No definition available.
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
519972 |
1. Apply sex-specific ruleNone |
519972 |
2. Check conditionsNone |
519972 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
452 |
4. Check minimum number of eventsNone |
452 |
5. Include endpointsNone |
452 |
6. Filter based on genotype QC (FinnGen only) |
438 |
Control definitions (FinnGen only)
- Control exclude
- D3_COAGDEF_PURPUR_HAEMORRHAGIC
Extra metadata
- Level in the ICD hierarchy
- 4
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- D69
- Name in latin
- Thrombocytopenia secundaria
Similar endpoints
↥List of similar endpoints to
Secondary thrombocytopenia
based on the number of shared cases.
Similar with more cases:
- Purpura and other haemorrhagic conditions
- Coagulation defects, purpura and other haemorrhagic conditions
- Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
- Any event in hilmo or specialist outpatient
Similar with less cases:
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 3098 | 1537 | 1524 |
| Only index persons | 2347 | 1177 | 1170 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.04 | 0.04 | 0.04 |
| Only index persons | 0.04 | 0.04 | 0.04 |
| Median age at first event (years) | |||
| Whole population | 61.19 | 61.53 | 60.87 |
| Only index persons | 60.76 | 60.97 | 60.54 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 438 | 226 | 212 |
| Unadjusted period prevalence (%) | 0.09 | 0.08 | 0.10 |
| Median age at first event (years) | 61.95 | 60.76 | 63.22 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 452
- Matched controls
- 4520
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
D69.5
ICD-10 Finland
Secondary thrombocytopenia
+∞
307.7
423
*
D70.82
ICD-10 Finland
Drug-induced neutropenia
76.6
245.8
135
25
WW500
NOMESCO Finland
Blood transfusion
34.5
241.6
169
77
WD125
NOMESCO Finland
Demanding cystostatic therapy of methastized malignancy
18.3
158.1
145
114
117
Kela drug reimbursment
Leukaemia and other malignant diseases of the blood and bone marrow, and malignant diseases of the lymphatic tissue
16.4
124.6
117
94
WD105
NOMESCO Finland
Cystostatic therapy of methastized malignancy
17.2
115.6
104
77
XW000
NOMESCO Finland
Bone marrow biopsy
17.8
112.7
99
70
A49.9
ICD-10 Finland
Bacterial infection, unspecified
8.6
99.7
163
277
L03AA13
ATC
pegfilgrastim; parenteral
13.7
98.2
101
93
H02AB02
ATC
dexamethasone; systemic
8.3
97.8
169
305
D69.6
ICD-10 Finland
Thrombocytopenia, unspecified
157.9
96.5
99
8
WD405
NOMESCO Finland
Simple antiboidy therapy of methastized malignancy
17.9
90.9
78
52
L03AA02
ATC
filgrastim; parenteral
16.7
85.6
76
54
A04AA01
ATC
ondansetron; systemic, rectal
8.7
80.8
121
183
L03AA14
ATC
lipegfilgrastim; parenteral
21.0
79.1
62
34
Z51.5
ICD-10 Finland
Palliative care
8.4
76.9
118
183
ZX120
NOMESCO Finland
Intravenous
7.4
74.6
131
235
A03FA01
ATC
metoclopramide; systemic, rectal
5.7
73.6
219
644
C83.31
ICD-10 Finland
Diffuse lymphoma with large B cells
23.4
70.0
52
25
JN4BD
NOMESCO Finland
Extensive body CT
6.5
67.7
137
282
JN4AD
NOMESCO Finland
Body CT examination
6.6
66.5
131
262
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
8.7
65.3
93
131
JN6AD
NOMESCO Finland
CT of torso and neck
23.7
63.8
47
22
N02AA05
ATC
oxycodone; systemic
5.3
63.7
181
503
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
5.2
58.1
161
434
WD415
NOMESCO Finland
Demanding antibody therapy of methastized malignancy
19.4
54.8
44
25
R50.9
ICD-10 Finland
Fever, unspecified
5.1
54.3
148
391
TPH20
NOMESCO Finland
Insertion of central venous catheter through subclavian or brachiocephalic vein
12.4
50.2
52
47
B03XA02
ATC
darbepoetin alfa; parenteral
15.5
50.0
45
32
A04AA02
ATC
granisetron; systemic, transdermal
6.5
47.9
89
165
D69.3
ICD-10 Finland
Idiopathic thrombocytopenic purpura
+∞
43.4
41
*
M04AA01
ATC
allopurinol; systemic
4.6
41.5
123
341
TPX10
NOMESCO Finland
Implantation of vascular injection port
9.9
41.5
50
56
D64.9
ICD-10 Finland
Anaemia, unspecified
5.0
40.0
102
250
A41.9
ICD-10 Finland
Sepsis, unspecified
8.1
35.9
51
70
WF049
NOMESCO Finland
Radiotherapy of metastasis
8.4
35.1
48
63
128
Kela drug reimbursment
Cancers of female genital organs
