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Other nonthrombocytopenic purpura

DOID EFO Endpoint Browser PheWeb

D3_OTHNONTHROMBOCYTOPENPURPURA

Endpoint definition

↥

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — D69.2
  • Hospital discharge: ICD-9 — 2872
  • Cause of death: ICD-10 — D69.2
  • Cause of death: ICD-9 — 2872

2 out of 7 registries used, show all original rules.

305

4. Check minimum number of events

None

305

5. Include endpoints

None

305

6. Filter based on genotype QC (FinnGen only)

305

Control definitions (FinnGen only)

Control exclude
D3_COAGDEF_PURPUR_HAEMORRHAGIC

Extra metadata

Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
D69
Name in latin
Purpura non thrombocytopenica

Case counts by codes

↥

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 2281 1241 1022
Only index persons 1995 1125 870
Unadjusted period prevalence (%)
Whole population 0.03 0.04 0.03
Only index persons 0.04 0.04 0.03
Median age at first event (years)
Whole population 61.62 63.49 59.23
Only index persons 59.44 61.58 56.67

-FinnGen-

Key figures

All Female Male
Number of individuals 305 177 128
Unadjusted period prevalence (%) 0.06 0.06 0.06
Median age at first event (years) 58.97 57.20 61.43

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS (R11)

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
278
Matched controls
2778
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
D69.2
ICD-10 Finland
Other nonthrombocytopenic purpura
4503599627370496.0
323.0
262
*
D69.0
ICD-10 Finland
Allergic purpura
420.7
38.0
37
*
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
7.7
33.8
87
155
L30.9
ICD-10 Finland
Dermatitis, unspecified
4.0
19.5
92
306
H02AB06
ATC
prednisolone; systemic
3.2
19.0
170
917
L95.9
ICD-10 Finland
Vasculitis limited to skin, unspecified
71.5
18.0
20
*
2872B
ICD-9 Finland
Purpura and other haemorrhagic conditions, Other nonthrombocytopenic purpuras
+∞
17.9
17
*
D07AC01
ATC
betamethasone; topical
2.9
15.1
132
664
D69.6
ICD-10 Finland
Thrombocytopenia, unspecified
33.8
12.7
16
5
L81.7
ICD-10 Finland
Pigmented purpuric dermatosis
48.9
12.0
14
*
GD1AA
NOMESCO Finland
Thorax X-ray examination
2.5
12.0
144
836
A46
ICD-10 Finland
Erysipelas
3.4
11.8
63
221
L04AX01
ATC
azathioprine; systemic
6.9
11.8
29
46
C03CA01
ATC
furosemide; systemic
2.7
11.6
103
505
D69.3
ICD-10 Finland
Idiopathic thrombocytopenic purpura
+∞
11.5
11
*
E0000UV
ATC
NA
2.5
11.5
136
776
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
3.4
10.7
55
188
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
2.4
10.3
114
621
D07AB08
ATC
desonide; topical
3.4
9.5
48
161
L95.8
ICD-10 Finland
Other vasculitis limited to skin
+∞
9.4
9
*
R21
ICD-10 Finland
Rash and other nonspecific skin eruption
5.5
9.4
27
53
R50.9
ICD-10 Finland
Fever, unspecified
3.0
9.1
56
217
R60.0
ICD-10 Finland
Localized oedema
3.3
8.9
46
158
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
3.6
8.3
38
118
A02BC02
ATC
pantoprazole; systemic
2.1
7.8
185
1359
XQ848
NOMESCO Finland
Dermatological photography
8.0
7.5
16
21
J01CF05
ATC
flucloxacillin; systemic
5.7
7.4
20
37
XW000
NOMESCO Finland
Bone marrow biopsy
5.6
7.2
20
38
202
Kela drug reimbursment
Connective tissue diseases, rheumatoid arthritis and comparable disease
2.9
6.8
42
161
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
2.9
6.8
42
162
N03AX12
ATC
gabapentin; oral
2.6
6.7
51
222
L17
ICPC
Foot/toe symptom/complaint
2.2
6.7
80
435
SPAT1148
SPAT
Treatment of chronic ulcer or burn
2.6
6.6
48
205
WW200
NOMESCO Finland
Immunization
6.5
6.6
16
26
ZX120
NOMESCO Finland
Intravenous
3.2
6.4
33
113
N08.2*D69.0
ICD-10 Finland
Glomerular disorders in Henoch(-Schönlein) purpura
+∞
6.3
6
*
TQW80
NOMESCO Finland
Local dermatologic skincare
6.5
6.3
15
24
D07AC13
ATC
mometasone; topical
2.1
6.2
87
504
C08CA13
ATC
lercanidipine; oral
2.6
6.2
46
198
J01FF01
ATC
clindamycin; systemic
2.1
6.2
82
466
P01BA02
ATC
hydroxychloroquine; oral
3.1
6.1
32
111

