parapsoriasis: one of a group of skin disorders that are characterized primarily by their resemblance to psoriasis (red, scaly lesions), rather than by their underlying etiology. Neoplasms can develop from parapsoriasis. For example, it can develop into cutaneous T-cell lymphoma.
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
519972 |
1. Apply sex-specific ruleNone |
519972 |
2. Check conditionsNone |
519972 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
144 |
4. Check minimum number of eventsNone |
144 |
5. Include endpointsNone |
144 |
6. Filter based on genotype QC (FinnGen only) |
139 |
Control definitions (FinnGen only)
- Control exclude
- L12_PAPULOSQUAMOUS
Extra metadata
- Level in the ICD hierarchy
- 4
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- L41
- Name in latin
- Pityriasis lichenoides chronica
Similar endpoints
↥List of similar endpoints to
Pityriasis lichenoides chronica
based on the number of shared cases.
Similar with more cases:
- Parapsoriasis
- Papulosquamous disorders
- Diseases of the skin and subcutaneous tissue
- Any operation in hilmo
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 1094 | 573 | 516 |
| Only index persons | 1012 | 541 | 471 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.02 | 0.02 | 0.01 |
| Only index persons | 0.02 | 0.02 | 0.02 |
| Median age at first event (years) | |||
| Whole population | 47.37 | 51.09 | 43.22 |
| Only index persons | 46.68 | 50.15 | 42.71 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 139 | 72 | 67 |
| Unadjusted period prevalence (%) | 0.03 | 0.03 | 0.03 |
| Median age at first event (years) | 55.72 | 53.42 | 58.20 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
No data
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 144
- Matched controls
- 1440
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
L41.1
ICD-10 Finland
Pityriasis lichenoides chronica
+∞
194.4
139
*
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
19.1
69.0
70
68
L30.9
ICD-10 Finland
Dermatitis, unspecified
8.8
38.4
74
155
D07AC01
ATC
betamethasone; topical
7.4
31.9
93
286
E0000UV, ,
ATC
7.7
30.0
106
384
D07AD01
ATC
clobetasol; topical
6.7
24.4
50
106
D07AB02
ATC
hydrocortisone butyrate; topical
5.4
23.1
80
269
D07AB08
ATC
desonide; topical
6.4
21.6
44
92
WXQ27
NOMESCO Finland
UVB narrow spectrum light therapy
243.8
21.2
21
*
D07AC13
ATC
mometasone; topical
5.0
20.6
71
234
D02AE01
ATC
carbamide; topical
8.3
16.7
24
34
L40.0
ICD-10 Finland
Psoriasis vulgaris
63.7
15.1
17
*
E000002, ,
ATC
5.2
14.1
34
81
D07BA04
ATC
hydrocortisone and antiseptics; topical
5.2
13.8
33
78
E000001, ,
ATC
4.0
13.5
52
178
L41.4
ICD-10 Finland
Large plaque parapsoriasis
+∞
12.7
12
*
D07XC01
ATC
betamethasone; topical
4.8
11.3
29
72
XQ848
NOMESCO Finland
Dermatological photography
14.6
10.5
17
13
L41.0
ICD-10 Finland
Pityriasis lichenoides et varioliformis acuta
+∞
9.5
9
*
D07AA02
ATC
hydrocortisone; topical
3.7
9.2
35
116
L43.8
ICD-10 Finland
Other lichen planus
95.4
8.5
9
*
D07BB04
ATC
hydrocortisone butyrate and antiseptics; topical
3.3
7.3
32
115
E000007, ,
ATC
4.8
7.2
17
39
H02AB06
ATC
prednisolone; systemic
2.6
7.1
81
482
D05AX52
ATC
calcipotriol, combinations; topical
10.1
6.9
13
14
D02AX
ATC
Other emollients and protectives
8.5
6.8
14
18
D05AX02
ATC
