pityriasis rosea: a skin rash. It is benign but may inflict substantial discomfort in certain cases.Classically, it begins with a single "herald patch" lesion, followed in 1 or 2 weeks by a generalized body rash lasting up to 12 weeks, however usually around 6 - 8.
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleNone |
520210 |
2. Check conditionsNone |
520210 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
284 |
4. Check minimum number of eventsNone |
284 |
5. Include endpointsNone |
284 |
6. Filter based on genotype QC (FinnGen only) |
284 |
Control definitions (FinnGen only)
- Control exclude
- L12_PAPULOSQUAMOUS
Extra metadata
- Level in the ICD hierarchy
- 4
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- L40-L45
- Name in latin
- Pityriasis rosea
Similar endpoints
↥List of similar endpoints to
Pityriasis rosea
based on the number of shared cases.
Similar with more cases:
- Parapsoriasis
- Papulosquamous disorders
- Diseases of the skin and subcutaneous tissue
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 2464 | 1398 | 1053 |
| Only index persons | 2221 | 1287 | 934 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.04 | 0.04 | 0.03 |
| Only index persons | 0.04 | 0.05 | 0.04 |
| Median age at first event (years) | |||
| Whole population | 25.89 | 28.71 | 22.08 |
| Only index persons | 25.96 | 28.92 | 21.89 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 284 | 204 | 80 |
| Unadjusted period prevalence (%) | 0.06 | 0.07 | 0.04 |
| Median age at first event (years) | 32.40 | 31.72 | 34.15 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
No data
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 255
- Matched controls
- 2548
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
L42
ICD-10 Finland
Pityriasis rosea
1795.9
276.5
221
9
69630
ICD-8 Finland
Psoriasis and similar disorders, Pityriasis rosea
+∞
28.7
27
*
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
5.5
14.7
45
95
D07AC01
ATC
betamethasone; topical
2.8
12.2
101
482
L30.9
ICD-10 Finland
Dermatitis, unspecified
3.0
8.8
54
209
E0000UV
ATC
NA
2.2
8.4
115
687
Z01.5
ICD-10 Finland
Diagnostic skin and sensitization tests
3.3
7.8
39
131
R21
ICD-10 Finland
Rash and other nonspecific skin eruption
5.1
7.5
23
49
6963A
ICD-9 Finland
Psoriasis and similar disorders, Pityriasis rosea
+∞
7.3
7
*
D07AB08
ATC
desonide; topical
3.2
6.9
38
134
D07BB04
ATC
hydrocortisone butyrate and antiseptics; topical
2.9
6.8
