Parapsoriasis

L12_PARAPSORI

parapsoriasis: one of a group of skin disorders that are characterized primarily by their resemblance to psoriasis (red, scaly lesions), rather than by their underlying etiology. Neoplasms can develop from parapsoriasis. For example, it can develop into cutaneous T-cell lymphoma.

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Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

519972

1. Apply sex-specific rule

None

519972

2. Check conditions

None

519972

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 L41
  • Cause of death: ICD-10 L41

2 out of 7 registries used, show all original rules.

395

4. Check minimum number of events

None

395

5. Include endpoints

727

6. Filter based on genotype QC (FinnGen only)

701

Control definitions (FinnGen only)

Control exclude
L12_PAPULOSQUAMOUS

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
L40-L45
Name in latin
Parapsoriasis

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 5761 2864 2860
Only index persons 5168 2640 2528
Unadjusted period prevalence (%)
Whole population 0.08 0.08 0.08
Only index persons 0.10 0.10 0.10
Median age at first event (years)
Whole population 41.07 38.49 43.65
Only index persons 39.87 37.84 41.99

-FinnGen-

Key figures

All Female Male
Number of individuals 701 382 319
Unadjusted period prevalence (%) 0.14 0.14 0.15
Median age at first event (years) 48.24 42.05 55.66

