Unequal limb length (acquired)

M13_LIMBLENGTH

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 M21.7
  • Cause of death: ICD-10 M21.7

2 out of 7 registries used, show all original rules.

357

4. Check minimum number of events

None

357

5. Include endpoints

None

357

6. Filter based on genotype QC (FinnGen only)

357

Control definitions (FinnGen only)

Control exclude
M13_ARTHROPATHIES

Extra metadata

Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
M21
Name in latin
Inaequalitas hongitudinis membrorum (acquisita)

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 5169 2272 2894
Only index persons 4933 2151 2782
Unadjusted period prevalence (%)
Whole population 0.07 0.07 0.08
Only index persons 0.09 0.08 0.11
Median age at first event (years)
Whole population 13.10 12.57 13.51
Only index persons 13.24 12.74 13.63

-FinnGen-

Key figures

All Female Male
Number of individuals 357 218 139
Unadjusted period prevalence (%) 0.07 0.07 0.06
Median age at first event (years) 14.20 14.08 14.38

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
316
Matched controls
3159
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
M21.7
ICD-10 Finland
Unequal limb length (acquired)
+∞
323.0
316
*
NFK20
NOMESCO Finland
Epiphysiodesis of femur
413.4
37.9
37
*
NGK20
NOMESCO Finland
Epiphysiodesis of knee or lower leg
345.2
31.4
31
*
NJ2MA
NOMESCO Finland
Measurement of mechanical axis of lower leg with X-ray
141.1
25.0
26
*
M16.1
ICD-10 Finland
Other primary coxarthrosis
82.5
21.0
23
*
NA7EA
NOMESCO Finland
Scoliosis X-ray examination
24.5
19.4
27
12
M17.1
ICD-10 Finland
Other primary gonarthrosis
24.5
18.0
25
11
M41.1
ICD-10 Finland
Juvenile idiopathic scoliosis
15.8
18.0
29
20
NFU20
NOMESCO Finland
Removal of internal fixation device from femur
39.2
17.8
22
6
M25.5
ICD-10 Finland
Pain in joint
3.8
16.2
76
243
TNX10
NOMESCO Finland
Arthrocentesis, unspecified region, unspecified region
28.0
15.8
21
8
NG1AA
NOMESCO Finland
Knee X-ray examination without contrast
7.5
15.2
36
53
NF1AA
NOMESCO Finland
Hip X-ray examination
15.2
14.8
24
17
NFB30
NOMESCO Finland
Primary total prosthetic replacement of hip joint not using cement
78.6
13.7
15
*
T84.0
ICD-10 Finland
Mechanical complication of internal joint prosthesis
146.0
13.6
14
*
NK6JD
NOMESCO Finland
Ortopaedic measurement of extemities with CT
+∞
12.6
12
*
NGB20
NOMESCO Finland
Primary total prosthetic replacement of knee joint without patellar part
135.1
12.5
13
*
M23.2
ICD-10 Finland
Derangement of meniscus due to old tear or injury
135.1
12.5
13
*
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
7.6
12.1
28
40
M51.3
ICD-10 Finland
Other specified intervertebral disc degeneration
7.1
12.1
29
44
N03AX12
ATC
gabapentin; oral
4.2
10.5
40
105
M70.6
ICD-10 Finland
Trochanteric bursitis
5.7
10.3
29
55
N02AX02
ATC
tramadol; systemic, rectal
2.6
10.2
86
397
Y83
ICD-10 Finland
Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
8.0
9.6
21
28
M19.0
ICD-10 Finland
Primary arthrosis of other joints
31.1
9.5
12
*
NE1CG
NOMESCO Finland
Pelvic, hip and femur extensive MRI examination with high intensity magnet
31.1
9.5
12
*
M16.0
ICD-10 Finland
Primary coxarthrosis, bilateral
103.0
9.5
10
*
M08.4
ICD-10 Finland
