Diastasis of muscle

M13_DIASTASIS

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 M62.0
  • Cause of death: ICD-10 M62.0

2 out of 7 registries used, show all original rules.

278

4. Check minimum number of events

None

278

5. Include endpoints

None

278

6. Filter based on genotype QC (FinnGen only)

278

Control definitions (FinnGen only)

Control exclude
M13_SOFTTISSUE

Extra metadata

Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
M62
Name in latin
Diastasis musculi

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 1432 834 588
Only index persons 1376 813 563
Unadjusted period prevalence (%)
Whole population 0.02 0.02 0.02
Only index persons 0.03 0.03 0.02
Median age at first event (years)
Whole population 48.12 41.83 57.15
Only index persons 48.03 41.56 57.37

-FinnGen-

Key figures

All Female Male
Number of individuals 278 183 95
Unadjusted period prevalence (%) 0.06 0.06 0.04
Median age at first event (years) 49.47 43.45 61.05

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
237
Matched controls
2371
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
M62.0
ICD-10 Finland
Diastasis of muscle
+∞
323.0
237
*
QBJ30
NOMESCO Finland
Correction of abdominal apron
674.1
56.0
53
*
K42.9
ICD-10 Finland
Umbilical hernia without obstruction or gangrene
21.6
38.8
58
35
K43.9
ICD-10 Finland
Other and unspecified ventral hernia without obstruction or gangrene
17.0
28.6
46
33
JAG96
NOMESCO Finland
Other reconstruction of abdominal wall
253.5
23.0
23
*
N02AX02
ATC
tramadol; systemic, rectal
3.8
20.6
122
514
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
3.3
16.0
113
515
M79.6
ICD-10 Finland
Pain in limb
3.8
15.9
81
286
N02BE01
ATC
paracetamol; systemic, rectal
4.7
14.9
216
1622
N03AX12
ATC
gabapentin; oral
5.0
13.4
45
106
JN3AD
NOMESCO Finland
Abdominal CT examination
6.4
12.8
34
60
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
3.1
11.6
76
314
S18
ICPC
Laceration/cut
2.7
11.1
100
505
A02BC02
ATC
pantoprazole; systemic
2.6
10.8
154
995
M19.0
ICD-10 Finland
Primary arthrosis of other joints
6.5
10.5
27
46
M54.5
ICD-10 Finland
Low back pain
2.7
10.4
91
447
NBG15
NOMESCO Finland
Acromioplastia, arthroscopic
42.0
10.1
12
*
JAF10
NOMESCO Finland
Repair of umbilical hernia
11.4
10.0
18
17
JAG60
NOMESCO Finland
Reconstruction of abdominal wall using prosthetic material
104.0
9.5
10
*
O30.0
ICD-10 Finland
Twin pregnancy
10.2
9.4
18
19
JN3BD
NOMESCO Finland
Extensive abdominal CT
4.1
9.2
36
99
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
2.4
9.0
107
611
R51.80
ICD-10 Finland
Headache
3.3
8.7
47
165
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
2.3
8.5
110
645
K45.8
ICD-10 Finland
Other specified abdominal hernia without obstruction or gangrene
