Other specified/unspecified deforming dorsopathies

M13_DEFORMDORSONAS

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

519972

1. Apply sex-specific rule

None

519972

2. Check conditions

None

519972

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 M43.8, M43.9
  • Hospital discharge: ICD-9 732[8-9]|737[8-9]
  • Hospital discharge: ICD-8 735
  • Cause of death: ICD-10 M43.8, M43.9
  • Cause of death: ICD-9 732[8-9]|737[8-9]
  • Cause of death: ICD-8 735

2 out of 7 registries used, show all original rules.

731

4. Check minimum number of events

None

731

5. Include endpoints

None

731

6. Filter based on genotype QC (FinnGen only)

707

Control definitions (FinnGen only)

Control exclude
M13_DORSOPATHY

Extra metadata

Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF2

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 6805 4430 2315
Only index persons 5608 3751 1857
Unadjusted period prevalence (%)
Whole population 0.11 0.13 0.06
Only index persons 0.12 0.14 0.07
Median age at first event (years)
Whole population 27.44 27.05 27.44
Only index persons 20.06 19.14 21.92

-FinnGen-

Key figures

All Female Male
Number of individuals 707 513 194
Unadjusted period prevalence (%) 0.16 0.18 0.09
Median age at first event (years) 21.30 17.16 32.25