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
727
Matched controls
7270
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
L42
ICD-10 Finland
Pityriasis rosea
307.1
307.7
258
13
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
13.1
229.9
271
315
L41.1
ICD-10 Finland
Pityriasis lichenoides chronica
+∞
150.4
139
*
L40.0
ICD-10 Finland
Psoriasis vulgaris
39.2
114.5
71
20
L30.9
ICD-10 Finland
Dermatitis, unspecified
5.3
101.9
290
804
L41.9
ICD-10 Finland
Parapsoriasis, unspecified
+∞
100.4
94
*
WXQ27
NOMESCO Finland
UVB narrow spectrum light therapy
36.2
94.9
60
18
D07AC01
ATC
betamethasone; topical
4.5
87.8
408
1620
E0000UV, ,
ATC
4.2
77.9
452
2052
D07AB08
ATC
desonide; topical
5.1
70.9
179
436
L41.3
ICD-10 Finland
Small plaque parapsoriasis
+∞
62.4
59
*
L41.8
ICD-10 Finland
Other parapsoriasis
+∞
61.3
58
*
E000001, ,
ATC
3.6
52.9
233
839
L41.0
ICD-10 Finland
Pityriasis lichenoides et varioliformis acuta
+∞
51.7
49
*
D05BB02
ATC
acitretin; oral
20.5
50.5
39
20
D07AB02
ATC
hydrocortisone butyrate; topical
3.1
45.7
303
1376
D05AX52
ATC
calcipotriol, combinations; topical
8.2
44.8
62
82
D07AC13
ATC
mometasone; topical
3.0
44.0
285
1273
L41.4
ICD-10 Finland
Large plaque parapsoriasis
+∞
43.2
41
*
E000002, ,
ATC
3.9
42.1
146
442
L41.2
ICD-10 Finland
Lymphomatoid papulosis
+∞
42.1
40
*
D07AD01
ATC
clobetasol; topical
3.5
41.2
170
578
XQ848
NOMESCO Finland
Dermatological photography
7.5
39.1
58
83
R21
ICD-10 Finland
Rash and other nonspecific skin eruption
5.7
36.8
72
137
D05AX02
ATC
calcipotriol; topical
10.1
36.2
42
44
69630
ICD-8 Finland
Psoriasis and similar disorders, Pityriasis rosea
+∞
32.5
31
*
C84.0
ICD-10 Finland
Mycosis fungoides
86.4
30.0
33
*
D07BB04
ATC
hydrocortisone butyrate and antiseptics; topical
3.0
27.2
137
516
Z01.5
ICD-10 Finland
Diagnostic skin and sensitization tests
3.5
27.2
105
337
D07XC01
ATC
betamethasone; topical
3.4
26.8
110
367
D07AA02
ATC
hydrocortisone; topical
2.8
26.0
152
620
TQW80
NOMESCO Finland
Local dermatologic skincare
7.0
25.3
39
58
H02AB06
ATC
prednisolone; systemic
2.1
21.5
369
2383
D01AC20
ATC
imidazoles/triazoles in combination with corticosteroids; topical
2.3
20.2
190
962
L43.8
ICD-10 Finland
Other lichen planus
59.3
20.0
23
*
L04AX03
ATC
methotrexate; systemic
3.1
18.3
81
281
D02AX
ATC
Other emollients and protectives
4.6
18.0
44
101
E000006, ,
ATC
3.2
16.0
65
214
D07BA04
ATC
hydrocortisone and antiseptics; topical
2.7
15.9
92
369
L40.5
ICD-10 Finland
Arthropathic psoriasis
+∞
15.7
15
*
E000007, ,
ATC
3.3
15.5
61
197
E000003, ,
ATC
3.9
15.0
45
121
R06AE07
ATC
cetirizine; oral
1.9
14.6
326
2212
XQ845
NOMESCO Finland
Dermatoscopy
6.2
13.9
24
40
D02AE01
ATC
carbamide; topical
3.1
13.8
60
205
69621
ICD-8 Finland
Psoriasis and similar disorders, Parapsoriasis guttata
+∞
13.6
13
*
L40.9
ICD-10 Finland
Psoriasis, unspecified
18.7
13.4
20
11
D09AB01
ATC
zinc bandage without supplements; topical
6.5
13.3
22
35
L43.9
ICD-10 Finland
Lichen planus, unspecified
15.4
13.2
21
14
ZXC50
NOMESCO Finland
Cryotherapy
4.4
12.8
32
75
R06AX27
ATC
desloratadine; oral
1.9
12.2
218
1363
L20.9
ICD-10 Finland
Atopic dermatitis, unspecified
3.5
12.2
42
124
L30.0
ICD-10 Finland
Nummular dermatitis
3.6
11.5
39
114
L41
ICD-10 Finland
Parapsoriasis
+∞
11.5
11
*
D07BC01
ATC
betamethasone and antiseptics; topical
2.3
11.3
91
425
L30.3
ICD-10 Finland
Infective dermatitis
3.6
10.6
35
101
L43.0
ICD-10 Finland
Hypertrophic lichen planus
111.6
10.4
11
*
9700/3-C44.9
ICD-O-3
Mycosis fungoides of skin, NOS
111.6
10.4
11
*
M07.3*L40.5
ICD-10 Finland
Other psoriatic arthropathies
33.0
10.4
13
*
L20.0
ICD-10 Finland
Besnier prurigo
2.5
10.3
69
296
J01FF01
ATC
clindamycin; systemic
1.8
9.9
193
1229
XQ800
NOMESCO Finland
Prick test
2.5
9.6
62
262
WXQ10
NOMESCO Finland
Psoralen - Ultraviolet A therapy with systemic sensitivisation
+∞
9.4
9
*
QAA25
NOMESCO Finland
Destruction of lesion of head or neck
4.1
9.3
25
62
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
1.6
9.3
352
2664
J01DB01
ATC
cefalexin; oral
1.8
9.1
588
5083
D01AC02
ATC
miconazole; topical
2.4
9.0
62
270
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.6
8.9
257
1813
L40.4
ICD-10 Finland
Guttate psoriasis
50.6
8.7
10
*
9700/3-C44.5
ICD-O-3
Mycosis fungoides of skin of trunk
91.1
8.4
9
*
69619
ICD-8 Finland
Psoriasis and similar disorders, Psoriasis alia sive NUD (vulgaris)
+∞
8.3
8
*
6961A
ICD-9 Finland
Psoriasis and similar disorders, Other psoriasis[PSORIASIS VULGARIS]
+∞
8.3
8
*
6963A
ICD-9 Finland
Psoriasis and similar disorders, Pityriasis rosea
+∞
8.3
8
*
WXQ12
NOMESCO Finland
Psoralen - Ultraviolet A therapy with local sensitivisation
17.4
8.1
12
7
L04AD01
ATC
ciclosporin; systemic
6.2
7.9
20
33
J01MA02
ATC
ciprofloxacin; systemic
1.6
7.8
261
1893
L04AA01
ATC
[U] ciclosporin
8.2
7.6
16
20
QXA05
NOMESCO Finland
Skin division, unspecified location
18.6
7.6
11
6
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
1.9
7.6
96
532
L57.0
ICD-10 Finland
Actinic keratosis
2.1
7.5
72
361
XQ802
NOMESCO Finland
Epicutan test
2.9
7.4
34
121
QBE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin of trunk
2.4
7.3
52
230
M07.0*L40.5
ICD-10 Finland
Distal interphalangeal psoriatic arthropathy
+∞
7.3
7
*
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.6
7.3
189
1288
D05AX03
ATC
calcitriol; topical
15.9
7.2
11
7
Z3231
NOMESCO Finland
Registered nurse
1.6
7.2
191
1309
134
Kela drug reimbursment
General erythroderma
30.3
7.2
9
*
D07AB01
ATC
clobetasone; topical
3.3
7.0
26
81
J01DA01
ATC
[U] cefalexin
1.5
6.9
419
3436
A06AC01
ATC
ispaghula (psylla seeds); oral
1.6
6.9
172
1158
R51
ICD-10 Finland
Headache
2.5
6.8
44
186
S18
ICPC
Laceration/cut
1.5
6.8
304
2336
L50.8
ICD-10 Finland
Other urticaria
4.3
6.8
17
40
S99
ICPC
Skin disease other
4.0
6.7
19
49
L40.8
ICD-10 Finland
Other psoriasis
22.7
6.7
9
*
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
2.1
6.7
62
307
M25.5
ICD-10 Finland
Pain in joint
1.6
6.6
215
1542
L26
ICD-10 Finland
Exfoliative dermatitis
70.4
6.4
7
*
M07.3
ICD-10 Finland
Other psoriatic arthropathies
70.4
6.4
7
*
XF404
NOMESCO Finland
Ambulatory ECG
2.0
6.3
64
327
R2130
NOMESCO Finland
Counselling and guidance which enhance independent living
2.1
6.3
60
300
69623
ICD-8 Finland
Psoriasis and similar disorders, Parapsoriasis varioliformis
+∞
6.3
6
*
Z71.8
ICD-10 Finland
Other specified counselling
1.5
6.2
213
1540
ZY020
NOMESCO Finland
Telephone, letter or other consultation without direct patient contact
2.2
6.2
50
234
QAA05
NOMESCO Finland
Incision for biopsy of skin of head or neck
3.7
6.1
19
53

