Habit and impulse disorders

F5_HABIT

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 F63
  • Hospital discharge: ICD-9 312
  • Cause of death: ICD-10 F63
  • Cause of death: ICD-9 312

2 out of 7 registries used, show all original rules.

637

4. Check minimum number of events

None

637

5. Include endpoints

None

637

6. Filter based on genotype QC (FinnGen only)

637

Control definitions (FinnGen only)

Control exclude
F5_PERSOBEH

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
F63-F69
Name in latin
Perturbationes habituum et impulsuum

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 6737 2297 4406
Only index persons 6147 2125 4022
Unadjusted period prevalence (%)
Whole population 0.10 0.07 0.12
Only index persons 0.13 0.08 0.15
Median age at first event (years)
Whole population 25.91 28.58 24.44
Only index persons 25.47 27.90 24.18

-FinnGen-

Key figures

All Female Male
Number of individuals 637 264 373
Unadjusted period prevalence (%) 0.13 0.09 0.16
Median age at first event (years) 33.85 34.03 33.72

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
589
Matched controls
5889
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
F63.0
ICD-10 Finland
Pathological gambling
893.6
318.6
285
6
N05AH04
ATC
quetiapine; oral
10.0
124.8
304
565
F63.8
ICD-10 Finland
Other habit and impulse disorders
1258.0
110.2
104
*
112
Kela drug reimbursment
Severe psychotic and other severe mental disorders
13.3
106.8
203
223
F60.30
ICD-10 Finland
Emotionally unstable personality disorder, impulsive
+∞
98.8
92
*
F32.9
ICD-10 Finland
Depressive episode, unspecified
9.0
97.4
240
419
F63.9
ICD-10 Finland
Habit and impulse disorder, unspecified
+∞
92.1
86
*
N05AH03
ATC
olanzapine; systemic
11.9
84.9
168
191
N06AB04
ATC
citalopram; systemic
7.0
84.5
255
581
N05AX08
ATC
risperidone; systemic
12.5
78.6
150
156
N03AG01
ATC
valproic acid; systemic, rectal
12.2
76.7
148
157
T36
ICD-10 Finland
Poisoning by systemic antibiotics
15.6
76.6
131
106
N05AA02
ATC
levomepromazine; systemic
19.3
74.2
116
74
F61.0
ICD-10 Finland
Mixed personality disorders
726.7
67.4
65
*
F60.31
ICD-10 Finland
Emotionally unstable personality disorder, borderline condition
+∞
67.0
63
*
F10.1
ICD-10 Finland
Mental and behavioural disorders due to use of alcohol, Harmful use
9.7
66.2
145
192
F41.9
ICD-10 Finland
Anxiety disorder, unspecified
7.6
66.1
173
305
N05BA04
ATC
oxazepam; oral
5.5
65.9
244
675
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
7.4
65.4
174
314
N05AX12
ATC
aripiprazole; systemic
11.9
65.0
126
132
N06AB03
ATC
fluoxetine; oral
7.5
63.6
167
294
N06AX16
ATC
venlafaxine; oral
6.4
62.8
191
412
X69
ICD-10 Finland
Intentional self-poisoning by and exposure to other and unspecified chemicals and noxious substances
16.2
61.3
102
75
N05AB03
ATC
perphenazine; systemic, rectal
22.7
58.7
86
44
N05AF03
ATC
chlorprothixene; systemic
19.5
55.8
86
51
N06AB06
ATC
sertraline; oral
6.6
55.5
160
315
P29
ICPC
Psychological sympt/compl other
8.4
52.3
124
182
N06AX11
ATC
mirtazapine; oral
4.2
52.3
271
1002
F32.2
ICD-10 Finland
Severe depressive episode without psychotic symptoms
8.5
51.3
120
172
F33.2
ICD-10 Finland
Recurrent depressive disorder, current episode severe without psychotic symptoms
11.1
49.5
98
104
F33.9
ICD-10 Finland
Recurrent depressive disorder, unspecified
11.2
49.2
97
102
N05BA01
ATC
diazepam; systemic, rectal
6.1
49.0
148
305
F32.10
ICD-10 Finland
Moderate depressive episode without somatic syndrome
6.6
48.6
138
262
F33.10
ICD-10 Finland
Recurrent depression, moderate episode without somatic syndrome
9.1
48.5
108
142
F29
ICD-10 Finland
Unspecified nonorganic psychosis
9.0
47.8
107
142
3120A
ICD-9 Finland
Disturbance of conduct not elsewhere classified, Undersocialised conduct disorder, aggressive type
+∞
47.5
45
*
F60.3
ICD-10 Finland
Emotionally unstable personality disorder
254.8
46.7
47
*
N07BB01
ATC
disulfiram; oral
9.2
46.0
101
129
F60.9
ICD-10 Finland
Personality disorder, unspecified
102.0
43.5
47
5
N06AB10
ATC
escitalopram; oral
4.0
43.2
219
765
F10.29
ICD-10 Finland
Addiction caused by alcohol UNS
16.8
42.7
69
46
N05CD07
ATC
temazepam; oral
7.5
42.0
106
168
N06AX12
ATC
bupropion; oral
6.6
41.0
113
203
N04AA02
ATC
biperiden; systemic
22.5
40.5
59
29
F20.9
ICD-10 Finland
Schizophrenia, unspecified
16.4
40.4
66
45
N03AX09
ATC
lamotrigine; oral
9.0
40.3
89
114
IEY05
NOMESCO Finland
Dedicated profession-specific psychiatric intervention, individual
11.9
39.9
75
71
ICZ03
NOMESCO Finland
Participation in compiling a psychiatric treatment plan
11.0
38.8
76
78
F10.20
ICD-10 Finland
Alcohol dependence currently independent
16.8
38.4
62
41
N05AD01
ATC
haloperidol; systemic
16.9
37.9
61
40
F31.9
ICD-10 Finland
Bipolar affective disorder, unspecified
12.7
37.3
68
60
N05CF01
ATC
zopiclone; oral
3.5
36.4
214
822
IGY99
NOMESCO Finland
Other psychiatric treatment contact
13.8
34.4
60
48
N05BA06
ATC
lorazepam; systemic, sublingual
10.5
33.6
67
71
N05AH02
ATC
clozapine; systemic
12.5
31.8
58
51
P99
ICPC
Psychological disorders other
9.6
31.6
66
76
ICB01
NOMESCO Finland
Psychiatric treatment plan, standard
10.2
30.7
62
67
F31.6
ICD-10 Finland
Bipolar affective disorder, current episode mixed
19.8
30.6
46
25
SPAT1240
SPAT
Therapeutic discussion
3.9
30.5
141
435
3018D
ICD-9 Finland
Personality disorders, Other personality disorders[EPÄVAKAA PERSOONALLISUUS]
+∞
30.5
29
*
F31.8
ICD-10 Finland
Other bipolar affective disorders
13.1
30.4
54
45
P15
ICPC
Chronic alcohol abuse
9.4
30.3
64
75
P01
ICPC
Feeling anxious/nervous/tense
3.9
30.1
139
428
N03AE01
ATC
clonazepam; systemic
7.9
30.1
71
100
F20.00
ICD-10 Finland
Paranoid schizophrenia continuous
12.5
29.8
54
47
IGY02
NOMESCO Finland
Psychiatric monitoring contact
12.0
29.7
55
50
F99
ICD-10 Finland
Mental disorder, not otherwise specified
13.2
29.3
52
43
F31.4
ICD-10 Finland
Bipolar affective disorder, current episode severe depression without psychotic symptoms
19.7
29.2
44
24
N05AN01
ATC
lithium; oral
11.6
29.2
55
52
F31.30
ICD-10 Finland
Bipolar disorder Depressive episode without somatic syndrome
14.3
28.8
49
37
F63.3
ICD-10 Finland
Trichotillomania
+∞
28.4
27
*
N05AA01
ATC
chlorpromazine; systemic, rectal
21.9
28.2
41
20
F10.21
ICD-10 Finland
Alcohol dependence currently abstinent, but staying in restrictive environment
28.1
27.4
37
14
X44
ICD-10 Finland
Accidental poisoning by and exposure to other and unspecified drugs, medicaments and biological substances
18.0
27.0
42
25
F20.30
ICD-10 Finland
Undifferentiated schizophrenia continuous
13.0
27.0
48
40
F10.26
ICD-10 Finland
Alcohol dependence periodic alcoholism
14.7
26.7
45
33
ICB03
NOMESCO Finland
Psychiatric treatment plan, monitoring
19.4
26.5
40
22
N05BA02
ATC
chlordiazepoxide; systemic
17.5
26.2
41
25
F41.1
ICD-10 Finland
Generalized anxiety disorder
6.1
26.1
74
135
F60.8
ICD-10 Finland
Other specific personality disorders
141.2
25.8
27
*
F41.2
ICD-10 Finland
Mixed anxiety and depressive disorder
4.2
25.8
107
296
F31.0
ICD-10 Finland