42
163
L43.8
ICD-10 Finland
Other lichen planus
+∞
6.3
6
*
L40.0
ICD-10 Finland
Psoriasis vulgaris
12.9
6.1
10
8
H02AB06
ATC
prednisolone; systemic
2.0
6.1
115
755
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
45
245
1.99
4.00
2.3
1.9
—
—
—
0
0
36
181
2.13
3.95
13.5
15.4
1.04
1.23
inr
—
7
30
245
2170
1.94
3.68
5.7
4.6
1.74
1.77
mu/l
0.15
231
2022
31
152
2.17
3.62
1.4
1.2
102.13
277.58
u/ml
0.55
26
135
98
695
1.63
3.55
3.6
2.8
—
—
—
0
0
163
1305
1.58
3.53
9.1
8.3
4.10
3.97
e9/l
0.27
151
1143
150
1185
1.56
3.40
4.3
4.7
6.39
6.47
mmol/l
0.17
135
1058
90
632
1.62
3.37
1.4
1.3
0.95
1.12
u/ml
0.21
32
162
31
157
2.09
3.35
3.5
3.6
0.64
1.90
mmol/l
0.69
25
117
55
346
1.73
3.10
3.3
3.3
217.91
326.33
ng/l
0.24
33
223
23
107
2.25
3.06
1.4
1.4
—
—
—
0
0
7
12
5.95
3.04
1.4
2.6
—
—
—
0
0
142
1128
1.52
3.01
4.0
3.2
0.00
0.00
estimate
0.00
29
209
197
1682
1.56
2.96
5.1
3.6
10.08
9.44
mm/h
0.32
187
1557
26
130
2.10
2.91
1.2
1.6
—
—
—
0
0
143
1145
1.50
2.88
4.3
3.3
0.04
0.00
estimate
0.49
27
200
18
79
2.36
2.74
1.6
1.5
—
—
—
0
0
137
1103
1.47
2.60
7.8
5.0
30.24
29.71
%
0.23
128
1036
136
1094
1.47
2.59
7.8
4.8
56.43
56.21
%
0.08
128
1029
89
659
1.51
2.55
3.2
3.1
45.85
34.16
ng/l
0.25
53
368
139
1129
1.45
2.49
5.5
4.6
0.00
0.00
estimate
0.00
29
212
236
2132
1.63
2.48
3.8
3.8
5.73
5.73
mmol/l
0.01
225
1985
43
271
1.69
2.41
2.1
1.9
—
—
—
0
0
12
46
2.68
2.39
1.1
1.0
0.93
2.00
u/ml
—
6
25
17
78
2.25
2.36
4.7
3.2
54.58
50.33
%
0.28
17
78
79
581
1.50
2.32
4.2
3.6
0.00
0.00
estimate
0.00
29
208
68
486
1.52
2.28
1.9
1.7
1.68
0.96
mg/l
0.36
52
358
7
18
3.96
2.26
1.1
1.3
—
—
—
0
0
48
318
1.61
2.23
2.4
1.9
—
—
—
0
0
117
941
1.41
2.12
5.2
6.4
1.22
1.22
mmol/l
0.54
101
791
60
427
1.51
2.05
1.4
1.3
10.81
27.54
iu/ml
2.70
21
131
130
1077
1.38
1.94
4.1
5.5
9.70
10.63
umol/l
0.75
121
1014
187
1646
1.40
1.92
6.4
6.4
79.54
73.93
u/l
0.87
180
1530
110
890
1.39
1.88
4.3
3.3
—
—
—
0
0
85
658
1.42
1.88
2.0
2.5
52.88
54.13
u/l
0.21
78
604
5
12
4.22
1.83
1.0
1.7
0.84
0.93
g/l
—
5
12
44
300
1.55
1.82
1.6
1.6
1136.72
1236.61
nmol/l
0.39
35
231
30
186
1.69
1.81
1.8
1.8
—
—
—
0
0
7
24
2.96
1.73
2.3
1.8
—
—
—
0
0
209
1893
1.39
1.68
3.9
3.7
—
—
—
0
0
7
25
2.84
1.66
1.1
1.1
—
—
—
0
0
5
14
3.62
1.62
2.8
1.5
—
—
—
0
0
252
2368
1.57
1.62
14.3
10.8
20.19
20.35
mg/l
0.02
202
1786
92
740
1.36
1.59
2.1
1.8
97.94
97.80
pmol/l
0.01
51
366
7
26
2.73
1.59
1.4
2.7
106.00
106.58
mmol/l
—
7
26
38
259
1.54
1.59
2.1
2.0
2.63
2.44
g/l
1.24
38
242
14
71
2.02
1.57
1.4
