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Multiple myeloma, Monoclonal gammopathy of undetermined significance (MGUS)

Endpoint Browser PheWeb

C3_MYELOMA_MONOCLONAL

Endpoint definition

↥

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

None

0 out of 7 registries used, show all original rules.

0

4. Check minimum number of events

None

0

5. Include endpoints

856

6. Filter based on genotype QC (FinnGen only)

856

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

First used in FinnGen datafreeze
DF12

Case counts by codes

↥

FinnGen case counts by registry codes:

No data for upset plot.

No data for upset table.

Summary Statistics

↥

-FinRegistry-

This endpoint is excluded (different definition than used in FinnGen).

-FinnGen-

Key figures

All Female Male
Number of individuals 856 375 481
Unadjusted period prevalence (%) 0.18 0.13 0.21
Median age at first event (years) 70.29 69.23 71.12

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

CodeWAS (R11)

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

No data available

LabWAS

↥
OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
355
307
19.05
307.65
21.8
1.6
10.7
10.3
g/l
0.35
290
257
288
28
154.50
307.65
3.6
1.1
—
—
—
0
0
516
190
66.86
307.65
18.1
2.4
—
—
—
0
0
321
125
40.49
307.65
1.8
1.6
—
—
—
0
0
369
303
20.65
307.65
21.4
1.6
2.9
3.2
g/l
4.15
261
234
421
72
114.09
307.65
5.7
1.6
—
—
—
0
0
549
269
55.12
307.65
22.6
2.2
143.8
38.3
mg/l
3.61
504
220
563
687
22.02
307.65
23.3
2.1
67.4
66.0
g/l
2.14
549
609
483
453
23.17
307.65
10.6
2.3
13.2
10.7
g/l
3.41
451
411
398
328
21.81
307.65
20.5
1.6
7.0
7.6
g/l
3.77
292
236
398
327
21.88
307.65
20.5
1.6
4.1
3.8
g/l
0.37
260
230
402
361
20.11
307.65
4.9
1.8
0.5
1.7
g/l
4.64
319
328
477
177
59.61
307.65
5.7
1.4
—
—
—
0
0
547
263
55.85
307.65
21.8
2.1
41.3
1.4
ratio
1.60
42
27
548
269
54.84
307.65
22.6
2.2
197.2
50.0
mg/l
2.21
504
217
568
568
27.75
307.65
21.7
1.8
—
—
—
0
0
167
51
40.44
267.11
4.5
1.5
—
—
—
0
0
172
77
27.70
241.81
1.2
1.2
—
—
—
0
0
169
80
26.08
232.22
1.2
1.3
—
—
—
0
0
254
262
13.36
231.54
23.8
1.4
37.2
37.0
g/l
0.20
237
219
255
294
11.93
214.32
1.7
1.3
—
—
—
0
0
102
10
115.66
199.56
4.5
1.8
—
—
—
0
0
419
961
7.58
193.15
4.9
2.2
1.7
1.8
%
1.21
392
848
434
1032
7.50
192.91
6.8
1.4
3.5
2.7
g/l
1.39
368
586
118
33
41.32
192.01
3.3
1.5
2041.2
1749.8
ml
—
14
8
351
