Drug-induced fever

DRUGADVERS_FEVER

No definition available.

Endpoint definition

↥

Endpoint definition steps	FinnGen
Phenotype data	520210
1. Apply sex-specific rule None	520210
2. Check conditions None	520210
3. Check pre-conditions, main-only, mode, registry filters Registry filters: Hospital discharge: ICD-10 — R50.2# 1 out of 7 registries used, show all original rules.	58
4. Check minimum number of events None	58
5. Include endpoints None	58
6. Filter based on genotype QC (FinnGen only)	58

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy: C
First used in FinnGen datafreeze: DF5

NAME	DRUGADVERS_FEVER
CONTROL_EXCLUDE
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX
INCLUDE
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10	R502
HD_ICD_9
HD_ICD_8
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10
COD_ICD_9
COD_ICD_8
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

Similar endpoints

↥

List of similar endpoints to Drug-induced fever based on the number of shared cases.

Similar with more cases:

Similar with less cases:

None

Case counts by codes

↥

FinnGen case counts by registry codes:

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

	All	Female	Male
Number of individuals	58	34	24
Unadjusted period prevalence (%)	0.01	0.01	0.01
Median age at first event (years)	62.62	62.82	62.33

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS (R11)

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log₁₀(p-value) ≥ 6.

Matched cohort

Matched cases
52: Matched controls
520

Code

Vocabulary

Description

Odds Ratio

-log₁₀(p)

N matched cases

N matched controls

R50.2

ICD-10 Finland

Drug-induced fever

+∞

74.4

R50.9

ICD-10 Finland

Fever, unspecified

16.3

16.2

A03FA01

ATC

metoclopramide; systemic, rectal

5.8

7.2

A49.9

ICD-10 Finland

Bacterial infection, unspecified

10.2

7.2

GD1AA

NOMESCO Finland

Thorax X-ray examination

4.9

6.8

164

GD1UA

NOMESCO Finland

Thorax X-ray examination outside radiological department

6.7

6.8

J18.9

ICD-10 Finland

Pneumonia, unspecified

5.8

6.6

H02AB06

ATC

prednisolone; systemic

4.5

6.4

162

FM1EE

NOMESCO Finland

Extensive structural and functional ultrasound examination of heart

5.0

6.3

N02AA05

ATC

oxycodone; systemic

6.3

6.2

LabWAS

↥

(ID) Name

N Cases

N Controls

-log₁₀(p)

cases

controls

cases

controls

unit

-log₁₀(p)

N cases

N controls

(3023368) Bacteria identified in Blood by Culture

132

6.45

11.18

7.3

4.0

—

(3044938) Influenza virus A RNA [Presence] in Specimen by NAA with probe detection

4.93

8.07

2.7

1.9

—

(3043924) Respiratory syncytial virus RNA [Identifier] in Specimen by NAA with probe detection

4.56

6.43

2.3

1.7

—

(3038288) Influenza virus B RNA [Presence] in Specimen by NAA with probe detection

4.22

5.65

2.3

1.8

—

(3019198) Lymphocytes [#/volume] in Blood

266

3.71

4.61

10.0

5.7

1.9

e9/l

0.08

233

(40760892) CBC W Ordered Manual Differential panel - Blood

109

3.27

4.51

6.1

5.9

—

(3011960) Natriuretic peptide B [Mass/volume] in Serum or Plasma

4.01

4.04

4.4

2.3

145.9

152.2

ng/l

0.05

(3026008) Bacteria identified in Urine by Culture

156

2.91

3.87

4.0

3.0

—

(3013650) Neutrophils [#/volume] in Blood by Automated count

304

3.48

3.82

21.1

10.4

3.9

4.1

e9/l

0.27

262

(3042194) Human metapneumovirus RNA [Presence] in Specimen by NAA with probe detection

