Other disturbances of cerebral status of newborn

P16_OTH_DISTU_CEREBRAL_STATUS_NEWBO

No definition available.

Endpoint definition

↥

Endpoint definition steps	FinnGen
Phenotype data	520210
1. Apply sex-specific rule None	520210
2. Check conditions None	520210
3. Check pre-conditions, main-only, mode, registry filters Registry filters: Hospital discharge: ICD-10 — P91 Cause of death: ICD-10 — P91 2 out of 7 registries used, show all original rules.	44
4. Check minimum number of events None	44
5. Include endpoints None	44
6. Filter based on genotype QC (FinnGen only)	44

Control definitions (FinnGen only)

Control exclude: P16_OTH_DISORD_ORIGINA_PERINA_PERIOD

Extra metadata

Level in the ICD hierarchy: 3
First used in FinnGen datafreeze: DF4
Parent code in ICD-10: P9
Name in latin: Aliae perturbationes status cerebralis neonati

NAME	P16_OTH_DISTU_CEREBRAL_STATUS_NEWBO
CONTROL_EXCLUDE	P16_OTH_DISORD_ORIGINA_PERINA_PERIOD
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX
INCLUDE
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10	P91
HD_ICD_9
HD_ICD_8
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10	P91
COD_ICD_9
COD_ICD_8
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

Similar endpoints

↥

List of similar endpoints to Other disturbances of cerebral status of newborn based on the number of shared cases.

Similar with more cases:

Similar with less cases:

None

Case counts by codes

↥

FinnGen case counts by registry codes:

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

Key figures

	All	Female	Male
Number of individuals
Whole population	1980	844	1132
Only index persons	857	361	496
Unadjusted period prevalence (%)
Whole population	0.03	0.02	0.03
Only index persons	0.02	0.01	0.02
Median age at first event (years)
Whole population	0.15	0.00	0.00
Only index persons	0.01	0.01	0.01

-FinnGen-

Key figures

	All	Female	Male
Number of individuals	44	15	29
Unadjusted period prevalence (%)	0.01	0.01	0.01
Median age at first event (years)	0.00	0.00	0.00

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS (R11)

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log₁₀(p-value) ≥ 6.

No data available

LabWAS

↥

(ID) Name

N Cases

N Controls

-log₁₀(p)

cases

controls

cases

controls

unit

-log₁₀(p)