Pauciarticular juvenile arthritis
+∞
9.4
9
*
ZXA00
NOMESCO Finland
Right side
2.8
9.4
63
254
NK6MA
NOMESCO Finland
Measurement of bone age from hand and elbow using X-ray
7.1
9.3
22
33
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
2.3
9.0
105
570
M21.4
ICD-10 Finland
Flat foot [pes planus] (acquired)
19.3
9.0
13
7
L13
ICPC
Hip symptom/complaint
4.2
9.0
34
89
WX320
NOMESCO Finland
Spinalanesthesy
3.1
8.6
49
178
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
3.7
8.5
37
110
NJ3NA
NOMESCO Finland
Measurement of difference in extremity lengty with X-ray
92.4
8.5
9
*
Q72.88
ICD-10 Finland
Other reduction defects of lower himb(s)
92.4
8.5
9
*
NK4XE
NOMESCO Finland
Joint ultrasound examination not elsewhere classified
10.4
8.1
15
15
N03AX16
ATC
pregabalin; oral
3.0
8.1
49
184
M75.1
ICD-10 Finland
Rotator cuff syndrome
3.2
8.0
44
153
S82.2
ICD-10 Finland
Fracture of shaft of tibia
8.1
8.0
17
22
M13.9
ICD-10 Finland
Arthritis, unspecified
9.8
7.9
15
16
NH3AA
NOMESCO Finland
Foot and toes X-ray examination
5.0
7.8
24
51
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
4.8
7.8
25
56
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
2.3
7.7
76
379
M15.9
ICD-10 Finland
Polyarthrosis, unspecified
18.9
7.7
11
6
B01AB05
ATC
enoxaparin; parenteral
2.6
7.6
59
259
NFK50
NOMESCO Finland
Shortening osteotomy of femur
+∞
7.3
7
*
M21.0
ICD-10 Finland
Valgus deformity, not elsewhere classified
+∞
7.3
7
*
NJ3MA
NOMESCO Finland
Measurement of extremity length with X-ray
+∞
7.3
7
*
NFC20
NOMESCO Finland
Secondary implantation of hip prosthesis
+∞
7.3
7
*
NGU20
NOMESCO Finland
Removal of internal fixation device from knee or lower leg
12.4
7.1
12
10
L04AX03
ATC
methotrexate; systemic (immunosuppressants)
6.6
7.0
17
27
NG1BG
NOMESCO Finland
Knee and lower leg MRI examination with high intensity magnet
9.6
6.8
13
14
M41.9
ICD-10 Finland
Scoliosis, unspecified
9.6
6.8
13
14
S72.3
ICD-10 Finland
Fracture of shaft of femur
17.1
6.8
10
6
NFK30
NOMESCO Finland
Angulation, rotation or displacement osteotomy of femur
40.9
6.8
8
*
NA3BG
NOMESCO Finland
Lumbar spine MRI examination with high intensity magnet
4.1
6.8
25
65
M54.4
ICD-10 Finland
Lumbago with sciatica
2.9
6.7
40
151
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
3.7
6.5
27
78
M79.6
ICD-10 Finland
Pain in limb
2.1
6.5
88
499
M20.4
ICD-10 Finland
Other hammer toe(s) (acquired)
71.2
6.4
7
*
9165
FHL
Removal of osteosynthesis material
14.7
6.4
10
7
NE1AA
NOMESCO Finland
Pelvis X-ray examination
6.8
6.4
15
23
L04AA13
ATC
leflunomide; oral
+∞
6.3
6
*
M22.0
ICD-10 Finland
Recurrent dislocation of patella
+∞
6.3
6
*
NF1DA
NOMESCO Finland
X-ray of hips
27.3
6.3
8
*
ZXA05
NOMESCO Finland
Left side
2.5
6.2
49
216
202
Kela drug reimbursment
Connective tissue diseases, rheumatoid arthritis and comparable disease
4.9
6.2
19
41
N02BE01
ATC
paracetamol; systemic, rectal
1.9
6.2
224
1787
P01BA02
ATC
hydroxychloroquine; oral
7.9
6.2
13
17
ZXM10
NOMESCO Finland
Intraoperative use of conventional X-ray imaging
5.1
6.1
18
37
M43.1
ICD-10 Finland
Spondylolisthesis
8.9
6.1
12
14
GD1AA
NOMESCO Finland
Thorax X-ray examination
2.0
6.1
86
496
M01AH05
ATC
etoricoxib; oral
1.9
6.1
117
754
M75.4
ICD-10 Finland
Impingement syndrome of shoulder
6.2
6.1
15
25

