Other hypertrichosis

L12_HYPERTICHNAS

No definition available.

Endpoint definition

↥

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps	FinnGen
Phenotype data	519972
1. Apply sex-specific rule None	519972
2. Check conditions None	519972
3. Check pre-conditions, main-only, mode, registry filters Registry filters: Hospital discharge: ICD-10 — L68.8, L68.9 Hospital discharge: ICD-9 — 7041C Hospital discharge: ICD-8 — 70405 Cause of death: ICD-10 — L68.8, L68.9 Cause of death: ICD-9 — 7041C Cause of death: ICD-8 — 70405 2 out of 7 registries used, show all original rules.	127
4. Check minimum number of events None	127
5. Include endpoints None	127
6. Filter based on genotype QC (FinnGen only)	117

Control definitions (FinnGen only)

Control exclude: L12_DISORDSKINAPPENDIX

Extra metadata

Level in the ICD hierarchy: 4
First used in FinnGen datafreeze: DF2

NAME	L12_HYPERTICHNAS
CONTROL_EXCLUDE	L12_DISORDSKINAPPENDIX
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX
INCLUDE
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10	L68[8-9]
HD_ICD_9	7041C
HD_ICD_8	70405
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10	L68[8-9]
COD_ICD_9	7041C
COD_ICD_8	70405
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

Similar endpoints

↥

List of similar endpoints to Other hypertrichosis based on the number of shared cases.

Similar with more cases:

Similar with less cases:

None

Case counts by codes

↥

FinnGen case counts by registry codes:

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

Key figures

	All	Female	Male
Number of individuals
Whole population	887	839	42
Only index persons	815	776	39
Unadjusted period prevalence (%)
Whole population	0.02	0.02	0.00
Only index persons	0.03	0.03	0.00
Median age at first event (years)
Whole population	27.97	28.09	25.14
Only index persons	28.02	28.20	24.35

-FinnGen-

Key figures

	All	Female	Male
Number of individuals	117	111	6
Unadjusted period prevalence (%)	0.04	0.04	0.00
Median age at first event (years)	30.44	30.33	32.52

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log₁₀(p-value) ≥ 6.

Matched cohort

Matched cases
127: Matched controls
1270

Code

Vocabulary

Description

Odds Ratio

-log₁₀(p)

N matched cases

N matched controls

L68.9

ICD-10 Finland

Hypertrichosis, unspecified

+∞

82.5

L68.0

ICD-10 Finland

Hirsutism

+∞

45.6

70405

ICD-8 Finland

Diseases of hair and hair follicles, Hypertrichosis

+∞

36.2

L68.8

ICD-10 Finland

Other hypertrichosis

+∞

29.3

C03DA01

ATC

spironolactone; oral

8.6

21.0

G03HB01

ATC

cyproterone and estrogen; oral

4.0

11.1

136

E28.2

ICD-10 Finland

Polycystic ovarian syndrome

13.8

10.7

A10BA02

ATC

metformin; oral

3.3

8.3

149

E66.8

ICD-10 Finland

Other obesity

7.5

8.3

E66.01

ICD-10 Finland

Obesity due to excess calories

3.5

7.0

G47.3

ICD-10 Finland

Sleep apnoea

3.1

6.1

116

LabWAS

↥

N Cases

N Controls

-log₁₀(p)

cases

controls

cases

controls

unit

-log₁₀(p)

