Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease

E4_HYPERURI

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 E79.0
  • Cause of death: ICD-10 E79.0

2 out of 7 registries used, show all original rules.

162

4. Check minimum number of events

None

162

5. Include endpoints

None

162

6. Filter based on genotype QC (FinnGen only)

162

Control definitions (FinnGen only)

Control exclude
E4_METABOLIA

Extra metadata

Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
E79
Name in latin
Hyperurichaemia sine symptomatibus arthritidis inflammatoriae sive morbi tophacei

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 1098 486 606
Only index persons 956 413 543
Unadjusted period prevalence (%)
Whole population 0.02 0.01 0.02
Only index persons 0.02 0.02 0.02
Median age at first event (years)
Whole population 67.61 70.73 65.06
Only index persons 65.92 68.15 64.22

-FinnGen-

Key figures

All Female Male
Number of individuals 162 58 104
Unadjusted period prevalence (%) 0.04 0.02 0.05
Median age at first event (years) 65.33 62.56 66.88

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
149
Matched controls
1489
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
E79.0
ICD-10 Finland
Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease
+∞
215.4
149
*
M04AA01
ATC
allopurinol; systemic
15.4
46.4
92
141
M10.9
ICD-10 Finland
Gout, unspecified
9.8
19.8
42
57
202
Kela drug reimbursment
Connective tissue diseases, rheumatoid arthritis and comparable disease
7.5
15.7
39
67
N18.9
ICD-10 Finland
Chronic kidney disease, unspecified
9.3
15.5
33
44
C03CA01
ATC
furosemide; systemic
4.2
15.0
76
293
M10.0
ICD-10 Finland
Idiopathic gout
15.7
14.3
23
17
H02AB06
ATC
prednisolone; systemic
3.9
13.8
99
504
212
Kela drug reimbursment
Gout
15.0
13.4
22
17
N17.9
ICD-10 Finland
Acute renal failure, unspecified
14.2
12.0
20
16
M13.9
ICD-10 Finland
Arthritis, unspecified
7.1
11.6
29
49
C10AA05
ATC
atorvastatin; oral
3.4
11.4
81
388
A46
ICD-10 Finland
Erysipelas
4.7
10.9
40
108
GD1AA
NOMESCO Finland
Thorax X-ray examination
3.2
10.6
89
472
NK4XE
NOMESCO Finland
Joint ultrasound examination not elsewhere classified
7.1
10.2
25
41
C07AB07
ATC
bisoprolol; oral
3.1
10.0
96
547
I50.9
ICD-10 Finland
Heart failure, unspecified
4.2
9.7
40
120
I10
ICD-10 Finland
Essential (primary) hypertension
3.1
9.5
108
680
J01FF01
ATC
clindamycin; systemic
3.3
9.5
59
246
205
Kela drug reimbursment
Chronic hypertension
3.1
9.5
69
324
TNX10
NOMESCO Finland
Arthrocentesis, unspecified region, unspecified region
6.3
9.4
25
46
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
4.3
9.3
36
102
P01BA02
ATC
hydroxychloroquine; oral
5.6
9.1
27
57
C08CA01
ATC
amlodipine; oral
2.9
8.9
77
399
A10BH05
ATC
linagliptin; oral
6.8
8.9
22
37
NH3BA
NOMESCO Finland
Foot and toes extensive X-ray examination
12.7
8.8
15
13
ND2BA
NOMESCO Finland
Hand and fingers extensive X-ray examination
53.2
8.8
10
*
E78.00
ICD-10 Finland
Familial hypercholesterolaemia
53.2
8.8
10
*
M04AA03
ATC
febuxostat; oral
53.2
8.8
10
*
288
Kela drug reimbursment
Febuxostat
29.5
8.6
11
*
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
6.4
8.5
22
39
R06.0
ICD-10 Finland
Dyspnoea
3.3
8.5
49
192
E86
ICD-10 Finland
Volume depletion
+∞
8.4
8
*
M06.0
ICD-10 Finland
Seronegative rheumatoid arthritis
12.7
8.3
14
12
L28
ICPC
Limited function/disability (L)
3.5
8.2
41
144
E78.9
ICD-10 Finland
Disorder of lipoprotein metabolism, unspecified
18.5
8.2
12
7
TND11
NOMESCO Finland
Injection of diagnostic or therapeutic substance in joint, wrist or hand
18.5
8.2
12
7
E78.01
ICD-10 Finland
Pure hypercholesterolaemia
4.2
8.2
32
91
349
Kela drug reimbursment
Febuxostat
35.5
8.2
10
*
A10BA02
ATC
metformin; oral
2.9
8.2
62
290
C10AA01
ATC
simvastatin; oral
2.8
8.1
85
484
J01DB01
ATC
cefalexin; oral
3.5
8.0
129
961
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
3.6
8.0
39
135
L04AX03
ATC
methotrexate; systemic (immunosuppressants)
5.1
7.9
25
57
215
Kela drug reimbursment
Diabetes, non-insulin-treated
3.0
7.9
54
234
103
Kela drug reimbursment
Diabetes, insulin-treated
2.9
7.9
59
275
A49.9
ICD-10 Finland
Bacterial infection, unspecified
4.4
7.9
29
78
FN1AC
NOMESCO Finland
Angiography of heart and/or coronary arteries
3.1
7.7
48
196
A07EC01
ATC
sulfasalazine; oral, rectal
5.1
7.7
24
54
C03DA01
ATC
spironolactone; oral
4.2
7.6
29
81
E78.5
ICD-10 Finland
Hyperlipidaemia, unspecified
9.1
7.5
15
18
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
3.3
6.9
37
134
N19
ICD-10 Finland
Unspecified kidney failure
8.5
6.8
14
18
H02AB07
ATC
prednisone; oral
3.5
6.7
32
108
E11.7
ICD-10 Finland
Type 2 diabetes mellitus, with multiple complications
5.4
6.6
19
39
G47.3
ICD-10 Finland
Sleep apnoea
2.9
6.5
43
182
M07.3*L40.5
ICD-10 Finland
Other psoriatic arthropathies
11.8
6.4
11
10
AN1
HP
Coronary angiography
3.5
6.3
29
95
E66.01
ICD-10 Finland
Obesity due to excess calories
5.7
6.2
17
33
E11.9
ICD-10 Finland
Type 2 diabetes mellitus, without complications
2.7
6.2
48
221
A10AE05
ATC
insulin detemir; parenteral
6.0
6.2
16
29
N02BE01
ATC
paracetamol; systemic, rectal
3.4
6.2
134
1077
A10AC01
ATC
insulin (human); parenteral (insulins and analog. for injection, intermediate-acting)
4.7
6.1
20
48
J01MA12
ATC
levofloxacin; systemic
2.8
6.1
41
176
M05.8
ICD-10 Finland
Other seropositive rheumatoid arthritis
5.8
6.0
16
30

