Effects of air pressure and water pressure

ST19_EFFEC_AIR_PRESSURE_WATER_PRESSURE

No definition available.

Endpoint definition

↥

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps	FinnGen
Phenotype data	519972
1. Apply sex-specific rule None	519972
2. Check conditions None	519972
3. Check pre-conditions, main-only, mode, registry filters Registry filters: Hospital discharge: ICD-10 — T70 Cause of death: ICD-10 — T70 2 out of 7 registries used, show all original rules.	192
4. Check minimum number of events None	192
5. Include endpoints None	192
6. Filter based on genotype QC (FinnGen only)	188

Control definitions (FinnGen only)

Control exclude: ST19_OTHER_UNSPE_EFFEC_EXTER_CAUSES

Extra metadata

Level in the ICD hierarchy: 3
First used in FinnGen datafreeze: DF4
Parent code in ICD-10: T6[6-9]|T7[0-8]
Name in latin: Effectus pressionis aeris et aquae

NAME	ST19_EFFEC_AIR_PRESSURE_WATER_PRESSURE
CONTROL_EXCLUDE	ST19_OTHER_UNSPE_EFFEC_EXTER_CAUSES
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX
INCLUDE
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10	T70
HD_ICD_9
HD_ICD_8
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10	T70
COD_ICD_9
COD_ICD_8
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

Similar endpoints

↥

List of similar endpoints to Effects of air pressure and water pressure based on the number of shared cases.

Similar with more cases:

Similar with less cases:

None

Case counts by codes

↥

FinnGen case counts by registry codes:

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

	All	Female	Male
Number of individuals	188	69	119
Unadjusted period prevalence (%)	0.04	0.02	0.05
Median age at first event (years)	41.31	37.68	43.41

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log₁₀(p-value) ≥ 6.

Matched cohort

Matched cases
192: Matched controls
1920

Code

Vocabulary

Description

Odds Ratio

-log₁₀(p)

N matched cases

N matched controls

T70.0

ICD-10 Finland

Otitic barotrauma

2575.2

129.9

111

T70.3

ICD-10 Finland

Caisson disease [decompression sickness]

+∞

52.5

W94

ICD-10 Finland

Exposure to high and low air pressure and changes in air pressure

+∞

34.4

W16

ICD-10 Finland

Diving or jumping into water causing injury other than drowning or submersion

185.4

16.8

T70.2

ICD-10 Finland

Other and unspecified effects of high altitude

+∞

15.8

X59

ICD-10 Finland

Exposure to unspecified factor

3.6

14.0

222

T70.8

ICD-10 Finland

Other effects of air pressure and water pressure

+∞

9.4

X58

ICD-10 Finland

Exposure to other specified factors

3.2

9.4

170

C01CA24

ATC

epinephrine; parenteral

4.3

7.8

WX750

NOMESCO Finland

Hyperbaric oxygen therapy

+∞

7.3

DFF00

NOMESCO Finland

Pure tone audiometry

3.4

6.7

T70.1

ICD-10 Finland

Sinus barotrauma

+∞

6.3

LabWAS

↥

N Cases

N Controls

-log₁₀(p)

cases

controls

cases

controls

unit

-log₁₀(p)

N cases

N controls

(3037467) Urinalysis macro (dipstick) panel - Urine

130

982

2.00

4.78

3.7

—

(3016431) Calcium.ionized [Moles/volume] adjusted to pH 7.4 in Serum or Plasma

596

1.88

4.37

6.5

7.9

1.22

1.21

mmol/l

0.22

502

(1002224) Polysomnography panel

100

2.48

3.59

1.1

—

(3019800) Troponin T.cardiac [Mass/volume] in Serum or Plasma

501

1.66

2.79

2.3

3.0

13.94

39.85

ng/l

2.05

297

(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection

142

1196

1.72

2.74

3.3

3.4

—

(3021347) Calcium.ionized [Moles/volume] in Serum or Plasma

548

1.64

2.73

6.8

7.0

1.22

1.21

mmol/l

0.47

513

(3000494) Fungus identified in Specimen by Culture

164

1.98

2.73

1.5

1.6

—

(3037522) Nuclear Ab [Titer] in Serum

211

1.87

2.67

1.6

1.4

286.67

361.14

titre

—

(3022217) INR in Platelet poor plasma by Coagulation assay

576

1.60

2.50

13.1

10.0

1.07

1.16

inr

1.15

177

(3000991) Gas panel - Venous blood

111

2.11

2.47

9.8

8.3

—

(3013826) Glucose [Moles/volume] in Serum or Plasma

105

833

1.57

2.47

5.6

5.0

6.55

6.61

mmol/l

0.08

100

770

(3044889) 12 lead EKG panel

123

1019

1.58

2.34

3.3

3.2

—

(3024928) Oxygen saturation in Venous blood

3.32

2.34

1.4

2.3

—

(3018171) Choriogonadotropin [Units/volume] in Serum or Plasma

2.51

2.25

2.8

2.4

12239.92

399.87

u/l

—

(40766048) U1 small nuclear ribonucleoprotein 70kD Ab [Units/volume] in Serum by Immunoassay

5.67

2.22

1.2

1.3

—

(3038026) Centromere Ab [Units/volume] in Serum

5.67

2.22

1.2

1.3

—

(3015736) pH of Urine

600

1.54

2.18

2.5

2.8

6.17

5.81

0.51

(3016018) Differential panel - Cerebral spinal fluid

5.10

2.08

1.2

—

(3041423) Sjogrens syndrome-A extractable nuclear 60kD Ab [Units/volume] in Serum