+∞
8.4
8
*
Z71.3
ICD-10 Finland
Dietary counselling and surveillance
5.4
8.3
24
48
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
2.9
8.3
53
211
Z01.8
ICD-10 Finland
Other specified special examinations
2.8
8.1
58
247
SPAT1262
SPAT
Handing over of treatment supplies
3.1
8.0
46
171
G47.3
ICD-10 Finland
Sleep apnoea
2.7
8.0
60
262
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
2.6
8.0
69
328
J01DB01
ATC
cefalexin; oral
2.6
7.7
199
1588
R10.1
ICD-10 Finland
Pain localized to upper abdomen
3.1
7.7
44
163
M75.1
ICD-10 Finland
Rotator cuff syndrome
3.1
7.7
44
164
N03AX16
ATC
pregabalin; oral
2.8
7.6
53
222
SPAT1249
SPAT
Treatment-related counselling outside office
2.2
7.6
106
637
L03
ICPC
Low back symptom/complaint
2.6
7.5
62
286
A02BC05
ATC
esomeprazole; systemic
2.3
7.4
93
528
J01AA02
ATC
doxycycline; systemic
2.3
7.4
183
1407
QBE20
NOMESCO Finland
Excision and repair of scar or web of skin of trunk
+∞
7.3
7
*
L57.4
ICD-10 Finland
Cutis laxa senilis
+∞
7.3
7
*
M79.1
ICD-10 Finland
Myalgia
3.6
7.3
33
103
M65.3
ICD-10 Finland
Trigger finger
16.4
7.3
11
7
QBB10
NOMESCO Finland
Major dressing of wound of skin of trunk
6.4
7.2
18
30
E66.8
ICD-10 Finland
Other obesity
4.6
7.2
24
57
G56.0
ICD-10 Finland
Carpal tunnel syndrome
3.6
7.2
32
99
R03AC02
ATC
salbutamol; inhalant
2.1
7.0
126
836
MCA10
NOMESCO Finland
Lower uterine segment caesarean section
2.9
7.0
46
184
SPAT1263
SPAT
Sampling
2.1
6.9
109
684
J01FA10
ATC
azithromycin; systemic
2.1
6.9
140
973
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
3.2
6.8
35
121
M79.0
ICD-10 Finland
Rheumatism, unspecified
23.3
6.7
9
*
N02AJ06
ATC
codeine and paracetamol; systemic
2.2
6.7
87
502
SPAT1153
SPAT
Removal of sutures
2.3
6.7
72
382
GD1AA
NOMESCO Finland
Thorax X-ray examination
2.1
6.6
88
513
T90
ICPC
Diabetes non-insulin dependent
2.5
6.5
53
243
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
3.1
6.5
36
129
UJF32
NOMESCO Finland
Coloscopy
2.4
6.5
59
286
SFA10
NOMESCO Finland
Fillning on one surface of tooth
2.0
6.5
132
909
M79.7
ICD-10 Finland
Fibromyalgia
14.8
6.5
10
7
H02AB06
ATC
prednisolone; systemic
2.1
6.4
103
644
A10BA02
ATC
metformin; oral
2.3
6.4
65
333
N06AX21
ATC
duloxetine; oral
3.6
6.3
27
81
K42
ICD-10 Finland
Umbilical hernia
18.6
6.3
9
5
SPAT1310
SPAT
Counselling related to known health issue
2.2
6.3
78
436
4211
FHL
Transeptal septal resection and reconstruction
27.5
6.3
8
*
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
2.7
6.2
43
180
WYA05
NOMESCO Finland
Emergency visit or other similar visit involving procedures
2.0
6.2
123
832
WX408
NOMESCO Finland
General anesthesy, balanced
2.3
6.2
65
337
J01FF01
ATC
clindamycin; systemic
2.3
6.0
64
334
R01AD09
ATC
mometasone; nasal
2.0
6.0
112
740

