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Viral conjunctivitis

EFO Endpoint Browser PheWeb

AB1_VIRAAL_CONJUNCT

Endpoint definition

↥

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — B30
  • Hospital discharge: ICD-9 — 07[7]
  • Hospital discharge: ICD-8 — 07[8]
  • Cause of death: ICD-10 — B30
  • Cause of death: ICD-9 — 07[7]
  • Cause of death: ICD-8 — 07[8]

2 out of 7 registries used, show all original rules.

799

4. Check minimum number of events

None

799

5. Include endpoints

None

799

6. Filter based on genotype QC (FinnGen only)

799

Control definitions (FinnGen only)

Control exclude
AB1_OTHER_VIRAL

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF5

Case counts by codes

↥

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 6693 3672 2988
Only index persons 6103 3418 2685
Unadjusted period prevalence (%)
Whole population 0.10 0.11 0.08
Only index persons 0.12 0.13 0.10
Median age at first event (years)
Whole population 32.92 35.43 29.78
Only index persons 34.62 36.51 32.22

-FinnGen-

Key figures

All Female Male
Number of individuals 799 528 271
Unadjusted period prevalence (%) 0.16 0.18 0.12
Median age at first event (years) 41.74 41.23 42.71

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS (R11)

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
705
Matched controls
7050
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
H13.1*B30.1
ICD-10 Finland
Conjunctivitis due to adenovirus
+∞
224.3
203
*
H19.2*B30.0
ICD-10 Finland
Epidemic keratoconjunctivitis
+∞
205.5
187
*
B30.9
ICD-10 Finland
Viral conjunctivitis, unspecified
201.9
116.3
118
7
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
4.1
67.0
398
1690
B30.1
ICD-10 Finland
Conjunctivitis due to adenovirus
342.1
62.4
62
*
H10.3
ICD-10 Finland
Acute conjunctivitis, unspecified
8.3
57.4
136
197
B30.0
ICD-10 Finland
Keratoconjunctivitis due to adenovirus
+∞
53.8
51
*
H13.1*B30.8
ICD-10 Finland
Other viral conjunctivitis
+∞
45.3
43
*
S01AD03
ATC
aciclovir; ophthalmic
9.6
39.2
83
97
S01CA01
ATC
dexamethasone and antiinfectives; ophthalmic (ophth., corticosteroids and antiinfectives in comb.)
3.0
36.1
276
1242
H16.9
ICD-10 Finland
Keratitis, unspecified
14.7
30.8
52
38
H10.9
ICD-10 Finland
Conjunctivitis, unspecified
4.5
24.1
89
217
H16.2
ICD-10 Finland
Keratoconjunctivitis
19.0
20.6
31
17
H04.10
ICD-10 Finland
Dry eye syndrome
3.2
18.0
100
343
H10
ICD-10 Finland
Conjunctivitis
3.5
15.4
75
233
S01GX01
ATC
cromoglicic acid; ophthalmic
2.2
14.7
185
999
F03
ICPC
Eye discharge
3.3
13.8
70
225
H19.1*B00.5
ICD-10 Finland
Herpesviral keratoconjunctivitis
16.6
13.5
21
13
Z01.0
ICD-10 Finland
Examination of eyes and vision
2.3
13.1
130
625
H01.0
ICD-10 Finland
Blepharitis
3.5
12.9
61
185
0779X
ICD-9 Finland
Other diseases of conjunctiva due to viruses and Chlamydiae, Unspecified diseases of conjunctiva due to viruses and Chlamydiae
+∞
12.5
12
*
F29
ICPC
Eye symptom/complaint other
3.0
12.2
74
268
H10.0
ICD-10 Finland
Mucopurulent conjunctivitis
3.1
11.6
63
213
B30.8
ICD-10 Finland
Other viral conjunctivitis
+∞
11.5
11
*
