finland

Loss of teeth due to accident, extraction or local periodontal disease

46.6

14.4

EB1HA

NOMESCO Finland

Panorama tomography of teeth and jaws or similar X-ray examination

8.1

12.2

SAA03

NOMESCO Finland

Extended examination of mouth

7.9

11.5

SAA04

NOMESCO Finland

Special inverstigation of mouth

27.1

9.9

SBB10

NOMESCO Finland

Teeth copy

36.8

9.8

K05.10

ICD-10 Finland

Gingivitis (chronic) NOS

+∞

8.5

EBA00

NOMESCO Finland

Extraction of tooth

5.9

8.2

EBA15

NOMESCO Finland

Extraction of large number of teeth

29.5

7.9

WZC00

NOMESCO Finland

Planning of intervention or health care consultation

5.3

7.7

SAA02

NOMESCO Finland

Basic examination of mouth

4.9

7.7

177

SDA04

NOMESCO Finland

Very demanding parodonthologic therapy

6.8

7.6

K05.18

ICD-10 Finland

Chronic gingivitis

+∞

7.4

SBA00

NOMESCO Finland

Microbiological examinations

+∞

7.4

EB1AA

NOMESCO Finland

Tooth X-ray examination

4.6

7.3

157

K02.1

ICD-10 Finland

Caries of dentine

4.6

7.3

158

SXB00

NOMESCO Finland

Removeal of sutres from oral mucosa

16.8

6.7

SDA02

NOMESCO Finland

Parodonthologic therapy

4.9

6.4

SDA12

NOMESCO Finland

Treatment of complicated periodontal disease

+∞

6.4

K05.3

ICD-10 Finland

Chronic periodontitis

+∞

6.4

WX110

NOMESCO Finland

Local anesthesy

4.2

6.1

241

LabWAS

↥

N Cases

N Controls

-log₁₀(p)

cases

controls

cases

controls

unit

-log₁₀(p)

N cases

N controls

(3023368) Bacteria identified in Blood by Culture

122

3.05

4.46

5.4

4.2

—

(36031861) Influenza virus A and B and SARS-CoV-2 (COVID-19) and Respiratory syncytial virus RNA panel - Respiratory system specimen by NAA with probe detection

4.54

3.85

1.8

2.4

—

(3016431) Calcium.ionized [Moles/volume] adjusted to pH 7.4 in Serum or Plasma

217

2.45

3.15

12.2

6.0

1.21

mmol/l

0.08

185

(3042936) Bacteria identified in Isolate by Culture

3.05

3.13

2.0

—

(36304419) Bacteria [Presence] in Urine

121

2.55

3.06

3.7

3.4

—

(3044938) Influenza virus A RNA [Presence] in Specimen by NAA with probe detection

2.83

3.03

2.7

1.9

—

(1761868) Lipid panel - Serum or Plasma

206

0.30

3.02

5.1

2.7

—

(3030467) Casts [#/volume] in Urine by Automated count

125

2.45

2.83

4.3

3.4

0.39

e6/l

0.00

100

(3026008) Bacteria identified in Urine by Culture

133

2.42

2.82

3.4

3.2

—

(40765161) Human bocavirus DNA [Presence] in Specimen by NAA with probe detection

8.88

2.79

1.6

1.7

—

(3042194) Human metapneumovirus RNA [Presence] in Specimen by NAA with probe detection

6.47

2.76

1.5

1.8

—

(3030306) Epithelial cells.non-squamous [#/volume] in Urine by Automated count

2.61

2.72

3.3

2.8

0.46

0.40

e6/l

0.12

(3019250) Coagulation factor VIII activity actual/normal in Platelet poor plasma by Coagulation assay

