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Parapsoriasis

DOID EFO Endpoint Browser PheWeb

L12_PARAPSORI

parapsoriasis: one of a group of skin disorders that are characterized primarily by their resemblance to psoriasis (red, scaly lesions), rather than by their underlying etiology. Neoplasms can develop from parapsoriasis. For example, it can develop into cutaneous T-cell lymphoma.

Suggest a new description

Endpoint definition

↥

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — L41
  • Cause of death: ICD-10 — L41

2 out of 7 registries used, show all original rules.

381

4. Check minimum number of events

None

381

5. Include endpoints

702

6. Filter based on genotype QC (FinnGen only)

702

Control definitions (FinnGen only)

Control exclude
L12_PAPULOSQUAMOUS

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
L40-L45
Name in latin
Parapsoriasis

Case counts by codes

↥

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 5761 2864 2860
Only index persons 5168 2640 2528
Unadjusted period prevalence (%)
Whole population 0.08 0.08 0.08
Only index persons 0.10 0.10 0.10
Median age at first event (years)
Whole population 41.07 38.49 43.65
Only index persons 39.87 37.84 41.99

-FinnGen-

Key figures

All Female Male
Number of individuals 702 379 323
Unadjusted period prevalence (%) 0.14 0.13 0.14
Median age at first event (years) 47.34 40.92 54.87

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS (R11)