XCW99
NOMESCO Finland
Other investigative procedure of eye
2.7
11.1
80
324
H20.0
ICD-10 Finland
Acute and subacute iridocyclitis
3.9
10.6
43
116
WX002
NOMESCO Finland
Sedation and analgesia
2.1
9.9
129
694
F02
ICPC
Red eye
3.5
9.7
44
131
H57.1
ICD-10 Finland
Ocular pain
4.1
9.7
37
95
H02AB06
ATC
prednisolone; systemic
1.7
9.5
307
2225
F01
ICPC
Eye pain
4.4
9.5
33
77
L30.9
ICD-10 Finland
Dermatitis, unspecified
2.0
9.4
126
686
H20.9
ICD-10 Finland
Iridocyclitis, unspecified
7.1
9.4
22
32
H10.2
ICD-10 Finland
Other acute conjunctivitis
7.2
9.1
21
30
S01ED51
ATC
timolol, combinations; ophthalmic
3.3
8.5
41
128
R4120
NOMESCO Finland
Occupational therapy
2.8
8.4
53
198
ZXA00
NOMESCO Finland
Right side
1.8
8.4
158
970
H19.2
ICD-10 Finland
Keratitis and keratoconjunctivitis in other infectious and parasitic diseases classified elsewhere
+∞
8.3
8
*
H10.1
ICD-10 Finland
Acute atopic conjunctivitis
4.3
8.3
29
69
A02BC02
ATC
pantoprazole; systemic
1.6
8.3
402
3207
R4110
NOMESCO Finland
Physiotherapy
1.8
8.2
175
1115
ZXA05
NOMESCO Finland
Left side
1.8
8.1
153
939
J05AB01
ATC
aciclovir; systemic
1.8
8.0
146
884
J01DB01
ATC
cefalexin; oral
1.7
7.9
564
4942
R03AK06
ATC
salmeterol and fluticasone; inhalant
2.0
7.8
95
498
CG2S4
NOMESCO Finland
Photography of cornea
18.6
7.6
11
6
WW200
NOMESCO Finland
Immunization
3.7
7.5
31
87
TDM10
NOMESCO Finland
Puncture of maxillary antrum
3.1
7.3
38
127
B27.0
ICD-10 Finland
Gammaherpesviral mononucleosis
+∞
7.3
7
*
H13.1*A74.0
ICD-10 Finland
Chlamydial conjunctivitis
+∞
7.3
7
*
LC2AE
NOMESCO Finland
Ultrasound examination of uterus and parametria
2.0
7.2
96
520
H15.1
ICD-10 Finland
Episcleritis
5.7
7.1
19
34
S01XA18
ATC
ciclosporin; ophthalmic
12.2
7.1
12
10
S01GX05
ATC
lodoxamide; ophthalmic
5.9
6.9
18
31
ZXA10
NOMESCO Finland
Bilateral
1.9
6.9
109
628
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
1.8
6.9
119
706
CG2X4
NOMESCO Finland
Optical coherence tomography (OCT) of cornea
13.9
6.9
11
8
XCH00
NOMESCO Finland
Eye pressure measurement
3.6
6.9
29
83
D07CA01
ATC
hydrocortisone and antibiotics; topical
1.9
6.8
97
537
Z71.8
ICD-10 Finland
Other specified counselling
1.6
6.8
179
1207
D11
ICPC
Diarrhoea
1.9
6.5
93
515
J01AA02
ATC
doxycycline; systemic
1.5
6.5
504
4357
H10.5
ICD-10 Finland
Blepharoconjunctivitis
4.3
6.5
22
52
L17
ICPC
Foot/toe symptom/complaint
1.7
6.4
150
977
J05AB11
ATC
valaciclovir; oral
1.9
6.4
90
498
R03AC03
ATC
terbutaline; inhalant
1.9
6.3
99
569
R03AC02
ATC
salbutamol; inhalant
1.5
6.3
357
2874
B30.2
ICD-10 Finland
Viral pharyngoconjunctivitis
+∞
6.3
6
*
07810
ICD-8 Finland
Other viral diseases of the conjunctiva, Epidemic keratoconjunctivitis
+∞
6.3
6
*
N02AJ06
ATC
codeine and paracetamol; systemic
1.5
6.1
241
1788
J01DA01
ATC
[U] cefalexin; systemic
1.5
6.1
417
3480
CJB10
NOMESCO Finland
Laser discission of secondary cataract
2.9
6.1
35
124
M01AH05
ATC
etoricoxib; oral
1.5
6.1
375
3058
XF600
NOMESCO Finland
Bloodpressure measurement
2.5
6.1
44
181
114
Kela drug reimbursment
Glaucoma
2.7
6.1
40
156
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.5
6.0
351
2829