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
731
Matched controls
7310
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
73599
ICD-8 Finland
Other and unspecified curvature of spine
+∞
307.7
339
*
9102
FHL
Trepanation or removal of the local bone process
82.2
162.9
87
12
M48.0
ICD-10 Finland
Spinal stenosis
32.6
127.9
84
29
M51.1
ICD-10 Finland
Lumbar and other intervertebral disc disorders with radiculopathy
18.8
125.8
104
64
M41.9
ICD-10 Finland
Scoliosis, unspecified
68.8
114.8
63
10
M43.9
ICD-10 Finland
Deforming dorsopathy, unspecified
+∞
99.3
93
*
NA3BG
NOMESCO Finland
Lumbar spine MRI examination with high intensity magnet
17.1
98.0
84
55
M43.1
ICD-10 Finland
Spondylolisthesis
31.6
92.5
61
21
7328A
ICD-9 Finland
Osteochondropathies, Other specified forms of osteochondropathy[JALKATERÄN YLIMÄÄRÄISTEN LUIDEN AIHEUTTAMAT OIREET]
+∞
85.1
80
*
7328B
ICD-9 Finland
Osteochondropathies, Other specified forms of osteochondropathy[MUIDEN YLIMÄÄRÄISTEN LUIDEN AIHEUTTAMAT OIREET]
+∞
84.0
79
*
M51.3
ICD-10 Finland
Other specified intervertebral disc degeneration
14.2
68.2
64
49
N03AX12
ATC
[U] gabapentin; oral
5.3
66.0
153
345
M47.2
ICD-10 Finland
Other spondylosis with radiculopathy
89.9
52.7
58
7
N03AX16
ATC
[U] pregabalin
3.9
49.9
185
591
7373A
ICD-9 Finland
Curvature of spine, Kyphoscoliosis and scoliosis
+∞
44.2
42
*
NA1BG
NOMESCO Finland
Cervical spine MRI examination with high intensity magnet
10.0
41.1
48
51
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
4.6
40.8
107
263
M54.4
ICD-10 Finland
Lumbago with sciatica
4.2
40.7
123
337
M54.5
ICD-10 Finland
Low back pain
3.0
40.6
259
1138
M41.1
ICD-10 Finland
Juvenile idiopathic scoliosis
+∞
40.0
38
*
M41.2
ICD-10 Finland
Other idiopathic scoliosis
211.2
39.2
40
*
ABC36
NOMESCO Finland
Decompression of lumbar nerve roots
108.5
38.1
41
*
9103
FHL
Partial or complete bone removal
108.5
38.1
41
*
M43.8
ICD-10 Finland
Other specified deforming dorsopathies
375.0
36.3
36
*
N02AX02
ATC
tramadol; systemic, rectal
2.7
36.0
316
1620
7378X
ICD-9 Finland
Curvature of spine, Other curvatures of spine
+∞
34.7
33
*
M54.9
ICD-10 Finland
Dorsalgia, unspecified
4.5
33.5
89
220
N06AX21
ATC
duloxetine; oral
3.8
33.3
116
349
NA7EA
NOMESCO Finland
Scoliosis X-ray examination
178.0
33.0
34
*
M43.0
ICD-10 Finland
Spondylolysis
115.1
30.9
33
*
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
6.0
30.5
56
100
M47.9
ICD-10 Finland
Spondylosis, unspecified
68.9
29.1
33
5
NA3CG
NOMESCO Finland
Lumbar spine extensive MRI examination with high intensity magnet
32.4
28.4
37
12
72870
ICD-8 Finland
Vertebrogenic pain syndrome, Lumbalgia
+∞
27.3
26
*
L03
ICPC
Low back symptom/complaint
2.6
27.1
196
893
7328X
ICD-9 Finland
Osteochondropathies, Other specified forms of osteochondropathy[OSTEOCHONDROPATHIAE ALIA DEFINITA]
+∞
25.1
24
*
M54.6
ICD-10 Finland
Pain in thoracic spine
4.3
22.6
62
156
NA3EA
NOMESCO Finland
Lumbar spine X-ray examination with flexion
82.7
21.8
24
*
N02AC04
ATC
dextropropoxyphene; oral
6.9
21.0
33
50
SPAT1229
SPAT
Assessment of need for aid
3.9
20.9
64
175
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
2.1
20.4
273
1594
N02BF01
ATC
gabapentin; oral
4.0
20.1
60
161
71798
ICD-8 Finland
Other nonarticular rheumatism, Other muscular rheumatism, fibrositis and myalgia
75.6
19.8
22
*
M54.3
ICD-10 Finland
Sciatica
5.7
19.5
37
68
M47.82
ICD-10 Finland
Other spondylosis, cervical region
17.3
19.3
30
18
M50.1
ICD-10 Finland
Cervical disc disorder with radiculopathy
14.7
18.7
31
22
7231A
ICD-9 Finland
Other disorders of cervical region, Cervicalgia
+∞
17.8
17
*
ABC16
NOMESCO Finland
Microsurgical excision of lumbar intervertebral disc displacement
+∞
17.8
17
*
NAG62
NOMESCO Finland
Posterior fusion of lumbar spine with fixation, 2-3 vertebraea
184.3
17.6
18
*
Z50.9
ICD-10 Finland
Care involving use of rehabilitation procedure, unspecified
4.7
17.5
41
91
M01AB55
ATC
diclofenac, combinations; oral
3.8
17.5
55
153
M41
ICD-10 Finland
Scoliosis
43.1
17.4
21
5
L28
ICPC
Limited function/disability (L)
2.5
17.2
120
528
NA1AA
NOMESCO Finland
Cervical spine X-ray examination without contrast
7.4
17.0
25
35
72898
ICD-8 Finland
Vertebrogenic pain syndrome, Alia definita
+∞
16.7
16
*
7329X
ICD-9 Finland
Osteochondropathies, Unspecified osteochondropathy
+∞
16.7
16
*
M79.6
ICD-10 Finland
Pain in limb
2.0
16.7
293
1859
L86
ICPC
Back syndrome with radiating pain
4.4
16.4
42
100
M50.3
ICD-10 Finland
Other cervical disc degeneration
21.5
16.1
23
11
R07.3
ICD-10 Finland
Other chest pain
2.9
16.0
81
303
M53.1
ICD-10 Finland
Cervicobrachial syndrome
2.8
15.9
83
315
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
2.5
15.8
112
496
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
2.1
15.7
187
1030
M03BX01
ATC
baclofen; systemic
6.6
15.5
25
39
NA2BG
NOMESCO Finland
Thoracal spine MRI examination with high intensity magnet
16.5
15.3
24
15
N06AA09
ATC
amitriptyline; systemic
3.1
15.0
66
228
72880
ICD-8 Finland
Vertebrogenic pain syndrome, Radicula syndrome of lower limbs
+∞
14.6
14
*
M41.8
ICD-10 Finland
Other forms of scoliosis
36.8
14.5
18
5
M54.8
ICD-10 Finland
Other dorsalgia
5.3
14.2
29
57
M01AH02
ATC
rofecoxib; oral
2.6
14.2
87
359
NA2AA
NOMESCO Finland
Thoracal spine X-ray examination without contrast
6.2
13.9
24
40
R52.2
ICD-10 Finland
Other chronic pain
4.6
13.9
33
74
J01MA02
ATC
ciprofloxacin; systemic
1.9
13.9
264
1696
M03BX02
ATC
tizanidine; oral
1.8
13.6
448
3394
N05BA04
ATC
oxazepam; oral
2.0
13.6
194
1132
7227C