713
7.65
180.85
3.8
2.5
61.9
68.1
e9/l
2.15
269
560
281
484
8.15
167.90
1.9
1.4
—
—
—
0
0
276
470
8.19
166.52
1.8
1.4
—
—
—
0
0
130
81
18.74
156.55
1.6
1.3
—
—
—
0
0
389
996
6.33
154.90
11.9
4.8
1.1
1.0
mmol/l
3.22
371
902
90
25
40.11
146.03
2.3
2.0
—
—
—
0
0
268
566
6.44
128.49
1.8
1.4
—
—
—
0
0
492
1814
5.03
121.35
11.7
2.7
1902.7
9082.8
umol/l
4.01
477
1519
127
118
12.46
121.08
1.4
1.1
79.0
35.6
u/l
2.47
119
99
128
150
9.86
103.21
1.5
1.2
—
—
—
0
0
95
72
14.72
102.20
1.5
1.3
166.1
118.3
u/ml
—
15
8
74
34
23.73
101.24
1.7
3.0
27.5
39.9
%
1.42
19
13
349
1141
4.48
96.50
7.5
3.1
0.8
0.8
mmol/l
0.81
342
1050
115
129
10.14
95.63
3.7
3.9
2.0
1.1
%
0.80
92
104
503
2232
4.04
88.66
15.0
5.2
—
—
—
0
0
65
31
22.61
87.41
1.8
2.3
290.7
665.5
e6/l
1.25
18
15
65
31
22.61
87.41
1.7
1.7
29.8
31.2
%
—
5
6
223
566
4.98
84.02
7.0
3.9
1.0
0.9
%
0.25
157
178
67
38
19.04
83.48
3.5
2.2
—
—
—
0
0
96
104
10.27
81.62
1.6
1.2
—
—
—
0
0
181
395
5.54
81.16
2.5
1.7
1.4
1.6
g/l
0.83
165
347
60
30
21.43
79.00
1.3
1.1
—
—
—
0
0
83
9
102.02
76.46
1.6
1.4
—
—
—
0
0
62
36
18.49
76.30
1.7
1.1
—
—
—
0
0
78
5
171.36
75.39
5.2
1.4
—
—
—
0
0
574
2995
3.78
74.90
18.5
5.4
2.7
2.9
%
0.86
554
2753
575
3008
3.78
74.62
19.4
5.6
10.0
8.9
%
10.18
556
2775
562
2920
3.69
73.20
18.0
5.3
0.6
0.6
%
0.82
542
2689
576
3056
3.71
72.23
18.7
5.6
28.2
25.9
%
4.42
556
2795
566
3003
3.61
70.24
17.8
5.3
54.7
58.7
%
10.74
544
2769
77
76
11.03
69.74
1.9
1.3
—
—
—
0
0
77
76
11.03
69.74
1.9
1.3
—
—
—
0
0
77
76
11.03
69.74
1.9
1.3
—
—
—
0
0
77
76
11.03
69.74
1.9
1.3
—
—
—
0
0
80
85
10.28
68.78
3.7
3.8
60.1
54.2
%
0.93
56
61
80
87
10.04
67.60
4.2
4.7
—
—
—
0
0
226
693
4.07
65.18
10.1
6.2
13.2
11.3
mmol/l
2.30
214
654
76
83
9.95
63.97
1.1
1.0
—
—
—
0
0
571
3164
3.42
63.52
19.2
5.1
0.5
0.6
e9/l
17.91
531
2670
572
3179
3.41
63.19
19.3
5.1
0.0
0.0
e9/l
32.85
531
2694
71
73
10.52
62.39
1.5
1.1
210.4
328.6
u/ml
1.25
39
39
580
3285
3.37
61.34
20.0
5.2
0.1
0.2
e9/l
16.12
539
2828
71
75
10.23
61.19
1.1
1.1
—
—
—
0
0
573
3227
3.35
61.08
19.3
5.2
1.5
1.9
e9/l
8.63
536
2783
181
507
4.26
58.63
7.6
3.9
0.8
0.5
%
1.43
100
132
451
2255
3.11
58.29
8.7
4.4
—
—
—
0
0
36
10
37.54
57.61
1.7
1.0
—
—
—
0
0
295
1172
3.31
56.39
3.7
1.8
28.8
29.9
s
2.60
283
1125
78
104
8.15
56.00
1.9
1.2
—
—
—
0
0
182
534
4.06
55.12
7.6
4.0
0.1
0.1
%
0.20
142
164
600
3697
3.08
50.34
43.0
6.4
1.2
1.2
mmol/l
0.65
538
3108