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
139
216
7.72
88.80
1.6
1.2
—
—
—
0
0
412
2699
2.22
24.00
8.2
5.8
—
—
—
0
0
433
2977
2.12
21.24
8.5
5.6
0.21
0.19
e9/l
1.39
406
2645
419
2879
2.07
20.17
8.3
5.3
0.04
0.04
e9/l
1.75
392
2513
418
2873
2.07
20.07
8.3
5.3
0.60
0.57
e9/l
1.91
392
2502
427
2969
2.06
19.72
8.4
5.4
1.95
1.94
e9/l
0.10
404
2665
385
2613
2.01
18.63
8.9
5.5
0.71
0.67
%
0.91
368
2444
406
2814
2.00
18.43
8.9
5.5
28.72
28.26
%
0.36
389
2649
395
2725
1.98
18.02
9.2
5.7
8.58
8.53
%
0.13
378
2560
399
2773
1.97
17.70
8.8
5.3
56.63
56.94
%
0.20
382
2609
460
3358
2.01
17.69
10.7
8.6
4.14
4.09
e9/l
0.20
430
2938
392
2712
1.97
17.58
8.9
5.4
2.97
2.85
%
0.37
375
2542
363
2572
1.82
13.94
11.2
8.8
0.00
0.00
e9/l
0.24
310
2121
526
4281
1.83
11.69
5.5
3.7
11.28
11.40
mm/h
0.07
500
3964
22
43
5.24
10.84
2.0
1.2
—
—
—
0
0
84
406
2.21
9.58
5.7
4.1
0.40
0.65
%
0.72
26
141
85
417
2.18
9.34
6.2
4.3
0.04
0.14
%
1.09
25
137
490
4033
1.66
9.10
4.9
4.0
—
—
—
0
0
88
444
2.12
9.00
6.7
4.2
0.75
1.04
%
0.68
28
165
115
642
1.94
8.89
1.6
1.6
—
—
—
0
0
187
1213
1.73
8.87
1.5
1.5
2.41
2.38
g/l
0.09
127
754
17
18
9.64
8.81
1.6
2.9
253.64
221.43
e6/l
—
11
7
80
395
2.15
8.64
7.0
4.3
0.20
0.11
%
0.16
20
115
21
49
4.38
8.45
1.6
2.4
1.60
1.26
e9/l
0.45
16
43
129
763
1.84
8.33
1.4
1.3
465.71
463.70
titre
0.01
28
162
312
2337
1.59
8.29
5.2
4.9
35.53
35.84
g/l
0.50
293
2198
178
1160
1.71
8.23
3.5
2.7
547.29
553.51
mosm/kgh2o
0.15
150
990
519
4386
1.64
8.17
8.0
7.2
78.41
77.86
u/l
0.10
501
4134
160
1023
1.72
7.90
3.9
3.7
181.48
409.83
ng/l
1.14
112
759
73
363
2.12
7.75
1.6
1.2
579.55
214.79
u/ml
0.71
64
332
606
5374
1.77
7.52
5.3
4.5
1.84
2.10
mu/l
0.58
568
4946
88
475
1.97
7.48
1.6
1.4
—
—
—
0
0
151
966
1.71
7.40
1.3
1.3
19.36
37.28
iu/ml
2.09
45
308
23
64
3.68
7.35
1.9
1.9
—
—
—
0
0
112
659
1.83
7.32
1.5
1.4
—
—
—
0
0
300
2275
1.54
7.29
2.5
2.1
—
—
—
0
0
118
711
1.79
7.12
2.4
2.4
110.10
121.63
ug/g
0.17
89
565
19
34
5.71
7.10
1.5
2.0
42.65
36.86
%
0.68
19
34
196
1358
1.61
7.01
1.4
1.3
1.18
1.34
u/ml
0.16
62
349
226
1636
1.55
6.64
2.2
2.1
199.91
305.33
u/l
0.76
217
1543
362
2906
1.49
6.46
4.1
3.4
0.05
0.01
estimate
0.47
80
541
358
2871
1.49
6.40
4.0
3.4
0.00
0.00
estimate
0.50
87
592
201
1430
1.56
6.34
7.5
6.4
—
—
—
0
0
357
2876
1.47
6.15
5.5
4.6
0.00
0.00
estimate
0.50
82
562
515
4475
1.52
5.99
4.4
3.8
14.97
14.68
pmol/l
1.88
481
4070
19
54
3.59
5.91
1.5
1.3
—
—
—
0
0
78
438
1.87
5.89
2.4
2.6
71.37
71.70
e9/l
0.03
61
336
297
2335
1.46
5.66
2.5
2.3
78.42
75.55
nmol/l
0.93
277
2104
641
5886
1.75
5.66
17.9
13.3
21.07
22.98
mg/l
0.78
524
4608
76
430
1.86
5.61
2.4
3.2
66.63
66.83
g/l
0.08
71
394
180
1283
1.54
5.54
2.1
1.8
1.28
1.16
mg/l
0.14
147
969
317
2533
1.45
5.51
19.9
13.4