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
unit
cases
controls
-log10(p)
N cases
N controls
(3026493) Urate [Moles/volume] in Serum or Plasma
115
356
8.69
40.19
6.1
2.6
umol/l
434.2
7842.7
1.75
105
300
(40763571) Iron/Transferrin [Ratio] in Serum or Plasma
60
187
4.51
18.00
5.0
2.1
%
18.7
23.5
2.37
54
159
(3023520) Reticulocytes [#/volume] in Blood
42
109
4.85
15.68
3.3
3.3
e9/l
75.2
71.7
0.27
32
89
(3023368) Bacteria identified in Blood by Culture
85
368
3.76
15.61
6.9
4.7
—
—
—
0
0
(3002032) Base excess in Venous blood by calculation
42
110
4.80
15.50
10.0
3.6
mmol/l
2.2
2.2
0.01
30
83
(3016431) Calcium.ionized [Moles/volume] adjusted to pH 7.4 in Serum or Plasma
116
624
4.03
15.13
16.7
6.6
mmol/l
1.2
1.2
0.94
95
527
(1616796) Gas panel - Central venous blood
18
20
10.00
14.95
7.9
2.5
—
—
—
0
0
(3021347) Calcium.ionized [Moles/volume] in Serum or Plasma
110
577
3.82
14.78
15.3
6.0
mmol/l
1.2
1.2
0.92
102
517
(3012544) pH of Venous blood
42
114
4.62
14.78
9.9
3.9
—
—
—
0
0
(3027945) Reticulocytes/100 erythrocytes in Blood
48
156
3.95
13.17
2.8
2.9
%
2.1
1.8
1.11
42
143
(3012336) Haptoglobin [Mass/volume] in Serum or Plasma
28
59
5.53
13.17
2.0
1.8
g/l
1.7
1.4
0.66
23
50
(3001604) Monocytes [#/volume] in Blood
113
636
3.57
12.91
8.8
6.0
e9/l
0.7
0.6
1.39
103
559
(3007628) Bicarbonate [Moles/volume] standard in Venous blood
25
49
5.85
12.67
9.2
5.1
mmol/l
24.6
23.7
0.62
20
41
(3006315) Basophils [#/volume] in Blood
113
641
3.52
12.64
9.2
6.0
e9/l
0.0
0.0
0.07
104
568
(40771025) 25-Hydroxyvitamin D3+25-Hydroxyvitamin D2 [Moles/volume] in Serum or Plasma
93
479
3.21
12.06
3.0
2.0
nmol/l
72.5
76.3
0.57
86
418
(3044938) Influenza virus A RNA [Presence] in Specimen by NAA with probe detection
57
220
3.45
11.97
2.1
1.9
—
—
—
0
0
(3019198) Lymphocytes [#/volume] in Blood
112
650
3.34
11.70
9.4
6.1
e9/l
1.8
1.9
0.24
104
587
(3013115) Eosinophils [#/volume] in Blood
113
662
3.34
11.56
9.3
6.1
e9/l
0.2
0.2
0.30
102
596
(3038288) Influenza virus B RNA [Presence] in Specimen by NAA with probe detection
47
165
3.60
11.38
1.9
1.8
—
—
—
0
0
(3051552) Clostridioides difficile toxin genes [Presence] in Stool by NAA with probe detection
33
90
4.35
11.38
2.6
1.5
—
—
—
0
0
(3017817) Protein [Mass] in Urine collected for unspecified duration
12
11
11.70
11.19
2.4
1.1
—
—
—
0
0
(3004588) Protein electrophoresis panel - Serum or Plasma
33
93
4.20
10.88
2.1
1.5
—
—
—
0
0
(3020682) Albumin/Creatinine [Ratio] in Urine
79
391
2.99
10.65
6.2
3.7
mg/mmol
28.4
4.9
2.54
64
243
(3043924) Respiratory syncytial virus RNA [Identifier] in Specimen by NAA with probe detection
46
166
3.47
10.61
1.8
1.7
—
—
—
0
0
(3009508) Creatinine [Moles/volume] in Urine
78
384
2.99
10.61
5.0
3.0
mmol/l
6.4
7.9
3.11
70
309
(3013650) Neutrophils [#/volume] in Blood by Automated count
118
730
3.27
10.58
13.7
10.1
e9/l
4.7
4.0
2.70
111
658
(3007220) Creatine kinase [Enzymatic activity/volume] in Serum or Plasma
77
377
2.99
10.57
2.3
2.0
u/l
153.3
169.6
0.24
72
350
(3041942) Cyclic citrullinated peptide Ab [Units/volume] in Serum
51
197
3.32
10.55
1.3
1.3
u/ml
31.7
10.1
0.89
18
72
(36305247) Microscopic observation [Identifier] in Isolate by Gram stain
19
34
6.20
10.49
1.3
1.3
—
—
—
0
0
(3018418) pH of Serum or Plasma
78
386
2.97
10.48
10.5
3.9
ph
7.4
7.4
0.27
20
77
(3042936) Bacteria identified in Isolate by Culture
52
205
3.26
10.38
3.1
2.1
—
—
—
0
0
(3026782) Osmolality of Urine
58
244
3.15
10.38
4.5
2.5
mosm/kgh2o
502.7
567.2
1.97
52
200
(3032080) INR in Blood by Coagulation assay
98
553
2.95
10.26
13.7
10.1
inr
1.3
1.3
0.05
25
148
(3026008) Bacteria identified in Urine by Culture
75
367
2.94
10.23
3.4
2.8
—
—
—
0
0
(3020891) Body temperature
26
64
4.65
10.14
8.6
3.4
—
—
—
0
0
(3000991) Gas panel - Venous blood
33
98
3.97
10.10
21.8
7.1
—
—
—
0
0
(586526) SARS-CoV-2 (COVID-19) RNA [Presence] in Nasopharynx by NAA with probe detection
28
74
4.37
10.00
1.9
1.2
—
—
—
0
0
(3012516) Albumin [Mass/volume] in Urine
75
371
2.90
9.98
4.9
3.0
mg/l
146.6
34.6
2.92
59
241
(3003396) Base excess in Arterial blood by calculation
43
156
3.39
9.77
11.9
8.8
mmol/l
1.4
1.6
0.09
31
120
(43054903) Holo-transcobalamin II [Moles/volume] in Serum
93
528
2.79
9.34
2.5
2.0
pmol/l
76.3
95.9
4.16
56
288
(3014007) Fractional oxyhemoglobin in Arterial blood
29
83
4.04
9.30
15.6
6.6
%
89.5
93.5
0.59
29
83
(40767503) Oxygen content in Capillary blood by calculation
14
21
7.20
9.05
6.1
2.4
%
16.9
16.6
—
9
10
(40760892) CBC W Ordered Manual Differential panel - Blood
59
270
2.86
8.90
6.4
5.7
—
—
—
0
0
(3037522) Nuclear Ab [Titer] in Serum
41
153
3.25
8.84
1.3
1.3
titre
323.6
544.7
0.61
11
34
(42870588) Differential panel, method unspecified - Blood
79
424
2.68