N cases

N controls

(3009466) Valproate [Moles/volume] in Serum or Plasma

17.93

6.77

5.1

4.1

455.5

437.9

umol/l

—

(3022670) pH of Venous cord blood

7.50

2.97

1.0

—

(40758558) Short blood count panel - Blood

173

2.23

1.76

3.3

9.9

—

(3035995) Alkaline phosphatase [Enzymatic activity/volume] in Serum or Plasma

173

2.23

1.76

8.0

6.3

173.4

177.7

u/l

0.08

162

(3013115) Eosinophils [#/volume] in Blood

259

2.38

1.58

5.5

12.3

0.3

0.2

e9/l

0.57

211

(3000991) Gas panel - Venous blood

125

2.10

1.53

8.4

14.1

—

(3033658) Prothrombin time (PT) actual/Normal

101

2.11

1.47

5.1

11.5

74.4

82.0

0.83

101

(3012544) pH of Venous blood

127

2.05

1.46

6.2

12.6

—

(3023024) Carbon dioxide [Partial pressure] in Capillary blood

147

1.99

1.38

25.2

11.5

4.7

4.9

kpa

1.40

139

(3006315) Basophils [#/volume] in Blood

255

2.18

1.38

5.4

11.1

0.0

e9/l

0.01

203

(3001604) Monocytes [#/volume] in Blood

256

2.16

1.35

5.4

11.1

0.7

0.6

e9/l

0.07

204

(3013650) Neutrophils [#/volume] in Blood by Automated count

267

2.20

1.34

6.8

12.7

3.0

3.4

e9/l

0.51

219

(3014007) Fractional oxyhemoglobin in Arterial blood

2.83

1.25

8.8

37.2

96.5

96.9

—

(3019198) Lymphocytes [#/volume] in Blood

261

2.06

1.21

5.3

11.2

3.2

2.8

e9/l

0.55

215

(3006217) Methemoglobin/Hemoglobin.total in Arterial blood

2.68

1.18

8.8

35.4

0.7

—

(3028653) Carboxyhemoglobin/Hemoglobin.total in Arterial blood

2.68

1.18

8.8

35.4

1.2

1.1

—

(3035637) Corticotropin [Mass/volume] in Plasma

2.49

1.16

2.4

2.0

—

(3022313) Gas panel - Capillary blood

136

1.86

1.14

23.0

10.5

—

(42870588) Differential panel, method unspecified - Blood

212

1.88

1.14

4.0

11.6

—

(3014218) Bicarbonate [Moles/volume] standard in Arterial blood

2.55

1.12

8.0

32.5

22.4

23.8

mmol/l

—

(40771025) 25-Hydroxyvitamin D3+25-Hydroxyvitamin D2 [Moles/volume] in Serum or Plasma

137

1.84

1.11

6.3

5.0

79.0

71.1

nmol/l

0.72

127

(40765161) Human bocavirus DNA [Presence] in Specimen by NAA with probe detection

2.43

1.06

1.4

2.2

—

(3044640) Blood type and Crossmatch panel - Blood

100

1.76

0.88

2.3

4.0

—

(3029287) Urinalysis microscopic panel [#/volume] - Urine by Automated count

136

1.70

0.87

7.9

6.6

—

(3029879) Epithelial cells.squamous [#/volume] in Urine by Automated count

1.77

0.85

4.9

6.1

0.5

1.3

e6/l

—

(3011397) Hemoglobin [Presence] in Urine by Test strip

101

1.74

0.84

5.0

4.2

—

(3017446) Testosterone [Moles/volume] in Serum or Plasma

0.00

0.82

0.0

2.3

—

11.2

—

(3011371) Neisseria gonorrhoeae DNA [Presence] in Specimen by NAA with probe detection

0.00

0.82

0.0

2.1

—

(3027008) Opiates [Presence] in Urine

2.22

0.77

1.0

1.7

—

(3000764) Benzodiazepines [Presence] in Urine

2.22

0.77

1.0

1.7

—

(3027944) Amphetamines [Presence] in Urine

2.22

0.77

1.0

1.7

—

(3016879) Cocaine [Presence] in Urine

2.22

0.77

1.0

1.7

—

(3024135) Streptococcus.beta-hemolytic [Presence] in Throat by Organism specific culture

182

0.59

0.76

1.8

2.0

—

(3028300) Cannabinoids [Presence] in Urine

2.12

0.75

1.0

1.7

—

(3028626) Oxygen [Partial pressure] in Capillary blood

142

1.59

0.71

27.5

10.7

9.5

9.7

kpa

0.25

134

(3043924) Respiratory syncytial virus RNA [Identifier] in Specimen by NAA with probe detection

1.70

0.69

4.7

2.3

—

(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection

360

0.59

0.69

4.1

—

(3026008) Bacteria identified in Urine by Culture

1.73

0.65

4.3

3.3

—

(3030306) Epithelial cells.non-squamous [#/volume] in Urine by Automated count

1.63

0.65

4.7

5.7

0.1

0.5

e6/l

—

(3005719) IgG [Mass/volume] in Serum or Plasma

1.62

0.63

1.6

5.5

9.7

7.7

g/l

—

(3021589) Normoblasts [#/volume] in Blood

255

1.55

0.60

5.2

12.6

0.0

e9/l

0.00

186

(3047007) Chlamydophila sp Ab [Presence] in Serum

0.00

0.60

0.0

1.3

—

(3007220) Creatine kinase [Enzymatic activity/volume] in Serum or Plasma

1.63

0.59

4.9

2.6

739.6

756.9

u/l

—

(3002582) Erythrocytes [#/volume] in Urine

130

1.50

0.55

8.4

6.5

5.8

511.2

e6/l

0.53

102

(3023103) Potassium [Moles/volume] in Serum or Plasma

311

1.61

0.53

28.4

18.8

4.0

4.1

mmol/l

0.28

300

(3019550) Sodium [Moles/volume] in Serum or Plasma

311

1.61

0.53

28.9

18.9

139.0

139.1

mmol/l

0.05

304

(3038288) Influenza virus B RNA [Presence] in Specimen by NAA with probe detection