Bipolar affective disorder, current episode hypomanic
20.2
25.5
38
20
EBA00
NOMESCO Finland
Extraction of tooth
2.6
25.5
258
1349
F10.25
ICD-10 Finland
Alcohol dependence continuous use
15.0
25.2
42
30
F60.2
ICD-10 Finland
Dissocial personality disorder
+∞
25.2
24
*
3039X
ICD-9 Finland
Alcohol dependence syndrome, Other and unspecified alcohol dependence
36.2
24.5
31
9
EB1AA
NOMESCO Finland
Tooth X-ray examination
2.4
23.4
376
2476
K02.1
ICD-10 Finland
Caries of dentine
2.5
23.3
415
2881
F61
ICD-10 Finland
Mixed and other personality disorders
+∞
23.1
22
*
F32.00
ICD-10 Finland
Mild depressive episode without somatic syndrome
6.5
22.9
61
102
WX110
NOMESCO Finland
Local anesthesy
2.6
22.8
457
3357
N06AX03
ATC
mianserin; oral
8.2
22.6
51
67
F21
ICD-10 Finland
Schizotypal disorder
36.6
22.2
28
8
P72
ICPC
Schizophrenia
10.7
22.2
43
43
F25.9
ICD-10 Finland
Schizoaffective disorder, unspecified
13.0
22.1
39
32
F60.0
ICD-10 Finland
Paranoid personality disorder
+∞
22.0
21
*
IGY01
NOMESCO Finland
Accelerated psychiatric treatment contact
9.3
22.0
46
53
F51.0
ICD-10 Finland
Nonorganic insomnia
3.3
22.0
126
452
IBZ01
NOMESCO Finland
Profession-specific psychiatric evaluation
10.5
21.9
43
44
F34.1
ICD-10 Finland
Dysthymia
8.7
21.6
47
58
F40.1
ICD-10 Finland
Social phobias
7.2
21.1
52
78
F33.00
ICD-10 Finland
Recurrent depression, mild episode without somatic syndrome
11.5
21.0
39
36
F41.09
ICD-10 Finland
UNS Panic Syndrome
7.8
20.7
48
66
F90.0
ICD-10 Finland
Disturbance of activity and attention
6.0
20.4
58
106
K04.5
ICD-10 Finland
Chronic apical periodontitis
2.6
20.2
182
866
F10.24
ICD-10 Finland
Alcohol depence active use
12.3
20.0
36
31
2968A
ICD-9 Finland
Affective psychoses, Manic-depressive psychosis, other and unspecified
25.6
19.7
27
11
Z03.2
ICD-10 Finland
Observation for suspected mental and behavioural disorders
11.2
19.7
37
35
SPAT1254
SPAT
Administration of medicine
3.3
19.7
107
366
N05BA12
ATC
alprazolam; oral
4.1
19.6
82
226
SPAT1309
SPAT
Guidance related to psychoactive substances / risk behaviour
7.0
19.6
49
75
WYA05
NOMESCO Finland
Emergency visit or other similar visit involving procedures
2.2
19.6
335
2184
N05BE01
ATC
buspirone; oral
9.8
18.9
38
41
IGV01
NOMESCO Finland
Psychiatric network contact
17.9
18.9
29
17
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
2.3
18.8
232
1289
F10.00
ICD-10 Finland
Alcohol-related acute intoxication uncomplicated
9.6
18.7
38
42
N06AX05
ATC
trazodone; oral
10.6
18.6
36
36
E950A
ICD-9 Finland
Suicide and self-inflicted poisoning by solid or liquid substances
18.3
18.4
28
16
2989X
ICD-9 Finland
Other nonorganic psychoses, Unspecified psychosis
26.0
18.4
25
10
R4160
NOMESCO Finland
Other therapy enhancing rehabilitation
9.2
18.2
38
44
F31.7
ICD-10 Finland
Bipolar affective disorder, currently in remission
8.6
18.0
39
48
F10.23
ICD-10 Finland
Alcohol dependence currently abstinent but using aversion-inducing or inhibitory medication
23.7
17.9
25
11
IFA01
NOMESCO Finland
Psychiatric pharmacotherapy plan, not specified
10.3
17.9
35
36
P76
ICPC
Depressive disorder
4.0
17.8
74
203
WX290
NOMESCO Finland
Other blockade of nerve
2.2
17.8
344
2326
C07AA05
ATC
propranolol; systemic
2.7
17.6
141
620
P03
ICPC
Feeling depressed
3.3
17.5
97
335
N05AF05
ATC
zuclopenthixol; systemic
21.7
17.4
25
12
F39
ICD-10 Finland
Unspecified mood [affective] disorder
9.1
17.2
36
42
J18.9
ICD-10 Finland
Pneumonia, unspecified
2.8
17.1
122
500
N03AF01
ATC
carbamazepine; oral, rectal
5.7
17.1
50
95
3018X
ICD-9 Finland
Personality disorders, Other personality disorders[MUU TAI SEKAMUOTOINEN PERSOONALLISUUSHÄIRIÖ]
26.5
17.0
23
9
F19.1
ICD-10 Finland
Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances, harmful use
14.6
17.0
28
20
3123D
ICD-9 Finland
Disturbance of conduct not elsewhere classified, Disorders of impulse control, not elsewhere classified[TOISTUVAT RAIVOKOHTAUKSET]
+∞
16.7
16
*
F10.09
ICD-10 Finland
Alcohol intoxication UNS
7.9
16.7
38
51
IBA04
NOMESCO Finland
Extensive initial psychiatric evaluation
10.5
16.6
32
32
F33.4
ICD-10 Finland
Recurrent depressive disorder, currently in remission
7.2
16.5
40
59
SPAT1307
SPAT
Psychosocial counselling and guidance
3.7
16.4
76
229
IBA01
NOMESCO Finland
Diagnostic and symptom-mapping evaluation
10.8
16.4
31
30
ICB02
NOMESCO Finland
Psychiatric treatment plan, extended/prolonged
15.9
16.3
26
17
V03AA01
ATC
NA
12.1
16.2
29
25
IAA01
NOMESCO Finland
Assessment of need for psychiatric treatment
6.2
15.9
43
74
F63.1
ICD-10 Finland
Pathological fire-setting [pyromania]
+∞
15.7
15
*
X78
ICD-10 Finland
Intentional self-harm by sharp object
19.9
15.7
23
12
Z63.0
ICD-10 Finland
Problems in relationship with spouse or partner
19.9
15.7
23
12
N06AA12
ATC
doxepin; systemic
6.9
15.7
39
60
N06AB05
ATC
paroxetine; oral
4.2
15.5
60
154
F42.1
ICD-10 Finland
Predominantly compulsive acts [obsessional rituals]
39.2
15.5
19
5
L03
ICPC
Low back symptom/complaint
2.4
15.4
149
721
N06CA01
ATC
amitriptyline and psycholeptics; systemic
4.0
15.3
64
176
N06AB08
ATC
fluvoxamine; oral
7.4
15.3
36
51
W0A12
NOMESCO Finland
Planned therapy visit for psychiatric disease
29.5
15.3
20
7
M79.6
ICD-10 Finland
Pain in limb
2.2
15.3
199
1113
F19.29
ICD-10 Finland
Addiction caused by several drugs in combination and by other psychoactive substances UNS
20.7
15.2
22
11
Z76.8
ICD-10 Finland
Persons encountering health services in other specified circumstances
5.2
15.1
47
96
F10.30
ICD-10 Finland
Withdrawal symptoms caused by alcohol uncomplicated
10.5
15.1
29
29
N06AX26
ATC
vortioxetine; oral
3.8
15.1
65
184
A10BA02
ATC
metformin; oral
2.5
14.9
128
579
SPAT1250
SPAT
Comprehensive monitoring of chronic illness
2.6
14.7
123
550
J44.8
ICD-10 Finland
Other specified chronic obstructive pulmonary disease
4.9
14.7
49
108
P80
ICPC
Personality disorder
+∞
14.6
14
*
IER04
NOMESCO Finland
Rehabilitative psychiatric group intervention, functional
13.0
14.5
25
20
F31.20
ICD-10 Finland
Bipolar disorder, manic episode with mood-congruent psychotic symptoms
13.0
14.5
25
20
N03AX16
ATC
pregabalin; oral
2.5
14.5
131
611
P16
ICPC
Acute alcohol abuse
8.3
14.2
31
39
F31
ICD-10 Finland
Bipolar affective disorder
9.2
14.1
29
33
F33.11
ICD-10 Finland
Recurrent depression, moderate episode of somatic syndrome
9.2
14.1
29
33
P06
ICPC
Sleep disturbance
3.2
14.1
78
268
SAA01
NOMESCO Finland
Simple examination of mouth
2.1
14.0
452
3593
F43.1
ICD-10 Finland
Post-traumatic stress disorder
6.4
13.9
36
59
S06.0
ICD-10 Finland
Concussion
2.9
13.8
88
335
WYA30
NOMESCO Finland
Preparations for expected poor cooperation
3.2
13.6
75
255
F60.6
ICD-10 Finland
Anxious [avoidant] personality disorder
+∞
13.6
13
*
SPAT1222
SPAT
Counselling/guidance promoting independent living
3.1
13.6
80
285
Z29
ICPC
Social problem NOS
8.0
13.5
30
39
SFC01
NOMESCO Finland
Adjuvant procedure of filling therapy
2.2
13.5
175
966
A01
ICPC
Pain general/multiple sites
4.1
13.4
53
139
N06BA04
ATC
methylphenidate; oral
5.4
13.1
39
76
N05AE04
ATC
ziprasidone; systemic
17.2
13.1
20
12
SPAT1301
SPAT
No procedures