8.70
9.8
5.9
—
—
—
0
0
(3029287) Urinalysis microscopic panel [#/volume] - Urine by Automated count
87
493
2.65
8.54
6.2
2.9
—
—
—
0
0
(3037467) Urinalysis macro (dipstick) panel - Urine
127
872
3.11
8.50
6.4
4.1
—
—
—
0
0
(3050238) Crystals [Presence] in Synovial fluid by Light microscopy
18
38
5.20
8.34
1.4
1.2
—
—
—
0
0
(3015399) Transferrin receptor.soluble [Mass/volume] in Serum or Plasma
64
316
2.69
8.24
3.0
2.0
mg/l
4.0
3.3
1.20
57
277
(3019060) Gas panel - Arterial blood
31
102
3.52
8.11
4.9
8.5
—
—
—
0
0
(21494890) Protein electrophoresis panel - 24 hour Urine
10
12
8.82
7.66
1.2
1.2
—
—
—
0
0
(3001122) Ferritin [Mass/volume] in Serum or Plasma
85
501
2.47
7.36
5.4
2.4
ug/l
228.3
157.5
1.02
77
458
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
15
30
5.41
7.34
4.5
2.0
u/ml
0.2
0.3
—
10
17
(3021614) Rheumatoid factor [Units/volume] in Serum or Plasma
46
202
2.78
7.33
1.5
1.3
iu/ml
49.2
29.3
0.41
17
63
(3021440) Promyelocytes/100 leukocytes in Blood
30
103
3.35
7.32
3.8
5.5
%
0.6
0.2
0.87
11
37
(3004529) Oxygen [Partial pressure] adjusted to patient's actual temperature in Venous blood
23
66
3.90
7.30
8.5
2.7
%
58.1
45.0
1.85
23
66
(3029187) Natriuretic peptide.B prohormone N-Terminal [Mass/volume] in Serum or Plasma
76
427
2.47
7.30
6.2
3.2
ng/l
3320.3
1098.7
1.73
69
361
(3024403) Complement+Immunoglobulin [Units/volume] in Red Blood Cells
18
43
4.58
7.22
1.8
1.6
—
—
—
0
0
(3008909) Norovirus RNA [Presence] in Stool by NAA with probe detection
15
31
5.23
7.08
1.8
1.2
—
—
—
0
0
(3021601) Nitrite [Presence] in Urine by Test strip
98
625
2.44
7.01
7.4
4.6
estimate
0.0
0.0
0.00
26
118
(3035350) Ketones [Presence] in Urine by Test strip
98
626
2.43
6.97
6.0
3.6
estimate
0.0
0.0
0.00
25
119
(3017181) Myelocytes/100 leukocytes in Blood
31
112
3.19
6.96
4.0
5.2
%
0.7
1.2
0.61
11
43
(3010566) Parathyrin.intact [Moles/volume] in Serum or Plasma
11
17
6.87
6.87
5.0
1.6
—
—
—
0
0
(3030692) Respiratory virus DNA+RNA [Identifier] in Specimen by NAA with probe detection
12
21
6.09
6.69
1.6
1.4
—
—
—
0
0
(3018677) aPTT in Platelet poor plasma by Coagulation assay
46
212
2.63
6.61
3.2
1.7
s
29.4
29.2
0.13
46
202
(3009261) Glucose [Presence] in Urine by Test strip
98
640
2.34
6.44
6.0
3.6
estimate
0.0
0.0
0.00
24
118
(3030467) Casts [#/volume] in Urine by Automated count
66
364
2.37
6.44
5.4
3.0
e6/l
0.6
0.4
0.46
58
272
(40765161) Human bocavirus DNA [Presence] in Specimen by NAA with probe detection
13
26
5.35
6.34
2.1
1.8
—
—
—
0
0
(3013707) Erythrocyte sedimentation rate by Westergren method
128
947
2.68
6.27
7.4
4.3
mm/h
22.9
13.0
6.38
123
866
(3000850) Epithelial cells [#/volume] in Urine
54
277
2.42
6.15
4.1
2.6
e6/l
5.5
4.3
0.34
49
242
(3018095) Leukocytes [#/volume] in Urine
76
454
2.27
6.07
6.1
3.4
e6/l
367.9
91.1
0.50
62
341
(3005785) Creatine kinase.MB [Mass/volume] in Serum or Plasma
32
128
2.87
5.99
3.0
2.4
ug/l
3.3
7.5
1.40
27
115
(43055554) Base excess.100% oxygenated [Moles/volume] standard in Capillary blood by calculation
24
81
3.30
5.98
5.9
2.8
mmol/l
3.3
1.8
0.77
15
64
(3042194) Human metapneumovirus RNA [Presence] in Specimen by NAA with probe detection
15
36
4.49
5.96
2.1
1.7
—
—
—
0
0
(3020565) Legionella pneumophila DNA [Presence] in Specimen by NAA with probe detection
12
24
5.32
5.84
2.0
1.5
—
—
—
0
0
(3009343) pH of Capillary blood
25
88
3.18
5.82
6.0
2.7
ph
7.4
7.4
—
6
9
(3040853) Adenovirus DNA [Identifier] in Specimen by NAA with probe detection
15
37
4.37
5.77
2.1
1.7
—
—
—
0
0
(3012477) Bordetella pertussis DNA [Presence] in Specimen by NAA with probe detection
13
29
4.79
5.62
2.1
1.4
—
—
—
0
0
(3031040) Bacteria [#/volume] in Urine by Automated count
116
841
2.34
5.61
5.8
4.3
—
3690.6
—
0
16
(3002582) Erythrocytes [#/volume] in Urine
68
400
2.21
5.53
5.4
3.1
e6/l
97.5
217.7
0.32
58
314
(3002179) Metamyelocytes/100 leukocytes in Blood
26
97
3.00
5.49
2.9
5.2
%
0.2
0.5
—
5
28
(36304419) Bacteria [Presence] in Urine
62
353
2.23
5.45
5.4
3.0
—
—
—
0
0
(3015377) Calcium [Moles/volume] in Serum or Plasma
72
436
2.17
5.42
3.2
3.3
mmol/l
2.3
2.4
0.43
65
373
(40761535) Cells panel - Urine sediment
29
116
2.83
5.41
6.0
3.4
—
—
—
0
0
(3008898) HLA-B27 [Presence]
13
30
4.62
5.40
1.1
1.0
—
—
—
0
0
(3021960) Folate [Moles/volume] in Serum or Plasma
59
334
2.21
5.22
2.1
1.6
nmol/l
18.5
20.7
0.55
52
281
(46236952) Glomerular filtration rate/1.73 sq M.predicted [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (MDRD)
26
100
2.91
5.20
5.2
2.6
ml/min/173m2
32.9
65.1
6.83
17
38
(3029937) Albumin [Presence] in Urine by Test strip
63
367
2.17
5.18
6.5
4.0
estimate
0.0
0.0
0.00
21
117
(3031478) Chlamydophila pneumoniae DNA [Presence] in Specimen by NAA with probe detection
12
