No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleonly females |
293373 |
2. Check conditionsNone |
293373 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
598 |
4. Check minimum number of eventsNone |
598 |
5. Include endpointsNone |
598 |
6. Filter based on genotype QC (FinnGen only) |
598 |
Control definitions (FinnGen only)
- Control exclude
- N14_FEMALEGENNONINF
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- N80-N98
- Name in latin
- Fistulae organorum genitalium femininorum
Similar endpoints
↥List of similar endpoints to
Fistulae involving female genital tract
based on the number of shared cases.
Similar with more cases:
- Noninflammatory disorders of female genital tract
- Genitourinary diseases
- Any operation in hilmo
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 4095 | 4095 | - |
| Only index persons | 3636 | 3636 | - |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.12 | 0.12 | - |
| Only index persons | 0.13 | 0.13 | - |
| Median age at first event (years) | |||
| Whole population | - | 53.59 | - |
| Only index persons | - | 51.83 | - |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 598 | 598 | - |
| Unadjusted period prevalence (%) | 0.20 | 0.20 | - |
| Median age at first event (years) | 51.10 | 51.10 | - |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 550
- Matched controls
- 5500
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
N82.3
ICD-10 Finland
Fistula of vagina to large intestine
+∞
235.9
209
*
N82.0
ICD-10 Finland
Vesicovaginal fistula
+∞
124.9
115
*
N82.1
ICD-10 Finland
Other female urinary-genital tract fistulae
+∞
121.5
112
*
LC2BE
NOMESCO Finland
Transvaginal ultrasound examination of uterus, parametria and lower abdomen
8.4
104.8
294
661
N83.2
ICD-10 Finland
Other and unspecified ovarian cysts
43.2
91.9
114
33
N82.4
ICD-10 Finland
Other female intestinal-genital tract fistulae
+∞
69.2
65
*
UKC02
NOMESCO Finland
Cystoscopy
8.5
61.6
147
225
Z09.0
ICD-10 Finland
Follow-up examination after surgery for other conditions
11.2
55.9
111
121
UJF45
NOMESCO Finland
Flexible sigmoidoscopy with biopsy
8.5
55.5
131
194
LCA06
NOMESCO Finland
Biopsy of endometrium
11.1
55.1
110
121
N95.1
ICD-10 Finland
Menopausal and female climacteric states
+∞
53.0
50
*
N95.0
ICD-10 Finland
Postmenopausal bleeding
30.0
52.8
71
27
N84.0
ICD-10 Finland
Polyp of corpus uteri
80.6
52.2
58
8
N81.1
ICD-10 Finland
Cystocele
41.6
50.7
63
17
N81.2
ICD-10 Finland
Incomplete uterovaginal prolapse
74.6
48.1
54
8
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
6.8
46.1
127
232
LCA13
NOMESCO Finland
Curettage of cervix and body of uterus
38.0
45.8
58
17
N81.6
ICD-10 Finland
Rectocele
38.8
44.4
56
16
N92.0
ICD-10 Finland
Excessive and frequent menstruation with regular cycle
21.5
43.9
65
34
P01AB01
ATC
metronidazole; oral, rectal
3.4
41.1
326
1638
N82.2
ICD-10 Finland
Fistula of vagina to small intestine
+∞
40.1
38
*
LEF00
NOMESCO Finland
Anterior colporraphy with sutures for primary cystocele
147.3
39.3
41
*
LEF03
NOMESCO Finland
Posterior colporrpahy with sutures for primary rectocele
404.1
38.5
38
*
N80.3
ICD-10 Finland
Endometriosis of pelvic peritoneum
+∞
38.0
36
*
J01MA02
ATC
ciprofloxacin; systemic
3.3
37.3
274
1269
WX408
NOMESCO Finland
General anesthesy, balanced
3.6
37.3
217
841
LEE30
NOMESCO Finland
Closure of intestinovaginal fistula using graft or flap
+∞
36.9
35
*
XLD00
NOMESCO Finland
Sytologyspecimen from mouth of uterus
5.6
36.2
115
247
N92.4
ICD-10 Finland
Excessive bleeding in the premenopausal period
63.1
35.7
41
7
KBV02
NOMESCO Finland
Cystoscopic insertion of stent into ureter
22.0
35.6
52
26
N80.1
ICD-10 Finland
Endometriosis of ovary