1.25
1.23
inr
0.11
104
779
362
2966
1.44
5.48
5.4
6.3
10.96
11.27
umol/l
0.32
341
2815
36
155
2.39
5.42
3.1
3.0
—
—
—
0
0
97
598
1.72
5.38
2.5
2.6
1.80
1.79
%
0.02
87
545
577
5184
1.55
5.32
21.3
15.8
14.58
14.74
%
0.30
566
5105
169
1200
1.53
5.27
3.0
2.4
4.26
6.35
e6/l
1.37
143
1076
668
6234
1.88
5.23
12.7
9.6
25.77
26.45
u/l
0.55
652
6033
137
929
1.58
5.23
1.3
1.3
9.90
12.54
u/ml
0.23
61
354
16
44
3.70
5.23
1.6
2.4
987.27
497.08
e6/l
0.84
11
38
44
210
2.17
5.22
1.3
1.2
0.22
2.76
u/ml
—
5
10
194
1423
1.50
5.17
3.2
2.7
4114.76
7734.86
umol/l
0.62
170
1260
146
1011
1.56
5.08
3.2
2.9
2.46
2.44
mmol/l
1.34
132
887
645
5970
1.71
5.04
19.2
15.2
139.31
139.65
mmol/l
2.61
635
5815
268
2108
1.43
4.93
3.9
3.6
36.42
56.56
ng/l
0.54
173
1430
240
1859
1.43
4.78
3.5
3.4
2.35
2.35
mmol/l
0.05
215
1662
63
354
1.85
4.77
1.9
2.8
—
—
—
0
0
644
5991
1.66
4.52
19.5
15.3
3.96
3.96
mmol/l
0.24
633
5826
232
1803
1.42
4.48
2.3
2.5
58.16
60.41
u/l
0.16
215
1679
393
3342
1.38
4.44
5.9
4.8
6.56
6.62
mmol/l
0.26
369
3093
128
888
1.54
4.39
3.6
3.4
0.81
0.82
mmol/l
0.09
119
844
212
1638
1.42
4.19
3.7
3.0
—
—
—
0
0
453
3967
1.38
4.13
4.1
3.6
—
—
—
0
0
41
210
2.01
4.10
1.9
1.7
—
—
—
0
0
111
761
1.54
4.01
1.2
1.2
—
—
—
0
0
215
1677
1.40
4.00
3.9
3.7
8.21
9.13
mg/mmol
0.11
140
1073
201
1550
1.41
3.99
4.4
3.7
0.00
0.01
estimate
1.08
81
550
193
1479
1.42
3.97
4.4
4.3
—
—
—
0
0
222
1748
1.39
3.89
3.7
3.1
7.00
7.96
mmol/l
2.84
193
1484
254
2046
1.37
3.87
4.5
3.6
128.51
62.51
e6/l
0.36
193
1431
284
2331
1.36
3.83
3.4
3.2
5.97
5.81
ph
0.30
17
188
14
38
3.74
3.81
2.9
3.1
—
—
—
0
0
217
1708
1.39
3.80
3.6
2.8
—
—
—
0
0
325
2731
1.34
3.73
7.3
6.8
1.22
1.21
mmol/l
0.90
281
2331
166
1253
1.42
3.69
1.9
1.9
—
—
—
0
0
119
846
1.49
3.62
2.4
2.2
29.63
29.60
s
0.02
119
821
603
5595
1.46
3.56
4.4
4.3
5.87
5.90
mmol/l
0.23
562
5135
201
1580
1.38
3.51
3.2
3.2
44.38
291.36
mg/l
1.94
137
1027
181
1405
1.38
3.40
2.4
2.1
2.76
2.99
mg/l
0.72
160
1209
267
2202
1.34
3.40
2.2
1.9
94.54
94.66
pmol/l
0.02
167
1155
130
953
1.44
3.38
1.6
1.7
1132.70
1188.71
nmol/l
0.37
100
730
15
53
2.87
3.37
2.8
3.0
—
—
—
0
0
22
95
2.36
3.36
1.2
1.1
—
12.35
—
0
8
64
402
1.65
3.35
2.7
2.7
184.53
162.98
ng/l
0.16
56
366
192
1511
1.37
3.31
1.7
1.7
1.43
1.36
mmol/l
0.51
171
1275
216
1745
1.34
3.12
3.9
3.1
58.83
101.11
e6/l
0.47
181
1342
19
80
2.41
3.08
1.9
2.7
—
—
—
0
0
104
746
1.46
3.03
2.5
2.2
22.88
23.12
%
0.06
89
646
98
695
1.47
3.03
1.4
1.7
—
—
—
0
0
165
1288
1.36
2.97
3.8
3.5
—
—
—
0
0
610
5719
1.41
2.97
4.5
4.2
4.61
4.64
mmol/l
0.27
570
5345
77
524
1.53
2.90
3.6
4.3
1.36
2.02
mmol/l
0.73
65
427
62
403
1.59
2.86
2.7
2.4
34.25
21.73
au/ml
—
6
31
51
316
1.66
2.84
2.6
2.6
0.12
0.20
e6/l
0.51
51
305
606
5688
1.39
2.81
4.3
4.1
1.44
1.46