27
4.72
5.13
1.8
1.4
—
—
—
0
0
(3019309) Folate [Moles/volume] in Red Blood Cells
49
259
2.28
5.10
2.2
1.6
nmol/l
1407.3
1192.8
0.84
41
197
(3025159) Blasts/100 leukocytes in Blood
25
96
2.90
5.01
3.8
5.6
%
0.0
0.0
—
6
30
(3019800) Troponin T.cardiac [Mass/volume] in Serum or Plasma
82
534
2.08
5.00
6.7
3.5
ng/l
43.4
37.1
0.35
65
392
(3002482) Mycoplasma pneumoniae DNA [Presence] in Specimen by NAA with probe detection
13
32
4.33
5.00
2.2
1.4
—
—
—
0
0
(3007164) IgA [Mass/volume] in Serum or Plasma
42
210
2.35
4.96
2.0
1.4
g/l
3.1
2.9
0.17
32
124
(3007853) Bacteria identified in Skin by Aerobe culture
34
156
2.49
4.83
2.4
1.6
—
—
—
0
0
(3009445) Proteinase 3 Ab [Units/volume] in Serum
18
59
3.31
4.68
1.4
1.4
—
—
—
0
0
(40758558) Short blood count panel - Blood
56
323
2.12
4.65
11.9
6.4
—
—
—
0
0
(3017143) Hepatitis C virus Ab [Presence] in Serum
28
119
2.64
4.64
2.4
1.6
—
—
—
0
0
(3011397) Hemoglobin [Presence] in Urine by Test strip
50
280
2.14
4.45
6.4
3.8
—
—
—
0
0
(3021589) Normoblasts [#/volume] in Blood
82
553
1.98
4.37
18.0
9.5
e9/l
0.0
0.0
0.50
73
458
(3028626) Oxygen [Partial pressure] in Capillary blood
13
36
3.84
4.30
5.5
2.1
kpa
8.5
8.1
0.20
13
30
(3043723) Beta 1 globulin [Mass/volume] in Serum or Plasma by Electrophoresis
17
57
3.21
4.27
1.4
1.3
—
—
—
0
0
(3021901) Oxygen saturation in Capillary blood
11
27
4.30
4.23
5.7
2.2
—
—
—
0
0
(3042111) Morphology [Interpretation] in Bone marrow Narrative
12
32
3.97
4.17
1.4
2.0
—
—
—
0
0
(3030306) Epithelial cells.non-squamous [#/volume] in Urine by Automated count
42
225
2.17
4.16
4.2
2.6
e6/l
0.8
0.9
0.11
29
133
(3025941) Bacteria identified in Stool by Culture
17
58
3.16
4.15
1.5
1.3
—
—
—
0
0
(3022806) Fractional oxyhemoglobin in Capillary blood
9
14
6.73
4.04
3.1
1.1
%
89.8
88.0
—
9
14
(3023465) Gamma globulin [Mass/volume] in Serum or Plasma by Electrophoresis
16
54
3.18
3.97
1.4
1.3
g/l
10.0
11.0
0.53
16
48
(3001079) Blood group antibody screen [Presence] in Serum or Plasma
84
585
1.91
3.95
5.7
4.3
—
—
—
0
0
(3048816) Calcium.ionized [Moles/volume] adjusted to pH 7.4 in Blood
24
103
2.56
3.89
8.0
3.7
mmol/l
1.2
1.2
0.05
24
93
(3019284) Hepatitis B virus surface Ag [Presence] in Serum
28
130
2.39
3.85
2.4
1.6
—
—
—
0
0
(3029879) Epithelial cells.squamous [#/volume] in Urine by Automated count
38
202
2.15
3.81
4.4
2.8
e6/l
3.1
1.1
1.02
24
112
(3028286) Albumin [Mass/volume] in Serum or Plasma by Electrophoresis
15
50
3.20
3.80
1.4
1.2
g/l
36.0
36.8
0.17
15
43
(44790048)
9
17
5.54
3.56
2.4
1.4
—
—
—
0
0
(44790049)
9
17
5.54
3.56
2.4
1.4
—
—
—
0
0
(44790047)
9
17
5.54
3.56
2.4
1.4
—
—
—
0
0
(44806118)
9
17
5.54
3.56
2.4
1.4
—
—
—
0
0
(3021952) Alkaline phosphatase isoenzymes [Enzymatic activity/volume] in Serum or Plasma by Heat stability
8
13
6.41
3.54
1.4
1.1
—
—
—
0
0
(40763086) Leukocyte esterase [Presence] in Urine by Automated test strip
74
511
1.82
3.44
6.4
3.8
—
—
—
0
0
(3005772) Bilirubin.conjugated [Moles/volume] in Serum or Plasma
30
151
2.21
3.43
2.3
3.3
umol/l
10.1
8.9
0.15
25
132
(3028271) Lactate [Moles/volume] in Capillary blood
9
18
5.23
3.42
3.0
1.4
mmol/l
1.8
1.6
—
9
18
(3027456) Digoxin [Moles/volume] in Serum or Plasma
10
27
3.88
3.41
3.9
2.5
nmol/l
0.8
0.8
—
5
19
(40760888) Immunoglobulin light chains.free panel - Serum
10
27
3.88
3.41
3.9
3.8
—
—
—
0
0
(3044927) Protein electrophoresis panel - Urine
7
10
7.26
3.40
1.3
1.2
—
—
—
0
0
(3011960) Natriuretic peptide B [Mass/volume] in Serum or Plasma
24
110
2.39
3.39
3.6
3.4
ng/l
471.6
193.8
1.11
24
98
(3024928) Oxygen saturation in Venous blood
9
19
4.95
3.29
5.1
4.1
—
—
—
0
0
(3005702) Mycobacterium sp identified in Specimen by Organism specific culture
10
28
3.74
3.25
1.8
1.3
—
—
—
0
0
(3021788) Differential panel - Synovial fluid
9
21
4.47
3.04
1.4
1.5
—
—
—
0
0
(3037121) Protein [Mass/volume] in Urine
12
40
3.16
3.04
3.2
3.3
g/l
0.3
0.2
—
5
15
(3022145) Colonoscopy Study observation
29
152
2.11
2.99
1.2
1.2
—
—
—
0
0
(3019902) Methicillin resistant Staphylococcus aureus [Presence] in Specimen by Organism specific culture
27
139
2.13
2.91
5.6
3.4
—
—
—
0
0
(3020460) C reactive protein [Mass/volume] in Serum or Plasma
145
1274
2.32
2.82
35.4
14.8
mg/l
26.5
24.4
0.37
137
1021
(3045414) Leukocytes [Presence] in Urine
12
42
3.01
2.81
2.5
1.7
—
—
—
0
0
(3044640) Blood type and Crossmatch panel - Blood
59
401
1.74
2.77
3.6
2.5
—
—
—
0
0
(3019601) Blood group antibody investigation [Interpretation] in Plasma or RBC
5
6
8.55
2.77
1.4
1.3
—
—
—
0
0
(3045788) Cell count panel - Pleural fluid
5
6
8.55
2.77
1.4
1.0
—
—
—
0
0
(3014959) Toxoplasma gondii IgG Ab [Units/volume] in Serum
6
10
6.18
2.72
2.0
2.6
—
—
—
0
0
(3027529) Toxoplasma gondii IgM Ab [Units/volume] in Serum
