Disorders of pituitary gland, other and/or unspecified

E4_PITUDISNAS

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 E23.6, E23.7
  • Hospital discharge: ICD-9 253[8-9]
  • Hospital discharge: ICD-8 2539
  • Hospital discharge: excluded ICD-8 25390
  • Cause of death: ICD-10 E23.6, E23.7
  • Cause of death: ICD-9 253[8-9]
  • Cause of death: ICD-8 2539
  • Cause of death: excluded ICD-8 25390

2 out of 7 registries used, show all original rules.

211

4. Check minimum number of events

None

211

5. Include endpoints

None

211

6. Filter based on genotype QC (FinnGen only)

211

Control definitions (FinnGen only)

Control exclude
E4_ENDOGLAND

Extra metadata

Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF2

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 1524 908 598
Only index persons 1235 751 484
Unadjusted period prevalence (%)
Whole population 0.02 0.03 0.02
Only index persons 0.02 0.03 0.02
Median age at first event (years)
Whole population 43.56 42.80 44.54
Only index persons 39.94 38.95 41.48

-FinnGen-

Key figures

All Female Male
Number of individuals 211 130 81
Unadjusted period prevalence (%) 0.04 0.04 0.04
Median age at first event (years) 42.83 40.75 46.15

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
182
Matched controls
1820
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
E23.6
ICD-10 Finland
Other disorders of pituitary gland
+∞
98.0
85
*
H02AB09
ATC
hydrocortisone; systemic
209.8
68.3
67
5
101
Kela drug reimbursment
Anterior pituitary hypofunction
+∞
58.5
53
*
E23.00
ICD-10 Finland
Panhypopituitarism
+∞
50.4
46
*
AA4CG
NOMESCO Finland
Extensive MRI examination of sella turcica with high intensity magnet
296.4
46.2
45
*
D35.2
ICD-10 Finland
Benign neoplasm: Pituitary gland
203.4
46.2
46
*
E23.7
ICD-10 Finland
Disorder of pituitary gland, unspecified
+∞
45.8
42
*
AAE10
NOMESCO Finland
Transsphenoidal total or partial excision of intracranial lesion
+∞
28.9
27
*
102
Kela drug reimbursment
Diabetes insipidus
+∞
27.8
26
*
H03AA01
ATC
levothyroxine sodium; systemic
5.7
24.4
90
267
25398
ICD-8 Finland
Diseases of pituitary gland, Alii definiti
+∞
23.4
22
*
H01BA02
ATC
desmopressin; nasal, systemic, sublingual
50.2
22.1
26
6
25399
ICD-8 Finland
Diseases of pituitary gland, Other and unspecified
+∞
21.3
20
*
D44.3
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Pituitary gland
+∞
21.3
20
*
E22.1
ICD-10 Finland
Hyperprolactinaemia
+∞
19.1
18
*
G03BA03
ATC
testosterone; systemic, rectal, sublingual, transdermal
11.6
17.6
33
34
N04BC06
ATC
cabergoline; oral (dopamine agonists)
+∞
16.9
16
*
H01AC01
ATC
somatropin; parenteral
+∞
15.9
15
*
E23.2
ICD-10 Finland
Diabetes insipidus
+∞
15.9
15
*
E23.09
ICD-10 Finland
Pituitary insufficiency NOS
+∞
12.6
12
*
G02CB01
ATC
bromocriptine; systemic
19.8
12.3
18
10
301
Kela drug reimbursment
Growth hormone
+∞
11.6
11
*
AA4BG
NOMESCO Finland
MRI examination of sella turcica with high intensity magnet
127.7
11.6
12
*
Z03.80
ICD-10 Finland
Observation for other suspected diseases and conditions
11.6
10.6
19
18
E34.9
ICD-10 Finland
Endocrine disorder, unspecified
116.4
10.5
11
*
E23.05
ICD-10 Finland
Lack of TSH
+∞
10.5
10
*
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
5.4
10.5
32
69
XCK00
NOMESCO Finland
Perimetry
5.6
8.4
24
48
2532A
ICD-9 Finland
Disorders of the pituitary gland and its hypothalamic control, Panhypopituitarism[PANHYPOPITUITARISMUS]
+∞
8.4
8
*
E23.01
ICD-10 Finland
Isolated deficiency of growth hormone
+∞
8.4
8
*
2538X
ICD-9 Finland
Disorders of the pituitary gland and its hypothalamic control, Other disorders of the pituitary and other syndromes of diencephalohypophyseal origin[MORBUS HYPOPHYSEOS SEU HYPOTHALAMI ALIA]
+∞
8.4
8
*
25320
ICD-8 Finland
Diseases of pituitary gland, Chromophobe adenoma, pituitary
+∞
8.4
8
*
AA4CM
NOMESCO Finland
Extensive MRI examination of sella turcica with 3 Tesla magnet
+∞
8.4
8
*
E23.03
ICD-10 Finland
Lack of ACTH
+∞
8.4
8
*
E23.04
ICD-10 Finland
Hypogonadotropic hypogonadism
83.3
7.5
8
*
2539X
ICD-9 Finland
Disorders of the pituitary gland and its hypothalamic control, Unspecified
+∞
7.3
7
*
E23
ICD-10 Finland
Hypofunction and other disorders of pituitary gland
+∞
7.3
7
*
22620
ICD-8 Finland
Benign neoplasm of endocrine glands, Pituitary gland and craniopharyngeal duct (pouch)
+∞
7.3
7
*
ZXC86
NOMESCO Finland
Use of endoscopic device
41.6
6.8
8
*
E22.0
ICD-10 Finland
Acromegaly and pituitary gigantism
+∞
6.3
6
*
D35.30
ICD-10 Finland
Craniopharyngoma
+∞
6.3
6
*
AA4DG
NOMESCO Finland
Very extensive MRI examination of sella turcica with high intensity magnet
+∞
6.3
6
*
E23.06
ICD-10 Finland
Empty sella
+∞
6.3
6
*
E23.08
ICD-10 Finland
Hypopituitarism
+∞
6.3
6
*
K08.1
ICD-10 Finland
Loss of teeth due to accident, extraction or local periodontal disease
3.7
6.2
26
78
121
Kela drug reimbursment
Severe hypofunction of sexual glands
9.1
6.2
12
14