+∞
34.8
33
*
UJF32
NOMESCO Finland
Coloscopy
3.6
34.7
201
767
JN3BD
NOMESCO Finland
Extensive abdominal CT
4.9
31.8
113
273
N95.2
ICD-10 Finland
Postmenopausal atrophic vaginitis
+∞
31.6
30
*
N92.6
ICD-10 Finland
Irregular menstruation, unspecified
19.6
31.1
47
26
LC2AE
NOMESCO Finland
Ultrasound examination of uterus and parametria
5.5
31.1
99
211
LX1AE
NOMESCO Finland
Gynecological ultrasound examination as part of clinical examination
5.8
30.8
94
190
ULC02
NOMESCO Finland
Hysteroscopy
18.9
30.7
47
27
LEE20
NOMESCO Finland
Closure of urovaginal fistula using graft or flap
+∞
30.5
29
*
T81.2
ICD-10 Finland
Accidental puncture and laceration during a procedure, not elsewhere classified
28.6
29.7
40
15
N92.1
ICD-10 Finland
Excessive and frequent menstruation with irregular cycle
22.1
29.6
43
21
N82.9
ICD-10 Finland
Female genital tract fistula, unspecified
+∞
28.4
27
*
LEF13
NOMESCO Finland
Colpoperineoplasty and vaginal hysterectomy
+∞
28.4
27
*
N02AX02
ATC
tramadol; systemic, rectal
2.8
27.8
266
1382
N82.8
ICD-10 Finland
Other female genital tract fistulae
+∞
27.3
26
*
D25.9
ICD-10 Finland
Leiomyoma of uterus, unspecified
5.1
26.5
90
205
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
3.2
25.6
159
616
JAH00
NOMESCO Finland
Laparotomy
11.8
25.4
47
43
LCD00
NOMESCO Finland
Hysterectomy
6.3
25.3
70
124
G03CA03
ATC
estradiol; nasal, systemic, rectal, transdermal, vaginal
2.6
25.2
356
2267
JN3AD
NOMESCO Finland
Abdominal CT examination
5.6
25.2
77
155
WX302
NOMESCO Finland
Thoracal epidural anesthesy
5.9
25.1
73
138
LCB25
NOMESCO Finland
Hysteroscopic excision of lesion
73.4
25.0
28
*
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
2.7
25.0
235
1189
LCD04
NOMESCO Finland
Laparoscopic hysterectomy
10.8
24.8
48
48
Y83
ICD-10 Finland
Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
5.2
24.2
79
171
KBH20
NOMESCO Finland
Replantation of ureter
90.9
23.9
26
*
ZXE20
NOMESCO Finland
More than three and less than five hours
3.6
23.0
116
380
N80.9
ICD-10 Finland
Endometriosis, unspecified
239.5
22.8
23
*
N97.9
ICD-10 Finland
Female infertility, unspecified
125.2
22.8
24
*
JFF23
NOMESCO Finland
Transversostomy
20.6
22.4
33
17
N80.0
ICD-10 Finland
Endometriosis of uterus
+∞
22.0
21
*
JFF10
NOMESCO Finland
Loop enterostomy
45.3
21.6
26
6
LAF01
NOMESCO Finland
Laparoscopic unilateral salpingo-oophorectomy
24.3
21.5
30
13
A06AC01
ATC
ispaghula (psylla seeds); oral
2.7
21.5
176
804
K60.3
ICD-10 Finland
Anal fistula
20.5
21.1
31
16
6262A
ICD-9 Finland
Disorders of menstruation and other abnormal bleeding from female genital tract, Excessive or frequent menstruation[HYPERMENORRHOEA]
+∞
21.0
20
*
LCD10
NOMESCO Finland
Vaginal hysterectomy
12.3
20.6
37
32
LAF11
NOMESCO Finland
Laparoscopic bilateral salpingo-oophorectomy
7.6
20.3
48
68
8113
FHL
Fractional scraping
11.9
20.3
37
33
ULA02
NOMESCO Finland
Kolposcopy
4.4
20.0
77
198
C20.91
ICD-10 Finland
Malignant tumor of the rectum invasive carcinoma
9.9
19.4
39
42
N73.6
ICD-10 Finland
Female pelvic peritoneal adhesions
47.8
19.3
23
5
JN2CG
NOMESCO Finland
Extensive MRI examination of lower part of abdoment with high intensity magnet
15.6
19.1
31
21
ZXE10
NOMESCO Finland
More than one and less than three hours
2.4
19.0
234
1312
WX404
NOMESCO Finland
Intravenous generell anesthesy
2.7
18.9
157
713
JFG10
NOMESCO Finland
Closure of loop colostomy without resection
17.9
18.9
29
17
JN2DG
NOMESCO Finland
Very extensive MRI examination of lower part of abdoment with high intensity magnet
29.0
18.9
25
9
N02AA05
ATC
oxycodone; systemic
3.3
18.7
107
380
JFG00
NOMESCO Finland
Closure of loop enterostomy without resection
39.9
18.7
23
6
JGB00