LabWAS

↥
OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
66
105
7.75
41.64
1.2
1.3
—
—
—
0
0
95
329
3.74
23.32
1.4
1.4
1033.7
449.1
titre
0.92
19
70
213
1258
3.30
20.82
9.6
5.3
0.0
0.0
e9/l
0.38
196
1097
211
1253
3.22
20.16
9.6
5.3
0.6
0.6
e9/l
0.76
194
1089
63
183
4.08
19.64
2.3
2.8
66.8
66.1
g/l
0.28
57
162
214
1294
3.19
19.55
9.7
5.6
0.2
0.2
e9/l
0.51
197
1151
211
1291
3.06
18.38
9.7
5.3
1.9
1.9
e9/l
0.14
196
1156
227
1473
3.12
17.26
12.6
8.6
4.4
4.1
e9/l
0.87
208
1304
54
164
3.79
15.64
2.3
2.1
—
—
—
0
0
183
1132
2.54
14.02
9.9
5.5
0.6
0.7
%
0.09
175
1055
186
1162
2.54
13.91
9.9
5.5
2.7
2.8
%
0.17
179
1086
143
792
2.52
13.87
8.7
5.5
—
—
—
0
0
186
1167
2.52
13.70
10.1
5.8
8.7
8.7
%
0.12
179
1097
174
1060
2.49
13.65
6.2
4.3
35.0
35.7
g/l
0.92
166
993
184
1183
2.40
12.34
9.8
5.4
59.1
57.5
%
0.97
176
1112
185
1197
2.39
12.16
10.1
5.6
25.9
27.8
%
1.36
175
1120
23
48
5.10
10.67
1.6
1.4
—
—
—
0
0
113
620
2.31
10.58
3.5
2.7
4870.4
7026.6
umol/l
0.18
102
530
114
634
2.27
10.28
9.6
6.6
—
—
—
0
0
52
203
2.88
9.86
5.1
3.6
—
—
—
0
0
181
1233
2.15
9.58
8.9
6.5
1.2
1.2
mmol/l
0.45
160
1035
22
49
4.76
9.46
2.3
4.3
—
—
—
0
0
239
1831
2.41
9.29
6.6
4.0
16.8
12.0
mm/h
3.88
227
1675
115
666
2.17
9.20
6.0
4.1
—
—
—
0
0
190
1335
2.12
9.07
6.8
5.9
11.6
11.0
umol/l
0.32
181
1264
108
613
2.18
9.07
3.0
2.0
3.1
3.3
mg/l
0.46
97
515
14
22
6.62
8.60
1.9
1.2
—
—
—
0
0
69
331
2.40
8.59
3.6
2.2
20.0
21.9
%
0.60
62
283
126
777
2.06
8.38
4.3
3.2
—
—
—
0
0
126
779
2.05
8.31
6.6
3.7
7.4
7.4
ph
0.09
13
146
164
1121
2.00
8.09
7.4
6.3
1.2
1.2
mmol/l
0.57
153
1008
25
70
3.80
8.03
4.6
3.1
—
—
—
0
0
72
364
2.28
7.90
3.2
2.0
—
—
—
0
0
86
470
2.16
7.78
5.2
3.9
136.8
307.1
ng/l
0.99
77
365
24
67
3.80
7.74
2.7
3.7
48.2
30.2
mg/l
0.94
18
57
24
67
3.80
7.74
2.7
3.6
131.2
150.1
mg/l
0.06
18
57
78
416
2.18
7.48
1.5
1.3
71.9
28.8
iu/ml
0.39
22
145
198
1473
1.98
7.36
5.4
5.0
6.7
6.7
mmol/l
0.10
190
1361
64
320
2.27
7.16
30.1
22.4
1.8
1.3
inr
1.26
12
44
20
52
4.05
7.10
1.7
1.6
—
—
—
0
0
92
532
2.04
7.10
3.9
2.6
3.9
6.3
e6/l
0.84
83
466
101
607
1.99
6.98
5.5
3.8
85.8
90.7
%
0.88
101
595
159
1112
1.90
6.98
14.3
9.4
0.0
0.0
e9/l
0.60
133
924
57
278
2.29