257
1044
3.09
46.03
3.5
2.4
24.1
21.9
%
1.78
221
879
593
3732
2.92
45.90
50.3
8.3
3.0
4.3
e9/l
52.30
552
3237
539
3232
2.80
45.76
17.2
4.5
32.9
34.4
g/l
7.56
513
2971
64
86
7.96
45.51
1.1
1.1
—
—
—
0
0
555
3406
2.79
44.53
33.6
5.6
1.2
1.2
mmol/l
0.17
535
3037
262
1101
2.99
43.92
3.4
2.4
2.1
2.3
g/l
4.36
248
1007
412
2213
2.66
42.71
31.6
3.7
7.4
7.4
ph
0.67
64
414
268
1188
2.83
40.21
3.4
2.4
12.7
12.2
umol/l
0.53
255
1085
44
43
10.73
39.84
2.1
1.9
1.0
0.8
e9/l
0.35
20
24
565
3701
2.55
36.36
19.7
5.9
10.1
12.3
umol/l
6.05
555
3487
167
599
3.22
36.24
1.4
1.4
—
—
—
0
0
166
596
3.21
35.94
3.6
3.6
99.0
92.4
ng/l
0.31
150
514
196
779
2.97
35.53
8.5
2.5
4.8
9.7
umol/l
6.46
180
692
392
2241
2.38
33.25
8.4
2.6
—
—
—
0
0
101
275
4.03
33.20
2.9
2.8
0.5
0.2
g/l
2.40
62
101
144
504
3.23
32.34
8.2
4.0
0.2
0.7
%
0.41
107
140
35
34
10.69
31.74
5.6
2.4
1943.1
2052.6
ml
0.20
35
27
308
1682
2.30
27.98
7.0
2.5
—
—
—
0
0
478
3161
2.16
26.46
11.7
4.2
—
—
—
0
0
400
2495
2.13
25.48
9.3
3.4
2.3
2.3
mmol/l
4.60
367
2113
105
357
3.21
24.48
2.5
1.8
2.3
2.2
ug/l
0.04
93
304
49
101
5.09
22.74
4.7
6.2
9.4
12.4
mg/l
4.05
42
92
233
1236
2.22
21.84
17.1
4.5
—
—
—
0
0
286
1647
2.11
21.70
33.0
6.1
—
—
—
0
0
26
29
9.22
21.28
1.7
1.9
24.6
18.1
%
0.57
12
13
159
748
2.38
19.61
6.8
3.3
1.1
2.1
mmol/l
2.03
124
583
402
2698
1.92
19.16
3.8
2.7
312.8
154.8
ug/l
5.11
372
2408
86
302
3.05
18.88
6.7
4.5
24.1
25.1
mmol/l
2.15
78
282
17
12
14.43
18.52
1.4
1.3
—
—
—
0
0
318
2002
1.94
18.13
2.1
2.2
2.8
3.2
mg/l
1.93
261
1660
284
1730
1.96
17.78
8.0
3.9
86.9
84.4
%
0.84
278
1685
29
46
6.49
17.65
1.3
1.3
—
—
—
0
0
28
44
6.55
17.19
1.4
1.3
0.2
0.5
g/l
2.64
22
34
28
44
6.55
17.19
1.4
1.3
1.7
2.8
g/l
1.09
21
35
95
371
2.76
17.16
6.4
4.0
—
—
—
0
0
22
7
32.20
17.09
1.3
1.0
—
—
—
0
0
117
508
2.51
17.08
5.9
3.9
7.4
7.4
ph
—
9
63
508
6263
0.54
16.86
4.0
5.4
2.5
2.6
mmol/l
0.80
461
5590
551
4209
1.87
16.51
17.9
4.7
6.5
6.9
mmol/l
4.02
536
3970
117
517
2.46
16.43
5.9
3.9
4.7
5.2
kpa
7.27
107
474
35
72
5.03
16.27
1.1
1.2
—
—
—
0
0
53
151
3.68
16.20
1.3
1.2
—
—
—
0
0
21
7
30.70
16.16
1.3
1.0
—
—
—
0
0
21
7
30.70
16.16
1.3
1.0
—
—
—
0
0
21
7
30.70
16.16
1.3
1.0
—
—
—
0
0
136
650
2.30
15.98
9.0
7.6
—
—
—
0
0
43
108
4.14
15.66
3.0
2.1
34.3
32.3
pg
2.83
43
108
25
41
6.25
14.73
1.3
1.1
—
—
—
0
0
25
42
6.10
14.39
1.3
1.1
—
—
—
0
0
499
6084
0.57
13.98
3.7
4.8
4.3
4.4
mmol/l
1.48
460
5466