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
635
Matched controls
6348
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
L42
ICD-10 Finland
Pityriasis rosea
485.9
236.2
222
7
L41.1
ICD-10 Finland
Pityriasis lichenoides chronica
+∞
132.0
122
*
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
13.4
123.9
237
269
L41.9
ICD-10 Finland
Parapsoriasis, unspecified
+∞
85.4
80
*
D07AC01
ATC
betamethasone; topical
4.4
64.0
334
1284
L30.9
ICD-10 Finland
Dermatitis, unspecified
5.4
63.0
227
593
E0000UV
ATC
NA
4.2
62.5
374
1619
L41.3
ICD-10 Finland
Small plaque parapsoriasis
+∞
57.1
54
*
L41.8
ICD-10 Finland
Other parapsoriasis
+∞
56.1
53
*
L40.0
ICD-10 Finland
Psoriasis vulgaris
67.2
53.4
61
10
D07AB08
ATC
desonide; topical
6.2
51.9
156
318
L41.0
ICD-10 Finland
Pityriasis lichenoides et varioliformis acuta
+∞
47.5
45
*
D07AB02
ATC
hydrocortisone butyrate; topical
3.4
39.4
255
1054
L41.2
ICD-10 Finland
Lymphomatoid papulosis
+∞
37.9
36
*
E000001
ATC
NA
3.6
37.4
205
738
D07AC13
ATC
mometasone; topical
3.2
36.2
246
1039
WXQ27
NOMESCO Finland
UVB narrow spectrum light therapy
35.3
35.8
46
14
L41.4
ICD-10 Finland
Large plaque parapsoriasis
+∞
34.7
33
*
E000002
ATC
NA
4.1
29.9
131
382
C84.0
ICD-10 Finland
Mycosis fungoides
305.1
29.0
29
*
69630
ICD-8 Finland
Psoriasis and similar disorders, Pityriasis rosea
+∞
28.3
27
*
D07AD01
ATC
clobetasol; topical
3.7
26.9
133
427
D05BB02
ATC
acitretin; oral
25.0
22.4
31
13
XQ848
NOMESCO Finland
Dermatological photography
9.4
22.2
46
52
D07AA02
ATC
hydrocortisone; topical
3.1
21.5
132
492
D07BB04
ATC
hydrocortisone butyrate and antiseptics; topical
3.3
20.4
116
408
R21
ICD-10 Finland
Rash and other nonspecific skin eruption
5.7
19.7
58
110
L43.8
ICD-10 Finland
Other lichen planus
195.4
18.6
19
*
Z01.5
ICD-10 Finland
Diagnostic skin and sensitization tests
3.4
18.0
93
305
D05AX52
ATC
calcipotriol, combinations; topical
6.3
17.9
48
81
D01AC20
ATC
imidazoles/triazoles in combination with corticosteroids; topical
2.3
16.2
170
856
D07XC01
ATC
betamethasone, combinations; topical
3.1
16.1
94
334
H02AB06
ATC
prednisolone; systemic
2.0
14.7
306
2039
E000007
ATC
NA
4.0
14.2
57
151
D02AX
ATC
Other emollients and protectives
6.1
14.0
38
66
D05AX02
ATC
calcipotriol; topical
6.2
13.2
35
59
69621
ICD-8 Finland
Psoriasis and similar disorders, Parapsoriasis guttata
+∞
12.5
12
*
E000006
ATC
NA
3.5
12.1
58
179
L40.5
ICD-10 Finland
Arthropathic psoriasis
66.2
11.6
13
*
L41
ICD-10 Finland
Parapsoriasis
+∞
11.5
11
*
L20.0
ICD-10 Finland
Besnier prurigo
3.2
11.3
60
201
E000003
ATC
NA
4.0
11.2
44
115
TQW80
NOMESCO Finland
Local dermatologic skincare
6.0
11.2
30
52
L43.9
ICD-10 Finland
Lichen planus, unspecified
18.2
10.8
16
9
D02AE01
ATC
carbamide; topical
3.2
10.7
55
180
L40.9
ICD-10 Finland
Psoriasis, unspecified
19.2
10.3
15
8
D07BA04
ATC
hydrocortisone and antiseptics; topical
2.5
9.9
79
340
WXQ12
NOMESCO Finland
Psoralen - Ultraviolet A therapy with local sensitivisation
55.8
9.7
11
*
L04AX03
ATC
methotrexate; systemic (immunosuppressants)
2.8
9.5
62
236
M07.3*L40.5
ICD-10 Finland
Other psoriatic arthropathies
+∞
9.4
9
*
9700/3-C44.5
ICD-O-3
Mycosis fungoides of skin of trunk
+∞
9.4
9
*
L30.0
ICD-10 Finland
Nummular dermatitis
4.6
9.3
31
70
R06AE07
ATC
cetirizine; oral
1.7
8.9
270
1935
L43.0
ICD-10 Finland
Hypertrophic lichen planus
91.2
8.4
9
*
L40.4
ICD-10 Finland
Guttate psoriasis
91.2
8.4
9
*
9700/3-C44.9
ICD-O-3
Mycosis fungoides of skin, NOS
+∞
8.3
8
*
6961A
ICD-9 Finland
Psoriasis and similar disorders, Other psoriasis[PSORIASIS VULGARIS]
+∞
8.3
8
*
L20.9
ICD-10 Finland
Atopic dermatitis, unspecified
3.6
7.9
34
98
ZXC50
NOMESCO Finland
Cryotherapy
4.5
7.8
26
59
M25.5
ICD-10 Finland
Pain in joint
1.7
7.5
168
1091
D01AC02
ATC
miconazole; topical
2.5
7.5
56
234
L30.3
ICD-10 Finland
Infective dermatitis
4.0
7.4
28
72
D09AB01
ATC
zinc bandage without supplements; topical
6.1
7.4
19
32
R06AX27
ATC
desloratadine; oral
1.7
7.3
166
1080
A06AC01
ATC
ispaghula (psylla seeds); oral
1.8
7.3
142
879
69619
ICD-8 Finland
Psoriasis and similar disorders, Psoriasis alia sive NUD (vulgaris)
+∞
7.3
7
*
6963A
ICD-9 Finland
Psoriasis and similar disorders, Pityriasis rosea
+∞
7.3
7
*
WXQ10
NOMESCO Finland
Psoralen - Ultraviolet A therapy with systemic sensitivisation
+∞
7.3
7
*
J01DA01
ATC
[U] cefalexin; systemic
1.6
7.2
375
3030
D07BC01
ATC
betamethasone and antiseptics; topical
2.1
6.9
74
368
J01MA02
ATC
ciprofloxacin; systemic
1.6
6.8
221
1586
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.7
6.7
162
1071
QBA25
NOMESCO Finland
Destruction of lesion of skin of trunk
7.0
6.5
15
22
134
Kela drug reimbursment
General erythroderma
70.5
6.4
7
*
L40.8
ICD-10 Finland
Other psoriasis
70.5
6.4
7
*
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.6
6.4
208
1486
H04.10
ICD-10 Finland
Dry eye syndrome
2.2
6.4
62
297
XQ800
NOMESCO Finland
Prick test
2.3
6.4
56
254
D05AX03
ATC
calcitriol; topical
11.2
6.3
11
10
QXA05
NOMESCO Finland
Skin division, unspecified location
18.2
6.3
9
5
M07.0*L40.5
ICD-10 Finland
Distal interphalangeal psoriatic arthropathy
+∞
6.3
6
*
L26
ICD-10 Finland
Exfoliative dermatitis
+∞
6.3
6
*
XQ802
NOMESCO Finland
Epicutan test
3.2
6.2
30
96
J01DB01
ATC
cefalexin; oral
1.6
6.2
493
4334
L23.0
ICD-10 Finland
Allergic contact dermatitis due to metals
8.7
6.1
12
14