LabWAS

↥
OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
64
23
30.16
95.68
1.1
1.2
—
—
—
0
0
179
693
3.04
34.13
2.0
1.5
—
—
—
0
0
21
15
14.35
22.85
1.2
1.3
—
—
—
0
0
324
2049
1.98
18.67
8.1
5.7
—
—
—
0
0
268
1612
2.00
17.63
7.6
6.4
—
—
—
0
0
172
886
2.20
17.05
3.3
2.7
2.7
2.7
e6/l
0.01
92
470
400
2878
1.78
14.17
9.9
8.6
0.0
0.0
e9/l
0.02
304
2374
238
1498
1.84
12.95
4.3
3.5
94.3
94.5
%
0.04
233
1451
397
2917
1.72
12.51
9.0
5.8
0.7
0.7
%
0.50
374
2738
407
3045
1.69
11.72
9.0
5.9
8.3
8.3
%
0.19
385
2871
572
4693
1.77
11.69
4.3
3.8
11.1
10.3
mm/h
0.72
542
4365
405
3031
1.68
11.61
8.9
5.7
3.0
2.8
%
0.96
383
2834
424
3215
1.68
11.54
8.7
5.7
0.6
0.6
e9/l
0.27
368
2816
425
3229
1.68
11.44
8.7
5.7
0.0
0.0
e9/l
0.35
368
2829
242
1581
1.76
11.39
4.0
2.8
0.2
0.4
e6/l
0.64
180
1175
261
1743
1.74
11.36
4.1
2.9
21.4
67.9
e6/l
2.56
199
1326
415
3163
1.65
10.80
8.9
5.7
29.5
29.0
%
0.43
397
2970
433
3345
1.64
10.60
9.1
6.1
0.2
0.2
e9/l
0.18
389
2966
410
3125
1.64
10.59
8.5
5.5
56.1
56.7
%
0.51
391
2944
432
3338
1.64
10.55
8.7
5.7
1.9
2.0
e9/l
0.10
389
2984
471
3751
1.62
9.92
11.3
8.7
3.8
4.0
e9/l
1.56
414
3286
296
2118
1.63
9.59
4.9
3.3
31.8
102.8
e6/l
2.12
207
1433
659
5755
1.83
9.53
18.7
13.9
13.4
13.5
%
0.68
650
5655
178
1115
1.77
9.47
3.4
2.4
541.0
552.8
mosm/kgh2o
0.26
155
959
43
155
2.88
9.05
2.4
3.3
—
—
—
0
0
156
957
1.78
8.87
1.4
1.3
330.0
519.4
titre
1.04
28
195
139
826
1.83
8.77
2.0
2.0
—
—
—
0
0
229
1567
1.65
8.71
4.1
2.8
—
—
—
0
0
147
892
1.79
8.65
2.6
2.4
116.9
119.3
ug/g
0.04
117
707
182
1174
1.71
8.65
1.3
1.3
11.9
13.5
u/ml
0.11
67
497
105
576
1.95
8.47
2.9
2.4
32.1
33.5
u/l
0.17
96
493
360
2757
1.56
8.45
7.9
6.1
1.2
1.2
mmol/l
0.46
327
2352
234
1630
1.62
8.21
5.8
3.6
7.4
7.4
ph
0.21
25
302
216
1500
1.60
7.59
2.6
2.3
4432.9
5830.4
umol/l
0.22
189
1329
181
1204
1.65
7.57
1.4
1.3
17.0
30.7
iu/ml
1.45
48
400
206
1431
1.59
7.18
1.5
1.4
2.1
2.3
g/l
0.87
120
908
203
1408
1.59
7.12
3.4
3.2
—
—
—
0
0
321
2466
1.50
7.06
7.5
5.6
1.2
1.2
mmol/l
1.01
300
2258
722
6639
1.91
6.85
15.4
11.3
20.1
21.3
mg/l
0.47
575
5102
79
428
1.94
6.60
8.7
8.8
—
—
—
0
0
116
723
1.71
6.14
1.7
1.4
—
—
—
0
0
83
470
1.85
6.07
5.8
3.8
1.4
1.9
mmol/l
0.62
73
380
546
4740
1.48
6.07
8.6
6.7
77.1
76.5
u/l
0.13
525
4469
510
4390
1.45
5.77
4.9
3.8
—
—
—
0
0
83
481
1.81
5.64
5.8
3.8
—
—
—
0
0
304
2393
1.44
5.57
5.5
4.4
36.9
36.5
g/l
0.66
289
2238
36
154
2.40
5.48
1.4
1.2
—
—
—
0
0
169
1188
1.54
5.45
3.2
2.3
4.7
6.7
e6/l
1.31
149
1053
668
6115
1.56
5.16
5.2
4.6
3.7
2.0
mu/l
0.42
633
5704
225
1699
1.45
5.07
2.4
1.9
—
—
—
0
0
51
262
2.01
4.99
4.4
3.0
—
—
—
0
0
218
1641
1.45
4.98
1.3
1.3
0.9
1.8
u/ml
1.23
48
465
410
3451
1.39
4.91
5.2
4.4
6.5
6.5
mmol/l
0.36
382
3175
13
32
4.11
4.91
3.2
2.7
721.3
