Diastasis of muscle

M13_DIASTASIS

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

519972

1. Apply sex-specific rule

None

519972

2. Check conditions

None

519972

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 M62.0
  • Cause of death: ICD-10 M62.0

2 out of 7 registries used, show all original rules.

334

4. Check minimum number of events

None

334

5. Include endpoints

None

334

6. Filter based on genotype QC (FinnGen only)

321

Control definitions (FinnGen only)

Control exclude
M13_SOFTTISSUE

Extra metadata

Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
M62
Name in latin
Diastasis musculi

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 1432 834 588
Only index persons 1376 813 563
Unadjusted period prevalence (%)
Whole population 0.02 0.02 0.02
Only index persons 0.03 0.03 0.02
Median age at first event (years)
Whole population 48.12 41.83 57.15
Only index persons 48.03 41.56 57.37

-FinnGen-

Key figures

All Female Male
Number of individuals 321 216 105
Unadjusted period prevalence (%) 0.07 0.08 0.05
Median age at first event (years) 49.38 43.25 61.99

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
334
Matched controls
3340
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
M62.0
ICD-10 Finland
Diastasis of muscle
4503599627370496.0
307.7
333
*
K42.9
ICD-10 Finland
Umbilical hernia without obstruction or gangrene
17.0
98.0
91
72
QBJ30
NOMESCO Finland
Correction of abdominal apron
189.1
84.5
85
6
K43.9
ICD-10 Finland
Other and unspecified ventral hernia without obstruction or gangrene
18.0
83.6
73
51
JAG96
NOMESCO Finland
Other reconstruction of abdominal wall
+∞
48.1
45
*
N02AX02
ATC
tramadol; systemic, rectal
3.5
27.5
166
743
M79.6
ICD-10 Finland
Pain in limb
3.2
23.7
148
663
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
3.1
22.6
160
766
N03AX12
ATC
[U] gabapentin; oral
4.1
21.1
66
188
JN3AD
NOMESCO Finland
Abdominal CT examination
4.4
20.4
57
149
M99.8
ICD-10 Finland
Other biomechanical lesions
212.0
19.8
20
*
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
3.1
19.7
108
441
WX402
NOMESCO Finland
General anaesthesia
3.2
19.5
103
412
E66.8
ICD-10 Finland
Other obesity
5.6
19.3
39
77
Z01.8
ICD-10 Finland
Other specified special examinations
3.1
18.0
94
371
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
3.0
17.4
100
416
M75.1
ICD-10 Finland
Rotator cuff syndrome
3.4
17.3
74
259
JAF10
NOMESCO Finland
Repair of umbilical hernia
7.3
17.2
26
38
UJF32
NOMESCO Finland
Coloscopy
3.0
16.9
95
390
M51.3
ICD-10 Finland
Other specified intervertebral disc degeneration
5.5
16.9
34
67
M54.5
ICD-10 Finland
Low back pain
2.7
16.8
142
722
N02BE01
ATC
paracetamol; systemic, rectal
6.6
16.8
317
2465
M19.0
ICD-10 Finland
Primary arthrosis of other joints
5.0
16.6
38
84
S18
ICPC
Laceration/cut
2.6
15.6
160
885
G47.3
ICD-10 Finland
Sleep apnoea
2.9
15.4
88
363
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
2.5
15.3
159
884
SPAT1249
SPAT
Treatment-related counselling outside office
2.5
15.0
158
881
QBB10
NOMESCO Finland
Major dressing of wound of skin of trunk
5.8
14.7
28
52
JN3BD
NOMESCO Finland
Extensive abdominal CT
3.9
14.2
46
133
SPAT1263
SPAT
Sampling
2.4
14.1
157
891
N03AX16
ATC
[U] pregabalin
2.9
14.1
77
308
S46.0
ICD-10 Finland
Injury of muscle(s) and tendon(s) of the rotator cuff of shoulder
5.1
14.1
31
66
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
3.6
14.0
51
160
Z71.3
ICD-10 Finland
Dietary counselling and surveillance
5.3
13.8
29
59
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
3.3
13.8
58
199
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
4.0
13.6
42
117
ZXE10
NOMESCO Finland
More than one and less than three hours
2.4
12.5
130
708
E66.01
ICD-10 Finland
Obesity due to excess calories
3.3
12.4
50
167
SPAT1153
SPAT
Removal of sutures
2.4
12.2
108
547
SPAT1144
SPAT
Treatment of reopened or infected surgical wound
4.2
12.1
34
88
N06AX21
ATC
duloxetine; oral
3.3
12.0
49
