≡ Risteys
R13

Documentation Changelog GitHub Contact & Feedback

Other congenital malformations of limb(s)

EFO Endpoint Browser PheWeb

Q17_OTHER_CONGEN_MALFO_LIMBS

Endpoint definition

↥

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

519972

1. Apply sex-specific rule

None

519972

2. Check conditions

None

519972

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — Q74
  • Cause of death: ICD-10 — Q74

2 out of 7 registries used, show all original rules.

306

4. Check minimum number of events

None

306

5. Include endpoints

None

306

6. Filter based on genotype QC (FinnGen only)

294

Control definitions (FinnGen only)

Control exclude
Q17_CONGEN_MALFO_DEFORMAT_MUSCULOS_SYSTEM

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF4
Parent code in ICD-10
Q6[5-9]|Q7
Name in latin
Aliae malformationes congenitae membrorum

Similar endpoints

↥

Case counts by codes

↥

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 4390 2208 2179
Only index persons 3749 1902 1847
Unadjusted period prevalence (%)
Whole population 0.06 0.06 0.06
Only index persons 0.07 0.07 0.07
Median age at first event (years)
Whole population 10.78 11.62 9.91
Only index persons 11.95 12.39 11.49

-FinnGen-

Key figures

All Female Male
Number of individuals 294 207 87
Unadjusted period prevalence (%) 0.06 0.07 0.04
Median age at first event (years) 14.50 14.17 15.28

