Crushing injury of head

ST19_CRUSHI_INJURY_HEAD

No definition available.

Endpoint definition

↥

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps	FinnGen
Phenotype data	519972
1. Apply sex-specific rule None	519972
2. Check conditions None	519972
3. Check pre-conditions, main-only, mode, registry filters Registry filters: Hospital discharge: ICD-10 — S07 Cause of death: ICD-10 — S07 2 out of 7 registries used, show all original rules.	52
4. Check minimum number of events None	52
5. Include endpoints None	52
6. Filter based on genotype QC (FinnGen only)	52

Control definitions (FinnGen only)

Control exclude: ST19_INJURI_HEAD

Extra metadata

Level in the ICD hierarchy: 3
First used in FinnGen datafreeze: DF4
Parent code in ICD-10: S0
Name in latin: Conquassatio capitis

NAME	ST19_CRUSHI_INJURY_HEAD
CONTROL_EXCLUDE	ST19_INJURI_HEAD
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX
INCLUDE
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10	S07
HD_ICD_9
HD_ICD_8
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10	S07
COD_ICD_9
COD_ICD_8
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

Similar endpoints

↥

List of similar endpoints to Crushing injury of head based on the number of shared cases.

Similar with more cases:

Similar with less cases:

None

Case counts by codes

↥

FinnGen case counts by registry codes:

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

	All	Female	Male
Number of individuals	52	24	28
Unadjusted period prevalence (%)	0.01	0.01	0.01
Median age at first event (years)	50.08	52.17	48.30

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log₁₀(p-value) ≥ 6.

Matched cohort

Matched cases
52: Matched controls
520

Code

Vocabulary

Description

Odds Ratio

-log₁₀(p)

N matched cases

N matched controls

S07.0

ICD-10 Finland

Crushing injury of face

+∞

42.7

S06.0

ICD-10 Finland

Concussion

44.9

13.5

S02.70

ICD-10 Finland

Multiple fractures involving skull and facial bones, closed

+∞

10.8

AA1AD

NOMESCO Finland

CT of head and brain

5.1

7.5

S07.1

ICD-10 Finland

Crushing injury of skull

+∞

7.5

EFB40

NOMESCO Finland

Removal of internal or external fixation device from facial bones

+∞

7.5

WX408

NOMESCO Finland

General anesthesy, balanced

4.8

6.9

W01

ICD-10 Finland

Fall on same level from slipping, tripping and stumbling

4.6

6.8

CAC10

NOMESCO Finland

Reconstruction of orbital wall using bone graft or plate

+∞

6.4

S07.8

ICD-10 Finland

Crushing injury of other parts of head

+∞

6.4

S01.0

ICD-10 Finland

Open wound of scalp

17.7

6.2

LabWAS

↥

N Cases

N Controls

-log₁₀(p)

cases

controls

cases

controls

unit

-log₁₀(p)

N cases

N controls

(3005785) Creatine kinase.MB [Mass/volume] in Serum or Plasma

3.40

2.78

2.1

3.1

8.85

5.56

ug/l

0.45

(3019309) Folate [Moles/volume] in Red Blood Cells

2.94

2.77

1.9

1.6

1369.05

1245.59

nmol/l

0.20

(3014162) Mycobacterium tuberculosis DNA [Presence] in Specimen by NAA with probe detection