11.4
33.5
36
34
J01EE01
ATC
sulfamethoxazole and trimethoprim; systemic
5.8
33.4
67
132
130
Kela drug reimbursment
Malignant tumour
4.7
33.1
89
226
GD1AA
NOMESCO Finland
Thorax X-ray examination
3.3
32.9
284
1537
WZC00
NOMESCO Finland
Treatment plan or consultation
3.2
32.8
230
1102
B01AB10
ATC
tinzaparin; parenteral
4.4
32.1
94
255
ZX112
NOMESCO Finland
Subcutaneous
9.1
29.2
37
44
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
3.9
29.0
104
325
WW300
NOMESCO Finland
Transfer of autologic stem cells
110.7
29.0
31
*
XZZ00
NOMESCO Finland
Active surveillance of a diagnosed cancer
10.3
25.2
29
30
WZC20
NOMESCO Finland
Multidisciplinary treatment meeting
4.6
25.0
64
155
H02AB06
ATC
prednisolone; systemic
2.8
24.7
270
1573
WD115
NOMESCO Finland
Multiple cystostatic therapy of methastized malignancy
9.4
24.4
30
34
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
3.8
24.4
87
269
L04AA06
ATC
mycophenolic acid; systemic
10.2
24.3
28
29
A04AA55
ATC
palonosetron, combinations; systemic
6.0
24.2
45
82
TK800
NOMESCO Finland
Hemodialysis
9.6
24.1
29
32
GD1DD
NOMESCO Finland
High resolution CT examination of lungs
5.2
23.5
51
107
TGC00
NOMESCO Finland
Bronchial lavation
6.9
23.0
37
58
N02AB03
ATC
fentanyl; nasal, sublingual, transdermal
5.8
22.6
43
80
WD135
NOMESCO Finland
Demanding cystostatic therapy of methastized malignancy
29.1
22.5
30
11
DM1AA
NOMESCO Finland
Paranasal sinuses X-ray examination without contrast
6.4
22.5
39
66
N17.9
ICD-10 Finland
Acute renal failure, unspecified
6.0
21.7
40
72
N03AX14
ATC
levetiracetam; systemic
7.7
21.5
31
43
D70.89
ICD-10 Finland
Neutropenic splenomegaly
19.0
21.2
32
18
WD305
NOMESCO Finland
Simple therapy of methastized malignancy with biomodifiers
19.5
20.7
31
17
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
5.4
20.6
43
87
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
2.6
20.5
193
1019
28711
ICD-8 Finland
Purpura and other haemorrhagic conditions, Thrombocytopenia symptomatica
+∞
19.9
19
*
YNB10
NOMESCO Finland
Collection of stem cells for transplant
+∞
19.9
19
*
J01MA12
ATC
levofloxacin; systemic
2.8
19.6
122
522
C03CA01
ATC
furosemide; systemic
2.6
19.6
170
859
Z51.1
ICD-10 Finland
Chemotherapy session for neoplasm
15.8
19.2
31
21
XX3DW
NOMESCO Finland
Time consuming IT work
3.3
19.2
85
300
TPH04
NOMESCO Finland
Cathetrisation of vein
2.7
19.2
138
636
JN3AD
NOMESCO Finland
Abdominal CT examination
3.3
18.9
82
286
ZX108
NOMESCO Finland
Inhalation
25.0
18.8
26
11
TPH90
NOMESCO Finland
Removal of fixed intravenous catheter
26.3
18.4
25
10
A41.5
ICD-10 Finland
Sepsis due to other Gram-negative organisms
5.4
18.2
37
73
UGC12
NOMESCO Finland
Flexible bronchoscopy
3.7
17.8
62
187
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
3.4
17.8
70
229
J18.9
ICD-10 Finland
Pneumonia, unspecified
2.5
17.5
146
719
A02BC02
ATC
pantoprazole; systemic
2.6
17.1
343
2475
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
3.4
17.0
69
230
C83.1
ICD-10 Finland
Mantle cell lymphoma
31.4
16.2
21
7
Y57
ICD-10 Finland
Adverse effects in the therapeutic use of other and unspecified drugs and medicaments
7.5
15.8
23
32
JN3BD
NOMESCO Finland
Extensive abdominal CT
3.2
15.7
69
241
B01AB05
ATC
enoxaparin; parenteral
2.3
15.7
173
957
R18
ICD-10 Finland
Ascites
7.3
15.4
23
33
H02AB09
ATC
hydrocortisone; systemic
6.6
14.7
24
38
J01MA14
ATC
moxifloxacin; systemic
3.2
14.5
64
224
C56.71
ICD-10 Finland
Serous epithelial malignant tumor of the ovary
17.7
14.4
22
13
C79.8
ICD-10 Finland
Secondary malignant neoplasm of other specified sites
4.7
14.3
34
77
C83.3
ICD-10 Finland
Diffuse large B-cell lymphoma
24.7
13.9
19
8
R91
ICD-10 Finland
Abnormal findings on diagnostic imaging of lung
3.0
13.9
66
241
JJ2AT
NOMESCO Finland
Biopsy of liver with ultrasound guidance
6.5
13.9
23
37
GD1AD
NOMESCO Finland
Thorax CT examination
3.8
13.9
45
129
JN6BD
NOMESCO Finland
Extensive CT of torso and neck
16.9
13.6
21
13
A04.7
ICD-10 Finland
Enterocolitis due to Clostridium difficile
5.8
13.5
25
45
I26.9
ICD-10 Finland
Pulmonary embolism without mention of acute cor pulmonale
3.8
13.4
43
122
JA3AT
NOMESCO Finland
Cathetrisation of abdominal cavity with ultrasound guidance