34
78
4.50
13.90
1.5
1.7
0.3
0.9
g/l
2.27
26
64
267
1704
1.82
13.85
2.0
1.8
986.9
1183.5
nmol/l
2.66
229
1256
492
6016
0.57
13.84
3.7
4.7
1.3
1.5
mmol/l
9.16
450
5353
17
19
9.11
13.81
1.0
1.1
—
—
—
0
0
372
2620
1.74
13.73
5.3
3.1
2299.7
1821.4
ng/l
1.22
342
2279
15
15
10.16
13.16
1.1
1.3
—
—
—
0
0
232
1442
1.84
12.99
2.9
1.6
1.4
1.3
mg/l
0.17
191
1140
31
70
4.56
12.93
1.2
1.4
265.6
211.4
miu/ml
0.25
11
28
17
21
8.24
12.79
1.0
1.1
—
—
—
0
0
341
2401
1.70
12.21
3.3
3.5
—
—
—
0
0
28
62
4.64
11.96
1.4
1.1
—
—
—
0
0
521
6195
0.59
11.77
5.1
5.1
6.0
6.1
mmol/l
0.89
469
5476
140
760
2.01
11.69
28.6
4.3
—
—
—
0
0
233
1491
1.77
11.66
6.7
4.0
156.8
267.9
ng/l
0.66
206
1288
83
1671
0.44
11.57
1.5
1.6
1.5
1.3
mmol/l
1.74
77
1361
15
18
8.46
11.52
1.1
1.1
—
—
—
0
0
501
5995
0.60
11.29
5.1
6.7
40.4
41.1
mmol/mol
1.19
462
5418
18
28
6.55
11.12
1.9
1.6
755.1
1022.7
u/ml
0.70
18
28
16
22
7.39
11.01
1.1
1.2
—
—
—
0
0
321
2278
1.65
10.84
4.4
3.5
54.8
110.4
e6/l
0.65
272
1810
15
7
21.78
10.70
1.7
1.6
—
—
—
0
0
86
401
2.27
10.60
4.6
3.2
3.5
4.2
e9/l
1.43
67
282
236
1558
1.71
10.41
3.5
3.0
540.9
552.5
mosm/kgh2o
0.43
216
1320
132
741
1.92
9.93
4.0
3.1
259.0
254.8
ng/l
0.03
119
681
177
1098
1.77
9.66
2.0
2.0
—
—
—
0
0
227
1510
1.68
9.64
1.5
1.3
—
—
—
0
0
190
1208
1.74
9.50
3.7
3.2
2.1
2.2
e6/l
0.11
105
712
491
5822
0.63
9.48
3.9
4.2
1.4
1.3
mmol/l
2.98
446
5128
280
1972
1.62
9.48
4.4
3.4
—
—
—
0
0
225
1504
1.67
9.34
6.7
3.2
2.5
2.5
mmol/l
0.46
203
1301
275
1939
1.62
9.22
1.9
1.6
19.0
20.6
nmol/l
0.94
264
1608
140
821
1.84
9.18
1.8
1.8
—
—
—
0
0
53
214
2.57
8.96
4.8
3.5
—
—
—
0
0
14
21
6.76
8.92
2.1
1.3
—
—
—
0
0
100
1740
0.52
8.80
2.4
3.3
—
—
—
0
0
343
2581
1.55
8.55
5.1
4.0
64.9
138.2
e6/l
1.43
278
1928
235
1630
1.61
8.29
3.2
2.7
7.0
4.8
e6/l
2.19
217
1438
71
340
2.19
8.21
1.2
1.3
—
—
—
0
0
285
2072
1.56
8.21
4.4
3.4
0.6
0.5
e6/l
0.11
238
1617
11
14
7.95
8.00
2.2
1.4
—
—
—
0
0
44
172
2.64
7.96
2.7
2.8
1.9
1.8
mg/l
0.20
37
151
45
182
2.55
7.61
1.7
1.3
0.2
0.2
g/l
0.08
40
174
406
3223
1.49
7.59
13.2
11.4
1.4
1.3
inr
0.22
85
879
46
190
2.50
7.46
1.7
1.3
1.1
1.2
g/l
0.33
41
181
128
789
1.73
7.02
2.1
1.4
—
—
—
0
0
80
431
1.94
6.77
9.6
8.9
—
—
—
0
0
10
14
7.22
6.71
1.1
1.0
866.3
1412.2
miu/ml
—
10
14
118
721
1.74
6.67
1.2
1.3
753.3
425.1
titre
0.82
12
161
147
956
1.65
6.59
6.7
6.6
1.1
1.4
mmol/l
0.25
108
727
11
18
6.18
6.44
2.0
2.1
—
—
—
0
0
31