6.74
2.6
1.6
—
—
—
0
0
47
212
2.44
6.62
7.1
9.0
—
—
—
0
0
56
275
2.27
6.51
2.7
2.5
2.0
1.7
%
1.23
50
245
97
592
1.94
6.32
6.8
4.3
—
—
—
0
0
238
1936
2.04
6.27
11.9
7.0
83.2
77.2
u/l
1.23
228
1805
50
241
2.29
6.06
7.5
3.9
—
—
—
0
0
110
708
1.87
6.05
5.3
3.8
18.5
11.4
mg/mmol
0.46
85
431
14
31
4.69
6.05
2.0
1.5
—
—
—
0
0
217
1728
1.89
5.86
7.1
4.2
—
—
—
0
0
43
198
2.36
5.78
3.1
2.5
77.2
69.2
e9/l
0.80
31
158
84
502
1.93
5.76
2.0
1.4
2.8
2.5
g/l
0.62
67
313
54
275
2.17
5.72
1.9
1.5
—
—
—
0
0
79
465
1.94
5.65
2.8
2.9
2.5
2.5
mmol/l
1.04
71
404
78
466
1.91
5.31
1.9
1.7
1113.2
1234.8
nmol/l
0.61
62
346
139
992
1.74
5.24
9.4
7.9
1.3
1.2
inr
0.26
36
299
106
702
1.78
5.17
4.9
3.0
0.3
0.4
e6/l
0.37
85
527
113
765
1.76
5.10
2.1
2.1
152.6
206.9
u/l
0.48
107
721
53
282
2.06
5.00
3.2
2.7
9.2
6.7
umol/l
0.36
48
243
24
89
2.84
4.97
1.5
2.9
19.5
22.1
s
1.71
16
81
101
667
1.77
4.94
4.4
3.0
116.0
169.3
mg/l
0.21
79
424
86
543
1.81
4.88
1.9
1.9
1.6
1.1
mg/l
0.42
67
430
59
330
1.98
4.85
5.7
6.0
103.4
104.0
mmol/l
0.53
59
318
75
459
1.84
4.69
2.1
1.7
—
—
—
0
0
112
773
1.71
4.63
5.1
3.1
75.9
128.3
e6/l
0.22
91
595
101
678
1.73
4.62
4.7
2.9
—
—
—
0
0
105
715
1.71
4.55
5.0
2.9
6.5
7.6
mmol/l
1.86
96
587
89
579
1.76
4.53
6.5
3.8
—
—
—
0
0
36
173
2.23
4.38
1.6
1.4
—
—
—
0
0
79
501
1.78
4.37
4.0
2.9
508.7
563.7
mosm/kgh2o
1.31
66
425
123
900
1.61
3.92
6.1
3.6
51.0
78.7
e6/l
0.44
99
641
111
792
1.63
3.92
2.7
2.3
61.3
56.9
u/l
0.21
104
729
113
816
1.61
3.78
3.0
3.3
2.4
2.4
mmol/l
0.15
103
710
28
130
2.27
3.71
5.2
2.8
1.1
1.3
%
1.02
28
130
30
144
2.20
3.68
1.6
1.2
258.3
299.4
u/ml
0.06
30
127
54
321
1.83
3.67
1.4
1.4
—
—
—
0
0
207
1733
1.61
3.61
4.8
3.8
—
—
—
0
0
219
1861
1.63
3.56
4.3
3.9
14.6
14.8
pmol/l
0.50
207
1658
132
1000
1.56
3.55
2.4
1.9
92.2
94.5
pmol/l
0.21
80
483
13
41
3.27
3.54
1.2
1.4
301.7
252.2
u/ml
—
6
25
49
286
1.85
3.52
3.4
9.4
0.5
1.4
mmol/l
0.81
42
228
63
397
1.74
3.52
1.6
1.3
5.2
14.2
u/ml
1.01
24
153
12
37
3.34
3.38
2.3
1.5
—
—
—
0
0
60
378
1.73
3.35
1.9
1.6
—
—
—
0
0
253
2246
1.74
3.31
5.5
4.7
1.9
1.9
mu/l
0.43
242
2024
127
966
1.54
3.30
4.9
3.9
55.7
33.1
ng/l
0.61
101
686
7
11
6.48
3.20
1.3
1.3
164.6
111.0
iu/ml
—
7
11