2.1
13.0
179
1013
K04.4
ICD-10 Finland
Acute apical periodontitis of pulpal origin
3.0
13.0
78
284
SPAT1227
SPAT
Substance abuse rehabilitation
10.8
12.8
24
23
F20.09
ICD-10 Finland
Paranoid schizophrenia UNS
10.8
12.8
24
23
S29
ICPC
Skin symptom/complaint other
2.6
12.8
103
447
F32.1
ICD-10 Finland
Moderate depressive episode
3.6
12.8
59
177
F31.3
ICD-10 Finland
Bipolar affective disorder, current episode mild or moderate depression
12.6
12.7
22
18
3004A
ICD-9 Finland
Neurotic disorders, Neurotic depression
32.8
12.6
16
5
3123X
ICD-9 Finland
Disturbance of conduct not elsewhere classified, Disorders of impulse control, not elsewhere classified[TARKEMMIN MÄÄRITTELEMÄTÖN HILLITSEMISHÄIRIÖ]
+∞
12.5
12
*
N05AF01
ATC
flupentixol; systemic
13.6
12.5
21
16
N06AX21
ATC
duloxetine; oral
3.0
12.4
74
266
P74
ICPC
Anxiety disorder/anxiety state
4.2
12.4
47
119
A06AD11
ATC
lactulose; oral
3.1
12.3
70
246
R56.8
ICD-10 Finland
Other and unspecified convulsions
4.1
12.3
48
125
F20.5
ICD-10 Finland
Residual schizophrenia
38.4
12.3
15
*
N05AD03
ATC
melperone; systemic
16.3
12.2
19
12
F20.3
ICD-10 Finland
Undifferentiated schizophrenia
16.3
12.2
19
12
E66.8
ICD-10 Finland
Other obesity
4.2
12.2
46
116
Z76.9
ICD-10 Finland
Person encountering health services in unspecified circumstances
3.4
12.1
59
185
ICC04
NOMESCO Finland
Psychiatric treatment plan, permanent discontinuation
7.3
11.9
28
40
L17
ICPC
Foot/toe symptom/complaint
2.2
11.9
134
691
F32.3
ICD-10 Finland
Severe depressive episode with psychotic symptoms
6.9
11.9
29
44
N06AG02
ATC
moclobemide; oral
5.2
11.8
36
73
N07BA03
ATC
varenicline; oral
3.4
11.7
57
179
9691A
ICD-9 Finland
Poisoning by psychotropic agents, Phenothiazine-based tranquillisers
66.3
11.6
13
*
F19.21
ICD-10 Finland
Addiction caused by several drugs in combination and by other psychoactive substances currently independent but staying in a controlling environment
19.4
11.6
17
9
F60.5
ICD-10 Finland
Anankastic personality disorder
23.4
11.6
16
7
M54.5
ICD-10 Finland
Low back pain
2.0
11.6
200
1223
R11
ICD-10 Finland
Nausea and vomiting
3.3
11.6
59
192
F25.10
ICD-10 Finland
Schizoaffective syndrome, depressive type with only concomitant bipolar and schizophrenic symptoms
14.0
11.5
19
14
F25.00
ICD-10 Finland
Schizoaffective syndrome, manic type with only simultaneous bipolar and schizophrenic symptoms
12.1
11.4
20
17
SPAT1310
SPAT
Counselling related to known health issue
2.0
11.3
183
1092
X61
ICD-10 Finland
Intentional self-poisoning by and exposure to antiepileptic, sedative-hypnotic, antiparkinsonism and psychotropic drugs, not elsewhere classified
35.8
11.3
14
*
2961C
ICD-9 Finland
Affective psychoses, Manic disorder, recurrent episode[VAKAVA MASENNUSTILA,KESKIVAIKEA]
35.8
11.3
14
*
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
2.2
11.3
132
691
F25.20
ICD-10 Finland
Schizoaffective syndrome, mixed type with only concomitant bipolar and schizophrenic symptoms
17.5
11.2
17
10
SPAT1249
SPAT
Treatment-related counselling outside office
1.9
11.2
227
1468
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
2.4
11.2
101
464
188
Kela drug reimbursment
Psychosis requiring demanding treatment
13.0
11.2
19
15
P19
ICPC
Drug abuse
8.8
11.1
23
27
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.8
11.1
251
1687
SFA10
NOMESCO Finland
Fillning on one surface of tooth
1.8
11.1
335
2481
WZB00
NOMESCO Finland
Telephone receipt or other advice
1.9
11.0
200
1246
Z00.0
ICD-10 Finland
General medical examination
2.3
10.9
111
544
P28
ICPC
Limited function/disability (P)
15.9
10.9
17
11
EBA05
NOMESCO Finland
Complicated extraction of tooth
2.1
10.8
136
730
SFA20
NOMESCO Finland
Filling on two surfaces of tooth
1.8
10.8
360
2743
3050A
ICD-9 Finland
Nondependent abuse of drugs, Alcohol abuse
18.2
10.8
16
9
F31.1
ICD-10 Finland
Bipolar affective disorder, current episode manic without psychotic symptoms
13.2
10.7
18
14
E11.9
ICD-10 Finland
Type 2 diabetes mellitus, without complications
2.5
10.7
90
399
KMAK
NOMESCO Finland
NA
1.8
10.6
340
2550
K05.31
ICD-10 Finland
Periodontitis pronounced
3.1
10.6
59
203
E66.01
ICD-10 Finland
Obesity due to excess calories
2.9
10.5
66
249
F20.0
ICD-10 Finland
Paranoid schizophrenia
12.3
10.4
18
15
F41.00
ICD-10 Finland
Moderate panic disorder
6.2
10.4
27
45
AA400
NOMESCO Finland
Electroconvulsive therapy
16.4
10.4
16
10
C07AB07
ATC
bisoprolol; oral
1.9
10.4
184
1132
Z72.1
ICD-10 Finland
Alcohol use
9.8
10.3
20
21
Z72.8
ICD-10 Finland
Other problems related to lifestyle
19.2
10.3
15
8
SPAT1234
SPAT
Support of social functional capacity
4.6
10.3
35
80
F19.20
ICD-10 Finland
Addiction relationship caused by several drugs in combination and by other psychoactive substances currently independent
23.8
10.3
14
6
T74.1
ICD-10 Finland
Physical abuse
5.0
10.2
32
67
K08.3
ICD-10 Finland
Retained dental root
3.5
10.2
48
147
N05AL01
ATC
sulpiride; systemic
13.4
10.2
17
13
L28
ICPC
Limited function/disability (L)
2.8
10.2
66
251
B18.2
ICD-10 Finland
Chronic viral hepatitis C
8.1
10.2
22
28
K04.0
ICD-10 Finland
Pulpitis
2.4
10.1
88
398
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
2.1
10.1
133
725
F42.2
ICD-10 Finland
Mixed obsessional thoughts and acts
11.6
10.1
18
16
S10
ICPC
Boil/carbuncle
3.6
10.1
45
132
P01AB01
ATC
metronidazole; oral, rectal
1.9
10.1
203
1300
IEY01
NOMESCO Finland
Psychoeducation, individual
9.4
10.1
20
22
F32
ICD-10 Finland
Depressive episode
3.3
10.1
50
160
EBA15
NOMESCO Finland
Extraction of large number of teeth
5.2
10.0
30
60
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
3.3
10.0
50
161
K04.00
ICD-10 Finland
Hyperemia of pulp
3.6
9.9
45
134
IBZ02
NOMESCO Finland
Somatic assessment of psychiatric patient
17.1
9.9
15
9
F33.1
ICD-10 Finland
Recurrent depressive disorder, current episode moderate
4.7
9.9
33
74
F23.99
ICD-10 Finland
Acute and transient psychosis, unspecified UNS
26.5
9.8
13
5
IAB07
NOMESCO Finland
Consultation concerning a patient with self-harm intention
26.5
9.8
13
5
ICC01
NOMESCO Finland
Psychiatric treatment plan, transfer to psychiatric outpatient clinic
26.5
9.8
13
5
F20.04
ICD-10 Finland
Paranoid schizophrenia with partial recurrence
9.8
9.8
19
20
N03AX12
ATC
gabapentin; oral
2.5
9.8
82
361
F22.0
ICD-10 Finland
Delusional disorder
7.6
9.8
22
30
N02AX02
ATC
tramadol; systemic, rectal
1.8
9.8
206
1338
E66.9
ICD-10 Finland
Obesity, unspecified
4.4
9.8
34
80
AA1BG
NOMESCO Finland
Standard MRI examination of brain with high intensity magnet
2.9
9.7
61
229
Z71.8
ICD-10 Finland
Other specified counselling
2.0
9.7
151
881
F32.11
ICD-10 Finland
Moderate depressive episode with somatic syndrome
4.7
9.7
32
71
SPAT1312
SPAT
General health counselling
1.9
9.7
190
1203
SPAT1263
SPAT
Sampling
1.8
9.7
241
1654
N06AX22
ATC
agomelatine; oral
5.6
9.6
27
50
P18
ICPC
Medication abuse
11.6
9.6
17
15
F31.5
ICD-10 Finland
Bipolar affective disorder, current episode severe depression with psychotic symptoms
15.3
9.6
15
10
9694A
ICD-9 Finland
Poisoning by psychotropic agents, Benzodiazepine-based tranquillisers