5.10

2.08

1.2

—

(3013721) Aspartate aminotransferase [Enzymatic activity/volume] in Serum or Plasma

550

1.53

2.07

3.4

3.2

32.92

33.92

u/l

0.06

522

(3000492) Spirometry study

180

1.79

2.07

1.7

1.4

—

(44816559) Phosphatidylethanol [Mass/volume] in Blood

2.44

1.99

1.3

1.2

—

(3011371) Neisseria gonorrhoeae DNA [Presence] in Specimen by NAA with probe detection

2.07

1.92

1.5

2.0

—

(3039443) Prostate specific Ag panel - Serum or Plasma

2.35

1.85

1.6

1.5

—

(3044640) Blood type and Crossmatch panel - Blood

446

1.50

1.78

2.9

2.4

—

(46236098) ABO and Rh group [Type] in Blood by Confirmatory method

342

1.54

1.73

2.8

2.4

—

(3011648) Oxygen content in Venous blood

3.92

1.72

1.4

1.3

11.26

13.49

—

(3020460) C reactive protein [Mass/volume] in Serum or Plasma

170

1565

1.75

1.70

14.2

12.0

22.53

21.76

mg/l

0.10

141

1194

(3005013) Prostate Specific Ag Free [Mass/volume] in Serum or Plasma

326

1.54

1.69

2.4

2.5

0.60

0.73

ug/l

0.42

180

(42529201) Cancer Ag 19-9 [Units/volume] in Serum or Plasma by Immunoassay

2.87

1.66

7.7

5.6

26.86

963.75

u/ml

—

(36660697) Celiac disease serology panel - Serum

106

1.88

1.66

1.1

1.2

—

(40766800) Mycobacterium tuberculosis stimulated gamma interferon release by CD4+ T-cells [Units/volume] corrected for background in Blood

3.64

1.62

1.2

1.4

—

(3041096) Erythrocytes [Presence] in Urine by Automated

420

1.47

1.57

2.7

2.4

—

(3013512) EKG study

349

1.50

1.57

3.4

3.3

—

(3002109) Cholesterol in LDL/Cholesterol in HDL [Mass Ratio] in Serum or Plasma

222

1.59

1.52

1.8

1.7

—

(3036086) Jo-1 extractable nuclear Ab [Units/volume] in Serum by Immunoassay

2.50

1.50

1.2

—

(43534045) MCM6 gene c.-13910C>T and -13915T>G [Identifier] in Blood or Tissue by Molecular genetics method Nominal

1.95

1.49

1.2

1.0

—

(3027545) Mycoplasma pneumoniae Ab [Presence] in Serum by Immunoassay

2.18

1.47

1.3

1.2

—

(3035350) Ketones [Presence] in Urine by Test strip

726

1.39

1.45

3.0

0.00

0.01

estimate

0.50

145

(3004616) Nuclear Ab [Presence] in Serum

3.18

1.44

1.2

1.3

—

(44816844) Macroprolactin [Units/volume] in Serum or Plasma

2.78

1.44

1.0

1.3

—

(3008486) Thyroxine (T4) free [Moles/volume] in Serum or Plasma

125

1094

1.41

1.44

3.6

3.8

14.42

14.62

pmol/l

0.43

118

1029

(40762366) Oxygen capacity [Volume Fraction] in Arterial blood

2.07

1.41

11.9

18.6

—

(3044941) Cell count panel - Synovial fluid

2.99

1.36

1.2

—

(3021614) Rheumatoid factor [Units/volume] in Serum or Plasma

245

1.52

1.36

1.3

12.08

24.33

iu/ml

1.45

(3003510) Neisseria gonorrhoeae DNA [Presence] in Urine by NAA with probe detection

229

1.53

1.34

1.9

2.0

—

(3050238) Crystals [Presence] in Synovial fluid by Light microscopy

2.55

1.31

2.0

1.0

—

(3001019) Free T4 and TSH panel - Serum or Plasma

107

1.75

1.31

2.1

1.9

—

(3021337) Troponin I.cardiac [Mass/volume] in Serum or Plasma

240

1.51

1.28

2.9

74.46

216.01

ng/l

0.94

169

(40768804) Tissue Pathology biopsy report

566

1.37

1.27

2.0

1.9

—

(3021601) Nitrite [Presence] in Urine by Test strip

719

1.36

1.26

4.7

4.1

0.00

estimate

-0.00

138

(4094501) Cardiovascular stress test using bicycle ergometer

2.05

1.25

1.1

—

(40763086) Leukocyte esterase [Presence] in Urine by Automated test strip

558

1.37

1.25

2.9

—

(3025941) Bacteria identified in Stool by Culture

1.77

1.21

1.2

—

(3041942) Cyclic citrullinated peptide Ab [Units/volume] in Serum

244

1.48

1.18

1.4

1.2

1.01

4.26

u/ml

1.44

(3047007) Chlamydophila sp Ab [Presence] in Serum

2.10

1.16

1.3

1.2

—

(3044938) Influenza virus A RNA [Presence] in Specimen by NAA with probe detection

219

1.50

1.16

1.5

2.0

—

(3044491) Cholesterol non HDL [Mass/volume] in Serum or Plasma

160

1.57

1.16

1.6

1.4

—

(40764999) Glomerular filtration rate/1.73 sq M.predicted [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (CKD-EPI)

158

1464

1.45

1.14

13.4

10.6

89.11

89.99

ml/min/173m2

0.25

139

1195

(3006093) Chlamydia trachomatis DNA [Presence] in Specimen by NAA with probe detection