165
NBG15
NOMESCO Finland
Acromioplastia, arthroscopic
17.2
11.8
18
11
M51.1
ICD-10 Finland
Lumbar and other intervertebral disc disorders with radiculopathy
3.1
11.8
53
189
N02AJ06
ATC
codeine and paracetamol; systemic
2.3
11.7
145
845
SPAT1148
SPAT
Treatment of chronic ulcer or burn
3.3
11.7
47
156
A02BC02
ATC
pantoprazole; systemic
2.3
11.7
223
1551
SPAT1262
SPAT
Handing over of treatment supplies
2.8
11.7
68
280
K43
ICD-10 Finland
Ventral hernia
23.9
11.7
16
7
M77.1
ICD-10 Finland
Lateral epicondylitis
4.3
11.5
31
78
SPAT1310
SPAT
Counselling related to known health issue
2.3
11.1
113
604
WX000
NOMESCO Finland
Monitoring vital functions without anesthesy
4.9
11.1
25
54
L03
ICPC
Low back symptom/complaint
2.4
11.1
100
508
L08
ICPC
Shoulder symptom/complaint
2.8
11.0
64
263
R03AC02
ATC
salbutamol; inhalant
2.2
10.7
200
1358
N62
ICD-10 Finland
Hypertrophy of breast
4.7
10.7
25
56
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
3.6
10.6
37
112
Y83.8
ICD-10 Finland
Other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
5.7
10.5
20
37
M79.7
ICD-10 Finland
Fibromyalgia
12.6
10.5
18
15
SPAT1377
SPAT
Polysomnography
5.4
10.5
21
41
R51.80
ICD-10 Finland
Headache
2.7
10.4
65
277
QBE20
NOMESCO Finland
Excision and repair of scar or web of skin of trunk
24.3
10.3
14
6
NA3BG
NOMESCO Finland
Lumbar spine MRI examination with high intensity magnet
3.7
10.3
34
99
WYA05
NOMESCO Finland
Emergency visit or other similar visit involving procedures
2.1
10.2
171
1108
M25.5
ICD-10 Finland
Pain in joint
2.2
10.2
109
593
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
2.1
10.0
149
920
K42
ICD-10 Finland
Umbilical hernia
12.7
10.0
17
14
O30.0
ICD-10 Finland
Twin pregnancy
9.2
9.9
20
23
O82.0
ICD-10 Finland
Delivery by elective caesarean section
3.6
9.9
34
102
J01DB01
ATC
cefalexin; oral
2.7
9.9
286
2291
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
3.2
9.8
42
145
JAD30
NOMESCO Finland
Repair of incisional hernia using prosthetic material
13.9
9.8
16
12
JAG60
NOMESCO Finland
Reconstruction of abdominal wall using prosthetic material
56.7
9.7
11
*
R10.1
ICD-10 Finland
Pain localized to upper abdomen
2.5
9.6
70
321
H02AB06
ATC
prednisolone; systemic
2.1
9.5
151
951
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
2.4
9.5
74
350
M62.1
ICD-10 Finland
Other rupture of muscle (nontraumatic)
102.8
9.5
10
*
N02BF01
ATC
gabapentin; oral
3.8
9.5
30
85
A02BC05
ATC
esomeprazole; systemic
2.1
9.4
133
801
JDF11
NOMESCO Finland
Laparoscopic gastric bypass
11.1
9.4
17
16
B01AB05
ATC
enoxaparin; parenteral
2.2
9.3
103
564
M79.1
ICD-10 Finland
Myalgia
2.7
9.3
53
215
O63.0
ICD-10 Finland
Prolonged first stage (of labour)
4.6
9.2
22
50
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
2.7
9.2
52
210
SPAT1058
SPAT
PEF monitoring instruction
3.5
9.2
32
97
J01FF01
ATC
clindamycin; systemic
2.2
9.1
92
485
T81.0
ICD-10 Finland
Haemorrhage and haematoma complicating a procedure, not elsewhere classified
3.8
9.0
28
78
T90
ICPC
Diabetes non-insulin dependent
2.4
9.0
75
365
M79.0
ICD-10 Finland
Rheumatism, unspecified
24.8
9.0
12
5
SPAT1312
SPAT
General health counselling
2.1
8.9
115
667
SAA01
NOMESCO Finland
Simple examination of mouth
2.2
8.9
254
1964
O34.2
ICD-10 Finland
Maternal care due to uterine scar from previous surgery
3.0
8.8
42
154
NDM20
NOMESCO Finland
Excision of synovial ganglion of wrist or hand
51.4
8.7
10
*
M70.6
ICD-10 Finland
Trochanteric bursitis
3.3
8.7
35
116
SPAT1301
SPAT
No procedures
2.1
8.6
104
587
K21.9
ICD-10 Finland
Gastro-oesophageal reflux disease without oesophagitis
3.0
8.6
39
139
MCA10
NOMESCO Finland
Lower uterine segment caesarean section
2.4
8.6
68
323
L28
ICPC
Limited function/disability (L)
2.7
8.5
49
199
K45.8
ICD-10 Finland
Other specified abdominal hernia without obstruction or gangrene
28.3
8.5
11
*
T82
ICPC
Obesity
4.5
8.5
21
49
SPAT1211
SPAT
Application of soft bandage
3.4
8.5
32
102
L57.4
ICD-10 Finland
Cutis laxa senilis
92.3
8.5
9
*
NDM40