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
306
Matched controls
3060
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
Q74.1
ICD-10 Finland
Congenital malformation of knee
+∞
84.4
77
*
Q74.88
ICD-10 Finland
Other specified congenital malformations of limb(s)
454.4
41.1
40
*
Q74.83
ICD-10 Finland
Congenital limb asymmetri, unspecified
+∞
35.1
33
*
Q74.9
ICD-10 Finland
Unspecified congenital malformation of limb(s)
+∞
28.6
27
*
NFK20
NOMESCO Finland
Epiphysiodesis of femur
147.5
26.0
27
*
Q74.81
ICD-10 Finland
Congenital overgrowth of limb(s)
+∞
25.4
24
*
Q74.01
ICD-10 Finland
Madelung's deformity
+∞
22.1
21
*
Z31.5
ICD-10 Finland
Genetic counselling
5.1
21.2
49
110
NJ2MA
NOMESCO Finland
Measurement of mechanical axis of lower leg with X-ray
8.6
20.3
27
34
Q74.3
ICD-10 Finland
Arthrogryposis multiplex congenita
+∞
18.9
18
*
Q74.80
ICD-10 Finland
Congenital brachydactyli
+∞
17.9
17
*
NGU20
NOMESCO Finland
Removal of internal fixation device from knee or lower leg
15.3
17.2
28
20
Q74.82
ICD-10 Finland
Congenital undergrowth of limb(s)
+∞
16.8
16
*
NGK20
NOMESCO Finland
Epiphysiodesis of knee or lower leg
168.2
15.6
16
*
NFU20
NOMESCO Finland
Removal of internal fixation device from femur
30.4
15.4
20
7
NFK30
NOMESCO Finland
Angulation, rotation or displacement osteotomy of femur
56.0
13.9
16
*
Q74.28
ICD-10 Finland
Other congenital malformations of lower limb(s), including pelvic girdle
+∞
13.6
13
*
ZXE20
NOMESCO Finland
More than three and less than five hours
3.7
13.1
46
141
Q68.8
ICD-10 Finland
Other specified congenital musculoskeletal deformities
+∞
12.6
12
*
ZXE10
NOMESCO Finland
More than one and less than three hours
2.5
12.5
111
568
R4120
NOMESCO Finland
Occupational therapy
4.3
11.8
32
81
Q74.00
ICD-10 Finland
Accessory carpal bones
+∞
11.5
11
*
R4110
NOMESCO Finland
Physiotherapy
2.5
11.4
90
434
ZXD10
NOMESCO Finland
Scheduled procedure
2.3
10.9
114
621
L82
ICPC
Congenital anomaly musculoskeletal
+∞
10.5
10
*
Q66.0
ICD-10 Finland
Talipes equinovarus
+∞
10.5
10
*
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
3.5
9.9
36
112
Z01.0
ICD-10 Finland
Examination of eyes and vision
2.5
9.8
72
333
Z50.9
ICD-10 Finland
Care involving use of rehabilitation procedure, unspecified
7.3
9.5
22
32
SPAT1229
SPAT
Assessment of need for aid
5.4
9.5
19
37
ZXA05
NOMESCO Finland
Left side
2.7
9.5
56
232
WX408
NOMESCO Finland
General anesthesy, balanced
2.3
8.9
86
448
Z3226
NOMESCO Finland
Physiotherapist
2.4
8.8
68
321
M21.0
ICD-10 Finland
Valgus deformity, not elsewhere classified
51.5
8.7
10
*
NGK30
NOMESCO Finland
Angulation, rotation or displacement osteotomy of knee or lower leg
28.4
8.5
11
*
M25.5
ICD-10 Finland
Pain in joint
2.1
8.0
104
605
N02AX02
ATC
tramadol; systemic, rectal
2.1
7.8
91
507
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
3.2
7.8
33
113
NC1AA
NOMESCO Finland
Elbow X-ray examination without contrast
4.5
7.8
19
44
NG1AA
NOMESCO Finland
Knee X-ray examination without contrast
3.1
7.8
34
119
NE1AA
NOMESCO Finland
Pelvis X-ray examination
4.7
7.8
18
40
Q68.1
ICD-10 Finland
Congenital deformity of hand
+∞
7.3
7
*
Q74.02
ICD-10 Finland
Cleidocranial dysostosis
+∞
7.3
7
*
Z46.8
ICD-10 Finland
Fitting and adjustment of other specified devices
8.2
7.2
15
19
ZXA10
NOMESCO Finland
Bilateral
2.4
7.2
56
264
N06AX21
ATC
duloxetine; oral
2.7
7.1
39
155
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
3.1
7.1
30
103
R60.0
ICD-10 Finland
Localized oedema
3.3
7.1
27
87
WX402
NOMESCO Finland
General anaesthesia
2.2
7.0
74
395
NG1BG
NOMESCO Finland
Knee and lower leg MRI examination with high intensity magnet
3.7
7.0
22
62
M21.7
ICD-10 Finland
Unequal limb length (acquired)
14.2
6.9
11
8
ND2AA
NOMESCO Finland
Hand and fingers X-ray examination
2.7
6.9
38
151
R52.2
ICD-10 Finland
Other chronic pain
6.7
6.7
16
25
Q87.88
ICD-10 Finland
Other specified congenital malformation syndromes, not elsewhere classified
23.1
6.7
9
*
M22.1
ICD-10 Finland
Recurrent subluxation of patella
23.1
6.7
9
*
Z3229
NOMESCO Finland
Other healthcare associate professional
2.8
6.6
34
131
Q66.8
ICD-10 Finland
Other congenital deformities of feet
71.3
6.4
7
*
ZXA00
NOMESCO Finland
Right side
2.3
6.4
55
270
Q66.9
ICD-10 Finland
Congenital deformity of feet, unspecified
+∞
6.3
6
*
7558A
ICD-9 Finland
Other congenital anomalies of limbs, Other specified anomalies of unspecified limb[ARTHROGRYPOSIS MULTIPLEX CONGENITA]
+∞
6.3
6
*
Q74.20
ICD-10 Finland
Congenital fusion of sacroiliac joint
+∞
6.3
6
*
TNH36
NOMESCO Finland
Custom molded cast of pes equinovarus
+∞
6.3
6
*
Q74.8
ICD-10 Finland
Other specified congenital malformations of limb(s)
+∞
6.3
6
*
M41.5
ICD-10 Finland
Other secondary scoliosis
+∞
6.3
6
*
9472
FHL
Soft tissue biopsy (muscle, tumor) under general anesthesia or operating room
+∞
6.3
6
*
Q74.2
ICD-10 Finland
Other congenital malformations of lower limb(s), including pelvic girdle
+∞
6.3
6
*
NA7EA
NOMESCO Finland
Scoliosis X-ray examination
7.9
6.2
13
17
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
2.1
6.1
65
347
N03AX16
ATC
[U] pregabalin
2.3
6.1
50
240
N03AX12
ATC
[U] gabapentin; oral
2.6
6.1
38
161

