Abscess of tendon sheath

M13_ABSCTENDON

synovitis: ['Inflammation of the SYNOVIAL MEMBRANE [ MeSH ]']

Endpoint definition

↥

Endpoint definition steps	FinnGen
Phenotype data	520210
1. Apply sex-specific rule None	520210
2. Check conditions None	520210
3. Check pre-conditions, main-only, mode, registry filters Registry filters: Hospital discharge: ICD-10 — M65.0 Cause of death: ICD-10 — M65.0 2 out of 7 registries used, show all original rules.	215
4. Check minimum number of events None	215
5. Include endpoints None	215
6. Filter based on genotype QC (FinnGen only)	215

Control definitions (FinnGen only)

Control exclude: M13_SOFTTISSUE

Extra metadata

Level in the ICD hierarchy: 4
First used in FinnGen datafreeze: DF2
Parent code in ICD-10: M65
Name in latin: Abscessus vaginae tendinis

NAME	M13_ABSCTENDON
CONTROL_EXCLUDE	M13_SOFTTISSUE
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX
INCLUDE
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10	M650
HD_ICD_9	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
HD_ICD_8	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10	M650
COD_ICD_9	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
COD_ICD_8	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

Similar endpoints

↥

List of similar endpoints to Abscess of tendon sheath based on the number of shared cases.

Similar with more cases:

Similar with less cases:

None

Case counts by codes

↥

FinnGen case counts by registry codes:

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

Key figures

	All	Female	Male
Number of individuals
Whole population	1425	675	749
Only index persons	1365	650	715
Unadjusted period prevalence (%)
Whole population	0.02	0.02	0.02
Only index persons	0.03	0.02	0.03
Median age at first event (years)
Whole population	48.93	51.37	46.74
Only index persons	48.50	51.08	46.16

-FinnGen-

Key figures

	All	Female	Male
Number of individuals	215	126	89
Unadjusted period prevalence (%)	0.04	0.04	0.04
Median age at first event (years)	52.12	48.87	56.72

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS (R11)

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log₁₀(p-value) ≥ 6.

Matched cohort

Matched cases
188: Matched controls
1879

Code

Vocabulary

Description

Odds Ratio

-log₁₀(p)

N matched cases

N matched controls

M65.0

ICD-10 Finland

Abscess of tendon sheath

+∞

272.0

188

NDM40

NOMESCO Finland

Discission of sheath of tendon of wrist or hand

+∞

50.3

NDS00

NOMESCO Finland

Incision and debridement of infection of tendon of wrist or hand

+∞

42.3

QCB10

NOMESCO Finland

Major dressing of wound of skin of upper limb

30.9

22.1

QCB05

NOMESCO Finland

Revision of wound of skin of upper limb

86.5

21.2

M65.9

ICD-10 Finland

Synovitis and tenosynovitis, unspecified

26.0

19.7

WX204

NOMESCO Finland

Axillary plexus blockaced

21.7

19.3

M65.3

ICD-10 Finland

Trigger finger

30.2

18.3

M75.1

ICD-10 Finland

Rotator cuff syndrome

5.4

16.3

130

L02.4

ICD-10 Finland

Cutaneous abscess, furuncle and carbuncle of limb

17.8

16.2

G56.0

ICD-10 Finland

Carpal tunnel syndrome

6.9

16.1

N03AX16

ATC

pregabalin; oral

4.6

15.9

190

ACC51

NOMESCO Finland

Release of median nerve

9.7

15.5

WX203

NOMESCO Finland

Infraclavicular plexus blockade

18.0

13.8

M79.6

ICD-10 Finland

Pain in limb

3.7

13.7

267

ND2AA

NOMESCO Finland

Hand and fingers X-ray examination

6.7

13.4

M65.4

ICD-10 Finland

Radial styloid tenosynovitis [de Quervain]