6
10
6.18
2.72
1.0
1.3
—
—
—
0
0
(3041642) Human coronavirus 229E RNA [Presence] in Specimen by NAA with probe detection
7
15
4.82
2.62
2.7
2.2
—
—
—
0
0
(3019230) Fractional oxyhemoglobin in Venous blood
7
15
4.82
2.62
5.3
1.8
%
72.1
64.1
—
7
15
(3009595) Pneumocystis jiroveci DNA [Presence] in Specimen by NAA with probe detection
7
15
4.82
2.62
2.1
1.5
—
—
—
0
0
(3038546) Human coronavirus OC43 RNA [Presence] in Specimen by NAA with probe detection
7
15
4.82
2.62
2.7
2.2
—
—
—
0
0
(3040359) Human coronavirus NL63 RNA [Presence] in Specimen by NAA with probe detection
7
15
4.82
2.62
2.7
2.2
—
—
—
0
0
(46235355) HIV 1 and 2 tests - Meaningful Use set
29
161
1.98
2.57
2.5
1.7
—
—
—
0
0
(4062490)
6
11
5.62
2.56
1.3
1.4
—
—
—
0
0
(3035637) Corticotropin [Mass/volume] in Plasma
6
11
5.62
2.56
1.0
1.5
—
—
—
0
0
(3042596) Human coronavirus RNA [Presence] in Specimen by NAA with probe detection
7
16
4.52
2.50
1.4
1.4
—
—
—
0
0
(46236098) ABO and Rh group [Type] in Blood by Confirmatory method
47
309
1.73
2.45
3.5
2.4
—
—
—
0
0
(3013512) EKG study
60
422
1.67
2.44
5.6
3.5
—
—
—
0
0
(3032699) Streptococcus pneumoniae DNA [Presence] in Specimen by NAA with probe detection
6
12
5.15
2.42
1.3
1.2
—
—
—
0
0
(4306422)
6
12
5.15
2.42
1.5
1.6
—
—
—
0
0
(3033658) Prothrombin time (PT) actual/Normal
46
302
1.73
2.40
7.7
3.7
%
89.2
89.6
0.03
46
295
(3025023) Rhinovirus RNA [Presence] in Specimen by NAA with probe detection
7
17
4.25
2.38
1.9
2.1
—
—
—
0
0
(3044889) 12 lead EKG panel
112
926
1.68
2.38
5.9
4.1
—
—
—
0
0
(3021879) Hepatitis B virus core Ab [Presence] in Serum
18
86
2.23
2.33
1.8
1.5
—
—
—
0
0
(3019050) Tissue transglutaminase IgA Ab [Units/volume] in Serum
37
231
1.78
2.29
1.3
1.2
u/ml
0.6
2.0
0.75
13
57
(3016881) Enterovirus RNA [Presence] in Specimen by NAA with probe detection
7
18
4.01
2.28
1.9
2.0
—
—
—
0
0
(40768797) Stomach Pathology biopsy report
32
192
1.83
2.25
1.3
1.2
—
—
—
0
0
(3014162) Mycobacterium tuberculosis DNA [Presence] in Specimen by NAA with probe detection
12
48
2.62
2.24
2.4
3.2
—
—
—
0
0
(40764127) Haemophilus influenzae DNA [Presence] in Specimen by NAA with probe detection
5
9
5.69
2.23
1.4
1.1
—
—
—
0
0
(3026389) Candida sp identified in Specimen by Organism specific culture
5
9
5.69
2.23
1.4
1.1
—
—
—
0
0
(3009035) Cobalamin (Vitamin B12) [Moles/volume] in Serum or Plasma
41
267
1.72
2.19
2.0
1.8
pmol/l
499.3
427.6
0.63
35
222
(3023150) Myeloperoxidase Ab [Units/volume] in Serum
8
25
3.31
2.12
1.0
1.9
—
—
—
0
0
(3037875) Bordetella parapertussis DNA [Presence] in Specimen by NAA with probe detection
5
10
5.12
2.08
1.4
1.1
—
—
—
0
0
(3033705) Calcium.ionized [Moles/volume] in Venous blood
6
15
4.11
2.06
4.3
2.1
—
—
—
0
0
(3027544) Mycobacterium sp identified in Sputum by Organism specific culture
6
15
4.11
2.06
4.5
3.5
—
—
—
0
0
(3015816) F5 gene p.Arg506Gln [Presence] in Blood or Tissue by Molecular genetics method
6
15
4.11
2.06
1.5
1.3
—
—
—
0
0
(3045783) Sodium and Potassium panel [Moles/volume] - Serum or Plasma
29
174
1.81
2.04
22.6
7.4
—
—
—
0
0
(3048929) Epstein Barr virus Ab [Presence] in Serum
9
32
2.92
2.03
1.1
1.2
—
—
—
0
0
(3008486) Thyroxine (T4) free [Moles/volume] in Serum or Plasma
109
916
1.58
1.97
5.0
3.7
pmol/l
15.2
14.9
0.58
98
815
(3015635) Cytomegalovirus IgM Ab [Units/volume] in Serum or Plasma
8
27
3.06
1.96
3.6
1.5
—
—
—
0
0
(3017918) Cytomegalovirus IgG Ab [Titer] in Serum or Plasma
8
27
3.06
1.96
3.8
1.5
—
—
—
0
0
(3007844) Epstein Barr virus capsid IgM Ab [Units/volume] in Serum by Immunoassay
7
22
3.28
1.90
1.1
1.3
—
—
—
0
0
(3051714) Fibrin D-dimer FEU [Mass/volume] in Platelet poor plasma
40
269
1.65
1.89
3.7
1.7
mg/l
1.4
1.3
0.10
31
211
(3009201) Thyrotropin [Units/volume] in Serum or Plasma
129
1135
1.67
1.86
5.9
4.5
mu/l
2.0
1.9
0.19
123
1007
(3044941) Cell count panel - Synovial fluid
6
17
3.62
1.85
1.7
1.6
—
—
—
0
0
(40764126) Parainfluenza virus RNA [Presence] in Specimen by NAA with probe detection
5
12
4.26
1.83
1.4
1.4
—
—
—
0
0
(3000093) Morphology [Interpretation] in Blood Narrative
5
12
4.26
1.83
1.0
1.0
—
—
—
0
0
(3014765) Yersinia sp identified in Stool by Organism specific culture
9
35
2.66
1.83
1.7
1.2
—
—
—
0
0
(3017895) Helicobacter pylori Ab [Units/volume] in Serum
9
35
2.66
1.83
1.7
1.5
—
—
—
0
0
(40762366) Oxygen capacity [Volume Fraction] in Arterial blood
14
67
2.19
1.82
25.4
16.2
—
—
—
0
0
(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection
82
656
1.51
1.80
2.8
2.6
—
—
—
0
0
(3002434) Lupus erythematosus deoxynucleoproteins IgG Ab [Units/volume] in Serum by Immunoassay
10
41
2.53
1.79
1.4
1.8
—
—
—
0
0
(3006418) Campylobacter sp identified in Tissue by Organism specific culture
9
36
2.59
1.77