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
126
771
1.98
8.21
6.2
5.5
—
—
—
0
0
116
720
1.91
7.07
2.2
2.0
—
—
—
0
0
162
1142
1.77
6.38
6.7
5.4
0.6
0.6
%
0.17
152
1065
166
1184
1.75
6.24
6.6
5.2
2.9
2.7
%
0.43
156
1104
177
1294
1.73
6.03
6.4
5.5
0.2
0.2
e9/l
0.26
161
1133
166
1193
1.73
6.01
6.7
5.5
8.5
8.2
%
0.69
157
1121
52
262
2.15
5.58
1.2
1.4
708.6
477.1
titre
—
7
42
178
1323
1.69
5.56
6.3
5.1
1.9
2.1
e9/l
1.21
165
1170
170
1252
1.68
5.47
6.4
5.0
55.6
55.4
%
0.09
160
1179
169
1243
1.68
5.46
6.5
5.2
0.6
0.5
e9/l
0.78
152
1066
8
5
16.31
5.43
2.1
1.0
—
—
—
0
0
172
1274
1.68
5.39
6.6
5.1
30.4
30.8
%
0.21
163
1194
169
1248
1.67
5.35
6.5
5.2
0.0
0.0
e9/l
0.19
152
1069
215
1694
1.68
5.27
7.6
5.6
77.3
77.4
u/l
0.01
198
1574
104
697
1.69
4.62
2.6
2.4
—
—
—
0
0
155
1163
1.59
4.34
4.5
3.9
—
—
—
0
0
123
874
1.62
4.32
1.7
1.8
—
—
—
0
0
144
1066
1.59
4.25
5.0
5.3
10.0
10.8
umol/l
0.62
129
996
185
1461
1.55
4.06
8.0
7.8
3.8
4.0
e9/l
0.55
164
1257
112
788
1.61
4.05
4.6
4.5
37.9
37.6
g/l
0.26
106
738
74
467
1.74
4.05
2.6
2.5
—
—
—
0
0
76
484
1.72
4.02
2.2
2.0
0.6
0.9
mg/l
1.86
59
319
43
231
1.98
3.90
1.1
1.1
—
—
—
0
0
32
154
2.18
3.86
4.0
4.7
0.4
0.5
%
—
5
37
92
624
1.64
3.83
2.7
2.5
17.3
41.0
ng/l
1.13
49
294
11
29
3.88
3.83
2.8
2.0
18.1
17.5
%
—
6
10
50
287
1.86
3.73
1.3
1.1
12.7
1.4
u/ml
0.54
22
112
119
867
1.56
3.66
6.4
5.6
1.2
1.2
mmol/l
0.14
112
788
52
306
1.82
3.59
1.4
1.1
19.1
12.8
iu/ml
0.47
11
78
17
64
2.74
3.44
1.3
3.5
—
—
—
0
0
170
1352
1.49
3.41
4.5
4.2
6.1
6.2
mmol/l
0.40
156
1188
205
1702
1.48
3.26
4.6
2.8
8.7
8.2
mm/h
0.25
189
1558
87
607
1.57
3.18
4.5
3.7
—
—
—
0
0
126
956
1.49
3.13
7.3
6.0
1.2
1.2
mmol/l
0.40
108
821
31
163
1.99
3.01
4.8
5.1
0.0
0.2
%
—
8
46
30
156
2.01
3.00
4.6
6.7
—
—
—
0
0
5
5
10.12
2.98
2.8
1.8
—
—
—
0
0
5
5
10.12
2.98
2.8
1.8
9.0
4.8
%
—
5
5
40
230
1.83
2.98
1.2
1.6
—
—
—
0
0
30
158
1.98
2.90
4.7
5.1
0.0
0.1
%
—
7
42
209
1767
1.44
2.87
4.4
3.5
—
—
—
0
0
62
411
1.62
2.79
2.9
3.4
28.7
97.0
mg/l
2.34
39
283
11
37
3.04
2.71
3.9
3.0
3.0
3.5
e9/l
0.39
11
37
31
170
1.90
2.68
4.8
5.0
0.6
1.1
%
—
8
49
93
682
1.49
2.68
5.1
5.4
1.0
1.1
inr
2.52
31
243
29
156
1.93
2.66
1.4
1.2
—
—
—
0
0
21
100
2.17
2.64
4.9
3.8
—
—
—
0
0
11
38
2.95
2.60
5.2
2.2
1.5
2.7
mmol/l
—
6
23
11
38
2.95