113
2.81
6.44
7.2
2.9
2.7
4.7
e9/l
6.02
31
113
32
119
2.75
6.40
7.4
3.3
51.7
61.2
%
2.84
32
119
21
61
3.50
6.32
1.0
1.1
—
—
—
0
0
597
5214
1.48
6.31
34.6
7.4
74.3
81.0
u/l
2.97
583
4831
145
955
1.62
6.17
6.8
6.5
4.9
5.1
kpa
1.16
133
909
145
956
1.62
6.14
6.7
6.5
11.5
11.7
kpa
0.20
134
910
10
8
12.63
6.09
1.0
1.0
—
—
—
0
0
10
8
12.63
6.09
1.6
1.1
—
—
—
0
0
12
23
5.28
6.02
1.4
1.0
—
—
—
0
0
52
251
2.14
5.94
8.3
5.5
1.3
1.3
mmol/l
0.26
45
221
624
6846
0.67
5.87
83.9
25.6
115.1
132.3
g/l
105.72
608
6680
624
6846
0.67
5.87
83.5
25.5
3.7
4.4
e12/l
123.73
603
6593
624
6845
0.67
5.85
83.3
25.4
96.4
91.8
fl
67.99
610
6682
624
6845
0.67
5.85
83.1
25.4
31.7
30.4
pg
45.73
611
6681
624
6845
0.67
5.85
83.6
25.5
186.9
239.7
e9/l
55.23
605
6616
507
5771
0.70
5.82
4.6
4.7
2.2
2.0
mu/l
0.91
474
5088
390
3180
1.42
5.80
2.7
2.1
86.5
94.1
pmol/l
3.03
280
1620
625
6848
0.68
5.74
83.4
25.5
5.6
6.9
e9/l
31.41
606
6595
283
2182
1.44
5.72
2.8
2.4
55.6
56.9
u/l
0.24
267
2003
132
868
1.62
5.63
6.9
6.7
95.0
95.4
%
0.24
125
834
119
777
1.62
5.22
7.6
7.2
104.4
120.1
g/l
14.46
113
753
5
0
+∞
5.21
10.2
0.0
803.2
—
mg/l
—
5
0
8
6
13.44
5.08
1.0
1.0
—
—
—
0
0
9
9
10.09
5.03
11.1
12.1
5.2
6.4
mmol/l
—
9
9
363
2984
1.38
4.89
5.5
4.2
43.7
53.3
ng/l
0.40
316
2309
608
6647
0.71
4.87
42.2
11.1
26.0
24.3
u/l
1.27
594
6325
345
2816
1.38
4.84
29.1
10.1
0.0
0.0
e9/l
0.04
295
2289
18
480
0.36
4.74
1.3
1.5
—
—
—
0
0
530
4650
1.37
4.62
5.6
4.7
—
—
—
0
0
40
194
2.11
4.57
2.5
1.6
—
—
—
0
0
39
190
2.10
4.41
9.8
5.6
105.3
105.3
mmol/l
0.00
33
173
39
190
2.10
4.41
9.8
5.6
11.6
11.4
mmol/l
0.21
33
173
592
6471
0.72
4.40
43.2
16.9
—
—
—
0
0
15
46
3.30
4.20
1.0
1.2
—
104.0
—
0
10
620
6708
0.73
4.09
66.4
21.0
4.0
4.0
mmol/l
3.28
607
6489
619
6695
0.73
4.03
58.3
20.9
138.7
139.6
mmol/l
12.26
606
6482
547
4876
1.34
3.98
8.2
4.2
38.1
14.7
mm/h
41.56
519
4413
39
199
2.01
3.93
1.4
1.4
233.7
265.9
ug/g
0.50
25
115
69
422
1.69
3.92
7.1
8.9
23.4
24.6
mmol/l
1.39
63
388
521
4620
1.33
3.88
6.1
5.1
21.2
3392.3
e6/l
—
9
85
59
347
1.75
3.86
8.2
4.2
1.6
1.6
%
0.05
53
327
59
348
1.75
3.82
8.2
4.3
1.0
0.9
%
0.25
53
328
33
161
2.09
3.75
1.4
2.3
30.7
34.7
umol/l
0.49
23
128
16
55
2.95
3.75
1.0
1.2
—
—
—
0
0
61
367
1.71
3.69
1.9
2.6
—
15.3
—
0
10
14
46
3.08
3.54
1.9
1.8
—
—
—
0
0
86
574
1.55
3.46
5.4
4.1
—
—
—
0
0
13
42
3.13
3.38
5.1
3.6
—
—
—
0
0
88
594
1.54
3.38
2.1
2.1
127.6
159.7
ug/g