calcipotriol; topical
23.8
6.8
9
*
D09AB01
ATC
zinc bandage without supplements; topical
13.1
6.7
11
9
R21
ICD-10 Finland
Rash and other nonspecific skin eruption
5.9
6.4
17
32
L43.9
ICD-10 Finland
Lichen planus, unspecified
28.0
6.3
8
*
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
30
134
2.56
4.55
3.5
4.3
232.73
238.62
u/l
0.15
30
126
36
199
2.08
3.29
1.3
1.3
31.62
27.18
iu/ml
0.10
11
72
52
328
1.92
3.28
3.5
3.6
4.14
7.11
mg/mmol
0.61
31
202
13
46
3.01
3.00
1.5
1.9
—
—
—
0
0
34
196
1.96
2.75
4.4
3.4
177.33
152.13
ng/l
0.06
24
150
6
10
6.20
2.72
1.3
1.1
—
—
—
0
0
11
35
3.32
2.71
1.4
1.9
0.26
0.24
g/l
0.15
11
35
34
197
1.95
2.71
1.3
1.3
1.10
12.87
u/ml
1.46
11
73
11
36
3.22
2.63
1.4
1.9
1.24
1.17
g/l
0.44
11
36
67
485
1.71
2.56
4.4
5.0
34.77
35.77
g/l
0.75
59
463
105
863
1.80
2.51
5.5
3.9
11.10
11.65
mm/h
0.17
98
789
45
299
1.73
2.30
1.6
1.6
1.26
1.33
mmol/l
0.27
39
246
48
329
1.69
2.18
2.6
3.0
336.98
5767.48
umol/l
1.56
43
284
103
862
1.68
2.09
4.6
4.0
15.12
14.78
pmol/l
0.64
95
776
40
268
1.68
1.95
1.4
1.3
1.88
1.75
u/ml
0.04
17
71
7
22
3.29
1.90
1.6
1.3
—
—
—
0
0
5
12
4.27
1.84
1.0
1.0
—
—
—
0
0
38
262
1.61
1.65
1.9
2.1
1.12
1.51
mg/l
0.37
30
205
6
20
3.08
1.60
1.3
2.1
—
—
—
0
0
9
39
2.39
1.46
1.3
1.2
—
1.71
—
0
7
10
46
2.26
1.43
2.5
2.8
—
—
—
0
0
5
19
2.69
1.22
6.4
2.4
54.80
53.53
%
—
5
19
5
19
2.69
1.22
1.0
1.1
—
—
—
0
0
8
38
2.17
1.20
1.8
1.5
—
—
—
0
0
24
161
1.59
1.16
2.9
6.2
1.07
1.03
mmol/l
0.40
18
149
50
393
1.42
1.14
3.8
3.5
2.32
2.35
mmol/l
0.92
44
354
26
179
1.55
1.13
2.1
2.4
28.73
29.58
s
0.49
26
174
58
470
1.39
1.11
2.4
2.4
88.58
75.46
nmol/l
2.19
53
412
116
1060
1.49
1.07
5.7
4.7
1.92
1.94
mu/l
0.08
107
961
54
439
1.37
0.99
5.1
4.1
—
—
—
0
0
7
36
1.99
0.98
1.0
1.1
—
—
—
0
0
11
62
1.84
0.97
4.3
3.7
4.60
4.53
pmol/l
0.08
11
57
6
27
2.27
0.94
1.2
1.4
—
—
—
0
0
56
466
1.33
0.87
3.6
4.1
19.31
49.49
ng/l
2.38
31
338
38
298
1.37
0.86
5.9
4.2
0.00
0.00
estimate
-0.00
13
111
63
535
1.32
0.85
14.3
15.4
1.10
1.28
inr
2.05
22
152
5
100
0.48
0.80
1.0
1.7
—
—
—
0
0
125
1177
1.47
0.79
17.0
14.8
19.72
22.93
mg/l
0.56
98
918
37
293
1.35
0.79
4.7
4.6
18.77
21.44
%
0.47
13
152
9
54
1.71
0.76
1.4
1.6
—
—
—
0
0
103
1104
0.76
0.70
4.0
4.0
1.36
1.26
mmol/l
0.44
90
1007
0
20
0.00
0.61
0.0
1.1
—
—
—
0
0
0
21
0.00
0.60
0.0
3.2
—
178.89
—
0
21
6
38
1.60
0.55
1.5
1.5
—
—
—
0
0
17
127
1.38
0.52
1.4
1.7
—
—
—
0
0
10
67
1.53
0.51
1.4
1.7
—
—
—
0
0
23
182
1.31
0.50
1.4
1.8
—
—
—
0
0
23
183
1.31
0.49
5.5
3.9
0.78
0.83
mmol/l
1.03
18
171
17
129
1.36
0.48
1.4
1.7
—
—
—
0
0
15
112
1.38
0.47
2.0
2.2
316.87
374.27
nmol/l
0.49
15
102
63
566
1.20
0.47
4.8
3.8
0.00
0.00
estimate
-0.00
14
116
63
566
1.20
0.47
6.6
7.7
1.21
1.21
mmol/l
0.13
56
477
26
212
1.28
0.46
1.8
1.6
—
—
—
0
0
63
568
1.19
0.44
5.9
5.3
0.00
0.00
estimate
-0.00
14
107
50
442
1.20
0.43
2.1
2.0
93.76
94.63
pmol/l
0.04
29
221
5
31
1.63
0.43
1.0
1.2
—
—
—
0
0
129
1247
1.33
0.42
13.3
10.1
26.65
25.89
u/l
0.23
124
1208
12
88
1.40
0.41
1.2
1.4
—
—
—
0
0
0
15
0.00
0.41
0.0
1.8
—
—
—
0
0
0
17
0.00
0.41
0.0
1.7
—
—
—
0
0
0
17
0.00
0.41
0.0
1.8
—
—
—
0
0
63
573
1.18
0.39
4.8
3.9
0.21
0.00
estimate
0.47
14
101
0
19
0.00
0.39
0.0
1.6
—
—
—
0
0
26
217
1.24
0.39
1.3
1.7
1353.28
1210.35
nmol/l
0.39
16
164
9
70
1.30
0.37
1.1
1.0
—
—
—
0
0
6
41
1.48
0.36
1.7
1.8
—
—
—
0
0
60
547
1.17
0.36
3.2