NOMESCO Finland
Discission of sheath of tendon of wrist or hand
92.3
8.5
9
*
WX320
NOMESCO Finland
Spinalanesthesy
2.2
8.2
86
458
S97
ICPC
Chronic ulcer skin
4.0
8.2
24
64
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
2.2
8.2
78
400
R4110, ,
SPAT
3.3
8.2
31
99
HAD30
NOMESCO Finland
Reduction mammoplasty with transposition of areola
4.5
8.1
20
47
S04
ICPC
Lump/swelling localized
2.9
8.0
39
145
G56.0
ICD-10 Finland
Carpal tunnel syndrome
2.8
8.0
43
169
WX408
NOMESCO Finland
General anesthesy, balanced
2.1
7.9
90
495
Z01.2
ICD-10 Finland
Dental examination
1.9
7.9
157
1052
M77.4
ICD-10 Finland
Metatarsalgia
4.1
7.8
22
57
A10BA02
ATC
metformin; oral
2.1
7.8
90
498
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.9
7.5
129
820
JAF30
NOMESCO Finland
Repair of umbilical hernia using prosthetic material
7.9
7.5
16
21
M65.3
ICD-10 Finland
Trigger finger
7.9
7.5
16
21
WX404
NOMESCO Finland
Intravenous generell anesthesy
2.2
7.5
75
392
205
Kela drug reimbursment
Chronic hypertension
2.3
7.4
65
321
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
2.1
7.4
90
506
J02AC01
ATC
fluconazole; systemic
1.9
7.3
150
1010
JAF11
NOMESCO Finland
Laparoscopic repair of umbilical hernia
20.5
7.2
10
5
K21.0
ICD-10 Finland
Gastro-oesophageal reflux disease with oesophagitis
2.9
7.1
34
125
J01AA02
ATC
doxycycline; systemic
2.0
7.0
249
1985
K07.60
ICD-10 Finland
Snapping jaw
3.4
6.8
25
78
SPAT1254
SPAT
Administration of medicine
2.5
6.8
43
183
I10
ICD-10 Finland
Essential (primary) hypertension
1.8
6.8
159
1108
WZB00, ,
SPAT
2.9
6.8
32
117
O24.4
ICD-10 Finland
Diabetes mellitus arising in pregnancy
2.3
6.8
55
263
F43.22
ICD-10 Finland
Adaptation disorder with mixed anxiety and depression
3.3
6.7
25
79
E11.9
ICD-10 Finland
Type 2 diabetes mellitus, without complications
2.1
6.7
69
364
SHB00
NOMESCO Finland
Preparing and fitting the occlusal splint in the mouth
2.3
6.6
53
252
WZC00
NOMESCO Finland
Treatment plan or consultation
1.9
6.6
114
721
M54.4
ICD-10 Finland
Lumbago with sciatica
2.3
6.6
56
273
SPAT1250
SPAT
Comprehensive monitoring of chronic illness
2.1
6.6
71
381
D01AC20
ATC
imidazoles/triazoles in combination with corticosteroids; topical
2.1
6.6
73
396
E66.9
ICD-10 Finland
Obesity, unspecified
3.7
6.5
21
60
SFA20
NOMESCO Finland
Two-surface restoration
1.8
6.5
204
1544
P06
ICPC
Sleep disturbance
2.5
6.5
43
187
215
Kela drug reimbursment
Diabetes, non-insulin-treated
2.1
6.5
74
405
SFA10
NOMESCO Finland
One-surface restoration
1.8
6.5
189
1400
WZC00, ,
SPAT
2.8
6.4
34
132
X59
ICD-10 Finland
Exposure to unspecified factor
2.2
6.4
60
304
N06AX12
ATC
bupropion; oral
2.7
6.3
34
133
M79.5
ICD-10 Finland
Residual foreign body in soft tissue
9.5
6.3
12
13
XA402
NOMESCO Finland
ENMG
9.5
6.3
12
13
N39.4
ICD-10 Finland
Other specified urinary incontinence
3.1
6.3
27
93
M01AH01
ATC
celecoxib; oral
2.4
6.3
47
216
ACC51
NOMESCO Finland
Release of median nerve
3.3
6.3
24
77
C10AX09
ATC
ezetimibe; oral
2.4
6.3
43
190
SPAT1229
SPAT
Assessment of need for aid
3.7
6.3
20
57
O64.0
ICD-10 Finland
Obstructed labour due to incomplete rotation of fetal head
4.1
6.2
17
43
M01AE02
ATC
naproxen; oral, rectal
1.8
6.2
185
1371
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.8
6.2
176
1286
J01FA10
ATC
azithromycin; systemic
1.8
6.2
197
1488
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
2.6
6.2
37
153
NBL00
NOMESCO Finland
Suture or reinsertation of rotator cuff of shoulder
7.9
6.2
13
17
N06AX16
ATC
venlafaxine; oral
2.2
6.2
53
259
I49.3
ICD-10 Finland
Ventricular premature depolarization
3.1
6.1
26
89
SPAT1306
SPAT
Counselling and guidance related to nutrition and weight management
2.3
6.1
49
232
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
2.0
6.1
79
452
SPAT1256
SPAT
Intramuscular and subcutaneous injection
1.8
6.1
125
830
T81.3
ICD-10 Finland
Disruption of operation wound, not elsewhere classified
6.2
6.1
15
25
G44.2
ICD-10 Finland
Tension-type headache
2.2
6.0
51
248