0.55
74
463
187
2355
0.74
3.36
3.2
4.0
21.5
8.8
mg/mmol
2.12
140
1499
195
1550
1.33
3.03
3.6
4.0
—
—
—
0
0
31
562
0.53
3.03
1.4
1.5
—
—
—
0
0
25
121
2.10
2.95
1.1
1.4
—
—
—
0
0
122
1602
0.72
2.82
2.8
3.3
0.9
0.8
ug/l
0.33
94
1136
35
196
1.82
2.75
1.2
1.2
—
—
—
0
0
31
170
1.85
2.62
4.3
4.2
—
—
—
0
0
58
380
1.56
2.58
4.1
2.3
0.6
0.7
%
0.14
58
367
57
372
1.57
2.58
1.2
1.2
—
—
—
0
0
8
213
0.37
2.56
1.1
1.4
—
—
—
0
0
183
2236
0.77
2.55
2.8
3.1
6.7
7.1
mmol/l
0.69
162
1817
427
4724
0.81
2.48
5.2
4.4
—
—
—
0
0
5
8
6.28
2.37
1.0
1.3
—
—
—
0
0
7
18
3.91
2.25
1.3
1.4
—
—
—
0
0
60
412
1.49
2.19
2.6
2.6
—
—
—
0
0
75
542
1.42
2.12
7.0
5.9
24.0
24.3
mmol/l
0.27
69
510
32
513
0.61
2.05
1.5
1.5
—
—
—
0
0
22
119
1.87
1.98
1.4
1.3
1350.2
1393.4
e6/l
0.03
16
82
30
179
1.70
1.97
4.5
4.7
2.4
2.7
mmol/l
0.46
18
122
16
77
2.10
1.97
4.6
3.5
—
—
—
0
0
243
2799
0.82
1.95
3.9
5.5
2.4
3.3
ug/l
1.37
207
2457
35
219
1.62
1.94
4.5
4.3
7.4
7.4
ph
0.42
29
176
36
227
1.61
1.93
3.2
3.2
23.7
24.9
mmol/l
0.94
30
191
22
375
0.58
1.81
1.1
1.3
—
—
—
0
0
13
60
2.18
1.78
1.0
1.1
—
—
—
0
0
138
1674
0.79
1.77
1.6
1.8
457.1
12528563.0
pmol/l
1.08
117
1333
14
68
2.08
1.71
2.1
2.3
0.2
2.1
u/field
—
5
24
7
163
0.42
1.68
1.0
1.1
—
—
—
0
0
151
1802
0.80
1.67
4.6
4.4
0.0
0.0
estimate
0.00
38
566
67
497
1.38
1.67
7.2
8.4
0.8
0.7
%
0.42
67
491
13
62
2.11
1.66
1.2
1.3
—
—
—
0
0
33
213
1.57
1.64
1.3
1.3
—
—
—
0
0
7
26
2.71
1.58
1.1
1.4
—
—
—
0
0
20
114
1.77
1.57
1.1
1.1
—
—
—
0
0
17
92
1.87
1.57
1.3
1.3
—
—
—
0
0
105
843
1.28
1.54
2.1
4.0
4.5
30.3
ug/l
1.83
84
716
58
428
1.38
1.51
2.7
2.9
0.3
0.3
e6/l
0.09
58
421
12
58
2.08
1.49
1.1
1.1
—
—
—
0
0
66
502
1.34
1.43
7.2
8.2
1.3
1.4
%
0.52
66
496
20
118
1.71
1.42
5.1
2.7
—
—
—
0
0
441
4732
0.86
1.42
3.8
3.8
14.6
15.1
pmol/l
3.39
416
4152
5
17
2.95
1.36
1.0
1.1
—
—
—
0
0
5
18
2.79
1.28
1.2
1.1
—
—
—
0
0
22
138
1.61
1.27
1.5
1.5
—
—
—
0
0
23
146
1.59
1.27
1.2
1.3
52.9
62.4
mmol/l
0.67
18
117
34
237
1.45
1.24
2.7
3.1
0.8
0.9
nmol/l
0.51
25
188
137
1164
1.21
1.23
26.2
29.2
1.3
1.4
inr
0.18
22
148
9
168
0.53
1.19
1.2
1.4
—
—
—
0
0
27
182
1.50
1.17
3.0
2.3
—
—
—
0
0
0
35
0.00
1.15
0.0
1.3
—
1.0
—
0
35
0
36
0.00
1.14
0.0
1.3
—
—
—
0
0
11
59
1.88
1.07
1.2
1.2
—
—
—
0
0
23
153
1.52
1.07
1.1
1.2
—
634.0
—
0
5
251
2271
1.15
1.07
2.5
2.2
163.3
248.8
u/l
1.15
237
2120
9
48
1.88
1.00
2.1
2.3
—
—
—
0
0
26
181
1.45
0.99
1.8
1.7
22005.2