1.66

0.52

4.9

2.3

—

(3030467) Casts [#/volume] in Urine by Automated count

123

1.47

0.50

5.7

6.4

0.0

0.5

e6/l

1.26

(3037467) Urinalysis macro (dipstick) panel - Urine

211

1.43

0.47

8.1

5.2

—

(40764999) Glomerular filtration rate/1.73 sq M.predicted [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (CKD-EPI)

115

1.46

0.47

11.5

6.2

116.8

107.0

ml/min/173m2

—

(3023368) Bacteria identified in Blood by Culture

1.55

0.46

4.6

4.4

—

(3016293) Bicarbonate [Moles/volume] in Serum or Plasma

154

1.41

0.44

28.6

15.5

24.5

24.4

mmol/l

0.04

154

(3030366) Cystatin C [Mass/volume] in Serum or Plasma

1.43

0.44

21.6

24.2

1.2

1.1

mg/l

—

(36304419) Bacteria [Presence] in Urine

126

1.42

0.43

5.9

6.1

—

(3015736) pH of Urine

117

1.43

0.43

8.3

4.1

—

(3011648) Oxygen content in Venous blood

0.00

0.42

0.0

25.6

—

11.9

—

(3023511) Choriogonadotropin [Units/volume] in Urine

0.00

0.42

0.0

1.3

—

(3000494) Fungus identified in Specimen by Culture

1.53

0.42

1.8

1.6

—

(3021387) Prolactin [Units/volume] in Serum or Plasma

0.00

0.41

0.0

1.5

—

455.8

—

(3050129) First trimester maternal screen panel - Serum or Plasma

0.00

0.41

0.0

1.5

—

(3004915) Chlamydophila pneumoniae IgA Ab [Units/volume] in Serum

0.00

0.41

0.0

1.3

—

(3013826) Glucose [Moles/volume] in Serum or Plasma

215

1.38

0.40

10.8

12.5

5.5

5.8

mmol/l

0.37

202

(3028026) IgM [Mass/volume] in Serum or Plasma

1.49

0.37

1.3

2.9

0.9

1.1

g/l

—

(3048773) Triglyceride [Moles/volume] in Serum or Plasma --fasting

149

1.35

0.36

3.7

3.2

1.1

mmol/l

0.08

140

(3044938) Influenza virus A RNA [Presence] in Specimen by NAA with probe detection

1.41

0.33

4.9

2.4

—

(3033319) Streptococcus pyogenes Ag [Presence] in Throat

124

1.32

0.29

1.6

2.3

—

(3007853) Bacteria identified in Skin by Aerobe culture

0.66

0.29

1.8

—

(36660697) Celiac disease serology panel - Serum

0.67

0.27

1.2

1.3

—

(3014326) Insulin-like growth factor-I [Moles/volume] in Serum or Plasma

1.32

0.24

7.0

4.2

13.8

19.9

nmol/l

—

(1002102) Choriogonadotropin.intact+Beta subunit [Mass/volume] in Serum or Plasma

0.00

0.21

0.0

1.5

—

(3005715) Vancomycin [Mass/volume] in Serum or Plasma

0.00

0.21

0.0

6.4

—

10.3

—

(40758895) Direct antiglobulin test.complement C3d specific reagent [Presence] on Red Blood Cells

0.00

0.21

0.0

3.2

—

(3008757) Leukocyte morphology finding [Identifier] in Blood

0.00

0.21

0.0

7.9

—

(40758897) Direct antiglobulin test.IgG specific reagent [Presence] on Red Blood Cells

0.00

0.21

0.0

3.2

—

(3044491) Cholesterol non HDL [Mass/volume] in Serum or Plasma

0.00

0.21

0.0

1.0

—

(3000093) Morphology [Interpretation] in Blood Narrative

0.00

0.21

0.0

1.2

—

(3009445) Proteinase 3 Ab [Units/volume] in Serum

0.00

0.21

0.0

1.1

—

(3002109) Cholesterol in LDL/Cholesterol in HDL [Mass Ratio] in Serum or Plasma

0.00

0.21

0.0

1.0

—

(3022145) Colonoscopy Study observation

0.00

0.21

0.0

1.1

—

(3003284) Neutrophil cytoplasmic Ab.perinuclear [Titer] in Serum by Immunofluorescence