10.5
13.1
25
25
A06AD11
ATC
lactulose; oral
2.6
13.0
87
380
R59.0
ICD-10 Finland
Localized enlarged lymph nodes
4.9
13.0
29
62
JN4CD
NOMESCO Finland
Very extensive body CT
4.5
12.9
32
75
K70.3
ICD-10 Finland
Alcoholic cirrhosis of liver
12.8
12.7
22
18
JAL30
NOMESCO Finland
Omentectomy
13.7
12.5
21
16
JA2AT
NOMESCO Finland
Abdominal puncture with ultrasound guidance
20.8
12.5
18
9
PJD41
NOMESCO Finland
Excision of cervical lymph nodes
11.0
12.4
23
22
123
Kela drug reimbursment
Chronic disorders of vitamin D metabolism
6.0
12.4
22
38
WZC30
NOMESCO Finland
Teaching
2.4
12.3
96
450
WF002
NOMESCO Finland
Radical radiotherapy
3.6
12.2
42
125
WW409
NOMESCO Finland
Other aferesis
27.6
12.1
16
6
PJ2AT
NOMESCO Finland
Biopsy of lymphnode with ultrasound guidance
27.6
12.1
16
6
Z94.8
ICD-10 Finland
Other transplanted organ and tissue status
27.6
12.1
16
6
JN3CD
NOMESCO Finland
Abdominal CT examination both without and with contrast
4.6
12.1
29
66
L04AX01
ATC
azathioprine; systemic
4.4
12.0
31
75
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
3.0
12.0
57
208
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
2.1
11.9
151
865
C56.00
ICD-10 Finland
Malignant tumor of the ovary without histology
19.6
11.7
17
9
212
Kela drug reimbursment
Gout
9.0
11.7
24
28
C56
ICD-10 Finland
Malignant neoplasm of ovary
23.6
11.6
16
7
PH1AE
NOMESCO Finland
Ultrasound examination of upper extremity veins
9.6
11.6
23
25
K56.6
ICD-10 Finland
Other and unspecified intestinal obstruction
5.2
11.6
24
48
L01AX03
ATC
temozolomide; systemic
15.6
11.4
18
12
WF004
NOMESCO Finland
Palliative radiotherapy
8.4
11.2
24
30
182
Kela drug reimbursment
Brivaracetam, eslikarbazepin, gabapentin, lacosamide, levetiracetam, perampanel, pregabalin, tiagabin and zonisamide
5.6
11.0
21
39
D64.8
ICD-10 Finland
Other specified anaemias
9.2
10.9
22
25
YX9AD
NOMESCO Finland
Other CT eamination for dose design of radiotherapy
5.1
10.8
23
47
B01AX05
ATC
fondaparinux; parenteral
18.4
10.8
16
9
J17.3*B59
ICD-10 Finland
Pneumonia due to Pneumocystis carinii
28.8
10.8
14
5
TPH07
NOMESCO Finland
Cathetrisation of artery
2.6
10.7
68
288
JN4JR
NOMESCO Finland
Whole body extensive metabolic PET with CT
13.3
10.7
18
14
K74.6
ICD-10 Finland
Other and unspecified cirrhosis of liver
8.3
10.7
23
29
KA1AE
NOMESCO Finland
Kidney ultrasound examination
5.2
10.6
22
44
127
Kela drug reimbursment
Transplant complication
9.5
10.6
21
23
ZXE00
NOMESCO Finland
One hour or less
1.9
10.5
189
1218
AA1AD
NOMESCO Finland
CT of head and brain
2.0
10.4
138
798
8461/3-C56.9
ICD-O-3
High grade serous carcinoma of ovary
33.4
10.4
13
*
AAB10
NOMESCO Finland
Partial excision of intracranial lesion
11.7
10.1
18
16
L04AD02
ATC
tacrolimus; systemic
15.0
10.1
16
11
ZXD05
NOMESCO Finland
Urgent procedure
2.0
10.0
152
920
N18.9
ICD-10 Finland
Chronic kidney disease, unspecified
3.3
9.7
37
118
WX302
NOMESCO Finland
Thoracal epidural anesthesy
3.4
9.7
36
113
ZXE20
NOMESCO Finland
More than three and less than five hours
2.4
9.7
76
356
138
Kela drug reimbursment
Severe anaemia associated with chronic renal failure
7.4
9.6
22
31
M05BX04
ATC
denosumab; parenteral
3.3
9.6
37
119
2874X
ICD-9 Finland
Purpura and other haemorrhagic conditions, Secondary thrombocytopenia[THROMBOCYTOPENIA SECUNDARIA NUD]
+∞
9.4
9
*
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
2.2
9.3
89
453
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
2.7
9.3
52
207
J01MA02
ATC
ciprofloxacin; systemic
1.9
9.2
186
1232
C85.9
ICD-10 Finland
Non-Hodgkin lymphoma, unspecified
16.0
9.1
14
9
1XC02, ,
NOMESCO Finland
16.0
9.1
14
9
WX408
NOMESCO Finland
General anesthesy, balanced
2.0
9.0
129
761
E0000UV, ,
ATC
1.8
9.0
191
1282
KH1AE
NOMESCO Finland
Urinary tract ultrasound examination
3.2
9.0
37
124
TAB00
NOMESCO Finland
Lumbar puncture
3.4
8.9
32
98
UJF32
NOMESCO Finland
Coloscopy
1.9
8.8
132
791
ZXE30
NOMESCO Finland
More than five and less than seven hours
3.4
8.8
32
99
T88.7
ICD-10 Finland
Unspecified adverse effect of drug or medicament
7.2
8.6
20
29
ZX090
NOMESCO Finland
Other technic of radiotherapy
4.0
8.6
25
66
9673/3-C42.1
ICD-O-3
Mantle cell lymphoma of bone marrow
91.7
8.4
9
*
129
Kela drug reimbursment