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
120
591
2.81
15.51
3.0
2.2
56.8
56.0
u/l
0.05
109
552
170
1033
2.66
14.01
4.9
4.0
—
—
—
0
0
21
33
6.80
13.02
3.0
3.0
3.7
2.8
mmol/l
—
10
21
21
33
6.80
13.02
2.5
2.9
—
—
—
0
0
130
734
2.45
11.96
12.9
7.9
1.2
1.2
inr
0.23
53
250
161
1011
2.41
11.53
5.8
6.5
10.4
11.3
umol/l
0.77
150
956
177
1174
2.40
10.98
4.9
4.6
6.6
6.6
mmol/l
0.11
160
1072
100
546
2.30
9.48
5.0
3.6
0.0
0.0
estimate
0.50
39
210
158
1048
2.18
9.14
4.6
3.2
0.0
0.0
estimate
0.00
42
212
158
1058
2.14
8.80
5.7
4.5
0.0
0.0
estimate
0.50
41
216
266
2255
5.16
8.72
17.4
12.3
139.6
139.6
mmol/l
0.07
261
2192
16
29
5.79
8.60
2.2
2.5
16.7
17.3
%
—
8
15
158
1067
2.11
8.50
4.6
3.3
0.0
0.0
estimate
0.00
42
203
266
2263
5.06
8.49
17.6
12.4
3.9
3.9
mmol/l
0.15
261
2194
129
808
2.11
8.47
4.8
4.6
36.1
36.2
g/l
0.03
119
756
212
1612
2.33
8.33
7.3
6.9
72.1
78.2
u/l
1.66
203
1512
223
1740
2.42
8.12
4.6
3.9
14.6
14.4
pmol/l
0.39
200
1599
94
529
2.17
8.07
3.7
3.3
—
—
—
0
0
114
693
2.09
7.99
4.5
3.3
19.8
35.5
ng/l
1.72
72
429
100
585
2.11
7.71
3.2
3.0
8.3
8.0
mmol/l
0.32
86
502
89
498
2.16
7.70
3.0
2.0
3.0
2.8
mg/l
0.40
77
435
46
192
2.67
7.68
5.2
3.1
—
—
—
0
0
12
18
6.92
7.67
1.1
1.9
89.4
89.2
%
0.04
12
18
52
235
2.49
7.37
1.6
1.5
—
—
—
0
0
54
249
2.45
7.33
2.2
2.1
—
—
—
0
0
261
2238
3.72
7.23
15.6
11.4
21.5
21.4
mg/l
0.01
220
1715
75
404
2.17
7.07
2.7
2.5
6.8
7.8
e6/l
0.14
69
353
196
1490
2.07
7.03
4.8
3.7
—
—
—
0
0
94
555
2.05
6.95
4.3
3.9
2.9
9.2
mg/mmol
2.38
57
367
76
415
2.14
6.91
2.0
1.7
437.5
19676964.6
pmol/l
0.50
63
371
62
313
2.26
6.83
2.0
1.7
1479.6
1140.4
nmol/l
1.44
46
240
149
1038
1.94
6.79
4.4
5.5
0.5
0.6
e9/l
0.31
136
904
149
1042
1.93
6.68
4.4
5.5
0.0
0.0
e9/l
0.26
137
905
12
21
5.93
6.64
1.2
2.0
1.9
1.6
mmol/l
0.45
12
21
200
1547
2.04
6.63
3.9
3.5
10.1
10.5
mm/h
0.19
191
1427
88
521
2.01
6.38
3.4
3.2
22.0
302.3
mg/l
0.98
52
354
45
204
2.44
6.31
14.0
18.3
1.2
1.2
inr
—
5
31
151
1074
1.89
6.30
4.4
5.9
0.2
0.2
e9/l
0.06
139
950
153
1108
1.85
5.88
3.2
2.7
100.7
91.6
ug/l
0.32
142
1036
165
1225
1.85
5.84
5.2
9.2
4.2
4.1
e9/l
0.50
153
1070
149
1072
1.84
5.84
4.5
5.5
1.9
2.0
e9/l
0.25
139
952
112
738
1.87
5.81
2.2
1.9
97.3
94.6
pmol/l
0.22
59
419
59
315
2.11
5.59
1.8
1.9
—
—
—
0
0
76
447