N cases

N controls

(3009214) Lutropin [Units/volume] in Serum or Plasma

7.74

16.04

1.6

1.3

9.90

8.73

u/l

0.19

(3021387) Prolactin [Units/volume] in Serum or Plasma

5.89

14.69

1.6

1.4

266.52

261.95

mu/l

0.05

(3004248) Sex hormone binding globulin [Moles/volume] in Serum or Plasma

27.73

12.85

1.4

1.3

41.59

29.86

nmol/l

—

(3023530) 17-Hydroxyprogesterone [Moles/volume] in Serum or Plasma

+∞

7.36

1.6

0.0

2.11

—

nmol/l

—

(3020911) Cortisol [Moles/time] in 24 hour Urine

10.65

5.11

1.8

1.6

82.00

58.22

nmol/24h

—

(40763571) Iron/Transferrin [Ratio] in Serum or Plasma

2.93

4.91

4.2

2.3

25.07

23.03

0.18

(3035637) Corticotropin [Mass/volume] in Plasma

8.70

4.64

3.0

1.6

—

(3029287) Urinalysis microscopic panel [#/volume] - Urine by Automated count

321

2.19

4.34

4.1

2.9

—

(3030467) Casts [#/volume] in Urine by Automated count

258

2.23

4.25

4.4

2.7

0.19

0.35

e6/l

0.46

184

(36304419) Bacteria [Presence] in Urine

263

2.17

4.02

4.3

2.6

—

(3015377) Calcium [Moles/volume] in Serum or Plasma

307

2.04

3.56

2.9

2.6

2.37

2.35

mmol/l

0.50

278

(3002582) Erythrocytes [#/volume] in Urine

286

2.02

3.41

4.5

3.0

12.95

71.36

e6/l

1.59

211

(3030306) Epithelial cells.non-squamous [#/volume] in Urine by Automated count

154

2.24

3.36

3.4

2.3

0.82

0.83

e6/l

0.02

(43054903) Holo-transcobalamin II [Moles/volume] in Serum

374

1.95

3.32

2.1

1.8

102.60

95.35

pmol/l

0.63

186

(3018095) Leukocytes [#/volume] in Urine

358

1.95

3.26

5.6

3.7

31.02

65.57

e6/l

0.60

227

(44816844) Macroprolactin [Units/volume] in Serum or Plasma

4.76

3.18

1.7

1.2

—

(3018418) pH of Serum or Plasma

276

1.98

3.15

4.7

4.1

7.40

—

(3003458) Phosphate [Moles/volume] in Serum or Plasma

2.40

2.97

7.1

5.5

1.01

1.06

mmol/l

0.33

(3051714) Fibrin D-dimer FEU [Mass/volume] in Platelet poor plasma

226

1.97

2.88

1.9

0.76

0.70

mg/l

0.08

173

(40761535) Cells panel - Urine sediment

2.70

2.82

2.7

3.1

—

(3029879) Epithelial cells.squamous [#/volume] in Urine by Automated count

151

2.10

2.75

3.5

2.5

2.94

3.84

e6/l

0.28

(40758558) Short blood count panel - Blood

271

1.89

2.73

4.6

6.3

—

(3009261) Glucose [Presence] in Urine by Test strip

523

1.81

2.72

4.6

3.2

0.00

estimate

-0.00

106

(3021601) Nitrite [Presence] in Urine by Test strip

514

1.81

2.71

5.9

4.4

0.00

estimate

-0.00

110

(3002256) Pathology report gross observation

109

2.23

2.66

1.1

—

(3011397) Hemoglobin [Presence] in Urine by Test strip

224

1.92

2.64

4.8

3.1

—

(3035350) Ketones [Presence] in Urine by Test strip

518

1.78

2.60

4.5

3.1

0.00

estimate

-0.00

113

(3013707) Erythrocyte sedimentation rate by Westergren method

782

1.93

2.60

4.7

3.5

12.20

9.60

mm/h

0.98

724

(3046294) Neutrophil cytoplasmic Ab.classic [Titer] in Serum

7.37

2.57

1.4

—

(3003031) Transferrin.carbohydrate deficient.disialo/Transferrin.total in Serum or Plasma

155

2.03

2.56

1.5

1.55

1.36

0.79

136

(3026008) Bacteria identified in Urine by Culture

313

1.80

2.47

2.4

—

(40764999) Glomerular filtration rate/1.73 sq M.predicted [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (CKD-EPI)

112

974

2.27

2.37

11.9

9.4

90.35

91.06

ml/min/173m2

0.11

750

(3012516) Albumin [Mass/volume] in Urine

200

1.88

2.33

3.6

3.1

29.58

62.28

mg/l

0.95

115

(3013527) Hepatitis B virus core IgM Ab [Presence] in Serum

3.64

2.31

1.1

1.3

—

(3015399) Transferrin receptor.soluble [Mass/volume] in Serum or Plasma

242

1.81

2.29

2.1

1.8

2.73

2.83

mg/l

0.12

204

(3006315) Basophils [#/volume] in Blood

512

1.71

2.28

6.2

5.4

0.04

e9/l

0.10

454

(3020682) Albumin/Creatinine [Ratio] in Urine

210

1.85

2.26

4.5

3.5

4.32

9.43

mg/mmol

1.11

123

(3001604) Monocytes [#/volume] in Blood

513

1.70

2.25

6.2

5.3

0.55

0.53

e9/l

0.50

456

(3003510) Neisseria gonorrhoeae DNA [Presence] in Urine by NAA with probe detection