LabWAS

↥
OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
131
210
7.44
81.19
1.7
1.2
—
—
—
0
0
300
1799
2.17
21.39
7.3
5.5
—
—
—
0
0
415
2862
2.10
20.01
8.4
5.6
0.2
0.2
e9/l
1.24
390
2544
402
2766
2.06
19.18
8.2
5.4
0.0
0.0
e9/l
1.60
377
2410
400
2754
2.05
18.97
8.2
5.4
0.6
0.6
e9/l
2.28
376
2396
409
2848
2.04
18.69
8.3
5.4
2.0
1.9
e9/l
0.22
386
2540
371
2510
2.01
18.21
8.7
5.5
0.7
0.7
%
0.71
355
2348
381
2606
2.01
18.08
9.0
5.7
8.6
8.6
%
0.10
365
2450
390
2691
2.01
18.04
8.7
5.5
28.7
28.2
%
0.41
372
2516
378
2594
1.99
17.60
8.7
5.4
3.0
2.9
%
0.31
361
2422
384
2653
1.99
17.49
8.6
5.4
56.6
57.0
%
0.31
366
2491
441
3234
1.98
16.48
10.7
8.6
4.2
4.1
e9/l
0.33
413
2829
17
17
10.22
14.97
1.6
2.9
253.6
233.3
e6/l
—
11
6
348
2476
1.80
13.06
11.0
8.8
0.0
0.0
e9/l
0.23
297
2047
20
31
6.61
12.42
1.5
2.9
9.8
15.0
%
1.04
14
21
508
4117
1.85
11.69
5.4
3.7
11.4
11.3
mm/h
0.04
483
3814
22
42
5.38
11.12
2.0
1.2
—
—
—
0
0
19
32
6.07
10.91
1.5
2.0
—
39.4
—
0
5
198
1275
1.77
9.83
4.9
4.2
—
—
—
0
0
80
391
2.18
8.89
5.4
4.1
0.5
0.5
%
0.01
12
95
470
3874
1.65
8.58
4.9
4.0
—
—
—
0
0
21
49
4.39
8.45
1.6
2.4
1.6
1.2
e9/l
0.46
16
23
302
2245
1.61
8.41
5.1
4.8
35.5
35.8
g/l
0.54
284
2109
80
402
2.12
8.28
5.8
4.3
0.0
0.2
%
0.96
20
120
110
620
1.92
8.27
1.6
1.6
—
—
—
0
0
177
1159
1.70
8.08
1.5
1.5
2.4
2.4
g/l
0.20
119
722
168
1086
1.72
8.03
3.4
2.6
553.0
559.9
mosm/kgh2o
0.16
141
922
83
429
2.06
7.97
6.3
4.2
0.9
0.9
%
0.01
21
132
123
735
1.82
7.68
1.4
1.3
476.9
471.5
titre
0.02
26
155
499
4226
1.63
7.67
7.9
7.2
78.8
77.7
u/l
0.21
482
3979
74
381
2.05
7.18
6.7
4.4
0.0
0.1
%
0.66
13
101
84
458
1.95
6.94
1.6
1.4
—
—
—
0
0
145
934
1.70
6.93
1.3
1.3
19.5
37.1
iu/ml
1.92
44
293
580
5156
1.72
6.83
5.4
4.5
1.8
2.1
mu/l
0.56
543
4742
187
1292
1.61
6.78
1.4
1.3
1.2
1.4
u/ml
0.23
61
335
108
644
1.80
6.76
1.4
1.4
—
—
—
0
0
152
998
1.67
6.75
3.9
3.7
187.7
413.2
ng/l
1.08
108
743
288
2202
1.52
6.65
2.5
2.1
—
—
—
0
0
193
1375
1.56
6.05
7.6
6.3
—
—
—
0
0
110
682
1.73
6.00
2.2
2.5
104.5
123.7
ug/g
0.30
84
539
19
54
3.59
5.92
1.5
1.3
—
—
—
0
0
76
425
1.88
5.83
2.4
2.6
71.5
71.5
e9/l
0.00
60
328
36
150
2.48
5.80
3.2
3.1
—
—
—
0
0
67
360
1.95
5.79
1.7
1.2
624.2
214.2
u/ml
0.75
59
330
215
1583
1.52
5.76
2.2
2.1
172.0
310.3
u/l
1.22
207
1493
105
655
1.71
5.60
31.3
22.5
1.3
1.2
inr
0.13
14
98
493
4295
1.50
5.52
4.5
3.8
15.0
14.7
pmol/l
2.25
461
3910
344
2805
1.44
5.39
4.1
3.4
0.1
0.0
estimate
0.48
74
520
339
2758
1.44
5.37
4.0
3.4
0.0
0.0
estimate
0.00
76
532
617
5670
1.73
5.32
17.9
13.3
21.1
23.1
mg/l
0.80
503
4444
348
2852
1.44
5.27
5.4
6.2
11.0
11.2
umol/l
0.20
328
2704
16
44
3.70
5.23
1.6
2.4
987.3
506.2
e6/l
0.82
11
38
339
2775
1.43
5.11
5.5
4.6