0.00

0.21

0.0

1.3

—

(3049804) Myeloperoxidase IgG Ab [Units/volume] in Serum

0.00

0.21

0.0

1.1

—

(3016018) Differential panel - Cerebral spinal fluid

0.00

0.21

0.0

6.4

—

(36305247) Microscopic observation [Identifier] in Isolate by Gram stain

0.00

0.21

0.0

1.8

—

(3019900) Cholesterol [Moles/volume] in Serum or Plasma

158

1.24

0.21

4.8

3.5

4.1

mmol/l

0.12

152

(3020321) Streptococcus agalactiae [Presence] in Vaginal fluid by Organism specific culture

0.00

0.20

0.0

1.6

—

(3018006) Microscopic observation [Identifier] in Cervix by Cyto stain.thin prep

0.00

0.20

0.0

1.1

—

(46236098) ABO and Rh group [Type] in Blood by Confirmatory method

1.26

0.18

2.6

3.7

—

(3020460) C reactive protein [Mass/volume] in Serum or Plasma

355

1.27

0.16

22.5

13.2

26.9

22.8

mg/l

0.29

233

(3001308) Cholesterol in LDL [Moles/volume] in Serum or Plasma

152

1.19

0.15

5.1

3.4

2.5

2.4

mmol/l

0.20

143

(3018095) Leukocytes [#/volume] in Urine

152

1.19

0.15

12.2

7.7

27.9

30.7

e6/l

0.05

104

(40761511) CBC panel - Blood by Automated count

334

1.23

0.15

15.1

9.2

—

(3001079) Blood group antibody screen [Presence] in Serum or Plasma

115

1.19

0.12

3.0

5.0

—

(3023602) Cholesterol in HDL [Moles/volume] in Serum or Plasma

156

1.15

0.10

4.9

3.2

1.3

1.4

mmol/l

0.61

148

(3006923) Alanine aminotransferase [Enzymatic activity/volume] in Serum or Plasma

307

1.16

0.09

13.4

10.5

48.2

26.7

u/l

0.50

297

(40760892) CBC W Ordered Manual Differential panel - Blood

1.06

0.09

8.7

5.2

—

(3000515) Antithrombin actual/normal in Platelet poor plasma by Chromogenic method

1.06

0.09

2.3

9.5

62.8

82.4

—

(3018677) aPTT in Platelet poor plasma by Coagulation assay

1.08

0.08

2.9

7.7

35.4

31.8

—

(3007164) IgA [Mass/volume] in Serum or Plasma

182

1.08

0.03

1.3

2.0

1.8

1.3

g/l

—

(3044889) 12 lead EKG panel

107

0.92

0.02

1.4

2.2

—

(3003694) ABO and Rh group [Type] in Blood

115

1.06

0.00

1.2

1.8

—

(3006598) pH of Arterial cord blood

1.00

0.00

1.0

—

(21494429) FMR1 gene CGG repeat analysis in Blood or Tissue by Molecular genetics method

0.00

0.0

1.0

—

(3024471) HLA-A [Type]

0.00

0.0

1.0

—

(3024932) HLA-DR beta [Type]

0.00

0.0

1.1

—

(36033641) SARS-CoV-2 (COVID-19) Ag [Presence] in Upper respiratory specimen by Rapid immunoassay

0.00

0.0

1.1

—

(3016031) Almond IgE Ab [Units/volume] in Serum

0.00

0.0

1.1

—

2.7

—

(3044254) Respiratory syncytial virus RNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

3.0

—

(3007847) Interleukin 2 Receptor Soluble [Units/volume] in Serum or Plasma

0.00

0.0

1.8

—

1096.8

—

(46235759) Influenza virus B RNA [Presence] in Nasopharynx by NAA with probe detection

0.00

0.0

2.8

—

(3028369) Herpes simplex virus 1+2 DNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

2.5

—

(3046896) Herpes virus 6 DNA [Presence] in Cerebral spinal fluid by NAA with probe detection