ICD-9 Finland
Intervertebral disk disorders, Intervertebral disk disorder with myelopathy[SYNDROMA ISCHIADICUM]
+∞
13.6
13
*
NAG40
NOMESCO Finland
Anterior fusion of cervical spine without fixation
+∞
13.6
13
*
72510
ICD-8 Finland
Displacement of intervertebral disk, Lumbalis cum prolapsu disci
+∞
13.6
13
*
M54.1
ICD-10 Finland
Radiculopathy
10.3
13.6
26
26
M19.0
ICD-10 Finland
Primary arthrosis of other joints
2.7
13.2
75
298
G55.1*M51.1
ICD-10 Finland
Compression of nerve roots and nerve plexus in disc diseases in the lumbar region and other regions
19.5
13.0
19
10
F45.4
ICD-10 Finland
Persistent somatoform pain disorder
11.8
12.9
23
20
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.8
12.8
290
1954
R06.0
ICD-10 Finland
Dyspnoea
2.0
12.8
178
1027
H05BA01
ATC
calcitonin (salmon synthetic); nasal, parenteral
4.8
12.7
29
63
7245A
ICD-9 Finland
Other and unspecified disorders of back, Backache, unspecified
+∞
12.5
12
*
9359
FHL
Other measure in this category
+∞
12.5
12
*
73500, ,
ICD-8 Finland
+∞
12.5
12
*
72800
ICD-8 Finland
Vertebrogenic pain syndrome, Cervicalgia
+∞
12.5
12
*
1220
FHL
Arthroscopy
3.8
12.5
38
103
A02BC05
ATC
esomeprazole; systemic
1.8
12.5
285
1923
N02AA05
ATC
oxycodone; systemic
2.3
12.2
106
511
NA3AD
NOMESCO Finland
Lumbar spine and sacrum CT examination
11.3
12.1
22
20
N06AX16
ATC
venlafaxine; oral
2.2
12.1
112
555
M51.8
ICD-10 Finland
Other specified intervertebral disc disorders
47.5
11.9
14
*
A02BC02
ATC
pantoprazole; systemic
1.8
11.7
464
3635
A02BC01
ATC
omeprazole; systemic
1.9
11.6
180
1073
M01AE03
ATC
ketoprofen; systemic, rectal
1.8
11.6
249
1641
NAG63
NOMESCO Finland
Posterior fusion of lumbar spine with fixation, more than 3 vertebraea
+∞
11.5
11
*
M41.5
ICD-10 Finland
Other secondary scoliosis
+∞
11.5
11
*
M41.3
ICD-10 Finland
Thoracogenic scoliosis
121.9
11.5
12
*
ABC56
NOMESCO Finland
Decompression of lumbar spinal canal and nerve roots
121.9
11.5
12
*
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
2.9
11.3
54
195
Z01.8
ICD-10 Finland
Other specified special examinations
2.0
11.3
152
864
H02AB06
ATC
prednisolone; systemic
1.7
11.3
319
2270
N06AX11
ATC
mirtazapine; oral
1.8
11.3
236
1543
N05CF01
ATC
zopiclone; oral
1.8
11.2
227
1471
N02AJ06
ATC
codeine and paracetamol; systemic
1.7
11.0
271
1852
M79.0
ICD-10 Finland
Rheumatism, unspecified
4.9
11.0
24
50
N06CA01
ATC
amitriptyline and psycholeptics; systemic
2.5
11.0
72
306
M03BC51
ATC
orphenadrine, combinations; systemic
1.8
11.0
190
1172
R07.4
ICD-10 Finland
Chest pain, unspecified
1.9
10.9
172
1029
A02BC03
ATC
lansoprazole; oral
1.8
10.9
191
1182
M75.1
ICD-10 Finland
Rotator cuff syndrome
1.9
10.8
162
954
M54.2
ICD-10 Finland
Cervicalgia
3.1
10.6
46
157
M01AH05
ATC
etoricoxib; oral
1.7
10.5
430
3354
7151F
ICD-9 Finland
Osteo-arthrosis and allied disorders, Osteo-arthrosis, localised, primary[OSTEOARTHROSIS PRIMARIA, POLVI]
5.5
10.4
20
37
9193
FHL
Spondylodesis (also includes correction)
+∞
10.4
10
*
71310
ICD-8 Finland
Osteo-arthritis and allied conditions, Spondylarthritis cervicalis
+∞
10.4
10
*
ABC26
NOMESCO Finland
Open discectomy of lumbar spine
+∞
10.4
10
*
L02
ICPC
Back symptom/complaint
2.5
10.4
70
301
R52.1
ICD-10 Finland
Chronic intractable pain
33.0
10.4
13
*
ZZH21
NOMESCO Finland
Graft of patients own bone, small pieces
10.8
10.3
19
18
N02BF02
ATC
pregabalin; oral
3.2
10.3
40
128
L29
ICPC
Musculoskeletal sympt/complt other
2.6
10.1
61
249
M01AE51
ATC
ibuprofen, combinations; systemic
11.5
10.1
18
16
M47.80
ICD-10 Finland
Other spondylosis, multiple sites in spine
10.2
10.1
19
19
M03BA52
ATC
carisoprodol, combinations excl. psycholeptics; oral
3.9
10.0
29
76
N03AX09
ATC
lamotrigine; oral
3.1
10.0
41
136
M01AX17
ATC
nimesulide; oral
1.9
9.8
152
901
X59
ICD-10 Finland
Exposure to unspecified factor
1.9
9.7
127
712
R1250
NOMESCO Finland
Evaluation of functional capability
4.9
9.6
21
44
M70.6
ICD-10 Finland
Trochanteric bursitis
2.2
9.5
84
407
P03
ICPC
Feeling depressed
2.4
9.5
70
314
M96.1
ICD-10 Finland
Postlaminectomy syndrome, not elsewhere classified
101.3
9.4
10
*
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.8
9.4
180
1138
NAG65
NOMESCO Finland
Anterior and posterior fusion of lumbar spine
+∞
9.4
9
*
72850
ICD-8 Finland
Vertebrogenic pain syndrome, Pain in thoracic spine
+∞
9.4
9
*
71312
ICD-8 Finland
Osteo-arthritis and allied conditions, Spondylarthritis lumbalis sive lumbosacralis
+∞
9.4
9
*
R51.80
ICD-10 Finland
Headache
2.0
9.3
108
580
M01AH01
ATC
celecoxib; oral
2.0
9.3
109
588
N06AB04
ATC
citalopram; systemic
1.8
9.3
150
900
UJF32
NOMESCO Finland
Coloscopy
1.8
9.2
157
958
M79.7
ICD-10 Finland
Fibromyalgia
3.9
9.1
27
72
SPAT1301
SPAT
No procedures
1.7
9.1
184
1180
G55.2*M47.9
ICD-10 Finland
Nerve root and plexus compressions in spondylosis
15.8
9.1
14
9
N03AE01
ATC
clonazepam; systemic
2.9
9.0
42
150
NA1EA
NOMESCO Finland
Cervical spine X-ray examination with flexion
18.9
9.0
13
7
NF1AA
NOMESCO Finland
Hip X-ray examination
2.7
8.9
50
197
M25.5
ICD-10 Finland
Pain in joint
1.7
8.8
218
1475
SPAT1260
SPAT
Consultation of another employee
2.0
8.8
111
614
ZZH31
NOMESCO Finland
Bone allograft, small pieces
14.2
8.7
14
10
SPAT1240
SPAT
Therapeutic discussion
2.2
8.5
76
370
N02BE01
ATC
paracetamol; systemic, rectal
1.9
8.5
618
5453
AA1AD
NOMESCO Finland
CT of head and brain
1.8
8.4
157
981
K21.0
ICD-10 Finland
Gastro-oesophageal reflux disease with oesophagitis
2.3
8.4
66
304
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
2.5
8.4
53
221
NAU20
