Other hypertrichosis

L12_HYPERTICHNAS

No definition available.

Endpoint definition

↥

Endpoint definition steps	FinnGen
Phenotype data	520210
1. Apply sex-specific rule None	520210
2. Check conditions None	520210
3. Check pre-conditions, main-only, mode, registry filters Registry filters: Hospital discharge: ICD-10 — L68.8, L68.9 Hospital discharge: ICD-9 — 7041C Hospital discharge: ICD-8 — 70405 Cause of death: ICD-10 — L68.8, L68.9 Cause of death: ICD-9 — 7041C Cause of death: ICD-8 — 70405 2 out of 7 registries used, show all original rules.	126
4. Check minimum number of events None	126
5. Include endpoints None	126
6. Filter based on genotype QC (FinnGen only)	126

Control definitions (FinnGen only)

Control exclude: L12_DISORDSKINAPPENDIX

Extra metadata

Level in the ICD hierarchy: 4
First used in FinnGen datafreeze: DF2

NAME	L12_HYPERTICHNAS
CONTROL_EXCLUDE	L12_DISORDSKINAPPENDIX
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX
INCLUDE
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10	L68[8-9]
HD_ICD_9	7041C
HD_ICD_8	70405
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10	L68[8-9]
COD_ICD_9	7041C
COD_ICD_8	70405
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

Similar endpoints

↥

List of similar endpoints to Other hypertrichosis based on the number of shared cases.

Similar with more cases:

Similar with less cases:

None

Case counts by codes

↥

FinnGen case counts by registry codes:

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

Key figures

	All	Female	Male
Number of individuals
Whole population	887	839	42
Only index persons	815	776	39
Unadjusted period prevalence (%)
Whole population	0.02	0.02	0.00
Only index persons	0.03	0.03	0.00
Median age at first event (years)
Whole population	27.97	28.09	25.14
Only index persons	28.02	28.20	24.35

-FinnGen-

Key figures

	All	Female	Male
Number of individuals	126	121	5
Unadjusted period prevalence (%)	0.04	0.04	0.00
Median age at first event (years)	30.26	30.32	28.90

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS (R11)

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log₁₀(p-value) ≥ 6.

Matched cohort

Matched cases
106: Matched controls
1061

Code

Vocabulary

Description

Odds Ratio

-log₁₀(p)

N matched cases

N matched controls

L68.9

ICD-10 Finland

Hypertrichosis, unspecified

+∞

68.3

L68.0

ICD-10 Finland

Hirsutism

+∞

35.4

70405

ICD-8 Finland

Diseases of hair and hair follicles, Hypertrichosis

+∞

28.4

L68.8

ICD-10 Finland

Other hypertrichosis

+∞

27.3

C03DA01

ATC

spironolactone; oral

9.9

12.3

E28.2

ICD-10 Finland

Polycystic ovarian syndrome

14.3

9.2

G03HB01

ATC

cyproterone and estrogen; systemic

4.5

8.8

100

E66.8

ICD-10 Finland

Other obesity

8.2

7.9

A10BA02

ATC

metformin; oral

3.7

6.8

111

E66.01

ICD-10 Finland

Obesity due to excess calories

4.7

6.3

E66.9

ICD-10 Finland

Obesity, unspecified

8.1

6.1

LabWAS

↥

(ID) Name

N Cases

N Controls

-log₁₀(p)

cases

controls

cases

controls

unit

-log₁₀(p)

