muscular disease: Acquired, familial, and congenital disorders of skeletal muscle and smooth muscle.
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
519972 |
1. Apply sex-specific ruleNone |
519972 |
2. Check conditionsNone |
519972 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
389 |
4. Check minimum number of eventsNone |
389 |
5. Include endpointsNone |
389 |
6. Filter based on genotype QC (FinnGen only) |
380 |
Control definitions (FinnGen only)
- Control exclude
- M13_SOFTTISSUE
Extra metadata
- Level in the ICD hierarchy
- 4
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- M79
- Name in latin
- Hypertrophia corporis adiposi infrapatellaris
Similar endpoints
↥List of similar endpoints to
Hypertrophy of (infrapatellar) fat pad
based on the number of shared cases.
Similar with more cases:
- Other soft tissue disorders, not elsewhere classified
- Soft tissue disorders
- Diseases of the musculoskeletal system and connective tissue
- Any event in hilmo or specialist outpatient
- Any prescribed medicine buy
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 2650 | 1415 | 1223 |
| Only index persons | 2524 | 1364 | 1160 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.04 | 0.04 | 0.03 |
| Only index persons | 0.05 | 0.05 | 0.04 |
| Median age at first event (years) | |||
| Whole population | 38.04 | 39.91 | 35.86 |
| Only index persons | 37.48 | 39.43 | 35.19 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 380 | 229 | 151 |
| Unadjusted period prevalence (%) | 0.08 | 0.08 | 0.07 |
| Median age at first event (years) | 37.84 | 36.24 | 40.27 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
No data
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 389
- Matched controls
- 3890
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
M79.4
ICD-10 Finland
Hypertrophy of (infrapatellar) fat pad
+∞
307.7
269
*
NGF00
NOMESCO Finland
Excision of plica of synovy of knee
64.8
139.2
78
15
7293A
ICD-9 Finland
Other disorders of soft tissues, Panniculitis, unspecified[LIPOSYNOVITIS INFRAPATELLARIS (MORBUS HOFFA)]
+∞
134.4
121
*
NGF25
NOMESCO Finland
Operation for osteochondritis of knee, arthroscopic
17.2
113.0
104
81
1225
FHL
Arthroscopy and other therapeutic procedure
30.3
71.0
48
18
M23.8
ICD-10 Finland
Other internal derangements of knee
15.9
67.1
61
45
NGF35
NOMESCO Finland
Plastic operation of joint cartilage of knee
14.8
56.5
53
41
M23.2
ICD-10 Finland
Derangement of meniscus due to old tear or injury
6.8
55.7
105
201
NGD05
NOMESCO Finland
Partial excision of meniscus of knee, arthroscopic
5.6
40.7
90
197
1220
FHL
Arthroscopy
10.9
39.9
45
46
M25.5
ICD-10 Finland
Pain in joint
3.9
38.3
178
688
M79.6
ICD-10 Finland
Pain in limb
3.8
37.2
190
780
M75.1
ICD-10 Finland
Rotator cuff syndrome
4.5
36.2
110
312
ZXE00
NOMESCO Finland
One hour or less
3.4
31.2
205
962
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
3.3
29.4
219
1096
N03AX16
ATC
[U] pregabalin
3.8
28.9
113
379
N02AX02
ATC
tramadol; systemic, rectal
3.2
28.5
191
894
M01AH05
ATC
etoricoxib; oral
3.6
28.4
289
1728
Z96.6
ICD-10 Finland
Presence of orthopaedic joint implants
9.1
28.3
36
43
M17.1
ICD-10 Finland
Other primary gonarthrosis
3.9
28.1
104
335
ZXM10
NOMESCO Finland
Intraoperative use of conventional X-ray imaging
5.9
26.4
51
97
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
3.3
26.0
133
526
1221
FHL
Arthroscopy and meniscus surgery
11.1
25.6
28
27
M22.4
ICD-10 Finland
Chondromalacia patellae
9.5
25.4
31
35
S83.2
ICD-10 Finland