NOMESCO Finland
Partial proctectomy and colorectal or coloanal anastomosis
39.9
18.7
23
6
JHD33
NOMESCO Finland
Completing incision of fistula-in-ano
103.6
18.7
20
*
XKD00
NOMESCO Finland
Uroflowmetry
6.8
18.5
47
74
J01MA12
ATC
levofloxacin; systemic
3.0
18.5
123
487
WZC00
NOMESCO Finland
Planning of intervention or health care consultation
2.4
18.4
214
1165
JN3CD
NOMESCO Finland
Abdominal CT examination both without and with contrast
8.5
18.3
40
50
UJH02
NOMESCO Finland
Anoscopy
6.4
18.3
49
83
LEB00
NOMESCO Finland
Biopsy of vagina
13.6
18.1
31
24
T81.8
ICD-10 Finland
Other complications of procedures, not elsewhere classified
10.9
17.9
34
33
Y83.9
ICD-10 Finland
Surgical procedure, unspecified as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
9.8
17.9
36
39
6266A
ICD-9 Finland
Disorders of menstruation and other abnormal bleeding from female genital tract, Metrorrhagia
+∞
17.8
17
*
N80.4
ICD-10 Finland
Endometriosis of rectovaginal septum and vagina
+∞
17.8
17
*
LAF10
NOMESCO Finland
Bilateral salpingo-oophorectomy
6.6
17.7
46
75
LEB10
NOMESCO Finland
Excision of lesion of vagina
98.3
17.7
19
*
K50.8
ICD-10 Finland
Other Crohn disease
13.7
17.6
30
23
J01DB01
ATC
cefalexin; oral
2.6
17.5
460
3646
H01CA02
ATC
nafarelin; nasal
21.7
17.4
25
12
B01AB05
ATC
enoxaparin; parenteral
2.4
17.3
196
1044
LCD01
NOMESCO Finland
Total laparoscopic hysterectomy
15.5
17.3
28
19
A02BC02
ATC
pantoprazole; systemic
2.2
17.2
376
2707
KBV12
NOMESCO Finland
Transluminal endoscopic removal of stent from ureter
16.6
17.2
27
17
TLW99
NOMESCO Finland
Other minor surgical procedure in gynaecology
20.1
17.0
25
13
KCH00
NOMESCO Finland
Suture of bladder
65.4
16.8
19
*
TKC20
NOMESCO Finland
Catheterisation of bladder
5.2
16.8
53
110
62660
ICD-8 Finland
Disorders of menstruation, Intermenstrual bleeding
+∞
16.7
16
*
LAA10
NOMESCO Finland
Percutaneous or transvaginal puncture and recovery of oocyte
+∞
16.7
16
*
JAP01
NOMESCO Finland
Laparoscopic freeing of adhesions in the peritoneal cavity
20.8
16.6
24
12
N70.1
ICD-10 Finland
Chronic salpingitis and oophoritis
20.8
16.6
24
12
N02BE01
ATC
paracetamol; systemic, rectal
2.8
16.4
486
4017
J02AC01
ATC
fluconazole; systemic
2.1
16.2
290
1888
GD1AA
NOMESCO Finland
Thorax X-ray examination
2.2
16.2
242
1459
J01EA01
ATC
trimethoprim; systemic
2.3
15.9
194
1061
N82.5
ICD-10 Finland
Female genital tract-skin fistulae
+∞
15.7
15
*
N81.5
ICD-10 Finland
Vaginal enterocele
+∞
15.7
15
*
K43.9
ICD-10 Finland
Other and unspecified ventral hernia without obstruction or gangrene
5.7
15.6
45
84
LX1XE
NOMESCO Finland
Other gynecological ultrasound examination
8.1
15.6
35
46
208
Kela drug reimbursment
Ulcerative colitis and Crohn's disease
5.1
15.6
50
106
WX602
NOMESCO Finland
Repeated or continuing anesthesia shots throug a catheter
3.3
15.5
82
275
ZXE00
NOMESCO Finland
One hour or less
2.1
15.3
245
1513
XJH00
NOMESCO Finland
Transanal ultrasonography
24.2
15.2
21
9
K57.2
ICD-10 Finland
Diverticular disease of large intestine with perforation and abscess
9.3
15.1
31
35
B02AA02
ATC
tranexamic acid; systemic
2.9
15.1
100
388
KBV00
NOMESCO Finland
Insertion of stent into ureter
32.7
14.9
19
6
JFB46
NOMESCO Finland
Resection of sigmoid colon
19.0
14.8
22
12
N39.3
ICD-10 Finland
Stress incontinence
4.0
14.8
61
167
LEE00
NOMESCO Finland
Suture of vagina
+∞
14.6
14
*
N13.3
ICD-10 Finland
Other and unspecified hydronephrosis
10.5
14.6
28
28
N85.0
ICD-10 Finland
Endometrial glandular hyperplasia
153.9
14.5
15
*
KC1GB
NOMESCO Finland
Cystography with X-ray
153.9
14.5
15
*
N99.3
ICD-10 Finland
Prolapse of vaginal vault after hysterectomy
153.9
14.5
15
*
JH1CG
NOMESCO Finland
Extensive MRI of perianal area
