Drug-induced fever

DRUGADVERS_FEVER

No definition available.

Endpoint definition

↥

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps	FinnGen
Phenotype data	519972
1. Apply sex-specific rule None	519972
2. Check conditions None	519972
3. Check pre-conditions, main-only, mode, registry filters Registry filters: Hospital discharge: ICD-10 — R50.2# 1 out of 7 registries used, show all original rules.	62
4. Check minimum number of events None	62
5. Include endpoints None	62
6. Filter based on genotype QC (FinnGen only)	62

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy: C
First used in FinnGen datafreeze: DF5

NAME	DRUGADVERS_FEVER
CONTROL_EXCLUDE
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX
INCLUDE
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10	R502
HD_ICD_9
HD_ICD_8
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10
COD_ICD_9
COD_ICD_8
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

Similar endpoints

↥

List of similar endpoints to Drug-induced fever based on the number of shared cases.

Similar with more cases:

Similar with less cases:

None

Case counts by codes

↥

FinnGen case counts by registry codes:

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

	All	Female	Male
Number of individuals	62	36	26
Unadjusted period prevalence (%)	0.01	0.01	0.01
Median age at first event (years)	62.62	62.82	62.33

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log₁₀(p-value) ≥ 6.

Matched cohort

Matched cases
62: Matched controls
620

Code

Vocabulary

Description

Odds Ratio

-log₁₀(p)

N matched cases

N matched controls

R50.2

ICD-10 Finland

Drug-induced fever

+∞

89.0

R50.9

ICD-10 Finland

Fever, unspecified

10.2

19.4

GD1AA

NOMESCO Finland

Thorax X-ray examination

5.2

8.4

210

WZC00

NOMESCO Finland

Treatment plan or consultation

4.3

7.4

152

A49.9

ICD-10 Finland

Bacterial infection, unspecified

5.5

7.3

A03FA01

ATC

metoclopramide; systemic, rectal

3.9

6.3

LabWAS

↥

N Cases

N Controls

-log₁₀(p)

cases

controls

cases

controls

unit

-log₁₀(p)

N cases

N controls

(3023368) Bacteria identified in Blood by Culture

139

6.29

11.69

7.1

4.3

—

(3044938) Influenza virus A RNA [Presence] in Specimen by NAA with probe detection

5.05

8.88

2.6

1.9

—

(3043924) Respiratory syncytial virus RNA [Identifier] in Specimen by NAA with probe detection

4.78

7.40

2.1

1.8

—

(3038288) Influenza virus B RNA [Presence] in Specimen by NAA with probe detection

4.45

6.59

2.2

1.9

—

(40760892) CBC W Ordered Manual Differential panel - Blood

263

3.59

5.00

10.8

6.2

—

(3042194) Human metapneumovirus RNA [Presence] in Specimen by NAA with probe detection

7.88

4.33

1.4

1.7

—

(3019198) Lymphocytes [#/volume] in Blood

289

3.29

4.21

10.5

5.6

1.93

1.88

e9/l

0.13

257

(3026008) Bacteria identified in Urine by Culture

165

2.94

4.19

3.8

3.0

—

(3006262) Parainfluenza virus 3 RNA [Presence] in Specimen by NAA with probe detection

10.88

3.57

1.0

1.8

—

(3012158) Parainfluenza virus 2 RNA [Presence] in Specimen by NAA with probe detection