5.08

2.67

1.9

2.5

167.86

155.60

—

(3022948) Iron [Moles/volume] in Serum or Plasma

2.63

2.65

4.2

1.9

10.46

13.88

umol/l

1.42

(3021347) Calcium.ionized [Moles/volume] in Serum or Plasma

204

2.24

2.59

11.6

5.5

1.21

mmol/l

0.03

193

(3019230) Fractional oxyhemoglobin in Venous blood

7.60

2.59

3.2

3.0

73.60

65.11

—

(3004789) Transferrin [Mass/volume] in Serum or Plasma

2.61

2.52

4.4

1.8

1.93

2.33

g/l

1.91

(3004119) Hemoglobin [Mass/volume] in Venous blood

3.69

2.50

2.8

3.2

125.33

134.44

g/l

—

(3017143) Hepatitis C virus Ab [Presence] in Serum

2.81

2.45

2.8

1.4

—

(46235355) HIV 1 and 2 tests - Meaningful Use set

2.52

2.45

2.4

1.6

—

(3044254) Respiratory syncytial virus RNA [Presence] in Specimen by NAA with probe detection

4.96

2.32

2.3

2.5

—

(3024889) Methemoglobin/Hemoglobin.total in Venous blood

3.64

2.26

3.0

0.57

0.68

—

(42870588) Differential panel, method unspecified - Blood

161

2.15

2.26

11.2

4.2

—

(3029879) Epithelial cells.squamous [#/volume] in Urine by Automated count

2.46

2.25

3.5

2.9

1.11

0.85

e6/l

—

(46236098) ABO and Rh group [Type] in Blood by Confirmatory method

121

2.23

2.24

4.1

2.3

—

(3000991) Gas panel - Venous blood

3.01

2.21

15.8

8.8

—

(3002032) Base excess in Venous blood by calculation

2.80

2.14

7.5

3.4

-1.29

2.39

mmol/l

1.24

(3044640) Blood type and Crossmatch panel - Blood

164

2.09

2.13

3.5

2.2

—

(3024928) Oxygen saturation in Venous blood

5.31

2.11

3.2

3.4

—

(3040853) Adenovirus DNA [Identifier] in Specimen by NAA with probe detection

5.31

2.11

1.6

1.8

—

(3010517) Carboxyhemoglobin/Hemoglobin.total in Venous blood

3.35

2.09

3.0

2.9

1.34

1.65

—

(46235759) Influenza virus B RNA [Presence] in Nasopharynx by NAA with probe detection

4.29

2.09

3.3

2.6

—

(3011960) Natriuretic peptide B [Mass/volume] in Serum or Plasma

3.43

1.94

3.1

2.7

72.86

273.80

ng/l

—

(3016293) Bicarbonate [Moles/volume] in Serum or Plasma

3.11

1.93

5.9

8.4

21.90

25.60

mmol/l

—

(3000515) Antithrombin actual/normal in Platelet poor plasma by Chromogenic method

3.77

1.88

1.7

72.83

89.82

—

(3019309) Folate [Moles/volume] in Red Blood Cells

2.26

1.82

1.4

1.6

1436.38

1233.38

nmol/l

—

(3029287) Urinalysis microscopic panel [#/volume] - Urine by Automated count

164

1.97

1.80

4.2

3.3

—

(3051552) Clostridioides difficile toxin genes [Presence] in Stool by NAA with probe detection

3.14

1.78

2.4

1.7

—

(3001604) Monocytes [#/volume] in Blood

247

1.89

1.72

8.4

5.0

0.64

0.55

e9/l

1.22

212

(3006315) Basophils [#/volume] in Blood

247

1.89

1.72

9.1

5.0

0.04

e9/l

0.07

214

(3013115) Eosinophils [#/volume] in Blood

257

1.88

1.71

11.2

5.3

0.20

0.19

e9/l

0.09

231

(3024135) Streptococcus.beta-hemolytic [Presence] in Throat by Organism specific culture

2.23

1.69

2.0

1.5

—

(3043924) Respiratory syncytial virus RNA [Identifier] in Specimen by NAA with probe detection

2.44

1.68

2.1

1.7

—

(3038288) Influenza virus B RNA [Presence] in Specimen by NAA with probe detection