7.53

3.81

1.5

1.7

—

(42870588) Differential panel, method unspecified - Blood

174

2.87

3.77

9.1

5.1

—

(3002179) Metamyelocytes/100 leukocytes in Blood

3.72

3.44

5.9

3.3

0.8

0.5

—

(3032080) INR in Blood by Coagulation assay

202

2.65

3.23

16.1

7.3

1.7

1.2

inr

0.99

(3025159) Blasts/100 leukocytes in Blood

3.52

3.19

6.2

3.7

0.0

—

(3032035) Polymorphonuclear cells/100 leukocytes in Blood

8.19

3.13

4.5

1.8

51.3

63.6

—

(3030905) Polymorphonuclear cells [#/volume] in Blood

8.19

3.13

3.8

1.8

3.5

6.0

e9/l

—

(3051714) Fibrin D-dimer FEU [Mass/volume] in Platelet poor plasma

108

2.67

3.03

1.3

1.7

1.0

1.1

mg/l

0.11

(3016771) Amylase [Enzymatic activity/volume] in Serum or Plasma

164

2.54

2.99

3.5

2.4

53.6

57.4

u/l

0.36

151

(3016431) Calcium.ionized [Moles/volume] adjusted to pH 7.4 in Serum or Plasma

254

2.63

2.98

11.1

7.5

1.2

mmol/l

0.17

217

(40762366) Oxygen capacity [Volume Fraction] in Arterial blood

4.24

2.81

10.0

6.7

—

(3017181) Myelocytes/100 leukocytes in Blood

3.18

2.74

6.5

3.5

0.8

—

(3018418) pH of Serum or Plasma

156

2.37

2.57

6.3

5.1

7.4

—

(3021440) Promyelocytes/100 leukocytes in Blood

3.16

2.54

7.0

3.7

0.2

0.3

—

(3030467) Casts [#/volume] in Urine by Automated count

149

2.35

2.51

5.3

2.8

0.0

0.5

e6/l

3.25

115

(3040853) Adenovirus DNA [Identifier] in Specimen by NAA with probe detection

5.44

2.47

1.7

—

(3031040) Bacteria [#/volume] in Urine by Automated count

341

2.69

2.44

7.5

4.2

—

48.0

—

(42529200) Cancer Ag 15-3 [Units/volume] in Serum or Plasma by Immunoassay

6.70

2.42

8.8

6.4

42.0

140.4

u/ml

—

(3022806) Fractional oxyhemoglobin in Capillary blood

6.70

2.42

1.8

2.8

90.8

89.3

—

(3018095) Leukocytes [#/volume] in Urine

187

2.25

2.35

5.7

3.4

15.9

50.8

e6/l

0.84

135

(3043849) Epstein Barr virus DNA [Units/volume] (viral load) in Serum or Plasma by NAA with probe detection

5.95

2.26

1.4

1.3

—

(3019060) Gas panel - Arterial blood

3.06

2.23

6.7

4.3

—

(586526) SARS-CoV-2 (COVID-19) RNA [Presence] in Nasopharynx by NAA with probe detection

3.54

2.19

2.0

1.4

—

(3014007) Fractional oxyhemoglobin in Arterial blood

3.54

2.19

6.1

8.5

94.9

94.1

—

(3029287) Urinalysis microscopic panel [#/volume] - Urine by Automated count

184

2.15

2.12

5.6

2.9

—

(40760888) Immunoglobulin light chains.free panel - Serum

5.35

2.11

13.2

4.5

—

(36304419) Bacteria [Presence] in Urine

151

2.15

2.05

5.4

2.7

—

(3035995) Alkaline phosphatase [Enzymatic activity/volume] in Serum or Plasma

406

2.68

2.05

16.9

7.5

88.2

84.5

u/l

0.30

378

(3020891) Body temperature

3.64

2.03

4.0

4.7

—

(3048929) Epstein Barr virus Ab [Presence] in Serum

4.05

1.99

1.3

1.4

—

(3014162) Mycobacterium tuberculosis DNA [Presence] in Specimen by NAA with probe detection

4.05

1.99

3.2

2.2

—

(3004588) Protein electrophoresis panel - Serum or Plasma

2.94

1.96

7.1

3.1

—

(3007853) Bacteria identified in Skin by Aerobe culture

2.65

1.91

1.4

1.5

—

(3001079) Blood group antibody screen [Presence] in Serum or Plasma

217

2.06

1.91

5.9

4.2

—

(3021337) Troponin I.cardiac [Mass/volume] in Serum or Plasma

2.21

1.89

6.2

3.1

385.6

96.9

ng/l

0.57

(3024135) Streptococcus.beta-hemolytic [Presence] in Throat by Organism specific culture