499.9
u/ml
0.39
13
32
107
693
1.63
4.88
3.3
2.5
5.5
7.1
umol/l
0.82
97
589
89
550
1.70
4.86
1.2
1.2
—
—
—
0
0
34
152
2.29
4.72
1.4
1.9
164.4
143.1
e6/l
0.06
25
122
34
152
2.29
4.72
1.4
1.8
3.0
13.0
e6/l
1.25
25
117
18
58
3.15
4.66
1.2
1.2
—
—
—
0
0
321
2612
1.38
4.65
2.1
2.0
—
—
—
0
0
491
4281
1.38
4.62
3.1
3.2
—
—
—
0
0
14
39
3.64
4.50
1.3
1.3
—
—
—
0
0
79
483
1.71
4.49
3.5
2.7
11.5
10.3
g/l
1.57
72
441
58
325
1.85
4.43
1.1
1.1
—
—
—
0
0
20
71
2.86
4.41
1.8
2.3
—
—
—
0
0
134
937
1.52
4.38
2.3
1.6
—
—
—
0
0
746
7075
1.82
4.36
11.9
8.9
27.2
26.8
u/l
0.20
731
6871
142
1008
1.50
4.32
3.6
3.3
194.2
433.0
ng/l
0.84
95
669
47
251
1.93
4.16
7.8
10.8
24.7
24.2
mmol/l
0.51
47
238
703
6584
1.56
4.10
15.3
12.3
139.7
139.6
mmol/l
0.66
688
6410
704
6603
1.56
3.99
15.5
12.4
3.9
3.9
mmol/l
1.81
688
6412
210
1627
1.39
3.98
1.6
1.6
1.4
1.4
mmol/l
0.05
185
1402
30
138
2.22
3.94
1.4
1.9
—
—
—
0
0
270
2184
1.36
3.91
2.0
1.8
99.5
97.3
pmol/l
0.31
138
1144
26
113
2.34
3.88
1.2
1.2
—
—
—
0
0
17
60
2.87
3.81
1.7
1.9
—
—
—
0
0
374
3187
1.33
3.77
5.2
4.4
0.0
0.0
estimate
0.50
52
635
213
1673
1.37
3.68
2.9
2.5
—
—
—
0
0
184
1411
1.40
3.68
5.4
4.0
—
—
—
0
0
91
609
1.56
3.63
1.9
1.5
—
—
—
0
0
17
62
2.78
3.60
3.1
2.1
104.7
105.7
mmol/l
0.40
17
62
17
62
2.78
3.60
3.1
2.1
—
—
—
0
0
17
62
2.78
3.60
3.1
2.1
3.9
4.1
mmol/l
0.80
17
62
364
3109
1.31
3.54
5.8
5.6
9.9
10.4
umol/l
0.88
345
2931
27
127
2.17
3.39
2.9
2.0
—
—
—
0
0
374
3221
1.30
3.37
3.6
3.2
0.0
0.0
estimate
0.80
48
613
15
54
2.81
3.27
1.1
1.3
—
—
—
0
0
681
6402
1.43
3.22
17.7
12.1
40.3
40.5
%
0.26
574
5075
11
33
3.37
3.20
1.5
1.6
—
—
—
0
0
21
91
2.34
3.19
1.6
1.5
—
—
—
0
0
38
208
1.87
3.18
1.2
1.1
—
—
—
0
0
27
131
2.10
3.15
1.8
1.6
5467.7
16676.6
e6/l
1.37
18
95
16
61
2.66
3.15
1.8
2.6
0.8
1.2
e9/l
—
9
35
357
3080
1.29
3.09
3.1
2.7
112.2
96.2
ug/l
0.46
342
2888
32
167
1.95
3.08
1.3
1.6
402.6
461.6
mg/l
0.83
32
157
567
5198
1.31
3.03
4.5
3.9
14.4
14.5
pmol/l
0.65
533
4806
185
1462
1.35
3.02
1.9
1.7
0.9
1.0
mg/l
0.30
142
1109
365
3168
1.28
2.98
3.6
3.2
0.0
0.0
estimate
0.00
51
620
777
7552
2.05
2.89
21.8
16.7
4.5
4.6
e12/l
0.07
755
7389
9
22
4.13
2.89
1.2
1.2
—
—
—
0
0
60
387
1.60
2.84
2.4
1.7
2.2
1.3
g/l
0.92
55
359
17
71
2.42
2.81
1.5
1.5
—
—
—
0
0
61
396
1.59
2.81
5.9
3.7
101.5
76.3
ng/l
1.20
53
360
5
6
8.38
2.75
1.2
1.0
—
—
—
0
0
7
14
5.03
2.73
1.3
1.1
—
—
—
0
0
26
132
2.00
2.73
2.0
1.4
—
—
—
0
0
13
48
2.74
2.73
2.0
2.6
15.8
12.8
%
—
6
27
22
105
2.13
2.71
1.5
1.6
—
—
—
0
0
127
963
1.38
2.69
3.3
2.7
2.4
2.4
mmol/l
0.26
107
847
16
67
2.42
2.64
1.3
1.4
—
—
—
0
0
776
7555
1.94
2.61
21.9
16.8
6.7
6.6
e9/l
0.12
754
7383
202
1651
1.30
2.58
2.0
2.0
143.4
230.8
u/l
1.36
197
1561
95
691
1.43
2.56
1.4
1.3
—
—
—
0
0
171
1377
1.31
2.43
2.0
1.6