2.39

1.61

2.3

1.7

—

(3005895) Myoglobin [Mass/volume] in Serum or Plasma

3.51

1.55

1.2

2.6

376.80

412.35

ug/l

—

(40771025) 25-Hydroxyvitamin D3+25-Hydroxyvitamin D2 [Moles/volume] in Serum or Plasma

181

1.83

1.52

2.5

2.0

66.55

75.68

nmol/l

0.96

163

(3019198) Lymphocytes [#/volume] in Blood

255

1.79

1.50

8.2

4.9

2.02

2.08

e9/l

0.09

225

(3009201) Thyrotropin [Units/volume] in Serum or Plasma

464

2.11

1.44

4.3

4.4

1.81

1.90

mu/l

0.20

423

(43054903) Holo-transcobalamin II [Moles/volume] in Serum

184

1.79

1.43

1.9

1.8

101.82

99.06

pmol/l

0.12

106

(3000494) Fungus identified in Specimen by Culture

2.24

1.42

1.6

1.2

—

(3019284) Hepatitis B virus surface Ag [Presence] in Serum

2.10

1.40

2.8

1.6

—

(3022313) Gas panel - Capillary blood

3.09

1.38

3.6

—

(46237023) Hepatitis B virus core and surface Ab and surface Ag panel - Serum

3.09

1.38

3.0

1.4

—

(3002582) Erythrocytes [#/volume] in Urine

142

1.82

1.38

4.7

3.4

17.71

36.03

e6/l

0.33

113

(3001079) Blood group antibody screen [Presence] in Serum or Plasma

241

1.74

1.36

5.0

4.2

—

(3019225) pH of Specimen

2.54

1.34

7.0

4.4

—

(3045783) Sodium and Potassium panel [Moles/volume] - Serum or Plasma

2.23

1.30

7.6

7.9

—

(4035726)

2.25

1.23

1.6

1.3

—

(3014007) Fractional oxyhemoglobin in Arterial blood

2.43

1.21

16.0

9.7

89.42

95.38

—

(3013826) Glucose [Moles/volume] in Serum or Plasma

305

1.68

1.21

9.0

4.0

6.77

6.62

mmol/l

0.13

283

(3027273) Bicarbonate [Moles/volume] in Venous blood

2.62

1.17

3.4

2.8

25.90

25.31

mmol/l

—

(3013650) Neutrophils [#/volume] in Blood by Automated count

297

1.66

1.17

15.3

8.1

4.36

3.96

e9/l

0.59

255

(3052851) Hemolysis interference index of Serum or Plasma

2.49

1.11

2.8

2.6

—

(3011397) Hemoglobin [Presence] in Urine by Test strip

109

1.75

1.07

3.5

3.3

—

(3027238) Thyroperoxidase Ab [Units/volume] in Serum or Plasma

2.18

1.06

1.1

—

230.73

—

(3004716) Salmonella sp identified in Stool by Organism specific culture

2.37

1.05

2.0

1.3

—

(3021879) Hepatitis B virus core Ab [Presence] in Serum

2.12

1.03

2.6

1.5

—

(3018095) Leukocytes [#/volume] in Urine

164

1.62

0.98

5.9

3.7

24.23

61.75

e6/l

0.82

123

(3037467) Urinalysis macro (dipstick) panel - Urine

337

1.57

0.95

5.5

4.0

—

(3028653) Carboxyhemoglobin/Hemoglobin.total in Arterial blood

2.25

0.94

16.0

9.1

2.12

1.47

—

(3006217) Methemoglobin/Hemoglobin.total in Arterial blood

2.17

0.92

16.0

8.9

0.82

0.68

—

(3019902) Methicillin resistant Staphylococcus aureus [Presence] in Specimen by Organism specific culture

1.81

0.80

5.3

2.7

—

(3046870) Tissue transglutaminase IgG Ab [Units/volume] in Serum

2.17

0.76

1.4

1.0

—

(3000492) Spirometry study

1.74

0.71

1.4

1.3

—

(3025941) Bacteria identified in Stool by Culture

1.85

0.67

1.8

1.2

—

(36660697) Celiac disease serology panel - Serum

1.72

0.65

1.1

1.0

—

(3007853) Bacteria identified in Skin by Aerobe culture

1.65

0.63

1.6

1.4

—

(3010156) C reactive protein [Mass/volume] in Serum or Plasma by High sensitivity method