LabWAS

↥
OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
53
236
2.51
7.70
2.5
2.0
—
—
—
0
0
75
395
2.19
7.41
3.9
3.7
—
—
—
0
0
52
250
2.30
6.34
1.9
2.1
392.17
386.27
nmol/l
0.06
47
233
33
134
2.64
5.76
4.9
5.5
81.79
63.80
ng/l
0.28
33
125
91
562
1.88
5.63
3.9
3.1
0.29
0.21
e6/l
0.21
62
412
46
222
2.26
5.55
1.3
1.2
—
—
—
0
0
99
631
1.84
5.53
4.0
3.1
21.14
52.38
e6/l
1.29
74
469
90
579
1.79
4.79
3.9
3.0
—
—
—
0
0
182
1420
1.70
4.78
8.4
9.1
4.10
3.81
e9/l
0.92
158
1239
165
1255
1.68
4.77
7.1
6.6
0.04
0.04
e9/l
0.15
143
1094
50
265
2.06
4.76
1.9
1.5
—
—
—
0
0
165
1256
1.68
4.74
7.1
6.6
0.55
0.53
e9/l
0.62
143
1097
169
1299
1.67
4.65
7.2
7.2
0.19
0.18
e9/l
0.56
151
1161
118
830
1.69
4.53
14.0
7.7
1.21
1.22
mmol/l
1.31
111
775
59
338
1.92
4.51
3.3
2.9
2.34
3.25
e6/l
0.57
28
187
112
783
1.68
4.36
4.8
3.6
74.30
48.40
e6/l
0.42
78
499
169
1324
1.62
4.12
7.0
6.5
2.02
2.14
e9/l
0.58
151
1192
103
723
1.64
3.87
6.6
5.2
35.85
37.71
g/l
2.50
92
686
29
135
2.27
3.81
1.3
1.1
—
—
—
0
0
155
1209
1.57
3.71
7.1
6.8
8.13
7.96
%
0.34
145
1158
80
532
1.68
3.68
3.1
3.2
8.35
8.59
mmol/l
0.14
74
482
149
1157
1.56
3.60
7.2
6.8
0.57
0.65
%
1.44
140
1101
185
1511
1.57
3.56
6.8
5.8
84.43
85.43
u/l
0.09
180
1420
73
478
1.69
3.55
3.9
3.4
7.40
7.40
ph
—
10
75
159
1258
1.55
3.50
6.9
6.4
55.41
53.68
%
1.18
150
1206
151
1185
1.54
3.43
7.4
7.0
—
—
—
0
0
256
2276
1.76
3.36
16.4
9.6
3.90
3.91
mmol/l
0.27
249
2193
160
1277
1.53
3.33
7.0
6.5
30.31
32.23
%
1.59
151
1229
91
640
1.60
3.33
5.7
7.0
—
—
—
0
0
152
1201
1.53
3.31
7.1
6.6
2.90
2.86
%
0.10
142
1146
77
525
1.62
3.18
3.2
3.1
—
—
—
0
0
64
416
1.68
3.18
3.4
2.5
6.29
6.69
e6/l
0.13
53
363
11
30
3.76
3.12
5.4
20.6
74.56
73.51
%
0.06
11
30
154
1234
1.50
3.06
8.9
4.7
6.20
6.24
mmol/l
0.08
140
1093
61
396
1.67
3.04
3.2
2.5
575.81
566.60
mosm/kgh2o
0.08
48
332
123
942
1.51
3.03
4.8
5.5
11.09
12.89
umol/l
0.47
117
890
121
924
1.51
3.02
11.3
7.4
1.21
1.22
mmol/l
1.14
110
806
61
398
1.67
2.98
2.9
3.2
313.06
3900.86
umol/l
1.34
54
363
27
137
2.06
2.90
25.3
7.1
0.01
0.77
mmol/l
0.54
18
106
38
218
1.85
2.89
19.9
8.8
—
—
—
0
0
136
1073
1.48
2.86
2.8
2.5
—
—
—
0
0
86
618
1.54
2.82
3.1
2.3
—
—
—
0
0
10
28
3.66
2.81
3.1
1.1
—
—
—
0
0
40
236
1.80
2.79
2.4
2.5
21.05
24.85
%
0.84
32
213
37
214
1.83
2.75
12.1
7.8
4.96
4.98
kpa
0.05
37