Idiopathic thrombocytopaenia or granulocytopenia
+∞
8.4
8
*
AAA10
NOMESCO Finland
Biopsy through craniotomy
+∞
8.4
8
*
J05AB11
ATC
valaciclovir; oral
2.2
8.4
80
406
NK6QA
NOMESCO Finland
Measurement of bone density from two or more locations with X-ray
2.9
8.3
41
152
SPAT1148
SPAT
Treatment of chronic ulcer or burn
2.3
8.2
69
332
A41.8
ICD-10 Finland
Other specified sepsis
4.9
8.2
18
38
A06AH03
ATC
naloxegol; oral
8.4
8.2
17
21
ED1AA
NOMESCO Finland
Mandibular X-ray examination
12.0
8.1
14
12
TNE25
NOMESCO Finland
Drill biopsy of bone marrow, pelvis
9.2
8.1
16
18
9680/3-C77.9
ICD-O-3
Diffuse large B-cell lymphoma, NOS, of lymph node, NOS
22.5
8.0
11
5
B00.2
ICD-10 Finland
Herpesviral gingivostomatitis and pharyngotonsillitis
22.5
8.0
11
5
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
1.9
8.0
126
765
C10AC01
ATC
colestyramine; oral
4.6
8.0
19
43
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
2.6
7.8
48
200
A10AB05
ATC
insulin aspart; parenteral
2.6
7.8
47
194
JAH01
NOMESCO Finland
Laparoscopy
3.4
7.8
28
86
H02AB07
ATC
prednisone; oral
2.2
7.8
70
346
N18.8
ICD-10 Finland
Other chronic renal failure
6.1
7.8
20
34
A04AD12
ATC
aprepitant; systemic
4.6
7.7
18
40
ZX012
NOMESCO Finland
Radiotherapy with large shaped fields - isocentric therapy
2.9
7.6
37
136
SPAT1245
SPAT
Provision of support and information to patient’s family members
3.5
7.6
26
77
ZXC40
NOMESCO Finland
Use of ultrasound
12.1
7.6
13
11
AA1DG
NOMESCO Finland
Very extensive MRI examination of brain with high intensity magnet
4.0
7.5
21
54
WX892
NOMESCO Finland
Monitored bed care
2.6
7.5
44
179
166
Kela drug reimbursment
Dalteparin and tinzaparin (treatment for more than 6 months)
11.1
7.3
13
12
WD325
NOMESCO Finland
Demanding therapy of methastized malignancy with biomodifiers
9.6
7.3
14
15
I85.9
ICD-10 Finland
Oesophageal varices without bleeding
9.6
7.3
14
15
3009
Kela drug reimbursment
Niraparib
+∞
7.3
7
*
AA1CD
NOMESCO Finland
Very extensive CT of head and brain
6.0
7.3
19
33
R59.1
ICD-10 Finland
Generalized enlarged lymph nodes
7.5
7.2
16
22
D68.8
ICD-10 Finland
Other specified coagulation defects
20.4
7.2
10
5
C81.1
ICD-10 Finland
Nodular sclerosis classical Hodgkin lymphoma
20.4
7.2
10
5
WPA15
NOMESCO Finland
Palliative care consultation with the patient and loved ones
20.4
7.2
10
5
Z04.8
ICD-10 Finland
Examination and observation for other specified reasons
2.2
7.1
65
323
LAF16
NOMESCO Finland
Excision of uterus, adnexes and lymph nodes for treatment of ovarian cancer
12.3
7.1
12
10
N02AX02
ATC
tramadol; systemic, rectal
1.7
7.1
202
1452
FB1BD
NOMESCO Finland
Extensive CT examination of arteria pulmonalis
2.5
6.9
43
180
Z49.1
ICD-10 Finland
Extracorporeal dialysis
8.5
6.9
14
17
R11
ICD-10 Finland
Nausea and vomiting
2.4
6.8
48
213
TPH30
NOMESCO Finland
Insertion of central venous catheter through periferal vein
6.3
6.8
17
28
A07AA09
ATC
vancomycin; oral
9.5
6.8
13
14
N13.3
ICD-10 Finland
Other and unspecified hydronephrosis
4.4
6.8
17
40
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.7
6.8
188
1336
C57.9
ICD-10 Finland
Malignant neoplasm: Female genital organ, unspecified
40.7
6.8
8
*
C82.2
ICD-10 Finland
Follicular lymphoma grade III, unspecified
40.7
6.8
8
*
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
2.0
6.8
77
416
SPAT1255
SPAT
Intravenous administration of medicine
2.8
6.7
34
128
C57.0
ICD-10 Finland
Malignant neoplasm: Fallopian tube
22.9
6.7
9
*
JAH00
NOMESCO Finland
Laparotomy
3.6
6.6
22
64
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
2.2
6.6
58
283
N05BA06
ATC
lorazepam; systemic, sublingual
2.7
6.6
36
141
GA1AE
NOMESCO Finland
Ultrasound examination of thorax
4.3
6.6
17
41
PBL10
NOMESCO Finland
Construction of arteriovenous fistula from radial artery
10.2
6.6
12
12
A12AA04
ATC
calcium carbonate; oral
7.0
6.6
15
22
N05CF01
ATC
zopiclone; oral
1.7
6.5
153
1039
JN5DR
NOMESCO Finland
PET-CT of upper body metabolism
7.6
6.5
14
19
WX872
NOMESCO Finland
Intensive care
2.9
6.4
30
108
8461/3-C57.0
ICD-O-3
High grade serous carcinoma of fallopian tube
70.8
6.4
7
*
TJA10
NOMESCO Finland
Laparocentesis
70.8
6.4
7
*
TPH40
NOMESCO Finland
Insertion of a long peripheral venous catheter