0.00

0.61

0.0

3.1

—

4.36

—

(3029511) Human papilloma virus DNA [Presence] in Specimen by NAA with probe detection

0.00

0.61

0.0

1.3

—

(3021584) Pregnancy associated plasma protein A [Units/volume] in Serum or Plasma

0.00

0.61

0.0

1.5

—

(46236952) Glomerular filtration rate/1.73 sq M.predicted [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (MDRD)

1.73

0.58

2.0

2.3

—

63.31

—

(3021589) Normoblasts [#/volume] in Blood

230

1.38

0.56

12.6

7.6

0.00

e9/l

0.00

186

(40768797) Stomach Pathology biopsy report

1.58

0.53

1.2

1.1

—

(40761535) Cells panel - Urine sediment

1.55

0.53

4.5

2.9

—

(3013512) EKG study

140

1.39

0.49

7.1

3.3

—

(40763086) Leukocyte esterase [Presence] in Urine by Automated test strip

193

0.71

0.48

5.3

3.4

—

(3006923) Alanine aminotransferase [Enzymatic activity/volume] in Serum or Plasma

557

1.56

0.43

15.8

9.3

25.37

25.87

u/l

0.09

540

(3050129) First trimester maternal screen panel - Serum or Plasma

0.00

0.42

0.0

1.3

—

(3017895) Helicobacter pylori Ab [Units/volume] in Serum

0.00

0.41

0.0

1.7

—

(1761482) Bacteria [#/volume] in Urine by Culture

0.00

0.41

0.0

5.1

—

(3039443) Prostate specific Ag panel - Serum or Plasma

0.00

0.41

0.0

2.1

—

(3044889) 12 lead EKG panel

359

1.29

0.40

4.5

3.5

—

(40758558) Short blood count panel - Blood

127

1.34

0.38

13.6

6.5

—

(3016417) Amylase.pancreatic [Enzymatic activity/volume] in Serum or Plasma

1.47

0.37

2.3

3.2

29.83

46.37

u/l

—

(3012516) Albumin [Mass/volume] in Urine

128

1.33

0.36

5.3

2.9

96.91

50.81

mg/l

0.46

(3007164) IgA [Mass/volume] in Serum or Plasma

111

1.33

0.33

1.4

1.2

2.87

2.49

g/l

—

(40760892) CBC W Ordered Manual Differential panel - Blood

108

0.71

0.32

3.4

4.6

—

(3020460) C reactive protein [Mass/volume] in Serum or Plasma

523

1.31

0.27

26.7

12.1

26.84

21.95

mg/l

0.50

409

(3041096) Erythrocytes [Presence] in Urine by Automated

136

0.77

0.26

4.8

3.0

—

(40761536) Microorganisms panel - Urine sediment

1.34

0.24

7.2

3.0

—

(3009542) Hematocrit [Volume Fraction] of Blood

474

1.23

0.23

26.9

13.6

37.69

40.48

1.90

367

(40768804) Tissue Pathology biopsy report

194

1.20

0.22

2.2

1.9

—

(1175715) Chlamydophila pneumoniae IgM Ab [Presence] in Serum by Immunoassay

0.00

0.21

0.0

1.1

—

(3020321) Streptococcus agalactiae [Presence] in Vaginal fluid by Organism specific culture

0.00

0.21

0.0

1.5

—

(3023939) Sjogrens syndrome-A extractable nuclear Ab [Units/volume] in Serum

0.00

0.21

0.0

1.2

—

(40768793) Breast Pathology biopsy report

0.00

0.21

0.0

1.2

—

(3008714) Choriogonadotropin [Multiple of the median] adjusted in Serum or Plasma