37.1
14.5
18
5
WX402
NOMESCO Finland
General anaesthesia
2.7
14.5
110
468
T81.3
ICD-10 Finland
Disruption of operation wound, not elsewhere classified
7.7
14.4
33
45
K50.1
ICD-10 Finland
Crohn disease of large intestine
17.6
14.4
22
13
ZXD10
NOMESCO Finland
Scheduled procedure
2.1
14.3
234
1443
JAP00
NOMESCO Finland
Freeing of adhesions in the peritoneal cavity
14.9
14.2
23
16
R87.6
ICD-10 Finland
Abnormal findings in specimens from female genital organs, abnormal cytological findings
3.4
14.1
71
229
TJF80
NOMESCO Finland
Ostomy education
16.3
14.0
22
14
UJG02
NOMESCO Finland
Proctoscopy
8.5
14.0
30
37
LBE01
NOMESCO Finland
Laparoscopic salpingectomy
11.8
13.9
25
22
8140/3-C20.9
ICD-O-3
Adenocarcinoma, NOS, of rectum, NOS
8.9
13.9
29
34
J01CA08
ATC
pivmecillinam; oral
2.0
13.7
311
2171
K56.6
ICD-10 Finland
Other and unspecified intestinal obstruction
7.1
13.7
33
49
6190A
ICD-9 Finland
Fistulae involving female genital tract, Urinary-genital tract fistulae, female
+∞
13.6
13
*
62699
ICD-8 Finland
Disorders of menstruation, Other
+∞
13.6
13
*
KC1EE
NOMESCO Finland
Ultrasound measurement of residual urine
5.8
13.6
38
69
N97.8
ICD-10 Finland
Female infertility of other origin
143.4
13.5
14
*
JHD50
NOMESCO Finland
Excision of fistula-in-ano with advancement flap of mucosa
143.4
13.5
14
*
N39.0
ICD-10 Finland
Urinary tract infection, site not specified
2.8
13.4
95
386
D25.1
ICD-10 Finland
Intramural leiomyoma of uterus
4.2
13.3
51
130
K61.0
ICD-10 Finland
Anal abscess
14.3
13.3
22
16
N83.0
ICD-10 Finland
Follicular cyst of ovary
41.1
13.2
16
*
JHW96
NOMESCO Finland
Other operation on anus or perianal tissue
51.3
12.9
15
*
N03AX16
ATC
pregabalin; oral
2.2
12.8
147
771
QBB10
NOMESCO Finland
Major dressing of wound of skin of trunk
5.0
12.7
41
88
K57.3
ICD-10 Finland
Diverticular disease of large intestine without perforation or abscess
2.5
12.7
107
478
WX306
NOMESCO Finland
Lumbar epidural anesthesy
3.7
12.7
57
168
TPH07
NOMESCO Finland
Cathetrisation of artery
3.0
12.7
77
284
LC2DE
NOMESCO Finland
Demanding ultrsound examination of uterus, parametrium and lower part of abdomen with speciel methods
6.6
12.6
32
51
N83.1
ICD-10 Finland
Corpus luteum cyst
+∞
12.5
12
*
UJF14
NOMESCO Finland
Enteroscopy of ileoanal anastomosis
25.0
12.5
17
7
K50.9
ICD-10 Finland
Crohn disease, unspecified
13.6
12.5
21
16
H02AB06
ATC
prednisolone; systemic
1.9
12.5
269
1819
ZXD05
NOMESCO Finland
Urgent procedure
2.1
12.3
181
1051
C20.90
ICD-10 Finland
Malignant tumor of the rectum without histology
11.4
12.1
22
20
Y60
ICD-10 Finland
Unintentional cut, puncture, perforation or haemorrhage during surgical and medical care
21.9
12.1
17
8
G03GA05
ATC
follitropin alfa; parenteral
21.9
12.1
17
8
N30.0
ICD-10 Finland
Acute cystitis
2.5
12.1
101
450
KH1BT
NOMESCO Finland
Urinary tract cathetrisation with X-ray guidance
13.8
12.0
20
15
XLA10
NOMESCO Finland
NA
4.5
11.9
42
99
B01AB10
ATC
tinzaparin; parenteral
3.4
11.9
59
188
N39.4
ICD-10 Finland
Other specified urinary incontinence
3.5
11.8
57
178
JAH01
NOMESCO Finland
Laparoscopy
4.4
11.7
42
101
KH1AE
NOMESCO Finland
Urinary tract ultrasound examination
5.7
11.7
33
61
K63.2
ICD-10 Finland
Fistula of intestine
66.4
11.6
13
*
SPAT1125
SPAT
Stoma care and guidance
9.5
11.6
23
25
C54.11
ICD-10 Finland
Adenocarcinoma of the endometrium
9.5
11.6
23
25
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
2.7
11.6
84
345
G03GA02
ATC
human menopausal gonadotrophin; parenteral
14.0
11.5
19
14
N87.0
ICD-10 Finland
Mild cervical dysplasia
122.5
11.5
12
*
LCA10
NOMESCO Finland
Curettage of body of uterus
15.5
11.4
18
12
SPAT1262
SPAT
Handing over of treatment supplies
2.4
11.4
100