15.3
9.6
15
10
N03AX11
ATC
topiramate; oral
5.1
9.5
29
59
F41.8
ICD-10 Finland
Other specified anxiety disorders
5.1
9.5
29
59
SGA02
NOMESCO Finland
Opening and dilatation of root canal of tooth
2.3
9.5
93
444
R05
ICPC
Cough
2.1
9.5
125
681
K08.1
ICD-10 Finland
Loss of teeth due to accident, extraction or local periodontal disease
3.1
9.5
53
182
AA1AD
NOMESCO Finland
CT of head and brain
2.2
9.5
104
526
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.8
9.5
194
1247
P04
ICPC
Feeling/behaving irritable/angry
17.9
9.4
14
8
29580
ICD-8 Finland
Schizophrenia, Other
30.6
9.4
12
*
T90
ICPC
Diabetes non-insulin dependent
2.3
9.4
93
448
F10.39
ICD-10 Finland
Withdrawal symptoms caused by alcohol UNS
8.2
9.4
20
25
F41.3
ICD-10 Finland
Other mixed anxiety disorders
7.1
9.4
22
32
R51.80
ICD-10 Finland
Headache
2.2
9.4
99
491
Z00.8
ICD-10 Finland
Other general examinations
2.8
9.4
59
222
F25.11
ICD-10 Finland
Schizoaffective syndrome, depressive type with prolonged schizophrenic than bipolar symptoms
22.1
9.4
13
6
30180
ICD-8 Finland
Personality disorders, Immatura
22.1
9.4
13
6
K92.0
ICD-10 Finland
Haematemesis
6.6
9.3
23
36
N05AX13
ATC
paliperidone; systemic
10.9
9.3
17
16
R10.1
ICD-10 Finland
Pain localized to upper abdomen
2.2
9.3
96
470
-1
NOMESCO Finland
NA
1.8
9.3
225
1523
R4140
NOMESCO Finland
Psychotherapy
14.0
9.2
15
11
SPAT1281
SPAT
Other administrative function
2.8
9.2
59
225
I63.9
ICD-10 Finland
Cerebral infarction, unspecified
3.9
9.2
37
100
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
1.9
9.1
148
873
F13.22
ICD-10 Finland
Addiction relationship caused by sedatives and hypnotics currently independent but uses substitute intermittent medication
15.9
9.1
14
9
215
Kela drug reimbursment
Diabetes, non-insulin-treated
2.1
9.0
112
594
N05AC02
ATC
thioridazine; oral
6.3
9.0
23
38
R07.4
ICD-10 Finland
Chest pain, unspecified
2.0
9.0
123
680
C03CA01
ATC
furosemide; systemic
2.3
9.0
85
401
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
2.8
8.9
57
218
N05AB01
ATC
dixyrazine; systemic
8.8
8.8
18
21
IER01
NOMESCO Finland
Psychoeducation, group
10.9
8.8
16
15
F20.39
ICD-10 Finland
Undifferentiated schizophrenia UNS
9.7
8.8
17
18
103
Kela drug reimbursment
Diabetes, insulin-treated
2.0
8.6
115
628
F20
ICD-10 Finland
Schizophrenia
11.8
8.6
15
13
N05CF02
ATC
zolpidem; oral
2.1
8.6
102
532
F05.9
ICD-10 Finland
Delirium, unspecified
9.2
8.6
17
19
SPAT1262
SPAT
Handing over of treatment supplies
2.3
8.6
83
396
SPAT1306
SPAT
Counselling and guidance related to nutrition and weight management
2.4
8.6
72
317
A28
ICPC
Limited function/disability NOS
2.9
8.6
51
186
SGA01
NOMESCO Finland
Tooth opening as first aid
2.0
8.6
124
702
SPAT1253
SPAT
Initiation, adjustment, discontinuation or repetition of medication
1.8
8.5
175
1116
F20.10
ICD-10 Finland
Raise schizophrenia continuously
28.0
8.5
11
*
W0A10
NOMESCO Finland
Mapping of psychosocial situation
28.0
8.5
11
*
N06AA06
ATC
trimipramine; systemic
7.5
8.5
19
26
N06AA09
ATC
amitriptyline; systemic
3.1
8.5
46
158
C10AA01
ATC
simvastatin; oral
1.9
8.4
133
775
2959A
ICD-9 Finland
Schizophrenic psychoses, Unspecified schizophrenia[ERILAISTUMATON SKITSOFRENIA,TARKEMMIN MÄÄRITTELEMÄT]
91.3
8.4
9
*
Z06
ICPC
Unemployment problem
13.0
8.4
14
11
F19.24
ICD-10 Finland
Addiction relationship caused by several drugs in combination and by other psychoactive substances active addiction
13.0
8.4
14
11
IEY08
NOMESCO Finland
Psychiatric coaching, domestic and community skills
13.0
8.4
14
11
G47.3
ICD-10 Finland
Sleep apnoea
2.0
8.4
117
651
J44.0
ICD-10 Finland
Chronic obstructive pulmonary disease with acute lower respiratory infection
5.7
8.4
23
42
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
2.0
8.4
115
636
G44.2
ICD-10 Finland
Tension-type headache
2.3
8.4
76
350
3049X
ICD-9 Finland
Drug dependence, Unspecified drug dependence
+∞
8.3
8
*
30188
ICD-8 Finland
Personality disorders, Alia definita
+∞
8.3
8
*
3123A
ICD-9 Finland
Disturbance of conduct not elsewhere classified, Disorders of impulse control, not elsewhere classified[PELIHIMO]
+∞
8.3
8
*
F63.2
ICD-10 Finland
Pathological stealing [kleptomania]
+∞
8.3
8
*
R53
ICD-10 Finland
Malaise and fatigue
2.0
8.3
110
600
Z72.2
ICD-10 Finland
Drug use
11.0
8.3
15
14
K10.3
ICD-10 Finland
Alveolitis of jaws
3.2
8.3
42
137
SPAT1217
SPAT
Assessment of need for services (elderly/care support)
6.2
8.2
21
35
M79.1
ICD-10 Finland
Myalgia
2.3
8.2
80
383
F13.25
ICD-10 Finland
Addiction caused by sedative and hypnotic continuous use
11.9
8.1
14
12
F93.89
ICD-10 Finland
Other childhood emotional disorders
11.9
8.1
14
12
F13.1
ICD-10 Finland
Mental and behavioural disorders due to use of sedatives or hypnotics, harmful use
33.8
8.1
10
*
F60.1
ICD-10 Finland
Schizoid personality disorder
33.8
8.1
10
*
F33.30
ICD-10 Finland
Recurrent depression, severe episode without somatic syndrome
10.2
8.1
15
15
Z91.5
ICD-10 Finland
Personal history of self-harm
22.4
8.0
11
5
F31.31
ICD-10 Finland
Bipolar disorder depressive episode with somatic syndrome
22.4
8.0
11
5
SPAT1216
SPAT
Assessment of functional ability
2.6
8.0
57
229
F43.22
ICD-10 Finland
Adaptation disorder with mixed anxiety and depression
3.3
8.0
39
124
R06.0
ICD-10 Finland
Dyspnoea
2.0
7.9
114
643
SPAT1294
SPAT
Other function in accordance with health social work nomenclature
6.2
7.9
20
33
K04.08
ICD-10 Finland
Other specified pulpit
2.5
7.8
59
247
SPAT1148
SPAT
Treatment of chronic ulcer or burn
2.5
7.8
59
248
F33.8
ICD-10 Finland
Other recurrent depressive disorders
15.3
7.7
12
8
F25.1
ICD-10 Finland
Schizoaffective disorder, depressive type
45.6
7.7
9
*
R52.9
ICD-10 Finland
Pain, unspecified
2.8
7.7
48
178
K59.09
ICD-10 Finland
Constipation, unspecified
3.9
7.7
30
80
N05AE05
ATC
lurasidone; oral
18.6
7.6
11
6
30041
ICD-8 Finland
Neuroses, Depressiva
18.6
7.6
11
6
IBA02
NOMESCO Finland
Evaluation of need for psychiatric rehabilitation
12.1
7.6
13
11
Z03
ICPC
Housing/neighbourhood problem
12.1
7.6
13
11
SGC10
NOMESCO Finland
Covering pulpa of tooth
2.2
7.6
76
367
3092E
ICD-9 Finland
Adjustment reaction, With predominant disturbance of other emotions[USEINA EMOTIONAALISINA OIREINA ILM.SOPEUTUMISHÄIRIÖ]
25.4
7.6
10
*
A02BX02
ATC
sucralfate; oral
5.9
7.6
20
35
SPAT1156
SPAT
Guidance concerning treatment of rash and skin
2.4
7.6
66
297
F10.9
ICD-10 Finland
Mental and behavioural disorders due to use of alcohol, Unspecified mental and behavioural disorder
10.2
7.6
14
14
T82
ICPC
Obesity
3.5
7.5
33
97
SPAT1251
SPAT
Organisation of medication
4.9
7.5
23
48
L16
ICPC
Ankle symptom/complaint
2.5
7.5
60
259
F32.8
ICD-10 Finland
Other depressive episodes
6.6
7.5
18
28
S18
ICPC
Laceration/cut
1.7
7.5
192
1304
2988A
ICD-9 Finland
Other nonorganic psychoses, Other and unspecified reactive psychosis
81.1
7.4
8
*
Z72.6
ICD-10 Finland
Gambling and betting
81.1
7.4
8
*
F43.29
ICD-10 Finland
Adaptation disorder UNS
5.7
7.4
20
36
K04.1
ICD-10 Finland
Necrosis of pulp
2.2
7.4
75
365
L02
ICPC
Back symptom/complaint
2.5
7.4
58
250