0.00

0.21

0.0

1.2

—

(3051387) C reactive protein [Mass/volume] in Capillary blood

0.00

0.21

0.0

2.8

—

24.99

—

(3047352) Trisomy 18 risk [Likelihood] in Fetus

0.00

0.21

0.0

1.2

—

(40763531) Fetal Nuchal fold [Multiple of the median] Thickness adjusted for maternal weight

0.00

0.21

0.0

1.2

—

(3036086) Jo-1 extractable nuclear Ab [Units/volume] in Serum by Immunoassay

0.00

0.21

0.0

1.2

—

(3005033) Fetal Nuchal fold Thickness US

0.00

0.21

0.0

1.2

—

(46235831) Pregnancy associated plasma protein A [Multiple of the median] adjusted in Serum or Plasma

0.00

0.21

0.0

1.2

—

(3049207) Fetal Trisomy 21 risk [Likelihood] Based on maternal age

0.00

0.21

0.0

1.2

—

(3041942) Cyclic citrullinated peptide Ab [Units/volume] in Serum

1.27

0.21

1.2

1.3

1.02

6.88

u/ml

—

(3043238) Trisomy 21 risk [Likelihood] in Fetus

0.00

0.20

0.0

1.2

—

(3019145) Choriogonadotropin.beta subunit free [Mass/volume] in Serum or Plasma

0.00

0.20

0.0

1.4

—

(3003694) ABO and Rh group [Type] in Blood

138

1.21

0.20

1.7

1.3

—

(3003396) Base excess in Arterial blood by calculation

1.25

0.19

13.3

7.6

-2.26

1.92

mmol/l

—

(3048689) Calprotectin [Mass/mass] in Stool

1.19

0.18

3.1

1.7

152.86

100.36

ug/g

—

(3020564) Creatinine [Moles/volume] in Serum or Plasma

557

1.17

0.07

29.2

14.3

94.40

77.66

umol/l

1.02

557

(3013603) Prostate specific Ag [Mass/volume] in Serum or Plasma

169

1.09

0.05

5.4

4.3

2.50

1.80

ug/l

0.58

148

(40761511) CBC panel - Blood by Automated count

551

1.11

0.04

16.7

11.2

—

(40764999) Glomerular filtration rate/1.73 sq M.predicted [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (CKD-EPI)

492

1.07

0.02

24.1

11.4

75.28

81.18

ml/min/173m2

0.54

408

(3001784) Prostate Specific Ag Free/Prostate specific Ag.total in Serum or Plasma

133

1.07

0.02

3.9

4.0

31.07

20.34

—

(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection

334

1.04

0.00

4.1

3.1

—

(3018251) Fasting glucose [Moles/volume] in Serum or Plasma

497

1.02

0.00

5.0

4.2

5.81

5.89

mmol/l

0.16

462

(3051611) Lipemic interference index of Serum or Plasma

0.00

0.0

2.4

—

(3044290) Cell count panel - Cerebral spinal fluid

0.00

0.0

1.0

—

(3005570) Glucose [Moles/volume] in Urine

0.00

0.0

4.2

—

(3000093) Morphology [Interpretation] in Blood Narrative

0.00

0.0

1.0

—

(4027681)

0.00

0.0

1.2

—

(3005791) Eosinophil cationic protein (ECP) [Mass/volume] in Serum

0.00

0.0

2.2

—

15.72

—

(3029080) Hemoglobin [Entitic mass] in Reticulocytes

0.00

0.0

2.2

—

32.40

—

(43055089) Myosin Ab [Presence] in Serum or Plasma by Immunoblot

0.00

0.0

1.0

—

(3017315) Amylase [Enzymatic activity/volume] in Urine

0.00

0.0

1.0

—

228.80

—

(40762119) U1 small nuclear ribonucleoprotein 70kD Ab [Units/volume] in Serum

0.00

0.0

1.0

—

(3004451) EKG impression Narrative

0.00

0.0

1.4

—

(3018387) Mycoplasma pneumoniae IgG Ab [Units/volume] in Serum

0.00

0.0

1.2

—

(3014702) Chromogranin A [Moles/volume] in Serum or Plasma

0.00

0.0

3.8

—

1.16

—

(3000855) Microscopic observation [Identifier] in Vaginal fluid by Gram stain

0.00

0.0

1.2

—

(1001926) Buprenorphine [Presence] in Urine by Screen method

0.00

0.0

1.1

—

(3038177) Helicobacter pylori Ab [Presence] in Serum

0.00

0.0

1.5

—

(42868544) Hantavirus puumala IgM Ab [Presence] in Serum or Plasma by Immunofluorescence