mmol/l
0.28
555
5284
10
28
3.61
2.79
2.2
2.6
651.90
906.54
u/ml
—
10
28
99
717
1.44
2.75
1.4
1.6
—
—
—
0
0
66
440
1.55
2.74
1.3
1.5
—
—
—
0
0
88
624
1.47
2.73
1.3
1.3
—
—
—
0
0
107
788
1.42
2.72
2.0
2.1
—
—
—
0
0
686
6606
1.68
2.71
26.2
19.4
6.94
6.71
e9/l
2.05
675
6428
134
1026
1.38
2.71
1.5
1.6
—
—
—
0
0
6
10
6.04
2.70
1.0
1.0
0.08
1.79
u/ml
—
6
10
99
722
1.43
2.65
4.5
5.7
1.00
1.04
mmol/l
0.87
89
672
685
6598
1.66
2.65
26.2
19.4
255.77
250.54
e9/l
1.21
674
6441
18
80
2.28
2.62
1.7
1.5
—
—
—
0
0
685
6601
1.65
2.61
26.0
19.3
30.35
30.25
pg
0.72
679
6516
685
6601
1.65
2.61
26.1
19.3
91.05
90.68
fl
1.28
679
6517
615
5805
1.39
2.59
4.9
4.6
2.73
2.76
mmol/l
0.33
573
5389
685
6602
1.65
2.59
26.1
19.4
4.50
4.52
e12/l
0.47
675
6430
188
1526
1.31
2.57
3.8
3.0
—
—
—
0
0
30
164
1.86
2.57
2.2
2.1
12.61
11.37
mg/l
0.29
24
155
230
1920
1.29
2.55
3.2
3.3
29.72
32.64
u/l
1.18
220
1842
192
1566
1.31
2.53
3.8
3.0
0.27
0.49
e6/l
1.12
158
1185
685
6606
1.64
2.53
26.3
19.5
135.87
135.86
g/l
0.01
679
6516
185
1502
1.31
2.52
2.9
3.0
1297.81
1298.72
ng/l
0.00
156
1284
289
2485
1.27
2.52
6.7
6.1
1.22
1.21
mmol/l
0.51
268
2282
684
6600
1.61
2.44
26.6
19.4
40.24
40.32
%
0.13
637
6210
19
90
2.14
2.40
1.3
1.2
—
—
—
0
0
15
64
2.37
2.40
2.1
1.2
—
—
—
0
0
5
8
6.28
2.37
1.6
2.1
—
—
—
0
0
36
214
1.72
2.37
1.3
1.3
311.56
252.29
miu/ml
0.30
16
99
303
2636
1.26
2.36
3.2
2.7
107.62
117.05
ug/l
0.35
295
2456
75
533
1.45
2.32
2.9
2.0
297.03
377.29
nmol/l
3.04
69
498
157
1265
1.31
2.25
4.2
3.6
1.01
1.02
kg/l
1.68
28
169
18
86
2.12
2.24
1.4
1.4
60.33
62.39
mmol/l
0.07
12
76
195
1621
1.28
2.20
4.0
3.9
7.40
7.40
ph
0.21
38
304
24
129
1.89
2.19
1.7
1.6
6723.84
9199.98
e6/l
0.29
19
94
20
101
2.01
2.17
3.6
3.8
57.15
58.16
%
0.11
20
101
6
14
4.31
2.15
1.2
1.1
—
—
—
0
0
26
145
1.82
2.13
3.3
4.2
—
—
—
0
0
9
31
2.93
2.07
1.0
1.1
111.32
191.44
iu/ml
—
9
31
19
97
1.98
2.02
3.7
3.4
4.25
4.42
e9/l
0.09
19
97
57
397
1.47
1.98
2.9
2.5
4.34
6.19
e9/l
0.66
47
336
21
112
1.90
1.98
1.2
1.4
94.50
107.83
u/ml
—
6
23
7
21
3.36
1.97
1.0
1.1
1159.14
1682.86
miu/ml
—
7
21
18
91
2.00
1.96
1.6
1.2
—
—
—
0
0
557
5244
1.27
1.95
5.9
5.4
39.49
39.49
mmol/mol
0.00
533
4909
172
1428
1.27
1.95
4.4
3.9
88.36
90.79
%
0.54
166
1396
40
261
1.56
1.88
2.9
2.3
—
—
—
0
0
643
6176
1.36
1.88
16.2
12.4
—
—
—
0
0
160
1333
1.26
1.75
1.7
1.5
21.37
20.36
nmol/l
0.40
142
1134
68
503
1.39
1.73
4.6
3.4
—
—
—
0
0
50
351
1.46
1.70
1.4
1.2
—
—
—
0
0
53
377
1.44
1.68
3.7
4.0
81.25
77.82
ng/l
0.13
46
341
8
31
2.60
1.66
1.3
1.4
6.00
6.37
mmol/l
—
8
31
22
128
1.74
1.62
1.4
1.3
237.43
227.66
u/ml
0.07
14
68
426
3941
1.20
1.59
3.3
3.1
44.14
45.06
u/l
0.11
407
3714
6
20
3.02
1.58
3.7
2.3
—
—
—
0
0
29
184
1.60
1.56
1.2
1.1
—
—
—
0
0
576
5489
1.24
1.55
4.0