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
181
956
2.95
21.00
15.9
11.3
1.21
1.20
inr
0.03
72
315
146
702
2.92
19.92
3.0
2.1
56.57
65.14
u/l
0.54
133
658
209
1271
2.72
17.30
2.8
2.5
—
—
—
0
0
130
646
2.66
15.94
5.0
3.5
0.00
0.00
estimate
0.50
50
242
193
1175
2.52
15.22
5.7
6.4
10.61
11.26
umol/l
0.50
181
1113
23
37
6.60
13.93
2.9
2.9
3.37
2.35
mmol/l
0.48
12
24
116
584
2.51
13.46
3.1
2.0
2.97
2.85
mg/l
0.30
101
507
211
1389
2.41
13.29
5.4
4.6
6.61
6.56
mmol/l
0.12
189
1254
198
1268
2.38
13.28
5.7
4.3
0.00
0.00
estimate
0.50
52
250
197
1259
2.38
13.28
4.6
3.1
0.00
0.00
estimate
0.50
55
259
198
1280
2.34
12.83
4.6
3.1
0.00
0.00
estimate
-0.00
53
238
22
38
6.13
12.43
2.4
2.7
—
—
—
0
0
98
478
2.49
11.98
2.1
1.6
434.43
16046928.69
pmol/l
0.50
80
430
59
222
3.01
11.95
4.8
3.1
—
—
—
0
0
156
940
2.24
11.61
4.8
4.8
36.08
36.15
g/l
0.06
144
879
246
1789
2.42
11.54
4.7
3.6
—
—
—
0
0
67
280
2.74
11.16
1.6
1.5
—
—
—
0
0
111
604
2.25
10.37
3.7
3.2
—
—
—
0
0
136
804
2.17
10.33
4.3
3.2
39.54
36.76
ng/l
0.05
86
483
251
1885
2.33
10.24
7.6
6.8
73.00
76.71
u/l
0.89
242
1773
245
1824
2.29
10.17
4.0
3.4
10.44
10.58
mm/h
0.06
232
1683
161
1021
2.11
10.14
3.8
2.9
5.94
5.85
ph
—
8
105
68
300
2.59
10.12
2.3
2.1
—
—
—
0
0
118
666
2.19
10.02
3.2
3.0
8.33
8.08
mmol/l
0.24
103
583
315
2677
4.11
9.45
17.9
12.1
139.65
139.62
mmol/l
0.09
309
2600
315
2686
4.04
9.20
17.7
12.1
3.94
3.93
mmol/l
0.17
309
2602
266
2093
2.33
9.00
4.9
3.9
14.60
14.43
pmol/l
0.55
241
1928
110
626
2.13
8.99
4.1
3.8
3.20
8.68
mg/mmol
2.28
66
419
315
2696
3.96
8.93
15.6
11.0
20.86
22.29
mg/l
0.31
269
2063
73
355
2.35
8.73
2.1
1.6
1452.41
1163.40
nmol/l
1.32
55
269
64
294
2.46
8.68
1.3
1.2
—
—
—
0
0
180
1237
1.99
8.64
4.3
5.5
0.55
0.55
e9/l
0.12
165
1084
87
460
2.21
8.51
2.7
2.5
6.71
7.37
e6/l
0.11
80
409
106
606
2.10
8.49
1.3
1.2
4.65
2.03
u/ml
0.45
41
172
173
1178
1.97
8.47
6.0
5.9
—
—
—
0
0
103
585
2.10
8.38
3.5
3.3
24.48
269.52
mg/l
0.98
60
407
63
292
2.43
8.36
2.1
2.4
27.34
23.84
%
0.78
54
256
179
1239
1.96
8.30
4.3
5.5
0.04
0.04
e9/l
0.27
165
1086
94
519
2.13
8.21
1.8
1.4
22.09
20.75
nmol/l
0.33
83
448
78
400
2.24
8.20
1.9
2.0
—
—
—
0
0
96
536
2.11
8.14
4.8
3.4
1.01
1.02
kg/l
0.70
15
74
201
1462
1.94
7.89
5.1
9.0
4.18
4.09
e9/l
0.24
187
1275
190
1358
1.93
7.84
3.5
2.7
93.26
88.40
ug/l
0.18
177
1273
182
1284
1.92
7.80
4.3
5.9
0.18
0.18
e9/l
0.08
166
1138
181
1281
1.90
7.62
4.4
5.4
1.91
1.92
e9/l
0.03
169
1147
121
751
1.96
7.57
3.9