Tear of meniscus, current
5.3
24.4
53
112
1222
FHL
Arthroscopy and synovial surgery
36.0
23.7
30
9
NGA30
NOMESCO Finland
Exploration of knee joint, arthroscopic
6.5
22.6
39
66
NGF15
NOMESCO Finland
Total synovectomy of knee, arthroscopic
37.6
22.4
28
8
SPAT1153
SPAT
Removal of sutures
3.0
22.3
146
656
SPAT1249
SPAT
Treatment-related counselling outside office
2.8
21.8
187
967
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
4.5
20.9
55
136
N06AX21
ATC
duloxetine; oral
4.1
20.9
65
183
WX320
NOMESCO Finland
Spinalanesthesy
3.0
20.6
115
471
M01AB05
ATC
diclofenac; systemic, rectal
3.0
20.2
291
1934
M79.0
ICD-10 Finland
Rheumatism, unspecified
60.9
20.1
23
*
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
3.7
20.0
72
224
R01AD12
ATC
fluticasone furoate; nasal
2.7
19.1
168
867
WX723
NOMESCO Finland
CPAP therapy
5.6
19.0
38
74
M23.9
ICD-10 Finland
Internal derangement of knee, unspecified
4.1
18.8
57
157
NK4XE
NOMESCO Finland
Joint ultrasound examination not elsewhere classified
5.0
18.2
41
89
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
2.7
18.0
127
584
ZXE10
NOMESCO Finland
More than one and less than three hours
2.6
17.5
162
849
L08
ICPC
Shoulder symptom/complaint
3.1
17.3
89
344
N03AX12
ATC
[U] gabapentin; oral
3.4
17.3
71
240
NA3BG
NOMESCO Finland
Lumbar spine MRI examination with high intensity magnet
4.3
17.2
48
124
SPAT1260
SPAT
Consultation of another employee
3.1
17.1
88
340
NBG15
NOMESCO Finland
Acromioplastia, arthroscopic
20.5
17.1
25
13
M02AA07
ATC
piroxicam; topical
2.6
16.8
144
725
M47.82
ICD-10 Finland
Other spondylosis, cervical region
7.4
16.7
25
36
M70.6
ICD-10 Finland
Trochanteric bursitis
3.9
16.5
53
152
M75.0
ICD-10 Finland
Adhesive capsulitis of shoulder
6.2
16.4
29
50
M75.4
ICD-10 Finland
Impingement syndrome of shoulder
14.4
16.2
27
20
A02BC02
ATC
pantoprazole; systemic
2.5
15.8
270
1840
SPAT1312
SPAT
General health counselling
2.5
15.7
143
737
GD1AA
NOMESCO Finland
Thorax X-ray examination
2.4
15.3
178
1022
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
3.8
15.1
50
146
M54.5
ICD-10 Finland
Low back pain
2.4
14.6
151
820
LX1AE
NOMESCO Finland
Gynecological ultrasound examination as part of clinical examination
3.2
14.4
63
220
9254
FHL
Arthrotomy (includes biopsy, revision, loose removal, fixation, and similar procedures)
28.4
14.4
19
7
M51.1
ICD-10 Finland
Lumbar and other intervertebral disc disorders with radiculopathy
3.1
14.4
69
255
M01AC06
ATC
meloxicam; systemic, rectal
2.4
14.4
150
816
H02AB06
ATC
prednisolone; systemic
2.3
14.4
190
1143
N02BF01
ATC
gabapentin; oral
4.3
14.3
39
99
NA1BG
NOMESCO Finland
Cervical spine MRI examination with high intensity magnet
5.3
14.1
29
58
M54.4
ICD-10 Finland
Lumbago with sciatica
2.8
14.0
80
325
TDW99
NOMESCO Finland
Other minor procedure in surgery of ear, nose and larynx
6.3
14.0
24
40
N02AJ06
ATC
codeine and paracetamol; systemic
2.3
14.0
177
1042
M79.7
ICD-10 Finland
Fibromyalgia
18.4
14.0
21
12
L15
ICPC
Knee symptom/complaint
2.6
13.9
102
471
XX3DW
NOMESCO Finland
Time consuming IT work
3.2
13.8
60
209
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
2.3
13.7
151
837
M51.3
ICD-10 Finland
Other specified intervertebral disc degeneration
4.2
13.6
38
98
SPAT1211
SPAT
Application of soft bandage
3.8
13.5
43
122
7170A
ICD-9 Finland
Internal derangement of knee, Old bucket handle tear of medial meniscus
12.8
13.3
23
19
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
3.8
13.2
42
119
M03BX02
ATC
tizanidine; oral
2.3
13.0
264
1866