1.7
1.2
—
—
—
0
0
(42529406) Shigella sp [Presence] in Stool by Culture
9
36
2.59
1.77
1.7
1.2
—
—
—
0
0
(3032155) Metanephrine Free [Moles/volume] in Serum or Plasma
6
18
3.42
1.76
1.3
1.2
—
—
—
0
0
(40761536) Microorganisms panel - Urine sediment
19
104
1.94
1.76
5.8
3.9
—
—
—
0
0
(3022313) Gas panel - Capillary blood
14
68
2.16
1.76
5.0
2.7
—
—
—
0
0
(40769539) Bacteria identified based on 16S rRNA gene [Identifier] in Specimen by Sequencing
8
30
2.75
1.75
1.3
1.6
—
—
—
0
0
(3045424) Erythrocytes [Presence] in Urine
5
13
3.93
1.73
1.0
1.2
—
—
—
0
0
(3041096) Erythrocytes [Presence] in Urine by Automated
49
355
1.55
1.69
5.1
3.1
—
—
—
0
0
(42868544) Hantavirus puumala IgM Ab [Presence] in Serum or Plasma by Immunofluorescence
6
19
3.24
1.67
1.0
1.0
—
—
—
0
0
(3046524) Influenza virus A Ag [Presence] in Nasopharynx by Immunoassay
7
25
2.88
1.67
1.4
1.3
—
—
—
0
0
(3043362) Influenza virus B Ag [Presence] in Nasopharynx by Immunoassay
7
25
2.88
1.67
1.4
1.3
—
—
—
0
0
(3038515) Glucose [Moles/volume] in Venous blood
7
25
2.88
1.67
4.4
2.2
mmol/l
6.7
7.9
—
7
25
(3016650) Hepatitis A virus Ab [Presence] in Serum
5
14
3.65
1.62
1.0
1.1
—
—
—
0
0
(3000494) Fungus identified in Specimen by Culture
26
162
1.72
1.62
1.7
1.7
—
—
—
0
0
(40761511) CBC panel - Blood by Automated count
145
1332
1.84
1.60
34.5
13.8
—
—
—
0
0
(3030905) Polymorphonuclear cells [#/volume] in Blood
6
20
3.07
1.59
3.3
2.5
e9/l
3.6
4.5
—
6
20
(3013327) Hepatitis A virus IgM Ab [Presence] in Serum
5
15
3.40
1.53
1.0
1.0
—
—
—
0
0
(3008037) Lactate [Moles/volume] in Venous blood
7
27
2.66
1.53
4.4
2.1
mmol/l
1.2
1.9
—
7
27
(3004716) Salmonella sp identified in Stool by Organism specific culture
11
52
2.20
1.48
1.5
1.4
—
—
—
0
0
(43054914) Glucose tolerance 2 hours panel - Serum or Plasma
19
111
1.81
1.47
1.4
1.4
—
—
—
0
0
(4035726)
19
111
1.81
1.47
1.4
1.4
—
—
—
0
0
(3009542) Hematocrit [Volume Fraction] of Blood
125
1115
1.53
1.46
32.9
15.7
%
38.0
39.8
0.83
72
756
(3045142) Bone marrow Pathology biopsy report
5
16
3.19
1.45
1.0
1.2
—
—
—
0
0
(3032035) Polymorphonuclear cells/100 leukocytes in Blood
6
22
2.79
1.45
3.5
3.5
%
53.3
56.3
—
6
22
(36031861) Influenza virus A and B and SARS-CoV-2 (COVID-19) and Respiratory syncytial virus RNA panel - Respiratory system specimen by NAA with probe detection
14
74
1.98
1.44
2.5
1.7
—
—
—
0
0
(3052851) Hemolysis interference index of Serum or Plasma
9
42
2.21
1.36
5.4
3.4
—
—
—
0
0
(3009340) Metanephrine [Moles/volume] in Serum or Plasma
5
18
2.83
1.29
1.4
1.3
nmol/l
—
—
—
0
0
(3013139) Helicobacter pylori Ag [Presence] in Stool
12
63
1.98
1.26
1.2
1.2
—
—
—
0
0
(4034850)
8
37
2.22
1.23
14.1
13.5
—
—
—
0
0
(3018559) Microscopic observation [Identifier] in Buccal smear by Cyto stain
5
19
2.68
1.22
1.0
1.2
—
—
—
0
0
(3037756) Immunofixation for Serum or Plasma
8
38
2.16
1.20
1.3
1.2
—
—
—
0
0
(3024891) Influenza virus A+B Ag [Presence] in Specimen
6
26
2.36
1.20
1.3
1.1
—
—
—
0
0
(44816559) Phosphatidylethanol [Mass/volume] in Blood
6
26
2.36
1.20
1.2
1.2
—
—
—
0
0
(36033641) SARS-CoV-2 (COVID-19) Ag [Presence] in Upper respiratory specimen by Rapid immunoassay
5
20
2.55
1.16
2.0
1.7
—
—
—
0
0
(3016251) Hemoglobin.gastrointestinal [Presence] in Stool
12
69
1.80
0.99
1.8
2.3
—
—
—
0
0
(4010399)
17
109
1.63
0.98
1.6
1.4
—
—
—
0
0
(37019628) Gastrointestinal bacterial pathogens panel - Stool by NAA with probe detection
6
27
2.27
0.94
2.0
1.4
—
—
—
0
0
(46237023) Hepatitis B virus core and surface Ab and surface Ag panel - Serum
6
28
2.19
0.92
2.7
1.3
—
—
—
0
0
(3003327) Ova and parasites identified in Stool by Light microscopy
6
28
2.19
0.92
1.2
1.4
—
—
—
0
0
(40768443) Skin Pathology biopsy report
11
64
1.77
0.88
1.0
1.3
—
—
—
0
0
(3001308) Cholesterol in LDL [Moles/volume] in Serum or Plasma
138
1302
1.40
0.78
6.9
5.0
mmol/l
2.5
2.7
2.51
131
1173
(3004410) Hemoglobin A1c/Hemoglobin.total in Blood
130
1216
1.35
0.77
10.1
5.8
mmol/mol
44.1
40.0
3.37
124
1118
(3019225) pH of Specimen
18
125
1.50
0.76
6.5
3.6
—
—
—
0
0
(3046870) Tissue transglutaminase IgG Ab [Units/volume] in Serum
7
39
1.83
0.73
1.0
1.0
—
—
—
0
0
(3044254) Respiratory syncytial virus RNA [Presence] in Specimen by NAA with probe detection
7
39
1.83
0.73
2.1
2.1
—
—
—
0
0
(3019900) Cholesterol [Moles/volume] in Serum or Plasma
135
1273
1.36
0.72
6.3
4.5
mmol/l
4.3
4.6
1.87
127
1158
(3000330) Specific gravity of Urine by Test strip
9
58
1.58
0.71
6.9
3.1
—
—
—
0
0
(46235759) Influenza virus B RNA [Presence] in Nasopharynx by NAA with probe detection
7
41
1.74
0.71
2.6
2.5
—
—
—
0
0
(3049717) Cytology report of Urine Cyto stain
11
69
1.64
0.70
1.6
2.8
—
—
—
0
0
(3023602) Cholesterol in HDL [Moles/volume] in Serum or Plasma
134