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
unit
cases
controls
-log10(p)
N cases
N controls
(3036481) Cortisol [Moles/volume] in Serum or Plasma
108
147
14.00
83.69
5.8
1.8
nmol/l
297.2
389.5
3.74
102
135
(3035637) Corticotropin [Mass/volume] in Plasma
42
15
34.71
63.66
1.5
1.2
—
—
—
0
0
(3009214) Lutropin [Units/volume] in Serum or Plasma
43
45
11.75
38.15
2.1
1.2
u/l
4.6
8.0
1.21
32
35
(3026989) Triiodothyronine (T3) Free [Moles/volume] in Serum or Plasma
50
94
6.66
26.93
2.8
3.2
pmol/l
4.1
4.6
2.21
44
84
(3023323) Follitropin [Units/volume] in Serum or Plasma
41
76
6.45
22.19
1.7
1.2
iu/l
24.5
25.8
0.07
26
65
(3017446) Testosterone [Moles/volume] in Serum or Plasma
49
119
5.06
19.68
5.3
2.0
nmol/l
10.7
14.2
2.49
44
110
(44816844) Macroprolactin [Units/volume] in Serum or Plasma
15
17
9.42
12.15
4.4
1.4
—
—
—
0
0
(3048816) Calcium.ionized [Moles/volume] adjusted to pH 7.4 in Blood
40
122
3.81
11.65
5.6
3.0
mmol/l
1.2
1.2
0.77
35
107
(4027681)
13
13
10.59
11.45
1.4
1.2
—
—
—
0
0
(3002030) Lymphocytes/100 leukocytes in Blood
131
818
2.59
10.08
6.7
5.7
%
29.2
28.2
0.40
126
757
(3018010) Neutrophils/100 leukocytes in Blood
130
812
2.57
9.95
6.0
5.5
%
56.9
56.9
0.01
125
757
(3029080) Hemoglobin [Entitic mass] in Reticulocytes
13
16
8.59
9.84
2.2
1.6
pg
33.1
31.7
0.32
13
16
(3018418) pH of Serum or Plasma
93
506
2.50
9.46
5.0
3.4
ph
7.4
7.4
0.87
30
90
(3021347) Calcium.ionized [Moles/volume] in Serum or Plasma
120
735
2.47
9.39
12.2
5.7
mmol/l
1.2
1.2
0.12
111
671
(3044290) Cell count panel - Cerebral spinal fluid
18
34
5.69
9.34
1.4
1.4
—
—
—
0
0
(3016431) Calcium.ionized [Moles/volume] adjusted to pH 7.4 in Serum or Plasma
126
793
2.46
9.23
12.9
6.6
mmol/l
1.2
1.2
0.04
95
665
(3006504) Eosinophils/100 leukocytes in Blood
126
794
2.46
9.19
6.6
5.7
%
2.5
2.8
0.81
119
734
(3019069) Monocytes/100 leukocytes in Blood
126
797
2.44
9.07
6.7
5.9
%
8.8
8.4
0.45
121
742
(3022096) Basophils/100 leukocytes in Blood
122
769
2.39
8.74
6.7
5.7
%
0.6
0.7
0.20
117
710
(40761536) Microorganisms panel - Urine sediment
37
130
3.24
8.59
4.9
4.0
—
—
—
0
0
(3026782) Osmolality of Urine
65
311
2.58
8.55
4.0
2.7
mosm/kgh2o
500.9
539.6
0.60
55
262
(3019198) Lymphocytes [#/volume] in Blood
133
882
2.37
8.32
6.1
5.6
e9/l
1.9
2.0
0.04
120
781
(1001509) Gas and Carbon monoxide and Electrolytes panel - Arterial blood
10
12
8.70
7.64
3.4
2.0
—
—
—
0
0
(3016018) Differential panel - Cerebral spinal fluid
10
12
8.70
7.64
1.4
1.0
—
—
—
0
0
(3017181) Myelocytes/100 leukocytes in Blood
36
134
3.03
7.56
4.0
4.3
%
0.9
1.0
0.02
16
30
(3025159) Blasts/100 leukocytes in Blood
34
123
3.10
7.49
4.1
4.5
%
0.0
0.0
0.00
13
24
(40759883) Oligoclonal Bands IgG [Presence] in Cerebral spinal fluid by Isoelectric focusing
12
9
14.04
7.48
1.3
1.0
—
—
—
0
0
(3006315) Basophils [#/volume] in Blood
128
861
2.24
7.39
6.1
5.5
e9/l
0.0
0.0
0.10
112
747
(3021440) Promyelocytes/100 leukocytes in Blood
34
124
3.08
7.39
4.1
4.5
%
0.1
0.1
0.35
14
27
(3024561) Albumin [Mass/volume] in Serum or Plasma
112
716
2.20
7.32
7.8
4.6
g/l
35.5
36.0
0.37
104
672
(42870588) Differential panel, method unspecified - Blood
92
545
2.22
7.26
6.5
5.4
—
—
—
0
0
(3014973) Borrelia burgdorferi IgM Ab [Units/volume] in Cerebral spinal fluid
11
16
7.20
7.22
1.0
1.0
—
—
—
0
0
(3001604) Monocytes [#/volume] in Blood
127
860
2.20
7.11
6.1
5.5
e9/l
0.6
0.6
0.55
111
743
(3027475) Erythrocytes [#/volume] in Cerebral spinal fluid
18
44
4.38
6.97
1.5
1.5
e6/l
9.4
22.5
0.63
12
38
(3016543) Leukocytes [#/volume] in Cerebral spinal fluid
18
44
4.38
6.97
1.3
1.3
e6/l
58.3
3.2
0.46
12
38
(3002179) Metamyelocytes/100 leukocytes in Blood
32
117
3.05
6.91
4.2
4.3
%
0.3
0.3
0.00
12
18
(3008486) Thyroxine (T4) free [Moles/volume] in Serum or Plasma
170
1311
2.53
6.79
8.0
3.9
pmol/l
15.2
14.8
1.06
163
1193
(3009340) Metanephrine [Moles/volume] in Serum or Plasma
10
14
7.45
6.76
1.5
1.3
nmol/l
—
—
—
0
0
(3011166) Borrelia burgdorferi Ab [Presence] in Cerebral spinal fluid
10
14
7.45
6.76
1.0
1.0
—
—
—
0
0
(3021589) Normoblasts [#/volume] in Blood
115
760
2.13
6.72
14.8
8.9
e9/l
0.0
0.0
0.30
97
617
(3013115) Eosinophils [#/volume] in Blood
128
886
2.13
6.56
6.3
5.7
e9/l
0.2
0.2
0.21
112
787
(3010380) Borrelia burgdorferi IgG Ab [Units/volume] in Cerebral spinal fluid
10
15
6.95
6.37
1.0
1.0
—
—
—
0
0
(3012320) Pathologist interpretation of Cerebral spinal fluid tests
6
0
+∞
6.28
1.2
0.0
—
—
—
0
0
(3032080) INR in Blood by Coagulation assay
99
636
2.05
6.06
8.1
7.4
inr
1.1
1.2
0.46
38
187
(3032155) Metanephrine Free [Moles/volume] in Serum or Plasma
10
16
6.51
6.01
1.5
1.3
—
—
—
0
0
(3042596) Human coronavirus RNA [Presence] in Specimen by NAA with probe detection
10
16
6.51
6.01
1.2
1.3
—
—
—
0
0
(3044938) Influenza virus A RNA [Presence] in Specimen by NAA with probe detection
51
255
2.32
5.89
1.7
1.7
—
—
—
0
0
(3013650) Neutrophils [#/volume] in Blood by Automated count
137
1000
2.06
5.77
9.1
9.1
e9/l
4.0
4.0
0.07
122
873
(3020565) Legionella pneumophila DNA [Presence] in Specimen by NAA with probe detection
10
17
6.13
5.68
1.3
1.5
—
—
—
0
0
(3014162) Mycobacterium tuberculosis DNA [Presence] in Specimen by NAA with probe detection