1.3
—
—
—
0
0
29
188
1.60
1.50
1.9
1.8
—
—
—
0
0
204
1856
1.35
1.48
4.9
3.9
14.52
14.48
pmol/l
0.08
194
1714
6
22
2.76
1.44
1.2
1.2
—
—
—
0
0
64
494
1.38
1.42
4.3
3.7
12.68
12.30
mg/mmol
0.02
47
302
17
97
1.80
1.38
2.8
2.6
0.44
0.95
mmol/l
—
10
65
102
849
1.31
1.38
4.8
5.7
1.22
1.22
mmol/l
0.39
91
773
6
23
2.64
1.37
1.3
1.2
0.00
1.31
promille
—
6
17
14
76
1.89
1.32
1.3
1.1
—
—
—
0
0
238
2233
1.41
1.31
3.9
3.7
1.47
1.49
mmol/l
0.41
225
2104
9
44
2.08
1.28
2.8
2.4
—
—
—
0
0
14
77
1.86
1.28
1.3
1.1
—
—
—
0
0
30
205
1.52
1.26
4.6
6.3
103.47
104.63
mmol/l
0.44
30
198
11
56
2.00
1.24
2.3
1.8
—
—
—
0
0
69
551
1.33
1.23
3.9
2.6
0.24
0.34
e6/l
0.24
58
407
33
233
1.47
1.20
2.2
2.1
20.21
25.58
%
1.60
28
201
238
2244
1.37
1.17
3.9
3.8
4.84
4.74
mmol/l
0.94
226
2121
83
686
1.30
1.16
2.7
3.0
2.38
2.35
mmol/l
1.22
71
616
41
305
1.40
1.14
3.3
2.4
6.65
2.86
e6/l
0.65
30
161
259
2482
1.49
1.11
10.3
8.4
26.41
25.87
u/l
0.22
254
2401
107
921
1.26
1.08
2.8
2.2
73.94
74.14
nmol/l
0.03
99
844
42
318
1.38
1.06
2.6
2.3
1.01
0.88
e6/l
0.14
31
173
63
509
1.31
1.04
4.1
3.3
1.01
1.02
kg/l
—
10
74
12
68
1.80
1.02
2.6
2.0
—
—
—
0
0
12
68
1.80
1.02
2.6
1.8
—
—
—
0
0
239
2268
1.34
1.01
4.2
4.1
2.92
2.84
mmol/l
0.85
227
2130
89
760
1.25
0.95
2.8
3.0
26.69
29.20
u/l
0.69
83
726
8
42
1.93
0.89
1.0
1.3
—
—
—
0
0
225
2129
1.27
0.89
11.9
9.6
91.02
90.01
ml/min/173m2
0.29
186
1685
33
248
1.37
0.88
1.8
2.0
29.83
29.47
s
0.16
33
242
29
214
1.40
0.87
3.4
3.8
30.05
32.64
%
0.63
20
143
12
72
1.70
0.86
1.3
1.1
—
—
—
0
0
10
57
1.78
0.84
1.8
1.2
—
—
—
0
0
30
224
1.38
0.84
5.5
5.5
—
—
—
0
0
6
33
1.84
0.79
2.0
1.4
—
—
—
0
0
60
501
1.25
0.77
2.3
2.0
2.86
2.81
mg/l
0.08
49
429
36
282
1.32
0.76
2.3
2.0
12.84
15.09
umol/l
1.23
36
262
181
1687
1.20
0.76
2.7
2.8
36.12
37.67
u/l
0.18
174
1610
48
392
1.27
0.75
3.0
3.0
413.84
898.84
ng/l
2.07
41
321
7
38
1.86
0.74
3.7
2.5
24.96
24.69
mmol/l
—
7
32
5
25
2.02
0.73
1.6
3.4
12.80
79.74
u/ml
—
5
25
47
386
1.26
0.70
1.9
1.7
372.18
14881407.27
pmol/l
0.50
39
336
225
2151
1.22
0.67
3.6
3.4
1.35
1.24
mmol/l
1.50
208
2019
5
28
1.80
0.66
2.2
1.5
—
—
—
0
0
49
410
1.24
0.63
1.3
1.3
9.35
9.59
u/ml
0.01
24
172
65
561
1.21
0.62
1.7
1.7
1.45
1.33
mmol/l
0.55
60
492
25
192
1.33
0.61
1.4
1.5
—
—
—
0
0
0
21
0.00
0.60
0.0
1.4
—
—
—
0
0
210
2003
1.19
0.59
5.4
4.6
38.33
38.42
mmol/mol
0.05
203
1902
6
35
1.73
0.58
1.2
1.8
13.00
13.23
%
—
6
35
6
35
1.73
0.58
1.0
1.9
—
—
—
0
0
6
35
1.73
0.58
2.3
1.7
—
—
—
0
0
8
54
1.50
0.57
1.1
1.3
—
49.72
—
