erythema multiforme: Erythema multiforme (EM) refers to a group ofhypersensitivity disorders characterized by symmetric red, patchy lesions, primarily on the arms and legs. The cause is unknown, but EM frequently occurs in association with herpes simplex virus , suggesting an immunologic process initiated by the virus. In half of the cases, the triggering agents appear to be medications, including anticonvulsants, sulfonamides, nonsteroidal anti-inflammatory drugs, and other antibiotics. In addition, some cases appear to be associated with infectious organisms such as Mycoplasma pneumoniae and many viral agents. Erythema multiforme is the mildest of three skin disorders that are often discussed in relation to each other. It is generally the mildest of the three. More severe is Stevens-Johnson syndrome . The most severe of the three is toxic epidermal necrolysis (TEN).
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
519972 |
1. Apply sex-specific ruleNone |
519972 |
2. Check conditionsNone |
519972 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
885 |
4. Check minimum number of eventsNone |
885 |
5. Include endpointsNone |
885 |
6. Filter based on genotype QC (FinnGen only) |
863 |
Control definitions (FinnGen only)
- Control exclude
- L12_URTICARIAERYTHEMA
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- L50-L54
- Name in latin
- Erythema multiforme
Similar endpoints
↥List of similar endpoints to
Erythema multiforme
based on the number of shared cases.
Similar with more cases:
- Urticaria and erythema
- Diseases of the skin and subcutaneous tissue
- Any event in hilmo or specialist outpatient
- Any prescribed medicine buy
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 7231 | 3832 | 3367 |
| Only index persons | 6249 | 3374 | 2875 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.10 | 0.11 | 0.09 |
| Only index persons | 0.12 | 0.12 | 0.11 |
| Median age at first event (years) | |||
| Whole population | 43.65 | 47.82 | 38.77 |
| Only index persons | 42.72 | 46.91 | 37.82 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 863 | 528 | 335 |
| Unadjusted period prevalence (%) | 0.17 | 0.19 | 0.15 |
| Median age at first event (years) | 49.39 | 45.85 | 54.98 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 885
- Matched controls
- 8850
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
L51.9
ICD-10 Finland
Erythema multiforme, unspecified
5154.8
307.7
342
*
L51.0
ICD-10 Finland
Nonbullous erythema multiforme
+∞
200.9
185
*
L51.8
ICD-10 Finland
Other erythema multiforme
+∞
149.3
139
*
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
7.1
123.8
220
394
L51.1
ICD-10 Finland
Bullous erythema multiforme
+∞
121.7
114
*
H02AB06
ATC
prednisolone; systemic
4.1
88.4
600
2982
6951A
ICD-9 Finland
Erythematous conditions, Erythema multiforme[ERYTHEMA MULTIFORME]
+∞
72.9
69
*
L27.0
ICD-10 Finland
Generalized skin eruption due to drugs and medicaments
18.6
69.3
56
32
L51.19
ICD-10 Finland
Other bullous erythema multiforme
+∞
61.2
58
*
L30.9
ICD-10 Finland
Dermatitis, unspecified
3.4
56.2
273
1033
L50.9
ICD-10 Finland
Urticaria, unspecified
10.3
52.4
60
62
L51.10
ICD-10 Finland
Stevens-Johnson syndrome
+∞
49.4
47
*
D07AC01
ATC
betamethasone; topical
2.7
44.6
402
2091
Z01.5
ICD-10 Finland
Diagnostic skin and sensitization tests
3.8
39.7
136
404
D07AB08
ATC
desonide; topical
3.4
38.1
154
510
R21
ICD-10 Finland
Rash and other nonspecific skin eruption
4.8
32.3
76
169
P01BA02
ATC
hydroxychloroquine; oral
3.5
30.5
117
372
L04AX01
ATC
azathioprine; systemic
4.9
30.4
69
149
69510
ICD-8 Finland
Erythematous condition, Eetodermosis multiformis (syndroma Stevens-Johnson)
+∞
28.3
27
*
J05AB01
ATC
aciclovir; systemic
2.4
28.3
248
1225
R06AE07
ATC
cetirizine; oral
2.2
28.2
443
2785
TQW80
NOMESCO Finland