N cases

N controls

(3009214) Lutropin [Units/volume] in Serum or Plasma

7.57

15.17

1.6

1.3

10.2

8.8

u/l

0.23

(3021387) Prolactin [Units/volume] in Serum or Plasma

5.65

13.68

1.7

1.4

266.0

262.2

mu/l

0.04

(3004248) Sex hormone binding globulin [Moles/volume] in Serum or Plasma

30.19

12.39

1.4

1.3

42.5

30.3

nmol/l

—

(3023530) 17-Hydroxyprogesterone [Moles/volume] in Serum or Plasma

+∞

7.36

1.6

0.0

2.1

—

nmol/l

—

(40763571) Iron/Transferrin [Ratio] in Serum or Plasma

2.90

4.83

4.2

2.3

25.1

23.0

0.18

(3035637) Corticotropin [Mass/volume] in Plasma

7.98

4.43

3.8

1.8

—

(3029287) Urinalysis microscopic panel [#/volume] - Urine by Automated count

320

2.20

4.39

4.1

3.0

—

(3030467) Casts [#/volume] in Urine by Automated count

258

2.23

4.26

4.4

2.7

0.2

0.4

e6/l

0.49

184

(36304419) Bacteria [Presence] in Urine

263

2.18

4.03

4.3

2.6

—

(3015377) Calcium [Moles/volume] in Serum or Plasma

307

2.04

3.57

2.9

2.5

2.4

2.3

mmol/l

0.59

274

(3002582) Erythrocytes [#/volume] in Urine

286

2.03

3.41

4.5

3.1

12.9

71.4

e6/l

1.60

211

(43054903) Holo-transcobalamin II [Moles/volume] in Serum

374

1.96

3.33

2.1

1.8

102.6

95.4

pmol/l

0.63

187

(3030306) Epithelial cells.non-squamous [#/volume] in Urine by Automated count

155

2.23

3.31

3.4

2.4

0.8

0.9

e6/l

0.05

(3018095) Leukocytes [#/volume] in Urine

358

1.95

3.27

5.6

3.7

31.0

65.6

e6/l

0.60

227

(3018418) pH of Serum or Plasma

275

1.99

3.20

4.7

4.0

7.4

—

(44816844) Macroprolactin [Units/volume] in Serum or Plasma

4.76

3.18

1.7

1.2

—

(3003458) Phosphate [Moles/volume] in Serum or Plasma

2.40

2.97

7.1

6.2

1.0

1.1

mmol/l

0.37

(3051714) Fibrin D-dimer FEU [Mass/volume] in Platelet poor plasma

225

1.99

2.92

1.9

2.0

0.8

0.7

mg/l

0.08

173

(40761535) Cells panel - Urine sediment

2.66

2.74

2.7

3.1

—

(3013707) Erythrocyte sedimentation rate by Westergren method

778

1.98

2.72

4.7

3.6

12.2

9.6

mm/h

1.00

721

(3009261) Glucose [Presence] in Urine by Test strip

524

1.81

2.71

4.6

3.2

0.0

estimate

0.00

106

(3029879) Epithelial cells.squamous [#/volume] in Urine by Automated count

152

2.08

2.71

3.5

2.5

2.9

4.1

e6/l

0.38

(40758558) Short blood count panel - Blood

272

1.88

2.70

4.6

6.4

—

(3021601) Nitrite [Presence] in Urine by Test strip

515

1.81

2.69

5.9

4.4

0.0

estimate

0.00

110

(3035350) Ketones [Presence] in Urine by Test strip

517

1.80

2.64

4.5

3.1

0.0

estimate

0.00

105

(3026008) Bacteria identified in Urine by Culture

309

1.83

2.60

2.4

—

(3011397) Hemoglobin [Presence] in Urine by Test strip

226

1.90

2.57

4.8

3.1

—

(3002256) Pathology report gross observation

111

2.19

2.55

1.1

—

(3026493) Urate [Moles/volume] in Serum or Plasma

204

1.91

2.48

3.1

3.2

350.9

5859.5

umol/l

1.02

177

(40764999) Glomerular filtration rate/1.73 sq M.predicted [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (CKD-EPI)

111

961

2.30

2.44

12.0

9.3

90.3

90.8

ml/min/173m2

0.07

738

(3013527) Hepatitis B virus core IgM Ab [Presence] in Serum

3.81

2.41

1.1

1.3

—

(3012516) Albumin [Mass/volume] in Urine

199

1.89

2.37

3.6

3.1

29.6

62.3

mg/l

0.95

115

(3003031) Transferrin.carbohydrate deficient.disialo/Transferrin.total in Serum or Plasma

153

1.97

2.32

1.6

1.5

1.6

1.4

0.81

134

(3020682) Albumin/Creatinine [Ratio] in Urine

209

1.86

2.30

4.5

3.6

4.3

9.5

mg/mmol

1.11

122

(3037467) Urinalysis macro (dipstick) panel - Urine

754

1.82

2.29

5.2

3.8

—

(3006315) Basophils [#/volume] in Blood

513

1.71

2.26

6.2

5.5

0.0

e9/l

0.09

454

(3015399) Transferrin receptor.soluble [Mass/volume] in Serum or Plasma

243

1.81

2.26

2.1

1.9

2.7

2.8

mg/l

0.11

206

(3003510) Neisseria gonorrhoeae DNA [Presence] in Urine by NAA with probe detection