16
42
4.04
5.65
1.9
2.0
—
—
—
0
0
(40764127) Haemophilus influenzae DNA [Presence] in Specimen by NAA with probe detection
9
7
13.35
5.63
1.3
1.4
—
—
—
0
0
(40767503) Oxygen content in Capillary blood by calculation
13
30
4.55
5.37
3.8
1.8
%
16.2
16.5
—
6
10
(3023410) Appearance of Cerebral spinal fluid
10
18
5.78
5.37
1.5
1.7
—
—
—
0
0
(3012477) Bordetella pertussis DNA [Presence] in Specimen by NAA with probe detection
10
18
5.78
5.37
1.3
1.5
—
—
—
0
0
(3037875) Bordetella parapertussis DNA [Presence] in Specimen by NAA with probe detection
9
8
11.68
5.34
1.3
1.4
—
—
—
0
0
(3032699) Streptococcus pneumoniae DNA [Presence] in Specimen by NAA with probe detection
9
8
11.68
5.34
1.3
1.6
—
—
—
0
0
(3010566) Parathyrin.intact [Moles/volume] in Serum or Plasma
11
22
5.22
5.32
6.5
1.5
—
—
—
0
0
(4035726)
33
141
2.59
5.32
1.4
1.3
—
—
—
0
0
(3043924) Respiratory syncytial virus RNA [Identifier] in Specimen by NAA with probe detection
38
175
2.43
5.24
1.7
1.7
—
—
—
0
0
(3004789) Transferrin [Mass/volume] in Serum or Plasma
45
228
2.24
4.99
3.5
2.1
g/l
2.3
2.4
0.63
40
207
(3038288) Influenza virus B RNA [Presence] in Specimen by NAA with probe detection
38
179
2.37
4.98
1.7
1.7
—
—
—
0
0
(3019902) Methicillin resistant Staphylococcus aureus [Presence] in Specimen by Organism specific culture
37
173
2.38
4.93
4.1
3.0
—
—
—
0
0
(3035995) Alkaline phosphatase [Enzymatic activity/volume] in Serum or Plasma
165
1327
2.12
4.86
9.0
7.3
u/l
76.5
78.6
0.26
160
1239
(3051552) Clostridioides difficile toxin genes [Presence] in Stool by NAA with probe detection
27
112
2.62
4.61
2.0
1.6
—
—
—
0
0
(3030692) Respiratory virus DNA+RNA [Identifier] in Specimen by NAA with probe detection
10
21
4.95
4.58
1.2
1.2
—
—
—
0
0
(40765161) Human bocavirus DNA [Presence] in Specimen by NAA with probe detection
10
21
4.95
4.58
1.2
1.2
—
—
—
0
0
(40768797) Stomach Pathology biopsy report
44
229
2.16
4.55
1.2
1.3
—
—
—
0
0
(3040853) Adenovirus DNA [Identifier] in Specimen by NAA with probe detection
12
30
4.18
4.50
1.2
1.3
—
—
—
0
0
(3042194) Human metapneumovirus RNA [Presence] in Specimen by NAA with probe detection
12
30
4.18
4.50
1.2
1.3
—
—
—
0
0
(3002482) Mycoplasma pneumoniae DNA [Presence] in Specimen by NAA with probe detection
11
26
4.41
4.41
1.3
1.3
—
—
—
0
0
(40760892) CBC W Ordered Manual Differential panel - Blood
66
405
1.92
4.33
5.7
4.8
—
—
—
0
0
(3030467) Casts [#/volume] in Urine by Automated count
72
457
1.87
4.25
4.3
3.0
e6/l
0.3
0.3
0.25
57
341
(3023368) Bacteria identified in Blood by Culture
67
418
1.88
4.16
6.5
4.5
—
—
—
0
0
(3005702) Mycobacterium sp identified in Specimen by Organism specific culture
12
32
3.92
4.14
1.5
1.4
—
—
—
0
0
(3013707) Erythrocyte sedimentation rate by Westergren method
159
1292
1.94
4.14
4.7
4.0
mm/h
12.1
11.3
0.31
153
1188
(40763571) Iron/Transferrin [Ratio] in Serum or Plasma
41
217
2.10
4.04
3.5
2.2
%
19.2
22.5
0.97
36
186
(1616796) Gas panel - Central venous blood
12
33
3.80
3.98
9.2
1.5
—
—
—
0
0
(3009201) Thyrotropin [Units/volume] in Serum or Plasma
183
1572
2.24
3.94
7.0
4.7
mu/l
1.4
1.9
6.65
169
1443
(3011391) Calcitriol [Moles/volume] in Serum or Plasma
8
11
7.51
3.89
1.3
1.4
—
—
—
0
0
(3041096) Erythrocytes [Presence] in Urine by Automated
71
465
1.79
3.72
4.7
3.2
—
—
—
0
0
(36305247) Microscopic observation [Identifier] in Isolate by Gram stain
13
40
3.40
3.69
2.8
1.6
—
—
—
0
0
(3032035) Polymorphonuclear cells/100 leukocytes in Blood
11
30
3.81
3.69
9.6
3.7
%
48.5
60.4
0.89
11
30
(3031478) Chlamydophila pneumoniae DNA [Presence] in Specimen by NAA with probe detection
9
17
5.48
3.55
1.3
1.3
—
—
—
0
0
(3029287) Urinalysis microscopic panel [#/volume] - Urine by Automated count
84
585
1.72
3.52
4.5
2.9
—
—
—
0
0
(3029187) Natriuretic peptide.B prohormone N-Terminal [Mass/volume] in Serum or Plasma
70
463
1.77
3.52
2.7
2.9
ng/l
4957.4
1283.4
0.64
62
387
(3009035) Cobalamin (Vitamin B12) [Moles/volume] in Serum or Plasma
54
330
1.86
3.52
1.8
1.7
pmol/l
496.6
451.0
0.51
48
280
(40764126) Parainfluenza virus RNA [Presence] in Specimen by NAA with probe detection
8
14
5.89
3.37
1.3
1.3
—
—
—
0
0
(3010838) Calcium [Moles/time] in 24 hour Urine
6
7
8.78
3.28
1.0
1.1
—
—
—
0
0
(3004809) Band form neutrophils/100 leukocytes in Blood
9
19
4.90
3.27
4.9
4.1
%
0.7
1.3
—
9
14
(3008909) Norovirus RNA [Presence] in Stool by NAA with probe detection
14
49
2.99
3.26
1.4
1.1
—
—
—
0
0
(3012220) Varicella zoster virus IgM Ab [Presence] in Serum by Immunoassay
8
15
5.50
3.22
1.4
1.1
—
—
—
0
0
(3016914) Bacteria identified in Cerebral spinal fluid by Culture
8
15
5.50
3.22
1.5
1.1
—
—
—
0
0
(3002582) Erythrocytes [#/volume] in Urine
74
508
1.70
3.22
4.5
3.0
e6/l
27.4
158.1
0.51
58
387
(43054903) Holo-transcobalamin II [Moles/volume] in Serum
91
664
1.65
3.12
2.0
1.9
pmol/l
95.8
97.9
0.16
47
325
(3035999) Lactate [Moles/volume] in Cerebral spinal fluid
7
12
5.99
3.04
1.4
1.1
mmol/l
2.2
1.8
—
7
12
(3042936) Bacteria identified in Isolate by Culture
40
232
1.89
3.04
2.9
2.2
—
—
—
0
0
(3022806) Fractional oxyhemoglobin in Capillary blood
9
21
4.43
3.03
2.7
1.5
%
86.6
89.7
—
9
21
(3012565) Volume of 24 hour Urine