43.4

13.4

ZXD05

NOMESCO Finland

Urgent procedure

3.5

12.9

312

N02AA59

ATC

codeine, combinations excl. psycholeptics; systemic

3.1

12.1

102

522

ZXA00

NOMESCO Finland

Right side

3.4

11.9

271

L03.1

ICD-10 Finland

Cellulitis of other parts of limb

14.9

11.7

M47.2

ICD-10 Finland

Other spondylosis with radiculopathy

9.0

11.5

J01FF01

ATC

clindamycin; systemic

3.3

11.4

286

M65.8

ICD-10 Finland

Other synovitis and tenosynovitis

26.9

11.3

N02AX02

ATC

tramadol; systemic, rectal

3.0

11.2

442

S18

ICPC

Laceration/cut

2.9

11.0

479

ZXD20

NOMESCO Finland

Day surgery

4.6

10.5

WX120

NOMESCO Finland

Intravenous local anesthesy of arm

116.1

10.5

NBG10

NOMESCO Finland

Acromioplastia

+∞

10.5

L03.0

ICD-10 Finland

Cellulitis of finger and toe

6.3

10.5

R4120

NOMESCO Finland

Occupational therapy

6.3

10.5

NBG15

NOMESCO Finland

Acromioplastia, arthroscopic

25.0

10.4

M01AH05

ATC

etoricoxib; oral

2.8

10.3

119

718

J01DB01

ATC

cefalexin; oral

3.7

9.8

166

1261

X59

ICD-10 Finland

Exposure to unspecified factor

3.4

9.4

179

N03AX12

ATC

gabapentin; oral

4.1

9.4

109

ZXE00

NOMESCO Finland

One hour or less

2.7

9.4

461

M01AE02

ATC

naproxen; oral, rectal

2.6

9.3

117

724

Z3226

NOMESCO Finland

Physiotherapist

3.5

9.1

169

M79.7

ICD-10 Finland

Fibromyalgia

17.3

8.7

NH3AA

NOMESCO Finland

Foot and toes X-ray examination

5.3

8.6

M65.1

ICD-10 Finland

Other infective (teno)synovitis

+∞

8.4

M19.1

ICD-10 Finland

Post-traumatic arthrosis of other joints

15.4

8.3

N02AJ06

ATC

codeine and paracetamol; systemic

2.6

8.1

373

A46

ICD-10 Finland

Erysipelas

3.7

8.0

113

M51.1

ICD-10 Finland

Lumbar and other intervertebral disc disorders with radiculopathy

3.6

8.0

119

J01CR02

ATC

amoxicillin and beta-lactamase inhibitor; systemic

2.4

7.8

104

637

N06AX21

ATC

duloxetine; oral

4.4

7.8

N02BE01

ATC

paracetamol; systemic, rectal

3.2

7.8

165

1303

R4110

NOMESCO Finland

Physiotherapy

2.6

7.3

285

M79.0

ICD-10 Finland

Rheumatism, unspecified

31.3

7.2

M75.4

ICD-10 Finland

Impingement syndrome of shoulder

9.3

7.2

NK4XE

NOMESCO Finland

Joint ultrasound examination not elsewhere classified

5.0

7.2

M01AE03

ATC

ketoprofen; systemic, rectal

2.4

7.2

411

M48.0

ICD-10 Finland

Spinal stenosis

4.0

7.1

A02BC02

ATC

pantoprazole; systemic

2.3

7.0

126

874

ZXE10

NOMESCO Finland

More than one and less than three hours

2.4

7.0

424

ZXA05

NOMESCO Finland

Left side

2.7

7.0

237

M19.0

ICD-10 Finland

Primary arthrosis of other joints

4.4

6.9

X58

ICD-10 Finland

Exposure to other specified factors

3.4

6.8

116

NDQ20

NOMESCO Finland

Amputation of finger

41.6

6.8

M01AB05

ATC

diclofenac; systemic, rectal

2.3

6.8

126

884

TNX10

NOMESCO Finland

Arthrocentesis, unspecified region, unspecified region

5.2

6.8

M72.0

ICD-10 Finland

Palmar fascial fibromatosis [Dupuytren]