10.88

3.57

1.0

1.8

—

(3013650) Neutrophils [#/volume] in Blood by Automated count

328

3.05

3.44

21.4

10.3

3.88

4.03

e9/l

0.20

284

(3011960) Natriuretic peptide B [Mass/volume] in Serum or Plasma

3.84

3.40

4.4

2.3

145.92

151.51

ng/l

0.04

(3016431) Calcium.ionized [Moles/volume] adjusted to pH 7.4 in Serum or Plasma

271

2.70

3.31

10.5

7.9

1.22

mmol/l

0.19

233

(3030905) Polymorphonuclear cells [#/volume] in Blood

8.14

3.13

3.8

1.8

3.48

5.99

e9/l

—

(3032035) Polymorphonuclear cells/100 leukocytes in Blood

8.14

3.13

4.5

1.8

51.33

63.63

—

(3016771) Amylase [Enzymatic activity/volume] in Serum or Plasma

178

2.48

3.05

3.6

2.5

53.81

82.31

u/l

0.57

165

(3022217) INR in Platelet poor plasma by Coagulation assay

250

2.51

3.01

23.3

11.2

1.58

1.27

inr

0.75

(3040853) Adenovirus DNA [Identifier] in Specimen by NAA with probe detection

5.91

2.96

1.6

1.7

—

(3051714) Fibrin D-dimer FEU [Mass/volume] in Platelet poor plasma

118

2.51

2.84

2.0

1.7

0.95

1.05

mg/l

0.11

(3017181) Myelocytes/100 leukocytes in Blood

3.09

2.83

6.2

3.5

1.25

0.74

—

(3002179) Metamyelocytes/100 leukocytes in Blood

3.22

2.83

5.9

3.3

0.71

0.92

—

(3025159) Blasts/100 leukocytes in Blood

3.14

2.73

6.2

3.7

0.00

0.07

—

(3021440) Promyelocytes/100 leukocytes in Blood

3.14

2.73

6.5

3.7

0.29

0.21

—

(40762366) Oxygen capacity [Volume Fraction] in Arterial blood

4.03

2.70

10.0

7.6

—

(3001079) Blood group antibody screen [Presence] in Serum or Plasma

231

2.33

2.66

3.0

2.6

—

(3018095) Leukocytes [#/volume] in Urine

197

2.29

2.59

5.6

3.4

15.31

48.47

e6/l

0.84

142

(3031040) Bacteria [#/volume] in Urine by Automated count

364

2.65

2.55

7.2

4.2

—

48.00

—

(3035995) Alkaline phosphatase [Enzymatic activity/volume] in Serum or Plasma

429

3.00

2.52

16.7

7.6

87.44

83.92

u/l

0.30

401

(3018418) pH of Serum or Plasma

165

2.27

2.49

6.2

5.0

7.40

7.41

—

(3043109) Cytology report of Tissue fine needle aspirate Cyto stain

5.40

2.46

1.2

—

(36304419) Bacteria [Presence] in Urine

158

2.26

2.43

5.3

2.7

—

(42529200) Cancer Ag 15-3 [Units/volume] in Serum or Plasma by Immunoassay

6.67

2.41

8.8

6.4

42.04

140.38

u/ml

—

(3012477) Bordetella pertussis DNA [Presence] in Specimen by NAA with probe detection

6.67

2.41

1.6

1.9

—

(3022806) Fractional oxyhemoglobin in Capillary blood

6.67

2.41

1.8

2.8

90.84

89.34

—

(3029287) Urinalysis microscopic panel [#/volume] - Urine by Automated count

195

2.18

2.31

5.5

2.9

—

(3020891) Body temperature

3.67

2.27

5.5

4.4

—

(3014576) Chloride [Moles/volume] in Serum or Plasma

2.58

2.21

8.6

7.1

102.93

103.90

mmol/l

0.45

(586526) SARS-CoV-2 (COVID-19) RNA [Presence] in Nasopharynx by NAA with probe detection

3.52

2.18

2.0

1.4

—

(40760888) Immunoglobulin light chains.free panel - Serum

5.33

2.11

13.2

4.5

—

(3002482) Mycoplasma pneumoniae DNA [Presence] in Specimen by NAA with probe detection