2.60
4.2
3.6
49.0
51.9
%
0.25
11
38
5
7
7.22
2.55
2.8
2.6
—
—
—
0
0
5
7
7.22
2.55
2.8
2.6
—
—
—
0
0
6
11
5.53
2.55
2.7
2.0
0.1
0.2
e9/l
—
6
11
64
437
1.57
2.55
4.1
3.5
—
—
—
0
0
87
636
1.49
2.53
3.3
3.0
7.9
8.8
mmol/l
0.84
73
558
91
675
1.47
2.46
3.0
2.7
12.2
66.8
e6/l
3.08
68
502
10
34
3.00
2.43
6.0
2.4
—
—
—
0
0
83
607
1.48
2.41
3.0
2.6
—
—
—
0
0
9
27
3.39
2.41
2.3
1.9
—
—
—
0
0
109
841
1.43
2.39
3.3
3.1
10.9
78.7
e6/l
4.46
73
535
82
602
1.47
2.33
3.1
2.6
0.1
0.3
e6/l
1.96
60
432
64
447
1.53
2.31
2.6
2.3
564.1
561.8
mosm/kgh2o
0.02
56
379
87
649
1.45
2.27
2.4
3.0
2.4
2.4
mmol/l
0.51
81
585
229
2019
1.37
2.17
4.3
3.9
37.1
37.4
mmol/mol
0.19
215
1887
31
184
1.75
2.12
2.1
5.3
1.4
1.9
mmol/l
0.57
24
140
8
25
3.25
2.10
1.8
1.6
1.5
1.8
mmol/l
—
8
25
18
89
2.08
2.09
5.4
4.1
24.5
24.5
mmol/l
0.04
18
89
38
240
1.65
2.09
2.4
2.0
—
—
—
0
0
76
562
1.45
2.07
5.3
3.2
7.4
7.4
ph
0.16
21
105
78
580
1.44
2.07
2.2
1.9
2.5
2.6
mg/l
0.10
67
483
86
652
1.42
2.05
3.0
2.2
50.2
58.0
u/l
1.55
79
594
12
50
2.45
2.04
3.6
2.0
—
—
—
0
0
6
15
4.05
2.04
1.3
1.9
12.2
10.7
umol/l
—
6
15
17
84
2.08
1.99
1.1
1.0
—
—
—
0
0
31
189
1.70
1.95
2.1
5.5
—
—
—
0
0
11
45
2.49
1.95
5.8
2.1
7.4
7.4
ph
0.05
11
37
8
27
3.01
1.94
2.9
3.1
—
—
—
0
0
60
430
1.48
1.92
3.9
4.1
3.6
13.5
mg/mmol
2.68
36
301
238
2131
1.35
1.92
4.5
3.6
14.6
14.5
pmol/l
0.14
219
1930
38
246
1.61
1.91
8.2
6.0
1.1
1.1
mmol/l
0.07
38
232
272
2488
1.39
1.91
5.2
4.2
1.8
1.8
mu/l
0.06
260
2307
7
22
3.22
1.89
1.9
1.6
93.0
92.0
%
—
7
22
160
1356
1.33
1.87
2.9
2.5
98.5
74.6
ug/l
0.79
144
1255
28
168
1.72
1.87
4.6
3.7
—
—
—
0
0
34
216
1.63
1.84
1.7
1.4
—
—
—
0
0
70
521
1.43
1.84
4.2
3.0
—
—
—
0
0
62
451
1.45
1.84
2.8
2.2
6.0
8.2
e6/l
0.69
53
386
16
80
2.05
1.83
1.3
1.6
0.3
0.4
nmol/l
—
9
72
26
154
1.74
1.82
4.5
5.9
1.0
1.3
mmol/l
1.92
26
142
295
2745
1.43
1.79
12.8
8.7
21.2
21.6
mg/l
0.06
234
1968
37
242
1.59
1.79
4.3
3.0
—
—
—
0
0
25
147
1.75
1.79
10.7
7.6
5.7
6.6
mmol/l
0.78
25
142
18
95
1.94
1.79
2.9
1.7
—
—
—
0
0
14
67
2.13
1.78
1.1
1.5
—
—
—
0
0
147
1242
1.31
1.72
3.9
2.9
0.0
0.0
estimate
0.00
38
253
148
1258
1.30
1.64
4.0
2.9
0.0
0.0
estimate
0.50
38
253
12
56
2.18
1.63
1.8
2.7
—
—
—
0
0
276
2554
1.36
1.62
13.0
9.2
3.9
3.9
mmol/l
0.02
269
2451
146
1244
1.29
1.58
5.1
4.0
0.0
0.0