252

1.79

2.24

1.7

2.2

—

(3001604) Monocytes [#/volume] in Blood

514

1.70

2.24

6.2

5.4

0.6

0.5

e9/l

0.51

454

(3013115) Eosinophils [#/volume] in Blood

535

1.69

2.20

6.2

6.0

0.2

e9/l

0.42

478

(3013327) Hepatitis A virus IgM Ab [Presence] in Serum

4.44

2.17

1.0

1.1

—

(42870588) Differential panel, method unspecified - Blood

317

1.71

2.10

6.1

5.0

—

(3045783) Sodium and Potassium panel [Moles/volume] - Serum or Plasma

105

2.08

2.10

5.2

4.7

—

(3032155) Metanephrine Free [Moles/volume] in Serum or Plasma

5.15

2.09

1.2

—

(3030408) 3-Methoxytyramine [Moles/volume] in Serum or Plasma

4.68

1.96

1.2

1.3

—

(3009035) Cobalamin (Vitamin B12) [Moles/volume] in Serum or Plasma

164

1.82

1.88

1.8

1.5

433.9

512.2

pmol/l

1.00

142

(40768804) Tissue Pathology biopsy report

426

1.62

1.87

2.3

1.8

—

(3015736) pH of Urine

408

1.62

1.86

4.4

2.9

—

(3013650) Neutrophils [#/volume] in Blood by Automated count

600

1.62

1.85

8.5

4.0

e9/l

0.06

530

(3016293) Bicarbonate [Moles/volume] in Serum or Plasma

2.56

1.80

3.9

5.2

25.7

24.2

mmol/l

—

(3004119) Hemoglobin [Mass/volume] in Venous blood

2.61

1.78

1.8

2.5

117.3

129.8

g/l

—

(3000492) Spirometry study

2.11

1.73

1.2

—

(3050380) Cytology report of Cervical or vaginal smear or scraping Cyto stain

2.22

1.72

1.4

1.3

—

(3019198) Lymphocytes [#/volume] in Blood

538

1.57

1.71

6.2

5.4

2.1

e9/l

0.02

484

(3000494) Fungus identified in Specimen by Culture

106

1.93

1.70

1.7

1.4

—

(3000991) Gas panel - Venous blood

2.36

1.69

5.6

9.6

—

(43534045) MCM6 gene c.-13910C>T and -13915T>G [Identifier] in Blood or Tissue by Molecular genetics method Nominal

2.08

1.67

1.0

—

(4010399)

2.26

1.67

1.1

1.3

—

(3010380) Borrelia burgdorferi IgG Ab [Units/volume] in Cerebral spinal fluid

3.67

1.63

1.2

1.1

—

(3014973) Borrelia burgdorferi IgM Ab [Units/volume] in Cerebral spinal fluid

3.67

1.63

1.2

1.1

—

(3024354) Oxygen [Partial pressure] in Venous blood

2.31

1.62

2.8

3.6

5.0

4.5

kpa

0.24

(40763086) Leukocyte esterase [Presence] in Urine by Automated test strip

391

1.56

1.61

4.0

3.0

—

(3029937) Albumin [Presence] in Urine by Test strip

274

1.61

4.6

3.2

0.0

estimate

0.00

110

(3024950) Chlamydia trachomatis DNA [Presence] in Urine by NAA with probe detection

283

1.61

1.60

1.8

2.4

—

(3002109) Cholesterol in LDL/Cholesterol in HDL [Mass Ratio] in Serum or Plasma

136

0.41

1.51

1.3

1.5

—

(3016251) Hemoglobin.gastrointestinal [Presence] in Stool

2.54

1.51

3.3

2.0

—

(3021447) Carbon dioxide [Partial pressure] in Venous blood

2.14

1.49

4.3

4.7

6.0

5.7

kpa

0.44

(3018251) Fasting glucose [Moles/volume] in Serum or Plasma

109

982

1.82

1.48

5.3

3.6

5.8

5.7

mmol/l

0.43

104

915

(3021879) Hepatitis B virus core Ab [Presence] in Serum

104

1.85

1.46

1.3

1.4

—

(3021589) Normoblasts [#/volume] in Blood

474

1.51

1.45

8.3

7.6

0.0

e9/l

0.00

377

(3049804) Myeloperoxidase IgG Ab [Units/volume] in Serum

2.81

1.45

3.5

1.5

—

(3010566) Parathyrin.intact [Moles/volume] in Serum or Plasma

3.21

1.45

7.2

1.6

—

(3022217) INR in Platelet poor plasma by Coagulation assay

1.94

1.43

15.5

18.6

—

1.2

—

(3019832) Treponema pallidum Ab [Presence] in Serum

250

0.55

1.38

1.9

1.8

—

(3052851) Hemolysis interference index of Serum or Plasma

2.69

1.38

1.7

—

(3051552) Clostridioides difficile toxin genes [Presence] in Stool by NAA with probe detection