14.6
6.4
10
7
OAB74
NOMESCO Finland
Nutritional guidance related to treatment and rehabilitation for medical condition
6.7
6.4
15
23
WB123
NOMESCO Finland
Demanding adjuvant cytostatic therapy
6.7
6.4
15
23
YA1BD
NOMESCO Finland
Extensive CT examination of head and neck for dose design of radiotherapy
9.4
6.3
12
13
B01AA03
ATC
warfarin; systemic
1.9
6.3
83
472
TPX15
NOMESCO Finland
Removal of vascular injection port
18.3
6.3
9
5
A07AA02
ATC
nystatin; oral
2.7
6.3
34
133
9680/3-C71.9
ICD-O-3
Diffuse large B-cell lymphoma, NOS, of brain, NOS
+∞
6.3
6
*
YNB00
NOMESCO Finland
Excision of bone marrow for transplantation
+∞
6.3
6
*
XX9CD
NOMESCO Finland
Very extensive complementary CT
+∞
6.3
6
*
M32.1
ICD-10 Finland
Systemic lupus erythematosus with organ or system involvement
+∞
6.3
6
*
Z51.3
ICD-10 Finland
Blood transfusion (without reported diagnosis)
+∞
6.3
6
*
1510
Kela drug reimbursment
Niraparib
+∞
6.3
6
*
28719
ICD-8 Finland
Purpura and other haemorrhagic conditions, Thrombocytopenia NUD
+∞
6.3
6
*
C83.9
ICD-10 Finland
Non-follicular (diffuse) lymphoma, unspecified
27.1
6.2
8
*
C71.20
ICD-10 Finland
Malignant tumor in temporal lobe without histology
27.1
6.2
8
*
EN1BD
NOMESCO Finland
Very extensive CT examination of mouth and soft tissues of neck
6.4
6.2
15
24
C90.0
ICD-10 Finland
Multiple myeloma
7.8
6.2
13
17
AA1BD
NOMESCO Finland
Extensive CT of head and brain
4.2
6.1
16
39
L04AX04
ATC
lenalidomide; oral
12.7
6.1
10
8
153
Kela drug reimbursment
Lenalidomid
12.7
6.1
10
8
WX602
NOMESCO Finland
Repeated or continuing anesthesia shots throug a catheter
2.3
6.1
47
218
M32.9
ICD-10 Finland
Systemic lupus erythematosus, unspecified
10.2
6.1
11
11
ZX080
NOMESCO Finland
Image guided radiotherapy
4.0
6.0
17
44
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
87
70
15.15
91.56
7.3
4.6
222.60
130.00
iu/ml
—
10
8
109
146
9.52
80.44
3.1
1.9
4.59
3.65
ug/l
0.13
104
133
171
395
6.36
75.61
5.0
2.3
2.03
1.79
%
1.48
166
363
144
286
6.92
74.28
6.0
2.3
80.22
70.97
e9/l
1.40
119
224
53
25
23.88
71.92
6.0
3.3
—
—
—
0
0
67
54
14.39
69.90
4.0
2.5
6455.88
697.40
u/ml
—
8
5
98
139
8.73
68.50
1.9
1.6
1.59
1.56
g/l
0.08
83
122
177
480
5.42
64.17
10.6
5.3
1.06
1.03
mmol/l
0.28
172
449
132
287
6.08
61.07
5.5
2.4
9.41
10.52
g/l
1.52
125
262
121
249
6.27
59.20
2.9
1.5
—
—
—
0
0
72
84
10.01
58.44
2.3
1.6
—
—
—
0
0
61
60
11.60
55.83
2.4
1.7
—
—
—
0
0
71
87
9.50
55.42
2.3
1.6
—
—
—
0
0
41
21
21.37
53.45
2.7
2.3
—
—
—
0
0
66
77
9.87
53.43
1.4
1.6
—
—
—
0
0
62
68
10.41
52.51
2.0
1.5
—
—
—
0
0
55
54
11.46
50.28
1.7
1.5
—
—
—
0
0
43
28
16.87
50.05
7.7
2.4
30.68
41.68
%
1.65
37
17
52
52
11.17
46.88
1.9
1.6
—
—
—
0
0
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
68
101
7.75
45.00
6.9
2.5
0.32
0.34
u/ml
0.17
42
49
310
1592
4.02
42.98
11.8
4.7
32.03
35.72
g/l
19.98
303
1499
51
57
9.96
42.40
2.1
1.5
—
—
—
0
0
64
96
7.60
41.90
4.8
2.5
88.94
89.81
%
0.09
64
91
46
49
10.34
39.54
2.0
1.5
—
—
—
0
0
64
104
7.00
38.87
2.0
1.1
—
—
—
0
0
323
1782
3.85
38.44
14.3
5.9
25.18
27.96
%
3.17
315
1676
109
293
4.58
38.03
5.4
2.8
64.13
66.84
g/l
2.90
104
271
33
23
15.40
36.86
1.3
1.2
—
—
—
0
0
48
60
8.83
36.52
2.2
1.6
—
—
—
0
0
48
60
8.83
36.52
2.2
1.6
—
—
—
0
0
161
588
3.70
36.48
2.9
1.8
—
—
—
0
0
357
2147
4.15
36.31
39.4
9.0
3.48
4.08
e9/l
5.64
338
1882
35
28
13.47
36.17
1.4
1.3
—
—
—
0
0
316
1760
3.64
36.13
13.3
5.7
57.55
57.02
%
0.26
310
1654
131
421
3.97
35.74
2.6
1.8
—
—
—
0
0
38
36
11.43
35.33
2.0
1.8
—
—
—
0
0
340
2003
3.81
35.14
22.9
6.2
12.10
11.58
umol/l
0.32
340
1901
37
34
11.76
35.09
2.3
1.6
—
—
—
0
0
37
34
11.76
35.09
2.3
1.6
—
—
—
0
0
37
34
11.76
35.09
2.3
1.6
—
—
—
0
0
311
1736
3.54
34.97
13.9
5.7
2.49
2.92
%
1.67
303
1624
39
39
10.85
34.96
1.8
1.6
—
—
—
0
0
40
42
10.35
34.65
1.9
1.7
—
—
—
0
0
128
414
3.92
34.49
2.4
1.7
—
—
—
0
0
40
43
10.11
34.06
1.8
1.6
—
—
—
0
0
40
43
10.11
34.06
1.8
1.6
—
—
—
0
0
47
63
8.21
33.73
1.2
1.2
—
—
—
0
0
316
1808
3.49
33.55
19.9
6.5
1.19
1.21
mmol/l
6.05
274
1550
44
55
8.75
33.42
1.6
1.5
96.87
98.67
u/ml
—
7
9
39
42
10.07
33.15
6.1
1.5
34.56
32.69
pg
1.36
39
42
298
1656
3.35
33.01
17.1
5.8
1.18
1.21
mmol/l
9.23
290
1520
44
56
8.60
32.93
4.7
2.9
0.90
1.02
%
0.15
39
51
46
62