252

1.79

2.24

1.7

2.2

—

(3013115) Eosinophils [#/volume] in Blood

534

1.69

2.21

6.2

5.9

0.16

0.17

e9/l

0.45

477

(3037467) Urinalysis macro (dipstick) panel - Urine

757

1.78

2.20

5.2

3.8

—

(3013327) Hepatitis A virus IgM Ab [Presence] in Serum

4.44

2.17

1.0

1.1

—

(3032155) Metanephrine Free [Moles/volume] in Serum or Plasma

5.15

2.09

1.2

—

(3045783) Sodium and Potassium panel [Moles/volume] - Serum or Plasma

106

2.05

5.2

4.7

—

(3030408) 3-Methoxytyramine [Moles/volume] in Serum or Plasma

4.68

1.96

1.2

1.3

—

(3009035) Cobalamin (Vitamin B12) [Moles/volume] in Serum or Plasma

164

1.82

1.88

1.8

1.5

433.89

513.15

pmol/l

1.02

142

(40760892) CBC W Ordered Manual Differential panel - Blood

482

1.61

1.87

7.6

5.9

—

(3013650) Neutrophils [#/volume] in Blood by Automated count

600

1.61

1.84

8.5

8.4

4.05

4.02

e9/l

0.04

530

(40768804) Tissue Pathology biopsy report

428

1.60

1.82

2.3

1.8

—

(3004119) Hemoglobin [Mass/volume] in Venous blood

2.61

1.78

1.8

2.5

117.33

129.75

g/l

—

(3000494) Fungus identified in Specimen by Culture

105

1.95

1.74

1.7

1.4

—

(4200892) Spirometry reversibility

2.31

1.73

1.1

1.3

—

(3019198) Lymphocytes [#/volume] in Blood

537

1.57

1.72

6.3

5.3

2.09

2.08

e9/l

0.03

488

(3050380) Cytology report of Cervical or vaginal smear or scraping Cyto stain

2.22

1.72

1.4

1.3

—

(3016293) Bicarbonate [Moles/volume] in Serum or Plasma

2.63

1.71

3.9

5.1

25.67

24.27

mmol/l

—

(3024354) Oxygen [Partial pressure] in Venous blood

2.36

1.69

2.8

4.97

4.51

kpa

0.26

(3000991) Gas panel - Venous blood

2.36

1.69

5.6

8.8

—

(43534045) MCM6 gene c.-13910C>T and -13915T>G [Identifier] in Blood or Tissue by Molecular genetics method Nominal

2.08

1.67

1.0

—

(3029937) Albumin [Presence] in Urine by Test strip

273

1.62

1.63

4.6

3.2

0.00

estimate

-0.00

110

(3010380) Borrelia burgdorferi IgG Ab [Units/volume] in Cerebral spinal fluid

3.67

1.63

1.2

1.1

—

(3014973) Borrelia burgdorferi IgM Ab [Units/volume] in Cerebral spinal fluid

3.67

1.63

1.2

1.1

—

(3000492) Spirometry study

2.05

1.62

1.2

—

(40763086) Leukocyte esterase [Presence] in Urine by Automated test strip

391

1.56

1.61

4.0

3.0

—

(3024950) Chlamydia trachomatis DNA [Presence] in Urine by NAA with probe detection

283

1.60

1.8

2.4

—

(3018251) Fasting glucose [Moles/volume] in Serum or Plasma

110

989

1.84

1.53

5.2

3.6

5.76

5.67

mmol/l

0.40

105

921

(3049804) Myeloperoxidase IgG Ab [Units/volume] in Serum

2.95

1.52

3.5

1.5

—

(3002109) Cholesterol in LDL/Cholesterol in HDL [Mass Ratio] in Serum or Plasma

138

0.41

1.51

1.3

1.5

—

(3016251) Hemoglobin.gastrointestinal [Presence] in Stool

2.47

1.49

3.3

2.0

—

(3021447) Carbon dioxide [Partial pressure] in Venous blood

2.14

1.49

4.3

4.1

6.03

5.70

kpa

0.43

(3021589) Normoblasts [#/volume] in Blood

473

1.51

1.46

8.3

7.5

0.00

e9/l

-0.00

376

(3010566) Parathyrin.intact [Moles/volume] in Serum or Plasma

3.21

1.45

7.2

1.6

—

(3009201) Thyrotropin [Units/volume] in Serum or Plasma

113

1030

1.88

1.42

6.9

4.9

1.65

1.75

mu/l

0.64

108

960

(3007628) Bicarbonate [Moles/volume] standard in Venous blood

2.49

1.41

6.4

5.8

24.71

24.10

mmol/l

—

(3019832) Treponema pallidum Ab [Presence] in Serum

251

0.54

1.40

1.9

1.8

—

(3052851) Hemolysis interference index of Serum or Plasma

2.69

1.38

1.5

1.7

—

(3016650) Hepatitis A virus Ab [Presence] in Serum

3.02

1.37

1.0

1.1

—

(3021879) Hepatitis B virus core Ab [Presence] in Serum

107

1.79

1.34

1.3

1.4

—

(3021614) Rheumatoid factor [Units/volume] in Serum or Plasma

198

1.60

1.33

1.2

1.3

10.00

30.85

iu/ml

—

(3019060) Gas panel - Arterial blood

2.44

1.32

2.3

4.4

—

(3051552) Clostridioides difficile toxin genes [Presence] in Stool by NAA with probe detection