2.21

1.89

1.8

1.5

—

(3043109) Cytology report of Tissue fine needle aspirate Cyto stain

4.45

1.86

1.2

—

(3027315) Oxygen [Partial pressure] in Blood

4.45

1.86

3.8

4.8

8.6

8.2

kpa

—

(37019628) Gastrointestinal bacterial pathogens panel - Stool by NAA with probe detection

4.45

1.86

1.0

1.2

—

(3013290) Carbon dioxide [Partial pressure] in Blood

4.45

1.86

3.8

4.8

4.4

4.8

kpa

—

(3051552) Clostridioides difficile toxin genes [Presence] in Stool by NAA with probe detection

2.77

1.83

1.1

1.4

—

(3000620) Complement C3 [Mass/volume] in Serum or Plasma

3.80

1.65

1.0

1.1

1.3

g/l

—

(3017766) Complement C4 [Mass/volume] in Serum or Plasma

3.80

1.65

1.0

1.1

0.2

0.3

g/l

—

(3037467) Urinalysis macro (dipstick) panel - Urine

349

2.08

1.56

6.7

3.9

—

(3008909) Norovirus RNA [Presence] in Stool by NAA with probe detection

3.54

1.55

1.2

1.1

—

(40768443) Skin Pathology biopsy report

3.06

1.55

1.2

1.4

—

(3020779) Urea [Moles/volume] in Serum or Plasma

2.61

1.54

3.9

6.1

8.3

9.0

mmol/l

—

(3044254) Respiratory syncytial virus RNA [Presence] in Specimen by NAA with probe detection

3.32

1.47

3.2

2.3

—

(46235759) Influenza virus B RNA [Presence] in Nasopharynx by NAA with probe detection

3.32

1.47

3.4

2.3

—

(3016293) Bicarbonate [Moles/volume] in Serum or Plasma

2.41

1.45

6.0

7.1

25.2

25.0

mmol/l

—

(3000991) Gas panel - Venous blood

2.35

1.41

6.7

6.9

—

(3042936) Bacteria identified in Isolate by Culture

2.10

1.37

1.8

2.2

—

(3007220) Creatine kinase [Enzymatic activity/volume] in Serum or Plasma

146

1.82

1.29

5.6

2.0

149.4

112.6

u/l

0.47

139

(3019900) Cholesterol [Moles/volume] in Serum or Plasma

484

0.52

1.27

4.7

4.4

4.7

4.6

mmol/l

0.36

442

(3001308) Cholesterol in LDL [Moles/volume] in Serum or Plasma

492

0.51

1.26

4.9

5.0

2.8

2.7

mmol/l

0.41

448

(3006217) Methemoglobin/Hemoglobin.total in Arterial blood

2.45

1.22

7.8

8.0

0.7

—

(3028653) Carboxyhemoglobin/Hemoglobin.total in Arterial blood

2.45

1.22

7.8

8.0

1.6

1.4

—

(3019902) Methicillin resistant Staphylococcus aureus [Presence] in Specimen by Organism specific culture

2.22

1.21

10.6

4.9

—

(4010399)

2.51

1.17

1.7

1.3

—

(3023602) Cholesterol in HDL [Moles/volume] in Serum or Plasma

480

0.55

1.11

4.4

1.4

1.5

mmol/l

0.86

434

(3008898) HLA-B27 [Presence]

2.51

1.11

1.2

1.0

—

(3021879) Hepatitis B virus core Ab [Presence] in Serum

2.13

1.10

1.2

1.6

—

(3000494) Fungus identified in Specimen by Culture

1.93

1.06

1.3

—

(3018405) Lactate [Moles/volume] in Arterial blood

2.39

1.05

3.4

7.1

1.2

1.3

mmol/l

—

(3035350) Ketones [Presence] in Urine by Test strip

250

1.62

0.98

6.0

3.8

0.0

estimate

—

(36031861) Influenza virus A and B and SARS-CoV-2 (COVID-19) and Respiratory syncytial virus RNA panel - Respiratory system specimen by NAA with probe detection