5
5
10.20
2.99
1.2
3.2
ml
2190.0
2459.0
—
5
5
(3023150) Myeloperoxidase Ab [Units/volume] in Serum
10
30
3.45
2.94
1.2
1.2
—
—
—
0
0
(3030905) Polymorphonuclear cells [#/volume] in Blood
10
30
3.45
2.94
8.0
3.1
e9/l
4.1
5.0
—
10
30
(3023520) Reticulocytes [#/volume] in Blood
25
124
2.15
2.90
3.4
2.5
e9/l
71.1
70.1
0.05
20
90
(40762485) Glomerular basement membrane Ab [Units/volume] in Serum by Immunoassay
6
9
6.82
2.88
1.2
1.1
—
—
—
0
0
(3037467) Urinalysis macro (dipstick) panel - Urine
143
1183
1.65
2.87
5.9
4.3
—
—
—
0
0
(3033386) Bacteria [Presence] in Cerebral spinal fluid by Light microscopy
5
6
8.50
2.76
1.4
1.0
—
—
—
0
0
(3008733) Herpes simplex virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
5
6
8.50
2.76
1.0
1.0
—
—
—
0
0
(4062490)
8
19
4.33
2.70
3.6
1.3
—
—
—
0
0
(3000850) Epithelial cells [#/volume] in Urine
51
333
1.70
2.61
4.0
2.4
e6/l
5.1
4.6
0.17
46
296
(36304419) Bacteria [Presence] in Urine
65
454
1.62
2.57
4.4
2.8
—
—
—
0
0
(3028369) Herpes simplex virus 1+2 DNA [Presence] in Specimen by NAA with probe detection
6
11
5.58
2.56
1.0
1.1
—
—
—
0
0
(3003396) Base excess in Arterial blood by calculation
31
176
1.89
2.51
21.5
9.8
mmol/l
0.6
1.5
0.48
26
141
(3051714) Fibrin D-dimer FEU [Mass/volume] in Platelet poor plasma
56
381
1.64
2.45
1.5
1.7
mg/l
0.8
1.2
1.05
40
293
(3007853) Bacteria identified in Skin by Aerobe culture
31
179
1.86
2.39
2.5
1.6
—
—
—
0
0
(21493690) Lymphocyte T-cell and B-cell and Natural killer subsets panel - Blood
5
8
6.37
2.38
3.6
2.3
—
—
—
0
0
(3042631) Mycobacterium sp identified in Specimen
7
17
4.22
2.38
2.3
3.0
—
—
—
0
0
(3015377) Calcium [Moles/volume] in Serum or Plasma
77
572
1.55
2.31
4.9
3.4
mmol/l
2.3
2.4
0.72
68
498
(3009261) Glucose [Presence] in Urine by Test strip
107
854
1.51
2.30
5.0
3.6
estimate
0.0
0.0
0.00
33
142
(40763086) Leukocyte esterase [Presence] in Urine by Automated test strip
87
665
1.52
2.29
5.6
3.6
—
—
—
0
0
(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
5
9
5.66
2.22
1.0
1.1
—
—
—
0
0
(3012516) Albumin [Mass/volume] in Urine
65
469
1.56
2.21
2.6
3.1
mg/l
700.5
200.0
0.32
41
285
(3014148) Varicella zoster virus Ab [Titer] in Serum
6
14
4.38
2.16
1.3
1.1
—
—
—
0
0
(3035350) Ketones [Presence] in Urine by Test strip
106
852
1.49
2.16
4.9
3.5
estimate
0.0
0.0
0.00
31
152
(3022145) Colonoscopy Study observation
32
193
1.78
2.15
1.2
1.4
—
—
—
0
0
(3019309) Folate [Moles/volume] in Red Blood Cells
44
292
1.64
2.10
1.8
1.6
nmol/l
1324.7
1159.9
0.51
35
212
(3021601) Nitrite [Presence] in Urine by Test strip
105
846
1.48
2.09
7.3
4.8
estimate
0.0
0.0
0.00
32
152
(3012336) Haptoglobin [Mass/volume] in Serum or Plasma
14
63
2.31
2.06
1.1
2.2
g/l
1.7
1.5
0.25
14
52
(3037522) Nuclear Ab [Titer] in Serum
37
239
1.66
1.96
1.4
1.4
titre
280.0
458.9
—
6
53
(3015635) Cytomegalovirus IgM Ab [Units/volume] in Serum or Plasma
8
27
3.04
1.95
1.6
1.1
—
—
—
0
0
(3018095) Leukocytes [#/volume] in Urine
78
599
1.48
1.95
5.0
3.6
e6/l
17.6
93.2
1.00
59
420
(3044889) 12 lead EKG panel
140
1205
1.48
1.93
4.1
3.6
—
—
—
0
0
(3013721) Aspartate aminotransferase [Enzymatic activity/volume] in Serum or Plasma
77
591
1.48
1.92
4.0
3.3
u/l
48.3
31.4
1.03
71
564
(3042111) Morphology [Interpretation] in Bone marrow Narrative
7
22
3.25
1.89
1.4
1.4
—
—
—
0
0
(3048689) Calprotectin [Mass/mass] in Stool
34
217
1.68
1.89
2.1
2.4
ug/g
112.5
120.8
0.10
25
172
(3044640) Blood type and Crossmatch panel - Blood
69
521
1.48
1.86
2.3
2.1
—
—
—
0
0
(3018559) Microscopic observation [Identifier] in Buccal smear by Cyto stain
6
17
3.60
1.85
1.5
1.0
—
—
—
0
0
(21494755) Public health laboratory ask at order entry panel
9
193
0.44
1.84
1.7
1.4
—
—
—
0
0
(3043362) Influenza virus B Ag [Presence] in Nasopharynx by Immunoassay
9
35
2.64
1.82
1.4
1.5
—
—
—
0
0
(3046524) Influenza virus A Ag [Presence] in Nasopharynx by Immunoassay
9
35
2.64
1.82
1.4
1.5
—
—
—
0
0
(3017918) Cytomegalovirus IgG Ab [Titer] in Serum or Plasma
8
29
2.83
1.81
1.6
1.2
—
—
—
0
0
(3020682) Albumin/Creatinine [Ratio] in Urine
66
497
1.48
1.80
3.9
3.8
mg/mmol
1.3
9.3
4.31
45
306
(3019050) Tissue transglutaminase IgA Ab [Units/volume] in Serum
54
392
1.51
1.75
1.3
1.2
u/ml
0.8
1.0
0.31
16
105
(40769539) Bacteria identified based on 16S rRNA gene [Identifier] in Specimen by Sequencing
8
30
2.73
1.74
1.1
1.4
—
—
—
0
0
(3025941) Bacteria identified in Stool by Culture
18
97
1.94
1.72
1.3
1.2
—
—
—
0
0
(3004410) Hemoglobin A1c/Hemoglobin.total in Blood
177
1615
1.60
1.71
6.5
5.4
mmol/mol
39.9
39.7
0.08
170
1513
(3013742) Prealbumin [Mass/volume] in Serum or Plasma
23
135
1.79
1.71
2.7
2.6
g/l
0.2
0.2
0.68
23
124
(3030306) Epithelial cells.non-squamous [#/volume] in Urine by Automated count
41
282
1.56
1.70
3.4
2.7
e6/l
0.9
0.8
0.08
22
163
(3021879) Hepatitis B virus core Ab [Presence] in Serum
21
120
1.83
1.69
1.4
1.5
—
—
—
0
0
(3038177) Helicobacter pylori Ab [Presence] in Serum
6
19
3.22
1.67
1.2
1.2
—
—
—
0
0
(4268621)
7
25
2.86
1.66
1.7
1.9
—
—
—
0
0
(46235355) HIV 1 and 2 tests - Meaningful Use set
40
275
1.56
1.66
2.0
1.8
—
—
—
0
0
(3045142) Bone marrow Pathology biopsy report
5
14
3.63
1.62
1.0
1.1
—
—
—
0
0