M01AX05
ATC
glucosamine; oral
2.8
12.9
74
301
SPAT1377
SPAT
Polysomnography
5.4
12.9
26
51
X59
ICD-10 Finland
Exposure to unspecified factor
2.7
12.8
84
366
M01AX17
ATC
nimesulide; oral
2.6
12.6
91
415
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
2.4
12.5
111
557
A02BC01
ATC
omeprazole; systemic
2.4
12.4
113
574
M19.0
ICD-10 Finland
Primary arthrosis of other joints
3.9
12.3
37
101
WX780
NOMESCO Finland
Remote monitoring CPAP
4.2
12.0
33
84
SPAT1301
SPAT
No procedures
2.3
12.0
125
671
N06AA09
ATC
amitriptyline; systemic
3.6
11.9
41
123
WX402
NOMESCO Finland
General anaesthesia
2.4
11.7
99
485
NG1AA
NOMESCO Finland
Knee X-ray examination without contrast
3.3
11.6
47
156
M79.1
ICD-10 Finland
Myalgia
2.9
11.6
59
224
Z01.9
ICD-10 Finland
Special examination, unspecified
3.8
11.6
37
105
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
2.5
11.4
81
365
UDC00
NOMESCO Finland
Ear microscopy
3.6
11.4
39
116
SPAT1263
SPAT
Sampling
2.1
11.2
170
1051
M09AX01
ATC
hyaluronic acid; parenteral
5.5
11.2
22
42
G56.0
ICD-10 Finland
Carpal tunnel syndrome
3.0
11.2
55
205
NB1AA
NOMESCO Finland
Shoulder X-ray examination without contrast
4.6
11.2
27
62
J01FA09
ATC
clarithromycin; systemic
2.2
11.1
136
776
M01AE03
ATC
ketoprofen; systemic, rectal
2.1
10.8
140
815
M54.1
ICD-10 Finland
Radiculopathy
5.0
10.6
23
48
R51.80
ICD-10 Finland
Headache
2.6
10.6
68
292
M03BC51
ATC
orphenadrine, combinations; systemic
2.2
10.5
118
649
J01.0
ICD-10 Finland
Acute maxillary sinusitis
2.2
10.4
107
566
M17.0
ICD-10 Finland
Primary gonarthrosis, bilateral
2.8
10.4
55
213
G54.0
ICD-10 Finland
Brachial plexus disorders
7.8
10.3
23
31
NH3EA
NOMESCO Finland
Feet X-ray examination with load
11.7
10.2
18
16
M01AE02
ATC
naproxen; oral, rectal
2.0
10.2
230
1626
J01FA10
ATC
azithromycin; systemic
2.0
10.1
243
1754
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
3.3
10.1
39
126
G47.3
ICD-10 Finland
Sleep apnoea
2.2
10.0
100
522
L13
ICPC
Hip symptom/complaint
2.6
10.0
65
280
M01AH02
ATC
rofecoxib; oral
3.0
10.0
46
165
R06AE07
ATC
cetirizine; oral
2.0
9.9
180
1176
D82
ICPC
Teeth/gum disease
2.0
9.7
165
1050
WZC00
NOMESCO Finland
Treatment plan or consultation
2.0
9.7
145
882
UDQ12
NOMESCO Finland
Flexible laryngoscopy
3.7
9.7
32
93
R01AD08
ATC
fluticasone; nasal
2.1
9.7
127
737
R52.2
ICD-10 Finland
Other chronic pain
5.0
9.6
21
44
SPAT1281
SPAT
Other administrative function
3.2
9.6
40
135
M02AA10
ATC
ketoprofen; topical
2.5
9.6
64
279
ND2AA
NOMESCO Finland
Hand and fingers X-ray examination
3.1
9.6
41
141
NG1BG
NOMESCO Finland
Knee and lower leg MRI examination with high intensity magnet
4.5
9.5
23
53
NDM40
NOMESCO Finland
Discission of sheath of tendon of wrist or hand
+∞
9.4
9
*
M47.2
ICD-10 Finland
Other spondylosis with radiculopathy
4.2
9.4
25
62
M67.4
ICD-10 Finland
Ganglion
4.3
9.3
24
58
N02BE01
ATC
paracetamol; systemic, rectal
2.7
9.2
345
2895
R07.4
ICD-10 Finland
Chest pain, unspecified
2.2
9.2
100
539
M01AB08
ATC
etodolac; oral
3.4
9.0
33
103
FP4B5
NOMESCO Finland
ECG, prolonged recording (24 h)
12.9
8.9
15
12
M01AH01
ATC
celecoxib; oral
2.4
8.9
66
302
SCA02
NOMESCO Finland
Preventive oral health care
2.6
8.8
53
219
SPAT1253
SPAT
Initiation, adjustment, discontinuation or repetition of medication
2.0
8.8
117
678
J01AA02
ATC
doxycycline; systemic
2.1
8.7
303
2427
L90
ICPC
Osteoarthrosis of knee
3.6
8.7
29
85
R10.1
ICD-10 Finland
Pain localized to upper abdomen
2.3
8.6
71
341
L28
ICPC
Limited function/disability (L)
2.6
8.6
51
210
TNX10
NOMESCO Finland