205
37
215
1.82
2.71
1.5
1.3
—
—
—
0
0
48
302
1.70
2.68
1.8
1.5
400.62
25188406.36
pmol/l
0.50
37
266
38
224
1.80
2.66
1.2
1.3
—
—
—
0
0
40
242
1.75
2.57
7.0
8.6
1.49
1.23
mmol/l
0.28
35
190
86
630
1.51
2.55
1.7
1.6
97.44
98.67
pmol/l
0.08
41
330
6
11
5.54
2.55
1.2
1.6
7.45
9.83
u/l
—
6
11
38
227
1.77
2.55
1.3
1.2
—
—
—
0
0
24
123
2.03
2.53
28.2
7.5
96.19
96.10
%
0.03
24
115
15
63
2.45
2.50
35.7
9.6
22.80
24.13
mmol/l
0.80
15
63
9
26
3.53
2.50
3.3
3.8
20.56
27.42
%
—
9
26
9
27
3.40
2.41
3.3
4.1
25.00
13.19
%
—
9
27
64
445
1.55
2.40
2.6
3.0
123.35
82.72
ug/g
0.50
56
345
13
52
2.57
2.39
2.8
2.0
—
—
—
0
0
188
1614
1.43
2.36
4.7
3.8
—
—
—
0
0
42
265
1.68
2.33
2.4
2.3
2.45
2.41
mmol/l
1.48
32
226
13
53
2.52
2.31
2.0
2.6
—
—
—
0
0
5
9
5.63
2.22
2.0
1.4
77.40
50.33
nmol/l
—
5
9
36
221
1.71
2.21
7.4
8.8
5.34
5.10
kpa
0.26
36
215
16
74
2.23
2.19
5.0
11.4
0.69
0.65
%
0.19
16
74
21
109
1.99
2.16
31.9
7.6
121.95
123.71
g/l
0.13
21
103
17
82
2.14
2.11
2.0
1.6
—
—
—
0
0
252
2306
1.53
2.11
18.3
12.4
14.16
13.86
%
0.45
245
2275
9
31
2.96
2.09
2.2
4.5
—
—
—
0
0
30
178
1.76
2.08
9.6
9.4
105.03
104.67
mmol/l
0.20
30
178
28
164
1.78
2.03
14.0
8.5
9.95
9.75
kpa
0.32
28
159
24
134
1.86
2.02
1.4
1.2
—
—
—
0
0
140
1168
1.37
1.95
10.5
8.5
0.00
0.00
e9/l
-0.00
114
935
5
11
4.60
1.95
2.8
1.8
—
—
—
0
0
65
475
1.47
1.93
3.2
2.6
1.30
0.79
mg/l
0.67
50
335
196
1727
1.38
1.91
4.6
3.7
37.34
37.19
mmol/mol
0.07
187
1634
29
175
1.73
1.91
1.5
1.8
13.87
14.93
iu/l
0.08
21
134
31
192
1.68
1.86
1.4
1.4
—
—
—
0
0
78
594
1.42
1.86
2.4
2.6
2.38
2.36
mmol/l
0.37
69
541
67
496
1.45
1.86
1.4
1.7
1.49
1.35
mmol/l
0.37
59
443
7
23
3.09
1.81
2.0
2.1
1.21
1.73
mmol/l
—
7
23
29
178
1.70
1.80
14.1
8.1
24.27
24.09
mmol/l
0.18
29
178
48
334
1.52
1.80
4.2
4.2
2.75
16.52
mg/mmol
2.98
35
228
8
29
2.80
1.80
3.1
3.2
38.88
37.08
%
—
8
29
22
126
1.80
1.73
2.9
2.2
—
—
—
0
0
8
31
2.62
1.67
1.8
1.3
—
—
—
0
0
15
77
2.00
1.62
2.1
2.4
—
—
—
0
0
52
377
1.46
1.61
1.5
1.4
20.69
19.56
nmol/l
0.21
47
327
8
33
2.46
1.55
7.0
19.3
—
—
—
0
0
5
15
3.37
1.53
2.2
2.1
33303.00
36586.67
ug/l
—
5
15
6
21
2.89
1.51
3.8
1.2
—
—
nmol/l
—
0
0
45
322
1.47
1.49
3.3
3.6
1338.92
113.76
mg/l
0.46
34
221
43
305
1.48
1.49
2.8
2.5
8116.26
3053.49
u/l
0.40
18
135
37
255
1.51
1.47
3.8
4.2
5.72
8.98
umol/l
0.91
29
211
6
22
2.76
1.44