0
6
6
36
1.68
0.57
2.3
4.0
53.83
57.03
%
—
6
36
19
142
1.36
0.56
1.5
1.8
—
—
—
0
0
6
37
1.63
0.56
1.0
1.1
—
—
—
0
0
20
151
1.35
0.55
2.8
6.2
1.52
1.31
mmol/l
0.18
15
144
9
132
0.67
0.53
1.4
1.6
—
—
—
0
0
6
40
1.51
0.52
3.7
2.1
137.17
130.04
g/l
—
6
26
9
65
1.40
0.51
1.3
2.1
—
—
—
0
0
51
440
1.19
0.50
1.6
1.4
21.82
20.96
nmol/l
0.20
44
383
22
172
1.30
0.50
3.6
2.4
324.31
3874.63
u/l
—
9
77
60
527
1.18
0.48
2.4
2.2
—
—
—
0
0
23
182
1.29
0.48
5.7
10.0
-0.29
1.33
mmol/l
0.79
17
141
34
283
1.23
0.48
2.0
1.6
—
—
—
0
0
56
492
1.17
0.45
2.8
2.4
7616.98
5311.35
umol/l
0.12
50
443
22
175
1.28
0.45
1.4
1.3
—
—
—
0
0
10
69
1.47
0.45
8.1
2.6
—
—
—
0
0
5
31
1.62
0.43
2.4
1.7
—
—
—
0
0
13
96
1.37
0.42
1.7
1.6
—
—
—
0
0
5
33
1.52
0.41
2.2
1.6
—
—
—
0
0
(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
0
16
0.00
0.41
0.0
1.2
—
—
—
0
0
0
16
0.00
0.41
0.0
3.4
—
—
—
0
0
0
17
0.00
0.41
0.0
1.1
—
—
—
0
0
8
61
1.32
0.40
1.3
1.3
2.30
3.51
ug/l
—
8
56
71
643
1.14
0.39
2.1
1.6
—
—
—
0
0
13
98
1.34
0.38
3.1
8.4
1.35
1.53
%
0.23
13
98
6
43
1.40
0.35
2.0
1.3
—
—
—
0
0
6
43
1.40
0.35
2.0
1.3
—
—
—
0
0
6
46
1.31
0.33
1.3
1.1
—
—
—
0
0
6
46
1.31
0.33
2.2
1.6
—
—
—
0
0
16
128
1.26
0.32
1.4
1.4
367.54
257.66
miu/ml
—
8
61
6
47
1.28
0.32
2.2
1.6
—
—
—
0
0
7
99
0.70
0.31
1.1
1.6
—
—
—
0
0
53
482
1.12
0.28
2.4
2.0
—
—
—
0
0
9
119
0.75
0.28
1.8
1.7
—
—
—
0
0
5
71
0.70
0.26
1.0
3.3
26.80
165.21
u/ml
—
5
61
233
2284
1.11
0.25
14.3
11.7
39.60
40.41
%
0.67
183
1856
12
96
1.26
0.25
3.1
8.6
89.51
94.22
%
0.45
12
96
55
508
1.10
0.23
2.0
1.9
—
—
—
0
0
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
0
10
0.00
0.21
0.0
1.7
—
—
—
0
0
0
10
0.00
0.21
0.0
1.7
—
—
—
0
0
0
10
0.00
0.21
0.0
1.7
—
—
—
0
0
0
10
0.00
0.21
0.0
1.8
—
—
—
0
0
0
10
0.00
0.21
0.0
1.7
—
—
—
0
0
8
105
0.76
0.21
4.4
5.7
24.35
24.83
mmol/l
—
8
105
0
13
0.00
0.21
0.0
1.2
—
—
—
0
0
9
111
0.80
0.20
1.1
1.6
—
—
—
0
0
6
52
1.16
0.19
1.0
1.5
3.68
3.65
mmol/l
—
6
46
25
224
1.13
0.17
2.5
2.6
0.59
0.71
ug/l
0.54
13
129
7
61
1.15
0.17
1.4
2.2
9.47
10.16
g/l
—
7
55
60
566
1.08
0.16
1.5
1.5
—
—
—
0
0
39
364
1.08
0.14
3.4
4.2
1.49
1.85
ug/l
0.67
33
324
10
117
0.85
0.13
1.3
1.4
—
—
—
0
0
18
164
1.10
0.10
1.0
1.0
—
—
—
0
0
5
45
1.11
0.10
1.0
1.2
—
—
—
0
0
11
97
1.14
0.09
3.5
8.5
0.65
0.71
%
0.13
11
97
6
54
1.11
0.09
1.0
1.6
14.33
148.40
e6/l
—
6
42
6
54
1.11
0.09
1.0
1.5
100.83
2.70
e6/l
—
6
40
8
75
1.07
0.07
1.4
1.5
—
—
—
0
0
20
214
0.93
0.07
1.3
1.3
254.59
179.38
iu/ml
—
8
86
10
90
1.12
0.05