(3007164) IgA [Mass/volume] in Serum or Plasma
49
356
1.49
1.58
1.4
1.3
g/l
2.4
2.5
0.04
33
205
(3027238) Thyroperoxidase Ab [Units/volume] in Serum or Plasma
20
116
1.80
1.55
1.2
1.2
iu/ml
158.5
167.6
—
8
42
(36031861) Influenza virus A and B and SARS-CoV-2 (COVID-19) and Respiratory syncytial virus RNA panel - Respiratory system specimen by NAA with probe detection
16
86
1.93
1.55
1.8
1.5
—
—
—
0
0
(3009508) Creatinine [Moles/volume] in Urine
67
520
1.42
1.54
3.0
2.9
mmol/l
7.4
7.7
0.15
62
436
(3017895) Helicobacter pylori Ab [Units/volume] in Serum
11
51
2.22
1.53
2.3
1.6
—
—
—
0
0
(3024891) Influenza virus A+B Ag [Presence] in Specimen
11
51
2.22
1.53
1.2
1.2
—
—
—
0
0
(3048821) Cortisol [Moles/volume] in Serum or Plasma --post 1 mg dexamethasone PO overnight
5
15
3.39
1.53
1.0
1.2
—
—
—
0
0
(3017143) Hepatitis C virus Ab [Presence] in Serum
29
188
1.63
1.53
1.6
1.6
—
—
—
0
0
(3021901) Oxygen saturation in Capillary blood
6
21
2.91
1.51
4.5
1.8
—
—
—
0
0
(3004383) Neutrophil cytoplasmic Ab.classic [Titer] in Serum by Immunofluorescence
9
37
2.49
1.50
1.1
1.1
—
—
—
0
0
(3001079) Blood group antibody screen [Presence] in Serum or Plasma
95
786
1.38
1.49
5.2
4.0
—
—
—
0
0
(3020630) Protein [Mass/volume] in Serum or Plasma
21
126
1.74
1.46
2.1
2.2
g/l
61.7
67.3
1.82
21
115
(3013527) Hepatitis B virus core IgM Ab [Presence] in Serum
7
28
2.55
1.46
1.1
1.3
—
—
—
0
0
(40764999) Glomerular filtration rate/1.73 sq M.predicted [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (CKD-EPI)
177
1631
1.53
1.46
20.4
12.3
ml/min/173m2
79.7
82.6
0.96
155
1326
(4024509)
5
16
3.17
1.44
1.8
1.1
—
—
—
0
0
(42868544) Hantavirus puumala IgM Ab [Presence] in Serum or Plasma by Immunofluorescence
6
22
2.78
1.44
1.2
1.2
—
—
—
0
0
(3021788) Differential panel - Synovial fluid
6
22
2.78
1.44
1.3
1.3
—
—
—
0
0
(46236098) ABO and Rh group [Type] in Blood by Confirmatory method
52
390
1.44
1.43
2.1
2.1
—
—
—
0
0
(3026008) Bacteria identified in Urine by Culture
62
485
1.39
1.34
5.7
3.0
—
—
—
0
0
(3014576) Chloride [Moles/volume] in Serum or Plasma
29
195
1.56
1.33
7.1
6.2
mmol/l
106.2
103.8
1.41
29
189
(3023024) Carbon dioxide [Partial pressure] in Capillary blood
14
77
1.88
1.29
9.4
2.8
kpa
5.2
5.0
0.40
14
71
(40762366) Oxygen capacity [Volume Fraction] in Arterial blood
14
77
1.88
1.29
35.8
15.2
—
—
—
0
0
(40758558) Short blood count panel - Blood
56
435
1.39
1.26
6.9
7.0
—
—
—
0
0
(3029879) Epithelial cells.squamous [#/volume] in Urine by Automated count
37
267
1.47
1.24
3.6
2.9
e6/l
3.5
2.6
0.24
19
148
(3044254) Respiratory syncytial virus RNA [Presence] in Specimen by NAA with probe detection
11
57
1.98
1.19
1.6
1.7
—
—
—
0
0
(3052851) Hemolysis interference index of Serum or Plasma
10
50
2.05
1.18
5.1
3.1
—
—
—
0
0
(3029937) Albumin [Presence] in Urine by Test strip
58
458
1.37
1.18
5.2
3.8
estimate
0.0
0.0
0.00
31
152
(3023419) Bacteria identified in Sputum by Culture
5
20
2.53
1.16
3.0
2.3
—
—
—
0
0
(40760888) Immunoglobulin light chains.free panel - Serum
5
20
2.53
1.16
3.6
4.3
—
—
—
0
0
(3013512) EKG study
59
469
1.36
1.15
4.7
3.6
—
—
—
0
0
(3020059) Calcium [Moles/volume] corrected for albumin in Serum or Plasma
42
316
1.41
1.13
4.7
2.8
mmol/l
2.4
2.4
1.06
37
280
(3013139) Helicobacter pylori Ag [Presence] in Stool
17
104
1.69
1.13
1.1
1.2
—
—
—
0
0
(3015235) Bicarbonate [Moles/volume] in Capillary blood
7
31
2.30
1.11
5.7
1.6
mmol/l
25.0
24.0
—
7
24
(3000991) Gas panel - Venous blood
20
129
1.61
1.10
10.3
7.6
—
—
—
0
0
(3036086) Jo-1 extractable nuclear Ab [Units/volume] in Serum by Immunoassay
7
32
2.23
1.09
1.1
1.3
—
—
—
0
0
(40768804) Tissue Pathology biopsy report
81
680
1.31
1.09
2.1
1.9
—
—
—
0
0
(3026493) Urate [Moles/volume] in Serum or Plasma
53
418
1.36
1.09
2.2
2.5
umol/l
362.8
4574.0
1.52
43
350
(3020460) C reactive protein [Mass/volume] in Serum or Plasma
185
1746
1.48
1.08
22.3
13.5
mg/l
21.2
22.4
0.21
164
1372
(3005322) IgE [Units/volume] in Serum or Plasma
15
91
1.70
1.03
1.3
1.3
u/ml
93.8
216.0
1.12
15
80
(3045783) Sodium and Potassium panel [Moles/volume] - Serum or Plasma
11
186
0.57
1.01
21.3
7.2
—
—
—
0
0
(3002434) Lupus erythematosus deoxynucleoproteins IgG Ab [Units/volume] in Serum by Immunoassay
9
49
1.87
1.00
1.3
2.1
—
—
—
0
0
(3005772) Bilirubin.conjugated [Moles/volume] in Serum or Plasma
29
209
1.45
0.99
2.8
2.6
umol/l
6.0
7.7
0.50
24
182
(3030366) Cystatin C [Mass/volume] in Serum or Plasma
9
50
1.83
0.98
12.8
2.2
mg/l
1.5
1.5
—
9
43
(3024135) Streptococcus.beta-hemolytic [Presence] in Throat by Organism specific culture
42
327
1.36
0.93
1.4
1.6
—
—
—
0
0
(3019800) Troponin T.cardiac [Mass/volume] in Serum or Plasma
76
644
1.28
0.93
5.4
3.4
ng/l
27.8
38.6
0.65
54
425
(3021337) Troponin I.cardiac [Mass/volume] in Serum or Plasma
41
321
1.34
0.88
4.1
3.5
ng/l
51.5
230.6
1.47
28
248
(3016502) Oxygen saturation in Arterial blood
22
155
1.47
0.85
27.4
10.5
%
96.6
96.2
0.23
22
149
(3002173) Hemoglobin [Mass/volume] in Arterial blood
21
147
1.48
0.84
28.9
11.0
g/l
116.1
122.3
0.95
21
142
(3047007) Chlamydophila sp Ab [Presence] in Serum
0
25
0.00
0.79
0.0
1.0
—
—
—
0
0
(1175715) Chlamydophila pneumoniae IgM Ab [Presence] in Serum by Immunoassay