1.96
5.52
1.7
1.4
23.6
20.7
nmol/l
0.69
65
385
78
463
1.95
5.52
4.3
4.0
—
—
—
0
0
131
923
1.79
5.35
4.6
7.0
1.2
1.2
mmol/l
0.60
103
785
106
701
1.83
5.35
2.4
2.2
—
—
—
0
0
102
668
1.83
5.30
5.0
5.3
—
—
—
0
0
243
2089
2.30
5.19
5.4
4.5
1.8
1.8
mu/l
0.50
221
1937
83
517
1.86
5.02
1.7
1.9
104.2
217.4
u/l
2.29
75
483
67
389
1.95
5.01
2.7
2.7
572.6
580.8
mosm/kgh2o
0.11
62
330
74
445
1.90
4.99
4.6
3.6
1.0
1.0
kg/l
0.70
11
64
131
939
1.75
4.93
4.7
5.5
0.7
0.7
%
0.06
125
883
88
567
1.81
4.74
3.1
4.0
7.4
7.4
ph
0.96
29
107
49
259
2.08
4.74
2.1
2.3
27.5
24.4
%
0.52
41
229
12
29
4.28
4.67
2.9
2.7
4.7
4.6
e9/l
0.07
12
29
96
638
1.77
4.65
4.0
2.9
—
—
—
0
0
29
124
2.49
4.59
1.3
1.3
—
—
—
0
0
233
2001
2.02
4.52
6.8
4.8
39.5
38.7
mmol/mol
0.76
225
1893
80
508
1.81
4.49
1.3
1.2
6.0
2.2
u/ml
0.47
29
141
12
30
4.14
4.48
2.9
3.0
65.8
58.4
%
1.21
12
30
116
822
1.71
4.43
4.7
6.4
1.2
1.2
mmol/l
0.93
110
760
82
528
1.78
4.38
2.9
2.7
—
—
—
0
0
266
2425
3.25
4.27
18.4
10.8
—
—
—
0
0
244
2147
2.12
4.16
5.3
3.8
5.9
5.8
mmol/l
1.36
226
1984
71
444
1.80
4.16
4.4
3.3
—
—
—
0
0
48
264
1.99
4.16
1.3
1.2
—
—
—
0
0
131
973
1.66
4.10
5.0
5.5
2.7
2.6
%
0.10
125
913
96
658
1.70
4.08
2.1
3.3
2.3
2.3
mmol/l
0.53
87
599
82
538
1.74
4.08
2.9
2.8
0.1
0.4
e6/l
2.88
73
396
18
64
2.94
4.04
2.0
1.4
37.9
39.9
nmol/l
0.14
18
64
131
976
1.65
4.03
9.3
8.5
0.0
0.0
e9/l
0.48
115
808
182
1479
1.67
3.93
4.4
3.2
—
—
—
0
0
59
356
1.83
3.87
1.5
1.2
37.0
26.6
iu/ml
0.25
18
106
80
532
1.71
3.76
4.5
4.6
—
—
—
0
0
88
601
1.68
3.74
2.9
2.9
29.4
159.5
e6/l
0.62
78
453
71
458
1.74
3.71
1.7
1.6
0.9
1.1
mg/l
0.39
54
352
87
595
1.67
3.67
3.0
2.5
—
—
—
0
0
101
721
1.63
3.59
3.1
3.3
81.8
66.1
e6/l
0.12
84
493
52
310
1.83
3.53
2.1
2.2
13.8
14.2
umol/l
0.14
44
289
8
13
6.30
3.52
1.5
1.3
5.2
7.2
mmol/l
—
8
13
131
1007
1.57
3.36
4.6
5.3
58.1
57.0
%
0.55
126
953
28
140
2.11
3.13
3.6
4.4
0.2
0.2
%
—
6
39
262
2421
2.43
3.13
11.7
8.8
25.9
25.5
u/l
0.18
255
2349
28
141
2.10
3.08
3.6
4.4
1.0
0.5
%
—
5
33
98
722
1.55
2.95
1.6
1.6
—
—
—
0
0
38
218
1.86
2.91
1.3
1.3
—
—
—
0
0
13
47
2.85
2.86
1.8
1.3
311.0
312.9
ug/g
—
8
25
21
97
2.26
2.85
4.0
4.3
—
—
—
0
0
14
53
2.73
2.84
1.0
1.1
—
—
—
0
0
71
490
1.60
2.82
2.4
2.6
348.4
8028.9
umol/l
2.69
64
437
8
18
4.54
2.81
2.8
3.6
—
—
—