Local dermatologic skincare
6.4
26.5
45
74
L50.0
ICD-10 Finland
Allergic urticaria
9.7
26.3
31
33
H02AB07
ATC
prednisone; oral
2.7
25.9
165
697
L51
ICD-10 Finland
Erythema multiforme
59.9
25.1
29
5
E0000UV, ,
ATC
2.0
23.6
403
2564
J05AB11
ATC
valaciclovir; oral
2.5
23.0
168
756
E000001, ,
ATC
2.3
22.7
212
1065
D07AB02
ATC
hydrocortisone butyrate; topical
2.1
22.2
299
1733
GD1AA
NOMESCO Finland
Thorax X-ray examination
2.0
21.5
423
2802
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
2.0
21.2
324
1962
XQ802
NOMESCO Finland
Epicutan test
4.2
20.8
57
143
R50.9
ICD-10 Finland
Fever, unspecified
2.4
20.4
165
775
L50.8
ICD-10 Finland
Other urticaria
27.8
20.1
27
10
D07AC13
ATC
mometasone; topical
2.0
19.9
276
1606
202
Kela drug reimbursment
Connective tissue diseases, rheumatoid arthritis and comparable disease
2.6
19.8
126
529
L04AA06
ATC
mycophenolic acid; systemic
6.3
19.0
32
52
6951B
ICD-9 Finland
Erythematous conditions, Erythema multiforme[SYNDROMA STEVENS-JOHNSON]
+∞
17.8
17
*
L51.2
ICD-10 Finland
Toxic epidermal necrolysis [Lyell]
+∞
17.8
17
*
D07BB04
ATC
hydrocortisone butyrate and antiseptics; topical
2.4
17.7
140
649
D07AA02
ATC
hydrocortisone; topical
2.3
16.9
152
743
T78.4
ICD-10 Finland
Allergy, unspecified
3.7
16.7
53
148
L04AX03
ATC
methotrexate; systemic
2.5
16.4
107
453
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
3.3
15.6
60
190
XQ848
NOMESCO Finland
Dermatological photography
4.3
15.4
40
96
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
2.3
15.3
132
634
L01BA01
ATC
methotrexate; systemic
3.8
14.9
46
126
K12.10
ICD-10 Finland
Stomatitis NOS
15.7
14.5
23
15
J01FF01
ATC
clindamycin; systemic
1.9
14.4
252
1559
R06AX27
ATC
desloratadine; oral
1.8
14.0
261
1646
J01MA12
ATC
levofloxacin; systemic
2.0
13.5
172
956
NK4XE
NOMESCO Finland
Joint ultrasound examination not elsewhere classified
2.7
13.0
75
298
H02AB09
ATC
hydrocortisone; systemic
4.2
12.6
33
80
ZXD31
NOMESCO Finland
Major difficulties in performing procedure
3.6
12.2
40
114
M05BA04
ATC
alendronic acid; oral
2.4
12.2
85
370
L04AD01
ATC
ciclosporin; systemic
5.0
12.2
26
53
H02AB04
ATC
methylprednisolone; systemic
2.1
12.2
135
712
J04BA02
ATC
dapsone; oral
18.3
12.1
18
10
M32.9
ICD-10 Finland
Systemic lupus erythematosus, unspecified
11.9
11.9
21
18
XQ800
NOMESCO Finland
Prick test
2.6
11.8
72
295
D07AD01
ATC
clobetasol; topical
2.0
11.8
151
839
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
2.2
11.7
107
524
Z01.8
ICD-10 Finland
Other specified special examinations
1.8
11.5
202
1243
M35.0
ICD-10 Finland
Sicca syndrome [Sjögren]
4.3
11.3
29
69
A07AA02
ATC
nystatin; oral
2.7
11.3
63
247
D07BA04
ATC
hydrocortisone and antiseptics; topical
2.2
11.2
95
451
J01DB01
ATC
cefalexin; oral
1.8
11.2
718
6203
N05CF01
ATC
zopiclone; oral
1.7
11.1
282
1921
L40.0
ICD-10 Finland
Psoriasis vulgaris
3.3
11.0
42
133
L12.0
ICD-10 Finland
Bullous pemphigoid
12.1
10.9
19
16
J01MA02
ATC
ciprofloxacin; systemic
1.6
10.7
324
2305
Y57
ICD-10 Finland
Adverse effects in the therapeutic use of other and unspecified drugs and medicaments
4.3
10.6
27
64
L13.9
ICD-10 Finland
Bullous disorder, unspecified
14.4
10.5
17
12
D05BB02
ATC
acitretin; oral
4.3
10.1
26
62
F60.30
ICD-10 Finland
Emotionally unstable personality disorder, impulsive
4.5
10.1
24
54
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
2.2
10.1
88
423
J01FA06
ATC
roxithromycin; oral
1.6
10.0
342
2496
D69.0
ICD-10 Finland
Allergic purpura
12.4
9.9
17
14
D01BA02
ATC
terbinafine; oral
1.7
9.8
215
1402
A02BC02
ATC
pantoprazole; systemic
1.6
9.7
565
4652
B00.10
ICD-10 Finland
Herpes simplex facialis
7.5
9.7
22
30
R06AE09
ATC
levocetirizine; oral
1.9
9.7
129
723
L93.1
ICD-10 Finland
Subacute cutaneous lupus erythematosus
55.6
9.7
11
*
SPAT1263
SPAT
Sampling
1.6
9.6
355
2632
D01AC20
ATC