8.15
32.85
1.2
1.2
281.33
224.58
u/ml
0.42
33
31
85
213
4.68
32.09
2.1
1.4
—
—
—
0
0
307
1757
3.33
31.93
19.8
11.9
1.28
1.23
inr
0.51
110
512
140
510
3.53
31.24
3.7
2.2
27.77
23.13
%
1.73
128
442
258
1354
3.11
30.86
5.3
3.1
—
—
—
0
0
108
336
3.91
30.45
7.4
3.8
2.37
2.11
mmol/l
0.29
93
273
300
1759
3.10
28.63
5.6
2.5
—
—
—
0
0
176
771
3.10
28.55
3.4
2.6
3.99
5.78
e6/l
0.92
161
691
238
1238
2.95
28.17
8.6
3.4
2.31
2.35
mmol/l
5.83
226
1101
106
346
3.70
27.67
3.7
2.3
0.18
0.22
g/l
4.35
99
325
60
130
5.17
26.78
6.8
4.5
1.76
1.34
mmol/l
1.00
60
125
34
41
8.89
26.46
2.1
1.7
—
—
—
0
0
187
894
2.86
25.30
4.9
2.2
—
—
—
0
0
206
1040
2.80
25.06
4.7
3.1
0.46
0.35
e6/l
0.31
179
774
115
428
3.26
24.16
12.7
7.6
1.34
1.16
mmol/l
0.16
97
352
216
1141
2.71
23.72
4.7
3.2
29.13
107.03
e6/l
0.74
187
868
99
353
3.31
22.17
14.1
8.4
109.43
121.58
g/l
6.38
99
345
46
93
5.39
22.10
1.9
1.3
—
—
—
0
0
53
123
4.75
21.71
2.4
2.8
—
—
—
0
0
102
376
3.21
21.58
13.8
8.0
95.29
95.80
%
0.23
102
363
175
890
2.58
20.02
2.9
2.1
3.29
3.08
mg/l
0.49
165
781
73
228
3.63
20.00
15.2
7.7
25.25
24.73
mmol/l
0.40
73
215
19
0
+∞
19.94
1.4
0.0
—
—
—
0
0
211
1187
2.46
19.25
3.9
2.5
54.59
60.22
u/l
0.62
204
1098
325
2230
2.63
19.06
13.0
4.6
6.84
6.71
mmol/l
0.53
315
2092
155
797
2.44
16.80
4.2
1.7
4.10
1.19
mg/l
2.44
136
620
38
84
4.85
16.43
1.5
1.3
—
—
—
0
0
189
1087
2.27
15.58
4.2
2.9
1422.48
989.54
ng/l
0.86
172
923
20
7
29.79
15.31
2.9
1.9
—
—
—
0
0
42
108
4.18
15.03
7.1
3.9
27.98
35.25
mg/l
0.43
31
87
42
108
4.18
15.03
7.1
3.9
56.13
112.57
mg/l
0.45
31
86
90
374
2.76
14.99
7.0
3.2
—
—
—
0
0
43
116
3.99
14.43
4.2
2.3
596.61
749.76
ug/l
0.14
38
105
27
26
10.97
14.42
2.7
2.1
545.43
507.52
e6/l
0.09
21
21
31
65
5.05
14.23
6.0
3.1
3.75
4.34
e9/l
0.50
31
65
31
66
4.97
13.98
7.7
3.6
58.32
57.70
%
0.07
31
66
94
413
2.61
13.96
3.8
4.5
16.10
23.99
ug/l
0.24
79
347
25
44
5.96
13.82
1.1
1.2
—
—
—
0
0
226
1451
2.12
13.60
5.2
3.6
30.64
64.11
ng/l
0.78
190
1027
23
19
12.69
13.24
2.0
1.6
—
—
—
0
0
326
2428
2.23
13.05
6.6
4.3
9.33
3805.23
e6/l
—
9
44
238
1575
2.08
13.03
4.0
2.6
484.29
123.14
ug/l
3.68
230
1462
41
117
3.75
12.70
3.9
1.8
0.88
0.96
g/l
0.05
32
106
153
871
2.14
12.37
1.8
1.5
18.47
21.05
nmol/l
1.45
142
736
167
985
2.10
12.29
7.4
4.0
0.00
0.00
estimate
0.50
72
332
22
20
11.50
12.16
2.1
1.6
—
—
—
0
0
23
23
10.47
12.13
2.0
1.6
—
—
—
0
0
68
272
2.77
12.07
4.8
3.9
123.59
77.83
ng/l
2.12
62
246
24
28
8.99
11.66
2.5
1.6
—
—
—
0
0
71
299
2.63
11.37
9.1
2.5
57.23
66.47
ml/min/173m2
1.13
31
127
28
67
4.39
10.97
3.3
2.4
14.95
16.45
%
0.68
17
30
128
712
2.11
10.78
2.6
1.4
2.29
2.57
g/l
0.69
108
437
119
648
2.14
10.57
4.1
2.7
1.35
0.92
e6/l
0.93
82
366
33
93
3.75
10.40
1.9
1.3
—
—
—
0
0
15
8
19.33
10.32
1.2
1.4
—
—
—
0
0
34
99
3.63
10.23
3.9
1.6
0.00
0.00
g/l
-0.00
29
93
35
104
3.56
10.22
3.9
1.6
0.00
0.00
g/l
-0.00
30
98
87
424
2.30
10.11
6.2
2.6
13.72
9.21
umol/l
1.07
81
375
257
1848
1.91
10.11
6.6
3.7
0.00
0.01
estimate
0.50
76
328
42
142
3.16
10.02
4.3
1.6
4.04
3.65
g/l
0.20
37
130
42
142
3.16
10.02
4.3
1.6
7.61
7.48
g/l
0.16
37
130
42
142
3.16
10.02
4.3
1.6
—
—
—
0
0
254
1827
1.89
9.90
8.4
4.9
0.00
0.00
estimate
0.50
79
340
32
92
3.67
9.81
1.7
1.2
583.31
460.14
mg/l
0.50
32
84
39
129
3.21
9.64
4.0
1.6
9.57
10.30
g/l
0.39
34
116
56
227
2.67
9.64
3.8
3.5
2.05
1.82
mmol/l
0.16
45
162
252
1820
1.87
9.58
6.8
3.7
0.00
0.00
estimate
0.50
78
363
191
1265
1.88
9.53
7.3
3.3
42.07
33.04
u/l
1.85
181
1204
35
111
3.33
9.26
4.2
1.5
36.04
37.57
g/l
0.85
30
99
31
92
3.54
9.07
1.3
1.3
—
—
—
0
0
31
94
3.47
8.79
1.2
1.3
—
—
—
0
0
86
441
2.17
8.77
28.5
6.9
—
—
—
0
0
38
132
3.05
8.66
4.5
1.6
3.29
3.00
g/l
0.74
33
120
20
32
6.49
8.10
6.9
1.9
—
—
—
0
0
28
84
3.49
8.07
1.8
1.2
3.74
4.01
mmol/l
0.48
28
77
20
48
4.31
7.81
1.4
1.1
—
—
—
0
0
11
6
18.74
7.63
2.1
1.0
264.55
183.67
%
—
11
6
17
26
6.75
7.18
1.4
1.4
30611.82
26049.17
e6/l
0.10
11
12
21
56
3.88
7.16
1.4
1.2
3.00
1.29
u/ml
0.59
13
14
21
58
3.75
6.83
1.5
1.2
8.00
3.78
u/ml
0.65
14
23
120
752
1.81
6.74
1.7
1.7
507.53
431.80
pmol/l
1.20
112
634
102
610
1.87
6.65
4.4
2.9
3.65
1.95
e6/l
0.99
65
331
106
644
1.84
6.57
1.9
1.7
1335.51
1231.56
nmol/l
0.47
91
498
196
1418
1.67
6.56
7.6
3.8
—
—
—
0
0
30
109
2.88
6.35
1.8