XF400
NOMESCO Finland
ECG with 12 standard connections
2.2
7.4
77
380
I10
ICD-10 Finland
Essential (primary) hypertension
1.7
7.4
198
1364
Z53.2
ICD-10 Finland
Procedure not carried out because of patient's decision for other and unspecified reasons
7.0
7.3
17
25
F40.01
ICD-10 Finland
Agoraphobia with concomitant panic disorder
11.0
7.3
13
12
E11
ICD-10 Finland
Type 2 diabetes mellitus
2.4
7.3
62
276
3041A
ICD-9 Finland
Drug dependence, Barbiturate and similarly acting sedative or hypnotic dependence
+∞
7.3
7
*
F12.24
ICD-10 Finland
Addiction caused by cannabis active addiction
+∞
7.3
7
*
A02BC02
ATC
pantoprazole; systemic
1.6
7.3
309
2397
SPAT1241
SPAT
Extensive assessment of psychosocial situation
6.4
7.3
18
29
SPAT1221
SPAT
Guidance concerning rehabilitation services and livelihood
5.6
7.3
20
37
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
2.4
7.3
64
290
F19.25
ICD-10 Finland
Addiction caused by several drugs in combination and by other psychoactive substances continuously used
16.0
7.2
11
7
A46
ICD-10 Finland
Erysipelas
2.3
7.2
64
291
L08
ICPC
Shoulder symptom/complaint
2.1
7.2
88
463
IBB01
NOMESCO Finland
Psychiatric functioning capacity evaluation
30.4
7.2
9
*
Z04.6
ICD-10 Finland
General psychiatric examination, requested by authority
30.4
7.2
9
*
3094A
ICD-9 Finland
Adjustment reaction, With mixed disturbance of emotions and conduct
30.4
7.2
9
*
3000A
ICD-9 Finland
Neurotic disorders, Anxiety states[TARKEMMIN MÄÄRITTELEMÄTÖN AHDISTUNEISUUSHÄIRIÖ]
30.4
7.2
9
*
IAB01
NOMESCO Finland
Psychiatric pharmacotherapy consultation
30.4
7.2
9
*
N05AC01
ATC
periciazine; systemic
20.3
7.2
10
5
IFA99
NOMESCO Finland
Other psychiatric pharmacotherapy service
8.1
7.1
15
19
Z08
ICPC
Social welfare problem
8.1
7.1
15
19
IBA03
NOMESCO Finland
Psychotherapy evaluation
8.1
7.1
15
19
Z46.3
ICD-10 Finland
Fitting and adjustment of dental prosthetic device
12.2
7.1
12
10
F13.29
ICD-10 Finland
Addiction caused by sedative and hypnotic UNS
12.2
7.1
12
10
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
3.0
7.1
40
140
F10.2
ICD-10 Finland
Mental and behavioural disorders due to use of alcohol, Dependence syndrome
10.2
7.1
13
13
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.8
7.0
125
758
L12
ICPC
Hand/finger symptom/complaint
2.1
7.0
83
433
SPAT1260
SPAT
Consultation of another employee
2.0
6.9
90
485
R95
ICPC
Chron obstructive pulmonary disease
7.7
6.9
15
20
NH1AA
NOMESCO Finland
Ankle X-ray examination without contrast
2.8
6.9
44
167
F92.9
ICD-10 Finland
Mixed disorder of conduct and emotions, unspecified
14.0
6.9
11
8
F23.3
ICD-10 Finland
Other acute predominantly delusional psychotic disorders
14.0
6.9
11
8
C03EA01
ATC
hydrochlorothiazide and potassium-sparing agents; oral
2.7
6.9
44
168
SFA30
NOMESCO Finland
Filling on tree or more surfaces of tooth
1.6
6.9
221
1591
331
Kela drug reimbursment
Atomoxetine, dexamphetamine, guanfacine and lisdexamphetamine
8.4
6.9
14
17
IEV99
NOMESCO Finland
Other psychiatric network intervention
11.1
6.8
12
11
RT250
NOMESCO Finland
NA
16.9
6.8
10
6
F92.8
ICD-10 Finland
Other mixed disorders of conduct and emotions
16.9
6.8
10
6
F33.01
ICD-10 Finland
Recurrent depression, mild episode of somatic syndrome
16.9
6.8
10
6
Z63.8
ICD-10 Finland
Other specified problems related to primary support group
16.9
6.8
10
6
F10.40
ICD-10 Finland
Withdrawal symptoms and delirium caused by alcohol without seizures
7.3
6.7
15
21
D09
ICPC
Nausea
3.0
6.7
36
124
F13.24
ICD-10 Finland
Addiction relationship caused by sedative and hypnotic active addiction
22.8
6.7
9
*
N30.0
ICD-10 Finland
Acute cystitis
2.3
6.7
61
284
L29
ICPC
Musculoskeletal sympt/complt other
2.8
6.6
42
159
IER02
NOMESCO Finland
Dedicated profession-specific psychiatric intervention, group
12.4
6.6
11
9
IEY06
NOMESCO Finland
Psychiatric treatment and rehabilitation coaching
12.4
6.6
11
9
M54.9
ICD-10 Finland
Dorsalgia, unspecified
2.2
6.6
65
313
R96
ICPC
Asthma
2.7
6.6
43
168
SPAT1211
SPAT
Application of soft bandage
2.6
6.5
46
187
Z04.8
ICD-10 Finland
Examination and observation for other specified reasons
2.2
6.4
66
322
N05AX15
ATC
cariprazine; oral
70.6
6.4
7
*
Z63.9
ICD-10 Finland
Problem related to primary support group, unspecified
70.6
6.4
7
*
Z63.2
ICD-10 Finland
Inadequate family support
70.6
6.4
7
*
F91.0
ICD-10 Finland
Conduct disorder confined to the family context
70.6
6.4
7
*
F15.2
ICD-10 Finland
Mental and behavioural disorders due to use of other stimulants, including caffeine, dependence syndrome
14.5
6.4
10
7
IEY02
NOMESCO Finland
Intensified psychiatric outpatient care, Assertive Community Treatment (ACT)
14.5
6.4
10
7
IGY02
SPAT
NA
14.5
6.4
10
7
IFB01
NOMESCO Finland
Electroconvulsive Therapy (ECT)
14.5
6.4
10
7
A29
ICPC
General symptom/complaint other
2.3
6.4
56
253
A02BC01
ATC
omeprazole; systemic
1.8
6.4
123
761
S21
ICPC
Skin texture symptom/complaint
2.2
6.4
61
289
J44.9
ICD-10 Finland
Chronic obstructive pulmonary disease, unspecified
5.3
6.4
18
35
K59.0
ICD-10 Finland
Constipation
3.4
6.4
29
89
IDY03
NOMESCO Finland
Systematic individual therapy, cognitive-behavioural
3.9
6.3
24
63
P27
ICPC
Fear of mental disorder
5.6
6.3
17
31
N05CD02
ATC
nitrazepam; oral
11.2
6.3
11
10
WZC00
NOMESCO Finland
Planning of intervention or health care consultation
1.6
6.3
175
1207
F13.20
ICD-10 Finland
Addiction relationship caused by sedatives and hypnotics currently independent
18.2
6.3
9
5
F17.20
ICD-10 Finland
Addiction relationship caused by tobacco addiction relationship currently independent
18.2
6.3
9
5
N06BA09
ATC
atomoxetine; oral
18.2
6.3
9
5
Z02.7
ICD-10 Finland
Issue of medical certificate
2.7
6.3
41
160
3138C
ICD-9 Finland
Disturbance of emotions specific to childhood and adolescence, Other or mixed emotional disturbances of childhood or adolescence[LAPSUUSIÄN RAJATILAHÄIRIÖ]
+∞
6.3
6
*
F60.7
ICD-10 Finland
Dependent personality disorder
+∞
6.3
6
*
RT120
NOMESCO Finland
NA
+∞
6.3
6
*
J01DB01
ATC
cefalexin; oral
1.6
6.3
452
3932
L02.9
ICD-10 Finland
Cutaneous abscess, furuncle and carbuncle, unspecified
4.0
6.2
23
59
SPAT1033
SPAT
Irrigation or wax removal of outer auditory canal
2.1
6.2
69
348
L86
ICPC
Back syndrome with radiating pain
3.2
6.2
31
102
M03BC01
ATC
orphenadrine (citrate); systemic
1.7
6.2
135
870
NA1AD
NOMESCO Finland
Cervical spine CT examination
3.4
6.2
28
86
A05
ICPC
Feeling ill
2.4
6.2
49
211
R41.8
ICD-10 Finland
Other and unspecified symptoms and signs involving cognitive functions and awareness
2.9
6.1
35
124
R42
ICD-10 Finland
Dizziness and giddiness
2.0
6.1
82
445
F17.29
ICD-10 Finland
Addiction caused by tobacco UNS
5.0
6.1
18
37
P17
ICPC
Tobacco abuse
5.0
6.1
18
37
SPAT1059
SPAT
Spirometry at the office
3.2
6.1
30
98
T51.0
ICD-10 Finland
Toxic effect: Ethanol
8.7
6.1
12
14
F28
ICD-10 Finland
Other nonorganic psychotic disorders
10.2
6.1
11
11
Z71.2
ICD-10 Finland
Person consulting for explanation of investigation findings
1.8
6.0
115
709
SPAT1305
SPAT
Counselling and guidance related to physical exercise
2.5
6.0
46
196