NOMESCO Finland
Removal of internal fixation device from spine or neck
91.1
8.4
9
*
L17
ICPC
Foot/toe symptom/complaint
1.7
8.4
182
1187
SPAT1263
SPAT
Sampling
1.6
8.4
265
1906
AB5BT
NOMESCO Finland
Blockage of nerv root with X-ray guidance
+∞
8.3
8
*
NAG53
NOMESCO Finland
Posterior or lateral fusion of thoracic spine with fixation, more than 3 vertebraea
+∞
8.3
8
*
J01DA01
ATC
[U] cefalexin
1.6
8.3
436
3524
A02BA02
ATC
ranitidine; systemic
1.8
8.3
126
741
M01AB05
ATC
diclofenac; systemic, rectal
1.6
8.3
449
3658
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
2.0
8.2
96
517
NJ2MA
NOMESCO Finland
Measurement of mechanical axis of lower leg with X-ray
2.7
8.0
43
166
Y88.3
ICD-10 Finland
Sequelae of surgical and medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
3.8
8.0
24
65
M03BC01
ATC
orphenadrine (citrate); systemic
1.8
7.9
138
846
NHG80
NOMESCO Finland
Fusion of first tarsometatarsal joint
3.4
7.9
28
85
F32.10
ICD-10 Finland
Moderate depressive episode without somatic syndrome
2.3
7.8
58
262
R03AC02
ATC
salbutamol; inhalant
1.5
7.7
379
2997
NA1AD
NOMESCO Finland
Cervical spine CT examination
3.1
7.7
31
102
J01FA01
ATC
erythromycin; systemic
1.9
7.7
97
537
R03BA01
ATC
beclometasone; inhalant
1.9
7.6
94
515
A02BA04
ATC
nizatidine; systemic
2.4
7.6
51
219
L01
ICPC
Neck symptom/complaint
1.9
7.6
98
545
75618
ICD-8 Finland
Other congenital anomalies of musculoskeletal system, Maleformationes columnae vertebralis aliae
25.3
7.6
10
*
Z46.8
ICD-10 Finland
Fitting and adjustment of other specified devices
4.2
7.6
20
49
R05DA20
ATC
opium alkaloids and derivatives - combinations
1.7
7.6
166
1084
M02AA07
ATC
piroxicam; topical
1.6
7.5
225
1589
SPAT1220
SPAT
Assessment of need for rehabilitation and/or rehabilitation plan
2.7
7.4
39
149
R52.9
ICD-10 Finland
Pain, unspecified
2.2
7.4
60
281
9211
FHL
Exploration or removal of diskusprolapse
+∞
7.3
7
*
NAG66
NOMESCO Finland
Posterior interbody fusion of lumbar spine, 2 vertebrae
+∞
7.3
7
*
NH3AA
NOMESCO Finland
Foot and toes X-ray examination
2.3
7.2
57
264
N05AH04
ATC
quetiapine; oral
1.8
7.2
117
701
S18
ICPC
Laceration/cut
1.5
7.1
267
1981
P01
ICPC
Feeling anxious/nervous/tense
2.0
7.1
76
397
A06AC01
ATC
ispaghula (psylla seeds); oral
1.7
7.0
161
1061
J01FA06
ATC
roxithromycin; oral
1.5
7.0
270
2013
G54.0
ICD-10 Finland
Brachial plexus disorders
4.4
7.0
17
39
H02BX01
ATC
methylprednisolone, combinations; systemic
3.0
7.0
31
108
TNX33
NOMESCO Finland
Custom moulded cast, unspecified region
2.6
7.0
39
154
NG1AA
NOMESCO Finland
Knee X-ray examination without contrast
2.1
6.9
69
351
A01
ICPC
Pain general/multiple sites
2.3
6.8
54
250
J01EA01
ATC
trimethoprim; systemic
1.6
6.8
182
1245
W00
ICD-10 Finland
Fall on same level involving ice and snow
2.0
6.8
75
395
M01AC06
ATC
meloxicam; systemic, rectal
1.6
6.8
229
1655
NA1BA
NOMESCO Finland
Cervical spine extensive X-ray examination without contrast
40.4
6.8
8
*
SPAT1148
SPAT
Treatment of chronic ulcer or burn
2.0
6.7
76
404
F32.9
ICD-10 Finland
Depressive episode, unspecified
1.9
6.7
85
470
SPAT1295
SPAT
Other function in accordance with physical therapy nomenclature
2.8
6.7
32
116
M51.9
ICD-10 Finland
Intervertebral disc disorder, unspecified
22.7
6.7
9
*
NH1AA
NOMESCO Finland
Ankle X-ray examination without contrast
2.3
6.6
47
208
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
1.7
6.6
148
969
C08CA02
ATC
felodipine; oral
2.2
6.5
52
242
B01AB05
ATC
enoxaparin; parenteral
1.6
6.5
193
1353
UKC02
NOMESCO Finland
Cystoscopy
1.9
6.4
79
433
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
2.2
6.4
51
237
202
Kela drug reimbursment
Connective tissue diseases, rheumatoid arthritis and comparable disease
2.0
6.4
67
347
L99
ICPC
Musculoskeletal disease other
4.1
6.4
17
42
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
1.6
6.4
178
1230
Y83
ICD-10 Finland
Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
2.3
6.3
45
199
SPAT1210
SPAT
Application of cast or individual aid
2.9
6.3
29
103
NA7DG
NOMESCO Finland
Spine and spinal cord very extensive MRI examination with high intensity magnet
9.4
6.3
12
13
M34.9
ICD-10 Finland
Systemic sclerosis, unspecified
18.2
6.3
9
5
M54
ICD-10 Finland
Dorsalgia
1.9
6.3
74
400
72820
ICD-8 Finland
Vertebrogenic pain syndrome, Diffuse syndrome cerviocobrachial
+∞
6.3
6
*
9191
FHL
Correction equipment installation
+∞
6.3
6
*
G99.2*M47.9
ICD-10 Finland
Myelopathy in spondylosis
+∞
6.3
6
*
7233A
ICD-9 Finland
Other disorders of cervical region, Cervicobrachial syndrome (diffuse)
+∞
6.3
6
*
M47.8
ICD-10 Finland
Other spondylosis
+∞
6.3
6
*
M41.4
ICD-10 Finland
Neuromuscular scoliosis
+∞
6.3
6
*
7210A
ICD-9 Finland
Spondylosis and allied disorders, Cervical spondylosis without myelopathy
+∞
6.3
6
*
72899
ICD-8 Finland
Vertebrogenic pain syndrome, Other and unspecified
+∞
6.3
6
*
M17.1
ICD-10 Finland
Other primary gonarthrosis
1.7
6.3
121
761
G55.1
ICD-10 Finland
Nerve root and plexus compressions in intervertebral disc disorders
26.9
6.2
8
*
UDQ12
NOMESCO Finland
Flexible laryngoscopy
2.5
6.2
37
151
K59.09
ICD-10 Finland
Constipation, unspecified
2.6
6.2
36
145
R4110, ,
SPAT
2.1
6.2
55
268
R5599
NOMESCO Finland
Other rehabilitation service
3.8
6.1
18
48
N39.0
ICD-10 Finland
Urinary tract infection, site not specified
1.8
6.1
92
538
ND1AA
NOMESCO Finland
Wrist X-ray examination
2.3
6.1
47
216
SPAT1325
SPAT
Vaccination
1.6
6.1
192
1363
J01AA02
ATC
doxycycline; systemic
1.5
6.1
534
4668
M81.9
ICD-10 Finland
Osteoporosis, unspecified
2.9
6.1
28
100