0
26
0.00
0.79
0.0
1.1
—
—
—
0
0
(3007080) Epstein Barr virus nuclear IgG Ab [Units/volume] in Serum
5
24
2.11
0.75
1.6
1.3
u/ml
343.8
285.1
—
5
12
(3019284) Hepatitis B virus surface Ag [Presence] in Serum
30
230
1.35
0.75
1.9
1.6
—
—
—
0
0
(46235759) Influenza virus B RNA [Presence] in Nasopharynx by NAA with probe detection
10
60
1.70
0.73
1.8
1.7
—
—
—
0
0
(3022313) Gas panel - Capillary blood
9
56
1.63
0.73
11.1
3.1
—
—
—
0
0
(3028026) IgM [Mass/volume] in Serum or Plasma
16
109
1.51
0.73
1.5
1.5
g/l
1.2
1.4
0.35
16
100
(3007844) Epstein Barr virus capsid IgM Ab [Units/volume] in Serum by Immunoassay
5
25
2.02
0.73
1.6
1.2
—
—
—
0
0
(586526) SARS-CoV-2 (COVID-19) RNA [Presence] in Nasopharynx by NAA with probe detection
14
94
1.52
0.68
1.5
1.3
—
—
—
0
0
(3019832) Treponema pallidum Ab [Presence] in Serum
19
139
1.40
0.63
1.5
1.8
—
—
—
0
0
(46237023) Hepatitis B virus core and surface Ab and surface Ag panel - Serum
8
50
1.62
0.62
1.4
1.2
—
—
—
0
0
(3000494) Fungus identified in Specimen by Culture
28
221
1.31
0.59
2.3
1.4
—
—
—
0
0
(3029511) Human papilloma virus DNA [Presence] in Specimen by NAA with probe detection
8
53
1.53
0.59
1.3
1.5
—
—
—
0
0
(3018251) Fasting glucose [Moles/volume] in Serum or Plasma
176
1686
1.26
0.59
5.0
4.4
mmol/l
5.8
5.9
1.07
167
1555
(3050238) Crystals [Presence] in Synovial fluid by Light microscopy
6
35
1.73
0.58
1.0
1.3
—
—
—
0
0
(3002256) Pathology report gross observation
24
186
1.33
0.57
1.3
1.2
—
—
—
0
0
(40768443) Skin Pathology biopsy report
11
73
1.53
0.57
1.2
1.2
—
—
—
0
0
(3012544) pH of Venous blood
21
160
1.35
0.56
8.5
4.1
—
—
—
0
0
(3016417) Amylase.pancreatic [Enzymatic activity/volume] in Serum or Plasma
22
169
1.34
0.56
1.9
2.4
u/l
24.9
30.5
0.72
12
142
(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection
124
1153
1.18
0.55
3.2
3.2
—
—
—
0
0
(3002109) Cholesterol in LDL/Cholesterol in HDL [Mass Ratio] in Serum or Plasma
12
169
0.69
0.54
1.8
1.8
—
—
—
0
0
(3004588) Protein electrophoresis panel - Serum or Plasma
15
110
1.39
0.50
1.5
2.0
—
—
—
0
0
(3000330) Specific gravity of Urine by Test strip
13
93
1.42
0.49
5.1
3.5
—
—
—
0
0
(3048773) Triglyceride [Moles/volume] in Serum or Plasma --fasting
172
1653
1.22
0.49
4.5
3.9
mmol/l
1.4
1.3
1.42
164
1522
(1761482) Bacteria [#/volume] in Urine by Culture
7
46
1.54
0.49
7.3
5.0
—
—
—
0
0
(3006923) Alanine aminotransferase [Enzymatic activity/volume] in Serum or Plasma
191
1857
1.30
0.48
13.5
10.0
u/l
31.6
26.5
0.51
186
1802
(3001784) Prostate Specific Ag Free/Prostate specific Ag.total in Serum or Plasma
40
340
1.22
0.48
4.5
3.9
%
19.8
20.3
0.09
17
143
(3044491) Cholesterol non HDL [Mass/volume] in Serum or Plasma
8
120
0.65
0.47
1.8
1.4
—
—
—
0
0
(3047181) Lactate [Moles/volume] in Blood
7
49
1.44
0.46
67.3
15.3
mmol/l
1.1
1.2
—
7
42
(3016251) Hemoglobin.gastrointestinal [Presence] in Stool
12
86
1.42
0.45
3.0
2.2
—
—
—
0
0
(36660697) Celiac disease serology panel - Serum
19
148
1.31
0.45
1.2
1.2
—
—
—
0
0
(3011397) Hemoglobin [Presence] in Urine by Test strip
46
399
1.20
0.45
4.3
3.4
—
—
—
0
0
(3007461) Platelets [#/volume] in Blood
198
1937
1.36
0.44
32.3
19.4
e9/l
258.1
252.2
0.46
191
1898
(3001019) Free T4 and TSH panel - Serum or Plasma
12
87
1.40
0.43
1.4
1.8
—
—
—
0
0
(3026361) Erythrocytes [#/volume] in Blood
198
1938
1.35
0.42
32.1
19.4
e12/l
4.5
4.5
0.65
191
1890
(3010813) Leukocytes [#/volume] in Blood
198
1938
1.35
0.42
32.2
19.5
e9/l
6.8
6.6
1.01
191
1891
(3003740) Influenza virus B Ag [Presence] in Specimen
5
33
1.53
0.41
1.0
1.1
—
—
—
0
0
(3002523) Influenza virus A Ag [Presence] in Specimen
5
33
1.53
0.41
1.0
1.1
—
—
—
0
0
(3008832) Norclozapine [Moles/volume] in Serum or Plasma
0
15
0.00
0.41
0.0
12.2
—
782.1
—
0
15
(3000081) cloZAPine [Moles/volume] in Serum or Plasma
0
15
0.00
0.41
0.0
15.5
—
1251.0
—
0
15
(1617658) Protocol used for examination of sentinel lymph nodes
0
16
0.00
0.41
0.0
1.0
—
—
—
0
0
(3004915) Chlamydophila pneumoniae IgA Ab [Units/volume] in Serum
0
16
0.00
0.41
0.0
1.1
—
—
—
0
0
(4146454)
0
16
0.00
0.41
0.0
2.9
—
—
—
0
0
(1002224) Polysomnography panel
11
80
1.40
0.39
1.0
1.1
—
—
—
0
0
(3026910) Gamma glutamyl transferase [Enzymatic activity/volume] in Serum or Plasma
128
1215
1.14
0.37
3.9
2.9
u/l
49.7
45.9
0.24
119
1146
(43054914) Glucose tolerance 2 hours panel - Serum or Plasma
20
163
1.25
0.35
1.8
1.7
—
—
—
0
0
(3046870) Tissue transglutaminase IgG Ab [Units/volume] in Serum
10
73
1.39
0.35
1.1
1.0
—
—
—
0
0
(3011288) Drugs identified in Urine by Screen method
6
46
1.31
0.33
3.0
1.5
—
—
—
0
0
(3009542) Hematocrit [Volume Fraction] of Blood
155
1601
0.88
0.31
23.1
14.5
%
38.5
40.3
1.27
115
1202
(3003327) Ova and parasites identified in Stool by Light microscopy
7
54
1.31
0.30
1.7
1.4
—
—
—
0
0
(3001308) Cholesterol in LDL [Moles/volume] in Serum or Plasma
180
1756
1.17
0.30
5.3
4.8
mmol/l
2.7
2.8
0.93
174
1627
(1761868) Lipid panel - Serum or Plasma
71
657
1.12
0.30
3.7
2.7
—
—
—
0
0
(3019150) Specific gravity of Urine by Refractometry
35
395
0.86
0.30
5.5
3.4
kg/l
1.0
1.0
—
6
52
(3018006) Microscopic observation [Identifier] in Cervix by Cyto stain.thin prep
32