imidazoles/triazoles in combination with corticosteroids; topical
1.7
9.4
197
1267
L50.3
ICD-10 Finland
Dermatographic urticaria
12.5
9.4
16
13
L27.1
ICD-10 Finland
Localized skin eruption due to drugs and medicaments
12.5
9.4
16
13
T88.7
ICD-10 Finland
Unspecified adverse effect of drug or medicament
4.4
9.4
23
53
M32.8
ICD-10 Finland
Other forms of systemic lupus erythematosus
22.0
9.4
13
6
J01DA01
ATC
[U] cefalexin
1.6
9.3
527
4292
N05BB01
ATC
hydroxyzine; systemic
2.4
9.3
64
277
D02AX
ATC
Other emollients and protectives
3.3
9.1
34
106
281
Kela drug reimbursment
Abatacept, adalimumab, anakinra, certolizumab pegol, etanercept, golimumab, infliximab, ixekizumab, sarilumab, secukinumab and tocilizumab
3.4
9.0
32
97
N02AX02
ATC
tramadol; systemic, rectal
1.5
8.8
357
2691
TNX10
NOMESCO Finland
Arthrocentesis, unspecified region, unspecified region
2.3
8.8
65
291
DM1AA
NOMESCO Finland
Paranasal sinuses X-ray examination without contrast
3.1
8.8
36
119
M35.9
ICD-10 Finland
Systemic involvement of connective tissue, unspecified
7.3
8.8
20
28
H04.10
ICD-10 Finland
Dry eye syndrome
2.0
8.7
99
525
L04AA13
ATC
[U] leflunomide
3.5
8.7
29
84
J01.0
ICD-10 Finland
Acute maxillary sinusitis
1.6
8.6
211
1413
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
2.1
8.5
85
430
R03AC02
ATC
salbutamol; inhalant
1.5
8.5
473
3807
L12.9
ICD-10 Finland
Pemphigoid, unspecified
20.2
8.5
12
6
A46
ICD-10 Finland
Erysipelas
1.9
8.5
117
664
J01MA14
ATC
moxifloxacin; systemic
2.1
8.4
83
418
M06.9
ICD-10 Finland
Rheumatoid arthritis, unspecified
3.2
8.4
32
101
C03CA01
ATC
furosemide; systemic
1.6
8.4
229
1571
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
2.0
8.4
87
447
M14.8*L51.9
ICD-10 Finland
Arthropathy in erythema: multiforme
+∞
8.3
8
*
A03
ICPC
Fever
1.7
8.3
152
938
L04AB04
ATC
adalimumab; parenteral
3.6
8.2
26
73
B00.11
ICD-10 Finland
Herpes simplex labialis
4.1
8.1
22
55
A49.9
ICD-10 Finland
Bacterial infection, unspecified
2.0
8.1
95
511
N03AX16
ATC
[U] pregabalin
1.6
8.1
195
1298
K12.18
ICD-10 Finland
Other forms of stomatitis
10.2
8.0
15
15
J01AA02
ATC
doxycycline; systemic
1.6
8.0
641
5541
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
1.9
8.0
115
660
A01AB09
ATC
miconazole; local oral
2.1
8.0
80
406
J18.9
ICD-10 Finland
Pneumonia, unspecified
1.6
7.9
202
1361
L98.4
ICD-10 Finland
Chronic ulcer of skin, not elsewhere classified
4.0
7.9
22
56
ND2BA
NOMESCO Finland
Hand and fingers extensive X-ray examination
3.6
7.9
25
70
NK6QA
NOMESCO Finland
Measurement of bone density from two or more locations with X-ray
2.3
7.8
59
267
GD1DD
NOMESCO Finland
High resolution CT examination of lungs
2.5
7.8
47
192
AA1AD
NOMESCO Finland
CT of head and brain
1.6
7.7
209
1428
313
Kela drug reimbursment
Abatacept, adalimumab, anakinra, certolizumab pegol, etanercept, golimumab, infliximab, ixekizumab, sarilumab, secukinumab, tocilizumab and ustekinumab (rheumatoid diseases)
3.1
7.6
31
102
S29
ICPC
Skin symptom/complaint other
1.7
7.6
154
978
A02BC03
ATC
lansoprazole; oral
1.6
7.6
236
1667
SBB00
NOMESCO Finland
Clinical photography of mouth and teeth
2.9
7.4
34
120
S18
ICPC
Laceration/cut
1.5
7.4
367
2860
SBA00
NOMESCO Finland
Microbiological examinations
3.4
7.3
26
79
D06AX01
ATC
fusidic acid; topical
2.0
7.3
85
456
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
1.7
7.2
130
799
NA3BG
NOMESCO Finland
Lumbar spine MRI examination with high intensity magnet
1.9
7.2
86
465
WXQ27
NOMESCO Finland
UVB narrow spectrum light therapy
6.6
7.1
17
26
L04AA01
ATC
[U] ciclosporin
6.1
7.1
18
30
L95.9
ICD-10 Finland
Vasculitis limited to skin, unspecified
10.1
7.0
13
13
JN3AA
NOMESCO Finland
Abdominal X-ray examination without contrast
2.7
7.0
38
147
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
1.7
6.8
132
826
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.5
6.8