2.27

0.94

2.5

1.6

—

(3015736) pH of Urine

188

1.58

0.87

5.1

3.7

—

(3002256) Pathology report gross observation

1.88

0.86

1.8

1.3

—

(3022948) Iron [Moles/volume] in Serum or Plasma

1.76

0.83

1.7

1.9

9.4

13.0

umol/l

0.85

(3048773) Triglyceride [Moles/volume] in Serum or Plasma --fasting

462

0.62

0.81

4.0

3.9

1.4

1.3

mmol/l

0.54

415

(3012544) pH of Venous blood

1.82

0.80

2.9

3.6

—

(3022313) Gas panel - Capillary blood

2.28

0.78

4.6

4.2

—

(3019050) Tissue transglutaminase IgA Ab [Units/volume] in Serum

120

0.53

0.78

1.0

1.2

—

0.7

—

(3044889) 12 lead EKG panel

352

1.56

0.75

5.6

3.5

—

(46236098) ABO and Rh group [Type] in Blood by Confirmatory method

103

1.62

0.74

2.5

2.3

—

(40761536) Microorganisms panel - Urine sediment

1.80

0.73

5.7

3.8

—

(46235355) HIV 1 and 2 tests - Meaningful Use set

1.62

0.72

1.3

1.8

—

(40763086) Leukocyte esterase [Presence] in Urine by Automated test strip

195

1.50

0.72

6.8

4.1

—

(4035726)

1.76

0.71

1.6

1.3

—

(3009261) Glucose [Presence] in Urine by Test strip

254

1.47

0.69

6.2

3.8

0.0

estimate

—

(3019284) Hepatitis B virus surface Ag [Presence] in Serum

1.65

0.69

1.3

1.5

—

(3021601) Nitrite [Presence] in Urine by Test strip

255

1.46

0.67

7.6

5.1

0.0

estimate

—

(3029937) Albumin [Presence] in Urine by Test strip

142

1.50

0.66

7.5

4.1

0.0

estimate

—

(3004789) Transferrin [Mass/volume] in Serum or Plasma

1.65

0.64

1.6

1.9

2.3

g/l

0.01

(3017143) Hepatitis C virus Ab [Presence] in Serum

1.63

0.61

1.5

—

(3023421) Hepatitis B virus surface Ab [Units/volume] in Serum

0.00

0.61

0.0

1.4

—

141.3

—

(3000492) Spirometry study

1.64

0.56

1.8

1.4

—

(3019832) Treponema pallidum Ab [Presence] in Serum

1.64

0.56

1.2

1.6

—

(3019800) Troponin T.cardiac [Mass/volume] in Serum or Plasma

194

1.40

0.55

5.5

3.5

24.1

30.7

ng/l

0.41

127

(3041942) Cyclic citrullinated peptide Ab [Units/volume] in Serum

1.52

0.52

1.2

1.3

51.8

10.5

u/ml

—

(3007164) IgA [Mass/volume] in Serum or Plasma

104

1.46

0.49

5.5

1.4

2.1

g/l

—

(40768797) Stomach Pathology biopsy report

1.44

0.44

1.1

1.3

—

(1761482) Bacteria [#/volume] in Urine by Culture

0.00

0.42

0.0

4.8

—

(3021589) Normoblasts [#/volume] in Blood

242

1.30

0.39

23.5

10.1

0.0

e9/l

0.50

197

(3033319) Streptococcus pyogenes Ag [Presence] in Throat

1.42

0.33

1.3

1.5

—

(3044640) Blood type and Crossmatch panel - Blood

150

1.29

0.31

2.9

2.3

—

(3003694) ABO and Rh group [Type] in Blood

138

0.75

0.30

1.4

1.3

—

(3011397) Hemoglobin [Presence] in Urine by Test strip

116

1.27

0.25

6.8

3.8

—

(40761535) Cells panel - Urine sediment

1.31

0.23

4.4

3.7

—

(3021584) Pregnancy associated plasma protein A [Units/volume] in Serum or Plasma

0.00

0.21

0.0

1.5

—

(3051387) C reactive protein [Mass/volume] in Capillary blood

0.00

0.21

0.0

5.5

—

24.9

—

(3015816) F5 gene p.Arg506Gln [Presence] in Blood or Tissue by Molecular genetics method