2.8
—
—
—
0
0
19
33
6.04
7.33
2.1
2.4
17.00
17.48
%
—
9
18
156
1063
1.88
7.29
5.6
6.9
1.20
1.21
mmol/l
0.54
123
911
130
847
1.88
6.90
2.4
2.1
—
—
—
0
0
132
865
1.87
6.87
2.3
1.8
95.41
93.73
pmol/l
0.15
73
475
68
356
2.14
6.70
2.1
2.2
14.17
13.96
umol/l
0.08
63
334
80
446
2.04
6.68
2.6
2.8
558.72
565.50
mosm/kgh2o
0.10
74
379
35
137
2.74
6.53
1.3
1.2
—
—
—
0
0
110
693
1.88
6.40
2.7
2.4
—
—
—
0
0
158
1116
1.79
6.30
4.4
5.5
0.65
0.67
%
0.19
149
1046
293
2516
2.34
6.29
5.6
4.5
1.72
1.80
mu/l
0.78
269
2340
164
1174
1.78
6.23
4.8
5.7
7.99
8.26
%
0.64
157
1110
91
546
1.92
6.11
4.2
4.0
—
—
—
0
0
16
40
4.15
5.97
2.8
2.5
4.79
4.36
e9/l
0.29
16
40
116
758
1.81
5.93
2.3
3.4
2.33
2.35
mmol/l
1.04
109
688
162
1168
1.75
5.90
4.5
5.4
2.67
2.65
%
0.04
153
1102
279
2370
2.08
5.85
6.7
4.6
39.06
38.44
mmol/mol
0.61
269
2239
13
19
7.07
5.79
1.2
1.9
89.68
89.53
%
0.03
13
19
322
2919
3.87
5.76
18.9
10.5
—
—
—
0
0
217
1707
1.77
5.75
4.5
3.2
—
—
—
0
0
87
525
1.89
5.70
1.7
1.6
0.95
1.03
mg/l
0.21
65
395
167
1223
1.73
5.69
4.6
5.4
28.32
28.69
%
0.18
160
1163
95
590
1.85
5.69
1.7
2.0
123.07
241.80
u/l
1.57
86
551
158
1142
1.73
5.63
10.3
8.4
0.00
0.00
e9/l
0.54
140
949
16
42
3.95
5.60
2.8
2.6
66.44
57.90
%
2.04
16
42
137
953
1.74
5.58
5.8
6.3
1.20
1.21
mmol/l
0.77
132
878
74
427
1.94
5.53
1.5
1.2
31.09
31.48
iu/ml
0.01
23
133
293
2562
2.17
5.26
5.2
3.7
5.89
5.76
mmol/l
1.19
275
2371
163
1204
1.69
5.25
4.2
5.3
57.65
57.20
%
0.20
155
1142
100
646
1.78
5.21
3.1
3.9
7.39
7.40
ph
0.61
35
119
132
928
1.70
5.07
1.6
1.6
—
—
—
0
0
86
548
1.77
4.63
4.7
3.1
—
—
—
0
0
20
70
2.98
4.58
1.9
1.4
36.60
39.57
nmol/l
0.24
20
70
93
618
1.70
4.29
2.8
2.7
—
—
—
0
0
43
224
2.06
4.25
1.3
1.3
126.05
183.47
iu/ml
0.46
19
99
102
697
1.67
4.23
2.8
2.9
27.61
148.62
e6/l
0.69
91
523
225
1864
1.63
4.21
4.1
2.8
44.09
42.63
u/l
0.13
212
1780
46
247
2.00
4.19
1.3
1.3
—
—
—
0
0
93
623
1.68
4.15
2.8
2.7
0.15
0.39
e6/l
2.49
83
458
118
847
1.61
3.99
3.0
3.3
108.95
59.71
e6/l
0.41
99
564
315
2900
2.52
3.94
11.7
8.5
25.62
25.55
u/l
0.03
307
2815
85
564
1.68
3.91
2.5
2.5
346.09
8062.57
umol/l
2.86
76
508
85
569
1.66
3.77
1.3
1.4
2.37
2.27
g/l
0.17
58
369
141
1067
1.56
3.75
2.0
2.0
—
—
—
0
0
32
158
2.13
3.64
3.3
4.2
0.17
0.18
%
—
6
44
32
158
2.13
3.64
3.8
3.5
—
—
—
0
0
62
387
1.74
3.54
1.5
1.2
3.33
9.44
u/ml
0.93
25
161
32
160
2.11
3.53
3.3
4.0
1.43
0.81
%
—
7
51
19
75
2.63
3.53
9.9
4.7
—
—
—
0
0
294
2661
1.88
3.49
5.0
3.7
1.42
1.47
mmol/l
1.58
276
2505