estimate
0.00
37
259
275
2547
1.35
1.57
13.1
9.2
139.3
139.6
mmol/l
1.08
269
2453
55
405
1.42
1.54
3.5
2.5
333.2
6099.3
umol/l
1.77
48
367
10
44
2.31
1.54
2.0
2.7
—
—
—
0
0
311
2941
1.45
1.54
11.5
8.0
—
—
—
0
0
165
1435
1.28
1.50
3.0
2.7
—
—
—
0
0
49
356
1.44
1.48
1.6
1.5
452.3
22112642.0
pmol/l
0.50
35
303
21
125
1.72
1.47
6.2
10.5
96.7
96.4
%
0.17
21
119
39
272
1.49
1.45
1.7
1.6
1064.4
1190.4
nmol/l
0.36
30
205
337
3250
1.66
1.40
18.0
12.7
262.6
257.8
e9/l
0.73
332
3151
82
661
1.31
1.32
4.2
3.0
0.0
0.0
estimate
0.80
38
255
36
253
1.47
1.30
1.8
1.4
—
—
—
0
0
138
1191
1.26
1.30
10.2
7.2
0.0
0.0
e9/l
0.29
121
941
57
437
1.36
1.28
3.7
2.6
122.4
112.0
ug/g
0.11
43
334
337
3258
1.61
1.27
17.9
12.7
4.6
4.6
e12/l
0.94
332
3158
24
155
1.59
1.26
13.1
12.5
1.0
1.1
inr
—
8
34
12
64
1.91
1.19
1.2
1.1
—
—
—
0
0
12
64
1.91
1.19
1.2
1.1
—
—
—
0
0
8
39
2.07
1.16
1.4
1.7
—
—
—
0
0
47
606
0.74
1.11
1.4
1.5
—
—
—
0
0
5
21
2.40
1.09
1.4
3.0
—
—
—
0
0
5
21
2.40
1.09
2.4
2.1
34.0
31.2
pg
—
5
21
34
247
1.42
1.06
1.3
1.2
—
—
—
0
0
12
68
1.79
1.01
10.0
8.0
—
—
—
0
0
248
2318
1.23
1.01
3.6
3.0
5.6
5.6
mmol/l
0.14
231
2138
23
158
1.49
0.96
6.2
8.7
14.2
14.0
kpa
0.05
23
149
23
158
1.49
0.96
6.2
8.7
4.8
5.1
kpa
0.83
23
148
12
70
1.74
0.93
6.5
15.3
—
—
—
0
0
45
351
1.32
0.93
3.2
3.0
47.2
597.8
ng/l
1.30
33
200
14
86
1.65
0.92
4.1
2.7
—
—
—
0
0
6
28
2.16
0.92
1.0
1.5
—
—
—
0
0
53
425
1.29
0.90
1.6
1.3
21.6
20.0
nmol/l
0.40
46
365
13
80
1.65
0.85
3.4
3.9
0.1
0.3
g/l
—
7
41
31
407
0.74
0.85
1.2
1.3
—
—
—
0
0
18
121
1.51
0.84
2.2
6.2
24.2
24.3
mmol/l
0.07
18
114
19
130
1.49
0.82
3.6
2.1
—
—
—
0
0
11
66
1.69
0.79
4.3
3.9
—
—
—
0
0
0
24
0.00
0.79
0.0
1.4
—
—
—
0
0
22
157
1.43
0.78
6.5
8.8
0.4
1.1
mmol/l
0.78
17
120
23
166
1.41
0.78
2.7
2.8
0.2
0.2
g/l
0.10
23
153
71
602
1.22
0.77
7.5
5.9
—
—
—
0
0
0
28
0.00
0.76
0.0
1.3
—
44.5
—
0
19
12
75
1.62
0.76
1.2
1.1
—
—
—
0
0
255
2423
1.18
0.73
3.6
3.1
4.6
4.6
mmol/l
0.15
244
2286
114
1021
1.17
0.69
1.7
1.7
—
—
—
0
0
13
87
1.51
0.64
1.7
1.3
240.0
201.0
u/ml
—
5
51
5
29
1.73
0.64
1.2
1.4
—
—
—
0
0
42
344
1.25
0.63
2.3
2.0
—
—
—
0
0
252
2404
1.16
0.63
3.5
3.0
1.4
1.5
mmol/l
1.83
242
2262
12
79
1.54
0.63
1.8
1.8
2.3
6.5
iu/l
—
5
25
38
308
1.26
0.63
1.8
2.7
2.4
2.4
mmol/l
0.21
33
277
30
377
0.78
0.63