0.0
0.0
estimate
0.50
76
538
141
969
1.57
5.10
3.2
2.8
2.5
2.4
mmol/l
1.81
127
851
93
578
1.70
5.02
2.5
2.6
1.8
1.8
%
0.09
83
527
187
1371
1.50
5.02
3.2
2.6
4280.0
7766.9
umol/l
0.56
163
1204
644
6014
1.86
4.95
12.6
9.6
25.9
26.6
u/l
0.53
629
5821
233
1794
1.45
4.84
3.5
3.3
2.4
2.3
mmol/l
0.07
206
1595
161
1152
1.52
4.84
3.0
2.4
3.5
6.3
e6/l
2.36
135
1006
71
413
1.80
4.82
2.4
3.1
66.6
66.8
g/l
0.09
66
378
131
897
1.57
4.80
1.3
1.3
10.4
12.6
u/ml
0.18
58
347
170
1233
1.50
4.78
2.1
1.8
1.3
1.2
mg/l
0.16
137
934
621
5753
1.69
4.73
19.0
15.1
139.3
139.6
mmol/l
2.60
611
5604
538
4831
1.49
4.67
21.5
16.1
13.7
13.6
%
0.42
526
4742
14
38
3.74
4.66
2.9
3.1
—
—
—
0
0
257
2032
1.42
4.57
4.0
3.6
37.4
55.2
ng/l
0.44
166
1373
124
848
1.56
4.56
3.5
3.2
0.8
0.8
mmol/l
0.34
114
802
41
205
2.06
4.36
1.3
1.2
0.2
2.5
u/ml
—
5
11
620
5773
1.63
4.23
19.3
15.2
4.0
4.0
mmol/l
0.21
609
5614
264
2121
1.39
4.20
10.5
8.4
1.3
1.2
inr
0.33
83
648
59
340
1.80
4.15
1.9
2.7
—
—
—
0
0
207
1604
1.41
4.04
4.0
3.9
8.5
9.3
mg/mmol
0.10
135
1033
214
1671
1.40
3.99
3.7
3.1
7.0
8.0
mmol/l
2.59
184
1408
64
385
1.73
3.90
2.7
2.8
184.5
165.3
ng/l
0.14
56
350
187
1432
1.42
3.88
4.2
4.2
—
—
—
0
0
220
1734
1.39
3.86
2.1
2.5
58.5
56.6
u/l
0.15
203
1611
11
29
3.84
3.81
1.7
1.9
—
—
—
0
0
39
202
1.99
3.80
1.9
1.6
—
—
—
0
0
106
730
1.53
3.77
1.2
1.2
—
—
—
0
0
314
2628
1.35
3.76
7.0
6.6
1.2
1.2
mmol/l
0.91
270
2223
202
1583
1.39
3.64
3.7
3.0
—
—
—
0
0
374
3225
1.34
3.62
5.7
4.8
6.6
6.6
mmol/l
0.19
351
2983
103
714
1.52
3.55
2.4
2.3
22.9
23.1
%
0.05
88
617
114
809
1.49
3.52
2.4
2.1
29.4
29.6
s
0.25
114
787
204
1612
1.37
3.47
3.5
2.9
—
—
—
0
0
243
1974
1.35
3.47
4.4
3.6
133.5
63.3
e6/l
0.37
185
1378
193
1513
1.38
3.45
3.2
3.2
47.2
302.4
mg/l
1.91
127
985
13
42
3.13
3.38
1.4
2.0
—
754.3
—
0
20
15
53
2.87
3.37
2.9
3.3
—
—
—
0
0
433
3838
1.33
3.37
4.1
3.6
—
—
—
0
0
174
1346
1.39
3.36
2.4
2.1
2.7
3.0
mg/l
0.80
153
1161
581
5396
1.45
3.36
4.4
4.3
5.9
5.9
mmol/l
0.19
541
4952
21
91
2.35
3.20
1.1
1.1
—
12.4
—
0
8
15
55
2.76
3.17
2.1
1.3
—
—
—
0
0
258
2139
1.33
3.15
2.2
1.9
94.4
94.7
pmol/l
0.03
163
1123
96
673
1.49
3.14
1.5
1.8
—
—
—
0
0
157
1212
1.38
3.05
1.8
1.9
—
—
—
0
0
183
1450
1.35
3.02
1.8
1.7
1.4
1.4
mmol/l
0.53
163
1222
75
504
1.55
2.99
3.7
4.0
1.3
2.1
mmol/l
0.78
61
398
207
1674
1.34
2.97
3.9
3.1
60.7
104.4
e6/l
0.47
174
1286
97
694
1.46
2.88
1.4
1.6
—
—
—
0
0
123
922
1.41
2.84
1.6
1.7
1128.3
1199.2
nmol/l
0.49
94
708
186
1495
1.33
2.76
4.4
3.7
0.0
0.0
estimate
0.88
75
527
18
78
2.34
2.76
1.7
1.5
—
—
—
0
0
588
5524
1.40
2.72
4.4
4.2
4.6
4.6
mmol/l
0.20
548
5157
64
427
1.55
2.66
1.3
1.5
—
—
—
0
0
74
511
1.50
2.63
2.9
2.0
291.1
378.3
nmol/l
3.56
68
476
157
1243