458
R19.0
ICD-10 Finland
Intra-abdominal and pelvic swelling, mass and lump
6.2
11.3
30
51
G04BD12
ATC
mirabegron; oral
3.4
11.2
54
169
A07EC02
ATC
mesalazine; oral, rectal
3.8
11.1
47
132
Z93.3
ICD-10 Finland
Colostomy status
14.3
11.0
18
13
R2110
NOMESCO Finland
Giving the first information
3.6
10.9
50
150
Z93.2
ICD-10 Finland
Ileostomy status
18.3
10.8
16
9
N99.4
ICD-10 Finland
Postprocedural pelvic peritoneal adhesions
28.7
10.8
14
5
JN3AA
NOMESCO Finland
Abdominal X-ray examination without contrast
4.7
10.8
36
81
WX320
NOMESCO Finland
Spinalanesthesy
2.2
10.7
127
668
JFF27
NOMESCO Finland
Laparoscopic sigmoidostomy
61.2
10.7
12
*
JFA98
NOMESCO Finland
Other transluminal endoscopic local operation on intestine
8.8
10.6
22
26
D25.0
ICD-10 Finland
Submucous leiomyoma of uterus
6.4
10.6
27
44
SPAT1153
SPAT
Removal of sutures
2.0
10.6
170
1013
K51.9
ICD-10 Finland
Ulcerative colitis, unspecified
5.2
10.5
32
65
K56.5
ICD-10 Finland
Intestinal adhesions [bands] with obstruction
8.0
10.5
23
30
K60.4
ICD-10 Finland
Rectal fistula
112.1
10.5
11
*
62620
ICD-8 Finland
Disorders of menstruation, Excessive
+∞
10.4
10
*
G03GA01
ATC
chorionic gonadotrophin; parenteral
8.4
10.4
22
27
JHA00
NOMESCO Finland
Anal or perianal incision
10.9
10.3
19
18
Y69
ICD-10 Finland
Unspecified misadventure during surgical and medical care
13.4
10.2
17
13
A07DA03
ATC
loperamide; oral
5.3
10.1
30
59
128
Kela drug reimbursment
Cancers of female genital organs
5.3
10.1
30
59
N84.1
ICD-10 Finland
Polyp of cervix uteri
40.8
10.0
12
*
TLC00
NOMESCO Finland
Insertion of intrauterine device
4.4
9.9
35
84
UJF12
NOMESCO Finland
Enteroscopy through intestinal stoma
20.5
9.8
14
7
WX110
NOMESCO Finland
Local anesthesy
1.8
9.8
369
2910
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
2.0
9.8
154
908
Z01.4
ICD-10 Finland
Gynaecological examination (general)(routine)
2.1
9.8
121
646
D01
ICPC
Abdominal pain/cramps general
2.8
9.7
65
255
WZB00
NOMESCO Finland
Telephone receipt or other advice
2.0
9.7
159
948
KH1CD
NOMESCO Finland
Very extensive urinary tract ultrasound examination
15.4
9.6
15
10
XF603
NOMESCO Finland
Direct intraarterial blood pressure measurement
4.6
9.5
32
73
T81.0
ICD-10 Finland
Haemorrhage and haematoma complicating a procedure, not elsewhere classified
3.5
9.5
43
129
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
2.8
9.4
62
239
N87.2
ICD-10 Finland
Severe cervical dysplasia, not elsewhere classified
101.7
9.4
10
*
C20.92
ICD-10 Finland
Malignant tumor of the rectum carcinoma of the adenoma
17.9
9.4
14
8
JAL21
NOMESCO Finland
Laparoscopic excision or destruction of lesion of peritoneum
30.6
9.4
12
*
N73.9
ICD-10 Finland
Female pelvic inflammatory disease, unspecified
12.6
9.4
16
13
TLW10
NOMESCO Finland
Transfer of fresh embryo
+∞
9.4
9
*
6173A
ICD-9 Finland
Endometriosis of pelvic peritoneum[ENDOMETRIOSIS SEROSAE PELVIS]
+∞
9.4
9
*
N97.0
ICD-10 Finland
Female infertility associated with anovulation
+∞
9.4
9
*
62650
ICD-8 Finland
Disorders of menstruation, Irregular
+∞
9.4
9
*
N75.1
ICD-10 Finland
Abscess of Bartholin gland
10.9
9.3
17
16
K51.5
ICD-10 Finland
Left sided colitis
5.6
9.3
26
48
N93.9
ICD-10 Finland
Abnormal uterine and vaginal bleeding, unspecified
14.0
9.2
15
11
N76.0
ICD-10 Finland
Acute vaginitis
3.6
9.2
41
121
TPH04
NOMESCO Finland
Cathetrisation of vein
2.1
9.2
119
648
G03DC03
ATC
lynestrenol; oral
6.4
9.2
23
37
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
2.4
9.2
79
357
Y83.8
ICD-10 Finland
Other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
5.8
9.2
25
45
R51.80
ICD-10 Finland
Headache
2.3
9.1
85
399
XJW99
NOMESCO Finland
Other investigative procedure on digestive system