2.22

1.37

1.2

—

(3016650) Hepatitis A virus Ab [Presence] in Serum

3.02

1.37

1.0

1.1

—

(46237023) Hepatitis B virus core and surface Ab and surface Ag panel - Serum

2.23

1.37

1.1

1.3

—

(3005719) IgG [Mass/volume] in Serum or Plasma

1.89

1.34

3.3

2.3

9.1

10.1

g/l

0.83

(3021614) Rheumatoid factor [Units/volume] in Serum or Plasma

198

1.60

1.33

1.2

1.3

10.0

28.1

iu/ml

—

(3019060) Gas panel - Arterial blood

2.44

1.32

2.3

4.4

—

(3009201) Thyrotropin [Units/volume] in Serum or Plasma

112

1026

1.82

1.30

6.9

4.9

1.7

mu/l

0.55

107

958

(3044889) 12 lead EKG panel

621

1.46

1.27

3.8

3.0

—

(3020059) Calcium [Moles/volume] corrected for albumin in Serum or Plasma

158

1.64

1.26

3.0

2.2

2.4

mmol/l

0.15

139

(3044938) Influenza virus A RNA [Presence] in Specimen by NAA with probe detection

126

1.70

1.24

1.7

1.9

—

(43054914) Glucose tolerance 2 hours panel - Serum or Plasma

159

1.63

1.24

2.0

—

(3050129) First trimester maternal screen panel - Serum or Plasma

110

0.43

1.20

1.6

1.5

—

(3027315) Oxygen [Partial pressure] in Blood

2.56

1.16

3.8

2.6

9.2

9.5

kpa

—

(3013290) Carbon dioxide [Partial pressure] in Blood

2.56

1.16

3.8

2.6

4.9

5.0

kpa

—

(3041096) Erythrocytes [Presence] in Urine by Automated

303

1.47

1.14

3.3

2.7

—

(40768797) Stomach Pathology biopsy report

129

1.65

1.14

1.2

1.1

—

(3022621) pH of Urine by Test strip

1.90

1.13

1.8

2.2

—

(3007853) Bacteria identified in Skin by Aerobe culture

105

1.72

1.13

1.5

1.4

—

(3032035) Polymorphonuclear cells/100 leukocytes in Blood

2.44

1.10

3.4

3.6

58.2

58.1

—

(3030905) Polymorphonuclear cells [#/volume] in Blood

2.44

1.10

3.2

2.7

4.0

4.3

e9/l

—

(3044640) Blood type and Crossmatch panel - Blood

324

1.44

1.09

1.7

2.0

—

(3023368) Bacteria identified in Blood by Culture

175

1.53

1.03

3.4

3.5

—

(40761536) Microorganisms panel - Urine sediment

1.72

1.02

5.7

2.9

—

(4034850)

2.06

1.01

6.3

—

(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection

887

1.47

0.99

3.7

3.9

—

(3018006) Microscopic observation [Identifier] in Cervix by Cyto stain.thin prep

320

1.42

0.99

1.8

1.4

—

(3019902) Methicillin resistant Staphylococcus aureus [Presence] in Specimen by Organism specific culture

1.73

0.99

2.6

2.9

—

(3024889) Methemoglobin/Hemoglobin.total in Venous blood

2.28

0.95

1.8

2.5

0.5

0.7

—

(3042936) Bacteria identified in Isolate by Culture

119

1.60

0.94

1.7

2.1

—

(3020460) C reactive protein [Mass/volume] in Serum or Plasma

113

1059

1.65

0.91

14.6

10.5

19.3

18.8

mg/l

0.06

794

(3006093) Chlamydia trachomatis DNA [Presence] in Specimen by NAA with probe detection

189

1.47

0.91

1.4

2.0

—

(1002224) Polysomnography panel

1.92

0.89

1.0

1.1

—

(3014576) Chloride [Moles/volume] in Serum or Plasma

1.74

0.89

3.1

6.6

103.9

104.2

mmol/l

0.10

(3016921) Smith extractable nuclear Ab [Units/volume] in Serum

2.05

0.88

1.3

1.4

—

2.1

—

(3003191) Choriogonadotropin (pregnancy test) [Presence] in Serum or Plasma

1.64

0.85

1.9

1.8

—

(3043924) Respiratory syncytial virus RNA [Identifier] in Specimen by NAA with probe detection

1.65

0.82

1.7

1.9

—

(3038288) Influenza virus B RNA [Presence] in Specimen by NAA with probe detection

1.63

0.78

1.8

2.0

—

(3013512) EKG study

240

1.39

0.78

3.9

3.4

—

(4094501)