—
—
—
0
0
40
243
1.68
2.42
1.3
1.2
—
—
—
0
0
734
7063
1.48
2.42
11.9
10.4
—
—
—
0
0
25
132
1.92
2.38
5.9
3.6
—
—
—
0
0
77
547
1.45
2.37
7.0
8.9
1.0
1.1
mmol/l
0.08
65
432
8
22
3.66
2.37
1.0
1.5
32.8
27.5
umol/l
—
8
22
774
7544
1.83
2.36
21.9
16.7
252.6
257.4
e9/l
1.52
755
7393
228
1912
1.27
2.36
3.5
3.1
2.4
2.4
mmol/l
0.03
205
1715
18
85
2.14
2.30
1.1
1.3
—
54.0
—
0
7
211
1758
1.27
2.30
3.3
3.1
8.1
8.0
mmol/l
0.07
171
1500
228
1918
1.26
2.29
3.0
2.1
—
—
—
0
0
11
41
2.71
2.28
1.4
1.4
5.4
7.8
u/l
0.73
11
36
11
41
2.71
2.28
2.2
2.0
—
—
—
0
0
177
1445
1.29
2.26
2.2
2.0
—
—
—
0
0
109
832
1.36
2.23
2.0
1.8
—
—
—
0
0
92
683
1.39
2.23
1.5
1.4
—
—
—
0
0
51
339
1.54
2.17
1.1
1.1
—
—
—
0
0
20
101
2.01
2.17
1.1
1.2
—
—
—
0
0
27
152
1.80
2.14
1.4
1.5
4.0
3.6
mmol/l
0.56
27
140
150
1210
1.30
2.10
1.4
1.5
20.3
21.0
nmol/l
0.27
130
1050
5
10
5.02
2.07
1.0
1.1
—
—
—
0
0
7
21
3.35
1.97
2.3
2.0
—
—
—
0
0
34
213
1.62
1.88
6.6
9.4
—
—
—
0
0
40
261
1.56
1.88
2.5
2.2
—
—
—
0
0
33
207
1.62
1.82
1.2
1.2
—
—
—
0
0
5
12
4.19
1.82
1.2
1.2
—
—
—
0
0
5
12
4.19
1.82
8.4
5.8
—
—
—
0
0
610
5780
1.23
1.76
5.5
4.9
38.4
38.8
mmol/mol
0.48
583
5453
20
111
1.82
1.70
1.1
1.1
7.4
6.0
u/ml
—
10
44
55
394
1.43
1.68
1.3
1.2
—
—
—
0
0
29
181
1.62
1.65
1.1
1.2
—
660.0
—
0
6
34
508
0.65
1.64
5.4
3.5
—
—
—
0
0
5
14
3.59
1.61
1.0
1.0
4.5
5.9
mg/g
—
5
14
6
20
3.01
1.58
1.7
2.6
—
—
—
0
0
15
78
1.94
1.55
1.1
1.1
—
—
—
0
0
15
78
1.94
1.55
5.0
2.9
1.3
1.0
%
—
10
64
14
71
1.99
1.54
1.6
1.5
—
—
—
0
0
14
71
1.99
1.54
1.6
1.5
—
—
—
0
0
14
71
1.99
1.54
1.6
1.5
—
—
—
0
0
14
71
1.99
1.54
1.6
1.5
—
—
—
0
0
117
953
1.27
1.54
1.5
1.4
—
—
—
0
0
20
115
1.76
1.53
3.1
3.7
—
—
—
0
0
102
818
1.28
1.52
1.2
1.2
—
—
—
0
0
91
719
1.30
1.52
3.4
2.2
23.1
23.5
%
0.11
85
618
15
79
1.92
1.50
1.3
1.3
—
—
—
0
0
45
318
1.44
1.49
2.3
2.1
—
—
—
0
0
184
1581
1.21
1.48
4.2
3.9
9.7
10.0
mg/mmol
0.03
113
1003
61
458
1.36
1.44
2.5
2.1
15.5
12.9
nmol/l
1.50
49
420
5
16
3.14
1.44
1.0
1.0
—
—
—
0
0
77
600
1.31
1.43
2.6
1.9
345.4
364.3
nmol/l
0.44
68
553
55
409
1.37
1.39
1.8
1.8
—
—
—
0
0
16
89
1.81
1.38
2.8
2.6
—
—
—
0
0
55
410
1.37
1.37
1.8
1.8
—
—
—
0
0
6
23
2.62
1.37
3.2
4.0
—
—
—
0
0
174
1500
1.20
1.36
3.4
3.2
62.2
237.7
mg/l
1.26
112
969
119
987
1.24
1.35
1.8
1.7
—
—
—
0
0
325
2958
1.17
1.34
4.2
3.9
—
—
—
0
0
10
47
2.14
1.34
2.3
3.3
—
—
—
0
0
682
6591
1.24
1.34
4.6
4.2
2.9
2.9
mmol/l
0.46
656
6180
63
483
1.33
1.32
2.7
4.3
2.7
31.7
ug/l
1.02
46
380
55
413
1.36
1.32
1.9
1.8
—
—
—
0
0
104
853
1.25
1.31
3.0
2.2
13.8
13.9
umol/l
0.04
98
786
166
1430
1.20
1.31
2.4
2.1
2.7
2.9
mg/l
0.43
146
1240
17
99
1.73
1.28
1.3
1.1
—
—
—
0
0
37
261
1.44
1.27
1.6
1.2
—
—
—
0
0
9
44
2.06
1.27
1.2
1.1
—
—
—
0
0
18
107
1.70
1.26
1.3
1.1
—
—
—
0
0
54
408
1.35
1.25
1.9