112

1.67

1.13

1.7

2.1

—

(3024950) Chlamydia trachomatis DNA [Presence] in Urine by NAA with probe detection

255

1.46

1.13

2.1

—

(3019902) Methicillin resistant Staphylococcus aureus [Presence] in Specimen by Organism specific culture

130

1.60

1.08

4.3

3.1

—

(3007164) IgA [Mass/volume] in Serum or Plasma

321

1.39

1.05

1.7

1.4

2.39

2.32

g/l

0.13

218

(3009261) Glucose [Presence] in Urine by Test strip

734

1.31

1.05

3.3

3.0

0.00

estimate

-0.00

134

(3022145) Colonoscopy Study observation

156

1.54

1.04

1.5

1.3

—

(3023368) Bacteria identified in Blood by Culture

340

1.38

1.04

5.0

4.6

—

(4035726) Immunohistochemistry procedure

115

1.62

1.04

1.6

1.4

—

(3051714) Fibrin D-dimer FEU [Mass/volume] in Platelet poor plasma

331

1.39

1.04

1.7

0.67

1.00

mg/l

1.07

250

(3010521) Mycoplasma pneumoniae IgM Ab [Presence] in Serum by Immunoassay

1.94

1.03

1.1

—

(3024889) Methemoglobin/Hemoglobin.total in Venous blood

1.94

1.03

1.7

2.5

0.63

0.72

—

(3001079) Blood group antibody screen [Presence] in Serum or Plasma

678

1.31

1.02

3.1

2.6

—

(3034770) Mitochondria Ab [Titer] in Serum

1.88

1.00

2.3

1.2

—

(3000924) Streptococcus pyogenes [Presence] in Throat by Organism specific culture

0.00

0.98

0.0

1.2

—

(21494755) Public health laboratory ask at order entry panel

282

1.39

0.95

1.6

1.4

—

(3004588) Protein electrophoresis panel - Serum or Plasma

1.76

0.95

1.2

2.3

—

(3001784) Prostate Specific Ag Free/Prostate specific Ag.total in Serum or Plasma

439

1.32

0.92

3.2

3.6

19.33

21.98

0.63

170

(3024135) Streptococcus.beta-hemolytic [Presence] in Throat by Organism specific culture

357

1.34

0.90

1.3

1.5

—

(36033641) SARS-CoV-2 (COVID-19) Ag [Presence] in Upper respiratory specimen by Rapid immunoassay

2.10

0.90

2.0

1.8

—

(3026008) Bacteria identified in Urine by Culture

294

1.36

0.89

2.5

2.4

—

(40761536) Microorganisms panel - Urine sediment

120

1.55

0.89

3.8

3.4

—

(3009201) Thyrotropin [Units/volume] in Serum or Plasma

146

1355

1.32

0.88

4.2

4.3

1.81

1.84

mu/l

0.12

140

1271

(3004119) Hemoglobin [Mass/volume] in Venous blood

1.76

0.88

1.6

3.8

133.27

133.75

g/l

0.02

(40766189) Gliadin peptide IgG Ab [Units/volume] in Serum by Immunoassay

1.85

0.87

1.0

1.1

—

3.57

—

(586526) SARS-CoV-2 (COVID-19) RNA [Presence] in Nasopharynx by NAA with probe detection

1.69

0.83

1.4

1.3

—

(3013527) Hepatitis B virus core IgM Ab [Presence] in Serum

1.90

0.82

1.5

1.3

—

(3002173) Hemoglobin [Mass/volume] in Arterial blood

106

1.56

0.82

13.4

14.3

123.63

125.02

g/l

0.10

101

(3028026) IgM [Mass/volume] in Serum or Plasma

106

1.56

0.82

2.0

1.6

1.02

1.48

g/l

0.88

100

(40763571) Iron/Transferrin [Ratio] in Serum or Plasma

174

1.43

0.81

1.7

2.2

23.81

23.46

0.02

157

(3037756) Immunofixation for Serum or Plasma

0.00

0.79

0.0

1.4

—

(3008909) Norovirus RNA [Presence] in Stool by NAA with probe detection

1.84

0.79

1.0

1.2

—

(3036481) Cortisol [Moles/volume] in Serum or Plasma

149

1.46

0.79

1.8

2.0

309.05

371.68

nmol/l

0.77

141

(3019225) pH of Specimen

107

1.54

0.79

4.5

5.1

—

(3000855) Microscopic observation [Identifier] in Vaginal fluid by Gram stain

0.00

0.79

0.0

1.4

—

(3014576) Chloride [Moles/volume] in Serum or Plasma

150

1.45

0.77

10.0

8.1

105.10

103.96

mmol/l

0.50

150

(3024891) Influenza virus A+B Ag [Presence] in Specimen

1.70

0.76

1.0

1.1

—

(40768797) Stomach Pathology biopsy report

186

1.40

0.75

1.1

1.2

—

(3003740) Influenza virus B Ag [Presence] in Specimen

1.87

0.74

1.0

1.2

—

(3002523) Influenza virus A Ag [Presence] in Specimen

1.87

0.74

1.0

1.2

—

(3029511) Human papilloma virus DNA [Presence] in Specimen by NAA with probe detection