5.33

2.11

1.6

1.8

—

(3007853) Bacteria identified in Skin by Aerobe culture

2.62

2.02

1.3

1.5

—

(3014007) Fractional oxyhemoglobin in Arterial blood

3.25

2.01

6.1

8.0

94.90

94.26

—

(3004588) Protein electrophoresis panel - Serum or Plasma

2.83

1.89

7.1

3.1

—

(3015635) Cytomegalovirus IgM Ab [Units/volume] in Serum or Plasma

4.43

1.86

1.0

1.3

—

(3013290) Carbon dioxide [Partial pressure] in Blood

4.43

1.86

3.8

4.8

4.42

4.80

kpa

—

(3027315) Oxygen [Partial pressure] in Blood

4.43

1.86

3.8

4.8

8.58

8.17

kpa

—

(3021337) Troponin I.cardiac [Mass/volume] in Serum or Plasma

107

2.12

1.81

6.5

3.1

358.36

90.22

ng/l

0.56

(3014162) Mycobacterium tuberculosis DNA [Presence] in Specimen by NAA with probe detection

3.57

1.79

3.2

2.4

—

(3048929) Epstein Barr virus Ab [Presence] in Serum

3.57

1.79

1.3

1.6

—

(3019060) Gas panel - Arterial blood

2.78

1.76

6.7

4.8

—

(3021879) Hepatitis B virus core Ab [Presence] in Serum

2.51

1.75

1.5

1.6

—

(3017918) Cytomegalovirus IgG Ab [Titer] in Serum or Plasma

4.08

1.75

1.0

1.3

—

(4200892) Spirometry reversibility

2.81

1.73

1.6

1.3

—

(3020779) Urea [Moles/volume] in Serum or Plasma

2.64

1.71

5.2

8.0

7.97

8.78

mmol/l

—

(3000991) Gas panel - Venous blood

2.51

1.65

6.8

—

(37019628) Gastrointestinal bacterial pathogens panel - Stool by NAA with probe detection

3.78

1.65

1.0

1.1

—

(3024135) Streptococcus.beta-hemolytic [Presence] in Throat by Organism specific culture

104

2.03

1.59

1.8

1.5

—

(3017766) Complement C4 [Mass/volume] in Serum or Plasma

3.53

1.55

1.0

1.1

0.24

0.28

g/l

—

(3000620) Complement C3 [Mass/volume] in Serum or Plasma

3.53

1.55

1.0

1.1

1.13

1.32

g/l

—

(40768443) Skin Pathology biopsy report

3.05

1.54

1.2

1.4

—

(3051552) Clostridioides difficile toxin genes [Presence] in Stool by NAA with probe detection

2.60

1.53

1.1

1.5

—

(3007220) Creatine kinase [Enzymatic activity/volume] in Serum or Plasma

156

1.88

1.51

5.3

2.0

144.08

115.19

u/l

0.39

148

(36031861) Influenza virus A and B and SARS-CoV-2 (COVID-19) and Respiratory syncytial virus RNA panel - Respiratory system specimen by NAA with probe detection

2.69

1.50

2.3

1.6

—

(3008909) Norovirus RNA [Presence] in Stool by NAA with probe detection

3.30

1.46

1.2

1.1

—

(3042936) Bacteria identified in Isolate by Culture

2.09

1.44

1.7

2.1

—

(3016293) Bicarbonate [Moles/volume] in Serum or Plasma

2.33

1.41

6.0

7.0

25.17

24.89

mmol/l

—

(46235759) Influenza virus B RNA [Presence] in Nasopharynx by NAA with probe detection

3.10

1.38

3.4

2.2

—

(3044254) Respiratory syncytial virus RNA [Presence] in Specimen by NAA with probe detection