6.00

2.62

4.2

1.9

—

(3019060) Gas panel - Arterial blood

3.50

2.52

4.7

18.0

—

(46236098) ABO and Rh group [Type] in Blood by Confirmatory method

2.58

2.52

2.3

2.9

—

(3029287) Urinalysis microscopic panel [#/volume] - Urine by Automated count

145

2.39

2.40

3.2

3.1

—

(3044640) Blood type and Crossmatch panel - Blood

121

2.42

2.37

2.9

2.6

—

(3022217) INR in Platelet poor plasma by Coagulation assay

181

2.36

2.34

24.7

12.7

1.16

1.17

inr

—

(3023368) Bacteria identified in Blood by Culture

107

2.41

2.27

4.0

4.2

—

(3013826) Glucose [Moles/volume] in Serum or Plasma

240

2.40

2.25

5.7

7.0

6.65

6.85

mmol/l

0.18

227

(3004119) Hemoglobin [Mass/volume] in Venous blood

3.31

2.03

1.6

3.8

122.50

121.96

g/l

—

(43054903) Holo-transcobalamin II [Moles/volume] in Serum

156

2.16

1.93

3.3

1.7

87.67

94.36

pmol/l

0.28

(3014111) Lactate [Moles/volume] in Serum or Plasma

2.89

1.91

1.6

7.8

1.37

1.36

mmol/l

—

(3020779) Urea [Moles/volume] in Serum or Plasma

2.96

1.81

1.9

15.0

7.71

9.85

mmol/l

—

(3000991) Gas panel - Venous blood

2.86

1.74

2.5

11.4

—

(3001079) Blood group antibody screen [Presence] in Serum or Plasma

179

2.06

1.73

2.8

3.0

—

(3024889) Methemoglobin/Hemoglobin.total in Venous blood

3.07

1.72

1.7

2.5

0.47

0.81

—

(3020891) Body temperature

2.95

1.64

7.3

4.8

—

(3010517) Carboxyhemoglobin/Hemoglobin.total in Venous blood

2.95

1.64

1.7

2.4

1.47

1.28

—

(3043924) Respiratory syncytial virus RNA [Identifier] in Specimen by NAA with probe detection

2.58

1.52

1.7

—

(3038288) Influenza virus B RNA [Presence] in Specimen by NAA with probe detection

2.58

1.52

1.8

1.9

—

(3017143) Hepatitis C virus Ab [Presence] in Serum

2.36

1.51

1.0

1.6

—

(3007628) Bicarbonate [Moles/volume] standard in Venous blood

3.14

1.39

2.2

7.1

25.20

23.76

mmol/l

—

(3017895) Helicobacter pylori Ab [Units/volume] in Serum

3.14

1.39

1.4

1.5

—

(36304419) Bacteria [Presence] in Urine

104

1.94

1.30

3.8

3.0

—

(3037467) Urinalysis macro (dipstick) panel - Urine

271

1.89

1.29

3.7

4.2

—

(3019902) Methicillin resistant Staphylococcus aureus [Presence] in Specimen by Organism specific culture

2.37

1.28

3.4

2.9

—

(3019800) Troponin T.cardiac [Mass/volume] in Serum or Plasma

149

1.83

1.23

4.4

4.0

24.69

32.93

ng/l

0.52

107

(3002032) Base excess in Venous blood by calculation

2.18

1.18

2.5

5.1

3.30

1.86

mmol/l

—

(3021447) Carbon dioxide [Partial pressure] in Venous blood

2.18

1.18

2.5

5.1

6.49

5.89

kpa

—

(3004716) Salmonella sp identified in Stool by Organism specific culture

2.52

1.11

1.0

1.1

—

(586526) SARS-CoV-2 (COVID-19) RNA [Presence] in Nasopharynx by NAA with probe detection

2.52

1.11

1.0

1.1

—

(3018095) Leukocytes [#/volume] in Urine

144

1.77

1.11

3.4

3.5

13.34

39.61

e6/l

1.12

100

(40768797) Stomach Pathology biopsy report

2.10

1.09

1.6

1.2

—

(3026008) Bacteria identified in Urine by Culture

111

1.79

1.05

3.4

3.3

—

(3024354) Oxygen [Partial pressure] in Venous blood

2.15

1.04

2.3

5.3

3.21

4.39

kpa

—

(3045783) Sodium and Potassium panel [Moles/volume] - Serum or Plasma

2.01

1.00

7.7

9.3

—

(3022621) pH of Urine by Test strip

2.29

0.95

2.8

1.9

—

(3025941) Bacteria identified in Stool by Culture

2.29

0.95

1.5

1.1

—

(3022250) Lactate dehydrogenase [Enzymatic activity/volume] in Serum or Plasma by Lactate to pyruvate reaction