296
2236
L52
ICD-10 Finland
Erythema nodosum
11.0
6.8
12
11
TND11
NOMESCO Finland
Injection of diagnostic or therapeutic substance in joint, wrist or hand
5.7
6.8
18
32
7100A
ICD-9 Finland
Diffuse diseases of connective tissue, Systemic lupus erythematosus
40.4
6.8
8
*
S21
ICPC
Skin texture symptom/complaint
1.7
6.7
115
696
N03AX14
ATC
levetiracetam; systemic
3.0
6.7
28
94
D07BC01
ATC
betamethasone and antiseptics; topical
1.8
6.7
96
551
J02AC01
ATC
fluconazole; systemic
1.5
6.7
313
2399
ZX120
NOMESCO Finland
Intravenous
1.9
6.6
81
441
SPAT1148
SPAT
Treatment of chronic ulcer or burn
1.8
6.6
106
629
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
1.4
6.6
408
3293
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.5
6.5
357
2814
E000002, ,
ATC
1.8
6.3
91
522
B08.4
ICD-10 Finland
Enteroviral vesicular stomatitis with exanthem
8.2
6.3
13
16
J01EA01
ATC
trimethoprim; systemic
1.5
6.3
214
1532
D07XC01
ATC
betamethasone; topical
1.8
6.3
92
531
5280A
ICD-9 Finland
Diseases of the oral soft tissues, excluding lesions specific for gingiva and tongue, Stomatitis
+∞
6.3
6
*
134
Kela drug reimbursment
General erythroderma
+∞
6.3
6
*
L29.9
ICD-10 Finland
Pruritus, unspecified
2.8
6.2
29
104
N03AX12
ATC
[U] gabapentin; oral
1.7
6.2
133
855
KA1AE
NOMESCO Finland
Kidney ultrasound examination
3.2
6.2
24
77
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.5
6.2
226
1643
SPAT1156
SPAT
Guidance concerning treatment of rash and skin
1.7
6.2
107
649
L40.5
ICD-10 Finland
Arthropathic psoriasis
4.0
6.2
17
43
N06AX11
ATC
mirtazapine; oral
1.5
6.2
276
2089
TDM10
NOMESCO Finland
Puncture of maxillary antrum
2.5
6.2
36
145
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
1.6
6.1
159
1072
T82
ICPC
Obesity
2.5
6.1
38
158
W19
ICD-10 Finland
Unspecified fall
1.8
6.1
85
484
N03AG01
ATC
valproic acid; systemic, rectal
2.1
6.1
55
269
K12.00
ICD-10 Finland
Recurrent oral aphthae
3.6
6.1
19
53
D06
ICPC
Abdominal pain localized other
1.9
6.0
70
375
L98.9
ICD-10 Finland
Disorder of skin and subcutaneous tissue, unspecified
3.9
6.0
17
44
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
50
40
13.19
51.59
1.7
1.4
31.08
20.00
u/ml
—
13
5
96
210
5.01
41.85
2.6
1.4
0.21
0.23
g/l
1.67
90
201
97
217
4.90
41.16
2.6
1.4
1.12
1.19
g/l
1.12
91
204
36
42
8.89
28.56
1.2
1.2
—
—
—
0
0
43
65
6.90
27.42
1.4
1.3
—
—
—
0
0
575
4064
2.18
26.39
14.1
9.0
4.13
4.11
e9/l
0.05
521
3571
493
3310
2.10
25.55
11.2
5.8
2.93
2.85
%
0.23
469
3090
75
206
3.89
24.19
2.6
1.8
—
—
—
0
0
500
3421
2.06
24.07
11.3
5.9
26.98
28.15
%
1.53
476
3210
495
3381
2.05
23.87
11.0
5.7
57.52
57.15
%
0.28
473
3176
55
124
4.66
22.96
8.4
7.0
962.87
397.27
iu/ml
—
8
15
56
135
4.36
21.50
1.7
1.2
1.67
8.65
u/ml
—
6
10
55
137
4.21
20.23
1.5
1.1
—
—
—
0
0
63
175
3.80
19.97
1.8
1.2
4.33
11.63
u/ml
0.60
15
30
62
174
3.76
19.36
1.8
1.2
2.81
2.65
u/ml
—
10
20
65
189
3.63
19.28
1.8
1.2
50.23
2.28
u/ml
—
6
9
425
2895
1.90
19.14
6.9
4.7
35.17
35.75
g/l
1.28
395
2693
64
187
3.61
18.84
1.3
1.3
—
—
—
0
0
113
464
2.65
18.51
2.1
1.6
—
—
—
0
0
673
5374
2.05
18.34
11.2
7.3
76.67
78.11
u/l
0.46
637
5040
53
139
3.99
18.20
1.2
1.2
—
—
—
0
0
203
1093
2.11
17.82
2.4
1.8
—
—
—
0
0
62
186
3.51
17.54
1.1
1.1
—
—
—
0
0
470
3370
1.84
17.42
9.0
6.7
1.21
1.22
mmol/l
0.74
417
2852
26
39
6.84
16.65
2.0
2.5
—
—
—
0
0
27
43
6.45
16.36
2.1
2.4
484.90
567.19
e6/l
0.27
20
36
430
3052
1.80
16.01
7.6
6.1
1.20
1.21
mmol/l
2.12
408
2767
119
536
2.41
15.97
3.8
2.9
11.34
10.52
g/l
0.83
106
492
26
42
6.35
15.54
2.1
2.5
0.18
0.19
e9/l
0.08
20
36
487
3610
1.78
15.42
8.2
6.1
11.67
11.16
umol/l
0.31
459
3416
66
226
3.08
15.09
2.4
1.5
93.33
111.43
titre
—
6
7
47
134
3.65
14.35
1.3
1.2
300.36
264.56
u/ml
0.26
32
80
44
120
3.81
14.32
1.4
1.3
110.17
103.45
u/ml
—
9
22
635
5181
1.80
13.54
6.7
4.0
14.21
11.69
mm/h
3.48
607
4799
48
152
3.28
12.50