2.18

1.31

1.2

—

(46237023) Hepatitis B virus core and surface Ab and surface Ag panel - Serum

2.12

1.30

1.1

1.3

—

(3044640) Blood type and Crossmatch panel - Blood

325

1.49

1.25

1.8

2.0

—

(3044889) 12 lead EKG panel

622

1.45

1.24

3.8

3.0

—

(3044938) Influenza virus A RNA [Presence] in Specimen by NAA with probe detection

126

1.70

1.24

1.6

1.9

—

(3007853) Bacteria identified in Skin by Aerobe culture

102

1.77

1.24

1.5

1.4

—

(43054914) Glucose tolerance 2 hours panel - Serum or Plasma

159

1.63

1.23

2.0

—

(3020059) Calcium [Moles/volume] corrected for albumin in Serum or Plasma

159

1.63

1.23

3.0

2.2

2.44

2.43

mmol/l

0.18

140

(3050129) First trimester maternal screen panel - Serum or Plasma

110

0.43

1.20

1.6

1.5

—

(40768797) Stomach Pathology biopsy report

128

1.67

1.17

1.2

1.1

—

(3027315) Oxygen [Partial pressure] in Blood

2.56

1.16

3.8

2.6

9.16

9.49

kpa

—

(3013290) Carbon dioxide [Partial pressure] in Blood

2.56

1.16

3.8

2.6

4.88

5.03

kpa

—

(3022621) pH of Urine by Test strip

1.90

1.13

1.8

2.2

—

(3041096) Erythrocytes [Presence] in Urine by Automated

304

1.46

1.12

3.3

2.7

—

(3030905) Polymorphonuclear cells [#/volume] in Blood

2.44

1.10

3.2

2.7

4.03

4.29

e9/l

—

(3032035) Polymorphonuclear cells/100 leukocytes in Blood

2.44

1.10

3.4

3.6

58.20

58.10

—

(3023368) Bacteria identified in Blood by Culture

174

1.54

1.06

3.4

3.5

—

(40761536) Microorganisms panel - Urine sediment

1.71

1.02

5.7

2.9

—

(4034850) Laboratory test

2.06

1.01

6.3

—

(3022217) INR in Platelet poor plasma by Coagulation assay

338

1.41

1.00

9.9

8.8

1.25

1.10

inr

0.47

103

(3019902) Methicillin resistant Staphylococcus aureus [Presence] in Specimen by Organism specific culture

1.73

0.99

2.5

2.9

—

(3018006) Microscopic observation [Identifier] in Cervix by Cyto stain.thin prep

321

1.41

0.97

1.8

1.4

—

(3020460) C reactive protein [Mass/volume] in Serum or Plasma

114

1066

1.68

0.96

14.5

10.4

19.31

18.75

mg/l

0.06

797

(3024889) Methemoglobin/Hemoglobin.total in Venous blood

2.28

0.95

1.8

2.5

0.50

0.66

—

(3042936) Bacteria identified in Isolate by Culture

119

1.60

0.94

1.7

2.1

—

(3021584) Pregnancy associated plasma protein A [Units/volume] in Serum or Plasma

167

0.56

0.93

1.8

1.5

—

(3014051) Protein [Presence] in Urine by Test strip

2.20

0.93

2.7

1.7

—

(3016921) Smith extractable nuclear Ab [Units/volume] in Serum

2.20

0.93

1.3

1.4

—

2.13

—

(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection

892

1.43

0.90

3.7

3.9

—

(3006093) Chlamydia trachomatis DNA [Presence] in Specimen by NAA with probe detection

189

1.47

0.90

1.4

1.9

—

(1002224) Polysomnography panel

1.87

0.88

1.0

1.1

—

(3003191) Choriogonadotropin (pregnancy test) [Presence] in Serum or Plasma

1.64

0.85

1.9

1.8

—

(3014576) Chloride [Moles/volume] in Serum or Plasma

1.71

0.85

3.1

6.8

103.92

104.29

mmol/l

0.13

(3043924) Respiratory syncytial virus RNA [Identifier] in Specimen by NAA with probe detection

1.65

0.81

1.7

1.9

—

(3038288) Influenza virus B RNA [Presence] in Specimen by NAA with probe detection