1.1
—
—
—
0
0
9
5
18.32
6.28
1.7
1.0
—
—
—
0
0
9
6
15.26
5.92
1.3
1.3
—
—
—
0
0
15
27
5.71
5.73
1.1
1.3
—
—
—
0
0
29
110
2.75
5.69
1.9
1.1
—
—
—
0
0
12
16
7.67
5.66
2.8
3.9
83.33
90.00
%
0.22
12
16
10
10
10.19
5.55
1.5
2.2
—
—
—
0
0
10
10
10.19
5.55
1.5
2.2
—
—
—
0
0
17
47
3.72
5.53
2.5
2.0
88.15
90.43
%
0.73
17
47
29
112
2.70
5.50
1.4
1.5
272.15
273.12
ug/g
0.01
20
70
12
17
7.22
5.47
1.2
1.2
—
—
—
0
0
21
68
3.19
5.41
1.4
1.4
—
—
—
0
0
29
115
2.63
5.24
1.6
1.6
0.01
0.04
iu/ml
—
8
21
326
2767
1.64
5.19
7.2
4.1
18.47
11.82
mm/h
8.95
321
2563
194
1465
1.57
5.10
2.3
1.9
89.05
95.60
pmol/l
1.41
134
751
21
71
3.05
5.05
1.4
1.4
—
—
—
0
0
21
71
3.05
5.05
1.4
1.4
—
—
—
0
0
24
88
2.82
5.02
2.7
2.0
99.85
4981.92
u/l
0.84
16
32
42
203
2.18
4.93
3.8
2.9
0.27
0.11
e6/l
0.45
42
196
8
7
11.60
4.80
1.8
1.4
—
—
—
0
0
195
1498
1.53
4.62
2.9
2.2
74.30
76.54
nmol/l
0.50
184
1333
11
19
5.91
4.46
1.0
1.2
14.36
16.21
u/l
0.20
11
19
9
12
7.63
4.37
3.7
1.8
—
—
—
0
0
9
12
7.63
4.37
3.7
1.8
—
—
—
0
0
9
13
7.04
4.18
3.7
1.8
—
—
—
0
0
343
3770
0.63
4.14
4.8
5.1
2.62
2.76
mmol/l
1.74
320
3493
14
42
3.41
4.07
3.2
2.1
—
—
—
0
0
11
22
5.10
4.02
1.5
1.9
12.27
12.65
umol/l
0.08
11
22
28
126
2.30
3.92
5.0
2.2
—
—
—
0
0
6
5
12.13
3.77
1.0
1.0
91.00
123.20
%
—
6
5
16
56
2.93
3.66
1.1
1.1
—
—
—
0
0
11
25
4.48
3.64
1.9
1.3
—
—
—
0
0
9
17
5.38
3.52
1.1
1.2
11.89
12.12
u/l
—
9
17
9
18
5.08
3.38
3.7
1.6
—
—
—
0
0
9
18
5.08
3.38
3.7
1.6
—
—
—
0
0
7
10
7.09
3.37
1.0
1.0
—
—
—
0
0
16
59
2.77
3.35
1.6
1.3
—
—
—
0
0
10
23
4.42
3.32
1.1
1.2
—
—
—
0
0
6
7
8.67
3.27
2.2
1.3
—
—
—
0
0
10
24
4.24
3.21
1.0
1.1
—
—
—
0
0
33
173
1.98
3.19
2.0
1.3
—
—
—
0
0
13
44
3.01
3.16
1.2
1.1
—
—
—
0
0
100
716
1.51
3.13
4.0
3.8
485.57
428.68
ng/l
0.11
86
567
9
20
4.57
3.13
1.3
1.4
—
—
—
0
0
341
3707
0.67
3.11
4.7
4.6
4.47
4.65
mmol/l
2.44
319
3455
21
93
2.32
3.08
1.2
1.1
—
—
—
0
0
8
16
5.07
3.06
1.3
1.1
—
—
—
0
0
12
36
3.40
3.04
1.1
1.1
—
—
—
0
0
339
3685
0.68
3.02
4.6
4.5
1.33
1.46
mmol/l
6.59
314
3410
56
354
1.66
2.97
3.2
2.3
28.85
33.86
u/l
0.81
47
296
315
3463
0.70
2.90
6.8
5.8
40.55
40.01
mmol/mol
0.43
292
3232
333
3625
0.69
2.90
5.0
4.6
6.01
5.98
mmol/l
0.16
306
3340
7
13
5.45
2.88
1.1
1.0
1663.43
1446.08
miu/ml
—
7
13
6
9
6.74
2.87
1.2
1.2
—
—
—
0
0
398
3707
1.62
2.80
51.6
13.7
28.22
23.32
mg/l
2.43
376
2914
10
28
3.63
2.80
1.1
1.0
—
—
—
0
0
5
6
8.41
2.75
1.2
1.0
—
—
—
0
0
5
6
8.41
2.75
1.2
1.0
—
—
—
0
0
7
14
5.06
2.74
2.7
1.6
54.47
64.39
ug/l
—
7
14
14
54
2.64
2.73
1.4
1.1
—
—
—
0
0
108
807
1.44
2.71
7.0
3.9
1.01
1.02
kg/l
—
9
111
9
24
3.80
2.68
1.6
1.1
—
—
—
0
0
9
24
3.80
2.68
1.6
1.1
—
—
—
0
0
10
30
3.38
2.61
1.4
1.6
—
—
—
0
0
37
216
1.78
2.61
1.4
1.2
520.20
154.91
u/ml
1.00
30
199
13
51
2.59
2.46
1.1
1.2
—
—
—
0
0
6
12
5.05
2.41
10.0
3.6
195.50
189.75
u/l
—
6
12
16
322
0.48
2.28
2.4
1.7
—
—
—
0
0
6
13
4.66
2.28
4.7
1.7
—
—
—
0
0
29
166
1.80
2.21
4.5
3.8
675.83
1590.86
u/ml
0.38
23
139
14
61
2.34
2.16
1.4
1.6
—
—
—
0
0
6
14
4.33
2.15
1.2
1.2
—
—
—
0
0
13
55
2.40
2.14
2.8
1.3
—
—
—
0
0
13
55
2.40
2.14
2.8
1.3
—
—
—
0
0
13
55
2.40
2.14
2.8
1.3
—
—
—
0
0
35
215
1.68
2.10
2.3
1.6
—
—
—
0
0
5
10
5.04
2.07
1.4
1.1
—
—
—
0
0
5
10
5.04
2.07
1.4
1.1
—
—
—
0
0
13
56
2.36
2.06
2.8
1.3
—
—
—
0
0
13
56
2.36
2.06
2.8
1.3
—
—
—
0
0
8
26
3.11
2.02
1.1
1.0
—
—
—
0
0
10
38
2.67
2.01
1.2
1.5
—
—
—
0
0
20
354
0.54
1.94
1.6
1.9
—
—
—
0
0
65
471
1.44
1.92
2.3
1.8
1.72
1.47
%
0.76
51
416
333
3563
0.75
1.88
4.4
4.1
1.44
1.30
mmol/l
2.65
310
3284
20
108
1.89
1.84
1.7
1.6
—
—
—
0
0
6
17
3.56
1.84
2.8
2.2
908.33
824.47
u/ml
—
6
17
9
35
2.60
1.81
1.1
1.1
—
—
—
0
0
7
23
3.07
1.80
1.1
1.1
—
—
—
0
0
7
23
3.07
1.80
1.7
1.1
—
—
—
0
0
7
23
3.07
1.80
1.7
1.1
—
—
—
0
0
20
109
1.87
1.80
1.3
1.2
1.46
2.94
u/ml
—
5
16
20
110
1.86
1.76
1.3
1.2
2.28
2.64
u/ml
—
5
19
5
13
3.88
1.72
1.2
1.1
—
—
—
0
0
82
1042
0.74
1.69
1.7
1.7
1.58
1.39
mmol/l
0.97
67
879
17
90
1.92
1.67
1.4
1.4
11.23
9.01
u/l
0.27
17
76
12
56
2.17
1.62
2.9
1.3
—
—
—
0
0
5
14
3.60
1.62
1.2
1.1
—
—
—
0
0
5
14
3.60
1.62
3.0
4.1
—
—
—
0
0
5
14
3.60
1.62
3.0
4.1
—
—
—
0
0
5
14
3.60
1.62
1.2
1.1
—
—
—
0
0
140
1177
1.27
1.57
3.6
3.2
6.55
7.72
mmol/l
3.03
117
984
19
319
0.58
1.56
1.6
1.8
—
—
—
0
0
8
33
2.45
1.54
1.8
1.2
—
—
—
0