37.3
9.0
11
*
JN2DM
NOMESCO Finland
Lower part of abdomen very extensive MRI examination with Tesla magnet
37.3
9.0
11
*
J01AA02
ATC
doxycycline; systemic
1.9
9.0
430
3610
JHD00
NOMESCO Finland
Anal dilatation
19.0
9.0
13
7
JF1AB
NOMESCO Finland
Passage examination of small bowell with X-ray
8.2
8.9
19
24
ZXE30
NOMESCO Finland
More than five and less than seven hours
3.5
8.8
40
120
Z71.3
ICD-10 Finland
Dietary counselling and surveillance
3.8
8.8
36
99
R10.1
ICD-10 Finland
Pain localized to upper abdomen
2.2
8.7
96
486
N81.4
ICD-10 Finland
Uterovaginal prolapse, unspecified
50.8
8.7
10
*
L02AE02
ATC
leuprorelin; implant, parenteral
16.6
8.6
13
8
JFH30
NOMESCO Finland
Total colectomy, mucosal proctectomy and ileoanal anastomosis without ileostomy
20.4
8.5
12
6
LWW96
NOMESCO Finland
Other reoperation in gynaecological surgery
91.4
8.4
9
*
N32.1
ICD-10 Finland
Vesicointestinal fistula
91.4
8.4
9
*
G03DC02
ATC
norethisterone; oral
2.2
8.4
94
479
R33
ICD-10 Finland
Retention of urine
4.6
8.4
28
64
61520
ICD-8 Finland
Other diseases of ovary and Fallopian tube, Cysta (cystis) follicularis ovarii (retentio)
+∞
8.4
8
*
N97.4
ICD-10 Finland
Female infertility associated with male factors
+∞
8.4
8
*
62530
ICD-8 Finland
Other diseases of uterus, Endometriosis ovarii
+∞
8.4
8
*
N97.1
ICD-10 Finland
Female infertility of tubal origin
+∞
8.4
8
*
6171A
ICD-9 Finland
Endometriosis of ovary
+∞
8.4
8
*
N87.1
ICD-10 Finland
Moderate cervical dysplasia
+∞
8.4
8
*
LCA16
NOMESCO Finland
Destruction of endometrium
+∞
8.4
8
*
LEC00
NOMESCO Finland
Partial excision of vagina
+∞
8.4
8
*
7353
FHL
Closure of the vaginal bladder fistula
+∞
8.4
8
*
JN4BD
NOMESCO Finland
Extensive body CT
2.4
8.3
71
319
SPAT1148
SPAT
Treatment of chronic ulcer or burn
2.4
8.2
71
321
1530
FHL
Urethrocystoscopy
14.8
8.2
13
9
T81.9
ICD-10 Finland
Unspecified complication of procedure
7.7
8.2
18
24
JFB47
NOMESCO Finland
Laparoscopic resection of sigmoid colon
7.7
8.2
18
24
G01AA10
ATC
clindamycin; vaginal
2.0
8.2
115
645
ZXK00
NOMESCO Finland
Conversion from percutaneous endoscopic to open procedure
11.9
8.1
14
12
KH1BD
NOMESCO Finland
Extensive urinary tract CT examination
11.9
8.1
14
12
N70.0
ICD-10 Finland
Acute salpingitis and oophoritis
11.9
8.1
14
12
LAF00
NOMESCO Finland
Unilateral salpingo-oophorectomy
11.9
8.1
14
12
LAC01
NOMESCO Finland
Laparoscopic excision of ovarian cyst
33.9
8.1
10
*
JFF26
NOMESCO Finland
Sigmoidostomy
33.9
8.1
10
*
R15
ICD-10 Finland
Faecal incontinence
5.1
8.0
24
49
A06AC51
ATC
ispaghula, combinations; systemic
3.6
8.0
35
103
K50.0
ICD-10 Finland
Crohn disease of small intestine
7.9
7.9
17
22
N06AB04
ATC
citalopram; systemic
1.9
7.9
127
748
Z3231
NOMESCO Finland
Registered nurse
1.8
7.8
142
871
M51.1
ICD-10 Finland
Lumbar and other intervertebral disc disorders with radiculopathy
2.3
7.8
75
355
H01CC01
ATC
ganirelix; parenteral
11.0
7.8
14
13
SPAT1144
SPAT
Treatment of reopened or infected surgical wound
3.0
7.8
45
161
N06AX11
ATC
mirtazapine; oral
1.8
7.8
169
1099
A07EA02
ATC
hydrocortisone; rectal
5.1
7.7
23
47
A02BC05
ATC
esomeprazole; systemic
1.7
7.7
213
1490
LC2HE
NOMESCO Finland
Hystero-salpingography with ultrasound
8.2
7.6
16
20
C20
ICD-10 Finland
Malignant neoplasm of rectum
18.7
7.6
11
6
326
Kela drug reimbursment
Adalimumab, golimumab, infliximab and ustekinumab (intestinal diseases)
18.7
7.6
11
6
121
Kela drug reimbursment
Severe hypofunction of sexual glands
5.6
7.6
21
39
JGB30
NOMESCO Finland
Abdominoperineal excision of rectum
25.4
7.6
10
*
N93.8
ICD-10 Finland
Other specified abnormal uterine and vaginal bleeding
25.4
7.6
10
*
JFG20
NOMESCO Finland
Closure of enterostomy with resection of exteriorised loop