Arthrocentesis, unspecified region, unspecified region
3.7
8.6
27
76
XF404
NOMESCO Finland
Ambulatory ECG
3.0
8.6
39
139
WX110
NOMESCO Finland
Infiltration anesthesia
2.0
8.5
283
2220
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
1.9
8.5
207
1466
WZC20
NOMESCO Finland
Multidisciplinary treatment meeting
3.2
8.5
34
112
WX204
NOMESCO Finland
Axillary plexus blockaced
5.1
8.4
18
37
R53
ICD-10 Finland
Malaise and fatigue
2.1
8.4
91
488
HAHOM, ,
NOMESCO Finland
8.8
8.4
17
20
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
2.1
8.4
89
474
M54
ICD-10 Finland
Dorsalgia
2.5
8.4
55
238
S46.0
ICD-10 Finland
Injury of muscle(s) and tendon(s) of the rotator cuff of shoulder
3.4
8.3
30
93
I20.99
ICD-10 Finland
Angina pectoris, unspecified
3.9
8.2
24
64
M77.1
ICD-10 Finland
Lateral epicondylitis
3.3
8.1
31
99
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
1.9
8.1
157
1029
M79.2
ICD-10 Finland
Neuralgia and neuritis, unspecified
12.0
8.1
14
12
R06.0
ICD-10 Finland
Dyspnoea
2.1
8.1
95
524
XX9TE
NOMESCO Finland
Compementary ultrasound examination
34.1
8.1
10
*
1223
FHL
Arthroscopy and articular cartilage surgery
13.4
7.9
13
10
D07AC01
ATC
betamethasone; topical
1.9
7.9
139
883
L03
ICPC
Low back symptom/complaint
2.0
7.8
101
578
SPAT1097
SPAT
Recording of ECG
2.4
7.8
55
246
SPAT1310
SPAT
Counselling related to known health issue
1.9
7.7
119
724
M54.9
ICD-10 Finland
Dorsalgia, unspecified
2.5
7.7
49
209
NA3CG
NOMESCO Finland
Lumbar spine extensive MRI examination with high intensity magnet
4.6
7.5
18
41
L01
ICPC
Neck symptom/complaint
2.3
7.5
61
291
R03DC03
ATC
montelukast; oral
2.2
7.4
70
354
L04AB01
ATC
etanercept; parenteral
13.7
7.4
12
9
SPAT1156
SPAT
Guidance concerning treatment of rash and skin
2.5
7.4
48
206
S83.6
ICD-10 Finland
Sprain and strain of other and unspecified parts of knee
3.4
7.4
27
84
H92.0
ICD-10 Finland
Otalgia
3.2
7.4
30
100
B01AB05
ATC
enoxaparin; parenteral
1.9
7.3
111
668
A02BA02
ATC
ranitidine; systemic
2.2
7.3
68
342
ZXC50
NOMESCO Finland
Cryotherapy
6.0
7.3
19
33
7261X
ICD-9 Finland
Peripheral enthesopathies and allied syndromes, Rotator cuff syndrome of shoulder and allied disorders[MUU TAI TARKEMMIN MÄÄRITTELEM KIERTÄJÄKALVOSINSDR]
+∞
7.3
7
*
NH3AA
NOMESCO Finland
Foot and toes X-ray examination
3.0
7.3
33
117
R03AC02
ATC
salbutamol; inhalant
1.8
7.3
214
1578
SPAT1295
SPAT
Other function in accordance with physical therapy nomenclature
3.8
7.3
22
60
G56.2
ICD-10 Finland
Lesion of ulnar nerve
4.4
7.3
18
42
J01DB01
ATC
cefalexin; oral
2.1
7.3
320
2680
NGB20
NOMESCO Finland
Primary total prosthetic replacement of knee joint without patellar part
2.8
7.2
37
141
JN3AD
NOMESCO Finland
Abdominal CT examination
2.5
7.2
46
196
A06AC01
ATC
ispaghula (psylla seeds); oral
2.0
7.2
93
530
UJF32
NOMESCO Finland
Coloscopy
2.0
7.2
90
507
H02BX01
ATC
methylprednisolone, combinations; systemic
4.2
7.2
19
47
SPAT1256
SPAT
Intramuscular and subcutaneous injection
1.8
7.1
151
1011
M13.9
ICD-10 Finland
Arthritis, unspecified
3.1
7.1
29
97
F45.4
ICD-10 Finland
Persistent somatoform pain disorder
10.3
7.1
13
13
NG1CG
NOMESCO Finland
Knee and lower leg extensive MRI examination with high intensity magnet
7.2
7.1
16
23
N05BA01
ATC
diazepam; systemic, rectal
2.3
7.0
55
257
202
Kela drug reimbursment
Connective tissue diseases, rheumatoid arthritis and comparable disease
2.6
7.0
42
173
M53.1
ICD-10 Finland
Cervicobrachial syndrome
2.4
7.0
48
212
A02BC05
ATC
esomeprazole; systemic
1.8
6.9
145
965
GD1DD
NOMESCO Finland