0
8
33
2.45
1.54
1.6
1.2
—
—
—
0
0
8
33
2.45
1.54
1.6
1.2
—
—
—
0
0
98
791
1.31
1.50
1.2
1.3
1.22
1.62
u/ml
0.33
24
221
138
1164
1.27
1.50
4.5
3.8
25.15
7.51
mg/mmol
1.96
91
737
5
16
3.15
1.44
1.0
1.4
—
—
—
0
0
9
41
2.22
1.37
3.6
3.7
—
—
—
0
0
6
23
2.63
1.37
1.3
1.1
5.57
4.69
ug/l
—
6
18
16
90
1.81
1.34
1.4
1.3
—
—
—
0
0
5
18
2.80
1.29
1.4
1.2
—
—
—
0
0
400
4126
0.73
1.23
77.1
20.5
118.55
136.15
g/l
62.26
400
4071
5
19
2.65
1.22
1.2
1.1
10.80
35.35
u/l
—
5
19
5
19
2.65
1.22
1.2
1.1
64.20
106.06
u/l
—
5
19
5
19
2.65
1.22
2.8
1.8
60.60
49.17
umol/l
—
5
12
271
2498
1.21
1.21
5.8
3.2
90.34
51.14
u/l
4.23
260
2335
22
141
1.59
1.19
2.9
1.7
—
—
—
0
0
400
4122
0.74
1.16
77.5
20.5
35.95
40.41
%
42.49
386
3868
5
20
2.52
1.15
8.0
4.2
256.80
97.75
nmol/l
—
5
20
7
32
2.21
1.08
1.0
1.2
—
94.40
—
0
5
7
33
2.14
1.06
1.6
1.3
0.70
1.27
promille
—
7
25
15
90
1.69
1.05
1.5
1.2
36.52
32.34
u/ml
—
5
10
5
23
2.19
0.98
1.4
1.3
1.00
1.27
u/field
—
5
15
5
23
2.19
0.98
1.2
1.1
—
—
—
0
0
5
23
2.19
0.98
1.2
7.7
—
84.00
—
0
10
14
89
1.59
0.82
1.4
1.4
319.06
274.51
miu/ml
—
6
43
96
1096
0.84
0.77
3.9
4.3
20.18
20.90
%
0.17
44
503
15
99
1.53
0.76
1.3
1.3
—
—
—
0
0
9
59
1.54
0.68
1.3
1.1
—
—
—
0
0
19
136
1.41
0.68
2.0
1.6
—
—
—
0
0
69
593
1.19
0.64
1.5
1.5
—
—
—
0
0
6
101
0.59
0.63
1.2
1.4
—
—
—
0
0
70
803
0.85
0.60
2.5
3.0
0.80
0.74
ug/l
0.27
44
523
31
249
1.26
0.55
1.3
1.3
—
63.92
—
0
18
8
123
0.64
0.55
1.6
2.0
—
—
—
0
0
40
474
0.83
0.50
4.4
4.5
27.81
31.97
%
1.48
31
320
7
45
1.56
0.49
2.0
1.8
—
—
—
0
0
13
94
1.39
0.46
1.5
1.4
—
—
—
0
0
11
152
0.72
0.45
1.5
2.0
—
—
—
0
0
54
615
0.86
0.44
1.3
1.3
15.55
32.06
iu/ml
2.66
22
201
0
15
0.00
0.41
0.0
1.1
—
—
—
0
0
330
3383
0.91
0.37
5.3
4.6
2.14
1.92
mu/l
1.57
304
3092
360
3525
1.10
0.35
40.5
13.0
78.11
81.14
ml/min/173m2
1.48
340
2914
6
46
1.31
0.33
1.3
1.5
67.47
29.27
u/l
—
6
38
7
52
1.35
0.31
1.3
1.6
—
—
—
0
0
55
607
0.89
0.30
1.1
1.3
21.94
11.42
u/ml
0.32
20
237
283
2755
1.07
0.28
4.7
3.9
14.98
14.77
pmol/l
0.67
262
2495
13
103
1.27
0.28
1.7
2.4
70.14
70.49
ug/min
—
7
59
14
172
0.81
0.27
1.0
1.0
—
—
—
0
0
9
75
1.20
0.25
1.6
1.6
—
—
—
0
0
232
2257
1.06
0.22
3.2
2.8
—
—
—
0
0
0
13
0.00
0.21
0.0
1.2
—
—
—
0
0
131
1358
0.95
0.17
4.6
4.7
2.68
2.31
ug/l
0.25
119
1224
14
120
1.17
0.16
2.1
1.8
43.71
41.54
nmol/l
0.14
14
114
398
3951
1.06
0.12
57.2
16.4
88.72
77.53
umol/l
3.52
398
3951
23
250
0.92
0.11
1.1
1.2
177.24
124.41
iu/ml
0.18
11
96
11
96
1.15
0.10
1.5
1.6
251.55
278.48
mu/l
0.32
11
91
14
125
1.12
0.10
1.6
1.6
—
—
—
0
0
5
46
1.09
0.09
1.4
1.5
—
—
—
0
0
7
67
1.05
0.08
1.6
1.5
—
—
—
0
0
7
67
1.05
0.08
1.6
1.5
—
—
—
0
0
7
67
1.05
0.08
1.6
1.5
—
—
—
0
0
10
90
1.11
0.05
2.6
1.9
171.40
229.33
pmol/l
—
10
83
11
117
0.94
0.01
1.5
1.7
—
—
—
0
0
50
507
0.98
0.01
1.3
1.4
—
—
—
0
0
10
94
1.07
0.01
1.0
1.1
—
7.71
—
0
12
0
9
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.6
—
102.20
—
0
5
5
50
1.00
-0.00
1.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.8
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.7
—
—
—
0
0
5
56
0.89
-0.00
1.4
1.6
—
—
—
0
0
5
56
0.89
-0.00
1.6
1.3
6.64
7.48
mmol/l
—
5
46
Mortality – FinRegistry
↥Association
Association between endpoint D3_SCNDTHROMBOCYTOPENIA and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| D3_SCNDTHROMBOCYTOPENIA | 6.962 [5.14, 9.44] | < 0.001 |
| Birth year | 0.999 [0.99, 1.01] | 0.753 |
During the follow-up period (1.1.1998 — 31.12.2019), 515 out of 941 females with D3_SCNDTHROMBOCYTOPENIA died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| D3_SCNDTHROMBOCYTOPENIA | 6.625 [4.83, 9.08] | < 0.001 |
| Birth year | 0.987 [0.98, 1.0] | 0.008 |
During the follow-up period (1.1.1998 — 31.12.2019), 505 out of 932 males with D3_SCNDTHROMBOCYTOPENIA died.
Mortality risk
Mortality risk for people of age
years, who have D3_SCNDTHROMBOCYTOPENIA.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.688% | 0.814% |
| 5 | 4.254% | 6.786% |
| 10 | 9.942% | 17.034% |
| 15 | 19.081% | 30.032% |
| 20 | 33.067% | 46.714% |
Relationships between endpoints
↥Index endpoint: D3_SCNDTHROMBOCYTOPENIA – Secondary thrombocytopenia
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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