0
0
11
37
3.05
2.72
2.4
2.1
—
—
—
0
0
23
114
2.11
2.65
2.5
4.8
5.1
5.1
kpa
0.21
23
106
44
273
1.73
2.61
1.4
1.3
306.7
474.7
titre
—
6
53
7
15
4.76
2.61
1.6
1.1
—
—
—
0
0
13
50
2.68
2.57
2.3
2.8
25.2
24.8
mmol/l
0.13
13
39
5
7
7.25
2.56
1.0
1.1
—
—
—
0
0
248
2279
1.82
2.50
5.4
4.2
2.8
2.8
mmol/l
0.11
232
2132
22
111
2.07
2.43
2.5
4.9
7.4
7.4
ph
—
8
13
27
148
1.91
2.38
3.6
4.3
0.0
0.1
%
—
5
45
5
8
6.34
2.38
1.0
1.0
—
—
—
0
0
244
2240
1.73
2.36
5.0
3.8
1.4
1.5
mmol/l
2.00
228
2098
25
136
1.92
2.26
3.5
3.6
—
—
—
0
0
14
61
2.36
2.18
5.0
4.8
—
—
—
0
0
6
14
4.35
2.16
3.3
1.4
—
—
—
0
0
28
161
1.82
2.15
3.6
4.2
0.6
0.9
%
—
5
53
49
330
1.59
2.13
3.1
3.5
156.7
516.8
ng/l
0.78
31
238
238
2185
1.62
2.12
12.8
12.2
39.8
39.9
%
0.04
153
1716
31
185
1.76
2.12
1.1
1.3
129.6
164.3
iu/ml
0.16
11
79
19
96
2.05
2.11
6.4
7.4
24.0
24.2
mmol/l
0.11
19
89
5
10
5.07
2.08
1.0
1.1
—
—
—
0
0
48
324
1.58
2.07
1.4
1.2
1.1
8.0
u/ml
2.12
19
133
34
211
1.70
2.03
3.6
2.6
13.6
7.9
umol/l
0.49
28
181
24
134
1.87
2.03
2.0
2.2
17789.0
2527.3
u/l
—
6
65
243
2249
1.64
2.01
5.1
3.8
4.7
4.7
mmol/l
0.05
228
2116
19
99
1.99
1.95
2.4
3.7
—
—
—
0
0
5
11
4.61
1.95
1.0
1.0
—
—
—
0
0
24
136
1.84
1.94
2.5
2.2
2.1
9.6
ug/l
2.80
24
121
18
93
2.00
1.90
2.9
3.0
1.3
1.3
%
0.02
18
93
9
34
2.70
1.88
4.1
3.1
—
—
—
0
0
27
161
1.75
1.86
3.0
3.7
2.5
1.7
mmol/l
0.55
20
119
6
17
3.58
1.84
5.2
3.5
—
—
—
0
0
24
139
1.80
1.82
1.4
1.2
—
—
—
0
0
8
29
2.81
1.80
1.1
1.3
—
—
—
0
0
8
29
2.81
1.80
1.1
1.0
—
—
—
0
0
8
29
2.81
1.80
1.3
1.1
—
—
—
0
0
49
345
1.51
1.76
2.0
2.6
2.4
2.4
mmol/l
0.04
42
303
12
54
2.28
1.76
3.2
3.0
—
—
—
0
0
13
61
2.19
1.74
2.0
3.7
0.3
0.2
g/l
—
8
27
72
549
1.42
1.73
1.9
1.6
1.5
1.4
mmol/l
0.52
57
465
5
13
3.90
1.72
1.0
1.2
18410.0
655861.0
e6/l
—
5
8
13
62
2.15
1.68
1.2
1.1
—
—
—
0
0
16
83
1.98
1.68
1.8
1.4
—
—
—
0
0
26
160
1.69
1.62
3.0
3.7
5.7
5.6
kpa
0.22
26
155
5
14
3.62
1.62
1.0
1.0
—
—
—
0
0
233
2163
1.48
1.60
4.5
3.5
1.4
1.2
mmol/l
1.44
220
2025
63
478
1.41
1.55
1.2
1.4
2.4
2.3
g/l
0.25
43
310
67
514
1.40
1.55
3.4
6.5
—
—
—
0
0
23
139
1.71
1.54
2.4
2.6
77.6
69.7
e9/l
0.68
18
101
14
73
1.97
1.46
1.3
1.2
—
—
—
0
0
11
52
2.16
1.46
2.4
5.8
8.7
8.6
kpa
0.11
11
47
5
16
3.16
1.44
1.8
1.4
—
—
—
0
0
5
16
3.16
1.44
1.2
1.9
12.5
14.9
ug/l
—
5
16
24