13
45
2.97
3.06
1.6
1.3
—
—
—
0
0
47
284
1.77
3.02
3.5
9.3
5.1
5.2
kpa
0.21
47
271
47
284
1.77
3.02
3.5
9.3
10.7
12.0
kpa
1.58
47
271
155
1250
1.49
2.95
6.0
3.8
0.0
0.0
estimate
0.00
28
256
157
1271
1.48
2.92
6.0
3.9
0.0
0.0
estimate
0.00
28
249
272
2490
1.85
2.88
28.9
13.8
24.1
23.0
mg/l
0.24
240
1962
12
42
2.93
2.78
1.7
1.5
—
—
—
0
0
155
1261
1.47
2.76
7.8
5.2
0.0
0.0
estimate
0.00
29
255
38
224
1.80
2.66
3.5
2.5
6.9
7.2
ug/l
0.03
32
195
13
49
2.73
2.66
2.5
2.5
—
—
—
0
0
31
172
1.89
2.62
2.5
7.3
—
—
—
0
0
5
7
7.24
2.56
1.2
1.0
—
—
—
0
0
76
544
1.53
2.51
6.7
4.3
1.0
1.0
kg/l
—
9
68
102
780
1.46
2.44
2.9
2.2
—
—
—
0
0
10
34
3.01
2.43
2.0
1.3
28.6
34.0
g/l
—
10
29
7
17
4.19
2.37
1.4
1.1
—
—
—
0
0
39
240
1.72
2.37
3.2
9.5
120.9
122.0
g/l
0.15
39
229
33
195
1.78
2.30
5.4
4.2
0.2
0.2
%
0.14
11
51
35
211
1.74
2.29
5.2
4.1
0.5
1.1
%
1.42
13
60
29
165
1.84
2.29
2.1
2.4
—
6.8
—
0
6
8
23
3.54
2.28
1.3
1.2
—
—
—
0
0
8
24
3.39
2.19
1.5
2.5
—
—
—
0
0
10
37
2.76
2.12
1.0
1.2
—
—
—
0
0
15
69
2.23
2.08
1.3
1.3
—
—
—
0
0
8
26
3.13
2.03
1.5
2.5
—
—
—
0
0
15
70
2.20
2.02
1.8
1.4
272.1
311.4
ug/g
—
9
43
7
21
3.39
1.97
1.3
1.2
—
—
—
0
0
8
27
3.01
1.95
1.1
1.1
—
—
—
0
0
13
58
2.30
1.93
2.1
2.0
127.6
132.5
g/l
—
8
41
11
46
2.44
1.87
1.6
1.2
—
—
—
0
0
30
184
1.70
1.87
4.7
4.2
0.6
0.6
%
—
7
39
20
108
1.91
1.86
6.5
4.6
—
—
—
0
0
18
95
1.95
1.79
1.4
1.2
—
—
—
0
0
11
229
0.46
1.79
1.3
1.4
—
—
—
0
0
72
544
1.42
1.79
1.3
1.2
1.6
1.0
u/ml
0.30
24
153
35
227
1.61
1.77
1.9
1.5
—
—
—
0
0
45
310
1.53
1.77
3.0
2.2
260.9
128.5
ug/g
0.55
40
244
121
1001
1.35
1.73
2.8
2.1
—
—
—
0
0
47
330
1.50
1.70
1.1
1.2
—
—
—
0
0
6
20
3.04
1.59
1.2
1.1
—
—
—
0
0
87
695
1.35
1.54
6.9
4.2
0.0
0.0
estimate
0.00
26
253
7
27
2.63
1.52
1.3
1.0
—
—
—
0
0
6
21
2.89
1.51
1.8
1.1
—
—
—
0
0
25
157
1.65
1.46
1.5
1.3
—
—
—
0
0
76
600
1.36
1.45
1.6
1.5
19.9
21.4
nmol/l
0.37
66
493
135
1168
1.28
1.32
4.6
4.0
—
—
—
0
0
17
99
1.76
1.30
3.9
3.5
—
—
—
0
0
28
187
1.55
1.29
5.7
4.3
0.0
0.2
%
—
6
45
8
35
2.32
1.28
1.1
1.1
—
—
—
0
0
6
25
2.43
1.25
2.5
2.6
—
—
—
0
0
5
20
2.52
1.15
1.0
1.2
—
—
—
0
0
5
20
2.52
1.15
1.0
2.4
—
—
—
0
0
15
88
1.74
1.13
13.9
10.7
—
—
—
0
0
7
31
2.29
1.11
2.3