1.63

0.78

1.8

2.0

—

(3036086) Jo-1 extractable nuclear Ab [Units/volume] in Serum by Immunoassay

2.22

0.77

1.4

1.3

—

(4094501) Cardiovascular stress test using bicycle ergometer

2.13

0.75

1.0

1.1

—

(3037522) Nuclear Ab [Titer] in Serum

152

1.46

0.75

1.5

613.33

525.41

titre

—

(3013512) EKG study

242

1.37

0.74

3.9

3.4

—

(3044290) Cell count panel - Cerebral spinal fluid

2.04

0.73

1.0

1.3

—

(3000330) Specific gravity of Urine by Test strip

1.66

0.68

1.7

2.0

—

(3003785) Carcinoembryonic Ag [Mass/volume] in Serum or Plasma

1.63

0.67

1.7

3.9

1.82

6.50

ug/l

—

(3004490) Bicarbonate [Moles/volume] standard in Capillary blood

1.82

0.67

5.6

5.1

25.64

24.24

mmol/l

—

(40761511) CBC panel - Blood by Automated count

118

1132

1.60

0.65

13.0

9.3

—

(3004529) Oxygen [Partial pressure] adjusted to patient's actual temperature in Venous blood

1.75

0.64

2.0

2.6

36.72

44.22

—

(3013139) Helicobacter pylori Ag [Presence] in Stool

1.60

0.64

1.5

1.2

—

(3033319) Streptococcus pyogenes Ag [Presence] in Throat

183

0.68

0.61

1.2

1.5

—

(3045424) Erythrocytes [Presence] in Urine

0.00

0.60

0.0

1.3

—

(3015024) Glucose [Moles/volume] in Serum or Plasma --1 hour post dose glucose

0.00

0.60

0.0

2.0

—

7.03

—

(40766183) Gliadin peptide IgA Ab [Units/volume] in Serum by Immunoassay

0.00

0.59

0.0

1.1

—

2.81

—

(3001019) Free T4 and TSH panel - Serum or Plasma

0.54

0.58

2.0

1.9

—

(3024135) Streptococcus.beta-hemolytic [Presence] in Throat by Organism specific culture

346

1.27

0.57

1.8

1.7

—

(3002434) Lupus erythematosus deoxynucleoproteins IgG Ab [Units/volume] in Serum by Immunoassay

1.65

0.56

1.3

2.0

—

(3016888) Borrelia burgdorferi IgG Ab [Units/volume] in Serum

1.53

0.55

1.3

1.2

—

42.96

—

(3011288) Drugs identified in Urine by Screen method

1.49

0.54

1.7

2.0

—

(3048816) Calcium.ionized [Moles/volume] adjusted to pH 7.4 in Blood

1.56

0.54

7.1

3.2

1.25

1.23

mmol/l

—

(3001079) Blood group antibody screen [Presence] in Serum or Plasma

513

1.24

0.54

2.3

2.4

—

(3011371) Neisseria gonorrhoeae DNA [Presence] in Specimen by NAA with probe detection

154

1.35

0.52

1.2

1.7

—

(3019800) Troponin T.cardiac [Mass/volume] in Serum or Plasma

302

1.27

0.52

3.7

2.9

13.63

21.36

ng/l

1.30

153

(1761868) Lipid panel - Serum or Plasma

390

0.79

0.50

2.1

2.4

—

(3004588) Protein electrophoresis panel - Serum or Plasma

1.59

0.50

1.3

3.3

—

(3000855) Microscopic observation [Identifier] in Vaginal fluid by Gram stain

1.55

0.49

2.4

1.5

—

(40768443) Skin Pathology biopsy report

1.55

0.49

1.3

1.2

—

(3021337) Troponin I.cardiac [Mass/volume] in Serum or Plasma

158

1.32

0.45

3.4

3.3

245.93

38.05

ng/l

0.42

(3049207) Fetal Trisomy 21 risk [Likelihood] Based on maternal age

0.62

0.44

1.7

1.5

—

(3008714) Choriogonadotropin [Multiple of the median] adjusted in Serum or Plasma

0.62

0.44

1.7

1.5

—

(40763531) Fetal Nuchal fold [Multiple of the median] Thickness adjusted for maternal weight

0.62

0.44

1.7

1.5

—

(46235831) Pregnancy associated plasma protein A [Multiple of the median] adjusted in Serum or Plasma

0.62

0.44

1.7

1.5

—

(3027273) Bicarbonate [Moles/volume] in Venous blood

1.58

0.42

1.4

2.6

22.84

24.21

mmol/l

—

(3022313) Gas panel - Capillary blood

1.54

0.42

5.4

4.4

—

(3019145) Choriogonadotropin.beta subunit free [Mass/volume] in Serum or Plasma

102

0.67

0.41

1.4

1.6

—

(3050238) Crystals [Presence] in Synovial fluid by Light microscopy

0.00

0.41

0.0

1.4

—

(3006588) Cancer Ag 15-3 [Units/volume] in Serum or Plasma

0.00

0.41

0.0

1.8

—

13.59

—

(3002385) Erythrocyte distribution width [Ratio]