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
323
2183
1.86
14.66
14.1
11.9
1.22
1.22
inr
0.05
101
699
316
2169
1.80
13.26
6.4
5.4
1.21
1.22
mmol/l
1.15
287
1976
241
1558
1.82
12.10
2.6
2.2
57.58
62.76
u/l
0.44
227
1458
129
677
2.10
12.01
2.5
1.8
—
—
—
0
0
221
1407
1.82
11.59
4.0
3.7
7.40
7.40
ph
0.02
41
287
225
1443
1.81
11.50
2.8
2.0
179.54
240.40
u/l
0.45
213
1347
335
2457
1.67
10.31
7.4
6.2
1.21
1.22
mmol/l
1.36
281
2067
364
2728
1.67
10.30
6.6
6.1
10.52
11.11
umol/l
0.44
351
2584
194
1244
1.76
9.68
3.3
3.1
859.91
1249.15
ng/l
1.01
156
1042
508
4192
1.69
9.57
8.7
6.9
75.92
76.52
u/l
0.16
489
3950
149
894
1.84
9.24
1.4
1.2
20.40
11.55
u/ml
0.59
61
353
451
3656
1.61
8.67
5.5
3.7
—
—
—
0
0
427
3425
1.59
8.51
5.7
3.7
12.80
2919.73
e6/l
—
5
59
490
4063
1.62
8.48
5.3
3.5
10.56
11.48
mm/h
0.88
456
3768
182
1203
1.68
7.95
4.7
4.1
—
—
—
0
0
152
959
1.74
7.86
1.4
1.2
38.97
31.46
iu/ml
0.30
60
321
306
2310
1.56
7.68
2.5
2.1
76.65
76.08
nmol/l
0.13
269
2115
366
2912
1.51
7.00
5.8
4.1
6.57
6.66
mmol/l
0.38
346
2726
137
866
1.72
6.98
3.9
3.1
274.24
418.43
ng/l
0.42
97
597
285
2155
1.53
6.91
5.3
4.3
35.83
36.01
g/l
0.20
258
2009
53
243
2.27
6.87
4.7
5.5
—
—
—
0
0
186
1280
1.61
6.81
3.3
2.6
0.29
0.44
e6/l
0.76
142
943
183
1256
1.61
6.77
3.3
2.6
—
—
—
0
0
180
1233
1.61
6.71
1.4
1.2
3.94
1.52
u/ml
0.63
49
320
207
1469
1.57
6.63
3.7
2.7
—
—
—
0
0
323
2544
1.48
6.26
8.5
6.0
—
—
—
0
0
146
977
1.62
5.93
2.9
2.3
5.56
7.46
e6/l
0.80
129
883
276
2129
1.48
5.84
4.2
2.9
5.94
5.92
ph
0.05
26
210
103
633
1.73
5.77
2.8
2.2
24.01
22.97
%
0.32
84
543
245
1849
1.49
5.77
3.8
3.1
20.08
61.86
ng/l
1.25
165
1141
91
541
1.78
5.72
1.7
1.5
—
—
—
0
0
162
1124
1.57
5.63
1.6
1.7
446.51
27766382.30
pmol/l
1.28
136
940
341
2761
1.44
5.50
7.8
5.6
1.91
1.93
e9/l
0.08
307
2476
236
1782
1.48
5.49
3.7
3.3
2.34
2.35
mmol/l
0.75
209
1607
109
690
1.68
5.48
2.7
2.2
2.41
2.36
g/l
0.41
101
639
326
2620
1.44
5.47
4.8
3.1
0.00
0.00
estimate
-0.00
65
505
304
2412
1.45
5.46
2.7
2.3
—
—
—
0
0
157
1090
1.56
5.42
4.5
3.0
—
—
—
0
0
142
967
1.58
5.33
3.1
2.5
517.90
540.38
mosm/kgh2o
0.54
121
840
229
1730
1.47
5.28
4.4
3.1
75.60
120.15
e6/l
0.62
165
1166
328
2654
1.43
5.23
4.7
3.1
0.00
0.01
estimate
0.80
61
461
155
1082
1.55
5.21
1.5
1.5
2.15
2.29
g/l
0.45
95
697
184
1336
1.50
5.15
3.0
2.4
2774.47
4840.42
umol/l
0.36
159
1201
331
2691
1.42
5.10
7.7
5.7
0.04
0.04
e9/l
0.34
298
2355
184
1341
1.50
5.04
5.6
3.3
0.00
0.01
estimate
0.69
62
470
330
2689
1.41
4.98
7.6
5.6
0.56
0.55
e9/l
0.18
296
2350
195
1444
1.48
4.93
3.5
2.7
39.61
105.64
e6/l
0.71
150
1084
33
143
2.37
4.91
1.2
1.3
246.76
300.00
ug/g
0.83
17
81
104
675
1.63
4.74
2.3
2.2
100.21
119.02
ug/g
0.28
87
544
625
5758
1.59
4.65
17.3
11.1
22.01
22.14
mg/l
0.03
511
4425
323
2645
1.40
4.64
6.4
4.4
0.02
0.00
estimate
0.41
61
481
114
764
1.58
4.55
1.6
1.3
529.09
543.95
titre
0.04
22
162
338
2796
1.39
4.54
8.0
5.9
0.18
0.18
e9/l
0.11
306
2475
637
5907
1.61
4.47
18.0
12.4
139.59
139.70
mmol/l
0.50
621
5741
12
23
5.29
4.47
2.1
1.6
—
—
—
0
0
372
3137
1.38
4.40
11.0
9.2
4.08
3.99
e9/l
0.29
336
2749
90
579
1.63
4.25
2.6
2.5
9.86
7.16
umol/l
0.42
72
493
91
589
1.62
4.20
1.8
1.6
—
—
—
0
0
105
705
1.57
4.16
1.2
1.2
—
—
—
0
0
316
2614
1.37
4.13
7.8
5.6
57.50
57.07
%
0.25
302
2462
319
2644
1.37
4.11
8.1
5.8
27.92
28.26
%
0.21
304
2488
73
449
1.70
4.09
2.2
2.0
64.87
37.57
u/l
0.39
63
389
111
759
1.55
4.06
2.8
2.2
14.01
13.34
umol/l
0.53
105
703
75
466
1.68
4.05
10.3
7.9
5.09
5.07
kpa
0.07
70
453
66
396
1.73
4.05
2.2
2.8
10.24
10.59
g/l
0.25
57
367
637
5937
1.57
4.02
18.3
12.5
3.93
3.95
mmol/l
0.65
621
5759
7
7
10.08
4.01
1.6
3.0
—
—
—
0
0
92
605
1.60
3.98
6.3
5.2
1.05
1.03
mmol/l
0.34
82
566
209
1625
1.40
3.95
2.4
2.1
—
—
—
0
0
309
2566
1.35
3.87
8.2
5.9
8.40
8.35
%
0.10
294
2406
192
1479
1.40
3.81
3.9
3.3
—
—
—
0
0
149
1098
1.45
3.78
1.5
1.4
20.65
21.37
nmol/l
0.23
127
929
306
2552
1.34
3.67
8.0
5.7
2.86
2.81
%
0.14
290
2390
148
1095
1.44
3.67
5.3
3.3
1.01
1.02
kg/l
0.55
23
154
33
163
2.07
3.65
4.1
4.0
—
—
—
0
0
231
1852
1.36
3.57
3.8