1.7
—
—
—
0
0
6
25
2.41
1.24
1.0
1.0
280.8
230.4
ng/l
—
6
14
8
36
2.23
1.24
4.6
1.9
—
—
—
0
0
9
45
2.01
1.23
2.6
4.9
11.8
12.6
%
—
9
45
234
2088
1.17
1.23
6.6
6.7
1.1
1.2
inr
0.35
59
675
34
238
1.45
1.22
1.6
1.4
—
—
—
0
0
6
26
2.32
1.19
1.0
1.4
137.0
165.0
nmol/l
—
6
26
8
38
2.12
1.18
1.0
1.1
—
—
—
0
0
20
125
1.62
1.18
1.1
1.0
8.0
4.4
u/ml
—
8
44
0
33
0.00
1.16
0.0
1.8
—
—
—
0
0
36
258
1.41
1.15
8.8
12.1
—
—
—
0
0
21
134
1.58
1.15
6.3
3.8
57.1
56.6
%
0.08
21
134
648
6255
1.19
1.15
4.4
3.9
5.8
5.8
mmol/l
0.00
608
5800
95
786
1.24
1.12
3.1
2.2
2.3
2.4
g/l
0.58
88
731
34
243
1.42
1.11
1.6
1.5
—
—
—
0
0
71
569
1.27
1.10
1.4
1.2
201.2
142.0
iu/ml
0.80
30
238
37
269
1.39
1.10
2.7
1.7
—
—
—
0
0
5
21
2.39
1.09
1.6
1.7
—
—
—
0
0
43
322
1.35
1.08
1.4
1.8
—
—
—
0
0
60
473
1.29
1.07
1.4
1.3
25.6
26.7
iu/l
0.11
52
398
26
178
1.48
1.06
2.4
2.3
—
—
—
0
0
33
238
1.40
1.04
1.6
1.4
—
—
—
0
0
49
379
1.31
1.01
1.8
1.8
—
—
—
0
0
20
132
1.53
0.98
2.2
1.8
—
—
—
0
0
7
36
1.95
0.97
1.1
1.2
—
—
—
0
0
14
85
1.66
0.94
2.5
1.7
—
—
—
0
0
7
37
1.90
0.94
1.1
1.0
—
—
—
0
0
22
150
1.48
0.93
1.1
1.1
1.3
3.7
u/ml
—
6
34
37
278
1.35
0.93
1.6
2.4
—
—
—
0
0
21
142
1.49
0.93
1.6
1.2
161.7
246.3
u/ml
1.52
15
86
9
52
1.74
0.92
1.0
1.1
—
4.4
—
0
11
23
159
1.46
0.92
3.2
2.4
—
—
—
0
0
48
376
1.29
0.92
2.7
2.3
—
—
—
0
0
669
6508
1.17
0.91
4.2
3.9
4.8
4.8
mmol/l
0.00
646
6142
6
29
2.08
0.89
2.2
2.2
8.2
11.2
mg/l
—
6
21
84
707
1.21
0.88
10.9
4.9
1.1
1.0
mmol/l
0.95
79
662
34
256
1.34
0.86
1.7
1.6
—
—
—
0
0
229
2094
1.13
0.84
3.0
3.1
201.3
49.9
ng/l
0.96
124
1232
15
97
1.56
0.81
1.2
1.2
—
—
—
0
0
41
322
1.29
0.79
1.5
1.3
166.2
238.2
miu/ml
0.92
23
169
16
106
1.52
0.79
1.3
1.1
—
—
—
0
0
6
33
1.82
0.79
1.0
1.1
1565.8
1715.6
miu/ml
—
6
33
0
26
0.00
0.78
0.0
4.8
—
—
—
0
0
69
578
1.21
0.77
20.3
17.6
1.0
1.2
inr
—
8
89
21
149
1.42
0.76
1.0
1.1
6.8
5.7
u/ml
0.10
12
77
15
99
1.53
0.76
2.1
3.8
—
—
—
0
0
24
175
1.38
0.75
1.1
1.1
2.4
1.1
u/ml
0.25
11
70
5
24
2.09
0.74
1.0
1.0
—
—
—
0
0
7
38
1.85
0.73
1.1
1.1
—
—
—
0
0
50
411
1.23
0.69
1.2
1.2
—
—
—
0
0
16
110
1.46
0.68
1.5
1.2
10.6
5.8
u/ml
—
8
45
7
42
1.67
0.68
1.1
1.1
—
—
—
0
0
7
43
1.63
0.67
1.1
1.1
—
—
—
0
0
20
145
1.39
0.66
1.1
1.1
1.7
1.4
u/ml
—
7
64
53
441
1.22
0.65
1.5
2.6
4.2
4.1
e9/l
0.10
43
369
8
49
1.64
0.62
1.1
1.2
—
—
—
0
0
6
105
0.57
0.62
1.7
1.5
—
—
—
0
0
27
209
1.30
0.61
3.5
4.4
0.3
0.3
g/l
0.08
14
94
90
792
1.15
0.60
1.2
1.2
—
—
—
0
0
0
20
0.00
0.60
0.0
1.3
—
—
—
0
0
0
20
0.00
0.60
0.0
1.1
—
38.4
—
0
14
662
6482
1.12
0.60
4.1
3.8
1.5
1.5
mmol/l
0.79
632
6088
50
419
1.21
0.59
1.5
1.4
—
—
—
0
0
10
64
1.57
0.58
6.5
5.6
10.8
9.8
mg/l
—
10
58
25
193
1.30
0.58
4.2
4.3
—
—
—
0
0
7
115
0.61
0.58
1.1
1.3
—
—
—
0
0
53
448
1.20
0.58
4.9
4.1
0.4
0.5
%
0.26
15