High resolution CT examination of lungs
3.4
6.8
24
73
NGF20
NOMESCO Finland
Operation for osteochondritis of knee, open
40.8
6.8
8
*
NBG00
NOMESCO Finland
Plastic operation on acromioclavicular joint
17.1
6.8
10
6
9242
FHL
Other reconstruction or plastic surgery of shoulder joint (including ac joint)
23.0
6.7
9
*
S89.9
ICD-10 Finland
Unspecified injury of lower leg
4.1
6.7
18
45
M23
ICD-10 Finland
Internal derangement of knee
5.7
6.7
18
33
WZB00
NOMESCO Finland
Telephone prescription or other care instructions
1.8
6.7
119
752
L01BA01
ATC
methotrexate; systemic
6.1
6.7
17
29
NB1BG
NOMESCO Finland
Shoulder and humerus MRI examination with high intensity magnet
12.5
6.6
11
9
NA1EA
NOMESCO Finland
Cervical spine X-ray examination with flexion
12.5
6.6
11
9
ZXD00
NOMESCO Finland
Emergency procedure
4.3
6.6
17
41
SCA03
NOMESCO Finland
Preventive oral health care, extensive
3.2
6.6
26
85
M48.0
ICD-10 Finland
Spinal stenosis
2.7
6.6
37
148
NG1DA
NOMESCO Finland
X-ray of knees
10.3
6.6
12
12
AA3AI
NOMESCO Finland
Cone beam CT of facial bones
10.3
6.6
12
12
M16.1
ICD-10 Finland
Other primary coxarthrosis
2.7
6.6
35
136
WX408
NOMESCO Finland
General anesthesy, balanced
1.9
6.5
96
570
Y88.3
ICD-10 Finland
Sequelae of surgical and medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
5.9
6.5
17
30
ACC51
NOMESCO Finland
Release of median nerve
3.1
6.5
27
91
P01BA02
ATC
hydroxychloroquine; oral
2.9
6.5
30
108
L04AX03
ATC
methotrexate; systemic
2.6
6.4
38
156
R03BA05
ATC
fluticasone; inhalant
2.0
6.4
72
389
M54.2
ICD-10 Finland
Cervicalgia
2.7
6.4
35
138
N05BA04
ATC
oxazepam; oral
1.9
6.4
97
582
FN1BC
NOMESCO Finland
Extensive angiography of hear and/or coronary arteries
4.0
6.3
18
47
TNX10, ,
SPAT
18.4
6.3
9
5
XA402
NOMESCO Finland
ENMG
7.2
6.3
14
20
7290A
ICD-9 Finland
Other disorders of soft tissues, Rheumatism, unspecified and fibrositis
+∞
6.3
6
*
L12
ICPC
Hand/finger symptom/complaint
2.2
6.3
59
298
ABC30
NOMESCO Finland
Decompression of cervical nerve roots
27.1
6.2
8
*
R05
ICPC
Cough
1.9
6.2
94
562
N05CF01
ATC
zopiclone; oral
1.8
6.2
112
709
R42
ICD-10 Finland
Dizziness and giddiness
2.0
6.2
75
417
S18
ICPC
Laceration/cut
1.7
6.1
155
1082
T84.0
ICD-10 Finland
Mechanical complication of internal joint prosthesis
6.9
6.1
14
21
N03AE01
ATC
clonazepam; systemic
3.1
6.1
25
84
M03BA52
ATC
carisoprodol, combinations excl. psycholeptics; oral
5.7
6.1
16
29
P06
ICPC
Sleep disturbance
2.3
6.0
48
226
C07AB07
ATC
bisoprolol; oral
1.7
6.0
157
1102
M01AH03
ATC
valdecoxib; oral
3.2
6.0
24
79
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
2.4
6.0
41
180
P01AB01
ATC
metronidazole; oral, rectal
1.7
6.0
153
1067
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
121
260
6.30
57.12
3.5
2.9
—
—
—
0
0
93
203
5.71
42.27
4.4
3.5
1.22
1.23
mmol/l
0.43
84
182
184
720
3.95
39.05
3.9
3.3
0.00
0.00
estimate
0.50
109
254
41
51
8.87
31.32
3.8
3.2
57.78
54.71
%
0.64
41
51
39
48
8.92
30.01
3.8
3.0
3.87
4.13
e9/l
0.34
39
48
34
35
10.55
29.85
2.0
1.9
1.58
1.66
mmol/l
0.22
34
35
38
47
8.85
29.11
2.6
2.4
16.37
16.69
%
0.09
14
29
205
1122
2.75
21.27
3.8
2.9
—
—
—
0
0
34
57
6.44
19.85
1.6
1.7
—
—
—
0
0
181
963
2.64
19.41
4.5
3.0
14.43
26.46
ng/l
3.26
116
597
226
1414
2.43
16.19
3.7
2.9
0.00
0.00
estimate
0.50
116
277
228
1436
2.42
16.04
3.7
3.0
0.00
0.00
estimate
-0.00
111
252
113
518
2.67
15.87
2.6
2.2
5.99
7.06
e6/l
0.23
102
464
225
1420
2.39
15.60
4.3
4.1
0.00
0.00
estimate
0.50
111
261
296
2155
2.56
14.25
5.5
3.5
11.10
10.52
mm/h
0.29
268
1992
190
1163
2.24
13.55