3.2
29.44
31.39
u/l
0.50
218
1773
58
350
1.71
3.51
10.8
7.9
—
—
—
0
0
296
2470
1.33
3.49
8.1
5.7
0.68
0.68
%
0.04
280
2295
73
471
1.61
3.43
10.4
7.8
1.73
1.27
mmol/l
0.64
62
381
586
5422
1.41
3.35
5.7
4.6
1.87
2.08
mu/l
0.46
538
5021
33
170
1.99
3.29
2.4
4.1
24.43
25.14
mmol/l
1.14
27
161
504
4560
1.34
3.28
4.8
4.0
14.66
14.54
pmol/l
0.54
465
4212
59
365
1.67
3.27
2.9
3.3
76.35
75.71
ng/l
0.03
51
317
31
157
2.02
3.24
1.2
1.1
—
—
—
0
0
156
1196
1.39
3.14
1.7
1.6
1.05
1.06
mg/l
0.02
111
892
241
1978
1.33
3.12
2.1
1.8
97.27
97.88
pmol/l
0.07
121
1038
75
499
1.56
3.11
3.1
4.3
14.43
7.98
ug/l
0.32
54
389
156
1201
1.38
3.06
2.1
2.1
—
—
—
0
0
34
184
1.89
2.97
2.2
1.9
1318.10
2320.92
u/l
0.33
11
66
41
236
1.78
2.95
2.1
2.3
—
—
—
0
0
17
70
2.46
2.89
1.7
1.3
—
—
—
0
0
109
801
1.42
2.80
4.9
3.3
0.84
0.82
mmol/l
0.55
103
764
56
358
1.61
2.77
4.0
3.1
—
—
—
0
0
62
407
1.57
2.75
3.6
2.8
3.07
1.71
mmol/l
2.18
55
327
37
213
1.78
2.68
17.0
11.3
—
—
—
0
0
12
43
2.82
2.65
1.4
1.5
—
—
—
0
0
117
881
1.39
2.61
3.3
2.7
2.44
2.45
mmol/l
0.13
106
783
28
149
1.91
2.59
2.5
2.5
—
—
—
0
0
27
142
1.94
2.59
1.6
1.2
1.83
13.54
u/ml
—
7
25
49
309
1.63
2.57
1.3
1.2
—
—
—
0
0
12
44
2.76
2.55
1.5
2.2
3.97
7.24
umol/l
—
7
28
187
1518
1.31
2.55
1.3
1.4
—
—
—
0
0
69
473
1.51
2.53
2.1
2.1
0.21
0.22
g/l
0.89
62
454
187
1520
1.31
2.53
3.0
3.2
7.18
7.59
mmol/l
0.61
158
1300
55
361
1.57
2.46
1.4
1.4
—
—
—
0
0
33
189
1.78
2.45
1.0
1.0
—
—
—
0
0
154
1223
1.33
2.45
2.6
2.0
2.96
3.04
mg/l
0.15
134
1040
85
616
1.43
2.37
1.7
1.3
—
—
—
0
0
18
84
2.17
2.36
1.9
1.6
—
—
—
0
0
42
267
1.61
2.17
2.2
3.8
7.37
7.41
ph
—
5
34
7
19
3.71
2.15
1.9
2.0
—
—
—
0
0
187
1553
1.27
2.12
4.5
2.9
—
—
—
0
0
544
5088
1.27
2.12
19.7
13.7
14.66
14.74
%
0.13
534
4996
158
1285
1.29
2.11
4.3
3.4
88.58
94.16
%
1.76
151
1254
99
754
1.36
2.08
1.6
1.6
—
—
—
0
0
68
486
1.44
2.06
2.4
2.8
1.60
1.78
%
0.94
60
435
6
15
4.02
2.04
1.0
1.0
—
—
—
0
0
59
412
1.47
2.02
3.7
3.4
1.22
1.23
mmol/l
0.62
50
352
17
84
2.05
1.97
1.2
1.9
0.52
0.97
g/l
1.12
11
60
12
51
2.38
1.96
1.2
1.4
—
—
—
0
0
425
3886
1.22
1.95
4.0
3.2
—
—
—
0
0
5
11
4.57
1.94
4.4
3.1
—
—
—
0
0
56
392
1.46
1.90
4.1
4.2
0.50
0.73
%
0.31
18
124
108
846
1.32
1.90
1.9
1.7
1217.01
1173.15
nmol/l
0.19
82
635
12
52
2.33
1.88
1.1
1.4
—
—
—
0
0
55
385
1.46
1.87
4.9
4.4
0.53
0.96
%
0.20
16
102
92
708
1.34
1.82
3.2
2.4
2.66
3.62
e6/l
0.46
46
366
5
12
4.19
1.82
1.4
1.2
49.44
44.65
g/l
—
5
6
55
388
1.45
1.81
1.6
1.5
—
—
—
0
0
644
6197
1.33
1.73
15.5
10.8
—
—
—
0
0
57
409
1.43
1.72
4.8
4.4
0.06
0.15
%
0.75
18
127
27
164
1.67
1.70
1.2
1.1
—
—
—
0
0
32
204
1.59
1.68
2.4
3.8
—
—
—
0
0
12
55
2.20
1.68
1.1
1.4
—
0.58
nmol/l
—
0
5
284
2523
1.21
1.67
3.2
2.6
97.97
105.00
ug/l
0.39
266
2354
63
463
1.39
1.67
2.1
1.8
348.91
379.03
nmol/l
0.41
54
432
13
62
2.12
1.66
14.3
5.8
10.93
10.59
mg/l
0.08
13
56
29
181
1.63
1.66
1.6
1.9
1.63
1.47
g/l
0.32
23
157
15
76
1.99
1.65
1.5
2.4
15.78
16.52
%
—
6
44
33
214
1.57
1.62
1.1
1.6
—
11.40
—
0
5
5
14
3.59
1.62
1.0
1.1
—
—
—
0
0
8
32
2.52
1.60
2.9
2.1
585.38
425.70
e6/l
—
8
27
277
2465
1.20
1.59
11.7
8.4
0.00
0.00
e9/l
1.10
233
2041
59
434
1.39
1.57
4.7
4.3
0.50
1.11
%
1.76
20
151
160
1353
1.23
1.53
9.1
6.5
—
—
—
0
0
5
15
3.35
1.52
1.0
1.0
—
—
—
0
0
27
170
1.61
1.51
3.9
3.5
0.09
0.18
g/l
2.65
11
73
593
5672
1.24
1.50
4.5
4.0
5.78
5.84
mmol/l
0.68
550
5216
50
363
1.41
1.45
2.2
2.2
36.59
7.61
ug/l
0.88
43
316
228
2569
0.84
1.45
2.7
2.6
—
—
—
0
0
12
59
2.05
1.44
1.7
2.4
—
—
—
0
0
7
29
2.43
1.39
1.3
1.5
—
—
—
0
0
16
89
1.82
1.38
2.2
2.2
—
—
—
0
0
60
455
1.35
1.35
1.2
1.2
124.83
140.90
iu/ml
0.14
20
202
49
360
1.39
1.34
1.3
1.3
74.18
215.77
u/ml
2.58
43
331
35
494
0.69
1.31
1.3
1.4
—
—
—
0
0
264
2375
1.17
1.29
2.0
2.0
—
—
—
0
0
15
84
1.80
1.28
1.5
1.3
101.40
100.78
u/ml
—
5
18
59
451
1.34
1.27
5.3
3.3
—
—
—
0
0
163
1408
1.20
1.27
3.0
3.3
858.09
462.76
mg/l
0.29
102
901
14
77
1.83
1.26
1.2
1.9
—
—
—
0
0
16
92
1.76
1.26
1.3
1.8
—
—
—
0
0
27
179
1.53
1.25
2.4
3.6
1342.32
1834.16
u/ml
0.11
19
156
436
4088
1.16
1.24
3.4
2.8
40.71
45.41
u/l
0.89