0.00

0.0

1.6

—

(42870560) Thyrotropin [Units/volume] in Cord blood

1.03

0.00

1.0

16.1

8.7

mu/l

—

(3050380) Cytology report of Cervical or vaginal smear or scraping Cyto stain

0.00

0.0

1.0

—

(40763086) Leukocyte esterase [Presence] in Urine by Automated test strip

0.89

0.00

10.6

3.5

—

(3029715) Chromosome analysis.interphase [Interpretation] in Bone marrow by FISH Narrative

0.00

0.0

1.6

—

(3005702) Mycobacterium sp identified in Specimen by Organism specific culture

0.00

0.0

1.2

—

(3032352) Blasts [#/volume] in Cerebral spinal fluid

0.00

0.0

13.4

—

(3028433) Virus identified in Specimen by Culture

0.00

0.0

1.5

—

(3037677) Mycoplasma pneumoniae IgM Ab [Titer] in Cerebral spinal fluid

0.00

0.0

1.2

—

(3010380) Borrelia burgdorferi IgG Ab [Units/volume] in Cerebral spinal fluid

0.00

0.0

1.4

—

(3042299) inFLIXimab [Mass/volume] in Serum or Plasma

0.00

0.0

14.8

—

9.2

—

(1175556) inFLIXimab Ab [Units/volume] in Serum by Immunoassay

0.00

0.0

10.6

—

(44813793)

0.00

0.0

1.0

—

(3002621) Streptococcal DNAse B [Units/volume] in Serum

0.00

0.0

1.0

—

(3044212) Herpes simplex virus 1+2 IgM Ab [Presence] in Cerebral spinal fluid

0.00

0.0

1.6

—

(3041096) Erythrocytes [Presence] in Urine by Automated

0.96

0.00

11.3

3.1

—

(3041082) Glomerular basement membrane Ab [Titer] in Serum by Immunofluorescence

0.00

0.0

1.0

—

(3017115) Methotrexate [Moles/volume] in Serum or Plasma

0.00

0.0

37.6

—

0.7

—

(3045142) Bone marrow Pathology biopsy report

0.00

0.0

2.3

—

(3007798) IgG/Albumin [Mass Ratio] in Cerebral spinal fluid

0.00

0.0

1.0

—

(3013247) Albumin in CSF/Albumin in Serum or Plasma

0.00

0.0

1.0

—

2.6

—

(3023530) 17-Hydroxyprogesterone [Moles/volume] in Serum or Plasma

0.00

0.0

3.2

—

0.5

—

(42868421) Varicella zoster virus IgM Ab [Presence] in Cerebral spinal fluid by Immunoassay

0.00

0.0

1.4

—

(3042975) Streptococcus sp identified in Isolate by Organism specific culture

0.00

0.0

1.3

—

(3002823) Mycoplasma pneumoniae IgG Ab [Units/volume] in Cerebral spinal fluid

0.00

0.0

1.2

—

(40761849) Varicella zoster virus IgG Ab [Units/volume] in Cerebral spinal fluid by Immunoassay

0.00

0.0

1.4

—

(40760109) Toxoplasma gondii IgG Ab avidity [Ratio] in Serum by Immunoassay

0.00

0.0

1.0

—

(3014973) Borrelia burgdorferi IgM Ab [Units/volume] in Cerebral spinal fluid

0.00

0.0

1.4

—

(3035320) C reactive protein [Mass/volume] in Body fluid

0.00

0.0

2.0

—

(3022411) Androstenedione [Moles/volume] in Serum or Plasma

0.00

0.0

3.4

—

2.2

—

(3011166) Borrelia burgdorferi Ab [Presence] in Cerebral spinal fluid

0.00

0.0

1.4

—

(40762485) Glomerular basement membrane Ab [Units/volume] in Serum by Immunoassay

0.00

0.0

1.0

—

(3040893) Potassium [Moles/volume] in Capillary blood

0.00

0.0

2.2

—

4.1

—

(3042206) Streptococcus agalactiae Ag [Presence] in Vaginal fluid

0.00

0.0

1.2

—

(40759883) Oligoclonal Bands IgG [Presence] in Cerebral spinal fluid by Isoelectric focusing