2.13

0.75

1.0

1.1

—

(3003785) Carcinoembryonic Ag [Mass/volume] in Serum or Plasma

1.68

0.74

1.7

4.0

1.8

6.7

ug/l

—

(3036086) Jo-1 extractable nuclear Ab [Units/volume] in Serum by Immunoassay

2.04

0.73

1.4

1.3

—

(3014051) Protein [Presence] in Urine by Test strip

2.04

0.73

2.0

1.6

—

(3044290) Cell count panel - Cerebral spinal fluid

2.04

0.73

1.0

1.3

—

(3037522) Nuclear Ab [Titer] in Serum

153

1.45

0.73

1.5

613.3

525.4

titre

—

(3021584) Pregnancy associated plasma protein A [Units/volume] in Serum or Plasma

167

0.63

0.72

1.7

1.5

—

(3000330) Specific gravity of Urine by Test strip

1.66

0.68

1.7

2.0

—

(3004490) Bicarbonate [Moles/volume] standard in Capillary blood

1.82

0.67

5.6

7.4

25.6

24.1

mmol/l

—

(3004588) Protein electrophoresis panel - Serum or Plasma

1.62

0.66

1.3

2.8

—

(40761511) CBC panel - Blood by Automated count

117

1124

1.57

0.65

13.1

9.4

—

(3004529) Oxygen [Partial pressure] adjusted to patient's actual temperature in Venous blood

1.75

0.64

2.0

2.6

36.7

44.2

—

(3032080) INR in Blood by Coagulation assay

286

1.31

0.62

5.5

5.0

1.3

1.1

inr

0.50

(3013139) Helicobacter pylori Ag [Presence] in Stool

1.58

0.61

1.5

1.2

—

(3024135) Streptococcus.beta-hemolytic [Presence] in Throat by Organism specific culture

344

1.28

0.60

1.8

1.7

—

(40766183) Gliadin peptide IgA Ab [Units/volume] in Serum by Immunoassay

0.00

0.60

0.0

1.1

—

2.8

—

(3015024) Glucose [Moles/volume] in Serum or Plasma --1 hour post dose glucose

0.00

0.60

0.0

2.0

—

6.9

—

(3045424) Erythrocytes [Presence] in Urine

0.00

0.60

0.0

1.3

—

(3001019) Free T4 and TSH panel - Serum or Plasma

0.56

0.58

2.0

1.9

—

(3016888) Borrelia burgdorferi IgG Ab [Units/volume] in Serum

1.56

0.58

1.3

1.2

—

43.0

—

(3011288) Drugs identified in Urine by Screen method

1.51

0.55

1.7

2.0

—

(3002434) Lupus erythematosus deoxynucleoproteins IgG Ab [Units/volume] in Serum by Immunoassay

1.61

0.55

1.3

2.1

—

(3033319) Streptococcus pyogenes Ag [Presence] in Throat

179

0.69

0.55

1.2

1.5

—

(3048816) Calcium.ionized [Moles/volume] adjusted to pH 7.4 in Blood

1.56

0.54

7.1

3.2

1.3

1.2

mmol/l

—

(3019800) Troponin T.cardiac [Mass/volume] in Serum or Plasma

301

1.27

0.54

3.7

2.9

13.6

21.4

ng/l

1.30

153

(3011371) Neisseria gonorrhoeae DNA [Presence] in Specimen by NAA with probe detection

154

1.36

0.52

1.2

1.7

—

(40768443) Skin Pathology biopsy report

1.55

0.49

1.3

1.2

—

(3000855) Microscopic observation [Identifier] in Vaginal fluid by Gram stain

1.55

0.49

2.4

1.5

—

(1761868) Lipid panel - Serum or Plasma

386

0.80

0.46

2.1

2.4

—

(40760892) CBC W Ordered Manual Differential panel - Blood

260

1.26

0.45

6.3

5.1

—

(3021337) Troponin I.cardiac [Mass/volume] in Serum or Plasma

158

1.32

0.45

3.4

3.3

245.9

38.0

ng/l

0.42

(40763531) Fetal Nuchal fold [Multiple of the median] Thickness adjusted for maternal weight

0.62

0.44

1.7

1.5

—

(3008714) Choriogonadotropin [Multiple of the median] adjusted in Serum or Plasma

0.62

0.44

1.7

1.5

—

(3049207) Fetal Trisomy 21 risk [Likelihood] Based on maternal age

0.62

0.44

1.7

1.5

—

(46235831) Pregnancy associated plasma protein A [Multiple of the median] adjusted in Serum or Plasma