151
1.65
1.40
5.2
8.5
131.5
120.7
g/l
1.47
24
146
20
317
0.60
1.38
1.3
1.3
—
—
—
0
0
5
17
2.97
1.36
2.2
2.6
—
—
—
0
0
115
976
1.30
1.35
3.1
2.5
—
—
—
0
0
107
900
1.31
1.34
2.1
2.0
—
—
—
0
0
22
137
1.66
1.34
2.9
3.2
4.6
4.8
kpa
0.22
22
132
16
91
1.80
1.32
2.6
2.2
—
—
—
0
0
5
18
2.81
1.29
1.2
1.3
—
—
—
0
0
216
2003
1.35
1.28
15.5
14.0
13.6
13.6
%
0.00
209
1961
8
35
2.32
1.28
1.1
1.0
—
—
—
0
0
17
100
1.75
1.26
1.8
1.4
—
—
—
0
0
8
36
2.26
1.25
2.4
2.1
—
—
—
0
0
17
101
1.73
1.23
1.8
1.4
—
—
—
0
0
17
101
1.73
1.23
1.8
1.4
—
—
—
0
0
17
102
1.71
1.19
1.8
1.4
—
—
—
0
0
13
72
1.85
1.17
2.1
1.8
—
—
—
0
0
17
103
1.69
1.15
5.5
11.9
93.4
93.8
%
0.13
17
103
13
73
1.82
1.13
1.3
1.7
—
—
—
0
0
16
96
1.71
1.13
1.8
1.4
—
—
—
0
0
19
120
1.63
1.12
3.1
2.8
—
—
—
0
0
39
289
1.41
1.11
2.0
1.6
—
—
—
0
0
5
21
2.41
1.09
3.8
3.8
2.7
3.3
nmol/l
—
5
21
7
32
2.22
1.09
1.0
1.4
—
—
—
0
0
29
204
1.47
1.08
1.4
1.3
—
—
—
0
0
15
90
1.70
1.06
1.1
1.1
—
—
—
0
0
13
75
1.77
1.04
1.2
1.2
—
—
—
0
0
11
62
1.81
0.95
2.2
4.6
—
—
—
0
0
9
52
1.75
0.93
3.3
3.7
3.7
3.9
mmol/l
—
9
46
6
29
2.09
0.90
1.3
3.0
—
—
—
0
0
6
29
2.09
0.90
1.3
3.0
108.8
105.0
mmol/l
—
6
29
6
29
2.09
0.90
1.3
3.0
3.9
4.0
mmol/l
—
6
29
27
196
1.42
0.88
1.1
1.2
—
—
—
0
0
11
64
1.75
0.87
1.9
2.1
5.4
0.3
ug/l
0.58
11
58
20
137
1.50
0.87
1.7
1.3
—
—
—
0
0
6
31
1.96
0.85
1.0
1.2
—
—
—
0
0
38
299
1.31
0.77
1.3
1.2
—
—
—
0
0
32
247
1.33
0.74
1.6
1.3
—
—
—
0
0
5
25
2.02
0.73
1.0
1.1
—
—
—
0
0
12
76
1.61
0.73
2.8
1.6
—
—
—
0
0
58
487
1.24
0.72
1.8
1.7
—
—
—
0
0
9
59
1.54
0.69
3.4
5.4
1.6
1.6
%
—
9
54
7
44
1.61
0.65
1.0
1.5
—
—
—
0
0
8
49
1.65
0.62
1.3
1.6
—
—
—
0
0
0
20
0.00
0.60
0.0
14.5
—
962.5
—
0
20
0
21
0.00
0.60
0.0
19.7
—
1655.0
—
0
21
8
55
1.47
0.56
2.3
1.2
—
—
—
0
0
10
65
1.56
0.56
2.7
6.5
24.1
25.0
mmol/l
—
10
65
6
38
1.59
0.54
2.0
2.8
—
—
—
0
0
21
162
1.32
0.51
2.9
4.8
—
—
—
0
0
13
93
1.42
0.49
1.5
1.5
132.9
237.3
miu/ml
—
5
46
11
76
1.47
0.49
2.5
5.6
—
—
—
0
0
10
68
1.49
0.47
12.4
6.8
—
—
—
0
0
19
148
1.30
0.45
6.1
10.0
—
—
—
0
0
0
16
0.00
0.41
0.0
3.5
—
12.3
—
0
16
0
17
0.00
0.41
0.0
1.1
—
—
—
0
0
5
34
1.48
0.40
4.8
3.0
—
—
—
0
0
5
35
1.44
0.39
1.4
1.4
—
—
—
0
0
65
586
1.14
0.38
1.8
1.9
—
—
—
0
0
12
89
1.36
0.38
1.2
1.2
—
—
—
0
0
5
36
1.40
0.38
1.2
1.1
—
—
—
0
0
9
70