410
3856
5
19
2.64
1.22
1.2
1.7
—
—
—
0
0
21
132
1.61
1.21
2.5
3.0
—
—
—
0
0
6
26
2.32
1.19
1.5
1.3
118.50
174.73
mmol/24h
—
6
26
16
94
1.72
1.18
1.7
2.0
—
—
—
0
0
16
94
1.72
1.18
1.3
2.0
114.55
130.54
g/l
1.10
11
76
17
102
1.68
1.17
2.8
3.6
—
—
—
0
0
57
441
1.32
1.15
1.2
1.2
—
—
—
0
0
8
154
0.51
1.15
1.0
1.1
—
—
—
0
0
648
6300
1.25
1.14
12.1
9.0
25.23
25.64
u/l
0.28
632
6096
47
354
1.35
1.13
2.4
2.9
66.62
67.29
g/l
0.22
40
334
8
40
2.01
1.12
1.4
1.2
—
—
—
0
0
8
40
2.01
1.12
2.6
1.5
1.34
1.21
promille
—
8
32
10
51
1.97
1.11
1.1
1.4
—
—
nmol/l
—
0
0
16
97
1.66
1.07
1.6
1.4
—
—
—
0
0
13
74
1.77
1.07
2.6
3.1
—
—
—
0
0
17
105
1.63
1.07
4.0
3.4
7.41
7.42
ph
0.17
17
94
51
394
1.32
1.05
11.8
7.3
9.35
9.00
mmol/l
0.13
51
372
170
1499
1.17
1.05
3.7
3.8
4.35
7.49
mg/mmol
1.36
111
944
15
90
1.68
1.04
1.1
1.1
—
—
—
0
0
5
22
2.28
1.03
1.6
1.0
199.40
177.85
iu/ml
—
5
22
678
6639
1.29
1.02
24.0
16.7
261.61
257.19
e9/l
0.99
666
6465
50
388
1.31
1.01
2.3
2.7
3.86
4.31
e9/l
0.65
39
328
16
99
1.63
1.00
1.3
1.2
263.09
318.55
u/ml
0.50
11
54
7
35
2.01
1.00
1.0
1.2
—
—
—
0
0
678
6643
1.28
0.98
23.9
16.6
91.12
90.67
fl
1.85
671
6539
678
6643
1.28
0.98
24.0
16.7
6.73
6.64
e9/l
0.32
667
6450
124
1071
1.19
0.98
5.0
4.2
3.43
2.37
ug/l
0.39
107
965
678
6644
1.28
0.97
23.8
16.6
30.27
30.19
pg
0.59
671
6540
678
6644
1.28
0.97
23.9
16.7
4.45
4.51
e12/l
2.38
666
6457
7
36
1.95
0.97
1.0
1.1
—
—
—
0
0
678
6648
1.27
0.93
24.1
16.8
133.99
135.37
g/l
1.79
672
6544
39
297
1.33
0.91
2.2
2.4
—
—
—
0
0
25
177
1.43
0.89
2.0
2.1
—
—
—
0
0
19
127
1.51
0.89
1.3
1.4
27.39
30.54
u/l
0.17
14
108
8
42
1.91
0.88
1.6
2.1
43.91
37.63
%
—
8
42
44
345
1.29
0.85
2.0
3.0
69.07
70.96
e9/l
0.16
34
267
61
499
1.24
0.84
3.3
4.4
—
—
—
0
0
28
205
1.38
0.84
1.3
1.2
—
—
—
0
0
109
945
1.18
0.84
2.2
1.6
—
—
—
0
0
72
601
1.22
0.83
1.4
1.2
—
—
—
0
0
8
46
1.75
0.82
1.4
1.5
278.75
282.79
mosm/kgh2o
—
8
34
11
65
1.70
0.82
1.0
1.1
—
—
—
0
0
6
32
1.88
0.82
2.7
3.0
38033.33
40584.38
ug/l
—
6
32
6
32
1.88
0.82
1.2
1.0
—
—
—
0
0
11
66
1.68
0.79
1.0
1.1
—
—
—
0
0
26
193
1.36
0.74
1.9
1.8
—
—
—
0
0
14
92
1.53
0.72
1.4
1.7
—
—
—
0
0
14
92
1.53
0.72
1.1
1.5
—
—
—
0
0
26
194
1.35
0.72
1.9
2.0
—
—
—
0
0
164
1485
1.13
0.72
1.8
1.6
1.31
1.40
mmol/l
0.71
142
1261
9
57
1.59
0.71
1.8
1.3
18.21
44.03
mu/l
—
9
51
45
364
1.25
0.71
1.2
1.2
—
—
—
0
0
71
603
1.20
0.71
1.6
1.6
—
—
—
0
0
26
195
1.35
0.70
1.9
2.0
—
—
—
0
0
9
58
1.56
0.70
1.6
1.3
386.22
448.80
pmol/l
—
9
50
14
93
1.52
0.70
4.4
1.9
—
—
—
0
0
54
447
1.22
0.70
1.6
1.3
26.38
31.03
iu/l
0.47
48
388
22
161
1.38
0.69
2.3
3.4
—
—
—
0
0
26
196
1.34
0.68
1.9
2.0
—
—
—
0
0
674
6634
1.20
0.66
24.4
16.7
39.83
40.17
%
0.74
638
6273
5
28
1.79
0.66
1.2
1.0
—
—
—
0
0
6
101
0.59
0.62
1.5
1.2
—
—
—
0
0
39
316
1.25
0.62
3.0
2.9
—
—
—
0
0
5
30
1.67
0.61
1.6
1.5
—
—
—
0
0
13
88
1.49
0.61
1.3
3.0
7.81
8.13
kpa
0.26
13
88
0
21
0.00
0.60
0.0
2.7
—
33.94
—
0
16
8
52
1.54
0.59
1.1
1.1
—
—
—
0
0
8
53
1.51
0.58
1.4
1.2
—
—
—
0
0
39
473
0.81
0.58
1.6
1.7
—
—
—
0
0
21
158
1.34
0.57
7.2
6.9
—
—
—
0
0
6
36
1.67
0.56
2.2
2.9
—
—
—
0
0
11
73
1.51
0.56
1.4
2.8
—
—
—
0
0
8
55
1.46
0.56
2.8
2.5
—
—
—
0
0
547
5328
1.11
0.56
5.7
5.0
39.36
39.25
mmol/mol
0.10
509
4977
6
37
1.63
0.55
2.3
1.5
10.37
10.41
%
—
6
37
6
37
1.63
0.55
1.3
1.2
—
—
—
0
0
6
39
1.54
0.53
1.0
1.1
—
—
—
0
0
10
66
1.52
0.52
1.5
2.3
—
—
—
0
0
35
290
1.22
0.48
2.7
2.3
12.45
12.54
nmol/l
0.02
30
271
7
47
1.49
0.47
1.3
1.1
—
—
—
0
0
7
47
1.49
0.47
1.0
1.1
—
—
—
0
0
26
210
1.25
0.45
2.2
1.8
—
—
—
0
0
7
51
1.38
0.44
1.0
1.3
—
—
—
0
0
18
139
1.30
0.44
2.2
2.2
—
—
—
0
0
0
15
0.00
0.41
0.0
2.9
—
85.91
—
0
8
5
34
1.47
0.40
1.0
1.2
—
—
—
0
0
5
34
1.47
0.40
1.0
1.3
183.98
176.79
pmol/l
—
5
34
18
142
1.27
0.39
1.2
1.2
—
1190.00
—
0
7
5
37
1.35
0.37
1.0
1.2
—
—
—
0
0
81
737
1.11
0.37
1.3
1.2
—
—
—
0
0
28
235
1.20
0.36
3.6
3.5
—
—
—
0
0
12
90
1.34
0.36
4.1
3.6
—
—
—
0
0
6
43
1.40
0.35
1.2
3.6
—
—
—
0
0
6
45
1.34
0.34
4.5
3.2
47.00
54.29
%
—
6
40
6
47
1.28
0.32
1.5
2.0
—
—
—
0
0
7
53
1.32
0.31
5.6
3.6
—
—
—
0
0
7
53
1.32
0.31
1.4
1.5
—