0.62

0.44

1.7

1.5

—

(3001079) Blood group antibody screen [Presence] in Serum or Plasma

513

1.20

0.43

3.6

3.7

—

(3027273) Bicarbonate [Moles/volume] in Venous blood

1.59

0.42

1.4

2.6

22.8

24.2

mmol/l

—

(3007164) IgA [Mass/volume] in Serum or Plasma

291

1.23

0.42

1.5

1.3

1.9

2.1

g/l

0.29

170

(3022313) Gas panel - Capillary blood

1.54

0.42

5.4

6.4

—

(3019145) Choriogonadotropin.beta subunit free [Mass/volume] in Serum or Plasma

102

0.67

0.41

1.4

1.6

—

(3050238) Crystals [Presence] in Synovial fluid by Light microscopy

0.00

0.41

0.0

1.4

—

(3006588) Cancer Ag 15-3 [Units/volume] in Serum or Plasma

0.00

0.41

0.0

1.7

—

13.6

—

(46236098) ABO and Rh group [Type] in Blood by Confirmatory method

254

1.24

0.40

1.5

1.8

—

(3008898) HLA-B27 [Presence]

1.39

0.39

1.0

1.1

—

(3043238) Trisomy 21 risk [Likelihood] in Fetus

0.61

0.36

1.6

—

(3017895) Helicobacter pylori Ab [Units/volume] in Serum

1.38

0.35

2.0

1.7

—

(21494755) Public health laboratory ask at order entry panel

131

0.74

0.32

1.3

1.2

—

(3002385) Erythrocyte distribution width [Ratio]

938

1.20

0.32

17.8

13.1

13.5

13.4

0.17

930

(3045414) Leukocytes [Presence] in Urine

1.37

0.32

2.0

1.5

—

(3027238) Thyroperoxidase Ab [Units/volume] in Serum or Plasma

103

1.29

0.29

1.3

191.8

114.8

iu/ml

—

(3029511) Human papilloma virus DNA [Presence] in Specimen by NAA with probe detection

1.24

0.29

1.6

1.7

—

(46235355) HIV 1 and 2 tests - Meaningful Use set

369

0.86

0.28

2.1

—

(3041942) Cyclic citrullinated peptide Ab [Units/volume] in Serum

200

1.18

0.24

1.2

1.3

1.1

6.1

u/ml

—

(3048689) Calprotectin [Mass/mass] in Stool

172

1.19

0.24

2.6

2.1

88.7

98.3

ug/g

0.05

129

(3019284) Hepatitis B virus surface Ag [Presence] in Serum

303

0.86

0.23

2.0

1.8

—

(3003694) ABO and Rh group [Type] in Blood

377

1.13

0.21

1.7

—

(3004915) Chlamydophila pneumoniae IgA Ab [Units/volume] in Serum

0.00

0.21

0.0

1.0

—

(44813793)

0.00

0.21

0.0

1.1

—

(3005702) Mycobacterium sp identified in Specimen by Organism specific culture

0.00

0.21

0.0

1.3

—

(3021788) Differential panel - Synovial fluid

0.00

0.21

0.0

1.4

—

(40765161) Human bocavirus DNA [Presence] in Specimen by NAA with probe detection

0.00

0.21

0.0

1.7

—

(3019050) Tissue transglutaminase IgA Ab [Units/volume] in Serum

319

1.13

0.21

1.2

1.3

0.6

1.7

u/ml

1.39

(3019497) Choriogonadotropin.beta subunit free [Moles/volume] in Serum or Plasma

0.00

0.21

0.0

1.3

—

(3019897) Erythrocyte distribution width [Ratio] by Automated count

0.00

0.21

0.0

1.5

—

13.4

—

(3042194) Human metapneumovirus RNA [Presence] in Specimen by NAA with probe detection

0.00

0.21

0.0

1.8

—

(42529200) Cancer Ag 15-3 [Units/volume] in Serum or Plasma by Immunoassay

0.00

0.20

0.0

3.7

—

84.5

—

(3014162) Mycobacterium tuberculosis DNA [Presence] in Specimen by NAA with probe detection

0.00

0.20

0.0

2.6

—

(3005570) Glucose [Moles/volume] in Urine

0.00

0.20

0.0

2.2

—

(36660697) Celiac disease serology panel - Serum

128

1.20

0.19

1.3

1.1

—

(3000963) Hemoglobin [Mass/volume] in Blood

119

1200

0.85

0.18

23.0

16.0

134.7

132.6

g/l

1.19

119

1183

(3035941) MCH [Entitic mass]

119

1199

0.86

0.18

22.8

15.8

29.8

30.1

1.14

119

1183

(3024731) MCV [Entitic volume]

119

1199

0.86

0.18

22.8

15.8

89.6

90.3

0.94

119

1183

(3005322) IgE [Units/volume] in Serum or Plasma

1.17

0.17

1.1

1.3

46.8

447.4

u/ml

—

(3020321) Streptococcus agalactiae [Presence] in Vaginal fluid by Organism specific culture