2.7
2.4
—
—
—
0
0
211
1921
1.32
1.42
4.4
3.9
14.37
14.43
pmol/l
0.13
199
1772
274
2600
1.51
1.42
12.9
8.2
—
—
—
0
0
134
1153
1.29
1.38
3.4
3.0
0.00
0.00
estimate
-0.00
21
244
115
971
1.30
1.37
2.8
2.9
6.26
5.89
ph
1.28
17
90
185
1661
1.29
1.35
5.2
3.7
10.13
8.31
mm/h
1.19
174
1549
27
177
1.58
1.34
15.7
8.2
—
—
—
0
0
25
161
1.60
1.33
2.7
1.8
1.02
1.12
g/l
0.36
25
148
32
219
1.52
1.32
1.6
1.5
—
—
—
0
0
239
2224
1.34
1.32
5.0
4.4
1.79
2.32
mu/l
0.50
225
2096
80
646
1.32
1.31
8.9
7.7
1.12
1.11
inr
0.03
25
216
6
24
2.53
1.31
3.7
1.3
—
—
—
0
0
13
69
1.92
1.30
11.1
3.7
—
—
—
0
0
10
48
2.12
1.29
1.7
1.7
—
—
—
0
0
134
1163
1.27
1.26
3.5
3.1
0.00
0.00
estimate
-0.00
17
228
25
164
1.57
1.25
1.5
1.9
5.50
7.70
u/l
1.02
16
123
263
2490
1.40
1.24
9.9
7.7
29.74
25.25
u/l
1.84
255
2409
66
523
1.33
1.23
3.1
3.0
1.02
1.02
kg/l
—
8
73
82
671
1.30
1.22
2.7
2.2
—
—
—
0
0
5
19
2.66
1.22
10.0
30.3
12.48
11.34
%
—
5
19
5
19
2.66
1.22
2.0
1.7
91.58
92.74
%
—
5
19
23
149
1.59
1.21
1.6
2.1
11.77
12.01
nmol/l
0.03
18
134
16
94
1.74
1.20
3.1
2.6
0.22
0.15
e6/l
0.28
16
88
94
786
1.28
1.18
1.7
1.8
—
—
—
0
0
25
167
1.54
1.16
1.6
1.3
—
—
—
0
0
39
287
1.41
1.14
4.2
2.6
303.32
465.07
ng/l
0.30
25
150
18
112
1.65
1.11
4.8
2.9
1.22
1.23
mmol/l
0.37
13
93
56
441
1.33
1.09
1.7
1.6
—
—
—
0
0
13
74
1.79
1.08
49.7
7.7
—
—
—
0
0
92
779
1.26
1.04
1.8
1.5
2.19
1.90
g/l
0.63
56
452
140
1244
1.23
1.02
3.1
2.6
—
—
—
0
0
130
1149
1.23
0.99
4.7
4.4
0.00
0.00
estimate
-0.00
21
239
0
29
0.00
0.98
0.0
1.1
—
—
—
0
0
49
385
1.32
0.98
1.3
1.3
10.62
23.32
iu/ml
—
10
114
293
2852
1.64
0.96
22.1
14.4
40.58
40.15
%
0.93
279
2726
28
202
1.43
0.93
1.5
1.4
254.54
310.94
mu/l
1.01
28
182
70
586
1.25
0.87
2.6
2.6
2.75
2.66
mg/l
0.14
63
507
27
197
1.41
0.85
6.6
2.8
10.49
9.68
g/l
0.47
27
180
6
31
1.95
0.85
7.8
2.9
—
—
—
0
0
71
598
1.24
0.84
3.5
3.1
0.00
0.00
estimate
0.50
19
237
14
90
1.58
0.79
1.0
1.1
—
—
—
0
0
24
174
1.41
0.79
3.1
4.7
0.22
0.22
g/l
0.00
24
166
8
48
1.68
0.79
2.4
4.3
3.35
9.27
u/ml
—
8
48
0
26
0.00
0.79
0.0
1.1
—
—
—
0
0
292
2851
1.53
0.79
20.7
14.3
269.11
261.61
e9/l
1.14
286
2768
62
521
1.24
0.75
2.8
2.4
20.01
26.10
ng/l
0.31
27
212
5
25
2.02
0.73
5.4
5.0
1.60
2.60
ug/l
—
5
25
5
25
2.02
0.73
1.6
1.2
—
—
—
0
0
10
60
1.69
0.73
1.6
1.2
—
—
—
0
0
292
2856
1.49
0.71
20.6
14.3
4.61
4.56