16.3
10.0
1.12
1.18
inr
1.05
129
369
132
710
2.30
12.70
2.3
2.1
111.03
274.17
u/l
1.07
116
666
94
438
2.51
12.46
1.3
1.2
1.32
16.55
u/ml
2.59
44
174
107
551
2.30
11.23
2.1
1.7
236905180.42
8351144.24
pmol/l
0.71
84
479
152
908
2.11
10.96
2.6
3.6
2.36
2.36
mmol/l
0.14
143
825
94
464
2.35
10.84
1.3
1.2
25.24
34.84
iu/ml
0.53
28
145
125
714
2.11
9.98
2.7
2.6
1.13
0.41
e6/l
0.41
98
527
15
12
12.94
8.94
1.9
1.6
—
—
—
0
0
287
2255
2.04
8.71
9.6
7.0
74.73
76.24
u/l
0.32
271
2124
15
13
11.95
8.64
1.9
1.5
—
—
—
0
0
18
37
5.05
8.44
2.1
1.6
—
—
—
0
0
15
14
11.09
8.36
1.9
1.5
—
—
—
0
0
145
931
1.89
7.98
3.0
2.7
—
—
—
0
0
166
1116
1.85
7.88
5.0
5.1
35.59
36.36
g/l
1.00
151
1059
296
2386
2.01
7.88
4.8
3.8
14.88
14.63
pmol/l
0.87
264
2182
229
1701
1.84
7.84
9.4
9.8
4.26
4.02
e9/l
0.63
212
1492
16
20
8.29
7.67
2.1
1.5
—
—
—
0
0
196
1397
1.81
7.61
5.8
5.7
56.05
56.66
%
0.30
185
1323
199
1429
1.80
7.50
6.7
5.8
28.96
28.82
%
0.06
189
1355
18
42
4.45
7.29
2.1
1.8
—
—
—
0
0
348
3020
2.45
7.10
15.6
10.0
86.40
85.61
ml/min/173m2
0.33
316
2449
103
613
1.93
7.01
2.2
1.7
0.59
1.07
mg/l
5.24
83
465
357
3141
2.66
6.94
18.3
11.0
16.08
22.69
mg/l
4.23
303
2391
20
55
3.78
6.56
1.3
1.3
—
—
—
0
0
14
19
7.60
6.47
1.4
1.1
8.88
0.69
u/ml
—
7
10
17
31
5.68
6.37
1.7
2.1
31.65
34.29
pg
1.49
17
31
16
29
5.71
6.06
2.1
1.7
—
—
—
0
0
17
44
3.99
6.05
1.9
1.5
—
—
—
0
0
126
838
1.74
5.84
2.8
2.3
50.52
66.02
u/l
1.84
110
788
326
2820
1.96
5.71
18.5
13.9
13.56
14.50
%
8.80
321
2773
163
1169
1.68
5.70
6.5
6.4
1.21
1.22
mmol/l
0.15
150
1084
71
400
1.95
5.59
2.3
1.7
1503.33
1206.01
nmol/l
2.01
52
305
17
37
4.76
5.55
1.9
1.5
—
—
—
0
0
78
457
1.88
5.46
3.2
3.0
2.45
2.44
mmol/l
0.14
67
410
17
48
3.66
5.38
2.0
1.5
—
—
—
0
0
180
1339
1.64
5.38
2.4
2.5
—
—
—
0
0
16
37
4.46
4.99
1.9
1.5
—
—
—
0
0
355
3215
2.19
4.74
17.2
12.5
3.99
3.95
mmol/l
1.62
348
3117
354
3204
2.17
4.71
17.1
12.4
139.60
139.71
mmol/l
0.32
346
3113
19
64
3.07
4.62
2.1
1.7
—
—
—
0
0
44
228
2.05
4.37
1.1
1.3
66.88
151.09
iu/ml
1.49
13
100
106
721
1.65
4.35
2.3
2.5
329.65
9958.15
umol/l
4.21
86
643
19
68
2.89
4.18
2.1
1.7
—
—
—
0
0
22
86
2.65
4.13
1.7
1.3
1.11
1.23
g/l
1.03
22
79
325
2896
1.74
4.03
5.4
4.4
2.02
1.86
mu/l
0.23
296
2662
63
382
1.77
3.91
2.1
1.8
—
—
—
0
0
370
3452
2.47
3.83
12.5
8.8
26.36
26.98
u/l
0.33
358
3343
21
84
2.59
3.78
1.7
1.3
0.22
0.25
g/l
0.87
21
78
12
31
3.96
3.52
1.0
1.1
—
—
—
0
0
14
47
3.05
3.44
2.8
2.1
128.71
133.38
g/l
0.21
14
39
94
658
1.57
3.35
1.4
1.3
0.58
1.89
u/ml
1.35
47
189
90
624
1.58
3.34
2.5
2.0
3.31
2.88
mg/l
0.94
72
534
177
1423
1.45
3.19
8.1
6.5
9.10
10.71
umol/l
3.62
161
1351
164
1302
1.45
3.15
6.3
7.2
1.22
1.21
mmol/l
0.24
94
1119
40
226
1.86
3.13
2.9
2.0
14.02
13.45
nmol/l
0.19
35
213
170
1368
1.43
3.00
3.6
2.6
111.12
102.48
ug/l
0.30
150
1269
256
2226
1.44
2.89
3.7
2.9
43.65
45.49
u/l
0.17
234
2115
19
83
2.36
2.89
2.2
1.6
—
—
—
0
0
85
607
1.51
2.74
4.1
3.3
859.12
1150.97
ng/l
0.37
69
503
10
29
3.51
2.71
1.9
1.3
258.20
167.82
pmol/l
—
10
29
56
366
1.62
2.65
3.4
2.2
2.35
2.36
g/l
0.05
51
342
43
263
1.71
2.61
1.9
1.7
—
—
—
0
0
16
68
2.41
2.59
3.4
4.7
17.47
35.06
mg/l
—
6
55
6
11
5.52
2.55
4.2
5.1
—
—
—
0
0
17
77
2.26
2.41
1.5
1.7
—
—
—
0
0
9
27
3.39
2.40
1.6
1.2
—
—
—
0
0
18
84
2.20
2.38
1.8
1.5
—
0.01
—
0
16
17
337
0.48
2.34
3.3
3.9
34.17
31.66
%
0.54
12
232
42
264
1.66
2.32
1.8
1.6
—
—
—
0
0
142
1148
1.37
2.30
2.7
2.2
80.00
73.81
nmol/l
1.94
133
1054
14
60
2.38
2.24
1.1
1.3
456.75
233.00
u/ml
—
8
34
379
3651
2.48
2.23
24.8
16.6
255.58
253.43
e9/l
0.27
373
3555
15
67
2.29
2.20