298
2710
1.92
3.47
5.4
4.0
2.78
2.81
mmol/l
0.27
280
2550
27
127
2.23
3.46
2.2
5.2
7.39
7.41
ph
—
8
15
54
327
1.78
3.42
1.4
1.3
306.67
455.48
titre
—
6
62
13
42
3.18
3.41
3.4
3.2
—
—
—
0
0
9
18
5.11
3.39
1.4
1.3
5.16
6.83
mmol/l
—
9
18
7
10
7.12
3.38
1.0
1.0
—
—
—
0
0
13
43
3.11
3.28
2.2
2.2
—
—
—
0
0
35
188
1.96
3.20
1.9
2.1
12342.14
2537.08
u/l
—
10
86
7
11
6.47
3.20
1.0
1.0
—
—
—
0
0
293
2674
1.78
3.04
5.1
3.7
4.65
4.70
mmol/l
0.37
276
2526
31
168
1.93
2.78
3.4
4.0
0.00
0.12
%
—
5
50
29
155
1.95
2.71
2.3
2.5
76.54
69.95
e9/l
0.63
22
113
8
19
4.29
2.69
1.5
1.2
—
—
—
0
0
29
156
1.94
2.66
2.7
2.3
4.06
8.82
ug/l
1.49
29
139
14
55
2.61
2.65
1.8
1.3
309.44
330.37
ug/g
—
9
28
21
100
2.17
2.65
2.8
2.9
0.74
0.64
%
0.54
21
100
282
2571
1.62
2.64
4.5
3.4
1.30
1.24
mmol/l
0.84
267
2414
22
107
2.13
2.64
1.1
1.0
—
—
—
0
0
21
101
2.15
2.59
2.8
3.0
1.25
1.17
%
0.17
21
101
28
153
1.91
2.47
1.4
1.2
—
—
—
0
0
32
184
1.82
2.42
3.3
3.9
0.83
1.27
%
—
6
66
23
118
2.02
2.42
8.4
4.4
—
—
—
0
0
58
393
1.58
2.41
2.1
2.6
2.43
2.43
mmol/l
0.07
50
344
31
177
1.83
2.40
2.8
3.8
2.42
1.64
mmol/l
0.65
25
138
5
8
6.32
2.38
1.0
1.1
—
—
—
0
0
41
256
1.69
2.35
3.1
2.6
11.90
7.36
umol/l
0.47
35
219
22
113
2.01
2.31
15.5
7.5
24.68
24.12
mmol/l
0.26
22
106
20
99
2.09
2.31
2.5
2.2
—
—
—
0
0
43
275
1.65
2.26
1.5
1.4
—
—
—
0
0
15
67
2.30
2.21
2.1
4.4
0.27
0.22
g/l
—
10
34
8
24
3.39
2.19
2.8
3.0
—
—
—
0
0
8
25
3.25
2.11
4.1
3.0
—
—
—
0
0
18
89
2.08
2.10
1.8
1.7
—
—
—
0
0
10
37
2.75
2.08
1.1
1.3
—
—
—
0
0
5
10
5.06
2.08
4.2
2.7
33660.00
31590.50
ug/l
—
5
10
30
178
1.75
2.07
2.9
3.8
5.72
5.68
kpa
0.09
30
172
6
15
4.05
2.05
1.0
1.1
—
—
—
0
0
14
63
2.28
2.04
1.0
1.1
—
—
—
0
0
22
119
1.91
2.02
11.6
12.0
93.60
93.86
%
0.11
22
119
140
1158
1.36
2.01
3.1
2.5
—
—
—
0
0
36
227
1.66
2.01
1.3
1.2
—
—
—
0
0
16
77
2.13
2.00
1.1
1.1
—
—
—
0
0
26
151
1.78
1.93
2.8
3.2
4.62
4.75
kpa
0.14
26
145
6
17
3.57
1.84
1.2
2.6
12.28
14.84
ug/l
—
6
17
6
17
3.57
1.84
4.5
2.1
78.25
14.22
mu/l
—
6
17
9
35
2.61
1.81
3.0
1.9
13.24
13.07
%
—
9
35
19
103
1.90
1.75
1.1
1.1
—
—
—
0
0
10
42
2.42
1.63
1.3
1.1
—
—
—
0
0
5
14
3.61
1.62
1.0
1.1
—
—
—
0
0
8
32
2.54
1.60
1.3
1.2
—
—
—
0
0
83
653
1.36
1.60
1.8
1.7
—
—
—
0
0
81
636
1.36
1.58
1.9
1.6
1.48
1.40
mmol/l
0.32
65
547
36
243
1.54
1.55
8.9
7.4
104.36
104.65
mmol/l
0.15
36
243
6
21
2.89
1.51
3.3
1.2
—
—
—
0
0
53
390
1.43
1.51
3.0
3.4
326.66
347.05
ng/l
0.03
32
269
26
397
0.63
1.50
1.2
1.4
—
—
—
0
0
19
109
1.79
1.50