102

973

1.25

0.39

17.3

12.9

14.36

14.40

0.03

102

966

(46236098) ABO and Rh group [Type] in Blood by Confirmatory method

255

1.23

0.39

1.5

1.8

—

(3007164) IgA [Mass/volume] in Serum or Plasma

293

1.22

0.39

1.5

1.3

1.93

2.06

g/l

0.28

171

(3008898) HLA-B27 [Presence]

1.37

0.39

1.0

1.1

—

(21494755) Public health laboratory ask at order entry panel

135

0.72

0.38

1.3

1.2

—

(3043238) Trisomy 21 risk [Likelihood] in Fetus

0.61

0.36

1.6

—

(3017895) Helicobacter pylori Ab [Units/volume] in Serum

1.32

0.33

2.0

1.7

—

(3045414) Leukocytes [Presence] in Urine

1.37

0.32

2.0

1.5

—

(46235355) HIV 1 and 2 tests - Meaningful Use set

371

0.85

0.29

2.1

—

(3027238) Thyroperoxidase Ab [Units/volume] in Serum or Plasma

103

1.29

0.29

1.3

191.83

113.32

iu/ml

—

(3029511) Human papilloma virus DNA [Presence] in Specimen by NAA with probe detection

1.24

0.29

1.6

1.7

—

(3019284) Hepatitis B virus surface Ag [Presence] in Serum

306

0.85

0.26

2.0

1.8

—

(3048689) Calprotectin [Mass/mass] in Stool

171

1.20

0.25

2.6

2.1

88.71

98.14

ug/g

0.05

130

(3041942) Cyclic citrullinated peptide Ab [Units/volume] in Serum

200

1.18

0.24

1.2

1.3

1.10

5.99

u/ml

—

(3003694) ABO and Rh group [Type] in Blood

377

1.13

0.21

1.7

—

(3004915) Chlamydophila pneumoniae IgA Ab [Units/volume] in Serum

0.00

0.21

0.0

1.0

—

(3005702) Mycobacterium sp identified in Specimen by Organism specific culture

0.00

0.21

0.0

1.3

—

(44813793) Dust mix specific IgE antibody measurement

0.00

0.21

0.0

1.1

—

(40765161) Human bocavirus DNA [Presence] in Specimen by NAA with probe detection

0.00

0.21

0.0

1.7

—

(3021788) Differential panel - Synovial fluid

0.00

0.21

0.0

1.4

—

(3019497) Choriogonadotropin.beta subunit free [Moles/volume] in Serum or Plasma

0.00

0.21

0.0

1.3

—

(3019897) Erythrocyte distribution width [Ratio] by Automated count

0.00

0.21

0.0

1.5

—

13.38

—

(36660697) Celiac disease serology panel - Serum

127

1.21

0.20

1.3

1.1

—

(3042194) Human metapneumovirus RNA [Presence] in Specimen by NAA with probe detection

0.00

0.20

0.0

1.7

—

(42529200) Cancer Ag 15-3 [Units/volume] in Serum or Plasma by Immunoassay

0.00

0.20

0.0

3.7

—

84.55

—

(3005570) Glucose [Moles/volume] in Urine

0.00

0.20

0.0

2.2

—

(3014162) Mycobacterium tuberculosis DNA [Presence] in Specimen by NAA with probe detection

0.00

0.20

0.0

2.6

—

(3019050) Tissue transglutaminase IgA Ab [Units/volume] in Serum

320

1.13

0.20

1.2

1.3

0.58

1.72

u/ml

1.39

(36032419) SARS-CoV-2 (COVID-19) Ag [Presence] in Upper respiratory specimen by Immunoassay

1.21

0.20

3.3

2.2

—

(3000963) Hemoglobin [Mass/volume] in Blood

120

1209

0.87

0.18

22.9

15.8

134.77

132.68

g/l

1.17

120

1191

(3035941) MCH [Entitic mass]

120

1208

0.88

0.17

22.6

15.6

29.77

30.08

1.06

120

1191

(3024731) MCV [Entitic volume]

120

1208

0.88

0.17

22.6

15.6

89.59

90.28

0.87

120

1191

(3005322) IgE [Units/volume] in Serum or Plasma

1.17

0.17

1.1

1.3

46.80

447.42

u/ml

—

(3020321) Streptococcus agalactiae [Presence] in Vaginal fluid by Organism specific culture

0.77

0.16

1.7

1.5

—

(3027944) Amphetamines [Presence] in Urine

0.76

0.16

3.0

1.7

—

(3004716) Salmonella sp identified in Stool by Organism specific culture

0.76

0.16

1.8

1.4

—

(36031861) Influenza virus A and B and SARS-CoV-2 (COVID-19) and Respiratory syncytial virus RNA panel - Respiratory system specimen by NAA with probe detection