3.7
1.31
1.27
mmol/l
0.74
522
5077
21
123
1.73
1.52
1.2
1.5
—
—
—
0
0
6
21
2.87
1.51
2.5
2.2
—
—
—
0
0
25
156
1.62
1.45
1.2
1.4
252.75
296.20
ug/g
0.63
12
91
6
22
2.74
1.43
1.2
1.7
1.26
0.88
nmol/l
—
6
16
68
521
1.34
1.42
2.4
2.3
0.21
0.22
g/l
0.37
61
489
14
74
1.91
1.39
2.8
2.7
—
—
—
0
0
10
47
2.14
1.34
1.0
1.1
—
—
—
0
0
110
912
1.24
1.27
3.5
2.9
3.91
2.16
e6/l
0.75
79
498
37
261
1.44
1.27
2.2
3.2
0.58
0.64
%
0.56
37
261
136
1154
1.22
1.27
1.8
1.7
470.68
16358449.95
pmol/l
1.04
116
972
44
321
1.39
1.26
1.4
1.2
—
—
—
0
0
19
115
1.67
1.26
1.1
1.5
—
—
—
0
0
57
435
1.34
1.25
2.3
2.5
6.97
7.30
ug/l
0.05
47
387
83
669
1.27
1.22
1.6
1.5
—
—
—
0
0
25
165
1.53
1.19
1.5
1.1
—
—
—
0
0
56
430
1.33
1.18
2.6
3.9
1.23
1.23
mmol/l
0.02
50
375
12
64
1.89
1.18
1.2
1.2
—
—
—
0
0
209
1858
1.18
1.17
4.9
4.8
1.80
2.46
ug/l
1.78
184
1667
13
72
1.82
1.15
1.9
2.8
3.94
4.02
mmol/l
0.38
13
72
13
72
1.82
1.15
1.9
2.8
105.92
105.25
mmol/l
0.23
13
72
5
20
2.51
1.15
2.2
2.2
—
—
—
0
0
37
267
1.41
1.15
3.1
3.3
25.00
25.00
mmol/l
0.00
37
257
7
30
2.35
1.12
1.1
1.8
—
—
—
0
0
46
346
1.35
1.12
2.9
3.7
137.46
128.86
g/l
2.02
46
339
10
51
1.97
1.11
1.0
1.8
—
—
—
0
0
10
51
1.97
1.11
1.0
1.7
—
—
—
0
0
46
347
1.35
1.10
3.6
2.3
—
—
—
0
0
23
153
1.52
1.07
1.2
1.2
—
—
—
0
0
13
74
1.77
1.07
1.0
1.2
—
—
—
0
0
15
90
1.68
1.04
3.1
1.3
—
—
—
0
0
532
5097
1.16
1.04
23.3
16.9
333.00
332.98
g/l
0.02
527
5061
5
22
2.28
1.03
1.0
1.5
—
—
—
0
0
7
34
2.07
1.03
1.0
1.1
—
—
—
0
0
9
48
1.89
1.00
1.0
1.1
—
—
—
0
0
23
156
1.49
0.99
2.3
1.8
2.04
6.25
iu/l
—
7
51
9
49
1.85
0.99
1.0
1.4
—
—
—
0
0
5
23
2.18
0.98
1.0
1.3
—
—
—
0
0
5
23
2.18
0.98
4.2
2.9
42220.00
34908.91
ug/l
—
5
23
15
92
1.64
0.97
3.1
2.0
—
—
—
0
0
85
708
1.23
0.97
1.6
1.7
—
—
—
0
0
16
100
1.61
0.97
3.3
2.1
14.37
16.09
%
—
10
48
16
100
1.61
0.97
5.4
3.1
—
—
—
0
0
35
259
1.37
0.97
3.9
3.2
—
—
—
0
0
33
243
1.38
0.94
1.1
1.1
—
—
—
0
0
18
117
1.55
0.94
2.7
1.5
—
—
—
0
0
17
109
1.57
0.94
1.1
1.2
—
—
—
0
0
126
1095
1.18
0.93
3.0
2.9
0.61
0.77
ug/l
2.05
74
706
12
70
1.73
0.93
2.0
2.8
—
—
—
0
0
86
725
1.21
0.89
1.5
1.3
—
—
—
0
0
14
87
1.62
0.88
3.5
3.0
0.62
0.89
nmol/l
—
9
66
58
469
1.26
0.88
12.8
8.5
—
—
—
0
0
66
542
1.24
0.87
2.5
2.6
29.77
121.44
u/l
0.52
53
457
8
43
1.87
0.87
1.0
1.3
—
—
—
0
0
6
30
2.01
0.87
1.0
1.1
—
—
—
0
0
8
44
1.83
0.86
1.0
1.2
26.50
44.19
mg/l
—
8
35
73
608
1.22
0.85
9.3
8.2
4.95
5.08
kpa
0.57
68
585
73
609
1.22
0.84
9.3
8.2
11.38
12.29
kpa
1.32
68
589
6
31
1.94
0.84
1.2
1.3
—
—
—
0
0
6
31
1.94
0.84
1.3
4.4
—
—
—
0
0
298
2774
1.13
0.84
3.0
2.6
—
—
—
0
0
12
73
1.65
0.82
1.2
1.4
—
—
—
0
0
59
485
1.24
0.79
1.3
1.2
—
—
—
0
0
6
33
1.82
0.79
1.0
1.5
—
—
—
0
0
35
271
1.31
0.76
2.8
2.2
16887.13
4141.18
u/l
0.55
14
115
176
1596
1.14
0.75
4.1
3.7