1.6
1.4
—
—
—
0
0
16
87
1.88
1.48
1.3
1.7
—
—
—
0
0
265
2467
1.36
1.47
15.5
13.4
14.81
14.33
%
0.64
259
2424
5
16
3.16
1.44
1.0
1.0
—
—
—
0
0
16
89
1.84
1.39
1.3
1.1
—
—
—
0
0
6
23
2.64
1.37
3.3
4.2
2.38
3.27
nmol/l
—
6
23
13
68
1.95
1.35
3.0
2.9
—
—
—
0
0
77
615
1.33
1.34
3.3
6.6
—
—
—
0
0
83
671
1.32
1.32
5.3
4.6
1.81
2.65
ug/l
0.87
78
604
19
114
1.71
1.31
2.4
3.4
—
—
—
0
0
5
18
2.80
1.29
1.6
1.3
—
—
—
0
0
5
18
2.80
1.29
2.2
2.5
—
—
—
0
0
28
187
1.54
1.29
3.3
4.5
—
—
—
0
0
45
332
1.41
1.27
1.3
1.2
—
—
—
0
0
17
100
1.74
1.26
1.1
1.2
—
—
—
0
0
6
25
2.42
1.25
1.0
1.1
—
—
—
0
0
9
45
2.03
1.24
1.1
1.0
—
—
—
0
0
8
37
2.19
1.22
1.1
1.0
—
—
—
0
0
22
142
1.59
1.17
3.2
2.6
—
—
—
0
0
32
225
1.47
1.17
1.9
2.7
1.85
1.79
%
0.17
27
204
21
134
1.61
1.17
1.7
1.5
—
—
—
0
0
20
126
1.62
1.17
1.7
1.5
—
—
—
0
0
8
39
2.08
1.16
1.0
1.4
—
—
—
0
0
5
20
2.52
1.15
1.2
1.2
—
—
—
0
0
48
365
1.37
1.15
1.9
1.6
—
—
—
0
0
21
135
1.59
1.14
1.7
1.5
—
—
—
0
0
21
136
1.58
1.11
1.7
1.5
—
—
—
0
0
21
136
1.58
1.11
1.7
1.5
—
—
—
0
0
5
21
2.40
1.09
1.0
1.3
—
—
—
0
0
13
75
1.76
1.04
2.2
2.2
4.61
1.36
ug/l
0.40
13
68
15
91
1.68
1.02
2.5
1.9
—
—
—
0
0
11
62
1.80
0.95
2.2
4.5
—
—
—
0
0
23
160
1.47
0.91
1.6
1.4
—
—
—
0
0
11
63
1.77
0.91
1.9
1.2
—
—
—
0
0
6
29
2.09
0.89
1.3
3.0
108.83
105.00
mmol/l
—
6
29
6
29
2.09
0.89
1.3
3.0
—
—
—
0
0
6
29
2.09
0.89
1.3
3.0
3.88
3.98
mmol/l
—
6
29
14
87
1.64
0.89
2.1
6.0
—
—
—
0
0
13
80
1.65
0.86
2.2
1.4
1.28
1.19
g/l
0.44
13
75
18
121
1.52
0.84
1.6
1.4
106.66
261.24
miu/ml
—
7
62
12
73
1.67
0.82
2.4
7.2
24.50
24.99
mmol/l
0.31
12
73
0
25
0.00
0.79
0.0
14.9
—
945.88
—
0
25
0
26
0.00
0.78
0.0
20.6
—
1694.19
—
0
26
35
271
1.33
0.78
1.3
1.3
—
—
—
0
0
5
24
2.10
0.75
1.8
2.0
—
—
—
0
0
89
780
1.19
0.70
1.8
1.9
—
—
—
0
0
10
62
1.63
0.66
3.3
6.0
0.80
0.86
%
—
10
56
7
44
1.60
0.65
1.0
1.3
—
—
—
0
0
8
50
1.61
0.61
1.9
2.8
—
—
—
0
0
8
51
1.58
0.61
1.0
1.6
—
—
—
0
0
8
52
1.55
0.60
2.4
2.1
—
—
—
0
0
9
60
1.51
0.55
1.2
1.5
—
—
—
0
0
10
66
1.53
0.53
3.3
5.6
1.54
1.80
%
—
10
59
22
171
1.31
0.51
7.8
10.2
—
—
—
0
0
12
85
1.43
0.47
2.7
2.0
2.92
6.45
iu/l
—
5
36
61
537
1.17
0.47
1.7
1.6
—
—
—
0
0
43
367
1.20
0.47
1.5
1.4
—
—
—
0
0
0
16
0.00
0.41
0.0
1.6
—
—
—
0
0
0
17
0.00
0.41
0.0
1.1
—
77.53
—
0
17
0
18
0.00
0.40
0.0
3.2
—
12.43
—
0
18
0
19
0.00
0.39
0.0
1.5
—
1.50
—
0
19
13
169
0.76
0.38
1.5
1.4
—
—
—
0
0
13
169
0.76
0.38
1.5
1.4
—
—
—
0
0
14
110
1.28
0.32
1.1
1.2
—
—
—
0
0
14
174
0.80
0.30
1.6
1.4
—
—
—
0
0
11
84