1.7
1.2
39.33
28.68
u/ml
—
6
13
142
759
2.04
12.38
2.4
1.7
—
—
—
0
0
49
161
3.16
12.02
2.6
1.6
—
—
—
0
0
39
113
3.56
11.65
2.1
1.6
—
—
—
0
0
108
532
2.17
11.64
2.8
2.9
65.45
66.74
g/l
0.86
102
484
141
769
1.99
11.58
2.5
1.8
—
—
—
0
0
64
253
2.65
11.25
2.6
2.0
1.35
2.67
ug/l
0.47
57
223
48
163
3.06
11.15
2.5
1.6
—
—
—
0
0
311
2174
1.66
11.10
3.0
2.4
52.44
61.65
u/l
2.19
286
2017
39
117
3.44
11.06
2.7
1.7
—
—
—
0
0
21
41
5.22
10.35
1.6
1.2
—
—
—
0
0
31
85
3.74
10.05
1.4
1.6
—
—
—
0
0
37
115
3.31
9.95
2.8
1.6
—
—
—
0
0
37
115
3.31
9.95
2.8
1.6
—
—
—
0
0
290
2037
1.63
9.93
2.7
2.1
178.18
255.66
u/l
0.67
277
1928
158
953
1.80
9.43
2.6
2.4
2.29
2.35
g/l
0.75
145
886
33
99
3.42
9.38
1.4
1.5
—
—
—
0
0
566
4684
1.58
9.36
6.1
4.3
20.83
1957.48
e6/l
—
6
69
21
29
7.39
9.25
1.0
1.0
—
—
—
0
0
234
1581
1.65
9.25
1.8
1.7
0.99
1.08
mg/l
0.34
177
1198
56
235
2.48
8.74
1.8
2.3
—
—
—
0
0
145
873
1.79
8.67
2.7
2.4
134.27
119.71
ug/g
0.24
119
686
215
1444
1.65
8.63
1.9
1.4
2.41
2.37
g/l
0.10
152
893
438
3473
1.52
8.42
4.9
3.6
0.00
0.00
estimate
0.50
80
722
147
898
1.76
8.35
8.5
5.8
1.06
1.05
mmol/l
0.29
136
827
188
1234
1.66
8.21
1.3
1.3
39.77
33.18
iu/ml
0.25
65
401
437
3478
1.51
8.16
6.5
4.8
0.00
0.00
estimate
0.50
76
688
53
224
2.45
8.16
1.5
1.5
0.01
0.09
iu/ml
0.90
12
44
27
78
3.54
8.14
2.6
1.7
—
—
—
0
0
25
69
3.70
8.05
2.6
1.8
—
—
—
0
0
494
4044
1.50
7.98
6.3
4.8
6.56
6.64
mmol/l
0.37
465
3763
78
394
2.07
7.86
1.7
1.5
—
—
—
0
0
325
2448
1.52
7.81
5.1
3.2
—
—
—
0
0
209
1425
1.61
7.81
1.7
1.6
—
—
—
0
0
164
1054
1.68
7.73
2.8
2.4
12.95
13.05
umol/l
0.06
154
986
393
3089
1.49
7.64
16.9
13.3
1.22
1.22
inr
0.01
111
906
108
619
1.85
7.55
2.9
2.2
0.21
0.21
g/l
0.07
95
581
144
899
1.72
7.54
2.8
2.5
23.80
22.77
%
0.28
122
778
438
3525
1.48
7.52
5.0
3.6
0.00
0.00
estimate
0.50
77
664
175
1157
1.64
7.37
1.3
1.3
15.67
11.62
u/ml
0.24
62
447
49
210
2.41
7.34
2.1
2.6
0.86
1.15
g/l
0.22
44
186
353
2733
1.49
7.30
2.1
1.9
95.36
95.33
pmol/l
0.00
178
1397
28
90
3.18
7.19
1.5
1.2
—
—
—
0
0
79
415
1.99
7.17
8.5
7.9
25.36
24.60
mmol/l
0.95
72
397
26
80
3.32
7.15
2.5
1.5
—
—
—
0
0
26
80
3.32
7.15
2.5
1.5
—
—
—
0
0
106
618
1.81
7.01
7.8
8.6
120.40
121.07
g/l
0.11
99
605
22
63
3.56
6.75
2.3
1.7
—
—
—
0
0
22
63
3.56
6.75
2.3
1.7
—
—
—
0
0
22
63
3.56
6.75
2.3
1.7
—
—
—
0
0
19
49
3.94
6.73
4.6
2.7
47.10
42.00
%
—
10
26
123
759
1.72
6.70
7.1
7.8
1.91
1.26
mmol/l
1.22
97
607
176
1194
1.59
6.62
1.8
1.7
1216.90
1186.84
nmol/l
0.14
135
884
43
183
2.42
6.56
1.4
1.2
—
—
—
0
0
26
85
3.12
6.51
2.3
1.6
—
—
—
0
0
106
632
1.77
6.51
4.4
4.2
6.01
5.85
kpa
0.90
101
614
238
1739
1.50
6.38
3.6
2.6
2175.79
5755.94
umol/l
1.02
203
1523
108
651
1.75
6.38
2.2
2.0
304.82
369.70
nmol/l
2.83
100
601
49
224
2.26
6.37
1.3
1.3
—
—
—
0
0
36
143
2.58
6.34
1.7
1.6
—
—
—
0
0
97
570
1.79
6.25
11.4
7.6
9.67
9.27
mmol/l
0.21
92
542
104
625
1.75
6.21
4.4
4.2
2.51
1.90
mmol/l
1.00
90
518
117
728
1.70
6.17
4.5
2.6
1.83
1.79
%
0.11
108
649
12
14
8.67
6.07
1.3
1.1
—
—
—
0
0
393
3189
1.42
5.99
3.3
2.7
135.39
113.70
ug/l
0.69
368
2948
121
766
1.67
5.98
7.2
7.8
12.16
12.32
kpa
0.12
111
736
121
766
1.67
5.98
7.2
7.8
5.07
5.13
kpa
0.33
112
732
218
1598
1.48
5.68
1.7
1.5
20.66
20.91
nmol/l
0.08
196
1361
247
1860
1.45
5.59
3.4
2.9
1474.27
1245.41
ng/l
0.31
213
1558
235
1755
1.46
5.55
2.3
2.1
2.98
3.07
mg/l
0.23
201
1482
20
62
3.28
5.47
1.2
1.1
—
—
—
0
0
20
62
3.28
5.47
1.2
1.1
—
—
—
0
0
150
1027
1.55
5.37
2.6
2.1
28.86
29.54
s
0.91
143
996
772
7158
1.61
5.35
23.5
13.4
22.67
23.66
mg/l
0.39
649
5630
20
63
3.22
5.34
1.2
1.1
—
—
—
0
0
20
63
3.22
5.34
1.2
1.1
—
—
—
0
0
20
63
3.22
5.34
1.2
1.1
—
—
—
0
0
18
53
3.45
5.33
1.6
1.3
248698.80
208959.79
e6/l
—
10
33
621
5516
1.42
5.32
4.4
3.9
14.72
14.70
pmol/l
0.06
577
5002
52
264
2.03
5.23
2.2
1.9
—
—
—
0
0
355
2880
1.39
5.21
2.8
2.3
75.87
76.93
nmol/l
0.31
321
2570
549