—
—
0
0
12
93
1.30
0.30
1.2
1.7
—
—
—
0
0
23
194
1.19
0.30
1.2
1.4
172.40
247.30
miu/ml
—
5
102
19
157
1.22
0.29
1.3
1.2
—
—
—
0
0
7
56
1.25
0.29
1.1
3.4
—
—
—
0
0
70
643
1.10
0.28
3.2
2.6
0.62
0.81
ug/l
1.73
42
380
10
76
1.32
0.28
1.4
1.3
—
—
—
0
0
64
587
1.10
0.27
1.7
1.5
—
—
—
0
0
9
76
1.19
0.24
6.8
3.0
1.33
1.57
%
—
9
68
12
96
1.25
0.24
1.2
1.1
1.29
4.11
u/ml
—
7
36
5
38
1.32
0.23
2.0
1.2
2.04
2.02
mmol/l
—
5
38
7
94
0.74
0.22
1.4
1.1
—
—
—
0
0
5
42
1.19
0.21
9.6
7.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.4
—
14.40
—
0
5
0
10
0.00
0.21
0.0
1.2
—
—
—
0
0
0
10
0.00
0.21
0.0
1.4
—
—
—
0
0
0
10
0.00
0.21
0.0
4.6
—
—
—
0
0
5
43
1.16
0.21
1.6
1.4
—
—
—
0
0
48
441
1.09
0.21
1.7
1.5
—
—
—
0
0
0
13
0.00
0.21
0.0
2.2
—
—
—
0
0
0
14
0.00
0.20
0.0
1.1
—
—
—
0
0
0
14
0.00
0.20
0.0
1.2
—
12.38
—
0
9
11
90
1.23
0.19
3.8
2.9
3.54
4.32
e9/l
0.56
11
90
6
52
1.16
0.19
1.3
1.1
427.17
467.57
nmol/l
—
6
44
12
100
1.20
0.18
2.1
1.5
—
—
—
0
0
7
59
1.19
0.18
3.9
1.9
—
—
—
0
0
22
195
1.13
0.17
1.5
1.7
—
—
—
0
0
7
61
1.15
0.17
1.9
2.7
—
—
—
0
0
608
6029
1.05
0.17
4.7
4.3
2.80
2.88
mmol/l
1.17
562
5619
10
82
1.22
0.17
1.0
1.0
—
—
—
0
0
13
111
1.17
0.16
1.2
1.2
—
—
—
0
0
11
93
1.19
0.14
1.7
1.7
175.73
217.51
pmol/l
0.66
11
88
14
122
1.15
0.14
1.1
1.1
—
—
—
0
0
14
122
1.15
0.14
1.1
1.1
—
—
—
0
0
11
94
1.17
0.13
4.0
3.2
55.09
57.13
%
0.17
11
94
598
5941
1.04
0.12
4.4
4.0
4.73
4.82
mmol/l
1.54
558
5573
5
44
1.14
0.10
3.8
2.9
—
—
—
0
0
5
48
1.04
0.09
1.2
1.5
1.44
1.58
g/l
—
5
48
6
54
1.11
0.09
1.2
1.1
—
—
—
0
0
62
643
0.96
0.08
1.2
1.4
—
—
—
0
0
8
74
1.08
0.07
5.1
1.4
60.94
63.56
%
—
8
74
7
85
0.82
0.07
1.1
1.0
—
—
—
0
0
10
89
1.13
0.07
1.0
1.1
—
15.40
—
0
8
28
295
0.95
0.06
1.0
1.1
—
—
—
0
0
571
5733
0.98
0.06
3.9
3.6
1.28
1.28
mmol/l
0.00
530
5318
11
100
1.10
0.05
1.4
1.1
—
—
—
0
0
15
140
1.07
0.04
5.4
4.3
—
—
—
0
0
594
5922
1.02
0.04
4.3
3.9
1.49
1.51
mmol/l
0.68
553
5524
20
190
1.05
0.04
1.5
1.3
—
—
—
0
0
80
786
1.02
0.03
1.4
1.3
—
—
—
0
0
49
501
0.98
0.03
1.5
1.4
—
—
—
0
0
15
157
0.95
0.01
2.5
2.0
3.15
6.16
iu/l
—
6
60
10
96
1.04
0.00
3.2
1.7
—
—
—
0
0
13
128
1.02
0.00
2.3
2.2
29.61
118.11
ug/min
—
8
82
0
8
0.00
0.00
0.0
1.6
—
—
—
0
0
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
0.00
0.0
2.2
—
321.00
—
0
6
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.3
—
1.84
—
0
6
6
65
0.92
-0.00
1.0
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
15.98
—
0
5
0
5
0.00
-0.00
0.0
3.6
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
5
52
0.96
-0.00
1.2
1.7
1.03
1.04
g/l
—
5
52
0
5
0.00
-0.00
0.0
1.2
—
16.42
—
0
5
6
61
0.98
-0.00
1.2
2.6
32.17
32.48
pg
—
6
61
0
7
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
5.1
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.7
—
—
—
0
0
0
5
0.00
-0.00
0.0
2.2
—
—
—
0
0
5
53
0.94
-0.00
1.0
1.1
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.7
—
—
—
0
0
7
69
1.01
-0.00
1.1
1.1
—
—
—
0
0
12
120
1.00
-0.00
1.2
1.1
0.35
2.00
u/ml
—
7
54
0
5
0.00
-0.00
0.0
4.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
2.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint M13_DEFORMDORSONAS and mortality.

Females

Parameter HR [95% CI] p-value
M13_DEFORMDORSONAS 1.568 [1.23, 2.0] < 0.001
Birth year 0.997 [0.99, 1.01] 0.519

During the follow-up period (1.1.1998 — 31.12.2019), 118 out of 546 females with M13_DEFORMDORSONAS died.

Males

Parameter HR [95% CI] p-value
M13_DEFORMDORSONAS 1.136 [0.78, 1.64] 0.5
Birth year 0.984 [0.97, 0.99] < 0.001

During the follow-up period (1.1.1998 — 31.12.2019), 67 out of 373 males with M13_DEFORMDORSONAS died.

Mortality risk

Mortality risk for people of age

years, who have M13_DEFORMDORSONAS.

N-year risk Females Males
1 0.184% 0.208%
5 1.08% 1.234%
10 2.375% 3.06%
15 4.839% 5.699%
20 8.709% 9.628%

Relationships between endpoints

Index endpoint: M13_DEFORMDORSONAS – Other specified/unspecified deforming dorsopathies

GWS hits: 1

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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