3.1
1.9
—
—
—
0
0
8
52
1.55
0.60
1.0
1.0
—
—
—
0
0
31
384
0.79
0.58
3.1
2.0
—
—
—
0
0
0
23
0.00
0.58
0.0
1.4
—
—
—
0
0
255
2443
1.15
0.57
3.9
3.3
2.8
2.8
mmol/l
0.33
242
2281
31
382
0.79
0.56
3.0
1.9
—
—
—
0
0
12
82
1.48
0.55
11.0
7.3
1.1
1.1
mg/l
0.12
12
76
81
721
1.16
0.53
1.5
1.4
2.3
2.0
g/l
0.75
52
431
12
83
1.46
0.52
1.3
1.1
—
—
—
0
0
63
551
1.17
0.51
1.9
1.6
1.4
1.3
mmol/l
0.35
53
473
31
377
0.81
0.51
3.0
2.0
—
—
—
0
0
288
2793
1.16
0.50
11.1
9.6
40.1
40.8
%
0.82
228
2307
239
2290
1.13
0.50
3.2
2.8
1.3
1.2
mmol/l
1.39
231
2157
11
77
1.44
0.46
1.9
1.8
—
—
—
0
0
15
112
1.35
0.45
1.5
1.8
—
—
—
0
0
25
202
1.26
0.45
1.5
1.3
—
—
—
0
0
5
32
1.57
0.42
1.8
1.2
—
—
—
0
0
0
16
0.00
0.41
0.0
1.2
—
—
—
0
0
0
16
0.00
0.41
0.0
1.0
—
—
—
0
0
0
17
0.00
0.40
0.0
1.3
—
—
—
0
0
28
233
1.22
0.40
1.1
1.3
—
—
—
0
0
10
137
0.72
0.40
1.1
1.2
—
15.9
—
0
7
18
142
1.28
0.39
5.9
2.9
—
—
—
0
0
30
351
0.84
0.36
3.0
2.0
—
—
—
0
0
90
830
1.11
0.35
1.4
1.4
2.1
1.2
u/ml
0.29
31
201
6
45
1.34
0.34
3.0
5.4
368.0
411.9
umol/l
—
6
40
12
92
1.31
0.32
3.9
9.5
—
—
—
0
0
7
54
1.30
0.30
1.7
15.0
1.1
1.1
mmol/l
—
7
47
13
102
1.28
0.30
1.2
1.1
—
—
—
0
0
81
751
1.10
0.29
3.3
2.5
—
—
—
0
0
8
107
0.74
0.29
1.4
1.3
—
—
—
0
0
63
577
1.11
0.29
4.0
2.9
1.0
1.0
kg/l
—
10
77
13
103
1.27
0.28
2.3
2.3
5.0
7.1
ug/l
0.30
13
88
30
262
1.16
0.27
2.4
2.6
—
—
—
0
0
25
286
0.86
0.25
3.4
2.1
—
—
—
0
0
17
201
0.84
0.24
1.5
1.4
—
—
—
0
0
17
201
0.84
0.24
1.5
1.5
—
—
—
0
0
5
38
1.32
0.23
1.6
1.3
—
—
—
0
0
29
258
1.13
0.22
5.2
3.0
5.1
8.2
umol/l
1.03
23
214
0
11
0.00
0.21
0.0
1.4
—
—
—
0
0
0
10
0.00
0.21
0.0
1.2
—
—
—
0
0
0
10
0.00
0.21
0.0
1.3
—
—
—
0
0
0
12
0.00
0.21
0.0
1.1
—
—
—
0
0
17
198
0.85
0.21
1.5
1.4
—
—
—
0
0
0
14
0.00
0.20
0.0
2.6
—
104.9
—
0
14
0
14
0.00
0.20
0.0
2.6
—
4.0
—
0
14
0
14
0.00
0.20
0.0
2.6
—
—
—
0
0
9
113
0.79
0.20
1.9
2.5
28.9
44.1
u/ml
—
9
106
52
559
0.92
0.19
1.4
1.6
—
—
—
0
0
6
53
1.13
0.19
1.2
1.4
—
—
—
0
0
77
730
1.07
0.18
2.1
1.5
99.8
96.1
pmol/l
0.35
37
362
6
80
0.75
0.15
1.0
1.2
—
—
—
0
0
6
80
0.75
0.15
1.2
1.1
—
—
—
0
0
27
295
0.91
0.14
1.4
1.2
—
—
—
0
0
117
1209
0.95
0.14
1.9
2.2
—
—
—
0
0
14
160
0.87
0.14
3.0
2.4
0.8
0.7
ug/l
—
8
86
15
168
0.89
0.12
1.3
1.3
—
—
—
0
0
16
143
1.12
0.11
1.4
1.4
—
—
—
0
0
5
45
1.11
0.10
1.2
1.1