0.00

0.0

1.0

—

(4027681)

0.00

0.0

1.0

—

(3028531) Enolase.neuron specific [Mass/volume] in Serum or Plasma

0.00

0.0

3.6

—

22.2

—

(3007302) Hemoglobin [Mass/volume] in Mixed venous blood

0.00

0.0

2.6

—

(3035999) Lactate [Moles/volume] in Cerebral spinal fluid

0.00

0.0

2.2

—

1.4

—

(3018921) Toxoplasma gondii IgA Ab [Units/volume] in Serum

0.00

0.0

1.0

—

(3032080) INR in Blood by Coagulation assay

0.91

0.00

2.3

5.3

—

1.4

—

(3000855) Microscopic observation [Identifier] in Vaginal fluid by Gram stain

0.00

0.0

1.2

—

(3024474) Albumin [Mass/volume] in Cerebral spinal fluid

0.00

0.0

1.0

—

95.5

—

(3002148) Methylenedioxymethamphetamine [Presence] in Urine by Screen method

0.00

0.0

1.9

—

(21494755) Public health laboratory ask at order entry panel

0.00

-0.00

0.0

1.3

—

(3015916) Alpha-1-Fetoprotein [Units/volume] in Serum or Plasma

0.00

-0.00

0.0

7.2

—

42.9

—

(21492888) Glucose tolerance 2 hours gestational panel - Serum or Plasma

0.00

-0.00

0.0

2.1

—

(3021513) Carbon dioxide [Partial pressure] in Mixed venous blood

0.00

-0.00

0.0

2.4

—

(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection

0.00

-0.00

0.0

1.4

—

(3038071) Oxygen [Partial pressure] in Mixed venous blood

0.00

-0.00

0.0

2.4

—

(3008733) Herpes simplex virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection

0.00

-0.00

0.0

1.4

—

(40768443) Skin Pathology biopsy report

0.00

-0.00

0.0

1.0

—

Mortality – FinRegistry

↥

Association

Association between endpoint P16_OTH_DISTU_CEREBRAL_STATUS_NEWBO and mortality.

Females

Parameter	HR [95% CI]	p-value
P16_OTH_DISTU_CEREBRAL_STATUS_NEWBO	8.612 [3.55, 20.9]	< 0.001
Birth year	0.991 [0.98, 1.0]	0.042

During the follow-up period (1.1.1998 — 31.12.2019), 54 out of 695 females with P16_OTH_DISTU_CEREBRAL_STATUS_NEWBO died.

Males

Parameter	HR [95% CI]	p-value
P16_OTH_DISTU_CEREBRAL_STATUS_NEWBO	11.971 [4.15, 34.5]	< 0.001
Birth year	0.989 [0.98, 1.0]	0.022

During the follow-up period (1.1.1998 — 31.12.2019), 64 out of 949 males with P16_OTH_DISTU_CEREBRAL_STATUS_NEWBO died.

Mortality risk

Mortality risk for people of age

years, who have P16_OTH_DISTU_CEREBRAL_STATUS_NEWBO.

N-year risk	Females	Males
1	0.702%	2.331%
5	4.077%	12.945%
10	9.595%	29.693%
15	18.288%	51.317%
20	29.999%	72.107%

Relationships between endpoints

↥

Index endpoint: P16_OTH_DISTU_CEREBRAL_STATUS_NEWBO – Other disturbances of cerebral status of newborn

GWS hits: -

Endpoint

Case Overlap

Survival Analysis

Genetic Correlations

Genetic Signals

N (Jaccard index)

HR [CI]

rg [CI]

Hits

Coloc Hits

FinRegistry

FinnGen

FinRegistry

FinnGen

Loading data

Other disturbances of cerebral status of newborn

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

1. Apply sex-specific rule

2. Check conditions

3. Check pre-conditions, main-only, mode, registry filters

4. Check minimum number of events

5. Include endpoints

6. Filter based on genotype QC (FinnGen only)

Similar endpoints

Case counts by codes

Summary Statistics

-FinRegistry-

Key figures

-FinnGen-

Key figures

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS (R11)

LabWAS

Mortality – FinRegistry

Association

Females

Males

Mortality risk

Relationships between endpoints