0.77

0.16

1.7

1.5

—

(3004716) Salmonella sp identified in Stool by Organism specific culture

0.77

0.16

1.8

1.4

—

(3027944) Amphetamines [Presence] in Urine

0.77

0.16

3.0

1.7

—

(3017143) Hepatitis C virus Ab [Presence] in Serum

173

1.12

0.11

1.8

1.6

—

(36031861) Influenza virus A and B and SARS-CoV-2 (COVID-19) and Respiratory syncytial virus RNA panel - Respiratory system specimen by NAA with probe detection

1.14

0.10

2.4

1.9

—

(3022145) Colonoscopy Study observation

107

1.13

0.09

1.3

—

(3046870) Tissue transglutaminase IgG Ab [Units/volume] in Serum

0.81

0.08

1.2

1.1

—

(3009542) Hematocrit [Volume Fraction] of Blood

101

1004

1.03

0.00

16.1

11.1

40.2

39.6

0.50

818

(3003338) MCHC [Mass/volume]

947

1.01

0.00

20.0

13.4

332.5

332.2

g/l

0.12

941

(1001926) Buprenorphine [Presence] in Urine by Screen method

1.02

0.00

2.9

1.8

—

(3023511) Choriogonadotropin [Units/volume] in Urine

1.02

0.00

1.4

1.2

—

(3025634) Parainfluenza virus 1 RNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.0

—

(3005757) Coagulation factor V activity actual/normal in Platelet poor plasma by Coagulation assay

0.00

0.0

5.5

—

103.5

—

(3034426) Prothrombin time (PT)

0.00

0.0

1.0

—

(3020717) Zinc [Moles/volume] in Serum or Plasma

0.00

0.0

1.0

—

41.3

—

(3036071) Salmonella sp Ab [Titer] in Serum

0.00

0.0

1.2

—

(3014791) Apolipoprotein B [Mass/volume] in Serum or Plasma

0.00

0.0

1.3

—

0.9

—

(3007821) Glucose [Moles/volume] in Serum or Plasma --baseline

0.00

0.0

1.2

—

5.3

—

(3044941) Cell count panel - Synovial fluid

0.00

0.0

1.3

—

(21491868) Cryoglobulin [Mass/volume] in Serum

0.00

0.0

1.0

—

(3046896) Herpes virus 6 DNA [Presence] in Cerebral spinal fluid by NAA with probe detection

0.00

0.0

1.1

—

(3024172) Erythropoietin (EPO) [Units/volume] in Serum or Plasma

0.00

0.0

1.0

—

13.1

—

(3027008) Opiates [Presence] in Urine

0.90

0.00

2.7

1.7

—

(3042631) Mycobacterium sp identified in Specimen

0.00

0.0

4.5

—

(3028300) Cannabinoids [Presence] in Urine

0.89

0.00

2.7

1.7

—

(3041642) Human coronavirus 229E RNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.6

—

(3012202) Varicella zoster virus DNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.0

—

(3038297) Parainfluenza virus 4 RNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.0

—

(3013005) Retinol [Moles/volume] in Serum or Plasma

0.00

0.0

1.6

—

1.7

—

(40764126) Parainfluenza virus RNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.8

—

(3006262) Parainfluenza virus 3 RNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.0

—

(3003434) Protein [Mass/volume] in Pleural fluid

0.00

0.0

1.2

—

29.0

—

(4062490)

0.00

0.0

1.4

—

(3011363) Streptococcus pneumoniae Ag [Presence] in Urine

0.00

0.0

1.2

—

(3000108) Respiratory syncytial virus B RNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.0

—

(3011547) Coagulation factor VII activity actual/normal in Platelet poor plasma by Coagulation assay

0.00

0.0

1.0

—

138.0

—

(36305771) Cryptosporidium sp DNA [Presence] in Stool by NAA with probe detection

0.00

0.0

1.1

—

(40766048) U1 small nuclear ribonucleoprotein 70kD Ab [Units/volume] in Serum by Immunoassay

0.00

0.0

1.2

—

(3024263) Appearance of Synovial fluid

0.00

0.0

1.8

—

(3030692) Respiratory virus DNA+RNA [Identifier] in Specimen by NAA with probe detection

0.00

0.0

2.3

—

(21494670) JAK2 gene exon 14 targeted mutation analysis in Blood or Tissue by Molecular genetics method

0.00

0.0

1.0

—

(3007847) Interleukin 2 Receptor Soluble [Units/volume] in Serum or Plasma

0.00

0.0

3.2

—

699.8

—

(3047189) Immunofixation for 24 hour Urine

0.00

0.0

3.0

—

(3000208) Alpha tocopherol [Moles/volume] in Serum or Plasma

0.00

0.0

2.0

—

28.2

—

(3011831) Apolipoprotein B/Apolipoprotein A-I [Percentile]