101
11
73
1.51
0.56
2.9
1.7
—
—
—
0
0
638
6242
1.11
0.56
3.7
3.5
1.3
1.3
mmol/l
0.30
606
5854
6
38
1.58
0.54
9.5
7.8
—
—
—
0
0
254
2691
0.92
0.53
2.6
2.5
—
—
—
0
0
6
40
1.50
0.51
1.0
1.2
—
—
—
0
0
11
75
1.47
0.51
1.0
1.3
—
—
nmol/l
—
0
0
9
65
1.39
0.50
1.0
1.1
—
—
—
0
0
6
41
1.47
0.50
1.5
1.8
—
1.2
—
0
5
171
1586
1.10
0.50
5.2
4.4
—
—
—
0
0
83
927
0.88
0.48
1.3
1.3
—
—
—
0
0
55
477
1.16
0.47
1.5
1.4
—
—
—
0
0
7
48
1.46
0.47
1.0
1.1
—
—
—
0
0
7
48
1.46
0.47
1.6
2.6
—
—
—
0
0
7
48
1.46
0.47
2.4
1.8
8.1
6.5
mmol/l
—
7
35
20
156
1.29
0.45
1.2
1.1
—
—
—
0
0
10
69
1.45
0.44
5.1
3.0
—
—
—
0
0
23
184
1.26
0.43
3.0
2.0
2.6
5.9
iu/l
—
8
77
11
78
1.42
0.43
1.0
1.3
—
—
—
0
0
16
122
1.32
0.42
1.6
2.3
3.4
4.8
umol/l
0.92
11
87
8
58
1.38
0.41
1.0
2.3
—
—
—
0
0
27
222
1.22
0.41
1.2
1.3
—
—
—
0
0
0
15
0.00
0.41
0.0
1.0
—
—
—
0
0
0
15
0.00
0.41
0.0
1.0
—
—
—
0
0
0
15
0.00
0.41
0.0
1.0
—
—
—
0
0
23
186
1.24
0.40
1.3
1.4
352.9
294.6
ug/g
0.70
12
106
0
17
0.00
0.40
0.0
1.1
—
—
—
0
0
0
17
0.00
0.40
0.0
1.1
—
—
—
0
0
5
34
1.47
0.40
1.0
1.1
338.3
159.4
iu/ml
—
5
34
56
496
1.14
0.38
5.0
4.2
0.4
1.0
%
2.24
20
144
140
1307
1.09
0.37
4.0
4.2
2.5
2.1
ug/l
0.17
129
1186
8
115
0.69
0.37
1.9
1.6
—
—
—
0
0
34
396
0.85
0.37
2.7
2.2
3856.8
2654.3
u/l
0.22
15
165
10
72
1.39
0.37
3.4
1.6
18.8
21.4
nmol/l
—
10
67
28
236
1.19
0.35
4.1
2.9
—
—
—
0
0
6
43
1.40
0.35
1.5
1.2
—
—
—
0
0
48
424
1.14
0.35
4.8
3.6
1.2
1.2
mmol/l
0.01
41
366
6
88
0.68
0.33
1.5
1.2
11.4
19.2
u/l
—
6
76
44
390
1.14
0.31
3.3
2.8
79.7
71.9
e9/l
0.50
29
291
19
156
1.22
0.31
1.2
1.1
—
—
—
0
0
56
505
1.12
0.31
1.9
1.7
—
—
—
0
0
7
56
1.25
0.29
1.9
1.3
—
—
—
0
0
198
1892
1.06
0.29
2.9
2.3
58.8
55.8
u/l
0.37
183
1751
16
130
1.24
0.29
1.3
1.4
2.4
2.8
ug/l
0.39
16
115
52
471
1.11
0.27
5.3
4.3
0.0
0.2
%
4.18
18
127
38
338
1.13
0.27
3.9
2.8
7.4
7.4
ph
—
5
45
9
72
1.25
0.25
2.9
2.2
—
—
—
0
0
161
1685
0.94
0.25
3.6
3.5
0.0
0.0
estimate
1.08
52
629
83
776
1.08
0.24
2.8
2.7
0.7
0.7
ug/l
0.06
49
454
5
39
1.28
0.23
1.4
1.3
—
—
—
0
0
18
153
1.18
0.22
1.3
1.2
—
—
—
0
0
38
343
1.11
0.22
3.9
2.8
5.1
5.1
kpa
0.23
38
322
179
1859
0.95
0.21
3.2
2.8
—
—
—
0
0
0
11
0.00
0.21
0.0
1.1
—
—
—
0
0
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
0
11
0.00
0.21
0.0
2.9
—
6644.0
—
0
11
0
11
0.00
0.21
0.0
1.5
—
—
—
0
0
0
12
0.00
0.21
0.0
3.1
—
—
—
0
0
0
13
0.00
0.21
0.0
2.9
—
—
—
0
0
33
297
1.12
0.20
4.7
6.2
—
—
—
0
0
0
14
0.00
0.20
0.0
2.1
—
1.2
—
0
14
93
880
1.06
0.20
1.6
1.7
1099.2
1192.3
nmol/l
0.55
71
684
6
50
1.20
0.19
1.2
3.7
—
—
—
0
0
6
51
1.18
0.19
1.0
1.2
—
—
—
0
0
37
337
1.10
0.19
2.4
2.9
179.2
158.5
ng/l
0.11
31
298
48
445
1.08
0.18
5.6
4.4
0.0
0.2
%
1.38
14
105
7
61
1.15
0.17
1.1
1.1
—
—
—
0
0
53
566
0.93
0.16
3.6
3.6
—
—
—
0
0
6
77
0.78