4803
1.38
4.95
4.4
3.0
48.91
45.40
u/l
0.60
521
4496
548
4793
1.38
4.94
3.5
3.1
—
—
—
0
0
295
2340
1.39
4.89
5.4
3.3
37.76
31.30
u/l
0.35
279
2237
44
216
2.09
4.85
3.2
3.0
—
—
—
0
0
323
2607
1.38
4.80
4.8
3.5
23.68
51.53
ng/l
1.22
225
1734
35
158
2.27
4.74
1.9
1.6
—
—
—
0
0
20
68
2.99
4.74
1.6
1.2
—
—
—
0
0
25
97
2.62
4.67
2.1
1.6
—
—
—
0
0
158
1126
1.49
4.67
4.0
2.7
0.94
1.08
e6/l
0.32
97
640
19
64
3.01
4.57
2.2
2.4
—
—
—
0
0
153
1090
1.49
4.52
5.3
3.5
0.82
0.82
mmol/l
0.09
143
1019
193
1440
1.44
4.49
4.0
2.6
5.16
6.24
e6/l
0.44
182
1289
81
498
1.69
4.48
2.6
3.0
164.86
188.33
ng/l
0.25
70
451
41
203
2.07
4.44
2.5
3.0
3.84
3.56
g/l
0.55
35
194
331
2715
1.35
4.34
5.3
3.7
—
—
—
0
0
267
2118
1.37
4.33
3.7
3.2
7.27
7.57
mmol/l
0.55
231
1791
85
535
1.65
4.31
2.9
2.5
6.70
7.09
ug/l
0.08
77
474
18
61
2.99
4.30
1.3
1.0
—
—
—
0
0
13
29
4.53
4.25
1.2
1.1
401.46
120.47
iu/ml
1.23
13
29
33
155
2.17
4.10
2.0
1.6
20359.93
17725.84
e6/l
0.08
27
112
22
86
2.60
4.07
1.2
1.2
—
—
—
0
0
239
1879
1.37
4.07
4.9
3.1
0.40
0.45
e6/l
0.10
192
1421
30
138
2.22
3.93
1.5
1.3
—
—
—
0
0
30
138
2.22
3.93
1.5
1.3
—
—
—
0
0
286
2323
1.34
3.92
3.8
3.3
2.35
2.35
mmol/l
0.47
255
2051
36
179
2.05
3.89
1.5
1.3
—
—
—
0
0
238
1889
1.36
3.78
5.6
3.9
0.00
0.01
estimate
0.88
74
672
26
115
2.30
3.74
1.1
1.1
—
—
—
0
0
19
73
2.64
3.66
2.9
1.6
—
—
—
0
0
16
56
2.89
3.64
1.1
1.0
—
—
—
0
0
38
198
1.96
3.63
3.5
3.9
32.22
42.82
mg/l
0.30
30
161
38
198
1.96
3.63
3.5
3.9
38.70
81.47
mg/l
0.72
30
161
48
271
1.82
3.60
7.0
6.8
1.98
1.56
%
1.63
43
256
7
9
7.83
3.56
1.0
1.2
—
—
—
0
0
112
790
1.48
3.48
4.9
2.9
9.02
8.25
umol/l
0.12
100
682
144
1068
1.42
3.43
4.2
3.0
2.55
2.61
e6/l
0.02
80
585
11
27
4.11
3.40
3.5
1.9
—
—
—
0
0
11
27
4.11
3.40
3.5
1.9
—
—
—
0
0
63
392
1.65
3.38
2.0
1.6
—
—
—
0
0
35
183
1.95
3.33
1.3
1.5
330.56
301.38
ug/g
0.39
20
106
11
28
3.96
3.29
3.5
1.9
—
—
—
0
0
113
808
1.46
3.28
10.1
6.8
—
—
—
0
0
253
2064
1.32
3.28
5.1
3.2
19.20
90.16
e6/l
1.47
208
1583
20
84
2.41
3.24
1.6
1.5
73.17
60.92
%
0.93
12
63
196
1544
1.35
3.23
6.3
3.9
1.02
1.02
kg/l
0.65
26
208
37
200
1.89
3.20
1.9
1.5
—
—
—
0
0
8
15
5.37
3.19
1.1
1.1
87.75
100.13
%
—
8
15
162
1241
1.37
3.18
3.1
2.9
2.45
2.44
mmol/l
0.58
145
1082
43
245
1.79
3.16
1.2
1.3
182.69
264.75
miu/ml
0.50
13
121
25
118
2.15
3.12
1.1
1.2
—
—
—
0
0
12
35
3.46
3.11
3.3
1.8
—
—
—
0
0
12
35
3.46
3.11
1.8
1.2
—
—
—
0
0
12
35
3.46
3.11
3.3
1.8
—
—
—
0
0
12
35
3.46
3.11
1.8
1.2
—
—
—
0
0
29
147
2.01
3.03
9.1
10.4
104.46
105.44
mmol/l
0.49
24
134
246
2021
1.30
2.99
4.0
3.8
19.03
9.72
mg/mmol
0.87
151
1261
78
527
1.53
2.99
3.2
2.6
61.94
67.06
ml/min/173m2
0.48
34
220
29
149
1.98
2.92
2.7
1.4
—
—
—
0
0
42
244
1.76
2.92
1.7
1.7
—
—
—
0
0
234
1917
1.30
2.90
3.7
3.2
1186.36
194.57
mg/l
1.09
147
1229
703
6589
1.33
2.89
5.3
4.6
1.92
2.06
mu/l
0.33
663
6034
13
47
2.79
2.82
1.2
1.1
—
—
—
0
0
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
34
188
1.84
2.78
3.0
2.9
0.33
0.34
u/ml
0.05
20
107
206
1668
1.31
2.78
1.4
1.3
1.59
1.53
u/ml
0.03
56
449
60
390
1.58
2.74
1.5
1.3
—
—
—
0
0
212
1726
1.30
2.74
5.9
3.8
89.02
92.23
%
1.23
204
1681
7
14
5.03
2.73
1.0
1.0
—
—
—
0
0
7
14
5.03
2.73
1.0
2.1
—
—
—
0
0
40
234
1.74
2.73
2.0
1.6
—
—
—
0
0
98
709
1.43
2.69
4.7
3.2
—
—
—
0
0
176
1400
1.32
2.69
1.7
1.7
48322582.81
30375862.80
pmol/l
0.14
149
1172
14
55
2.57
2.62
2.0
2.5
—
—
—
0
0
765
7288
1.37
2.60
24.0
15.3
3.95
3.96
mmol/l
0.64
751
7080
7
15
4.69
2.60
2.0
2.5
—
—
—
0
0
158
1245
1.33
2.58
4.0
3.7
170.85
342.15
ng/l
0.74
126
927
763
7268
1.36
2.58
23.9
15.2
139.27
139.68
mmol/l
4.24
751
7070
6
11
5.48
2.54
1.0
4.6
—
—
—
0
0
12
45
2.69
2.46
1.1
1.1
64.83
73.93
u/l
0.23
12
40
18
83
2.19
2.42
2.4
1.4
—
—
—
0
0
7
17
4.14
2.36
1.3
1.1
—
—
—
0
0
671
6305
1.27
2.35
25.3
15.9
14.72
14.85
%
0.28
664
6201
11
39
2.84
2.35
1.5
1.5
—
—
—
0
0
17
78
2.20
2.32
1.1
1.1