23.5

6.7

NH1CG

NOMESCO Finland

Ankle and foot extensive MRI examination with high intensity magnet

23.5

6.7

M03BX02

ATC

tizanidine; oral

2.3

6.7

121

835

M75.0

ICD-10 Finland

Adhesive capsulitis of shoulder

10.6

6.6

L08.8

ICD-10 Finland

Other specified local infections of skin and subcutaneous tissue

10.6

6.6

S46.0

ICD-10 Finland

Injury of muscle(s) and tendon(s) of the rotator cuff of shoulder

5.3

6.6

ACC59

NOMESCO Finland

Decompression and freeing of adhesions of peripheral nerve: other or unspecified

7.0

6.5

NH1AE

NOMESCO Finland

Ankle joint ultrasound examination

72.1

6.5

NDL52

NOMESCO Finland

Tenosynovectomy of hand

72.1

6.5

ND1CG

NOMESCO Finland

Wrist and hand extensive MRI examination with high intensity magnet

72.1

6.5

L97

ICD-10 Finland

Ulcer of lower limb, not elsewhere classified

8.6

6.4

L12

ICPC

Hand/finger symptom/complaint

3.3

6.3

105

QDB10

NOMESCO Finland

Major dressing of wound of skin of lower limb

6.1

6.3

ND2AE

NOMESCO Finland

Hand and fingers ultrasound examination

+∞

6.3

NBT60

NOMESCO Finland

Forcible manipulation of humeroscapular joint

+∞

6.3

NBA30

NOMESCO Finland

Exploration of joint of shoulder or upper arm, arthroscopic

27.7

6.3

NB2AT

NOMESCO Finland

Intra artrial injection of shoulder with ultrasound guidance

27.7

6.3

M10.9

ICD-10 Finland

Gout, unspecified

4.7

6.3

E10.3

ICD-10 Finland

Type 1 diabetes mellitus, With ophthalmic complications

8.1

6.2

M77.1

ICD-10 Finland

Lateral epicondylitis

4.9

6.2

NBL00

NOMESCO Finland

Suture or reinsertation of rotator cuff of shoulder

9.1

6.1

E10.7

ICD-10 Finland

Type 1 diabetes mellitus, With multiple complications

9.1

6.1

A10AC01

ATC

insulin (human); parenteral (insulins and analog. for injection, intermediate-acting)

4.1

6.1

NA1AA

NOMESCO Finland

Cervical spine X-ray examination without contrast

10.5

6.1

25000

ICD-8 Finland

Diabetes mellitus, Sine complicatione

10.5

6.1

A49.9

ICD-10 Finland

Bacterial infection, unspecified

3.5

6.0

Mortality – FinRegistry

↥

Association

Association between endpoint M13_ABSCTENDON and mortality.

Females

Parameter	HR [95% CI]	p-value
M13_ABSCTENDON	1.179 [0.9, 1.55]	0.235
Birth year	0.999 [0.99, 1.01]	0.723

During the follow-up period (1.1.1998 — 31.12.2019), 76 out of 589 females with M13_ABSCTENDON died.

Males

Parameter	HR [95% CI]	p-value
M13_ABSCTENDON	1.623 [1.22, 2.17]	0.001
Birth year	0.986 [0.98, 1.0]	0.004

During the follow-up period (1.1.1998 — 31.12.2019), 82 out of 624 males with M13_ABSCTENDON died.

Mortality risk

Mortality risk for people of age

years, who have M13_ABSCTENDON.

N-year risk	Females	Males
1	0.108%	0.294%
5	0.704%	1.659%
10	1.838%	4.204%
15	3.309%	8.465%
20	6.222%	14.247%

Relationships between endpoints

↥

Index endpoint: M13_ABSCTENDON – Abscess of tendon sheath

GWS hits: 1

Endpoint

Case Overlap

Survival Analysis

Genetic Correlations

Genetic Signals

N (Jaccard index)

HR [CI]

Extremity

rg [CI]

Extremity

Hits

Coloc Hits

FinRegistry

FinnGen

FinRegistry

FinnGen

Loading data

Abscess of tendon sheath

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

1. Apply sex-specific rule

2. Check conditions

3. Check pre-conditions, main-only, mode, registry filters

4. Check minimum number of events

5. Include endpoints

6. Filter based on genotype QC (FinnGen only)

Similar endpoints

Case counts by codes

Summary Statistics

-FinRegistry-

Key figures

-FinnGen-

Key figures

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS (R11)

Matched cohort

Mortality – FinRegistry

Association

Females

Males

Mortality risk

Relationships between endpoints