1266
1.34
0.68
6.2
4.4
mmol/l
1.3
1.4
3.97
126
1140
(3036086) Jo-1 extractable nuclear Ab [Units/volume] in Serum by Immunoassay
5
30
1.69
0.62
1.4
1.3
—
—
—
0
0
(3023081) Carboxyhemoglobin/Hemoglobin.total in Blood
8
51
1.60
0.61
4.1
13.9
%
1.3
1.7
—
8
46
(3029511) Human papilloma virus DNA [Presence] in Specimen by NAA with probe detection
0
23
0.00
0.59
0.0
1.5
—
—
—
0
0
(3048773) Triglyceride [Moles/volume] in Serum or Plasma --fasting
129
1226
1.26
0.52
5.8
4.0
mmol/l
1.8
1.3
7.44
120
1098
(3024135) Streptococcus.beta-hemolytic [Presence] in Throat by Organism specific culture
20
156
1.32
0.48
1.6
1.4
—
—
—
0
0
(3019832) Treponema pallidum Ab [Presence] in Serum
7
51
1.39
0.44
3.7
1.5
—
—
—
0
0
(36660697) Celiac disease serology panel - Serum
11
78
1.44
0.44
1.0
1.2
—
—
—
0
0
(1761482) Bacteria [#/volume] in Urine by Culture
5
31
1.63
0.43
8.8
3.5
—
—
—
0
0
(3013603) Prostate specific Ag [Mass/volume] in Serum or Plasma
71
648
1.17
0.41
4.2
5.3
ug/l
2.6
2.8
0.12
63
579
(3023351) European house dust mite IgE Ab [Units/volume] in Serum
0
17
0.00
0.41
0.0
1.1
—
1.7
—
0
7
(40768804) Tissue Pathology biopsy report
57
514
1.17
0.38
1.8
2.1
—
—
—
0
0
(3003694) ABO and Rh group [Type] in Blood
38
331
1.19
0.38
1.6
1.3
—
—
—
0
0
(3022621) pH of Urine by Test strip
7
100
0.69
0.31
3.0
3.0
—
—
—
0
0
(3018251) Fasting glucose [Moles/volume] in Serum or Plasma
130
1261
1.16
0.26
6.3
4.8
mmol/l
6.5
6.0
2.69
121
1141
(1761868) Lipid panel - Serum or Plasma
38
420
0.88
0.26
3.6
2.8
—
—
—
0
0
(3016888) Borrelia burgdorferi IgG Ab [Units/volume] in Serum
10
78
1.30
0.25
1.1
1.3
—
30.6
—
0
9
(3003785) Carcinoembryonic Ag [Mass/volume] in Serum or Plasma
18
154
1.19
0.22
4.6
4.7
ug/l
3.2
73.2
0.79
13
132
(40766048) U1 small nuclear ribonucleoprotein 70kD Ab [Units/volume] in Serum by Immunoassay
0
11
0.00
0.21
0.0
1.2
—
—
—
0
0
(3041145) Herpes simplex virus IgM Ab [Presence] in Serum by Immunoassay
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
(3041423) Sjogrens syndrome-A extractable nuclear 60kD Ab [Units/volume] in Serum
0
12
0.00
0.21
0.0
1.1
—
—
—
0
0
(3006442) Creatine [Moles/volume] in Serum or Plasma
0
12
0.00
0.21
0.0
1.2
—
—
—
0
0
(3016701) Glucose [Moles/volume] in Serum or Plasma --2 hours post dose glucose
0
12
0.00
0.21
0.0
1.1
—
7.5
—
0
7
(3049506) Microalbumin [Mass/time] in Urine collected for unspecified duration
0
12
0.00
0.21
0.0
1.8
—
—
—
0
0
(42529200) Cancer Ag 15-3 [Units/volume] in Serum or Plasma by Immunoassay
0
13
0.00
0.21
0.0
4.0
—
56.9
—
0
13
(3008401) Mugwort IgE Ab [Units/volume] in Serum
0
13
0.00
0.21
0.0
1.1
—
1.5
—
0
5
(3003888) Timothy IgE Ab [Units/volume] in Serum
0
14
0.00
0.20
0.0
1.1
—
6.4
—
0
6
(3007930) Methemoglobin/Hemoglobin.total in Blood
6
51
1.18
0.19
2.7
14.0
%
0.7
0.9
—
6
45
(3008230) Borrelia burgdorferi IgM Ab [Units/volume] in Serum
11
92
1.21
0.16
2.1
2.3
—
5.4
—
0
6
(3018006) Microscopic observation [Identifier] in Cervix by Cyto stain.thin prep
13
112
1.17
0.15
1.5
1.4
—
—
—
0
0
(3003338) MCHC [Mass/volume]
107
1043
1.08
0.13
49.7
20.0
g/l
329.3
332.4
2.69
107
1037
(3001784) Prostate Specific Ag Free/Prostate specific Ag.total in Serum or Plasma
51
530
0.94
0.09
3.9
4.7
%
22.2
21.1
0.22
29
281
(3022914) Cancer Ag 19-9 [Units/volume] in Serum or Plasma
7
63
1.12
0.08
2.3
3.6
u/ml
15.1
1867.2
—
7
52
(42868674) Cholesterol in HDL/Cholesterol.total [Molar ratio] in Serum or Plasma
19
180
1.06
0.04
5.7
4.6
%
29.4
31.9
0.49
14
118
(40764999) Glomerular filtration rate/1.73 sq M.predicted [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (CKD-EPI)
122
1210
1.03
0.03
32.9
13.9
ml/min/173m2
61.6
77.0
7.85
114
1016
(3000492) Spirometry study
12
112
1.08
0.03
1.3
1.4
—
—
—
0
0
(3002256) Pathology report gross observation
17
174
0.97
0.00
1.3
1.2
—
—
—
0
0
(3042975) Streptococcus sp identified in Isolate by Organism specific culture
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(4211845)
0
5
0.00
0.00
0.0
7.4
—
—
—
0
0
(3008364) Apolipoprotein A-I [Mass/volume] in Serum or Plasma
0
9
0.00
0.00
0.0
1.7
—
—
—
0
0
(3050129) First trimester maternal screen panel - Serum or Plasma
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
(3022058) Hepatitis B virus DNA [Presence] in Serum or Plasma by NAA with probe detection
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
(4015189)
0
5
0.00
0.00
0.0
4.0
—
—
—
0
0
(3051593) INR in Capillary blood by Coagulation assay
0
5
0.00
0.00
0.0
17.0
—
—
—
0
0
(3004915) Chlamydophila pneumoniae IgA Ab [Units/volume] in Serum
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3011544) Albumin [Mass/volume] in Pleural fluid
0
5
0.00
0.00
0.0
1.0
—
18.3
—
0
5
(3035933) Granulocytes/100 leukocytes in Blood