1.34
2.57
3.8
3.5
—
—
—
0
0
18
81
2.25
2.56
1.4
1.3
60.3
64.5
mmol/l
0.16
12
71
661
6367
1.65
2.55
26.1
19.4
7.0
6.7
e9/l
2.37
650
6198
103
763
1.41
2.54
1.9
2.1
—
—
—
0
0
584
5496
1.37
2.54
4.3
4.1
1.4
1.5
mmol/l
0.33
533
5102
94
686
1.43
2.52
4.4
5.5
1.0
1.0
mmol/l
0.82
85
639
181
1467
1.32
2.52
3.8
3.0
—
—
—
0
0
29
158
1.87
2.51
2.1
2.1
12.5
11.3
mg/l
0.26
23
150
294
2538
1.27
2.51
3.1
2.7
108.3
116.4
ug/l
0.28
287
2369
278
2386
1.27
2.49
6.4
5.9
1.2
1.2
mmol/l
0.52
257
2177
660
6360
1.63
2.48
26.1
19.4
255.6
250.5
e9/l
1.09
649
6210
84
603
1.45
2.46
1.3
1.3
—
—
—
0
0
128
989
1.36
2.46
1.5
1.7
—
—
—
0
0
660
6363
1.62
2.43
26.0
19.3
30.3
30.3
pg
0.54
654
6282
660
6363
1.62
2.43
26.0
19.3
91.0
90.7
fl
1.10
654
6283
660
6364
1.62
2.42
26.1
19.3
4.5
4.5
e12/l
0.34
650
6201
184
1504
1.30
2.40
3.9
3.0
0.3
0.4
e6/l
0.79
152
1124
5
8
6.28
2.37
1.6
2.1
—
—
—
0
0
660
6368
1.61
2.36
26.3
19.4
135.9
135.9
g/l
0.00
654
6282
593
5611
1.37
2.34
4.9
4.6
2.7
2.8
mmol/l
0.23
551
5204
177
1445
1.30
2.32
2.9
3.1
1326.1
1309.1
ng/l
0.02
150
1239
35
208
1.72
2.31
1.3
1.3
311.6
250.9
miu/ml
0.31
16
96
190
1567
1.29
2.31
4.1
3.9
7.4
7.4
ph
0.22
36
294
20
99
2.05
2.28
3.6
3.8
57.2
58.1
%
0.10
20
99
91
677
1.40
2.21
8.7
6.7
102.8
104.1
mmol/l
1.32
91
661
40
251
1.63
2.17
2.9
2.3
—
—
—
0
0
6
14
4.31
2.15
1.2
1.1
—
—
—
0
0
18
88
2.07
2.13
1.3
1.2
—
—
—
0
0
19
95
2.03
2.12
3.7
3.4
4.3
4.4
e9/l
0.09
19
95
25
139
1.83
2.07
3.4
4.3
—
—
—
0
0
15
69
2.20
2.05
1.9
2.6
—
—
—
0
0
23
125
1.87
2.05
1.7
1.6
7095.2
13502.3
e6/l
0.57
18
91
46
306
1.54
1.98
2.4
2.7
0.1
0.2
e6/l
1.11
46
295
17
84
2.05
1.97
1.6
1.1
—
—
—
0
0
7
21
3.36
1.97
1.0
1.1
1159.1
1682.9
miu/ml
—
7
21
539
5069
1.27
1.96
5.9
5.4
39.6
39.5
mmol/mol
0.07
515
4749
620
5954
1.35
1.82
16.3
12.4
—
—
—
0
0
40
264
1.55
1.80
4.1
4.5
23.7
24.3
mmol/l
0.56
34
244
148
1221
1.27
1.77
4.2
3.7
1.0
1.0
kg/l
1.44
27
166
165
1383
1.25
1.73
4.4
3.7
88.0
90.8
%
0.62
159
1353
155
1290
1.26
1.72
1.6
1.5
21.4
20.4
nmol/l
0.40
136
1097
65
482
1.38
1.65
4.6
3.5
—
—
—
0
0
51
364
1.43
1.60
3.8
3.8
82.0
78.2
ng/l
0.14
45
331
8
32
2.52
1.60
1.3
1.4
6.0
6.3
mmol/l
—
8
32
66
494
1.37
1.59
2.4
2.2
0.2
0.2
g/l
0.28
59
464
6
20
3.02
1.58
3.7
2.3
—
—
—
0
0
19
107
1.80
1.56
1.3
1.4
94.5
111.2
u/ml
—
6
21
6
22
2.74
1.43
1.2
1.7
1.3
0.9
nmol/l
—
6
16
28
181
1.57
1.42
1.3
1.2
—
—
—
0
0
52
382
1.39
1.42
2.9
2.4
4.5
4.2
e9/l
0.39
41
314
24
150
1.62
1.39
1.3
1.4
237.4
297.0
ug/g
1.00
11
88
106
871
1.26
1.33
3.4
2.9
4.1
2.1
e6/l
0.82
76
475
6
24
2.51
1.30
3.7
2.1
—
—
—
0
0
37
260
1.45
1.30
3.1
3.2
25.0
25.0
mmol/l
0.03
37
250
13
69
1.90
1.29
1.9
2.7
3.9
4.0
mmol/l
0.32
13
69
13
69
1.90
1.29
1.9
2.7
105.9
105.3
mmol/l