25.4
7.6
10
*
LDC03
NOMESCO Finland
Conisation of cervix uteri using diathermy or laser
5.9
7.6
20
35
ZXC96
NOMESCO Finland
Robot assisted procedure
9.0
7.6
15
17
L04AX01
ATC
azathioprine; systemic
3.5
7.6
34
102
N02AB03
ATC
fentanyl; nasal, sublingual, transdermal
4.0
7.6
29
76
JEA00
NOMESCO Finland
Appendectomy
3.2
7.6
39
130
J01FF01
ATC
clindamycin; systemic
1.8
7.5
147
923
A49.9
ICD-10 Finland
Bacterial infection, unspecified
2.6
7.5
55
229
UJF30
NOMESCO Finland
Ileoscopy through colon
2.6
7.5
55
229
K51.8
ICD-10 Finland
Other ulcerative colitis
6.6
7.5
18
28
JFB00
NOMESCO Finland
Partial resection of small intestine
6.6
7.5
18
28
N30.9
ICD-10 Finland
Cystitis, unspecified
3.2
7.5
37
120
JFG30
NOMESCO Finland
Closure of colostomy with resection of exteriorised loop
81.1
7.4
8
*
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.6
7.4
271
2042
A03FA01
ATC
metoclopramide; systemic, rectal
1.8
7.4
137
847
G03GA06
ATC
follitropin beta; parenteral
8.5
7.4
15
18
K62.4
ICD-10 Finland
Stenosis of anus and rectum
+∞
7.3
7
*
LAA06
NOMESCO Finland
Transvaginal puncture of ovarian cyst
+∞
7.3
7
*
6198X
ICD-9 Finland
Fistulae involving female genital tract, Other specified fistulae involving female genital tract
+∞
7.3
7
*
62532
ICD-8 Finland
Other diseases of uterus, Endometriosis retro-cervicalis sive retrouterina
+∞
7.3
7
*
N80.81
ICD-10 Finland
Endometriosis in sacrouteral ligament
+∞
7.3
7
*
JH1CM
NOMESCO Finland
Perianal extensive MRI with 3 Tesla magnet
+∞
7.3
7
*
LEF51
NOMESCO Finland
Laparoscopic colpopexy after previous hysterectomy
+∞
7.3
7
*
LA2AE
NOMESCO Finland
Ultrasound examination of ovarian cyst
+∞
7.3
7
*
WX400
NOMESCO Finland
Inhalation anesthesy
3.7
7.3
30
84
R50.9
ICD-10 Finland
Fever, unspecified
2.3
7.3
71
339
WX002
NOMESCO Finland
Sedation and analgesia
1.9
7.2
108
617
5562A
ICD-9 Finland
Idiopathic proctocolitis, Ulcerative (chronic) proctitis
30.4
7.2
9
*
L02AB02
ATC
medroxyprogesterone; systemic (progestogens)
20.3
7.2
10
5
LCD11
NOMESCO Finland
Laparoscopically assisted vaginal hysterectomy
12.2
7.1
12
10
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
2.0
7.1
89
475
H02AB07
ATC
prednisone; oral
2.1
7.1
87
460
A04AA01
ATC
ondansetron; systemic, rectal
2.6
7.1
49
197
SPAT1083
SPAT
Initiation and monitoring of IV fluid therapy
3.9
7.1
27
71
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.7
7.1
210
1489
A06AD11
ATC
lactulose; oral
2.2
7.0
72
353
1410
FHL
Laparoscopy
5.3
7.0
20
39
JF1CG
NOMESCO Finland
Extensive MRI of small bowel
14.0
6.9
11
8
N06AX16
ATC
venlafaxine; oral
2.1
6.9
80
414
XKD03
NOMESCO Finland
Urethral pressure profilometry
4.9
6.9
21
44
8380/3-C54.1
ICD-O-3
Endometrioid adenocarcinoma, NOS, of endometrium
8.4
6.9
14
17
R10.2
ICD-10 Finland
Pelvic and perineal pain
6.8
6.9
16
24
S18
ICPC
Laceration/cut
1.6
6.8
208
1484
WX290
NOMESCO Finland
Other blockade of nerve
1.6
6.8
226
1647
N05CF02
ATC
zolpidem; oral
1.9
6.8
103
592
TPH90
NOMESCO Finland
Removal of fixed intravenous catheter
7.3
6.7
15
21
JN2CM
NOMESCO Finland
Lower part of abdomen extensive MRI examination with Tesla magnet
22.8
6.7
9
*
JN2BD
NOMESCO Finland
Extensive CT exmaniation of lower part of abdomen
22.8
6.7
9
*
SPAT1255
SPAT
Intravenous administration of medicine
2.9
6.6
38
137
K51.1
ICD-10 Finland
Ulcerative (chronic) ileocolitis
10.2
6.6
12
12
C05AA08
ATC
fluocortolone; rectal, topical
2.0
6.6
81
428
SPAT1301
SPAT
No procedures
1.7
6.5
157
1044
R32
ICD-10 Finland
Unspecified urinary incontinence
4.6
6.5
21
47
U02
ICPC
Urinary frequency/urgency
2.1
6.5
77
404
I84.2
ICD-10 Finland
Internal hemorrhoids without complication
2.8
6.4
41
156
JGB10