3.5
4.7
—
1.18
—
0
8
8
24
3.38
2.19
1.1
1.3
—
—
—
0
0
250
2218
1.36
2.17
3.0
3.2
—
—
—
0
0
379
3655
2.44
2.15
24.8
16.5
4.52
4.55
e12/l
0.73
373
3553
15
68
2.25
2.13
3.6
4.6
38.34
58.48
mg/l
—
5
55
24
131
1.89
2.13
1.5
1.3
365.28
303.08
mu/l
0.30
18
119
103
799
1.39
2.12
1.6
1.6
1.43
1.41
mmol/l
0.06
62
677
7
20
3.54
2.06
1.1
1.1
—
—
—
0
0
14
63
2.27
2.03
1.9
1.9
169.73
111.15
ug/min
—
9
36
14
63
2.27
2.03
1.2
1.6
—
—
—
0
0
8
26
3.12
2.02
1.1
1.1
—
—
—
0
0
7
21
3.37
1.97
1.3
1.3
70.14
79.38
umol/l
—
7
21
15
71
2.16
1.95
1.9
2.4
—
—
—
0
0
8
27
3.00
1.94
1.1
1.1
—
—
—
0
0
378
3654
2.22
1.90
24.7
16.6
40.97
40.80
%
0.31
371
3436
311
2880
1.40
1.90
5.2
4.8
38.73
39.04
mmol/mol
0.25
270
2700
12
52
2.35
1.89
1.6
1.4
4564.86
9379.93
e6/l
—
7
41
48
329
1.52
1.88
3.7
2.3
24.37
24.24
%
0.02
43
286
6
17
3.57
1.84
1.5
1.8
—
—
—
0
0
5
12
4.21
1.83
1.2
1.1
1703.40
1407.50
miu/ml
—
5
12
55
391
1.47
1.82
3.5
2.3
14.22
13.89
umol/l
0.09
50
370
8
29
2.79
1.80
1.1
1.0
—
—
—
0
0
11
48
2.33
1.72
6.2
5.0
126.91
176.13
u/ml
0.16
11
43
6
20
3.03
1.58
2.0
1.7
—
—
—
0
0
80
624
1.36
1.58
1.8
1.5
—
—
—
0
0
7
27
2.62
1.52
1.1
1.1
—
—
—
0
0
27
171
1.62
1.50
1.3
1.4
22.93
25.95
iu/l
0.22
21
157
13
65
2.03
1.50
1.1
1.3
—
—
—
0
0
19
109
1.78
1.49
1.9
2.0
153.13
2285.44
u/l
—
9
47
49
659
0.71
1.48
2.6
2.2
—
—
—
0
0
5
16
3.15
1.44
1.6
1.4
1.56
2.06
mmol/l
—
5
16
(40770918) von Willebrand factor (vWf).activity actual/normal in Platelet poor plasma by Immunoassay
5
17
2.97
1.36
1.4
2.8
153.60
125.47
%
—
5
17
9
45
2.02
1.24
1.2
1.1
—
—
—
0
0
26
380
0.66
1.23
1.7
1.7
—
—
—
0
0
16
94
1.73
1.19
1.3
1.6
—
—
—
0
0
36
490
0.71
1.18
3.5
3.5
27.71
330.81
ng/l
3.20
24
356
25
167
1.53
1.15
1.5
1.7
—
—
—
0
0
14
81
1.76
1.10
1.4
1.3
227.00
324.90
ug/g
—
6
46
5
21
2.40
1.09
1.6
4.4
—
—
—
0
0
32
230
1.43
1.05
1.6
2.5
69.44
68.50
ml/min/173m2
0.04
16
90
11
60
1.86
1.04
1.7
1.5
—
—
—
0
0
118
1022
1.22
1.02
4.8
3.4
32.05
31.05
u/l
0.09
107
983
10
53
1.91
1.02
1.0
1.2
—
—
—
0
0
9
48
1.90
1.01
1.1
1.2
—
1.00
—
0
5
6
27
2.24
0.94
1.0
1.1
—
—
—
0
0
27
195
1.41
0.89
1.5
1.6
—
—
—
0
0
95
818
1.21
0.87
4.3
3.8
12.78
10.21
mg/mmol
0.14
54
521
50
400
1.29
0.87
2.5
2.3
29.80
29.54
s
0.13
50
389
12
72
1.69
0.86
2.8
4.2
1.23
1.29
mmol/l
0.08
12
72
323
3106
1.24
0.82
4.1
3.9
5.86
5.83
mmol/l
0.24
292
2874
21
147
1.45
0.82
4.2
3.7
2.72
1.77
mmol/l
0.80
15
110
8
47
1.72
0.81
1.4
1.1
—
—
—
0
0
23
165
1.42
0.79
1.1
1.0
—
—
—
0
0
7
123
0.56
0.79
1.0
1.6
—
—
—
0
0
0
26
0.00
0.78
0.0
1.3
—
—
—
0
0
323
3113
1.22
0.76
3.8
3.6
1.41
1.30
mmol/l
1.36
290
2921
11
67
1.66
0.76
3.0
3.3
3.68
3.84
mmol/l
0.58
11
67
61
721
0.82
0.73
3.5
3.8
17.21
21.06
%
1.35
28
298
7
39
1.81
0.73
2.3
1.5
—
—
—
0
0
12
182
0.65
0.72
1.8
1.8
—
—
—
0
0
53
438
1.24
0.72
2.0
1.8
1.42
1.38
%
0.12
44
390
11
68
1.64
0.72
2.0
1.2
—
—
—
0
0
18
127
1.44
0.69
1.7
1.7
—
—
—
0
0
17
236
0.71
0.67
1.6
1.8
—
—
—
0
0
12
79
1.54
0.63
1.3
1.1
—
—
—
0
0
33
409
0.79
0.61
2.8
2.6
3.33
2.63
e6/l
0.17
16
219
5
30
1.68
0.61
2.2
3.9
23.20
57.24
u/ml
—
5
30
8
50
1.61
0.61
1.4
1.8
—
—
—
0
0
97
865
1.16
0.60
4.5
4.2
2.14
2.37
ug/l
0.14
83
792
0
21
0.00
0.60
0.0
9.7
—
50.11
—
0
9
12
81
1.50
0.57
1.3
1.3
—
—
—
0
0
6
37
1.63
0.56
1.0
1.1
—
—
—
0
0
18
136
1.34
0.50
1.3
1.5
—
—
—
0
0
67
592
1.16
0.48
1.4
1.4
19.31
21.15
nmol/l
0.35
56
507
46
394
1.19
0.47
2.1
1.9
—
—
—
0
0
5
33
1.52
0.41
1.2
1.7
—
—
—
0
0
5
33
1.52
0.41
1.2
1.7
—
—
—
0
0
0
15
0.00
0.41
0.0
4.7
—
111.40
—
0
15
0
15
0.00
0.41
0.0
1.1
—
178.09
—
0
15
0
16
0.00
0.41
0.0
1.5
—
—
—
0
0
0
17
0.00
0.40