0.00

0.0

1.4

—

(3022575) Varicella zoster virus IgG Ab [Units/volume] in Serum

0.00

0.0

1.0

—

1884.2

—

(3005156) Respiratory syncytial virus A RNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.0

—

(3012158) Parainfluenza virus 2 RNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.0

—

(40763082) Lactate dehydrogenase [Enzymatic activity/volume] in Pleural fluid by Lactate to pyruvate reaction

0.00

0.0

1.0

—

213.1

—

(3000764) Benzodiazepines [Presence] in Urine

0.89

0.00

2.7

1.7

—

(3045066) Thymidine kinase [Enzymatic activity/volume] in Serum

0.00

0.0

1.0

—

43.6

—

(3029396) Erythrocyte agglutination [Presence] in Blood

0.00

0.0

4.5

—

(3003245) Complement C1 esterase inhibitor [Mass/volume] in Serum or Plasma

0.00

0.0

1.1

—

0.3

—

(3005791) Eosinophil cationic protein (ECP) [Mass/volume] in Serum

0.00

0.0

2.8

—

19.3

—

(3021236) Streptolysin O Ab [Units/volume] in Serum or Plasma

0.00

0.0

1.4

—

100.2

—

(37020937) Giardia lamblia DNA [Presence] in Stool by NAA with probe detection

0.00

0.0

1.1

—

(3008364) Apolipoprotein A-I [Mass/volume] in Serum or Plasma

0.00

0.0

1.3

—

(3042596) Human coronavirus RNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.8

—

(36032419) SARS-CoV-2 (COVID-19) Ag [Presence] in Upper respiratory specimen by Immunoassay

1.00

0.00

3.6

2.2

—

(3010254) Herpes simplex virus identified in Specimen by Organism specific culture

0.00

0.0

1.0

—

(40768441) Liver Pathology biopsy report

0.00

0.0

1.3

—

(21493195) Respiratory pathogens DNA and RNA tested for in Respiratory system specimen by NAA with probe detection

0.00

0.0

1.0

—

(3036782) Glucose [Moles/volume] in Pleural fluid

0.00

0.0

1.0

—

6.3

—

(3019225) pH of Specimen

1.01

0.00

3.8

4.2

—

(3009595) Pneumocystis jiroveci DNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.2

—

(3013201) Beta-2-Microglobulin [Mass/volume] in Serum or Plasma

0.00

0.0

1.9

—

4.8

—

(40770918) von Willebrand factor (vWf).activity actual/normal in Platelet poor plasma by Immunoassay

0.00

0.0

3.0

—

94.0

—

(3040359) Human coronavirus NL63 RNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.6

—

(40758895) Direct antiglobulin test.complement C3d specific reagent [Presence] on Red Blood Cells

0.00

0.0

1.6

—

(3016879) Cocaine [Presence] in Urine

0.94

0.00

2.7

1.7

—

(3038546) Human coronavirus OC43 RNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.6

—

(4035726)

0.99

0.00

1.4

1.3

—

(3053028) Streptococcus sp identified in Specimen by Organism specific culture

0.00

0.0

1.1

—

(40758897) Direct antiglobulin test.IgG specific reagent [Presence] on Red Blood Cells

0.00

0.0

1.6

—

(43055089) Myosin Ab [Presence] in Serum or Plasma by Immunoblot

0.00

0.0

1.0

—

Mortality – FinRegistry

↥

Association

Association between endpoint L12_HYPERTICHNAS and mortality.

Females

No data

Males

No data

Mortality risk

Mortality risk for people of age

years, who have L12_HYPERTICHNAS.

N-year risk	Females	Males
1	No data	No data
5	No data	No data
10	No data	No data
15	No data	No data
20	No data	No data

Relationships between endpoints

↥

Index endpoint: L12_HYPERTICHNAS – Other hypertrichosis

GWS hits: -

Endpoint

Case Overlap

Survival Analysis

Genetic Correlations

Genetic Signals

N (Jaccard index)

HR [CI]

rg [CI]

Hits

Coloc Hits

FinRegistry

FinnGen

FinRegistry

FinnGen

Loading data

Other hypertrichosis

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

1. Apply sex-specific rule

2. Check conditions

3. Check pre-conditions, main-only, mode, registry filters

4. Check minimum number of events

5. Include endpoints

6. Filter based on genotype QC (FinnGen only)

Similar endpoints

Case counts by codes

Summary Statistics

-FinRegistry-

Key figures

-FinnGen-

Key figures

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS (R11)

Matched cohort

LabWAS

Mortality – FinRegistry

Association

Females

Males

Mortality risk

Relationships between endpoints