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3015076) Soybean IgE Ab [Units/volume] in Serum
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3032773) Endomysium IgG Ab [Titer] in Serum
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
(3037692) Legionella sp identified in Specimen by Organism specific culture
0
9
0.00
0.00
0.0
1.2
—
—
—
0
0
(3003191) Choriogonadotropin (pregnancy test) [Presence] in Serum or Plasma
0
8
0.00
0.00
0.0
1.1
—
—
—
0
0
(42868415) European tick borne encephalitis virus IgM Ab [Presence] in Cerebral spinal fluid by Immunoassay
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
(40765096) Chromosome analysis panel by Banding
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3011831) Apolipoprotein B/Apolipoprotein A-I [Percentile]
0
8
0.00
0.00
0.0
1.6
—
—
—
0
0
(3008536) Aspergillus sp Ab [Presence] in Serum
0
9
0.00
0.00
0.0
1.4
—
—
—
0
0
(3020717) Zinc [Moles/volume] in Serum or Plasma
0
9
0.00
0.00
0.0
1.3
—
27.9
—
0
9
(3000081) cloZAPine [Moles/volume] in Serum or Plasma
0
6
0.00
0.00
0.0
7.0
—
863.0
—
0
6
(3002148) Methylenedioxymethamphetamine [Presence] in Urine by Screen method
0
6
0.00
0.00
0.0
2.8
—
—
—
0
0
(3002823) Mycoplasma pneumoniae IgG Ab [Units/volume] in Cerebral spinal fluid
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
(21492888) Glucose tolerance 2 hours gestational panel - Serum or Plasma
0
6
0.00
0.00
0.0
1.7
—
—
—
0
0
(3035320) C reactive protein [Mass/volume] in Body fluid
0
7
0.00
0.00
0.0
1.6
—
—
—
0
0
(3024666) Lithium, Blood [Moles/volume] in Serum or Plasma
0
6
0.00
0.00
0.0
9.3
—
0.7
—
0
6
(3000855) Microscopic observation [Identifier] in Vaginal fluid by Gram stain
0
7
0.00
0.00
0.0
1.4
—
—
—
0
0
(42869593) Oxyhemoglobin/Hemoglobin.total [Pure mass fraction] in Capillary blood
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
(3030429) Borrelia sp DNA [Identifier] in Specimen by NAA with probe detection
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
(3037677) Mycoplasma pneumoniae IgM Ab [Titer] in Cerebral spinal fluid
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
(44816752) ERBB2 gene copy number/nucleus in Tissue by FISH
0
7
0.00
0.00
0.0
1.3
—
—
—
0
0
(43055089) Myosin Ab [Presence] in Serum or Plasma by Immunoblot
0
6
0.00
0.00
0.0
1.3
—
—
—
0
0
(3000924) Streptococcus pyogenes [Presence] in Throat by Organism specific culture
0
7
0.00
0.00
0.0
1.3
—
—
—
0
0
(3008832) Norclozapine [Moles/volume] in Serum or Plasma
0
6
0.00
0.00
0.0
5.3
—
651.0
—
0
6
(3007821) Glucose [Moles/volume] in Serum or Plasma --baseline
0
6
0.00
0.00
0.0
1.0
—
9.9
—
0
6
(3016436) Lactate dehydrogenase [Enzymatic activity/volume] in Serum or Plasma
0
6
0.00
0.00
0.0
2.7
—
212.8
—
0
6
(3028679) Herpes simplex virus Ab [Presence] in Serum
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
(42868421) Varicella zoster virus IgM Ab [Presence] in Cerebral spinal fluid by Immunoassay
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
(42869547) Procollagen type III.N-terminal propeptide [Mass/volume] in Serum
0
6
0.00
0.00
0.0
1.0
—
8.1
—
0
6
(40761849) Varicella zoster virus IgG Ab [Units/volume] in Cerebral spinal fluid by Immunoassay
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
(3044212) Herpes simplex virus 1+2 IgM Ab [Presence] in Cerebral spinal fluid
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
(3027953) Aldolase [Enzymatic activity/volume] in Serum or Plasma
0
6
0.00
0.00
0.0
1.2
—
5.3
—
0
6
(43534045) MCM6 gene c.-13910C>T and -13915T>G [Identifier] in Blood or Tissue by Molecular genetics method Nominal
5
51
0.98
0.00
1.4
1.0
—
—
—
0
0
(3045683) HLA typing for celiac disease panel - Blood or Tissue
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
(1617658) Protocol used for examination of sentinel lymph nodes
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint E4_HYPERURI and mortality.

Females

Parameter HR [95% CI] p-value
E4_HYPERURI 2.552 [1.94, 3.35] < 0.001
Birth year 0.993 [0.98, 1.0] 0.157

During the follow-up period (1.1.1998 — 31.12.2019), 188 out of 407 females with E4_HYPERURI died.

Males

Parameter HR [95% CI] p-value
E4_HYPERURI 2.743 [1.91, 3.95] < 0.001
Birth year 0.985 [0.98, 0.99] 0.002

During the follow-up period (1.1.1998 — 31.12.2019), 181 out of 494 males with E4_HYPERURI died.

Mortality risk

Mortality risk for people of age

years, who have E4_HYPERURI.

N-year risk Females Males
1 0.153% 0.478%
5 1.103% 2.974%
10 3.035% 7.543%
15 5.976% 13.46%
20 10.95% 22.07%

Relationships between endpoints

Index endpoint: E4_HYPERURI – Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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