3.10

1.38

3.2

2.2

—

(3037467) Urinalysis macro (dipstick) panel - Urine

376

1.87

1.30

6.4

4.0

—

(3001308) Cholesterol in LDL [Moles/volume] in Serum or Plasma

530

0.53

1.17

5.1

4.9

2.83

2.72

mmol/l

0.35

483

(3019900) Cholesterol [Moles/volume] in Serum or Plasma

521

0.55

1.14

5.0

4.5

4.71

4.61

mmol/l

0.27

478

(3019284) Hepatitis B virus surface Ag [Presence] in Serum

1.86

1.09

1.6

1.5

—

(3016417) Amylase.pancreatic [Enzymatic activity/volume] in Serum or Plasma

2.02

1.06

2.2

2.7

40.78

29.58

u/l

—

(3035350) Ketones [Presence] in Urine by Test strip

275

1.63

1.04

5.7

3.7

0.00

estimate

—

(46235355) HIV 1 and 2 tests - Meaningful Use set

102

1.77

1.03

1.5

1.8

—

(3023602) Cholesterol in HDL [Moles/volume] in Serum or Plasma

517

0.57

1.00

4.7

4.4

1.35

1.47

mmol/l

1.15

469

(3017143) Hepatitis C virus Ab [Presence] in Serum

1.82

0.97

1.7

1.6

—

(3044889) 12 lead EKG panel

380

1.67

0.97

6.0

3.5

—

(3000494) Fungus identified in Specimen by Culture

1.86

0.97

1.3

—

(3028653) Carboxyhemoglobin/Hemoglobin.total in Arterial blood

2.26

0.94

7.8

7.6

1.57

1.42

—

(3006217) Methemoglobin/Hemoglobin.total in Arterial blood

2.26

0.94

7.8

7.6

0.70

0.75

—

(3022948) Iron [Moles/volume] in Serum or Plasma

1.79

0.93

2.2

2.3

11.49

13.28

umol/l

0.25

(40761536) Microorganisms panel - Urine sediment

2.04

0.93

5.0

3.8

—

(3019902) Methicillin resistant Staphylococcus aureus [Presence] in Specimen by Organism specific culture

1.99

0.91

10.6

4.7

—

(3002256) Pathology report gross observation

1.84

0.89

1.7

1.2

—

(3029937) Albumin [Presence] in Urine by Test strip

151

1.59

0.87

7.0

4.0

0.00

estimate

—

(3026989) Triiodothyronine (T3) Free [Moles/volume] in Serum or Plasma

1.90

0.81

1.8

3.3

4.57

4.56

pmol/l

—

(3021601) Nitrite [Presence] in Urine by Test strip

276

1.51

0.81

7.2

5.0

0.00

estimate

—

(3009261) Glucose [Presence] in Urine by Test strip

277

1.50

0.79

5.9

3.7

0.00

estimate

—

(3004789) Transferrin [Mass/volume] in Serum or Plasma

1.72

0.78

2.3

2.2

2.29

2.34

g/l

0.09

(3023024) Carbon dioxide [Partial pressure] in Capillary blood

1.95

0.76

4.4

4.1

4.41

5.05

kpa

—

(3018405) Lactate [Moles/volume] in Arterial blood

2.17

0.76

3.4

6.7

1.18

1.28

mmol/l

—

(3008898) HLA-B27 [Presence]