0.00

0.21

0.0

1.0

—

(3003740) Influenza virus B Ag [Presence] in Specimen

0.00

0.21

0.0

1.1

—

(3038515) Glucose [Moles/volume] in Venous blood

0.00

0.21

0.0

3.2

—

6.5

—

(3018387) Mycoplasma pneumoniae IgG Ab [Units/volume] in Serum

0.00

0.21

0.0

1.0

—

(3027544) Mycobacterium sp identified in Sputum by Organism specific culture

0.00

0.21

0.0

2.9

—

(3008037) Lactate [Moles/volume] in Venous blood

0.00

0.21

0.0

3.2

—

1.1

—

(3002523) Influenza virus A Ag [Presence] in Specimen

0.00

0.21

0.0

1.1

—

(3009041) Cardiolipin IgG Ab [Units/volume] in Serum by Immunoassay

0.00

0.21

0.0

1.2

—

6.8

—

(3045783) Sodium and Potassium panel [Moles/volume] - Serum or Plasma

1.17

0.18

9.3

6.6

—

(3018006) Microscopic observation [Identifier] in Cervix by Cyto stain.thin prep

0.72

0.18

1.4

1.3

—

(3012516) Albumin [Mass/volume] in Urine

130

1.21

0.18

1.6

3.0

95.9

656.0

mg/l

—

(40758558) Short blood count panel - Blood

141

1.19

0.16

13.4

7.1

—

(1761868) Lipid panel - Serum or Plasma

158

0.85

0.14

2.6

2.8

—

(3009542) Hematocrit [Volume Fraction] of Blood

465

0.86

0.12

30.2

13.3

38.6

39.8

0.32

333

(43054914) Glucose tolerance 2 hours panel - Serum or Plasma

1.15

0.10

1.0

1.6

—

(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection

325

0.90

0.09

5.0

3.0

—

(3022145) Colonoscopy Study observation

1.12

0.09

1.2

—

(3003510) Neisseria gonorrhoeae DNA [Presence] in Urine by NAA with probe detection

1.08

0.09

1.7

—

(3009201) Thyrotropin [Units/volume] in Serum or Plasma

458

1.14

0.08

5.5

4.6

1.9

1.8

mu/l

0.12

415

(3020682) Albumin/Creatinine [Ratio] in Urine

140

1.10

0.05

2.1

3.6

9.2

10.1

mg/mmol

—

(3041096) Erythrocytes [Presence] in Urine by Automated

141

1.09

0.04

5.9

3.5

—

(40768804) Tissue Pathology biopsy report

191

1.07

0.03

2.7

2.1

—

(3013512) EKG study

142

1.08

0.03

4.5

3.7

—

(43054903) Holo-transcobalamin II [Moles/volume] in Serum

187

0.95

0.01

2.8

1.9

92.0

94.2

pmol/l

0.10

(3001784) Prostate Specific Ag Free/Prostate specific Ag.total in Serum or Plasma

108

1.02

0.00

4.1

4.2

15.6

23.0

—

(44816844) Macroprolactin [Units/volume] in Serum or Plasma

0.00

0.0

1.2

—

(21494670) JAK2 gene exon 14 targeted mutation analysis in Blood or Tissue by Molecular genetics method

0.00

0.0

1.0

—

(40768441) Liver Pathology biopsy report

0.00

0.0

1.0

—

(3053028) Streptococcus sp identified in Specimen by Organism specific culture

0.00

0.0

1.0

—

(3014973) Borrelia burgdorferi IgM Ab [Units/volume] in Cerebral spinal fluid

0.00

0.0

1.0

—

(40762485) Glomerular basement membrane Ab [Units/volume] in Serum by Immunoassay

0.00

0.0

1.2

—

(3049539) Genetic diseases [Identifier] in Blood or Tissue by FISH Nominal

0.00

0.0

1.0

—

(3000855) Microscopic observation [Identifier] in Vaginal fluid by Gram stain

0.00

0.0

1.2

—

(3050129) First trimester maternal screen panel - Serum or Plasma

0.00

0.0

1.0

—

(3012413) Glucose [Moles/volume] in Serum or Plasma --2 hours post meal

0.00

0.0

1.3

—

(3035285) Chloride [Moles/volume] in Venous blood

0.00

0.0

2.6

—

110.6

—

(4268621)

0.00

0.0

2.0

—

(3024950) Chlamydia trachomatis DNA [Presence] in Urine by NAA with probe detection