1.17

0.10

2.4

1.9

—

(3046870) Tissue transglutaminase IgG Ab [Units/volume] in Serum

0.81

0.08

1.2

1.1

—

(3017143) Hepatitis C virus Ab [Presence] in Serum

176

1.09

0.08

1.8

1.6

—

(3023511) Choriogonadotropin [Units/volume] in Urine

1.03

0.08

1.4

1.2

—

(3022145) Colonoscopy Study observation

109

1.11

0.06

1.3

—

(3003338) MCHC [Mass/volume]

953

1.03

0.01

19.9

13.3

332.61

332.25

g/l

0.15

947

(3027008) Opiates [Presence] in Urine

0.89

0.00

2.7

1.7

—

(1001926) Buprenorphine [Presence] in Urine by Screen method

1.00

0.00

2.9

1.8

—

(3047189) Immunofixation for 24 hour Urine

0.00

-0.00

0.0

2.8

—

(3030692) Respiratory virus DNA+RNA [Identifier] in Specimen by NAA with probe detection

0.00

-0.00

0.0

2.3

—

(3024263) Appearance of Synovial fluid

0.00

-0.00

0.0

1.2

—

(3013005) Retinol [Moles/volume] in Serum or Plasma

0.00

-0.00

0.0

1.1

—

1.64

—

(37020937) Giardia lamblia DNA [Presence] in Stool by NAA with probe detection

0.00

-0.00

0.0

1.1

—

(3053028) Streptococcus sp identified in Specimen by Organism specific culture

0.00

-0.00

0.0

1.1

—

(3003245) Complement C1 esterase inhibitor [Mass/volume] in Serum or Plasma

0.00

-0.00

0.0

1.1

—

0.26

—

(3011363) Streptococcus pneumoniae Ag [Presence] in Urine

0.00

-0.00

0.0

1.2

—

(3006262) Parainfluenza virus 3 RNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

1.7

—

(3029396) Erythrocyte agglutination [Presence] in Blood

0.00

-0.00

0.0

4.5

—

(3005757) Coagulation factor V activity actual/normal in Platelet poor plasma by Coagulation assay

0.00

-0.00

0.0

1.0

—

112.20

—

(3000108) Respiratory syncytial virus B RNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

1.0

—

(3005156) Respiratory syncytial virus A RNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

1.0

—

(40758895) Direct antiglobulin test.complement C3d specific reagent [Presence] on Red Blood Cells

0.00

-0.00

0.0

1.6

—

(3025634) Parainfluenza virus 1 RNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

1.0

—

(3038297) Parainfluenza virus 4 RNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

1.0

—

(3042596) Human coronavirus RNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

1.7

—

(3012158) Parainfluenza virus 2 RNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

1.7

—

(3028300) Cannabinoids [Presence] in Urine

0.88

-0.00

2.7

1.7

—

(3022575) Varicella zoster virus IgG Ab [Units/volume] in Serum

0.00

-0.00

0.0

1.0

—

1884.20

—

(3021236) Streptolysin O Ab [Units/volume] in Serum or Plasma

0.00

-0.00

0.0

1.4

—

100.20

—

(3007847) Interleukin 2 Receptor Soluble [Units/volume] in Serum or Plasma

0.00

-0.00

0.0

3.2

—

699.80

—

(3045066) Thymidine kinase [Enzymatic activity/volume] in Serum

0.00

-0.00

0.0

1.0

—

43.62

—

(21493195) Respiratory pathogens DNA and RNA tested for in Respiratory system specimen by NAA with probe detection

0.00

-0.00

0.0

1.0

—

(3036071) Salmonella sp Ab [Titer] in Serum

0.00

-0.00

0.0

1.2

—

(3030558) Cytomegalovirus DNA [Units/volume] (viral load) in Specimen by NAA with probe detection

0.00

-0.00

0.0

1.2

—

(3000764) Benzodiazepines [Presence] in Urine

0.88

-0.00

2.7

1.7

—

(3013201) Beta-2-Microglobulin [Mass/volume] in Serum or Plasma

0.00

-0.00

0.0

1.8

—

4.51

—

(3007821) Glucose [Moles/volume] in Serum or Plasma --baseline

0.00

-0.00

0.0

1.2

—

5.30

—

(3034426) Prothrombin time (PT)

0.00

-0.00

0.0

1.0

—

(3038546) Human coronavirus OC43 RNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

1.6

—

(3016879) Cocaine [Presence] in Urine

0.93

-0.00

2.7

1.7

—

(3041642) Human coronavirus 229E RNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

1.6

—

(3044941) Cell count panel - Synovial fluid

0.00

-0.00

0.0

1.3

—

(40764126) Parainfluenza virus RNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

1.8

—

(40766048) U1 small nuclear ribonucleoprotein 70kD Ab [Units/volume] in Serum by Immunoassay