1.87

0.74

1.7

1.4

—

(3049804) Myeloperoxidase IgG Ab [Units/volume] in Serum

1.78

0.72

2.4

1.1

—

(1175715) Chlamydophila pneumoniae IgM Ab [Presence] in Serum by Immunoassay

1.78

0.72

1.1

—

(3013707) Erythrocyte sedimentation rate by Westergren method

119

1091

1.24

0.71

5.3

3.8

9.89

8.92

mm/h

0.30

114

1020

(3045424) Erythrocytes [Presence] in Urine

1.95

0.71

1.2

1.7

—

(3014148) Varicella zoster virus Ab [Titer] in Serum

1.87

0.69

1.0

1.2

—

(3005322) IgE [Units/volume] in Serum or Plasma

1.53

0.69

1.4

1.3

56.63

143.82

u/ml

1.91

(3019050) Tissue transglutaminase IgA Ab [Units/volume] in Serum

344

1.28

0.68

1.4

1.3

0.89

u/ml

—

104

(3033319) Streptococcus pyogenes Ag [Presence] in Throat

244

1.32

0.67

1.5

1.4

—

(3044290) Cell count panel - Cerebral spinal fluid

1.81

0.66

1.2

1.6

—

(3012220) Varicella zoster virus IgM Ab [Presence] in Serum by Immunoassay

1.81

0.66

1.0

1.2

—

(3016502) Oxygen saturation in Arterial blood

112

1.47

0.66

13.2

13.7

97.29

96.11

0.88

107

(3043362) Influenza virus B Ag [Presence] in Nasopharynx by Immunoassay

1.74

0.64

1.0

1.3

—

(3046524) Influenza virus A Ag [Presence] in Nasopharynx by Immunoassay

1.74

0.64

1.0

1.3

—

(36031861) Influenza virus A and B and SARS-CoV-2 (COVID-19) and Respiratory syncytial virus RNA panel - Respiratory system specimen by NAA with probe detection

1.58

0.63

1.7

1.6

—

(3002434) Lupus erythematosus deoxynucleoproteins IgG Ab [Units/volume] in Serum by Immunoassay

1.62

0.63

1.6

2.8

—

(43054903) Holo-transcobalamin II [Moles/volume] in Serum

470

1.24

0.63

1.6

1.7

93.27

96.76

pmol/l

0.23

240

(40768793) Breast Pathology biopsy report

1.68

0.62

1.0

1.1

—

(3025023) Rhinovirus RNA [Presence] in Specimen by NAA with probe detection

0.00

0.60

0.0

2.3

—

(3028167) CD3+CD4+ (T4 helper) cells [#/volume] in Blood

0.00

0.60

0.0

2.2

—

567.71

—

(3016881) Enterovirus RNA [Presence] in Specimen by NAA with probe detection

0.00

0.58

0.0

2.2

—

(3026910) Gamma glutamyl transferase [Enzymatic activity/volume] in Serum or Plasma

130

1216

1.21

0.58

4.0

3.0

48.29

47.21

u/l

0.05

123

1161

(3038288) Influenza virus B RNA [Presence] in Specimen by NAA with probe detection

159

1.36

0.58

1.7

1.8

—

(3032836) C peptide [Moles/volume] in Serum or Plasma --fasting

1.74

0.58

1.7

1.5

0.66

0.89

nmol/l

—

(3006217) Methemoglobin/Hemoglobin.total in Arterial blood

1.54

0.57

16.8

10.8

0.62

0.68

0.25

(3043109) Cytology report of Tissue fine needle aspirate Cyto stain

1.64

0.56

1.3

1.2

—

(3018418) pH of Serum or Plasma

382

1.23

0.55

4.0

7.40

0.23

(3028653) Carboxyhemoglobin/Hemoglobin.total in Arterial blood

1.52

0.54

16.7

10.7

1.39

1.57

0.24

(3018095) Leukocytes [#/volume] in Urine

478

1.21

0.53

3.6

3.5

11.98

140.05

e6/l

0.91

321

(40761511) CBC panel - Blood by Automated count

173

1674

1.34

0.53

13.4

10.7

—

(3011397) Hemoglobin [Presence] in Urine by Test strip

328

1.24

0.52

2.6

3.2

—

(3051552) Clostridioides difficile toxin genes [Presence] in Stool by NAA with probe detection

101

1.42

0.51

2.0

1.6

—

(3004248) Sex hormone binding globulin [Moles/volume] in Serum or Plasma

101

1.42

0.51

2.1

1.9

37.07

34.23

nmol/l

0.33

101

(3021584) Pregnancy associated plasma protein A [Units/volume] in Serum or Plasma

110

0.62

0.50

2.4

1.5

—

(3048773) Triglyceride [Moles/volume] in Serum or Plasma --fasting

156

1497

1.22

0.47

3.7

3.6

1.31

1.34

mmol/l

0.13

147

1411

(3043924) Respiratory syncytial virus RNA [Identifier] in Specimen by NAA with probe detection

156

1.31

0.47

1.6

1.7

—

(3022621) pH of Urine by Test strip

0.59

0.47

3.2

1.9

—

(3016879) Cocaine [Presence] in Urine

103

1.39

0.46

2.6

1.4

—

(3044254) Respiratory syncytial virus RNA [Presence] in Specimen by NAA with probe detection