282
1.16
0.27
1.3
1.4
—
—
—
0
0
(3000764) Benzodiazepines [Presence] in Urine
8
65
1.24
0.27
2.4
1.3
—
—
—
0
0
(3027944) Amphetamines [Presence] in Urine
8
66
1.22
0.27
2.4
1.3
—
—
—
0
0
(3028300) Cannabinoids [Presence] in Urine
8
66
1.22
0.27
2.4
1.3
—
—
—
0
0
(3027008) Opiates [Presence] in Urine
8
66
1.22
0.27
2.4
1.3
—
—
—
0
0
(3033319) Streptococcus pyogenes Ag [Presence] in Throat
21
179
1.19
0.26
1.2
1.5
—
—
—
0
0
(3011371) Neisseria gonorrhoeae DNA [Presence] in Specimen by NAA with probe detection
9
74
1.23
0.25
1.2
2.1
—
—
—
0
0
(3045414) Leukocytes [Presence] in Urine
10
78
1.30
0.24
1.7
2.0
—
—
—
0
0
(3024403) Complement+Immunoglobulin [Units/volume] in Red Blood Cells
5
38
1.32
0.23
1.0
2.1
—
—
—
0
0
(3050129) First trimester maternal screen panel - Serum or Plasma
5
38
1.32
0.23
2.2
1.4
—
—
—
0
0
(3024928) Oxygen saturation in Venous blood
5
39
1.29
0.23
12.8
3.1
—
—
—
0
0
(44816752) ERBB2 gene copy number/nucleus in Tissue by FISH
0
11
0.00
0.21
0.0
1.1
—
—
—
0
0
(3042206) Streptococcus agalactiae Ag [Presence] in Vaginal fluid
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
(3035320) C reactive protein [Mass/volume] in Body fluid
0
10
0.00
0.21
0.0
3.2
—
—
—
0
0
(36305771) Cryptosporidium sp DNA [Presence] in Stool by NAA with probe detection
0
12
0.00
0.21
0.0
1.2
—
—
—
0
0
(37020937) Giardia lamblia DNA [Presence] in Stool by NAA with probe detection
0
12
0.00
0.21
0.0
1.2
—
—
—
0
0
(3044242) Glucose [Moles/volume] in Arterial blood
0
12
0.00
0.21
0.0
7.2
—
—
—
0
0
(3049506) Microalbumin [Mass/time] in Urine collected for unspecified duration
0
13
0.00
0.21
0.0
1.6
—
—
—
0
0
(3053028) Streptococcus sp identified in Specimen by Organism specific culture
0
13
0.00
0.21
0.0
1.0
—
—
—
0
0
(3025018) Bordetella pertussis Ab [Titer] in Serum
0
13
0.00
0.21
0.0
1.3
—
—
—
0
0
(3003510) Neisseria gonorrhoeae DNA [Presence] in Urine by NAA with probe detection
14
165
0.84
0.20
1.9
2.0
—
—
—
0
0
(3005013) Prostate Specific Ag Free [Mass/volume] in Serum or Plasma
28
252
1.13
0.19
3.1
2.6
ug/l
0.9
0.6
0.49
19
149
(3046279) Procalcitonin [Mass/volume] in Serum or Plasma
7
58
1.21
0.18
4.4
1.6
ug/l
1.6
5.9
—
7
50
(3025839) Triglyceride [Moles/volume] in Serum or Plasma
52
487
1.09
0.17
1.7
1.7
mmol/l
1.4
1.4
0.05
44
424
(42529406) Shigella sp [Presence] in Stool by Culture
7
62
1.13
0.17
1.3
1.1
—
—
—
0
0
(3006418) Campylobacter sp identified in Tissue by Organism specific culture
7
62
1.13
0.17
1.3
1.1
—
—
—
0
0
(3014765) Yersinia sp identified in Stool by Organism specific culture
7
62
1.13
0.17
1.3
1.1
—
—
—
0
0
(40761511) CBC panel - Blood by Automated count
185
1823
1.12
0.17
23.4
12.2
—
—
—
0
0
(3043723) Beta 1 globulin [Mass/volume] in Serum or Plasma by Electrophoresis
5
70
0.71
0.17
1.2
1.8
—
—
—
0
0
(3024950) Chlamydia trachomatis DNA [Presence] in Urine by NAA with probe detection
16
182
0.87
0.16
1.9
2.1
—
—
—
0
0
(3019900) Cholesterol [Moles/volume] in Serum or Plasma
175
1723
1.09
0.15
5.0
4.3
mmol/l
4.6
4.7
0.90
168
1607
(3019060) Gas panel - Arterial blood
12
103
1.18
0.14
40.6
8.6
—
—
—
0
0
(3004716) Salmonella sp identified in Stool by Organism specific culture
9
107
0.83
0.13
1.8
1.3
—
—
—
0
0
(3041942) Cyclic citrullinated peptide Ab [Units/volume] in Serum
32
297
1.09
0.13
1.3
1.2
u/ml
1.1
8.0
2.60
12
129
(3000492) Spirometry study
15
169
0.88
0.13
1.5
1.5
—
—
—
0
0
(4010399)
11
125
0.87
0.10
1.5
1.4
—
—
—
0
0
(3003785) Carcinoembryonic Ag [Mass/volume] in Serum or Plasma
19
174
1.10
0.10
4.6
4.1
ug/l
232.1
8.1
0.46
14
142
(3014051) Protein [Presence] in Urine by Test strip
5
48
1.04
0.09
2.2
2.3
—
—
—
0
0
(40768793) Breast Pathology biopsy report
5
48
1.04
0.09
1.4
1.2
—
—
—
0
0
(3022217) INR in Platelet poor plasma by Coagulation assay
19
206
0.91
0.09
10.9
23.5
inr
1.0
1.4
—
5
28
(1001926) Buprenorphine [Presence] in Urine by Screen method
6
54
1.11
0.09
2.8
1.2
—
—
—
0
0
(3023602) Cholesterol in HDL [Moles/volume] in Serum or Plasma
173
1711
1.06
0.09
4.8
4.3
mmol/l
1.4
1.5
2.53
168
1586
(36032419) SARS-CoV-2 (COVID-19) Ag [Presence] in Upper respiratory specimen by Immunoassay
6
56
1.07
0.08
2.2
1.8
—
—
—
0
0
(4034850)
5
65
0.76
0.08
3.2
12.8
—
—
—
0
0
(3023081) Carboxyhemoglobin/Hemoglobin.total in Blood
7
64
1.10
0.08
67.0
12.6
%
1.3
1.6
—
7
59
(3020891) Body temperature
7
65
1.08
0.08
4.9
3.6
—
—
—
0
0
(40761535) Cells panel - Urine sediment
12
130
0.92
0.04
4.8
3.2
—
—
—
0
0
(3019225) pH of Specimen
12
129
0.93
0.03
5.8
3.9
—
—
—
0
0
(3006093) Chlamydia trachomatis DNA [Presence] in Specimen by NAA with probe detection
10
92
1.09
0.03
1.3
2.1
—
—
—
0
0
(3022621) pH of Urine by Test strip
13
126
1.03
0.00
3.2
3.0
—
—
—
0
0
(3003694) ABO and Rh group [Type] in Blood
45
445
1.01
0.00
1.5
1.4
—
—
—
0
0
(3028433) Virus identified in Specimen by Culture
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
(3043410) Blood group antigens tested for on Red Blood Cells
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
(3021584) Pregnancy associated plasma protein A [Units/volume] in Serum or Plasma
5
57
0.87
0.00
1.8
1.6
—
—
—
0
0
(3013293) Extractable nuclear Ab [Presence] in Serum