e12/l
0.88
286
2775
14
93
1.53
0.70
2.6
1.6
0.19
0.23
g/l
0.92
14
87
259
2497
1.24
0.67
15.2
9.5
22.59
20.11
mg/l
0.50
198
1816
210
1987
1.18
0.66
3.7
3.0
5.65
5.54
mmol/l
0.52
191
1840
292
2860
1.46
0.65
20.7
14.3
7.13
6.74
e9/l
2.32
286
2775
5
29
1.74
0.64
1.2
1.2
—
—
—
0
0
5
29
1.74
0.64
1.0
1.2
0.45
1.45
u/ml
—
5
21
97
868
1.17
0.61
1.7
1.5
0.64
2.12
u/ml
1.80
20
205
26
331
0.77
0.61
1.3
1.3
—
—
—
0
0
8
51
1.58
0.61
1.1
1.7
—
—
—
0
0
15
208
0.71
0.60
1.5
1.3
—
—
—
0
0
14
97
1.46
0.60
2.6
1.5
1.14
1.19
g/l
0.42
14
90
33
267
1.26
0.57
1.6
1.5
—
—
—
0
0
46
387
1.22
0.57
1.2
1.2
3.19
8.84
u/ml
1.23
14
153
8
55
1.47
0.56
4.8
5.9
—
—
—
0
0
13
90
1.46
0.56
1.6
1.7
—
—
—
0
0
12
82
1.48
0.55
1.3
1.4
—
—
—
0
0
7
48
1.47
0.47
1.0
1.1
—
—
—
0
0
63
709
0.86
0.47
1.7
1.8
—
—
—
0
0
101
925
1.14
0.46
1.7
1.8
—
—
—
0
0
9
130
0.68
0.44
5.1
3.0
—
—
—
0
0
13
172
0.74
0.42
1.1
1.1
—
—
—
0
0
0
15
0.00
0.41
0.0
1.1
—
—
—
0
0
0
16
0.00
0.41
0.0
1.1
—
—
—
0
0
0
17
0.00
0.41
0.0
1.0
—
—
—
0
0
0
17
0.00
0.41
0.0
1.1
—
—
—
0
0
211
2031
1.13
0.40
3.9
3.3
2.94
2.81
mmol/l
1.22
199
1920
10
72
1.40
0.37
1.1
1.1
1.53
8.94
u/ml
—
5
36
11
82
1.35
0.34
3.7
2.8
147.47
113.79
ng/l
0.10
11
76
6
45
1.34
0.34
2.0
1.4
—
—
—
0
0
35
304
1.17
0.33
2.4
2.0
—
—
—
0
0
167
1603
1.09
0.30
3.3
3.1
41.51
31.15
u/l
0.84
158
1544
36
317
1.15
0.30
1.4
1.2
—
—
—
0
0
17
139
1.24
0.29
1.6
2.4
—
—
—
0
0
7
56
1.26
0.29
4.4
2.0
1.05
0.69
nmol/l
—
7
47
8
64
1.26
0.27
1.6
3.0
—
—
—
0
0
8
65
1.24
0.27
1.3
1.1
—
—
—
0
0
209
2033
1.09
0.26
3.7
3.2
4.70
4.64
mmol/l
0.33
198
1934
9
73
1.24
0.25
1.1
1.1
—
—
—
0
0
9
73
1.24
0.25
1.1
1.1
—
—
—
0
0
76
812
0.91
0.25
2.7
2.0
—
—
—
0
0
6
82
0.73
0.24
1.0
1.3
—
—
—
0
0
6
82
0.73
0.24
1.2
1.2
—
—
—
0
0
5
39
1.29
0.23
1.8
1.6
—
—
—
0
0
5
39
1.29
0.23
1.0
1.3
0.91
2.54
u/ml
—
5
21
56
604
0.91
0.22
1.7
1.6
—
—
—
0
0
5
42
1.19
0.21
1.0
3.4
4.01
3.52
e9/l
—
5
42
0
10
0.00
0.21
0.0
1.0
—
5.33
—
0
10
0
10
0.00
0.21
0.0
1.2
—
—
—
0
0
0
10
0.00
0.21
0.0
6.0
—
—
—
0
0
15
126
1.20
0.21
1.5
1.5
—
—
—
0
0
0
12
0.00
0.21
0.0
1.2
—
—
—
0
0
5
43
1.17
0.21
1.0
3.5
59.20
54.19
%
—
5
43
5
43
1.17
0.21
1.0
1.0
—
—
—
0
0
14
117
1.21
0.21
3.3
3.6
5.68
9.75
umol/l
—
9
88
206
2014
1.07
0.19
3.5
3.1
1.39
1.48
mmol/l
2.57
196
1907
14
118
1.20
0.19
1.1
1.4
—
—
—
0
0
27
242
1.13
0.19