0.00

-0.00

0.0

1.2

—

(43055089) Myosin Ab [Presence] in Serum or Plasma by Immunoblot

0.00

-0.00

0.0

1.0

—

(40770918) von Willebrand factor (vWf).activity actual/normal in Platelet poor plasma by Immunoassay

0.00

-0.00

0.0

3.0

—

94.00

—

(3010254) Herpes simplex virus identified in Specimen by Organism specific culture

0.00

-0.00

0.0

1.0

—

(40768441) Liver Pathology biopsy report

0.00

-0.00

0.0

1.1

—

(21494670) JAK2 gene exon 14 targeted mutation analysis in Blood or Tissue by Molecular genetics method

0.00

-0.00

0.0

1.0

—

(3042631) Mycobacterium sp identified in Specimen

0.00

-0.00

0.0

4.4

—

(3005791) Eosinophil cationic protein (ECP) [Mass/volume] in Serum

0.00

-0.00

0.0

2.8

—

19.32

—

(4062490) Immunoglobulin typing, IgG

0.00

-0.00

0.0

1.4

—

(36305771) Cryptosporidium sp DNA [Presence] in Stool by NAA with probe detection

0.00

-0.00

0.0

1.1

—

(40763082) Lactate dehydrogenase [Enzymatic activity/volume] in Pleural fluid by Lactate to pyruvate reaction

0.00

-0.00

0.0

1.0

—

213.14

—

(3000208) Alpha tocopherol [Moles/volume] in Serum or Plasma

0.00

-0.00

0.0

1.0

—

29.60

—

(3003434) Protein [Mass/volume] in Pleural fluid

0.00

-0.00

0.0

1.2

—

29.00

—

(21491868) Cryoglobulin [Mass/volume] in Serum

0.00

-0.00

0.0

1.0

—

(3036782) Glucose [Moles/volume] in Pleural fluid

0.00

-0.00

0.0

1.0

—

6.30

—

(3040359) Human coronavirus NL63 RNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

1.6

—

(3020717) Zinc [Moles/volume] in Serum or Plasma

0.00

-0.00

0.0

1.0

—

41.32

—

(3028772) Osteocalcin [Mass/volume] in Serum or Plasma

0.00

-0.00

0.0

1.7

—

31757.86

—

(3046896) Herpes virus 6 DNA [Presence] in Cerebral spinal fluid by NAA with probe detection

0.00

-0.00

0.0

1.1

—

(3008364) Apolipoprotein A-I [Mass/volume] in Serum or Plasma

0.00

-0.00

0.0

1.3

—

1.58

—

(3012202) Varicella zoster virus DNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

1.0

—

(3019225) pH of Specimen

1.01

-0.00

3.8

—

(4035726) Immunohistochemistry procedure

0.99

-0.00

1.4

1.3

—

(3009595) Pneumocystis jiroveci DNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

1.2

—

(3011547) Coagulation factor VII activity actual/normal in Platelet poor plasma by Coagulation assay

0.00

-0.00

0.0

1.0

—

138.00

—

(3011831) Apolipoprotein B/Apolipoprotein A-I [Percentile]

0.00

-0.00

0.0

1.3

—

(3014791) Apolipoprotein B [Mass/volume] in Serum or Plasma

0.00

-0.00

0.0

1.3

—

0.95

—

(3024172) Erythropoietin (EPO) [Units/volume] in Serum or Plasma

0.00

-0.00

0.0

1.0

—

13.07

—

(40758897) Direct antiglobulin test.IgG specific reagent [Presence] on Red Blood Cells

0.00

-0.00

0.0

1.6

—

Mortality – FinRegistry

↥

Association

Association between endpoint L12_HYPERTICHNAS and mortality.

Females

No data

Males

No data

Mortality risk

Mortality risk for people of age

years, who have L12_HYPERTICHNAS.

N-year risk	Females	Males
1	No data	No data
5	No data	No data
10	No data	No data
15	No data	No data
20	No data	No data

Relationships between endpoints

↥

Index endpoint: L12_HYPERTICHNAS – Other hypertrichosis

GWS hits: 1

Endpoint

Case Overlap

Survival Analysis

Genetic Correlations

Genetic Signals

N (Jaccard index)

HR [CI]

rg [CI]

Hits

Coloc Hits

FinRegistry

FinnGen

FinRegistry

FinnGen

Loading data

Other hypertrichosis

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

1. Apply sex-specific rule

2. Check conditions

3. Check pre-conditions, main-only, mode, registry filters

4. Check minimum number of events

5. Include endpoints

6. Filter based on genotype QC (FinnGen only)

Similar endpoints

Case counts by codes

Summary Statistics

-FinRegistry-

Key figures

-FinnGen-

Key figures

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

Matched cohort

LabWAS

Mortality – FinRegistry

Association

Females

Males

Mortality risk

Relationships between endpoints