—
—
—
0
0
11
67
1.65
0.75
1.2
1.4
—
—
nmol/l
—
0
0
25
184
1.37
0.74
5.0
1.7
—
—
—
0
0
5
25
2.01
0.73
3.2
2.2
46.00
89.10
ug/l
—
5
25
36
282
1.29
0.72
17.2
11.1
—
—
—
0
0
7
40
1.76
0.71
1.3
1.0
—
—
—
0
0
45
364
1.25
0.71
3.4
3.5
7.39
7.41
ph
—
9
35
9
59
1.53
0.68
1.0
1.2
—
—
—
0
0
14
94
1.50
0.67
2.9
2.6
—
—
—
0
0
7
43
1.63
0.67
1.0
1.1
158.14
234.32
mg/l
—
7
37
5
28
1.79
0.66
1.0
4.5
63.80
91.11
nmol/l
—
5
28
5
28
1.79
0.66
1.0
1.4
1.55
1.52
g/l
—
5
28
71
609
1.18
0.65
10.5
8.2
1.03
1.16
mmol/l
0.10
57
491
14
95
1.48
0.64
1.5
1.7
—
—
—
0
0
5
29
1.73
0.64
4.0
2.2
13.78
16.70
ug/l
—
5
24
5
29
1.73
0.64
1.6
1.2
—
—
—
0
0
200
1847
1.11
0.63
3.3
2.3
—
—
—
0
0
20
147
1.37
0.62
1.1
1.5
561.00
475.89
mg/l
0.29
20
138
5
30
1.67
0.61
1.0
1.0
—
—
—
0
0
5
30
1.67
0.61
1.6
1.3
—
—
—
0
0
0
22
0.00
0.59
0.0
1.4
—
—
—
0
0
16
114
1.41
0.59
1.1
1.8
—
—
—
0
0
14
98
1.44
0.57
1.1
1.0
—
—
—
0
0
6
37
1.63
0.55
1.3
1.5
110.00
75.08
umol/l
—
6
37
9
63
1.43
0.52
2.0
1.7
87.86
90.43
%
—
9
63
9
132
0.68
0.52
1.4
1.3
—
—
—
0
0
51
435
1.19
0.52
3.9
3.3
—
—
—
0
0
13
92
1.42
0.50
1.5
1.6
—
—
—
0
0
17
127
1.35
0.50
3.8
2.0
—
—
—
0
0
10
67
1.50
0.50
2.2
1.3
—
—
—
0
0
29
236
1.24
0.47
2.3
1.6
—
—
—
0
0
149
1380
1.10
0.46
2.9
2.3
—
—
—
0
0
7
51
1.38
0.44
1.9
2.8
48.71
57.54
%
—
7
46
7
51
1.38
0.44
1.3
1.1
—
—
—
0
0
5
31
1.62
0.43
1.2
1.1
—
—
—
0
0
5
33
1.52
0.41
1.0
1.0
—
—
—
0
0
0
15
0.00
0.41
0.0
1.2
—
60.53
—
0
15
8
59
1.36
0.41
1.1
1.7
—
—
—
0
0
74
665
1.13
0.40
2.3
3.1
7.15
8.93
umol/l
0.42
59
583
28
232
1.22
0.40
1.7
1.3
—
—
—
0
0
5
34
1.47
0.40
1.0
1.5
0.84
1.01
g/l
—
5
34
64
571
1.13
0.39
2.4
4.3
109.80
31.62
ug/l
0.39
46
478
5
35
1.43
0.39
1.4
1.4
—
—
—
0
0
48
420
1.15
0.39
1.3
1.2
122.57
155.07
iu/ml
0.24
23
169
5
36
1.39
0.38
1.6
1.3
—
—
—
0
0
9
67
1.35
0.38
1.1
2.0
13.00
13.24
%
—
9
67
15
116
1.30
0.37
3.8
4.2
—
—
—
0
0
23
273
0.84
0.32
1.1
1.1
—
—
—
0
0
12
92
1.31
0.32
1.2
1.3
5.33
4.50
u/ml
—
6
38
65
592
1.11
0.30
1.5
1.4
—
—
—
0
0
8
109
0.73
0.29
1.0
1.2
—
—
—
0
0
8
63
1.27
0.28
1.3
1.1
—
—
—
0
0
8
65
1.23
0.27
1.1
1.7
13.34
15.88
ug/l
—
8
65
25
215
1.17
0.27
2.4
1.3
—
—
—
0
0
13
104
1.25
0.26
1.5
1.3
—
—
—
0
0
8
67
1.20
0.26
1.1
1.1
—
—
—
0
0
24
208
1.16
0.24
2.9
4.7
—
—
—
0
0
6
83
0.72
0.24
1.2
1.1
1.49
1.45
g/l
—
6
76
56
514
1.10
0.24
3.9
4.1
—
—
—
0
0
26
227
1.15
0.24
4.8
3.4
0.34
0.25
g/l
0.19
15
99
5
38
1.32
0.23
1.2
3.8
—
—
—
0
0
170
1768
0.95
0.22
1.4
1.5
—
—
—
0
0
43
392
1.10
0.21
1.2
1.4
—
—
—
0
0
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.3
—
—
—
0
0
0
10
0.00
0.21
0.0
1.2
—
1.81
—
0
10
0
12
0.00
0.21
0.0
8.7
—
—
—
0
0
38
345
1.11
0.20
4.7
5.8
—
—
—
0
0
10
123
0.81
0.20
2.6
4.2
12.20
23.46
mg/l
—
5
83
13
108
1.21
0.20
1.2
1.1
—
—
—
0
0
10
121
0.82
0.18