0.23
13
69
25
162
1.56
1.27
1.5
1.1
—
—
—
0
0
46
338
1.39
1.27
1.5
1.2
—
—
—
0
0
46
338
1.39
1.27
2.9
3.7
137.5
128.9
g/l
2.00
46
331
9
44
2.06
1.27
1.0
1.1
—
—
—
0
0
55
417
1.35
1.26
2.6
3.8
1.2
1.2
mmol/l
0.01
49
365
554
5307
1.21
1.25
3.9
3.7
1.3
1.3
mmol/l
0.80
501
4915
22
139
1.60
1.24
1.2
1.3
—
—
—
0
0
10
49
2.06
1.22
1.0
1.8
—
—
—
0
0
5
19
2.64
1.22
2.2
2.2
—
—
—
0
0
18
110
1.65
1.16
1.1
1.5
—
—
—
0
0
19
118
1.63
1.16
1.3
1.4
—
—
—
0
0
203
1804
1.18
1.15
4.8
4.8
1.8
2.4
ug/l
1.44
178
1618
79
640
1.26
1.13
1.5
1.5
—
—
—
0
0
14
80
1.77
1.13
3.5
3.0
0.6
0.9
nmol/l
—
9
60
86
704
1.25
1.13
1.5
1.3
—
—
—
0
0
35
251
1.42
1.13
3.9
3.2
—
—
—
0
0
7
30
2.35
1.12
1.0
1.1
118.6
179.2
iu/ml
—
7
30
8
40
2.01
1.12
1.0
1.2
26.5
46.5
mg/l
—
8
31
5
21
2.39
1.09
1.6
2.2
—
—
—
0
0
5
21
2.39
1.09
1.0
1.5
—
—
—
0
0
23
153
1.52
1.07
2.3
1.8
2.0
6.2
iu/l
—
7
51
13
74
1.77
1.07
2.6
2.7
—
—
—
0
0
19
122
1.57
1.03
1.4
1.2
257.8
219.3
u/ml
0.31
12
64
129
1115
1.19
1.01
1.8
1.7
467.8
16951385.4
pmol/l
1.04
109
938
12
68
1.78
1.01
2.0
2.8
—
—
—
0
0
5
23
2.18
0.98
1.0
1.3
—
—
—
0
0
41
311
1.34
0.97
1.4
1.2
—
—
—
0
0
123
1063
1.19
0.97
3.0
2.9
0.6
0.8
ug/l
1.73
71
683
9
50
1.81
0.97
1.0
1.7
—
—
—
0
0
11
62
1.79
0.94
1.2
1.2
—
—
—
0
0
12
70
1.73
0.93
1.2
1.4
—
—
—
0
0
64
520
1.25
0.92
2.5
2.6
29.8
125.8
u/l
0.52
51
437
6
28
2.15
0.91
1.2
1.0
—
0.3
u/ml
—
0
5
57
458
1.27
0.90
1.2
1.2
—
—
—
0
0
13
79
1.66
0.88
1.2
1.2
—
—
—
0
0
6
30
2.01
0.87
1.2
1.8
—
—
—
0
0
11
64
1.73
0.86
1.2
1.4
—
—
nmol/l
—
0
0
12
72
1.68
0.85
1.0
1.2
—
—
—
0
0
17
112
1.53
0.85
2.8
1.5
—
—
—
0
0
15
96
1.57
0.85
1.1
1.1
1.6
5.7
u/ml
—
5
21
512
4929
1.14
0.84
23.4
16.8
332.9
333.0
g/l
0.05
507
4894
6
31
1.94
0.84
1.2
1.3
—
—
—
0
0
8
46
1.75
0.82
1.0
1.2
—
—
—
0
0
6
32
1.88
0.82
1.2
1.7
—
—
—
0
0
8
47
1.71
0.81
1.0
1.4
—
—
—
0
0
15
98
1.54
0.79
3.4
2.0
14.4
16.1
%
—
9
48
15
98
1.54
0.79
5.7
3.2
—
—
—
0
0
55
449
1.24
0.78
11.1
8.0
—
—
—
0
0
14
90
1.57
0.78
1.1
1.0
—
—
—
0
0
14
90
1.57
0.78
2.9
2.7
—
—
—
0
0
16
107
1.51
0.76
1.1
1.2
—
—
—
0
0
43
342
1.27
0.76
3.7
2.3
—
—
—
0
0
6
34
1.77
0.76
1.0
1.1
—
—
—
0
0
35
271
1.31
0.76
12.5
9.3
24.0
24.5
mmol/l
0.30
29
258
12
75
1.61
0.75
1.0
1.1
5.5
3.5
u/ml
—
7
28
31
237
1.32
0.73
1.1
1.1
—
—
—
0
0
51
417
1.24
0.73
2.4
2.5
5.5
7.4
ug/l
0.55
42
372
14
92
1.53
0.72
3.3
2.0
—
—
—
0
0
7
39
1.80
0.72
1.3
1.0
—
—
—
0
0
7
39
1.80
0.72
1.0
1.1
158.1
240.0
mg/l
—
7
33
5
26
1.93
0.70
1.0
4.8
63.8
93.4
nmol/l
—
5
26
7
41
1.71
0.70
1.0
1.4
—
—
—
0
0
5
27
1.86
0.68
1.0
1.4
—
—
—
0
0
24
179
1.35
0.67
5.2
1.7
—
—
—
0
0
43
350
1.24
0.65
3.4
3.2
7.4
7.4
ph
—
8
35
5
29
1.73
0.64
1.0
1.0
—
—
—
0
0
10
63
1.60
0.62
2.2
1.3
—
—
—
0
0
5
30
1.67