NOMESCO Finland
Partial proctectomy and end colostomy
70.6
6.4
7
*
JHD96
NOMESCO Finland
Other incision of anal sphincter
70.6
6.4
7
*
JWF00
NOMESCO Finland
Reoperation for insufficiency of anastomosis or suture in gastroenterological surgery
70.6
6.4
7
*
SPAT1263
SPAT
Sampling
1.6
6.4
216
1578
N06AX21
ATC
duloxetine; oral
2.2
6.4
63
303
G03DA04
ATC
progesterone; systemic, rectal, vaginal
4.1
6.4
23
58
XKD06
NOMESCO Finland
Physiologic investigation of micturition
5.6
6.3
17
31
WD125
NOMESCO Finland
Demanding cystostatic therapy of methastized malignancy
3.1
6.3
33
112
WX892
NOMESCO Finland
Monitored bed care
2.7
6.3
42
166
KBV10
NOMESCO Finland
Removal of stent from ureter
11.2
6.3
11
10
K51.0
ICD-10 Finland
Ulcerative (chronic) pancolitis
9.4
6.3
12
13
KBJ10
NOMESCO Finland
Cutaneous ureteroenterostomy
18.3
6.3
9
5
N94.5
ICD-10 Finland
Secondary dysmenorrhoea
18.3
6.3
9
5
K80.2
ICD-10 Finland
Calculus of gallbladder without cholecystitis
2.1
6.3
71
362
M01AE03
ATC
ketoprofen; systemic, rectal
1.6
6.3
194
1383
TLW00
NOMESCO Finland
Insemination
+∞
6.3
6
*
N36.1
ICD-10 Finland
Urethral diverticulum
+∞
6.3
6
*
62550
ICD-8 Finland
NA
+∞
6.3
6
*
LEF53
NOMESCO Finland
Vaginal colpopexy after previous hysterectomy
+∞
6.3
6
*
N80.5
ICD-10 Finland
Endometriosis of intestine
+∞
6.3
6
*
N80.89
ICD-10 Finland
Endometriosis with other specified or multiple localization
+∞
6.3
6
*
62800
ICD-8 Finland
Sterility, female, Sterilitas primaria
+∞
6.3
6
*
S37.1
ICD-10 Finland
Injury of ureter
+∞
6.3
6
*
6173B
ICD-9 Finland
Endometriosis of pelvic peritoneum[ENDOMETRIOSIS RETROUTERINA]
+∞
6.3
6
*
K63.0
ICD-10 Finland
Abscess of intestine
+∞
6.3
6
*
TLW12
NOMESCO Finland
Insertion of frozen embryo
+∞
6.3
6
*
LDW96
NOMESCO Finland
Other operation on cervix uteri
+∞
6.3
6
*
JFG73
NOMESCO Finland
Excision of ileal pelvic pouch
+∞
6.3
6
*
LEE10
NOMESCO Finland
Repair of vagina using graft or flap
+∞
6.3
6
*
XKC03
NOMESCO Finland
Water cystometry
4.0
6.3
23
59
L01BC06
ATC
capecitabine; oral
3.2
6.3
30
96
A07EA06
ATC
budesonide; oral, local oral
3.4
6.2
28
85
JFF11
NOMESCO Finland
Laparoscopic loop enterostomy
27.0
6.2
8
*
JFA58
NOMESCO Finland
Endoscopic dilatation of colon
27.0
6.2
8
*
JHD30
NOMESCO Finland
Incomplete incision of fistula-in-ano
27.0
6.2
8
*
LAE11
NOMESCO Finland
Unilateral laparoscopic oophorectomy
27.0
6.2
8
*
JGC01
NOMESCO Finland
Laparoscopic rectopexy
27.0
6.2
8
*
KA1FN
NOMESCO Finland
Isotope renography
12.7
6.1
10
8
JGB06
NOMESCO Finland
Partial proctectomy with total excision of mesorectum
12.7
6.1
10
8
Z35.0
ICD-10 Finland
Supervision of pregnancy with history of infertility
12.7
6.1
10
8
JN4AD
NOMESCO Finland
Body CT examination
2.5
6.1
46
194
JAD11
NOMESCO Finland
Laparoscopic repair of incisional hernia
8.7
6.1
12
14
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
2.0
6.1
74
392
Mortality – FinRegistry
↥Association
Association between endpoint N14_FEMGENFISTUL and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| N14_FEMGENFISTUL | 2.204 [1.92, 2.53] | < 0.001 |
| Birth year | 0.996 [0.99, 1.0] | 0.35 |
During the follow-up period (1.1.1998 — 31.12.2019), 857 out of 3218 females with N14_FEMGENFISTUL died.
Males
No dataMortality risk
Mortality risk for people of age
years, who have N14_FEMGENFISTUL.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.297% | No data |
| 5 | 1.464% | No data |
| 10 | 3.543% | No data |
| 15 | 6.39% | No data |
| 20 | 11.47% | No data |
Relationships between endpoints
↥Index endpoint: N14_FEMGENFISTUL – Fistulae involving female genital tract
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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