2.17

0.76

1.2

1.0

—

(46236098) ABO and Rh group [Type] in Blood by Confirmatory method

111

1.59

0.75

2.4

2.3

—

(3028626) Oxygen [Partial pressure] in Capillary blood

2.08

0.74

4.2

5.0

9.14

8.96

kpa

—

(3024889) Methemoglobin/Hemoglobin.total in Venous blood

2.08

0.74

6.4

2.6

0.48

0.82

—

(3019050) Tissue transglutaminase IgA Ab [Units/volume] in Serum

128

0.57

0.74

1.0

1.2

—

0.69

—

(3007164) IgA [Mass/volume] in Serum or Plasma

112

1.58

0.73

5.2

1.4

1.93

2.14

g/l

—

(3048773) Triglyceride [Moles/volume] in Serum or Plasma --fasting

499

0.64

0.72

4.3

3.9

1.42

1.26

mmol/l

0.87

449

(3022313) Gas panel - Capillary blood

2.00

0.72

4.6

4.1

—

(40763086) Leukocyte esterase [Presence] in Urine by Automated test strip

215

1.45

0.68

6.5

3.9

—

(3030981) Hyaline casts [#/volume] in Urine by Automated count

1.85

0.67

3.2

2.5

0.05

0.03

e6/l

—

(3019800) Troponin T.cardiac [Mass/volume] in Serum or Plasma

207

1.44

0.65

5.2

3.4

24.11

29.87

ng/l

0.36

136

(4035726) Immunohistochemistry procedure

1.69

0.64

1.5

1.3

—

(3021589) Normoblasts [#/volume] in Blood

260

1.38

0.56

23.0

9.8

0.00

e9/l

0.50

211

(3019832) Treponema pallidum Ab [Presence] in Serum

1.55

0.53

1.2

1.7

—

(3012516) Albumin [Mass/volume] in Urine

139

1.42

0.51

1.7

3.0

86.79

616.56

mg/l

—

(43054914) Glucose tolerance 2 hours panel - Serum or Plasma

1.55

0.49

1.0

1.5

—

(3011397) Hemoglobin [Presence] in Urine by Test strip

124

1.39

0.44

6.3

3.7

—

(1761482) Bacteria [#/volume] in Urine by Culture

0.00

0.41

0.0

4.5

—

(3041942) Cyclic citrullinated peptide Ab [Units/volume] in Serum

1.38

0.35

1.2

1.3

51.83

9.44

u/ml

—

(3000492) Spirometry study

1.34

0.34

1.8

1.3

—

(3033319) Streptococcus pyogenes Ag [Presence] in Throat

1.33

0.32

1.3

1.5

—

(40758558) Short blood count panel - Blood

150

1.28

0.31

12.4

7.0

—

(3020682) Albumin/Creatinine [Ratio] in Urine

150

1.28

0.31

2.0

3.4

7.74

9.71

mg/mmol

0.15

(40768797) Stomach Pathology biopsy report

1.29

0.29

1.1

1.3

—

(3044640) Blood type and Crossmatch panel - Blood

161

1.26

0.29

2.8

2.3

—

(3045783) Sodium and Potassium panel [Moles/volume] - Serum or Plasma

1.24

0.28

10.1

6.6

—

(40761535) Cells panel - Urine sediment

1.24

0.22

4.4

3.7

—

(36660697) Celiac disease serology panel - Serum

1.21

0.22

1.2

—

(3008037) Lactate [Moles/volume] in Venous blood

0.00

0.21

0.0

3.0

—

1.13

—

(3051387) C reactive protein [Mass/volume] in Capillary blood

0.00

0.21

0.0

5.5

—

24.93

—

(3015816) F5 gene p.Arg506Gln [Presence] in Blood or Tissue by Molecular genetics method

0.00

0.21

0.0

1.0

—

(3021584) Pregnancy associated plasma protein A [Units/volume] in Serum or Plasma

0.00

0.21

0.0

1.5

—

(3038515) Glucose [Moles/volume] in Venous blood

0.00

0.21

0.0

3.0

—

6.42

—

(3027544) Mycobacterium sp identified in Sputum by Organism specific culture

0.00

0.21

0.0

2.9

—

(3029511) Human papilloma virus DNA [Presence] in Specimen by NAA with probe detection