51.53
52.07
u/l
0.03
17
73
14
59
2.39
2.30
3.9
1.6
—
—
—
0
0
18
85
2.14
2.30
2.4
1.4
—
—
—
0
0
18
85
2.14
2.30
2.4
1.4
—
—
—
0
0
10
34
2.96
2.28
5.9
3.0
—
—
—
0
0
24
127
1.91
2.28
4.0
2.4
15.15
15.87
%
0.31
13
63
25
135
1.88
2.24
3.5
3.8
4.00
4.25
e9/l
0.25
25
135
5
9
5.58
2.21
5.2
1.8
—
—
—
0
0
13
54
2.43
2.20
1.6
1.6
—
—
—
0
0
6
14
4.31
2.15
1.3
1.4
—
—
—
0
0
18
88
2.07
2.12
1.1
1.0
1.49
1.47
g/l
0.06
18
80
39
246
1.61
2.07
1.5
1.4
—
—
—
0
0
73
527
1.42
2.07
4.8
4.0
90.13
81.94
ng/l
0.42
66
473
7
20
3.52
2.06
2.6
2.2
—
—
—
0
0
28
162
1.75
2.04
1.6
1.4
2.10
10.40
e6/l
1.17
21
127
25
141
1.80
1.98
3.6
4.0
55.88
56.96
%
0.16
25
141
61
431
1.45
1.95
2.9
3.2
4.49
4.55
pmol/l
0.15
53
380
60
423
1.45
1.94
5.3
3.9
2.62
1.89
mmol/l
0.98
46
315
9
34
2.66
1.87
1.2
1.5
—
—
—
0
0
67
487
1.41
1.85
2.8
2.2
11.61
12.71
nmol/l
0.49
60
442
33
206
1.63
1.85
1.3
1.1
—
—
—
0
0
20
108
1.87
1.83
1.5
1.4
0.82
0.31
nmol/l
0.41
15
86
85
646
1.35
1.80
2.8
2.3
33.51
34.27
u/l
0.06
74
546
9
35
2.59
1.80
1.2
1.5
—
—
—
0
0
7
23
3.06
1.80
1.3
1.0
—
—
—
0
0
33
208
1.61
1.79
1.3
1.1
—
—
—
0
0
12
54
2.24
1.74
1.3
1.1
0.31
0.89
u/ml
—
7
25
787
7612
1.31
1.73
16.5
9.9
27.10
25.72
u/l
0.87
767
7348
13
61
2.15
1.72
1.4
1.3
6.47
6.46
mmol/l
0.01
13
55
5
13
3.86
1.71
1.4
1.3
—
—
—
0
0
13
62
2.11
1.66
1.8
1.4
—
—
—
0
0
84
1073
0.76
1.62
3.2
3.0
0.81
0.79
ug/l
0.04
68
694
366
3314
1.18
1.61
3.2
2.5
—
—
—
0
0
16
84
1.92
1.60
2.6
1.4
—
—
—
0
0
11
50
2.22
1.57
1.5
1.6
—
—
—
0
0
69
524
1.34
1.50
2.3
2.0
—
—
—
0
0
674
6449
1.19
1.41
5.9
5.4
38.88
39.47
mmol/mol
1.00
628
5991
5
18
2.79
1.28
1.2
1.0
—
—
—
0
0
33
227
1.47
1.28
2.2
2.6
97.00
92.39
%
0.54
33
215
15
84
1.80
1.27
2.7
1.4
—
—
—
0
0
23
146
1.59
1.27
3.0
2.1
122.12
129.92
g/l
0.70
17
107
23
146
1.59
1.27
2.2
1.4
—
—
—
0
0
15
85
1.78
1.23
2.7
1.4
—
—
—
0
0
190
1668
1.18
1.19
2.8
2.2
—
—
—
0
0
112
939
1.22
1.16
2.5
2.1
—
—
—
0
0
54
414
1.32
1.15
2.3
1.9
—
—
—
0
0
211
1878
1.16
1.11
1.8
1.7
1.27
1.38
mmol/l
1.43
181
1589
108
906
1.22
1.11
2.0
1.8
1.42
1.44
%
0.06
90
808
102
851
1.22
1.11
2.3
2.0
—
—
—
0
0
5
21
2.39
1.09
1.4
1.2
8.56
8.70
ug/l
—
5
21
8
41
1.96
1.09
1.0
1.2
—
—
—
0
0
7
32
2.20
1.08
2.1
1.2
—
—
—
0
0
7
32
2.20
1.08
2.1
1.2
—
—
—
0
0
39
289
1.37
1.05
1.9
2.2
7852.20
4643.24
u/l
0.18
13
128
5
22
2.28
1.03
1.0
1.0
—
—
—
0
0
10
53
1.90
1.01
2.2
1.6
0.80
1.01
g/l
—
10
53
10
53
1.90
1.01
1.0
1.2
—
—
—
0
0
12
68
1.78
1.01
2.1
2.5
—
—
—
0
0
10
54
1.86
0.97
1.2
1.2
—
—
—
0
0
10
54
1.86
0.97
1.2
1.2
—
—
—
0
0
21
141
1.50
0.95
1.5
1.9
4.74
4.97
mmol/24h
0.11
16
123
7
37
1.90
0.94
1.6
1.4
—
—
—
0
0
7
37
1.90
0.94
1.6
1.4
—
—
—
0
0
6
27
2.23
0.93
2.0
1.9
32.00
76.03
ug/l
—
6
27
6
28
2.15
0.91
4.3
1.5
—
—
—
0
0
6
28
2.15
0.91
1.3
1.3
—
—
—
0
0
41
315
1.32
0.90
1.3
1.4
25.78
26.85
iu/l
0.07
36
269
6
29
2.08
0.89
1.2
1.1
1453.17
1657.79
miu/ml
—
6
29
142
1255
1.16
0.84
1.6
1.4
—
—
—
0
0
45
355
1.28
0.83
8.2
9.1
24.98
24.56
mmol/l
0.51
45
345
15
97
1.56
0.81
1.3
1.3
—
—
—
0
0
8
47
1.71
0.81
1.3
1.3
—
—
—
0
0
17
114
1.50
0.80
3.7
3.2
0.83
0.88
nmol/l
0.18
11
89
5
24
2.09
0.74
1.4
1.8
28.60
31.21
umol/l
—
5
24
7
38
1.85
0.73
1.3
1.1
—
—
—
0
0
5
27
1.86
0.68
1.4
1.6
—
—
—
0
0
7
44
1.60
0.65
1.0
1.5
1.80
1.52
g/l
—
7
44
18
129
1.40
0.63
1.2
1.1
0.36
4.47
u/ml
2.31
11
70
58
684
0.84
0.63
1.7
1.6
—
—
—
0
0
5
30
1.67
0.61
1.6
1.4
—
—
—
0
0
16
113
1.42
0.61
1.2
1.1
—
—
—
0
0
813
8023
1.16
0.58
32.4
19.5
39.40
40.21
%
3.43
754
7535
11
73
1.51
0.56
3.7
3.3
—
—
—
0
0
17
124
1.38
0.56
1.7
4.0
53.88
2284.57
u/ml
0.61
17
119
813
8028
1.16
0.55
32.3
19.5
250.51
252.14
e9/l
0.29
803
7824
(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
6
39
1.54
0.53
1.2
1.2
—
—
—
0
0
813
8031
1.15
0.52
32.3
19.5
4.40
4.50
e12/l
6.68
800
7814
23
181
1.28
0.48
1.3
1.2
—
—
—
0
0
7
46
1.53
0.48
1.6
1.7
—
—
—
0
0
136
1475
0.91
0.46
4.7
4.2
20.97