18195.3
e6/l
0.17
18
132
10
175
0.57
0.99
1.0
1.2
—
—
—
0
0
471
4960
0.89
0.97
77.6
23.2
329.2
331.1
g/l
4.65
466
4903
0
30
0.00
0.97
0.0
2.3
—
531.5
—
0
25
18
116
1.56
0.97
1.7
1.5
—
—
—
0
0
17
108
1.59
0.97
1.4
1.3
16459.9
87606.7
e6/l
—
8
63
23
157
1.48
0.97
3.2
2.9
—
—
—
0
0
88
736
1.22
0.96
2.4
2.6
6.4
6.2
ug/l
0.03
72
633
0
32
0.00
0.95
0.0
1.6
—
—
—
0
0
0
32
0.00
0.95
0.0
1.2
—
—
—
0
0
17
110
1.56
0.91
1.4
1.3
—
—
—
0
0
9
152
0.59
0.89
1.0
1.1
—
—
—
0
0
18
120
1.51
0.86
4.9
2.7
—
—
—
0
0
151
1694
0.87
0.85
4.0
4.0
—
—
—
0
0
8
45
1.78
0.84
15.0
16.3
—
—
—
0
0
46
573
0.79
0.80
5.4
4.3
—
—
—
0
0
0
27
0.00
0.77
0.0
2.2
—
57847.7
—
0
19
0
28
0.00
0.76
0.0
3.4
—
30.1
—
0
21
15
218
0.68
0.72
26.9
13.0
—
—
—
0
0
5
26
1.93
0.70
1.0
1.1
—
62.5
—
0
6
7
41
1.71
0.70
7.1
4.3
—
26.3
—
0
13
7
41
1.71
0.70
1.4
2.2
—
—
—
0
0
5
27
1.86
0.68
9.6
5.0
—
—
—
0
0
9
59
1.53
0.68
1.1
1.3
5.6
11.2
%
—
9
59
7
118
0.59
0.68
1.6
1.6
—
—
—
0
0
15
103
1.46
0.65
1.6
1.9
87.8
89.2
%
0.25
15
103
5
29
1.73
0.64
1.0
1.1
—
—
—
0
0
480
4985
0.92
0.63
74.3
21.3
15.3
13.9
%
48.99
469
4864
524
5420
0.91
0.62
61.6
19.0
34.2
38.4
%
14.90
333
3283
18
130
1.39
0.61
1.0
1.2
13.2
36.2
e6/l
0.42
13
100
18
130
1.39
0.61
1.1
1.3
17.1
1055.9
e6/l
0.65
13
103
0
20
0.00
0.60
0.0
1.0
—
—
—
0
0
271
2546
1.09
0.59
2.3
2.3
—
—
—
0
0
0
23
0.00
0.58
0.0
2.1
—
—
—
0
0
16
115
1.40
0.57
1.2
1.5
—
—
—
0
0
9
62
1.46
0.53
1.3
1.6
—
—
—
0
0
22
170
1.30
0.52
3.0
2.6
13.4
15.5
%
—
10
85
338
3222
1.08
0.52
5.5
5.6
0.0
0.0
estimate
0.00
52
594
9
64
1.41
0.51
2.6
2.8
—
—
—
0
0
211
2253
0.92
0.51
5.1
4.3
—
—
—
0
0
12
84
1.43
0.49
1.2
1.5
68.7
69.0
%
—
6
58
342
3268
1.08
0.49
3.9
4.2
0.0
0.0
estimate
0.50
51
579
338
3230
1.08
0.48
3.9
4.1
0.0
0.0
estimate
0.00
53
602
14
102
1.38
0.47
1.5
2.5
—
—
—
0
0
135
1463
0.91
0.46
4.3
4.6
1.0
1.0
kg/l
0.95
25
223
7
51
1.38
0.44
1.0
1.0
—
—
—
0
0
100
909
1.11
0.43
1.2
1.2
—
—
—
0
0
5
32
1.57
0.42
1.2
1.0
305.4
308.2
mg/l
—
5
27
18
140
1.29
0.42
2.8
1.8
46.4
59.9
%
1.31
18
140
0
15
0.00
0.41
0.0
6.5
—
—
—
0
0
0
15
0.00
0.41
0.0
1.5
—
—
—
0
0
0
16
0.00
0.41
0.0
1.5
—
—
—
0
0
0
17
0.00
0.40
0.0
1.2
—
—
—
0
0
8
60
1.34
0.40
1.1
1.3
—
—
—
0
0
0
18
0.00
0.40
0.0
1.6
—
—
—
0
0
0
18
0.00
0.40
0.0
1.3
—
—
—
0
0
23
281
0.81
0.40
1.0
1.2
169.8
127.3
iu/ml
—
10
103
10
137
0.73
0.39
1.3
1.3
—
—
—
0
0
622
6332
0.94
0.37
66.3
17.4
22.2
27.4
mg/l
4.40
592