1.44

0.46

1.0

2.1

—

(3018006) Microscopic observation [Identifier] in Cervix by Cyto stain.thin prep

203

1.27

0.45

1.6

1.5

—

(3029937) Albumin [Presence] in Urine by Test strip

362

1.21

0.45

3.3

3.4

0.00

0.01

estimate

0.50

133

(3017895) Helicobacter pylori Ab [Units/volume] in Serum

1.39

0.44

1.9

1.6

—

(3027238) Thyroperoxidase Ab [Units/volume] in Serum or Plasma

113

1.36

0.44

1.7

1.2

46.59

139.44

iu/ml

—

(3003694) ABO and Rh group [Type] in Blood

487

1.18

0.44

1.5

—

(3013742) Prealbumin [Mass/volume] in Serum or Plasma

122

1.34

0.44

4.1

2.6

0.21

0.23

g/l

0.41

115

(3030905) Polymorphonuclear cells [#/volume] in Blood

1.58

0.42

3.2

3.7

2.89

4.68

e9/l

—

(3032035) Polymorphonuclear cells/100 leukocytes in Blood

1.58

0.42

5.2

3.8

51.00

57.22

—

(3019900) Cholesterol [Moles/volume] in Serum or Plasma

161

1555

1.22

0.42

4.1

3.9

4.71

4.73

mmol/l

0.08

152

1479

(3045783) Sodium and Potassium panel [Moles/volume] - Serum or Plasma

149

0.72

0.42

1.6

6.8

—

(3021952) Alkaline phosphatase isoenzymes [Enzymatic activity/volume] in Serum or Plasma by Heat stability

0.00

0.41

0.0

1.4

—

(3045414) Leukocytes [Presence] in Urine

1.35

0.41

1.8

1.6

—

(3025271) CD3-CD16+CD56+ (Natural killer) cells [#/volume] in Blood

0.00

0.40

0.0

2.2

—

0.21

—

(3001405) CD3+CD8+ (T8 suppressor) cells [#/volume] in Blood

0.00

0.40

0.0

2.2

—

625.31

—

(3014037) CD3+CD4+ (T4 helper) cells/100 cells in Blood

0.00

0.40

0.0

2.7

—

48.32

—

(40768443) Skin Pathology biopsy report

1.32

0.40

1.4

1.1

—

(43054914) Glucose tolerance 2 hours panel - Serum or Plasma

179

0.76

0.37

2.4

1.8

—

(3042936) Bacteria identified in Isolate by Culture

200

1.23

0.36

2.5

2.3

—

(3000764) Benzodiazepines [Presence] in Urine

109

1.31

0.34

2.6

1.4

—

(3029187) Natriuretic peptide.B prohormone N-Terminal [Mass/volume] in Serum or Plasma

306

1.18

0.33

1.6

2.5

263.26

643.64

ng/l

3.39

250

(3019250) Coagulation factor VIII activity actual/normal in Platelet poor plasma by Coagulation assay

1.29

0.32

2.5

2.1

181.67

189.23

—

(46235759) Influenza virus B RNA [Presence] in Nasopharynx by NAA with probe detection

1.36

0.31

1.0

2.5

—

(3003191) Choriogonadotropin (pregnancy test) [Presence] in Serum or Plasma

1.36

0.31

1.9

—

(3027944) Amphetamines [Presence] in Urine

111

1.28

0.31

2.6

1.4

—

(3028300) Cannabinoids [Presence] in Urine

111

1.28

0.31

2.6

1.4

—

(3027008) Opiates [Presence] in Urine

111

1.28

0.31

2.5

1.4

—

(3016251) Hemoglobin.gastrointestinal [Presence] in Stool

1.28

0.30

3.1

2.2

—

(46235355) HIV 1 and 2 tests - Meaningful Use set

405

1.15

0.30

2.2

1.9

—

(3001308) Cholesterol in LDL [Moles/volume] in Serum or Plasma

161

1568

1.17

0.29

4.5

4.3

2.79

2.86

mmol/l

0.55

151

1473

(3011288) Drugs identified in Urine by Screen method

1.24

0.27

4.9

1.4

—

(3023602) Cholesterol in HDL [Moles/volume] in Serum or Plasma

159

1549

1.15

0.27

4.2

3.9

1.44

1.40

mmol/l

0.59

150

1462

(3019309) Folate [Moles/volume] in Red Blood Cells

179

1.19

0.26

1.8

1.6

1051.41

1272.65

nmol/l

0.54

145

(3019832) Treponema pallidum Ab [Presence] in Serum

217

1.17

0.26

1.8

—

(1001926) Buprenorphine [Presence] in Urine by Screen method

0.71

0.24

4.3

1.4

—

(3030306) Epithelial cells.non-squamous [#/volume] in Urine by Automated count

221

0.84

0.24

3.2

2.5

1.10

0.90

e6/l

—

117

(3015816) F5 gene p.Arg506Gln [Presence] in Blood or Tissue by Molecular genetics method

1.36

0.23

1.0

1.2

—

(43055120) Cytomegalovirus DNA [Units/volume] (viral load) in Serum or Plasma by NAA with probe detection

1.32

0.23

5.6

4.2

—

749.29

—

(3004716) Salmonella sp identified in Stool by Organism specific culture

0.74

0.23

2.3

1.3

—

(3007930) Methemoglobin/Hemoglobin.total in Blood

1.26

0.22

5.0

18.2

0.80

0.89

—

(3018251) Fasting glucose [Moles/volume] in Serum or Plasma

150

1462

1.12

0.22

3.9

3.8

5.76

5.81

mmol/l

0.24

138

1368

(40758558) Short blood count panel - Blood

365

0.88

0.22

5.7

7.0

—

(3049717) Cytology report of Urine Cyto stain

1.23

0.22

2.4

2.6

—

(3023081) Carboxyhemoglobin/Hemoglobin.total in Blood

1.23

0.22

5.0

17.5

1.88

1.57

—

(3021879) Hepatitis B virus core Ab [Presence] in Serum

154

1.19

0.22

1.9

1.7

—

(3035933) Granulocytes/100 leukocytes in Blood

0.00

0.21

0.0

1.0

—

(3051651) Icteric interference index of Serum or Plasma

0.00

0.21

0.0

2.1

—

(21493195) Respiratory pathogens DNA and RNA tested for in Respiratory system specimen by NAA with probe detection