0.00

0.21

0.0

1.6

—

(3018387) Mycoplasma pneumoniae IgG Ab [Units/volume] in Serum

0.00

0.21

0.0

1.0

—

(3002523) Influenza virus A Ag [Presence] in Specimen

0.00

0.21

0.0

1.1

—

(3003740) Influenza virus B Ag [Presence] in Specimen

0.00

0.21

0.0

1.1

—

(3009041) Cardiolipin IgG Ab [Units/volume] in Serum by Immunoassay

0.00

0.21

0.0

1.2

—

6.83

—

(3009201) Thyrotropin [Units/volume] in Serum or Plasma

489

1.24

0.19

5.7

4.7

1.86

1.82

mu/l

0.12

446

(1761868) Lipid panel - Serum or Plasma

174

0.89

0.09

3.0

2.8

—

(3018006) Microscopic observation [Identifier] in Cervix by Cyto stain.thin prep

0.79

0.08

1.3

1.4

—

(3001784) Prostate Specific Ag Free/Prostate specific Ag.total in Serum or Plasma

121

1.09

0.04

4.0

15.45

23.28

—

(3003694) ABO and Rh group [Type] in Blood

147

0.94

0.02

1.4

1.3

—

(43054903) Holo-transcobalamin II [Moles/volume] in Serum

196

0.96

0.00

2.7

1.9

91.12

94.81

pmol/l

0.20

(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection

354

0.97

0.00

4.7

3.0

—

(40768804) Tissue Pathology biopsy report

206

1.03

0.00

2.7

2.1

—

(3013512) EKG study

158

1.02

0.00

4.4

3.6

—

(3041096) Erythrocytes [Presence] in Urine by Automated

158

1.02

0.00

5.6

3.3

—

(3022145) Colonoscopy Study observation

1.02

0.00

1.2

—

(3003510) Neisseria gonorrhoeae DNA [Presence] in Urine by NAA with probe detection

1.02

0.00

1.7

—

(21492711) Cytomegalovirus IgG Ab avidity [Presence] in Serum or Plasma by Immunoassay

0.00

-0.00

0.0

1.1

—

(21494670) JAK2 gene exon 14 targeted mutation analysis in Blood or Tissue by Molecular genetics method

0.00

-0.00

0.0

1.0

—

(40761511) CBC panel - Blood by Automated count

554

1.11

-0.00

31.1

13.1

—

(3020564) Creatinine [Moles/volume] in Serum or Plasma

566

1.09

-0.00

35.7

15.6

70.61

76.67

umol/l

1.41

566

(3019539) Treponema pallidum Ab [Titer] in Serum by Hemagglutination

0.00

-0.00

0.0

2.3

—

(3018301) Testosterone Free [Moles/volume] in Serum or Plasma

0.00

-0.00

0.0

1.2

—

182.16

—

(40763082) Lactate dehydrogenase [Enzymatic activity/volume] in Pleural fluid by Lactate to pyruvate reaction

0.00

-0.00

0.0

1.4

—

161.40

—

(3053028) Streptococcus sp identified in Specimen by Organism specific culture

0.00

-0.00

0.0

1.0

—

(3033705) Calcium.ionized [Moles/volume] in Venous blood

0.00

-0.00

0.0

2.4

—

(4281824) Cell count and differential, peritoneal fluid

0.00

-0.00

0.0

1.0

—

(46235689) Lupus anticoagulant aPTT, dRVVT and PT screening panel W Reflex

0.00

-0.00

0.0

2.0

—

(3025018) Bordetella pertussis Ab [Titer] in Serum

0.00

-0.00

0.0

1.2

—

(21494434) Karyotype in Bone marrow

0.00

-0.00

0.0

1.0

—

(40768806) Pleura Pathology biopsy report

0.00

-0.00

0.0

1.3

—

(3039443) Prostate specific Ag panel - Serum or Plasma

0.00

-0.00

0.0

1.3

—

(44816844) Macroprolactin [Units/volume] in Serum or Plasma

0.00

-0.00

0.0

1.2

—

(36033641) SARS-CoV-2 (COVID-19) Ag [Presence] in Upper respiratory specimen by Rapid immunoassay

0.00

-0.00

0.0

1.1

—

(3004915) Chlamydophila pneumoniae IgA Ab [Units/volume] in Serum

0.00

-0.00

0.0

1.0

—

(3024950) Chlamydia trachomatis DNA [Presence] in Urine by NAA with probe detection