—
—
—
0
0
5
48
1.04
0.09
1.4
1.3
—
—
—
0
0
6
54
1.11
0.09
1.2
1.0
—
—
—
0
0
6
55
1.09
0.09
2.0
13.9
0.7
1.0
%
—
6
49
6
56
1.07
0.08
2.0
13.6
1.4
1.7
%
—
6
48
6
56
1.07
0.08
1.3
1.5
—
—
—
0
0
6
58
1.04
0.08
1.2
1.1
—
—
—
0
0
5
61
0.82
0.08
3.0
1.7
—
—
—
0
0
92
943
0.97
0.08
1.6
1.8
—
—
—
0
0
8
74
1.08
0.07
1.1
1.1
—
—
—
0
0
8
77
1.04
0.07
1.3
1.4
—
—
—
0
0
96
938
1.03
0.07
2.2
2.0
—
—
—
0
0
8
91
0.88
0.07
2.0
1.3
—
—
—
0
0
17
158
1.08
0.06
4.4
2.6
—
—
—
0
0
11
100
1.10
0.05
2.2
2.2
0.0
0.1
e6/l
1.86
11
95
16
150
1.07
0.04
1.3
1.2
—
—
—
0
0
26
249
1.05
0.04
1.2
1.3
—
—
—
0
0
35
361
0.97
0.03
1.2
1.6
—
—
—
0
0
30
307
0.98
0.01
2.9
2.5
9408.4
3501.8
u/l
0.31
11
140
17
164
1.04
0.00
1.3
1.5
—
—
—
0
0
26
254
1.03
0.00
1.3
1.2
84.1
139.7
iu/ml
0.91
13
95
14
139
1.01
0.00
1.4
1.3
—
—
—
0
0
0
6
0.00
0.00
0.0
2.2
—
—
—
0
0
0
6
0.00
0.00
0.0
1.8
—
109.9
—
0
6
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.8
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
1.1
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
113.2
—
0
5
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
0.00
0.0
13.2
—
0.5
—
0
6
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
84
840
1.00
0.00
1.5
1.9
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
2.2
—
—
—
0
0
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
6
59
1.02
0.00
2.5
2.7
—
—
—
0
0
0
6
0.00
0.00
0.0
3.3
—
148.2
—
0
6
0
8
0.00
0.00
0.0
1.3
—
—
—
0
0
0
7
0.00
0.00
0.0
2.0
—
106.5
—
0
7
5
53
0.94
0.00
1.4
2.2
—
—
—
0
0
0
5
0.00
0.00
0.0
6.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.7
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
7.0
—
0
7
0
9
0.00
-0.00
0.0
5.1
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.1
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint M13_LIMBLENGTH and mortality.

Females

No data

Males

No data

Mortality risk

Mortality risk for people of age

years, who have M13_LIMBLENGTH.

N-year risk Females Males
1 No data No data
5 No data No data
10 No data No data
15 No data No data
20 No data No data

Relationships between endpoints

Index endpoint: M13_LIMBLENGTH – Unequal limb length (acquired)

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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