0.0
1.7
—
—
—
0
0
0
17
0.00
0.40
0.0
1.7
—
—
—
0
0
7
105
0.66
0.40
2.4
2.0
—
—
—
0
0
5
36
1.39
0.38
1.0
1.3
—
—
—
0
0
18
143
1.27
0.37
5.6
11.1
26.05
24.62
mmol/l
1.13
18
135
330
3235
1.13
0.36
4.3
4.0
4.81
4.77
mmol/l
0.29
298
3063
334
3281
1.13
0.32
4.6
4.3
2.88
2.87
mmol/l
0.04
302
3079
328
3219
1.12
0.32
4.3
4.0
1.47
1.47
mmol/l
0.01
294
3025
7
97
0.72
0.31
2.0
1.8
—
—
—
0
0
49
442
1.12
0.28
2.2
2.0
—
—
—
0
0
16
133
1.21
0.24
1.6
1.3
—
—
—
0
0
49
533
0.91
0.22
2.7
2.6
0.57
0.74
ug/l
1.31
30
315
40
439
0.90
0.22
2.1
2.4
1.90
1.06
e6/l
0.48
21
248
5
42
1.19
0.21
1.0
1.1
—
—
—
0
0
0
10
0.00
0.21
0.0
2.1
—
—
—
0
0
0
10
0.00
0.21
0.0
2.1
—
—
—
0
0
0
10
0.00
0.21
0.0
2.1
—
—
—
0
0
0
12
0.00
0.21
0.0
1.0
—
—
—
0
0
35
317
1.11
0.20
9.0
5.5
—
—
—
0
0
106
1011
1.07
0.20
1.7
1.8
92.25
94.15
pmol/l
0.18
61
547
6
52
1.16
0.19
2.5
1.5
—
—
—
0
0
33
301
1.11
0.17
4.0
2.6
5.59
6.77
umol/l
0.36
23
258
5
67
0.74
0.17
1.2
1.8
0.81
0.82
nmol/l
—
5
54
9
106
0.85
0.13
1.8
1.5
—
—
—
0
0
13
147
0.88
0.11
3.3
9.0
1.43
1.47
%
0.06
13
147
13
147
0.88
0.11
3.3
9.3
0.80
0.68
%
0.62
13
147
16
144
1.12
0.10
3.0
2.4
0.03
0.18
e6/l
1.82
16
135
17
154
1.11
0.10
1.1
1.3
—
—
—
0
0
12
135
0.89
0.10
1.2
1.5
—
—
—
0
0
5
47
1.06
0.09
2.6
1.7
12.60
12.96
%
—
5
47
11
124
0.88
0.09
1.5
1.5
—
—
—
0
0
21
195
1.08
0.08
2.8
4.2
78.37
78.35
ng/l
0.00
15
180
11
123
0.89
0.08
1.1
1.4
197.57
258.36
miu/ml
—
6
60
13
143
0.91
0.07
3.4
9.5
92.11
94.00
%
0.30
13
143
8
94
0.85
0.06
1.8
1.6
—
—
—
0
0
12
127
0.94
0.01
3.7
2.5
1.23
1.13
%
0.20
12
127
29
297
0.97
0.01
3.6
6.9
104.59
104.51
mmol/l
0.03
29
297
12
114
1.05
0.00
1.4
1.4
—
—
—
0
0
12
114
1.05
0.00
1.4
1.4
—
—
—
0
0
60
594
1.01
0.00
1.6
1.5
—
—
—
0
0
12
115
1.04
0.00
1.4
1.4
—
—
—
0
0
12
115
1.04
0.00
1.4
1.4
—
—
—
0
0
12
124
0.97
0.00
3.7
2.4
0.55
0.64
%
0.42
12
124
23
226
1.02
0.00
3.7
11.2
125.09
121.57
g/l
0.34
23
220
5
49
1.02
0.00
1.2
1.7
—
—
—
0
0
0
6
0.00
0.00
0.0
1.3
—
—
—
0
0
5
49
1.02
0.00
1.2
1.7
—
—
—
0
0
8
85
0.94
0.00
1.5
1.9
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.0
—
—
—
0
0
5
55
0.91
-0.00
1.0
1.7
—
—
—
0
0
6
61
0.98
-0.00
1.3
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
9
0.00
-0.00
0.0
2.1
—
62.73
—
0
9
7
78
0.90
-0.00
1.0
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
2.6
—
57.46
—
0
5
0
5
0.00
-0.00
0.0
1.8
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.1
—
—
—
0
0
5
51
0.98
-0.00
1.0
1.4
—
—
—
0
0
7
79
0.88
-0.00
1.0
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint M13_FATPADHYPERTROPHY and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| M13_FATPADHYPERTROPHY | 1.243 [0.99, 1.57] | 0.065 |
| Birth year | 0.993 [0.98, 1.0] | 0.123 |
During the follow-up period (1.1.1998 — 31.12.2019), 97 out of 968 females with M13_FATPADHYPERTROPHY died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| M13_FATPADHYPERTROPHY | 1.002 [0.78, 1.29] | 0.987 |
| Birth year | 0.99 [0.98, 1.0] | 0.092 |
During the follow-up period (1.1.1998 — 31.12.2019), 68 out of 711 males with M13_FATPADHYPERTROPHY died.
Mortality risk
Mortality risk for people of age
years, who have M13_FATPADHYPERTROPHY.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.089% | 0.239% |
| 5 | 0.548% | 1.293% |
| 10 | 1.615% | 3.128% |
| 15 | 3.274% | 6.069% |
| 20 | 5.57% | 10.718% |
Relationships between endpoints
↥Index endpoint: M13_FATPADHYPERTROPHY – Hypertrophy of (infrapatellar) fat pad
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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