0.91

-0.00

1.8

1.9

—

(3049506) Microalbumin [Mass/time] in Urine collected for unspecified duration

0.00

-0.00

0.0

1.4

—

(3050129) First trimester maternal screen panel - Serum or Plasma

0.00

-0.00

0.0

1.0

—

(3044242) Glucose [Moles/volume] in Arterial blood

0.00

-0.00

0.0

15.0

—

(3041354) Potassium [Moles/volume] in Venous blood

0.00

-0.00

0.0

2.4

—

3.88

—

(3014973) Borrelia burgdorferi IgM Ab [Units/volume] in Cerebral spinal fluid

0.00

-0.00

0.0

1.0

—

(3019225) pH of Specimen

0.94

-0.00

8.2

3.5

—

(3005570) Glucose [Moles/volume] in Urine

0.00

-0.00

0.0

2.7

—

(3027901) Hemoglobin [Mass/volume] in Arterial cord blood

0.00

-0.00

0.0

1.0

—

174.60

—

(3000093) Morphology [Interpretation] in Blood Narrative

0.00

-0.00

0.0

1.4

—

(3049539) Genetic diseases [Identifier] in Blood or Tissue by FISH Nominal

0.00

-0.00

0.0

1.0

—

(3045788) Cell count panel - Pleural fluid

0.00

-0.00

0.0

1.2

—

(3035933) Granulocytes/100 leukocytes in Blood

0.00

-0.00

0.0

1.2

—

(42870365) C reactive protein [Mass/volume] in Blood by High sensitivity method

0.00

-0.00

0.0

2.5

—

(3029634) Reagin Ab [Titer] in Serum by VDRL

0.00

-0.00

0.0

2.3

—

(3035320) C reactive protein [Mass/volume] in Body fluid

0.00

-0.00

0.0

2.2

—

(3035285) Chloride [Moles/volume] in Venous blood

0.00

-0.00

0.0

2.4

—

110.22

—

(40768441) Liver Pathology biopsy report

0.00

-0.00

0.0

1.0

—

(40762485) Glomerular basement membrane Ab [Units/volume] in Serum by Immunoassay

0.00

-0.00

0.0

1.1

—

(3017569) Oxygen content in Arterial blood

0.00

-0.00

0.0

15.2

—

(3017817) Protein [Mass] in Urine collected for unspecified duration

0.00

-0.00

0.0

6.0

—

(3000855) Microscopic observation [Identifier] in Vaginal fluid by Gram stain

0.00

-0.00

0.0

1.7

—

(3019145) Choriogonadotropin.beta subunit free [Mass/volume] in Serum or Plasma

0.00

-0.00

0.0

1.6

—

(21492888) Glucose tolerance 2 hours gestational panel - Serum or Plasma

0.00

-0.00

0.0

2.0

—

Mortality – FinRegistry

↥

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

↥

Index endpoint: DRUGADVERS_FEVER – Drug-induced fever

GWS hits: -

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

≡ Risteys

R13

FinnGen R12 + FinRegistry

FinnGen R11 + FinRegistry

FinnGen R10 + FinRegistry

FinnGen R10

FinnGen R9

FinnGen R8

FinnGen R7

FinnGen R6

FinnGen R5

FinnGen R4

FinnGen R3

Drug-induced fever

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

1. Apply sex-specific rule

2. Check conditions

3. Check pre-conditions, main-only, mode, registry filters

4. Check minimum number of events

5. Include endpoints

6. Filter based on genotype QC (FinnGen only)

All original rules

Similar endpoints

Case counts by codes

Upset plot

Case counts by code for Drug-induced fever (DRUGADVERS_FEVER)

Summary Statistics

-FinRegistry-

-FinnGen-

Key figures

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

CodeWAS

Matched cohort

LabWAS

Mortality – FinRegistry

Relationships between endpoints