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
129
185
8.49
88.93
4.2
3.2
—
—
—
0
0
73
80
10.18
61.59
6.8
5.3
396.5
365.6
umol/l
0.77
65
71
133
302
5.30
56.95
6.2
2.9
—
—
—
0
0
145
362
4.89
55.40
4.2
2.3
—
—
—
0
0
155
438
4.36
50.26
4.1
2.1
—
—
—
0
0
157
477
4.04
45.79
4.1
2.1
—
—
—
0
0
156
479
3.99
44.75
4.1
2.1
—
—
—
0
0
156
481
3.97
44.46
4.2
2.1
—
—
—
0
0
47
46
10.95
42.68
2.5
1.7
—
—
—
0
0
149
473
3.81
40.43
3.2
2.1
—
—
—
0
0
267
1280
2.87
35.73
4.2
3.3
8.7
9.0
mmol/l
0.26
231
1120
507
3449
3.30
34.09
7.8
7.3
77.6
75.5
u/l
0.59
477
3284
29
21
14.42
31.54
2.6
1.7
131.7
139.4
umol/l
—
12
9
372
2209
2.64
31.36
5.7
6.5
9.2
11.4
umol/l
5.51
347
2102
517
3667
3.18
30.05
4.8
3.6
14.3
14.6
pmol/l
1.76
476
3412
324
1869
2.49
28.02
4.9
7.1
1.2
1.2
mmol/l
0.68
274
1618
297
1659
2.48
27.39
4.6
6.2
1.2
1.2
mmol/l
0.10
278
1542
610
4938
6.55
26.27
16.1
11.3
139.6
139.6
mmol/l
0.04
595
4812
264
1429
2.45
25.71
1.9
1.7
94.9
97.2
pmol/l
0.31
147
777
242
1260
2.48
25.66
2.6
3.3
2.4
2.4
mmol/l
0.03
217
1148
392
2531
2.43
25.52
5.0
4.7
6.7
6.5
mmol/l
0.63
368
2332
204
987
2.57
25.23
4.0
3.0
1.0
1.0
kg/l
0.07
20
136
609
4960
6.18
25.15
16.4
11.3
3.9
4.0
mmol/l
1.82
593
4820
131
515
2.94
24.20
1.8
1.6
1028.6
1167.9
nmol/l
1.01
102
408
566
4457
3.42
23.00
6.0
4.1
1.8
2.3
mu/l
0.76
531
4193
284
1654
2.29
22.69
4.0
5.4
36.8
37.2
g/l
0.56
262
1572
248
1366
2.34
22.58
3.1
2.6
50.0
56.7
u/l
2.71
231
1291
158
716
2.60
22.02
1.7
1.6
403.1
21151285.0
pmol/l
0.80
136
643
220
1167
2.35
21.70
2.7
2.1
286.7
333.6
u/l
0.18
211
1116
210
1106
2.34
20.93
3.2
3.9
7.4
7.4
ph
0.45
44
191
59
152
4.18
20.93
1.7
1.2
—
—
—
0
0
397
2787
2.13
18.39
16.3
9.5
4.6
4.0
e9/l
3.97
330
2452
157
776
2.36
17.74
1.6
1.4
16.3
20.0
nmol/l
3.10
139
694
426
3108
2.12
17.34
3.8
3.0
—
—
—
0
0
187
1020
2.18
16.53
3.9
4.1
—
—
—
0
0
393
2841
2.00
15.66
4.8
3.5
85.8
599.4
e6/l
0.64
12
32
249
1544
2.01
15.41
6.8
6.2
—
—
—
0
0
556
4625
2.59
14.90
5.2
3.4
6.1
5.8
mmol/l
3.99
521
4341
344
2425
1.91
14.21
8.1
6.3
0.0
0.0
e9/l
0.76
283
2148
352
2503
1.91
14.13
9.1
6.6
0.2
0.2
e9/l
0.56
295
2239
155
832
2.14
13.99
2.2
2.3
7.6
5.7
e6/l
0.64
141
733
343
2424
1.90
13.98
8.1
6.2
0.6
0.6
e9/l
2.89
280
2143
26
47
5.72
13.94
1.9
1.3
1.8
1.3
promille
0.77
20
37
149
803
2.12
13.24
2.1
2.4
534.5
583.0
mosm/kgh2o
1.46
135
676
352
2540
1.86
13.12
8.1
6.2
2.5
1.9
e9/l
0.89
299
2286
111
534
2.31
13.05
2.4
3.1
7.1
8.5
umol/l
0.25
86
464
233
1477
1.91
13.04
5.9
6.3
1.0
1.1
inr
3.74
84
464
206
1260
1.94
12.80
2.8
2.8
20.0
61.9
e6/l
2.49
160
944
119
595
2.23
12.74
2.4
2.9
2.4
2.4
mmol/l
0.02
96
521
233
1489
1.89
12.64
3.7
2.9
21.8
42.2
ng/l
1.11
136
800
269
1803
1.85
12.53
2.4
2.3
68.4
72.3
nmol/l
1.08
247
1685
588
5129
2.90
12.43
16.1
10.9
20.4
21.8
mg/l
0.49
495
3877
188
1130
1.94
12.21
2.8
2.7
0.5
0.3
e6/l
0.48
146
825
171
995
1.98
12.21
3.7
3.0
—
—
—
0
0
177
1052
1.95
11.83
3.7
4.3
8.0
11.5
mg/mmol
0.58
107
730
188
1144
1.91
11.69
2.8
2.6
—
—
—
0
0
232
1513
1.84
11.60
3.4
3.2
50.0
88.3
e6/l
0.40
171
1023
169
1004
1.93
11.24
3.0
3.5
54.1
331.9
mg/l
1.44
109
693
517
4322
2.04
11.24
6.2
4.4
40.3
38.5
mmol/mol
2.61
477
4134
16
8
20.47
11.17
1.4
2.8
—
—
—
0
0
60
233
2.74
11.05
2.8
3.2
7.4
7.4
ph
0.21
13
23
83
378
2.37
10.99
5.3
10.2
1.0
1.0
mmol/l
0.07
68
301
306
2198
1.75
10.84
7.5
6.3
0.6
0.7
%
1.18
281
2089
30
77
4.04
10.68
1.9
2.0
—
—
—
0
0
314
2279
1.75
10.66
7.9
6.2
2.5
2.9
%
3.06
283
2157
78
351
2.39
10.60
2.1
3.9
1.1
1.4
mmol/l
0.35
62
278
184
1144
1.86
10.55
12.2
6.7
—
—
—
0
0
315
2293
1.74
10.55
8.5
6.4
8.1
8.4
%
1.66
292
2192
433
3451
1.80
10.50
4.1
3.6
10.3
8.6
mm/h
2.21
403
3247
17
27
6.44
10.32
3.9
2.9
—
—
—
0
0
159
952
1.89
10.22
2.9
2.4
—
—
—
0
0
402
3151
1.75
10.17
4.1
3.6
—
—
—
0
0
78
360
2.33
10.00
2.2
3.9
—
—
—
0
0
117
635
2.03
9.99
3.1
3.7
0.8
0.8
mmol/l
0.40
107
610
325
2410
1.71
9.99
7.9
6.0
29.3
29.3
%
0.02
300
2297
322
2384
1.71
9.93
7.7
5.9
57.4
56.4
%
0.76
298
2280
151
899
1.89
9.83
2.4
2.0
3.2
2.7
mg/l
1.41
124
782
77
357
2.32
9.77
2.2
3.9
5.9
5.8
kpa
0.38
70
347
81
385
2.26
9.70
5.1
10.0
11.5
13.4
kpa
2.90
76
367
11
11
10.16
9.56
2.2
2.6
14.1
19.9
umol/l
0.50
11
11
294
2149
1.68
9.32
12.1
8.4
0.0
0.0
e9/l
0.62
227
1774
180
1154
1.78
9.15
1.7
1.7
1.9
1.4
mmol/l
3.15
151
1021
604
5487
2.95
9.07
12.8
8.6
31.2
30.4
u/l
0.37
586
5355
97
509
2.07
9.03
3.1
6.9
1.0
1.0
mmol/l
0.21
91
483
181
1166
1.77
9.03
4.1
3.1
0.0
0.0
estimate
1.08
63
440
176
1125
1.78
9.02
4.5
3.9
96.6
93.8
%
0.90
171
1105
71
329
2.30
9.01
3.5
3.2
1.6
1.7
%
0.32
58
301
22
51
4.43
8.93
1.8
2.1
—
—
—
0
0
97
516
2.04
8.70
1.9
1.6
—
—
—
0
0
188
1254
1.71
8.17
1.3
1.3
3.1
1.5
u/ml
0.47
44
352
26
74
3.62
8.05
1.8
2.2
140.1
134.5
g/l
0.45
20
50
65
307
2.24
7.89
2.2
2.5
1065.7
3905.3
u/l
1.21
21
132
121
731
1.81
7.35
3.8
3.2
239.2
664.5
ng/l
0.81
83
474
11
7
15.95
7.25
2.3
1.1
—
—
—
0
0
299
2292
1.57
7.22
3.6
3.0
0.0
0.0
estimate
0.49
63
417
44
938
0.43
7.08
1.2
1.3
—
—
—
0
0
147
950
1.71
7.05
3.6
3.0
—
—
—
0
0
81
437
1.98
6.95
2.6
2.8
35.6
154.8
u/l
0.56
65
373
295
2271
1.56
6.89
4.6
4.1
0.0
0.0
estimate
0.50
67