0.00

0.21

0.0

2.2

—

(37020957) Sapovirus genogroups I+II+IV+V RNA [Presence] in Stool by NAA with probe detection

0.00

0.21

0.0

1.5

—

(3035947) Staphylolysin Ab [Units/volume] in Serum

0.00

0.21

0.0

1.2

—

(3005156) Respiratory syncytial virus A RNA [Presence] in Specimen by NAA with probe detection

0.00

0.21

0.0

2.3

—

(4281824) Cell count and differential, peritoneal fluid

0.00

0.21

0.0

1.1

—

(3000108) Respiratory syncytial virus B RNA [Presence] in Specimen by NAA with probe detection

0.00

0.21

0.0

2.3

—

(44813793) Dust mix specific IgE antibody measurement

0.00

0.21

0.0

1.0

—

(37021247) Adenovirus 40+41 DNA [Presence] in Stool by NAA with probe detection

0.00

0.21

0.0

1.5

—

(40765089) Chromosome analysis panel - Blood by G-banded

0.00

0.21

0.0

1.0

—

(37020445) Astrovirus RNA [Presence] in Stool by NAA with probe detection

0.00

0.21

0.0

1.5

—

(40770918) von Willebrand factor (vWf).activity actual/normal in Platelet poor plasma by Immunoassay

0.00

0.21

0.0

2.2

—

116.90

—

(42869457) Rotavirus RNA [Identifier] in Stool by NAA with probe detection

0.00

0.21

0.0

1.5

—

(3017817) Protein [Mass] in Urine collected for unspecified duration

0.00

0.21

0.0

4.8

—

(3016914) Bacteria identified in Cerebral spinal fluid by Culture

0.00

0.21

0.0

1.3

—

(3034426) Prothrombin time (PT)

0.00

0.21

0.0

1.7

—

(3024666) Lithium [Moles/volume] in Serum or Plasma

0.00

0.21

0.0

9.6

—

0.55

—

(3029075) Extractable nuclear Ab panel - Serum

0.00

0.21

0.0

1.0

—

(3027544) Mycobacterium sp identified in Sputum by Organism specific culture

0.00

0.20

0.0

3.4

—

(40760847) Basement membrane Ab [Titer] in Serum by Immunofluorescence

0.00

0.20

0.0

1.2

—

(3051611) Lipemic interference index of Serum or Plasma

0.00

0.20

0.0

2.1

—

(3014162) Mycobacterium tuberculosis DNA [Presence] in Specimen by NAA with probe detection

1.23

0.20

1.3

2.5

—

(3013650) Neutrophils [#/volume] in Blood by Automated count

899

0.92

0.19

11.1

10.6

3.33

4.13

e9/l

2.93

799

(3017143) Hepatitis C virus Ab [Presence] in Serum

243

1.13

0.18

1.8

—

(3009214) Lutropin [Units/volume] in Serum or Plasma

1.13

0.17

1.6

1.5

3.74

5.89

u/l

—

(3022313) Gas panel - Capillary blood

1.12

0.17

1.1

3.1

—

(36032419) SARS-CoV-2 (COVID-19) Ag [Presence] in Upper respiratory specimen by Immunoassay

0.77

0.14

1.6

1.5

—

(3015377) Calcium [Moles/volume] in Serum or Plasma

424

1.08

0.13

2.4

3.8

2.36

mmol/l

0.24

384

(3029287) Urinalysis microscopic panel [#/volume] - Urine by Automated count

465

1.07

0.12

2.9

3.0

—

(3002582) Erythrocytes [#/volume] in Urine

407

1.07

0.11

3.0

408.31

42.35

e6/l

0.48

303

(3019284) Hepatitis B virus surface Ag [Presence] in Serum

319

1.08

0.11

2.1

1.7

—

(4200892) Spirometry reversibility

105

1.15

0.11

1.2

1.4

—

(3030467) Casts [#/volume] in Urine by Automated count

369

1.07

0.10

3.4

2.8

1.56

0.46

e6/l

0.34

267

(36304419) Bacteria [Presence] in Urine

369

1.07

0.10

3.4

2.7

—

(3012516) Albumin [Mass/volume] in Urine

330

0.93

0.10

3.8

3.5

32.47

264.42

mg/l

0.61

222

(3028707) Methadone [Presence] in Urine by Screen method

1.11

0.10

5.2

1.6

—

(3042194) Human metapneumovirus RNA [Presence] in Specimen by NAA with probe detection

1.04

0.09

1.2

1.9

—

(3025839) Triglyceride [Moles/volume] in Serum or Plasma

381

1.06

0.09

1.6

1.7

1.41

1.49

mmol/l

0.35

329

(3000515) Antithrombin actual/normal in Platelet poor plasma by Chromogenic method