1.9
1.2
—
—
—
0
0
5
68
0.73
0.17
1.0
1.3
—
—
—
0
0
14
123
1.14
0.12
1.1
1.1
1.50
3.55
u/ml
—
9
68
60
629
0.95
0.12
1.3
1.3
—
—
—
0
0
12
135
0.89
0.10
1.0
1.1
—
—
—
0
0
5
45
1.11
0.10
1.0
1.3
—
—
—
0
0
5
46
1.09
0.09
1.0
1.0
323.00
293.51
mg/l
—
5
41
27
252
1.07
0.09
2.3
1.4
—
—
—
0
0
41
390
1.05
0.09
1.4
1.4
—
—
—
0
0
5
64
0.78
0.08
1.6
3.6
—
—
—
0
0
7
67
1.05
0.08
1.1
1.1
—
—
—
0
0
6
75
0.80
0.07
1.8
2.6
—
—
—
0
0
7
81
0.86
0.07
1.6
1.9
—
—
—
0
0
7
84
0.83
0.07
5.3
6.3
9.84
11.39
mg/l
—
7
76
29
277
1.05
0.05
3.0
3.8
—
—
—
0
0
26
272
0.95
0.04
2.4
1.4
—
—
—
0
0
16
170
0.94
0.04
1.6
1.7
52.56
40.59
nmol/l
0.50
16
160
16
169
0.95
0.03
1.4
1.5
—
—
—
0
0
22
228
0.96
0.02
3.5
2.8
—
—
—
0
0
216
2148
1.01
0.02
2.5
2.7
—
—
—
0
0
13
123
1.06
0.01
2.2
4.7
—
—
—
0
0
13
137
0.95
0.01
2.4
3.6
31.62
34.82
umol/l
0.19
13
124
18
187
0.96
0.01
9.8
10.4
—
—
—
0
0
16
164
0.98
0.00
1.4
1.4
—
—
—
0
0
16
164
0.98
0.00
1.5
1.4
—
—
—
0
0
27
274
0.98
0.00
2.7
1.4
—
—
—
0
0
27
274
0.98
0.00
2.3
1.4
—
—
—
0
0
10
102
0.98
0.00
1.0
1.1
—
—
—
0
0
33
327
1.01
0.00
1.7
1.7
—
—
—
0
0
27
272
0.99
0.00
2.3
1.4
—
—
—
0
0
10
101
0.99
0.00
1.0
1.1
—
—
—
0
0
0
8
0.00
0.00
0.0
1.4
—
—
—
0
0
0
8
0.00
0.00
0.0
1.1
—
41.75
—
0
8
0
8
0.00
0.00
0.0
1.3
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
15.00
—
0
6
0
9
0.00
-0.00
0.0
9.3
—
—
—
0
0
0
6
0.00
-0.00
0.0
3.5
—
—
—
0
0
0
5
0.00
-0.00
0.0
7.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
72.66
—
0
5
12
120
1.00
-0.00
1.4
1.7
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
2.4
—
190.40
—
0
5
0
6
0.00
-0.00
0.0
1.3
—
95.17
—
0
6
6
65
0.92
-0.00
1.5
2.4
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
5
58
0.86
-0.00
2.4
2.6
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
15.57
—
0
7
5
59
0.85
-0.00
5.6
6.9
7.28
6.92
mmol/l
—
5
44

Mortality – FinRegistry

Association

Association between endpoint L12_PARAPSORI and mortality.

Females

Parameter HR [95% CI] p-value
L12_PARAPSORI 1.115 [0.94, 1.32] 0.2
Birth year 0.997 [0.99, 1.01] 0.585

During the follow-up period (1.1.1998 — 31.12.2019), 221 out of 2204 females with L12_PARAPSORI died.

Males

Parameter HR [95% CI] p-value
L12_PARAPSORI 0.996 [0.87, 1.14] 0.949
Birth year 0.988 [0.98, 1.0] 0.026

During the follow-up period (1.1.1998 — 31.12.2019), 354 out of 2069 males with L12_PARAPSORI died.

Mortality risk

Mortality risk for people of age

years, who have L12_PARAPSORI.

N-year risk Females Males
1 0.097% 0.203%
5 0.617% 1.12%
10 1.461% 2.943%
15 2.779% 5.843%
20 5.352% 10.016%

Relationships between endpoints

Index endpoint: L12_PARAPSORI – Parapsoriasis

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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