454
60
290
2.18
6.89
1.6
1.5
336.5
283.0
mu/l
0.46
52
257
294
2269
1.55
6.75
3.6
2.9
0.0
0.0
estimate
0.00
63
435
21
62
3.47
6.19
2.0
2.1
17.5
17.4
%
0.01
15
27
93
546
1.82
6.17
1.4
1.6
—
—
—
0
0
54
263
2.15
6.10
2.8
3.6
1.2
1.2
mmol/l
0.89
49
235
46
212
2.26
5.94
4.2
7.0
—
—
—
0
0
67
368
1.92
5.46
8.0
16.7
1.2
1.2
inr
—
9
66
103
647
1.71
5.40
2.5
2.5
3.6
2.1
e6/l
0.95
48
327
29
113
2.64
5.37
1.7
1.5
251.5
293.7
ug/g
0.36
17
61
36
157
2.37
5.29
1.4
1.2
—
—
—
0
0
11
22
5.07
5.28
1.0
1.4
126.6
151.3
nmol/l
0.72
11
22
153
1072
1.56
5.17
2.2
1.7
0.9
1.0
mg/l
0.20
106
764
43
207
2.16
5.03
2.1
2.7
71.4
109.3
ng/l
0.80
37
177
61
335
1.91
4.98
5.4
9.1
—
—
—
0
0
45
222
2.11
4.95
2.8
3.4
64.4
70.3
e9/l
0.53
28
154
38
175
2.25
4.95
1.4
1.8
—
—
—
0
0
96
606
1.69
4.94
1.8
2.1
—
—
—
0
0
125
845
1.60
4.91
1.7
1.7
—
—
—
0
0
53
279
1.98
4.90
2.4
2.2
6.0
9.5
ug/l
0.90
47
257
64
360
1.86
4.86
2.4
2.6
0.2
0.2
g/l
0.24
56
340
22
531
0.39
4.73
1.2
1.4
—
—
—
0
0
157
1129
1.52
4.67
1.4
1.4
2.1
2.3
g/l
0.92
85
746
41
202
2.10
4.54
2.1
3.8
23.6
23.8
mmol/l
0.14
36
192
22
82
2.74
4.46
2.0
1.8
1.8
2.5
mmol/l
0.79
16
49
549
5046
1.64
4.44
5.0
3.8
2.9
2.9
mmol/l
0.18
510
4788
83
526
1.66
4.20
1.7
2.3
2.6
2.4
g/l
2.45
73
494
52
290
1.86
4.08
1.3
1.2
—
—
—
0
0
543
5004
1.58
4.04
4.5
3.6
4.6
4.8
mmol/l
1.88
510
4784
85
549
1.63
4.00
1.4
1.2
—
—
—
0
0
57
934
0.57
3.99
1.5
1.4
—
—
—
0
0
72
446
1.69
3.98
1.2
1.1
—
—
—
0
0
38
192
2.04
3.96
6.7
13.5
—
—
—
0
0
66
400
1.73
3.94
3.8
3.2
—
—
—
0
0
23
94
2.50
3.92
2.3
1.4
—
—
—
0
0
266
2176
1.38
3.83
2.8
2.6
87.1
115.0
ug/l
2.69
236
2073
51
291
1.82
3.74
1.4
1.4
—
—
—
0
0
177
2235
0.71
3.59
3.0
2.3
—
—
—
0
0
30
147
2.09
3.42
1.2
1.3
—
—
—
0
0
56
340
1.71
3.35
4.3
4.4
1.0
0.5
%
—
9
75
521
4810
1.46
3.32
4.1
3.3
1.6
1.3
mmol/l
9.76
482
4583
61
380
1.67
3.32
1.3
1.3
163.7
139.5
iu/ml
0.16
18
148
536
4979
1.48
3.28
4.5
3.6
1.3
1.4
mmol/l
14.99
497
4752
59
367
1.67
3.23
4.4
4.6
1.1
0.9
%
0.21
17
105
56
346
1.68
3.15
4.6
4.8
0.2
0.2
%
0.04
17
94
581
5503
1.63
3.12
14.5
9.6
—
—
—
0
0
51
308
1.71
3.12
2.6
3.7
4.6
4.7
pmol/l
0.27
44
281
53
326
1.68
3.04
4.7
4.9
0.1
0.1
%
—
10
77
81
554
1.53
3.01
1.3
1.6
—
—
—
0
0
32
172
1.91
2.86
3.4
3.5
—
—
—
0
0
20
402
0.48
2.74
1.2
1.6
—
—
—
0
0
10
32
3.16
2.65
1.4
1.1
—
—
—
0
0
11
38
2.93
2.59
1.9
2.4
—
—
—
0
0
615
5957
1.94
2.48
27.6
15.5
263.0
253.1
e9/l
3.53
601
5840
81
578
1.46
2.47
1.8
2.3
13.9
14.8
umol/l
0.40
75
546
191
1570
1.31
2.45
2.2
2.0
—
—
—
0
0
7
192
0.36
2.44
1.6
1.4
—
—
—
0
0
7
193
0.36
2.43
1.6
1.4
—
—
—
0
0
25
132
1.93
2.39
4.7
4.6
—
—
—
0
0
6
13
4.65
2.27
1.8
1.1
14.8
17.4
umol/l
—
6
13
615
5969
1.88
2.27
27.5
15.3
30.1
30.2
pg
0.46
609
5910
615
5969
1.88
2.27
27.5
15.4
90.0
89.8
fl
0.48
609
5911
615
5970
1.87
2.25
27.6
15.4
4.7
4.7
e12/l
0.34
599
5843
8
197
0.40
2.20
1.5
1.4
—
—
—
0
0
615
5973
1.86
2.20
27.8
15.5
140.7
140.6
g/l
0.03
609
5911
615
5973
1.86
2.20
27.7
15.5
7.6
6.6
e9/l
6.95
600
5847
50
331
1.55
2.19
2.6
4.3
—
—
—
0
0
29
166
1.78
2.19
2.2
2.1
—
—
—
0
0
82
602
1.42
2.17
2.5
2.2
13.7
14.8
nmol/l
0.53
75
562
21
110
1.94
2.08
2.1
1.7
2.5
10.2
e6/l
1.42
16
91
5
10
5.03
2.07
2.4
1.3
1.2
1.2
mmol/l
—
5
10
45
295
1.57
2.07
1.3
1.2
—
—
—
0
0
33
201
1.68
2.03
2.1
2.4
0.1
0.1
e6/l
0.03
33
194
28
164
1.74
1.98
1.1
1.2
—
—
—
0
0
19
98
1.97
1.97
2.3
1.8
—
—
—
0
0
5
11
4.57
1.94
1.6
5.8
24.2
24.9
mmol/l
—
5
11
38
244
1.59
1.92
3.0
2.3
—
—
—
0
0
67
486
1.42
1.91
1.7
2.4
22.1
25.3
%
1.03
58
433
21
115
1.85
1.85
1.9
3.5
—
—
—
0
0
129
1044
1.30
1.83
2.4
2.2
—
—
—
0
0
5
135
0.37
1.77
1.2
1.6
—
—
—
0
0
145
1197
1.27
1.76
1.7
1.7
—
—
—
0
0
6
18
3.35
1.75
1.0
1.4
—
—
—
0
0
98
773
1.32
1.68
2.1
2.6
97.2
124.8
ug/g
0.75
68
634
162
1363
1.25
1.67
2.8
2.2
—
—
—
0
0
6
146
0.41
1.66
1.0
1.1
—
—
—
0
0
6
146
0.41
1.66
1.0
1.1
—
—
—
0
0
49
345
1.46
1.65
1.2
1.3
201.3
269.2
u/ml
0.37
44
316
7
25
2.82
1.65
1.4
1.2
5.6
6.2
mmol/l
—
7
25
203
1756
1.23
1.62
1.8
1.9
—
—
—
0
0
11
50
2.22
1.57
1.4
1.5
—
—
—
0
0
17
92
1.87
1.57
9.5
4.1
12.6
28.1
mg/l
—
9
62
44
308
1.46
1.54
2.8
5.3
4.3
29.9
ug/l
0.94
34
252
7
27
2.61
1.52
1.4
2.6
29.3
32.6
pg
—
7
27
11
51
2.18
1.51
1.5
1.5
—
—
nmol/l
—
0
0
146
1230
1.24
1.48
6.7
4.5
—
—
—
0
0
18
103
1.77
1.42
1.1
1.1
—
—
—
0
0
162
1389
1.22
1.40
3.1
2.6
—
—
—
0
0
24
150
1.62
1.40
1.1
1.1
—
—
—
0
0
130
1089
1.24
1.39
2.1
2.4
3488.8
4436.2
umol/l
0.11
106
993
16
89
1.82
1.38
1.7
3.0
—
—
—
0
0
100
814
1.27
1.37
1.2
1.3
13.0
23.4
iu/ml
2.11
24
262
40
283
1.44
1.35
3.5
3.2
—
—
—
0
0
9
43
2.11
1.30
1.9
1.3
—
—
—
0
0
9
43
2.11
1.30
2.7
3.7
—
—
—
0
0
12
62
1.95
1.28
1.2
3.0
1.3
1.4
%
—
6
49
17
99
1.74
1.28
1.6
2.6
174.7
116.2
ug/min
0.24
12
59
14
77
1.84
1.26
2.1
3.8
—
—
—
0
0
6
25
2.41
1.24
1.5
2.2
12.3
29.1
ug/l
—
6
25
10
50
2.02
1.17
1.2
1.6
—
—
—
0
0
5
20
2.51
1.15
1.6
4.7
—
—
—
0
0
5
20
2.51
1.15
1.8
2.1
29.0
27.3
umol/l
—
5
20
8
40
2.01
1.12
1.5
2.4
—
—
—
0
0
8
40
2.01
1.12
1.5
2.4
106.4
106.2
mmol/l
—
8
40
8
40
2.01
1.12
1.5
2.4
3.9
4.0
mmol/l
—
8
40
8
40
2.01
1.12
1.4
1.8
14.4
11.2
umol/l
—
8
40
7
31
2.27
1.10
2.9
2.0
—
—
—
0
0
7
31
2.27
1.10
1.0
1.1
—
—
—