2.07

0.94

1.8

4.8

258.00

247.31

u/l

—

(3042936) Bacteria identified in Isolate by Culture

2.01

0.92

2.4

3.3

—

(3020059) Calcium [Moles/volume] corrected for albumin in Serum or Plasma

1.88

0.91

2.8

2.43

2.45

mmol/l

0.45

(3000067) Parathyrin.intact [Mass/volume] in Serum or Plasma

2.13

0.90

1.2

3.7

80.50

71.86

ng/l

—

(40760892) CBC W Ordered Manual Differential panel - Blood

189

1.62

0.89

7.2

—

(3019050) Tissue transglutaminase IgA Ab [Units/volume] in Serum

1.72

0.88

1.2

1.3

0.66

1.04

u/ml

—

(3014007) Fractional oxyhemoglobin in Arterial blood

1.99

0.85

7.2

9.3

94.28

94.60

—

(40758558) Short blood count panel - Blood

103

1.64

0.76

4.3

7.2

—

(3001308) Cholesterol in LDL [Moles/volume] in Serum or Plasma

409

1.74

0.68

4.8

4.6

2.58

2.73

mmol/l

0.55

376

(46235355) HIV 1 and 2 tests - Meaningful Use set

1.65

0.67

1.3

1.6

—

(3033658) Prothrombin time (PT) actual/Normal

1.61

0.66

6.9

3.3

87.38

89.01

0.06

(40761536) Microorganisms panel - Urine sediment

1.80

0.65

5.0

3.3

—

(3021879) Hepatitis B virus core Ab [Presence] in Serum

1.74

0.63

1.0

1.7

—

(40764999) Glomerular filtration rate/1.73 sq M.predicted [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (CKD-EPI)

377

1.59

0.58

15.2

12.1

82.77

82.73

ml/min/173m2

0.00

304

(3044938) Influenza virus A RNA [Presence] in Specimen by NAA with probe detection

1.57

0.58

1.9

—

(3002256) Pathology report gross observation

1.70

0.58

1.2

1.1

—

(3019284) Hepatitis B virus surface Ag [Presence] in Serum

1.64

0.57

1.1

1.6

—

(3015377) Calcium [Moles/volume] in Serum or Plasma

128

1.49

0.57

1.9

3.7

2.33

2.36

mmol/l

0.83

115

(3019832) Treponema pallidum Ab [Presence] in Serum

1.65

0.56

1.0

1.4

—

(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection

274

1.44

0.55

3.6

3.3

—

(21494755) Public health laboratory ask at order entry panel

1.53

0.49

1.3

1.2

—

(3003510) Neisseria gonorrhoeae DNA [Presence] in Urine by NAA with probe detection

1.49

0.48

1.4

1.9

—

(3007853) Bacteria identified in Skin by Aerobe culture

1.49

0.48

4.1

1.5

—

(3020682) Albumin/Creatinine [Ratio] in Urine

114

1.44

0.48

2.8

3.5

1.55

12.26

mg/mmol

—

(3009261) Glucose [Presence] in Urine by Test strip

199

1.38

0.47

3.6

4.3

0.00

estimate

—

(40768804) Tissue Pathology biopsy report

144

1.38

0.43

2.8

1.7

—

(3050129) First trimester maternal screen panel - Serum or Plasma

0.00

0.42

0.0

1.1

—

(36031861) Influenza virus A and B and SARS-CoV-2 (COVID-19) and Respiratory syncytial virus RNA panel - Respiratory system specimen by NAA with probe detection

0.00

0.41

0.0

1.4

—

(3023602) Cholesterol in HDL [Moles/volume] in Serum or Plasma

399

1.45

0.41

4.5

4.2

1.40

1.45

mmol/l

0.35

366

(3012516) Albumin [Mass/volume] in Urine

109

1.39

0.39

2.9

3.1

11.03

79.91

mg/l

—

(40761535) Cells panel - Urine sediment

1.38

0.35

1.8

4.2

—

(3029937) Albumin [Presence] in Urine by Test strip

102

1.37

0.34

5.0

4.4

0.00

estimate

—

(3024950) Chlamydia trachomatis DNA [Presence] in Urine by NAA with probe detection

1.37

0.32

1.7

2.0

—

(3021601) Nitrite [Presence] in Urine by Test strip

199

1.28

0.31

4.0

5.8

0.00

estimate

—

(3001784) Prostate Specific Ag Free/Prostate specific Ag.total in Serum or Plasma

105

1.32

0.28

5.8

4.1

21.17

21.78

—

(3024135) Streptococcus.beta-hemolytic [Presence] in Throat by Organism specific culture

0.65

0.28

1.6

1.5

—

(3044889) 12 lead EKG panel

262

1.24

0.26

5.2

3.8

—

(40763086) Leukocyte esterase [Presence] in Urine by Automated test strip

145

1.26

0.25

4.3

4.6

—

(3000494) Fungus identified in Specimen by Culture

1.21

0.22

3.8

1.9

—

(3003191) Choriogonadotropin (pregnancy test) [Presence] in Serum or Plasma

0.00

0.21

0.0

1.2

—

(36033641) SARS-CoV-2 (COVID-19) Ag [Presence] in Upper respiratory specimen by Rapid immunoassay