1.3
1.3
65.16
142.95
iu/ml
—
10
91
12
100
1.21
0.18
1.2
1.2
—
—
—
0
0
7
63
1.11
0.17
2.1
1.8
—
—
—
0
0
18
158
1.15
0.16
1.5
1.5
—
—
—
0
0
8
69
1.16
0.16
6.9
7.7
—
—
—
0
0
97
1009
0.94
0.16
2.3
2.2
—
—
—
0
0
9
81
1.11
0.15
1.6
1.1
—
—
—
0
0
42
392
1.08
0.15
3.0
2.8
—
—
—
0
0
16
179
0.89
0.12
1.3
1.5
—
—
—
0
0
28
301
0.92
0.11
1.4
1.9
—
—
—
0
0
28
300
0.93
0.10
1.4
1.9
—
—
—
0
0
5
45
1.11
0.10
27.2
4.8
2.12
1.61
%
—
5
38
5
48
1.04
0.09
2.2
1.3
—
—
—
0
0
70
677
1.04
0.09
2.8
2.6
—
—
—
0
0
10
88
1.14
0.08
1.1
1.1
0.17
5.52
u/ml
—
5
51
8
78
1.03
0.07
3.5
2.2
—
—
—
0
0
16
173
0.92
0.07
1.3
1.4
—
—
—
0
0
16
173
0.92
0.07
1.3
1.4
—
—
—
0
0
194
1922
1.03
0.05
3.3
2.9
1.30
1.17
mmol/l
1.46
183
1817
29
303
0.95
0.05
1.4
1.9
—
—
—
0
0
13
120
1.09
0.05
1.1
1.1
4.13
5.47
u/ml
—
7
87
29
302
0.96
0.04
1.4
1.9
—
—
—
0
0
22
209
1.06
0.04
1.2
2.5
—
—
—
0
0
13
140
0.93
0.04
3.7
3.4
49.48
66.87
e9/l
—
8
96
22
211
1.05
0.03
4.4
3.0
—
—
—
0
0
27
279
0.96
0.02
1.4
2.0
—
—
—
0
0
11
117
0.94
0.02
1.1
1.1
0.07
1.37
u/ml
—
5
74
24
234
1.03
0.00
1.2
2.1
—
—
—
0
0
10
99
1.01
0.00
2.2
1.5
—
—
—
0
0
14
137
1.02
0.00
2.8
3.8
—
—
—
0
0
79
793
0.99
0.00
1.9
1.8
—
—
—
0
0
8
79
1.01
0.00
1.5
2.6
1.50
6.92
e6/l
—
8
60
0
5
0.00
0.00
0.0
13.6
—
—
—
0
0
0
5
0.00
0.00
0.0
14.8
—
—
—
0
0
8
79
1.01
0.00
1.5
2.7
67.50
103.83
e6/l
—
8
64
7
69
1.01
0.00
1.4
1.2
—
—
—
0
0
0
7
0.00
-0.00
0.0
7.0
—
49.50
—
0
7
6
65
0.92
-0.00
1.7
1.6
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
9
0.00
-0.00
0.0
26.0
—
0.61
—
0
9
0
8
0.00
-0.00
0.0
1.4
—
54.00
—
0
8
0
6
0.00
-0.00
0.0
1.5
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
5
54
0.92
-0.00
4.4
2.6
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
9.17
—
0
6

Mortality – FinRegistry

↥

Association

Association between endpoint Q17_OTHER_CONGEN_MALFO_LIMBS and mortality.

Females

No data

Males

No data

Mortality risk

Mortality risk for people of age

years, who have Q17_OTHER_CONGEN_MALFO_LIMBS.

N-year risk Females Males
1 No data No data
5 No data No data
10 No data No data
15 No data No data
20 No data No data

Relationships between endpoints

↥

Index endpoint: Q17_OTHER_CONGEN_MALFO_LIMBS – Other congenital malformations of limb(s)

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
loading spinner Loading data