0
0
5
21
2.39
1.09
1.4
1.4
—
—
—
0
0
7
33
2.13
1.06
1.0
1.2
—
—
—
0
0
235
2132
1.16
1.05
4.0
3.9
—
—
—
0
0
86
713
1.24
1.03
1.3
1.4
226.7
444.7
titre
—
9
135
15
91
1.66
1.01
1.4
1.3
7.3
4.3
u/ml
—
6
41
9
48
1.89
1.00
3.3
2.5
—
—
—
0
0
0
30
0.00
0.97
0.0
1.0
—
4.2
—
0
5
0
31
0.00
0.96
0.0
1.1
—
—
—
0
0
24
167
1.45
0.93
1.5
1.5
—
—
—
0
0
25
177
1.43
0.89
2.0
2.1
—
—
—
0
0
8
42
1.92
0.89
3.3
3.4
48.6
41.8
mu/l
—
8
42
17
111
1.55
0.88
1.8
2.0
—
—
—
0
0
8
43
1.87
0.87
1.8
2.0
—
—
—
0
0
8
43
1.87
0.87
1.8
2.0
—
—
—
0
0
8
43
1.87
0.87
1.8
2.0
—
—
—
0
0
8
43
1.87
0.87
1.8
2.0
—
—
—
0
0
6
31
1.94
0.84
3.7
2.9
—
—
—
0
0
32
244
1.33
0.77
1.8
4.8
79.2
79.4
ng/l
0.00
27
229
20
276
0.72
0.73
1.3
1.3
—
—
—
0
0
5
25
2.01
0.73
1.2
3.0
—
—
—
0
0
10
60
1.68
0.72
3.1
2.4
—
—
—
0
0
5
26
1.93
0.70
1.4
1.1
—
—
—
0
0
88
764
1.18
0.70
1.2
1.3
1.5
7.0
u/ml
3.63
28
332
13
190
0.68
0.66
1.6
2.2
24.0
36.1
u/ml
0.55
13
183
42
342
1.24
0.64
3.6
2.4
5.6
4.1
e9/l
2.51
33
299
25
324
0.76
0.63
1.2
1.4
—
—
—
0
0
67
574
1.19
0.63
1.6
1.8
—
—
—
0
0
12
79
1.53
0.63
4.3
4.1
53.0
56.6
%
0.48
12
79
0
22
0.00
0.59
0.0
4.6
—
—
—
0
0
19
140
1.37
0.59
1.5
1.9
2.7
6.0
iu/l
—
9
53
37
301
1.24
0.58
1.4
1.4
16.6
20.6
iu/l
0.51
29
256
6
35
1.72
0.58
1.3
3.3
12.1
12.8
%
—
6
35
5
89
0.56
0.56
1.0
1.3
—
—
—
0
0
6
37
1.63
0.55
1.3
1.5
—
67.6
—
0
7
31
249
1.26
0.55
1.4
1.4
4.8
7.7
u/l
2.52
23
206
14
99
1.42
0.54
1.1
1.1
—
—
—
0
0
58
499
1.18
0.54
1.3
1.4
—
—
—
0
0
28
346
0.80
0.51
1.3
1.2
—
36.3
—
0
17
61
530
1.17
0.51
1.3
1.2
—
—
—
0
0
9
65
1.39
0.50
1.4
2.6
—
—
—
0
0
10
144
0.69
0.49
1.0
1.1
0.2
1.9
u/ml
—
5
64
15
110
1.37
0.49
1.1
1.1
—
—
—
0
0
7
47
1.49
0.47
1.3
1.5
—
—
—
0
0
7
49
1.43
0.46
3.3
1.4
—
—
—
0
0
5
83
0.60
0.46
2.6
4.0
3.5
3.9
u/ml
—
5
76
26
212
1.24
0.43
1.3
1.6
—
6.8
—
0
13
145
1349
1.10
0.42
3.3
3.3
1.4
1.7
ug/l
0.72
134
1250
6
94
0.63
0.42
2.2
2.6
—
—
—
0
0
0
15
0.00
0.41
0.0
1.1
—
0.7
—
0
9
0
16
0.00
0.41
0.0
1.2
—
—
—
0
0
0
17
0.00
0.40
0.0
1.1
—
—
—
0
0
36
307
1.18
0.39
1.1
1.1
—
—
—
0
0
0
19
0.00
0.39
0.0
1.4
—
—
—
0
0
19
154
1.24
0.34
2.0
3.8
0.3
0.3
g/l
0.09
13
73
6
45
1.34
0.34
1.2
1.2
—
—
—
0
0
35
303
1.16
0.33
1.9
1.7
37.9
38.1
nmol/l
0.02
35
297
13
166
0.78
0.33
1.1
1.1
0.5
2.2
u/ml
—
5
69
525
5170
1.09
0.33
19.7
11.1
41.6
41.6
%
0.03
377
4351
10
74
1.36
0.32
1.8
1.7
—
—
—
0
0
12
154
0.77
0.32
9.1
7.8
—
—
—
0
0
44
390
1.14
0.31
3.5
2.6
10.0
10.5
g/l
0.37
36
356
7
54
1.30
0.30
1.6
1.4
—
—
—
0
0
10
129
0.77
0.28
1.1
1.2
—
2.9
—
0
12
12
150
0.80
0.27
1.0
1.1
11.0
8.7
u/ml
—
7
88
13
105
1.24
0.25
1.0
1.1
—
—
—
0
0
10
78
1.29
0.24
4.8
3.6
4.1
4.2
e9/l
—
10
78
12
147
0.81
0.23
1.3
1.5
—
—
—
0
0
5
38
1.32
0.23
1.4
1.3
—
—
—
0
0
5
41
1.22
0.22
1.0
1.0
—
—
—
0
0
0
11
0.00
0.21
0.0
5.5
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
12
0.00
0.21
0.0
2.0
—
5.4
—
0
12
0
12
0.00
0.21
0.0
1.2
—
55.3
—
0
12
0
12
0.00
0.21
0.0
2.2
—
—
—
0
0
0
12
0.00
0.21
0.0
1.3
—
—
—
0
0
0
12
0.00
0.21
0.0
2.0
—
2.5
—
0
12
11
134
0.82
0.21
3.8
4.8
544.0
677.8
u/ml
0.07
11
117
25
281
0.89
0.20
1.0
1.1
—
—
—
0
0
13
152
0.85
0.17
1.2
1.4
194.7
209.9
u/ml
—
6
96
56
597
0.93
0.17
1.5
1.4
—
—
—
0
0
18
158
1.14
0.16
2.2
2.8
—
—
—
0
0
76
795
0.95
0.13
1.9
2.3
0.5
0.6
ug/l
1.83
54
402
15
168
0.89
0.12
1.1
1.1
—
—
—
0
0
11
95
1.16
0.11
1.4
1.2
—
—
—
0
0
156
1595
0.97
0.10
1.5
1.6
—
—
—
0
0
8
75
1.07
0.07
1.8
1.7
—
—
—
0
0
8
95
0.84
0.06
1.3
1.2
—
—
—
0
0
10
90
1.11
0.05
1.3
1.1
—
—
—
0
0
89
902
0.98
0.03
2.0
1.8
—
—
—
0
0
0
8
0.00
0.00
0.0
3.6
—
326.6
—
0
8
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
0.00
0.0
1.1
—
—
—
0
0
0
9
0.00
0.00
0.0
1.7
—
—
—
0
0
0
9
0.00
0.00
0.0
1.2
—
1.8
—
0
9
5
50
1.00
0.00
2.4
3.2
35.8
31.2
u/ml
—
5
50
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
0
9
0.00
0.00
0.0
1.2
—
—
—
0
0
0
8
0.00
0.00
0.0
1.5
—
—
—
0
0
0
6
0.00
0.00
0.0
1.3
—
—
—
0
0
0
9
0.00
0.00
0.0
1.1
—
—
—
0
0
0
5
0.00
0.00
0.0
1.8
—
—
—
0
0
8
82
0.98
0.00
1.1
1.5
—
—
—
0
0
0
8
0.00
0.00
0.0
7.8
—
—
—
0
0
0
8
0.00
0.00
0.0
5.6
—
1.3
—
0
8
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
0.00
0.0
2.6
—
194.6
—
0
5
8
80
1.00
0.00
1.5
1.2
—
—
—
0
0
0
6
0.00
0.00
0.0
2.2
—
3.6
—
0
6

Mortality – FinRegistry

Association

Association between endpoint F5_HABIT and mortality.

Females

Parameter HR [95% CI] p-value
F5_HABIT 2.319 [1.81, 2.98] < 0.001
Birth year 0.991 [0.98, 1.0] 0.074

During the follow-up period (1.1.1998 — 31.12.2019), 179 out of 1743 females with F5_HABIT died.

Males

Parameter HR [95% CI] p-value
F5_HABIT 2.676 [2.17, 3.3] < 0.001
Birth year 0.987 [0.98, 1.0] 0.008

During the follow-up period (1.1.1998 — 31.12.2019), 298 out of 2960 males with F5_HABIT died.

Mortality risk

Mortality risk for people of age

years, who have F5_HABIT.

N-year risk Females Males
1 0.147% 0.549%
5 1.025% 3.198%
10 2.895% 8.048%
15 5.603% 15.009%
20 10.108% 24.073%

Relationships between endpoints

Index endpoint: F5_HABIT – Habit and impulse disorders

GWS hits: 1

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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