1.09

0.09

2.2

1.8

95.50

90.64

—

(3003327) Ova and parasites identified in Stool by Light microscopy

1.09

0.09

1.5

—

(3000330) Specific gravity of Urine by Test strip

1.07

0.09

1.3

2.3

—

(3019198) Lymphocytes [#/volume] in Blood

799

1.05

0.08

7.0

6.5

1.85

1.94

e9/l

0.37

726

(3029879) Epithelial cells.squamous [#/volume] in Urine by Automated count

205

0.92

0.08

2.7

2.6

0.73

1.42

e6/l

—

102

(3019060) Gas panel - Arterial blood

1.05

0.08

3.9

11.3

—

(3009035) Cobalamin (Vitamin B12) [Moles/volume] in Serum or Plasma

225

1.08

0.08

1.7

514.28

463.92

pmol/l

0.35

202

(3048929) Epstein Barr virus Ab [Presence] in Serum

1.08

0.07

1.4

1.3

—

(3023024) Carbon dioxide [Partial pressure] in Capillary blood

1.07

0.07

1.1

3.2

4.93

5.09

kpa

—

(1761868) Lipid panel - Serum or Plasma

687

1.03

0.04

2.5

—

(3013115) Eosinophils [#/volume] in Blood

797

1.03

0.04

7.0

6.9

0.17

0.19

e9/l

0.63

722

(3004410) Hemoglobin A1c/Hemoglobin.total in Blood

138

1392

0.97

0.04

4.3

4.7

37.93

38.92

mmol/mol

0.71

127

1338

(3002256) Pathology report gross observation

169

0.94

0.03

1.3

1.2

—

(3007853) Bacteria identified in Skin by Aerobe culture

179

0.94

0.03

1.9

1.5

—

(3000963) Hemoglobin [Mass/volume] in Blood

179

1798

0.93

0.03

20.7

17.5

141.15

140.57

g/l

0.22

179

1774

(3026989) Triiodothyronine (T3) Free [Moles/volume] in Serum or Plasma

1.08

0.02

4.0

4.2

4.33

4.83

pmol/l

—

(3035941) MCH [Entitic mass]

179

1797

0.94

0.01

20.4

17.4

30.36

30.26

0.43

179

1773

(3024731) MCV [Entitic volume]

179

1797

0.94

0.01

20.5

17.4

90.14

90.22

0.09

179

1774

(3016771) Amylase [Enzymatic activity/volume] in Serum or Plasma

467

0.98

0.01

2.8

2.6

48.15

56.39

u/l

1.53

439

(3021589) Normoblasts [#/volume] in Blood

657

0.98

0.01

12.9

9.2

0.00

e9/l

0.91

531

(3002179) Metamyelocytes/100 leukocytes in Blood

114

0.96

0.00

3.5

4.5

0.80

0.46

—

(3020682) Albumin/Creatinine [Ratio] in Urine

351

1.00

0.00

4.2

4.1

3.43

9.42

mg/mmol

1.46

234

(40760892) CBC W Ordered Manual Differential panel - Blood

742

1.00

0.00

8.4

6.8

—

(3017181) Myelocytes/100 leukocytes in Blood

127

1.03

0.00

3.1

4.4

1.58

0.65

—

(3001604) Monocytes [#/volume] in Blood

773

0.99

0.00

7.3

6.4

0.53

0.58

e9/l

1.27

686

(3006315) Basophils [#/volume] in Blood

775

0.99

0.00

7.3

6.4

0.04

e9/l

0.16

689

(3021440) Promyelocytes/100 leukocytes in Blood

118

1.02

0.00

3.2

4.6

1.00

0.15

—

(21491868) Cryoglobulin [Mass/volume] in Serum

0.00

0.0

1.0

—

(3011547) Coagulation factor VII activity actual/normal in Platelet poor plasma by Coagulation assay

0.00

0.0

1.1

—

101.25

—

(3022058) Hepatitis B virus DNA [Presence] in Serum or Plasma by NAA with probe detection

0.00

0.0

1.4

—

(3019601) Blood group antibody investigation [Interpretation] in Plasma or RBC

0.00

0.0

1.3

—

(40758292) HTLV I+II Ab panel - Serum

0.00

0.0

1.4

—

(3007821) Glucose [Moles/volume] in Serum or Plasma --baseline

0.00

0.0

1.0

—

8.60

—

(42529200) Cancer Ag 15-3 [Units/volume] in Serum or Plasma by Immunoassay

0.00

0.0

5.1

—

27.59

—

(44816752) ERBB2 gene copy number/nucleus in Tissue by FISH

0.00

0.0

1.1

—

(3034603) RHD gene allele [Genotype] in Blood or Tissue by Molecular genetics method Nominal

0.00

0.0

1.5

—

(3034988) Calcium [Moles/volume] in Capillary blood

0.00

0.0

1.1

—

1.20

—

(44816808) CXCL13 Ag [Mass/volume] in Cerebral spinal fluid

0.00

0.0

1.1

—

(42868414) European tick borne encephalitis virus IgM Ab [Presence] in Serum by Immunoassay

0.00

0.0

1.3

—

(40757349) CD3+CD4+ (T4 helper) cells/CD3+CD8+ (T8 suppressor cells) cells [# Ratio] in Blood

0.00

0.0

1.4

—

(36306090) Helicobacter pylori [Presence] in Tissue by Organism specific culture

0.00

0.0

1.0

—

(40771527) Human papilloma virus E6+E7 mRNA [Presence] in Cervix by NAA with probe detection

0.00

0.0

1.6

—

(3037692) Legionella sp identified in Specimen by Organism specific culture

0.00

0.0

1.3

—

(3037677) Mycoplasma pneumoniae IgM Ab [Titer] in Cerebral spinal fluid

0.00

-0.00

0.0

1.2

—

(42868421) Varicella zoster virus IgM Ab [Presence] in Cerebral spinal fluid by Immunoassay

0.00

-0.00

0.0

1.4

—

(3035062) Alkaline phosphatase.liver 1 [Enzymatic activity/volume] in Serum or Plasma