0.61
1.0
1.1
—
—
—
0
0
541
5266
1.12
0.60
20.4
14.0
39.8
40.1
%
0.28
399
3946
68
586
1.18
0.60
7.9
8.0
5.0
5.1
kpa
0.33
63
564
0
22
0.00
0.59
0.0
1.4
—
—
—
0
0
68
587
1.18
0.59
7.8
8.0
11.5
12.2
kpa
0.93
63
568
166
1525
1.12
0.59
4.1
3.7
—
—
—
0
0
13
89
1.47
0.58
3.3
1.3
—
—
—
0
0
19
141
1.36
0.57
1.1
1.5
567.3
480.7
mg/l
0.28
19
132
32
257
1.26
0.56
2.9
2.2
11591.9
4210.2
u/l
0.27
11
110
13
90
1.45
0.55
1.5
1.6
—
—
—
0
0
282
2671
1.09
0.54
4.9
4.1
—
—
—
0
0
9
61
1.48
0.54
2.0
1.6
87.9
90.4
%
—
9
61
78
689
1.15
0.52
1.6
1.7
—
—
—
0
0
28
226
1.25
0.48
2.3
1.6
—
—
—
0
0
33
273
1.22
0.47
14.8
10.7
—
—
—
0
0
62
544
1.15
0.46
2.4
4.3
112.2
28.3
ug/l
0.42
45
456
13
94
1.39
0.46
1.5
1.7
—
—
—
0
0
11
77
1.44
0.45
3.6
3.3
0.8
1.2
%
—
6
62
55
480
1.16
0.44
3.9
4.1
—
—
—
0
0
7
51
1.38
0.44
1.3
1.1
—
—
—
0
0
159
1703
0.91
0.44
1.3
1.5
—
—
—
0
0
190
1785
1.09
0.44
3.4
2.3
—
—
—
0
0
5
31
1.62
0.43
1.4
4.4
—
—
—
0
0
8
56
1.43
0.42
1.1
1.7
—
—
—
0
0
5
32
1.57
0.42
1.0
1.2
—
—
—
0
0
5
32
1.57
0.42
1.0
1.1
—
—
—
0
0
66
587
1.14
0.42
9.1
8.0
1.0
1.1
mmol/l
0.09
51
470
47
408
1.16
0.41
1.2
1.2
128.1
151.5
iu/ml
0.15
22
165
5
33
1.52
0.41
1.0
1.5
0.8
1.0
g/l
—
5
33
71
636
1.13
0.41
2.4
2.7
7.3
8.6
umol/l
0.27
57
554
5
34
1.47
0.40
1.6
1.3
—
—
—
0
0
8
61
1.32
0.39
1.1
1.1
—
—
—
0
0
5
35
1.43
0.39
1.0
1.2
—
—
—
0
0
9
66
1.37
0.38
1.4
1.5
—
—
—
0
0
9
66
1.37
0.38
1.4
1.5
—
—
—
0
0
9
66
1.37
0.38
1.4
1.5
—
—
—
0
0
9
66
1.37
0.38
1.4
1.5
—
—
—
0
0
15
116
1.30
0.37
3.8
4.3
—
—
—
0
0
8
116
0.69
0.37
2.1
1.2
—
—
—
0
0
5
77
0.65
0.36
5.0
6.2
10.8
11.4
mg/l
—
5
70
47
414
1.14
0.35
4.1
3.4
—
—
—
0
0
9
126
0.71
0.35
1.4
1.3
—
—
—
0
0
12
91
1.32
0.34
1.3
1.3
5.3
4.6
u/ml
—
6
37
14
109
1.29
0.33
1.1
1.8
—
—
—
0
0
13
101
1.29
0.32
1.2
1.1
—
—
—
0
0
62
564
1.11
0.30
1.5
1.4
—
—
—
0
0
23
270
0.85
0.29
1.1
1.1
—
—
—
0
0
7
57
1.23
0.29
1.0
1.2
—
—
—
0
0
8
63
1.27
0.28
1.3
1.1
—
—
—
0
0
8
63
1.27
0.28
1.1
1.7
13.3
16.0
ug/l
—
8
63
23
196
1.18
0.27
3.0
4.6
—
—
—
0
0
24
206
1.17
0.26
2.5
1.3
—
—
—
0
0
140
1329
1.07
0.26
3.0
2.3
—
—
—
0
0
5
72
0.69
0.26
1.8
2.6
—
—
—
0
0
24
208
1.16
0.24
5.1
3.3
0.3
0.2
g/l
0.19
15
90
57
619
0.91
0.24
1.3
1.3
—
—
—
0
0
14
115
1.22
0.23
1.1
1.1
1.5
3.5
u/ml
—
9
47
5
41
1.22
0.22
1.0
1.2
—
—
—
0
0
0
10
0.00
0.21
0.0
1.4
—
—
—
0
0
0
10
0.00
0.21
0.0
1.2
—
1.8
—
0
10
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
12
98
1.23
0.21
1.5
1.3
—
—
—
0
0
0
12
0.00
0.21
0.0
10.3
—
—
—
0
0
8
105
0.76
0.21
1.0
1.2
—
—
—
0
0
10
122
0.82
0.19
2.6
4.2
12.2
23.7
mg/l
—
5
82
52
483
1.08
0.18
9.9
6.9
1.3
1.3
mmol/l
0.03
47
460
35
320
1.10
0.17
6.0
8.2
25.3
24.4
mmol/l
0.63
30
302
41
378
1.09
0.17
1.4
1.4
—
—
—
0
0
7
62
1.13
0.17
1.1