1.1
1.3
—
—
—
0
0
13
141
0.92
0.05
2.6
2.1
13.68
13.17
nmol/l
0.05
13
131
16
152
1.06
0.02
3.5
2.4
68.40
74.47
ml/min/173m2
—
5
59
16
167
0.96
0.01
1.3
1.5
—
—
—
0
0
30
293
1.03
0.01
3.5
4.0
23.32
22.67
%
—
10
120
17
176
0.96
0.00
2.1
4.0
3.22
6.67
ug/l
1.08
12
135
27
264
1.03
0.00
1.7
2.4
4.61
8.32
umol/l
1.26
20
228
108
1086
0.99
0.00
3.5
4.0
—
—
—
0
0
14
138
1.02
0.00
7.0
7.4
8.11
7.94
mmol/l
0.06
14
131
28
281
1.00
0.00
1.3
1.5
—
—
—
0
0
11
113
0.97
0.00
1.6
2.0
—
—
—
0
0
22
217
1.01
0.00
2.5
2.4
29.88
29.24
u/l
0.08
17
181
16
155
1.03
0.00
1.3
1.4
—
—
—
0
0
15
155
0.97
0.00
1.3
1.4
—
—
—
0
0
15
155
0.97
0.00
1.3
1.4
—
—
—
0
0
16
155
1.03
0.00
1.3
1.4
—
—
—
0
0
18
185
0.97
0.00
2.6
2.8
—
—
—
0
0
0
6
0.00
0.00
0.0
1.5
—
—
—
0
0
0
8
0.00
0.00
0.0
1.4
—
—
—
0
0
0
9
0.00
0.00
0.0
1.7
—
—
—
0
0
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
9.13
—
0
5
0
9
0.00
0.00
0.0
1.7
—
—
—
0
0
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
0.00
0.0
1.3
—
—
—
0
0
6
61
0.98
0.00
1.2
1.2
—
—
—
0
0
0
7
0.00
0.00
0.0
2.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.3
—
—
—
0
0
0
6
0.00
0.00
0.0
1.3
—
—
—
0
0
0
7
0.00
0.00
0.0
1.3
—
—
—
0
0
0
7
0.00
0.00
0.0
2.0
—
—
—
0
0
5
49
1.02
0.00
1.0
1.8
—
—
—
0
0
5
56
0.89
0.00
1.0
1.5
—
—
—
0
0
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
0.00
0.0
1.5
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
2.0
—
—
—
0
0
0
9
0.00
0.00
0.0
1.7
—
—
—
0
0
0
9
0.00
0.00
0.0
1.7
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint L12_PITYROCHEA and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| L12_PITYROCHEA | 1.391 [0.95, 2.03] | 0.087 |
| Birth year | 0.995 [0.99, 1.0] | 0.267 |
During the follow-up period (1.1.1998 — 31.12.2019), 58 out of 1019 females with L12_PITYROCHEA died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| L12_PITYROCHEA | 1.467 [1.09, 1.98] | 0.013 |
| Birth year | 0.985 [0.97, 1.0] | 0.012 |
During the follow-up period (1.1.1998 — 31.12.2019), 67 out of 650 males with L12_PITYROCHEA died.
Mortality risk
Mortality risk for people of age
years, who have L12_PITYROCHEA.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.126% | 0.239% |
| 5 | 0.803% | 1.615% |
| 10 | 1.998% | 3.935% |
| 15 | 3.847% | 7.278% |
| 20 | 6.646% | 12.309% |
Relationships between endpoints
↥Index endpoint: L12_PITYROCHEA – Pityriasis rosea
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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