0.00

0.0

1.1

—

(3047007) Chlamydophila sp Ab [Presence] in Serum

0.00

0.0

1.0

—

(40760888) Immunoglobulin light chains.free panel - Serum

0.00

0.0

4.6

—

(3025130) Human papilloma virus identified in Specimen

0.00

0.0

1.5

—

(3004616) Nuclear Ab [Presence] in Serum

0.00

0.0

1.1

—

(3043405) Microscopic observation [Identifier] in Specimen by Non-gynecological cytology method

0.00

0.0

1.0

—

(3026515) Parvovirus B19 IgM Ab [Units/volume] in Serum

0.00

0.0

1.2

—

(3023419) Bacteria identified in Sputum by Culture

0.00

0.0

3.7

—

(21492888) Glucose tolerance 2 hours gestational panel - Serum or Plasma

0.00

0.0

1.7

—

(3008364) Apolipoprotein A-I [Mass/volume] in Serum or Plasma

0.00

0.0

1.6

—

(3009550) Parvovirus B19 IgG Ab [Titer] in Serum

0.00

0.0

1.2

—

(1002102) Choriogonadotropin.intact+Beta subunit [Mass/volume] in Serum or Plasma

0.00

0.0

1.7

—

(3004915) Chlamydophila pneumoniae IgA Ab [Units/volume] in Serum

0.00

0.0

1.0

—

(3011831) Apolipoprotein B/Apolipoprotein A-I [Percentile]

0.00

0.0

1.6

—

(3014051) Protein [Presence] in Urine by Test strip

0.00

0.0

2.4

—

(43054914) Glucose tolerance 2 hours panel - Serum or Plasma

1.02

0.00

1.7

1.8

—

(3036535) Thyroglobulin [Mass/volume] in Serum or Plasma

0.00

0.0

5.3

—

Mortality – FinRegistry

↥

Association

Association between endpoint K11_PERIODONTOSIS and mortality.

Females

No data

Males

Parameter	HR [95% CI]	p-value
K11_PERIODONTOSIS	2.631 [1.8, 3.85]	< 0.001
Birth year	0.989 [0.98, 1.0]	0.072

During the follow-up period (1.1.1998 — 31.12.2019), 77 out of 239 males with K11_PERIODONTOSIS died.

Mortality risk

Mortality risk for people of age

years, who have K11_PERIODONTOSIS.

N-year risk	Females	Males
1	No data	0.494%
5	No data	2.946%
10	No data	7.188%
15	No data	14.082%
20	No data	22.837%

Relationships between endpoints

↥

Index endpoint: K11_PERIODONTOSIS – Periodontosis

GWS hits: -

Endpoint

Case Overlap

Survival Analysis

Genetic Correlations

Genetic Signals

N (Jaccard index)

HR [CI]

rg [CI]

Hits

Coloc Hits

FinRegistry

FinnGen

FinRegistry

FinnGen

Loading data

Periodontosis

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

1. Apply sex-specific rule

2. Check conditions

3. Check pre-conditions, main-only, mode, registry filters

4. Check minimum number of events

5. Include endpoints

6. Filter based on genotype QC (FinnGen only)

Similar endpoints

Case counts by codes

Summary Statistics

-FinRegistry-

Key figures

-FinnGen-

Key figures

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS (R11)

Matched cohort

LabWAS

Mortality – FinRegistry

Association

Females

Males

Mortality risk

Relationships between endpoints