2.2
—
—
—
0
0
270
2579
1.41
1.11
22.4
12.9
—
—
—
0
0
5
21
2.40
1.09
1.2
1.4
—
—
—
0
0
7
32
2.21
1.08
1.3
1.1
—
—
—
0
0
19
121
1.61
1.08
2.8
14.5
—
—
—
0
0
10
52
1.95
1.07
5.0
3.4
—
—
—
0
0
284
2743
1.51
1.03
39.8
20.3
7.1
6.7
e9/l
1.68
279
2669
252
2389
1.32
1.03
5.3
4.5
6.1
6.0
mmol/l
0.84
241
2170
13
76
1.74
1.00
1.4
1.1
—
—
—
0
0
10
54
1.88
0.97
2.9
2.7
—
—
—
0
0
6
27
2.25
0.94
2.0
1.3
—
—
—
0
0
14
86
1.66
0.92
1.9
2.9
—
—
—
0
0
6
28
2.17
0.92
1.0
1.6
—
—
—
0
0
6
28
2.17
0.92
1.2
1.2
—
—
—
0
0
62
508
1.28
0.92
1.6
1.7
478.4
461.8
pmol/l
0.16
52
418
257
2454
1.30
0.90
5.7
4.9
2.4
2.7
mmol/l
6.25
243
2246
14
87
1.64
0.89
1.5
1.6
—
—
—
0
0
6
30
2.02
0.87
3.2
1.5
32.8
33.0
pg
—
6
30
24
171
1.44
0.86
1.7
1.4
—
—
—
0
0
8
137
0.57
0.85
1.6
1.4
—
—
—
0
0
8
45
1.80
0.85
5.0
3.0
4.2
4.5
e9/l
—
8
45
24
172
1.43
0.84
5.3
9.5
24.5
24.7
mmol/l
0.13
24
159
8
46
1.76
0.83
5.0
3.4
61.5
58.2
%
—
8
46
13
81
1.63
0.82
3.4
3.1
0.2
0.1
g/l
—
7
29
18
123
1.49
0.79
2.6
2.5
—
—
—
0
0
0
24
0.00
0.79
0.0
1.4
—
—
—
0
0
8
48
1.68
0.79
1.8
2.4
39.7
36.5
umol/l
—
8
40
73
622
1.23
0.78
2.0
1.7
1.3
1.4
mmol/l
0.17
65
511
15
99
1.54
0.77
2.0
1.9
—
—
—
0
0
14
91
1.56
0.76
3.6
3.9
3.8
3.9
mmol/l
0.65
14
80
28
212
1.35
0.73
5.7
3.6
—
—
—
0
0
5
25
2.02
0.73
1.4
1.1
—
—
—
0
0
9
57
1.60
0.71
1.2
1.2
—
—
—
0
0
9
58
1.57
0.70
6.0
3.0
2.7
2.3
mmol/l
—
9
38
5
27
1.87
0.68
1.4
1.3
—
—
—
0
0
11
70
1.59
0.66
1.3
1.3
123.6
276.2
miu/ml
—
5
38
248
2382
1.22
0.66
5.0
4.4
1.4
1.5
mmol/l
1.01
237
2177
23
173
1.36
0.64
1.1
1.2
—
—
—
0
0
249
2397
1.21
0.62
5.1
4.4
4.3
4.6
mmol/l
6.09
239
2210
0
23
0.00
0.58
0.0
3.0
—
—
—
0
0
236
2265
1.19
0.58
7.2
5.7
41.4
39.9
mmol/mol
1.43
224
2113
8
54
1.49
0.57
7.3
3.1
7.7
7.3
mmol/l
—
8
54
15
107
1.42
0.56
1.1
1.1
—
—
—
0
0
6
37
1.63
0.56
1.2
1.6
—
—
—
0
0
28
224
1.28
0.53
1.6
1.5
—
—
—
0
0
64
719
0.86
0.46
1.5
1.4
—
—
—
0
0
78
703
1.15
0.45
4.9
3.9
—
—
—
0
0
32
267
1.22
0.44
3.2
4.5
3.5
47.7
ug/l
0.86
22
222
0
15
0.00
0.41
0.0
1.0
—
—
—
0
0
0
15
0.00
0.41
0.0
13.6
—
1348.1
—
0
15
0
15
0.00
0.41
0.0
12.1
—
758.6
—
0
15
0
17
0.00
0.41
0.0
1.6
—
—
—
0
0
5
36
1.40
0.38
8.2
3.0
—
—
—
0
0
5
36
1.40
0.38
8.2
3.0
104.4
106.1
mmol/l