0.00

0.21

0.0

1.4

—

(3043109) Cytology report of Tissue fine needle aspirate Cyto stain

0.00

0.21

0.0

1.2

—

(3018006) Microscopic observation [Identifier] in Cervix by Cyto stain.thin prep

1.28

0.21

1.7

1.3

—

(3002434) Lupus erythematosus deoxynucleoproteins IgG Ab [Units/volume] in Serum by Immunoassay

0.00

0.20

0.0

1.4

—

(1761482) Bacteria [#/volume] in Urine by Culture

0.00

0.20

0.0

7.1

—

(3013512) EKG study

110

1.24

0.19

3.5

3.8

—

(3035350) Ketones [Presence] in Urine by Test strip

199

1.18

0.17

3.6

4.3

0.00

estimate

—

(3018251) Fasting glucose [Moles/volume] in Serum or Plasma

391

1.23

0.17

4.7

4.4

5.79

5.88

mmol/l

0.26

353

(3041096) Erythrocytes [Presence] in Urine by Automated

102

1.10

0.03

3.8

3.5

—

(3048773) Triglyceride [Moles/volume] in Serum or Plasma --fasting

382

1.08

0.03

5.2

4.0

1.13

1.31

mmol/l

0.78

349

(1761868) Lipid panel - Serum or Plasma

143

1.07

0.02

3.2

2.6

—

(3011397) Hemoglobin [Presence] in Urine by Test strip

101

0.99

0.00

3.8

4.4

—

(3003694) ABO and Rh group [Type] in Blood

116

1.04

0.00

1.2

1.4

—

(3032155) Metanephrine Free [Moles/volume] in Serum or Plasma

0.00

0.0

1.2

—

(4094501) Cardiovascular stress test using bicycle ergometer

0.00

0.0

1.0

—

(3028707) Methadone [Presence] in Urine by Screen method

0.00

0.0

1.6

—

(3025023) Rhinovirus RNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

2.0

—

(3041642) Human coronavirus 229E RNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

2.1

—

(3037756) Immunofixation for Serum or Plasma

0.00

0.0

1.1

—

(3040359) Human coronavirus NL63 RNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

2.1

—

(40768795) Lymph node Pathology biopsy report

0.00

0.0

1.2

—

(3023420) DNA double strand Ab [Units/volume] in Serum

0.00

0.0

1.2

—

(3023511) Choriogonadotropin [Units/volume] in Urine

0.00

0.0

2.3

—

(3038546) Human coronavirus OC43 RNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

2.1

—

(3027544) Mycobacterium sp identified in Sputum by Organism specific culture

0.00

0.0

3.0

—

(40758310) Human epididymis protein 4 [Moles/volume] in Serum or Plasma

0.00

0.0

1.3

—

77.17

—

(40768793) Breast Pathology biopsy report

0.00

0.0

1.3

—

(3027456) Digoxin [Moles/volume] in Serum or Plasma

0.00

0.0

3.2

—

0.77

—

(3025468) Yersinia sp identified in Specimen by Organism specific culture

0.00

0.0

1.7

—

(3016701) Glucose [Moles/volume] in Serum or Plasma --2 hours post dose glucose

0.00

0.0

1.4

—

7.56

—

(3050238) Crystals [Presence] in Synovial fluid by Light microscopy

0.00

0.0

1.1

—

(3025130) Human papilloma virus identified in Specimen

0.00

0.0

2.7

—

(3035285) Chloride [Moles/volume] in Venous blood

0.00

-0.00

0.0

2.5

—

108.25

—

(3012568) Campylobacter sp identified in Specimen by Organism specific culture

0.00

-0.00

0.0

1.6

—

(4146454) Self-monitoring of blood glucose

0.00

-0.00

0.0

1.8

—

(3045142) Bone marrow Pathology biopsy report

0.00

-0.00

0.0

1.2

—

(40763531) Fetal Nuchal fold [Multiple of the median] Thickness adjusted for maternal weight

0.00

-0.00

0.0

1.1

—

(3005988) Vibrio sp identified in Specimen by Organism specific culture

0.00

-0.00

0.0

1.6

—

(3009340) Metanephrine [Moles/volume] in Serum or Plasma

0.00

-0.00

0.0

1.2

—

(46235831) Pregnancy associated plasma protein A [Multiple of the median] adjusted in Serum or Plasma