1.30
0.37
1.3
1.4
1.3
1.2
g/l
—
9
64
11
86
1.29
0.26
7.8
12.7
—
—
—
0
0
13
105
1.25
0.25
1.2
1.1
—
—
—
0
0
0
11
0.00
0.21
0.0
2.5
—
—
—
0
0
0
11
0.00
0.21
0.0
1.3
—
—
—
0
0
0
11
0.00
0.21
0.0
1.6
—
—
—
0
0
0
11
0.00
0.21
0.0
3.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
3.9
—
0
10
0
10
0.00
0.21
0.0
1.7
—
—
—
0
0
0
13
0.00
0.21
0.0
1.8
—
1.0
—
0
13
9
111
0.80
0.20
1.3
1.4
—
—
—
0
0
9
111
0.80
0.20
1.3
1.4
—
—
—
0
0
17
197
0.85
0.20
1.3
1.4
—
—
—
0
0
0
14
0.00
0.20
0.0
2.3
—
—
—
0
0
17
195
0.86
0.18
1.4
1.4
—
—
—
0
0
40
375
1.08
0.13
1.6
1.7
—
—
—
0
0
17
189
0.89
0.12
1.2
1.7
—
—
—
0
0
10
115
0.86
0.11
1.4
1.5
—
—
—
0
0
12
106
1.14
0.10
1.1
3.0
—
—
—
0
0
20
184
1.09
0.09
1.8
1.5
—
—
—
0
0
6
57
1.05
0.08
1.8
1.7
—
—
—
0
0
31
293
1.07
0.08
1.5
1.4
—
—
—
0
0
37
355
1.05
0.06
3.3
2.9
0.6
0.8
ug/l
1.14
27
231
0
5
0.00
0.00
0.0
2.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
8
82
0.97
0.00
4.9
3.8
25.5
23.9
mmol/l
—
8
75
0
8
0.00
0.00
0.0
1.5
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
1.5
—
—
—
0
0
0
6
0.00
0.00
0.0
1.5
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
151.4
—
0
8
0
8
0.00
0.00
0.0
3.4
—
48.6
—
0
8
0
5
0.00
0.00
0.0
3.4
—
—
—
0
0
0
8
0.00
0.00
0.0
1.6
—
—
—
0
0
5
55
0.91
0.00
1.2
1.1
—
—
—
0
0
0
8
0.00
0.00
0.0
1.6
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
0
7
0.00
0.00
0.0
2.4
—
2.2
—
0
7
0
6
0.00
0.00
0.0
3.8
—
6.1
—
0
6
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
2.3
—
1.2
—
0
6
0
7
0.00
0.00
0.0
2.4
—
4.2
—
0
7

Mortality – FinRegistry

Association

Association between endpoint M13_DIASTASIS and mortality.

Females

No data

Males

Parameter HR [95% CI] p-value
M13_DIASTASIS 0.982 [0.75, 1.28] 0.891
Birth year 0.99 [0.98, 1.0] 0.051

During the follow-up period (1.1.1998 — 31.12.2019), 73 out of 493 males with M13_DIASTASIS died.

Mortality risk

Mortality risk for people of age

years, who have M13_DIASTASIS.

N-year risk Females Males
1 No data 0.197%
5 No data 1.252%
10 No data 3.111%
15 No data 5.867%
20 No data 10.226%

Relationships between endpoints

Index endpoint: M13_DIASTASIS – Diastasis of muscle

GWS hits: 2

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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