2.8
—
—
—
0
0
6
43
1.41
0.35
1.5
1.5
—
—
—
0
0
10
74
1.38
0.33
5.7
7.3
25.59
24.46
mmol/l
—
10
74
49
446
1.15
0.29
4.1
3.2
—
—
—
0
0
5
37
1.36
0.24
5.4
4.2
97.70
232.71
mg/l
—
5
31
5
37
1.36
0.24
5.4
4.2
31.68
23.35
mg/l
—
5
31
42
384
1.13
0.23
4.3
5.0
1.47
2.13
ug/l
1.40
37
343
79
752
1.11
0.22
2.8
3.0
—
—
—
0
0
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
195.39
—
0
10
0
10
0.00
0.21
0.0
1.2
—
—
—
0
0
0
12
0.00
0.21
0.0
4.7
—
—
—
0
0
112
1088
1.13
0.21
16.4
13.8
83.37
81.78
ml/min/173m2
0.33
96
879
0
14
0.00
0.20
0.0
4.5
—
119.12
—
0
14
0
14
0.00
0.20
0.0
1.2
—
—
—
0
0
133
1308
1.22
0.19
26.9
21.2
251.01
245.75
e9/l
0.43
133
1276
7
60
1.18
0.18
1.4
1.5
—
—
—
0
0
14
120
1.18
0.17
4.1
3.8
—
—
—
0
0
133
1310
1.20
0.16
26.9
21.2
4.48
4.51
e12/l
0.35
133
1274
133
1310
1.20
0.16
26.7
21.4
40.32
40.19
%
0.10
123
1242
133
1310
1.20
0.16
27.1
21.4
134.83
135.71
g/l
0.29
133
1292
119
1166
1.12
0.15
5.1
4.9
2.64
2.70
mmol/l
0.33
108
1066
10
115
0.86
0.11
5.7
5.4
5.29
5.80
kpa
—
10
110
36
340
1.08
0.10
2.0
3.3
1882.46
1675.87
ng/l
0.09
29
291
16
176
0.90
0.10
1.8
1.4
—
—
—
0
0
33
348
0.93
0.09
4.3
3.1
0.54
0.35
e6/l
0.20
28
269
16
149
1.08
0.05
4.9
7.6
103.13
103.68
mmol/l
0.16
16
149
11
120
0.91
0.05
2.7
1.8
—
—
—
0
0
116
1150
1.04
0.03
4.3
4.4
4.53
4.58
mmol/l
0.15
105
1061
29
284
1.03
0.00
2.1
2.5
—
—
—
0
0
12
119
1.01
0.00
2.3
4.5
704.10
62.42
ug/l
—
7
103
12
117
1.03
0.00
3.2
2.7
35.25
29.00
u/l
0.38
12
92
15
147
1.02
0.00
5.7
7.2
—
—
—
0
0
21
213
0.98
0.00
2.5
2.9
0.42
0.79
ug/l
2.64
12
140
113
1127
1.01
0.00
5.0
4.6
6.06
5.99
mmol/l
0.27
101
1034
106
1055
1.02
0.00
6.9
5.9
41.21
40.20
mmol/mol
0.51
101
987
13
135
0.96
0.00
2.9
2.0
1.37
1.55
%
0.65
13
119
13
132
0.98
0.00
2.8
2.0
—
—
—
0
0
114
1138
1.01
0.00
4.3
4.4
1.50
1.45
mmol/l
0.51
100
1042
17
175
0.97
0.00
1.8
2.1
2.43
2.40
g/l
0.10
17
155
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
2.0
—
—
—
0
0
0
6
0.00
0.00
0.0
4.2
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
2.3
—
—
—
0
0
0
6
0.00
0.00
0.0
4.2
—
—
—
0
0
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
7
75
0.93
-0.00
1.1
1.4
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
20.40
—
0
5
0
5
0.00
-0.00
0.0
1.8
—
—
—
0
0
0
8
0.00
-0.00
0.0
6.6
—
237.63
—
0
8
0
7
0.00
-0.00
0.0
1.0
—
92.57
—
0
7
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
0
9
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
2.6
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
-0.00
0.0
2.6
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint L12_PARAPSO_PITYLICHCHRON and mortality.
Females
No dataMales
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| L12_PARAPSO_PITYLICHCHRON | 1.103 [0.81, 1.5] | 0.535 |
| Birth year | 0.986 [0.98, 1.0] | 0.004 |
During the follow-up period (1.1.1998 — 31.12.2019), 59 out of 434 males with L12_PARAPSO_PITYLICHCHRON died.
Mortality risk
Mortality risk for people of age
years, who have L12_PARAPSO_PITYLICHCHRON.| N-year risk | Females | Males |
|---|---|---|
| 1 | No data | 0.262% |
| 5 | No data | 1.381% |
| 10 | No data | 3.296% |
| 15 | No data | 5.941% |
| 20 | No data | 10.029% |
Relationships between endpoints
↥Index endpoint: L12_PARAPSO_PITYLICHCHRON – Pityriasis lichenoides chronica
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
Loading data