0.00

-0.00

0.0

1.1

—

(3039443) Prostate specific Ag panel - Serum or Plasma

0.00

-0.00

0.0

1.8

—

(3024522) Salmonella sp identified in Specimen by Organism specific culture

0.00

-0.00

0.0

1.6

—

(3000012) Reticulocyte production index

0.00

-0.00

0.0

2.0

—

(42868716) Shigella species+EIEC invasion plasmid antigen H ipaH gene [Presence] in Stool by NAA with probe detection

0.00

-0.00

0.0

1.6

—

(36305771) Cryptosporidium sp DNA [Presence] in Stool by NAA with probe detection

0.00

-0.00

0.0

1.0

—

(40759040) C peptide [Moles/volume] in Serum or Plasma --post meal

0.00

-0.00

0.0

1.2

—

1.44

—

(3049539) Genetic diseases [Identifier] in Blood or Tissue by FISH Nominal

0.00

-0.00

0.0

1.2

—

(3049207) Fetal Trisomy 21 risk [Likelihood] Based on maternal age

0.00

-0.00

0.0

1.1

—

(3038515) Glucose [Moles/volume] in Venous blood

0.00

-0.00

0.0

4.1

—

5.88

—

(3035320) C reactive protein [Mass/volume] in Body fluid

0.00

-0.00

0.0

1.6

—

(3030408) 3-Methoxytyramine [Moles/volume] in Serum or Plasma

0.00

-0.00

0.0

1.2

—

(3005033) Fetal Nuchal fold Thickness US

0.00

-0.00

0.0

1.1

—

(3008037) Lactate [Moles/volume] in Venous blood

0.00

-0.00

0.0

4.1

—

1.32

—

(3041354) Potassium [Moles/volume] in Venous blood

0.00

-0.00

0.0

2.5

—

3.92

—

(3027953) Aldolase [Enzymatic activity/volume] in Serum or Plasma

0.00

-0.00

0.0

1.2

—

4.80

—

(3016881) Enterovirus RNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

1.7

—

(3012202) Varicella zoster virus DNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

1.4

—

(21493466) Plesiomonas shigelloides DNA [Presence] in Stool by NAA with non-probe detection

0.00

-0.00

0.0

1.6

—

(3050380) Cytology report of Cervical or vaginal smear or scraping Cyto stain

0.00

-0.00

0.0

1.0

—

(3026389) Candida sp identified in Specimen by Organism specific culture

0.00

-0.00

0.0

1.0

—

(3043238) Trisomy 21 risk [Likelihood] in Fetus

0.00

-0.00

0.0

1.4

—

(3019420) Tryptase [Mass/volume] in Serum or Plasma

0.00

-0.00

0.0

1.6

—

7.90

—

(3033705) Calcium.ionized [Moles/volume] in Venous blood

0.00

-0.00

0.0

2.5

—

(3047352) Trisomy 18 risk [Likelihood] in Fetus

0.00

-0.00

0.0

1.1

—

(3013527) Hepatitis B virus core IgM Ab [Presence] in Serum

0.00

-0.00

0.0

1.3

—

(36305247) Microscopic observation [Identifier] in Isolate by Gram stain

0.00

-0.00

0.0

1.8

—

(3008714) Choriogonadotropin [Multiple of the median] adjusted in Serum or Plasma

0.00

-0.00

0.0

1.1

—

(37020937) Giardia lamblia DNA [Presence] in Stool by NAA with probe detection

0.00

-0.00

0.0

1.0

—

Mortality – FinRegistry

↥

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

↥

Index endpoint: ST19_CRUSHI_INJURY_HEAD – Crushing injury of head

GWS hits: -

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

≡ Risteys

R13

FinnGen R12 + FinRegistry

FinnGen R11 + FinRegistry

FinnGen R10 + FinRegistry

FinnGen R10

FinnGen R9

FinnGen R8

FinnGen R7

FinnGen R6

FinnGen R5

FinnGen R4

FinnGen R3

Crushing injury of head

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

1. Apply sex-specific rule

2. Check conditions

3. Check pre-conditions, main-only, mode, registry filters

4. Check minimum number of events

5. Include endpoints

6. Filter based on genotype QC (FinnGen only)

All original rules

Similar endpoints

Case counts by codes

Upset plot

Case counts by code for Crushing injury of head (ST19_CRUSHI_INJURY_HEAD)

Summary Statistics

-FinRegistry-

-FinnGen-

Key figures

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

CodeWAS

Matched cohort

LabWAS

Mortality – FinRegistry

Relationships between endpoints