—
5
36
5
36
1.40
0.38
8.2
3.0
4.1
4.0
mmol/l
—
5
36
36
310
1.18
0.37
1.5
1.3
—
—
—
0
0
5
37
1.36
0.37
1.8
2.7
6.4
3.4
umol/l
—
5
26
5
37
1.36
0.37
1.0
1.1
—
—
—
0
0
5
37
1.36
0.37
1.0
1.1
—
—
—
0
0
79
856
0.90
0.34
2.7
2.9
—
—
—
0
0
6
47
1.28
0.32
1.0
1.1
—
—
—
0
0
6
47
1.28
0.32
1.3
1.7
2.0
3.2
e6/l
—
6
37
6
47
1.28
0.32
1.3
1.8
159.5
224.6
e6/l
—
6
39
17
138
1.25
0.31
3.1
3.3
4.6
4.5
pmol/l
0.08
17
117
7
56
1.26
0.29
2.6
2.0
—
—
—
0
0
33
289
1.16
0.29
1.8
1.3
—
—
—
0
0
12
95
1.27
0.26
1.2
1.1
—
—
—
0
0
18
212
0.84
0.25
1.4
1.4
—
—
—
0
0
236
2310
1.10
0.24
4.5
4.0
1.3
1.3
mmol/l
0.11
221
2103
11
136
0.80
0.23
3.6
2.3
33.7
55.8
u/ml
0.49
11
129
16
134
1.20
0.23
5.7
3.7
—
—
—
0
0
5
38
1.32
0.23
1.0
1.3
—
—
—
0
0
5
40
1.25
0.22
1.8
1.4
—
—
—
0
0
0
11
0.00
0.21
0.0
1.1
—
—
—
0
0
0
11
0.00
0.21
0.0
1.3
—
—
—
0
0
0
11
0.00
0.21
0.0
1.1
—
0.2
—
0
6
0
11
0.00
0.21
0.0
1.0
—
0.3
—
0
5
0
11
0.00
0.21
0.0
2.5
—
—
—
0
0
0
14
0.00
0.20
0.0
1.3
—
—
—
0
0
25
222
1.14
0.20
5.5
3.9
—
—
—
0
0
79
748
1.08
0.19
5.3
4.9
2.4
2.5
ug/l
0.03
74
660
227
2234
1.06
0.15
29.2
14.9
39.9
40.0
%
0.03
148
1616
25
272
0.91
0.12
1.6
1.8
—
—
—
0
0
5
45
1.11
0.10
1.4
1.2
—
—
—
0
0
6
71
0.84
0.07
1.2
1.3
—
—
—
0
0
7
81
0.86
0.07
1.6
1.4
—
—
—
0
0
7
81
0.86
0.07
1.6
1.4
—
—
—
0
0
7
81
0.86
0.07
1.6
1.4
—
—
—
0
0
18
168
1.08
0.06
4.1
3.0
—
—
—
0
0
46
446
1.04
0.05
3.2
3.0
0.9
0.7
ug/l
0.27
37
297
14
148
0.94
0.02
1.2
1.3
—
—
—
0
0
24
232
1.04
0.02
1.8
1.7
—
—
—
0
0
71
708
1.00
0.00
4.5
3.5
—
—
—
0
0
11
105
1.05
0.00
1.1
1.8
—
—
—
0
0
17
166
1.03
0.00
1.3
1.2
123.5
156.3
iu/ml
—
6
59
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
0
6
0.00
0.00
0.0
3.8
—
—
—
0
0
0
5
0.00
0.00
0.0
2.8
—
—
—
0
0
5
49
1.02
0.00
2.2
2.9
—
—
—
0
0
7
75
0.93
0.00
1.6
1.4
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
0.00
0.0
2.3
—
1.4
—
0
6
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
19.2
—
0
6
7
77
0.91
0.00
8.1
4.7
—
—
—
0
0
6
65
0.92
0.00
1.2
1.1
—
—
—
0
0
6
65
0.92
0.00
1.7
1.4
—
—
—
0
0
0
5
0.00
0.00
0.0
8.4
—
—
—
0
0
7
79
0.88
0.00
1.6
1.4
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.5
—
—
—
0
0
0
5
0.00
0.00
0.0
1.4
—
37.2
—
0
5