5198
37
319
1.17
0.36
1.9
3.2
14.6
12771.4
u/ml
0.83
31
268
83
898
0.92
0.30
1.2
1.2
11.3
12.3
u/ml
0.03
13
301
8
107
0.75
0.29
1.9
1.7
—
—
—
0
0
20
167
1.20
0.28
2.8
2.4
106.8
126.4
g/l
2.57
14
122
15
123
1.22
0.25
1.2
1.5
2.2
6.7
iu/l
—
5
30
20
170
1.18
0.24
2.6
4.0
22.2
28.7
mg/l
0.72
14
111
36
322
1.12
0.24
3.8
4.2
—
—
—
0
0
7
94
0.74
0.22
1.3
1.5
—
—
—
0
0
5
41
1.22
0.22
1.0
1.0
—
—
—
0
0
33
367
0.90
0.21
2.9
2.9
—
—
—
0
0
0
11
0.00
0.21
0.0
1.1
—
0.3
—
0
6
0
12
0.00
0.21
0.0
1.0
—
10.8
—
0
5
28
314
0.89
0.21
2.0
3.3
1.5
1.4
mmol/l
0.15
28
307
0
13
0.00
0.21
0.0
13.5
—
1002.5
—
0
13
0
13
0.00
0.21
0.0
15.7
—
1828.6
—
0
13
0
13
0.00
0.21
0.0
1.3
—
—
—
0
0
0
14
0.00
0.20
0.0
1.2
—
49.1
—
0
14
25
280
0.89
0.19
2.4
2.0
—
—
—
0
0
34
309
1.10
0.18
1.9
1.2
—
—
—
0
0
11
91
1.21
0.17
1.6
1.9
182.6
212.4
pmol/l
0.31
11
82
7
63
1.11
0.17
1.7
1.3
—
—
—
0
0
5
66
0.76
0.17
1.8
1.5
—
—
—
0
0
8
73
1.10
0.15
1.1
1.3
5.5
49.6
mu/l
—
8
64
119
1146
1.04
0.15
1.2
1.2
1.9
1.5
u/ml
—
5
283
7
87
0.80
0.14
3.0
2.1
—
—
—
0
0
91
944
0.96
0.12
1.2
1.3
35.3
38.3
iu/ml
0.05
27
307
226
2215
1.03
0.11
9.8
3.2
10779.1
281.2
mg/l
13.56
183
1427
26
241
1.08
0.10
4.5
5.1
—
—
—
0
0
5
44
1.14
0.10
1.0
1.2
—
—
—
0
0
87
844
1.03
0.08
1.3
1.3
—
—
—
0
0
11
123
0.89
0.08
1.2
1.1
—
—
—
0
0
43
411
1.05
0.08
4.3
4.1
—
—
—
0
0
72
742
0.97
0.07
1.4
1.3
—
—
—
0
0
8
76
1.05
0.07
1.4
1.3
—
—
—
0
0
49
473
1.04
0.06
3.6
3.5
—
—
—
0
0
22
231
0.95
0.04
1.2
1.1
—
34.2
titre
—
0
5
14
146
0.96
0.00
1.3
1.2
—
2.8
—
0
18
12
122
0.98
0.00
2.4
2.8
—
—
—
0
0
64
641
1.00
0.00
3.6
3.5
—
—
—
0
0
16
163
0.98
0.00
3.0
2.3
—
—
—
0
0
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
0.1
—
0
6
0
6
0.00
0.00
0.0
1.3
—
—
—
0
0
0
9
0.00
0.00
0.0
1.2
—
—
—
0
0
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
0
9
0.00
0.00
0.0
1.7
—
—
—
0
0
0
8
0.00
0.00
0.0
2.0
—
14.1
—
0
8
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
6
60
1.00
0.00
1.2
1.1
—
—
—
0
0
0
7
0.00
0.00
0.0
1.3
—
—
—
0
0
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0

Mortality – FinRegistry

↥

This endpoint is excluded (different definition than used in FinnGen).

Relationships between endpoints

↥

Index endpoint: C3_MYELOMA_MONOCLONAL – Multiple myeloma, Monoclonal gammopathy of undetermined significance (MGUS)

GWS hits: 1

This endpoint is excluded (different definition than used in FinnGen).