1.0
—
—
—
0
0
6
77
0.78
0.15
1.7
1.9
—
—
—
0
0
6
77
0.78
0.15
1.2
1.1
1.5
1.4
g/l
—
6
71
20
221
0.90
0.13
3.4
2.7
—
—
—
0
0
15
168
0.89
0.11
1.5
1.4
—
—
—
0
0
26
240
1.09
0.11
2.4
1.4
—
—
—
0
0
14
156
0.90
0.10
3.6
3.9
3.7
3.9
mmol/l
1.40
14
143
24
222
1.08
0.10
1.6
1.2
—
—
—
0
0
12
106
1.13
0.10
3.5
1.8
—
—
—
0
0
40
380
1.06
0.09
1.1
1.4
—
—
—
0
0
35
332
1.06
0.08
4.7
5.9
—
—
—
0
0
15
163
0.92
0.07
1.5
1.4
—
—
—
0
0
15
163
0.92
0.07
1.5
1.4
—
—
—
0
0
28
265
1.06
0.07
3.0
3.3
—
—
—
0
0
9
100
0.90
0.06
1.0
1.1
—
—
—
0
0
9
100
0.90
0.06
1.0
1.1
—
—
—
0
0
12
129
0.93
0.03
1.0
1.1
—
—
—
0
0
25
259
0.96
0.02
2.4
1.4
—
—
—
0
0
17
163
1.04
0.01
1.6
1.7
54.4
40.5
nmol/l
0.66
17
156
210
2092
1.01
0.01
2.5
2.7
—
—
—
0
0
12
117
1.03
0.00
2.2
4.5
—
—
—
0
0
13
127
1.02
0.00
2.4
3.4
31.6
35.3
umol/l
0.22
13
109
32
317
1.01
0.00
1.8
1.7
—
—
—
0
0
18
182
0.99
0.00
9.8
10.4
—
—
—
0
0
26
261
1.00
0.00
2.8
1.4
—
—
—
0
0
26
261
1.00
0.00
2.4
1.4
—
—
—
0
0
0
8
0.00
0.00
0.0
1.1
—
41.8
—
0
8
26
260
1.00
0.00
2.4
1.4
—
—
—
0
0
0
5
0.00
0.00
0.0
3.4
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
5
59
0.85
0.00
1.6
3.7
—
—
—
0
0
0
5
0.00
0.00
0.0
2.4
—
190.4
—
0
5
6
59
1.02
0.00
1.5
2.4
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
72.7
—
0
5
0
7
0.00
0.00
0.0
1.1
—
15.6
—
0
7
0
5
0.00
0.00
0.0
1.4
—
105.2
—
0
5
0
9
0.00
0.00
0.0
11.4
—
—
—
0
0
12
120
1.00
0.00
1.4
1.7
—
—
—
0
0
7
78
0.90
0.00
1.4
2.3
2.7
57.5
u/ml
—
7
72
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
5
59
0.85
0.00
5.6
6.9
7.3
6.9
mmol/l
—
5
44
0
8
0.00
0.00
0.0
1.4
—
—
—
0
0
0
8
0.00
0.00
0.0
1.3
—
—
—
0
0
5
56
0.89
0.00
2.4
2.6
—
—
—
0
0
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
0.00
0.0
7.0
—
—
—
0
0
6
63
0.95
0.00
1.8
2.4
—
—
—
0
0

Mortality – FinRegistry

↥

Association

Association between endpoint L12_PARAPSORI and mortality.

Females

Parameter HR [95% CI] p-value
L12_PARAPSORI 1.115 [0.94, 1.32] 0.2
Birth year 0.997 [0.99, 1.01] 0.585

During the follow-up period (1.1.1998 — 31.12.2019), 221 out of 2204 females with L12_PARAPSORI died.

Males

Parameter HR [95% CI] p-value
L12_PARAPSORI 0.996 [0.87, 1.14] 0.949
Birth year 0.988 [0.98, 1.0] 0.026

During the follow-up period (1.1.1998 — 31.12.2019), 354 out of 2069 males with L12_PARAPSORI died.

Mortality risk

Mortality risk for people of age

years, who have L12_PARAPSORI.

N-year risk Females Males
1 0.097% 0.203%
5 0.617% 1.12%
10 1.461% 2.943%
15 2.779% 5.843%
20 5.352% 10.016%

Relationships between endpoints

↥

Index endpoint: L12_PARAPSORI – Parapsoriasis

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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