21.34
%
0.09
69
679
12
86
1.40
0.44
5.1
2.1
34.00
32.83
pg
0.56
12
86
18
139
1.30
0.44
1.7
1.7
—
—
—
0
0
5
31
1.62
0.43
1.2
1.0
—
—
—
0
0
0
15
0.00
0.41
0.0
1.1
—
—
—
0
0
23
186
1.24
0.40
1.3
1.4
265.61
203.40
pmol/l
0.17
23
181
12
88
1.37
0.40
3.1
2.6
106.33
105.45
mmol/l
0.13
12
88
12
88
1.37
0.40
3.1
2.6
3.82
4.05
mmol/l
1.22
12
88
5
35
1.43
0.39
1.6
1.7
—
—
—
0
0
14
106
1.33
0.39
1.3
1.2
3.29
6.13
u/ml
—
7
45
6
43
1.40
0.35
1.5
1.4
—
—
—
0
0
6
44
1.37
0.34
2.5
1.4
—
—
—
0
0
34
388
0.87
0.30
1.5
1.5
—
—
—
0
0
176
1850
0.94
0.30
5.6
4.8
2.76
2.41
ug/l
0.16
159
1655
14
174
0.80
0.30
1.4
1.7
—
—
—
0
0
22
185
1.19
0.29
1.4
1.9
3.90
5.36
iu/l
—
6
66
14
112
1.25
0.28
1.1
1.2
2.57
4.47
u/ml
—
7
34
12
94
1.28
0.28
1.3
1.1
—
—
—
0
0
19
225
0.84
0.26
1.4
1.5
—
—
—
0
0
9
76
1.19
0.24
1.0
1.1
—
—
—
0
0
5
38
1.32
0.23
1.2
1.1
76.60
105.41
u/l
—
5
38
5
38
1.32
0.23
1.2
1.1
8.00
34.55
u/l
—
5
38
720
7129
1.05
0.23
5.1
4.7
2.74
2.79
mmol/l
0.76
667
6599
13
107
1.22
0.21
1.7
1.6
—
—
—
0
0
5
42
1.19
0.21
1.0
1.3
174.34
177.15
pmol/l
—
5
42
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
12
0.00
0.21
0.0
2.8
—
0.67
—
0
12
0
12
0.00
0.21
0.0
1.3
—
—
—
0
0
678
6710
1.04
0.20
17.9
12.1
83.73
82.99
ml/min/173m2
0.34
553
5516
10
81
1.24
0.19
1.3
1.0
—
—
—
0
0
692
6858
1.04
0.18
5.3
4.3
5.88
5.89
mmol/l
0.08
642
6264
29
263
1.11
0.16
1.7
1.5
—
—
—
0
0
8
68
1.18
0.16
1.0
1.1
—
—
—
0
0
6
78
0.77
0.15
1.0
1.1
99.33
94.63
%
—
6
72
22
197
1.12
0.15
2.3
1.7
38.18
39.38
nmol/l
0.10
22
186
73
693
1.06
0.15
3.1
4.2
12.79
30.38
ug/l
0.57
60
572
26
286
0.91
0.15
1.8
1.9
—
—
—
0
0
9
80
1.13
0.15
1.0
1.1
—
—
—
0
0
19
210
0.90
0.12
1.5
1.4
—
—
—
0
0
19
210
0.90
0.12
1.5
1.4
—
—
—
0
0
19
209
0.91
0.11
1.5
1.4
—
—
—
0
0
19
209
0.91
0.11
1.5
1.4
—
—
—
0
0
5
45
1.11
0.10
1.6
1.4
—
—
—
0
0
22
203
1.09
0.09
2.5
1.7
—
—
—
0
0
13
144
0.90
0.08
1.3
1.5
—
—
—
0
0
12
108
1.11
0.07
1.0
1.1
—
—
—
0
0
21
196
1.07
0.07
1.2
1.6
—
—
—
0
0
88
865
1.02
0.04
4.4
4.3
34.03
32.17
%
0.74
63
598
672
6738
0.99
0.03
4.2
3.8
1.29
1.28
mmol/l
0.05
624
6208
29
300
0.97
0.03
2.6
1.8
3.82
3.08
mg/l
0.28
24
220
51
521
0.98
0.03
1.2
1.2
56.64
154.12
iu/ml
2.99
22
217
702
7009
1.01
0.02
4.7
4.2
4.64
4.70
mmol/l
0.79
656
6519
699
6979
1.01
0.02
4.6
4.2
1.48
1.48
mmol/l
0.00
652
6467
38
373
1.02
0.01
1.1
1.0
—
—
—
0
0
26
258
1.01
0.00
1.5
1.4
—
—
—
0
0
0
7
0.00
0.00
0.0
1.4
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
65.67
—
0
6
5
53
0.94
-0.00
1.0
1.0
—
—
—
0
0
25
250
1.00
-0.00
1.6
1.5
261.50
312.98
mu/l
0.69
20
231
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
8
0.00
-0.00
0.0
2.6
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
16.80
—
0
5
0
9
0.00
-0.00
0.0
2.4
—
—
—
0
0
5
57
0.88
-0.00
1.2
1.1
253.20
228.79
mg/l
—
5
48
Mortality – FinRegistry
↥Association
Association between endpoint L12_ERYTHEMAMULTIF and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| L12_ERYTHEMAMULTIF | 1.578 [1.37, 1.82] | < 0.001 |
| Birth year | 0.992 [0.98, 1.0] | 0.068 |
During the follow-up period (1.1.1998 — 31.12.2019), 521 out of 2889 females with L12_ERYTHEMAMULTIF died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| L12_ERYTHEMAMULTIF | 1.557 [1.32, 1.83] | < 0.001 |
| Birth year | 0.982 [0.97, 0.99] | < 0.001 |
During the follow-up period (1.1.1998 — 31.12.2019), 415 out of 2388 males with L12_ERYTHEMAMULTIF died.
Mortality risk
Mortality risk for people of age
years, who have L12_ERYTHEMAMULTIF.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.167% | 0.238% |
| 5 | 0.852% | 1.464% |
| 10 | 2.022% | 3.826% |
| 15 | 3.886% | 7.226% |
| 20 | 6.825% | 12.223% |
Relationships between endpoints
↥Index endpoint: L12_ERYTHEMAMULTIF – Erythema multiforme
GWS hits: 1
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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