0.00

-0.00

0.0

1.1

—

53.00

—

(3047189) Immunofixation for 24 hour Urine

0.00

-0.00

0.0

1.7

—

(3035999) Lactate [Moles/volume] in Cerebral spinal fluid

0.00

-0.00

0.0

1.6

—

1.61

—

(3017569) Oxygen content in Arterial blood

0.00

-0.00

0.0

14.4

—

(1617658) Protocol used for examination of sentinel lymph nodes

0.00

-0.00

0.0

1.2

—

(3017704) Immunofixation for Urine

0.00

-0.00

0.0

1.1

—

(3050129) First trimester maternal screen panel - Serum or Plasma

0.93

-0.00

2.0

1.4

—

(40761849) Varicella zoster virus IgG Ab [Units/volume] in Cerebral spinal fluid by Immunoassay

0.00

-0.00

0.0

1.4

—

(3014271) Vancomycin [Susceptibility]

0.00

-0.00

0.0

2.1

—

(3025577) Chromium [Mass/volume] in Blood

0.00

-0.00

0.0

2.2

—

2.78

—

(3008536) Aspergillus sp Ab [Presence] in Serum

0.00

-0.00

0.0

1.8

—

(3001850) Coagulation factor XI activity actual/normal in Platelet poor plasma by Coagulation assay

0.00

-0.00

0.0

1.0

—

(40760548) Muscle specific receptor tyrosine kinase Ab [Units/volume] in Serum by Immunoassay

0.00

-0.00

0.0

1.2

—

(3002619) Bacteria identified in Specimen by Culture

0.00

-0.00

0.0

1.0

—

(3008152) Bicarbonate [Moles/volume] in Arterial blood

0.97

-0.00

6.2

16.0

24.80

25.28

mmol/l

—

(3006109) Coagulation factor IX activity actual/normal in Platelet poor plasma by Coagulation assay

0.00

-0.00

0.0

1.0

—

112.00

—

(46237023) Hepatitis B virus core and surface Ab and surface Ag panel - Serum

0.89

-0.00

1.8

1.3

—

(3036185) Alkaline phosphatase.liver 2 [Enzymatic activity/volume] in Serum or Plasma

0.00

-0.00

0.0

1.1

—

18.83

—

(3028433) Virus identified in Specimen by Culture

0.00

-0.00

0.0

1.7

—

(3037826) lamoTRIgine [Moles/volume] in Serum or Plasma

0.00

-0.00

0.0

2.3

—

16.61

—

(3016436) Lactate dehydrogenase [Enzymatic activity/volume] in Serum or Plasma

0.00

-0.00

0.0

6.0

—

228.80

—

(3027456) Digoxin [Moles/volume] in Serum or Plasma

0.00

-0.00

0.0

1.7

—

0.63

—

(3013139) Helicobacter pylori Ag [Presence] in Stool

0.89

-0.00

1.0

1.2

—

(3026470) Cobalt [Mass/volume] in Blood

0.00

-0.00

0.0

2.2

—

6.20

—

(3030429) Borrelia sp DNA [Identifier] in Specimen by NAA with probe detection

0.00

-0.00

0.0

1.0

—

(42868417) European tick borne encephalitis virus IgG Ab [Presence] in Serum by Immunoassay

0.00

-0.00

0.0

1.4

—

(3008898) HLA-B27 [Presence]

1.00

-0.00

1.1

—

(3002348) Coagulation factor XII activity actual/normal in Platelet poor plasma by Coagulation assay

0.00

-0.00

0.0

1.0

—

(3002823) Mycoplasma pneumoniae IgG Ab [Units/volume] in Cerebral spinal fluid

0.00

-0.00

0.0

1.2

—

(3005791) Eosinophil cationic protein (ECP) [Mass/volume] in Serum

0.00

-0.00

0.0

1.4

—

11.40

—

(3039602) Calcium.ionized [Moles/volume] adjusted to pH 7.4 in Capillary blood

0.00

-0.00

0.0

1.0

—

1.22

—

(40765096) Chromosome analysis panel by Banding

0.00

-0.00

0.0

1.5

—

(3004451) EKG impression Narrative

0.00

-0.00

0.0

1.4

—

(3044212) Herpes simplex virus 1+2 IgM Ab [Presence] in Cerebral spinal fluid

0.00

-0.00

0.0

1.6

—

Mortality – FinRegistry

↥

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

↥

Index endpoint: ST19_EFFEC_AIR_PRESSURE_WATER_PRESSURE – Effects of air pressure and water pressure

GWS hits: -

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

≡ Risteys

R13

FinnGen R12 + FinRegistry

FinnGen R11 + FinRegistry

FinnGen R10 + FinRegistry

FinnGen R10

FinnGen R9

FinnGen R8

FinnGen R7

FinnGen R6

FinnGen R5

FinnGen R4

FinnGen R3

Effects of air pressure and water pressure

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

1. Apply sex-specific rule

2. Check conditions

3. Check pre-conditions, main-only, mode, registry filters

4. Check minimum number of events

5. Include endpoints

6. Filter based on genotype QC (FinnGen only)

All original rules

Similar endpoints

Case counts by codes

Upset plot

Case counts by code for Effects of air pressure and water pressure (ST19_EFFEC_AIR_PRESSURE_WATER_PRESSURE)

Summary Statistics

-FinRegistry-

-FinnGen-

Key figures

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

CodeWAS

Matched cohort

LabWAS

Mortality – FinRegistry

Relationships between endpoints