0.96

0.00

1.8

1.9

—

(3033705) Calcium.ionized [Moles/volume] in Venous blood

0.00

0.0

2.6

—

(3027231) Wheat IgE Ab [Units/volume] in Serum

0.00

0.0

1.6

—

(3035933) Granulocytes/100 leukocytes in Blood

0.00

0.0

1.2

—

(3017817) Protein [Mass] in Urine collected for unspecified duration

0.00

0.0

7.8

—

(3049506) Microalbumin [Mass/time] in Urine collected for unspecified duration

0.00

0.0

1.4

—

(3029511) Human papilloma virus DNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.2

—

(40768806) Pleura Pathology biopsy report

0.00

0.0

1.2

—

(3020564) Creatinine [Moles/volume] in Serum or Plasma

528

1.04

0.00

36.5

15.6

70.1

76.4

umol/l

1.36

528

(3036603) Volume of Urine

0.00

0.0

1.6

—

(21494434) Karyotype in Bone marrow

0.00

0.0

1.0

—

(3019145) Choriogonadotropin.beta subunit free [Mass/volume] in Serum or Plasma

0.00

0.0

1.6

—

(21492711) Cytomegalovirus IgG Ab avidity [Presence] in Serum or Plasma by Immunoassay

0.00

0.0

1.1

—

(3045788) Cell count panel - Pleural fluid

0.00

0.0

1.2

—

(3017569) Oxygen content in Arterial blood

0.00

0.0

15.2

—

(36033641) SARS-CoV-2 (COVID-19) Ag [Presence] in Upper respiratory specimen by Rapid immunoassay

0.00

0.0

1.1

—

(42870365) C reactive protein [Mass/volume] in Blood by High sensitivity method

0.00

0.0

2.6

—

(3000093) Morphology [Interpretation] in Blood Narrative

0.00

0.0

1.1

—

(3039443) Prostate specific Ag panel - Serum or Plasma

0.00

0.0

1.2

—

(3019225) pH of Specimen

1.00

0.00

8.2

3.5

—

(3005570) Glucose [Moles/volume] in Urine

0.00

0.0

3.0

—

(3004915) Chlamydophila pneumoniae IgA Ab [Units/volume] in Serum

0.00

0.0

1.0

—

(3019539) Treponema pallidum Ab [Titer] in Serum by Hemagglutination

0.00

0.0

2.4

—

(4281824)

0.00

0.0

1.0

—

(3025018) Bordetella pertussis Ab [Titer] in Serum

0.00

0.0

1.2

—

(3044242) Glucose [Moles/volume] in Arterial blood

0.00

0.0

15.0

—

(3035320) C reactive protein [Mass/volume] in Body fluid

0.00

0.0

2.4

—

(3027901) Hemoglobin [Mass/volume] in Arterial cord blood

0.00

0.0

1.0

—

174.6

—

(40761511) CBC panel - Blood by Automated count

518

1.04

0.00

32.3

12.8

—

(3041354) Potassium [Moles/volume] in Venous blood

0.00

0.0

2.6

—

3.9

—

(21492888) Glucose tolerance 2 hours gestational panel - Serum or Plasma

0.00

0.0

2.0

—

Mortality – FinRegistry

↥

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

↥

Index endpoint: DRUGADVERS_FEVER – Drug-induced fever

GWS hits: -

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

≡ Risteys

FG R12 + FR

FinnGen R11 + FinRegistry

FinnGen R10 + FinRegistry

FinnGen R10

FinnGen R9

FinnGen R8

FinnGen R7

FinnGen R6

FinnGen R5

FinnGen R4

FinnGen R3

Drug-induced fever

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

1. Apply sex-specific rule

2. Check conditions

3. Check pre-conditions, main-only, mode, registry filters

4. Check minimum number of events

5. Include endpoints

6. Filter based on genotype QC (FinnGen only)

All original rules

Similar endpoints

Case counts by codes

Upset plot

Case counts by code for Drug-induced fever (DRUGADVERS_FEVER)

Summary Statistics

-FinRegistry-

-FinnGen-

Key figures

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

CodeWAS (R11)

Matched cohort

LabWAS

Mortality – FinRegistry

Relationships between endpoints