Mortality – FinRegistry

↥

Association

Association between endpoint D3_OTHNONTHROMBOCYTOPENPURPURA and mortality.

Females

Parameter HR [95% CI] p-value
D3_OTHNONTHROMBOCYTOPENPURPURA 1.597 [1.33, 1.92] < 0.001
Birth year 0.993 [0.98, 1.0] 0.101

During the follow-up period (1.1.1998 — 31.12.2019), 289 out of 1034 females with D3_OTHNONTHROMBOCYTOPENPURPURA died.

Males

Parameter HR [95% CI] p-value
D3_OTHNONTHROMBOCYTOPENPURPURA 2.141 [1.7, 2.7] < 0.001
Birth year 0.99 [0.98, 1.0] 0.028

During the follow-up period (1.1.1998 — 31.12.2019), 268 out of 813 males with D3_OTHNONTHROMBOCYTOPENPURPURA died.

Mortality risk

Mortality risk for people of age

years, who have D3_OTHNONTHROMBOCYTOPENPURPURA.

N-year risk Females Males
1 0.141% 0.389%
5 0.854% 2.614%
10 2.273% 6.654%
15 4.128% 12.93%
20 7.356% 21.529%

Relationships between endpoints

↥

Index endpoint: D3_OTHNONTHROMBOCYTOPENPURPURA – Other nonthrombocytopenic purpura

GWS hits: 1

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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