1.32
0.30
11.4
6.3
—
—
—
0
0
25
216
1.17
0.26
1.4
1.4
—
—
—
0
0
21
244
0.85
0.25
1.3
1.4
—
—
—
0
0
5
38
1.32
0.23
3.8
2.8
—
—
—
0
0
5
42
1.19
0.21
1.0
1.1
—
—
—
0
0
0
11
0.00
0.21
0.0
1.3
—
—
—
0
0
0
10
0.00
0.21
0.0
1.6
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
3.94
—
0
10
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
12
0.00
0.21
0.0
1.0
—
—
—
0
0
0
12
0.00
0.21
0.0
2.3
—
—
—
0
0
5
43
1.17
0.21
1.2
1.1
—
—
—
0
0
0
14
0.00
0.20
0.0
2.3
—
—
—
0
0
12
101
1.20
0.17
11.1
12.2
—
—
—
0
0
8
69
1.16
0.16
1.3
1.1
—
—
—
0
0
33
359
0.91
0.16
2.2
2.5
3.42
3.05
e6/l
0.09
19
196
8
73
1.10
0.16
1.1
1.1
—
—
—
0
0
5
48
1.04
0.09
1.4
1.3
—
—
—
0
0
5
60
0.83
0.08
1.0
1.1
—
—
—
0
0
5
60
0.83
0.08
1.0
1.1
—
—
—
0
0
5
62
0.80
0.08
1.0
1.2
—
4.86
—
0
10
5
62
0.80
0.08
1.8
2.9
—
—
—
0
0
6
71
0.84
0.07
1.8
1.7
—
—
—
0
0
22
235
0.93
0.07
1.4
1.7
—
—
—
0
0
10
91
1.10
0.04
4.1
3.7
25.99
23.80
mmol/l
—
10
91
12
111
1.08
0.04
1.1
2.9
—
—
—
0
0
23
237
0.97
0.01
1.8
1.5
—
—
—
0
0
13
124
1.05
0.00
1.2
1.1
—
—
—
0
0
40
395
1.01
0.00
3.2
2.9
0.58
0.76
ug/l
1.16
29
259
0
5
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
151.38
—
0
8
0
9
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.5
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.5
—
—
—
0
0
0
5
0.00
-0.00
0.0
3.4
—
—
—
0
0
0
5
0.00
-0.00
0.0
2.6
—
2.79
—
0
5
0
5
0.00
-0.00
0.0
3.4
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
2.7
—
4.85
—
0
6
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
2.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
6
0.00
-0.00
0.0
2.7
—
2.45
—
0
6
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
8
0.00
-0.00
0.0
2.6
—
1.16
—
0
8
0
9
0.00
-0.00
0.0
3.4
—
6.96
—
0
9

Mortality – FinRegistry

Association

Association between endpoint M13_DIASTASIS and mortality.

Females

No data

Males

Parameter HR [95% CI] p-value
M13_DIASTASIS 0.982 [0.75, 1.28] 0.891
Birth year 0.99 [0.98, 1.0] 0.051

During the follow-up period (1.1.1998 — 31.12.2019), 73 out of 493 males with M13_DIASTASIS died.

Mortality risk

Mortality risk for people of age

years, who have M13_DIASTASIS.

N-year risk Females Males
1 No data 0.197%
5 No data 1.252%
10 No data 3.111%
15 No data 5.867%
20 No data 10.226%

Relationships between endpoints

Index endpoint: M13_DIASTASIS – Diastasis of muscle

GWS hits: 2

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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