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
(3004446) Plasmodium sp identified in Blood by Light microscopy
0
5
0.00
0.00
0.0
3.0
—
—
—
0
0
(3013637) Mi-2 Ab [Presence] in Serum
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(40765096) Chromosome analysis panel by Banding
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(42529598) SUMO-activating enzyme subunit 1 Ab [Presence] in Serum by Line blot
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3037692) Legionella sp identified in Specimen by Organism specific culture
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
(3052592) Norovirus Ag [Presence] in Stool
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
(42529582) MDA5 Ab [Presence] in Serum by Line blot
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3044007) Cell count panel - Peritoneal fluid
0
5
0.00
0.00
0.0
1.8
—
—
—
0
0
(42528593) TIF1-gamma Ab [Presence] in Serum by Line blot
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3006462) Nitrate [Presence] in Urine
0
8
0.00
0.00
0.0
5.3
—
—
—
0
0
(40758897) Direct antiglobulin test.IgG specific reagent [Presence] on Red Blood Cells
0
8
0.00
0.00
0.0
3.0
—
—
—
0
0
(3028009) Chlamydia trachomatis IgG Ab [Units/volume] in Serum
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(21493195) Respiratory pathogens DNA and RNA tested for in Respiratory system specimen by NAA with probe detection
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(40758895) Direct antiglobulin test.complement C3d specific reagent [Presence] on Red Blood Cells
0
8
0.00
0.00
0.0
3.0
—
—
—
0
0
(3035457) Cefaclor IgE Ab [Units/volume] in Serum
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3024889) Methemoglobin/Hemoglobin.total in Venous blood
8
87
0.92
0.00
3.4
2.3
%
0.6
0.7
—
8
87
(3010521) Mycoplasma pneumoniae IgM Ab [Presence] in Serum by Immunoassay
5
50
1.00
0.00
1.8
1.1
—
—
—
0
0
(3008898) HLA-B27 [Presence]
7
75
0.93
0.00
1.0
1.1
—
—
—
0
0
(3000213) Normetanephrine [Moles/time] in 24 hour Urine
0
6
0.00
0.00
0.0
1.3
—
1.7
—
0
6
(3034603) RHD gene allele [Genotype] in Blood or Tissue by Molecular genetics method Nominal
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
(3029023) Hepatitis E virus IgG Ab [Presence] in Serum by Immunoassay
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
(3002619) Bacteria identified in Specimen by Culture
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
(3016879) Cocaine [Presence] in Urine
6
63
0.95
0.00
2.8
1.3
—
—
—
0
0
(3043409) Potassium [Moles/volume] in Arterial blood
5
53
0.94
0.00
3.2
3.5
mmol/l
3.6
3.8
—
5
48
(3002222) Hepatitis E virus IgM Ab [Presence] in Serum
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
(3006922) Hepatitis E virus Ab [Presence] in Serum
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
(46236952) Glomerular filtration rate/1.73 sq M.predicted [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (MDRD)
14
140
1.00
0.00
2.6
2.7
ml/min/173m2
56.0
65.5
—
6
56
(43534045) MCM6 gene c.-13910C>T and -13915T>G [Identifier] in Blood or Tissue by Molecular genetics method Nominal
9
90
1.00
0.00
1.0
1.0
—
—
—
0
0
(3021197) Magnesium Ionized [Moles/volume] in Serum or Plasma
0
6
0.00
0.00
0.0
1.7
—
—
—
0
0
(3048929) Epstein Barr virus Ab [Presence] in Serum
5
52
0.96
0.00
2.0
1.3
—
—
—
0
0
(3051593) INR in Capillary blood by Coagulation assay
0
7
0.00
0.00
0.0
9.4
—
—
—
0
0
(3044936) Clostridioides difficile toxin A+B [Presence] in Stool by Immunoassay
0
7
0.00
0.00
0.0
1.4
—
—
—
0
0
(3027231) Wheat IgE Ab [Units/volume] in Serum
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
(3030981) Hyaline casts [#/volume] in Urine by Automated count
9
91
0.99
0.00
4.6
2.5
e6/l
0.1
0.1
—
9
85
(3035933) Granulocytes/100 leukocytes in Blood
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
(3010517) Carboxyhemoglobin/Hemoglobin.total in Venous blood
9
90
1.00
0.00
4.3
2.3
%
1.6
1.3
—
9
90
(3028334) Neisseria gonorrhoeae [Presence] in Specimen by Organism specific culture
0
6
0.00
0.00
0.0
1.8
—
—
—
0
0
(3013566) Clostridioides difficile [Presence] in Stool by Organism specific culture
0
6
0.00
0.00
0.0
1.3
—
—
—
0
0
(3037556) Urate [Mass/volume] in Serum or Plasma
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint E4_PITUDISNAS and mortality.

Females

Parameter HR [95% CI] p-value
E4_PITUDISNAS 2.384 [1.81, 3.14] < 0.001
Birth year 0.992 [0.98, 1.0] 0.063

During the follow-up period (1.1.1998 — 31.12.2019), 84 out of 396 females with E4_PITUDISNAS died.

Males

Parameter HR [95% CI] p-value
E4_PITUDISNAS 1.387 [0.99, 1.95] 0.06
Birth year 0.989 [0.98, 1.0] 0.015

During the follow-up period (1.1.1998 — 31.12.2019), 55 out of 288 males with E4_PITUDISNAS died.

Mortality risk

Mortality risk for people of age

years, who have E4_PITUDISNAS.

N-year risk Females Males
1 0.202% 0.217%
5 1.248% 1.664%
10 3.13% 4.363%
15 5.77% 8.112%
20 10.357% 13.946%

Relationships between endpoints

Index endpoint: E4_PITUDISNAS – Disorders of pituitary gland, other and/or unspecified

GWS hits: 1

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
loading spinner Loading data