0.15
1.7
1.3
—
—
—
0
0
22
198
1.11
0.14
1.2
1.4
100.2
192.0
pmol/l
0.51
22
193
134
1296
1.04
0.14
2.6
2.9
1614.4
985.9
ng/l
0.63
118
1076
46
433
1.07
0.13
3.8
3.1
—
—
—
0
0
12
104
1.16
0.12
2.1
2.4
46.5
32.6
umol/l
1.12
12
89
20
183
1.10
0.10
7.8
4.2
1.8
1.3
mg/l
0.62
20
169
20
184
1.09
0.09
4.6
3.8
1.5
1.3
mmol/l
0.32
20
178
158
1548
1.03
0.09
3.5
3.2
—
—
—
0
0
196
1994
0.98
0.08
1.6
1.6
—
—
—
0
0
5
64
0.78
0.08
3.6
3.0
—
—
—
0
0
18
166
1.09
0.08
2.2
2.1
90.4
258.3
ug/l
2.86
18
153
8
75
1.07
0.07
1.3
1.2
—
—
—
0
0
7
81
0.86
0.07
1.0
1.0
1.3
1.4
g/l
—
7
74
40
383
1.05
0.07
2.3
2.3
11.9
6.3
ug/l
0.47
34
346
9
88
1.02
0.07
2.8
2.0
—
—
—
0
0
9
100
0.90
0.06
1.1
1.5
—
—
—
0
0
15
139
1.08
0.05
1.7
2.5
38.5
112.7
ug/min
—
7
89
56
571
0.98
0.03
1.5
1.4
—
—
—
0
0
15
142
1.06
0.02
1.0
1.1
—
—
—
0
0
113
1123
1.01
0.01
1.5
1.6
450.2
28147820.6
pmol/l
1.31
99
977
12
115
1.04
0.00
5.3
2.4
—
—
—
0
0
13
134
0.97
0.00
2.9
2.4
24.0
24.6
mmol/l
0.28
13
118
11
107
1.03
0.00
3.3
2.1
—
—
—
0
0
16
163
0.98
0.00
1.4
1.2
—
—
—
0
0
11
111
0.99
0.00
6.6
2.8
5.2
5.0
kpa
0.48
11
111
11
111
0.99
0.00
6.6
2.8
8.4
8.8
kpa
0.41
11
111
5
54
0.93
0.00
1.2
1.1
302.0
286.7
mg/l
—
5
48
0
8
0.00
0.00
0.0
1.1
—
15.4
—
0
8
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
0.00
0.0
2.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
3.0
—
—
—
0
0
5
57
0.88
0.00
1.6
2.9
11.4
20.7
mu/l
—
5
57
0
5
0.00
0.00
0.0
1.0
—
362.8
—
0
5
139
1390
1.00
0.00
3.4
3.3
1.0
1.0
kg/l
0.29
17
182
13
130
1.00
0.00
6.4
2.6
9.0
8.4
kpa
0.63
13
121
0
8
0.00
0.00
0.0
1.3
—
—
—
0
0
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
0
8
0.00
0.00
0.0
1.3
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
21.0
—
0
5
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0

Mortality – FinRegistry

↥

Association

Association between endpoint AB1_VIRAAL_CONJUNCT and mortality.

Females

Parameter HR [95% CI] p-value
AB1_VIRAAL_CONJUNCT 1.087 [0.87, 1.35] 0.453
Birth year 0.995 [0.99, 1.0] 0.218

During the follow-up period (1.1.1998 — 31.12.2019), 135 out of 3306 females with AB1_VIRAAL_CONJUNCT died.

Males

Parameter HR [95% CI] p-value
AB1_VIRAAL_CONJUNCT 1.091 [0.88, 1.35] 0.432
Birth year 0.989 [0.98, 1.0] 0.026

During the follow-up period (1.1.1998 — 31.12.2019), 130 out of 2559 males with AB1_VIRAAL_CONJUNCT died.

Mortality risk

Mortality risk for people of age

years, who have AB1_VIRAAL_CONJUNCT.

N-year risk Females Males
1 0.102% 0.262%
5 0.715% 1.337%
10 1.664% 3.385%
15 3.117% 6.616%
20 5.533% 10.786%

Relationships between endpoints

↥

Index endpoint: AB1_VIRAAL_CONJUNCT – Viral conjunctivitis

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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