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This is a non-core endpoint: only basic statistics are computed.

Carcinoma in situ of lip, oral cavity and pharynx

DOID Endpoint Browser

CD2_INSITU_LIPORALPHARYNX

Endpoint definition

↥

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

519972

1. Apply sex-specific rule

None

519972

2. Check conditions

None

519972

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — D00.0
  • Hospital discharge: ICD-9 — 2300
  • Cause of death: ICD-10 — D00.0
  • Cause of death: ICD-9 — 2300

2 out of 7 registries used, show all original rules.

93

4. Check minimum number of events

None

93

5. Include endpoints

None

93

6. Filter based on genotype QC (FinnGen only)

91

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
D00
Name in latin
Carcinoma in situ labii (oris)

Case counts by codes

↥

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

All Female Male
Number of individuals 91 33 58
Unadjusted period prevalence (%) 0.02 0.01 0.03
Median age at first event (years) 67.26 69.00 66.26

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
93
Matched controls
930
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
EJA10
NOMESCO Finland
Biopsy of tongue or floor of mouth
239.9
33.1
32
*
D00.00
ICD-10 Finland
Cancer in situ on the lip red border
+∞
27.4
25
*
C02.11
ICD-10 Finland
Malignant neoplasm of border of tongue
251.3
20.4
20
*
D00.06
ICD-10 Finland
Cancer in situ in another part of the tongue
+∞
19.4
18
*
EJB10
NOMESCO Finland
Excision of tumor or other lesion of apex or body of tongue
50.2
17.1
20
5
SAA03
NOMESCO Finland
Extended examination of mouth
5.9
16.6
56
189
K08.1
ICD-10 Finland
Loss of teeth due to accident, extraction or local periodontal disease
7.2
16.1
30
58
SBB00
NOMESCO Finland
Clinical photography of mouth and teeth
27.8
15.0
20
9
ECA20
NOMESCO Finland
Biopsy of gingiva
162.8
13.8
14
*
K13.79
ICD-10 Finland
Change in the oral mucosa UNS
27.4
13.5
18
8
TEA00
NOMESCO Finland
Biopsy of lip
81.3
13.0
14
*
D00.09
ICD-10 Finland
Unspecified cancer in situ in oral cavity and throat
+∞
12.8
12
*
EJB30
NOMESCO Finland
Excision of tumor or other lesion of floor of the mouth
149.3
12.8
13
*
K13.28
ICD-10 Finland
Other leukoplakia or disorder of epithelium of the palate or tongue
+∞
11.7
11
*
EAA30
NOMESCO Finland
Partial excision of lower lip
+∞
11.7
11
*
EKA10
NOMESCO Finland
iopsy of buccal mucosa
17.0
11.0
17
12
EAA10
NOMESCO Finland
Excision of lesion of lip
68.0
10.9
12
*
EN1BD
NOMESCO Finland
Very extensive CT examination of mouth and soft tissues of neck
37.3
10.6
13
*
D00.04
ICD-10 Finland
In situ cancer of the floor of the mouth
+∞
10.6
10
*
WZC00
NOMESCO Finland
Treatment plan or consultation
4.1
10.5
52
218
SBA00
NOMESCO Finland
Microbiological examinations
19.5
10.3
15
9
K13.78
ICD-10 Finland
Other change in the oral mucosa
20.3
9.7
14
8
D00.01
ICD-10 Finland
In situ cancer of the mucous membrane of the cheek
+∞
9.5
9
*
EP1AE
NOMESCO Finland
Neck ultrasound examination
8.4
9.5
21
31
JDB10
NOMESCO Finland
Percutaneous gastrostomy
41.1
9.2
11
*
A07AA02
ATC
nystatin; oral
7.9
9.2
21
33
PJD71
NOMESCO Finland
Extended sparing excision of cervical lymph nodes
55.4
8.9
10
*
504
Kela drug reimbursment
Conditions requiring daily forced enteral nutrition
22.6
8.7
12
6
EKB00
NOMESCO Finland
Excision of tumour or other lesion of cheek
98.6
8.6
9
*
EJ2S1
NOMESCO Finland
Photography of oral mucosa
86.7
7.5
8
*
8070/3-C00.1
ICD-O-3
Squamous cell carcinoma, NOS, of external lower lip
+∞
7.4
7
*
D00.05
ICD-10 Finland
In situ cancer of the pharyngeal part of the tongue
+∞
7.4
7
*
C00.1
ICD-10 Finland
Malignant neoplasm: External lower lip
+∞
7.4
7
*
B37.03
ICD-10 Finland
Chronic atrophic candida infection in the mouth
+∞
7.4
7
*
C03.0
ICD-10 Finland
Malignant neoplasm: Upper gum
+∞
7.4
7
*
K13.29
ICD-10 Finland
Indefinite leukoplakia
22.1
7.3
10
5
EP1CG
NOMESCO Finland
Extensive MRI examination of soft tissue of neck with high intesity magnet
22.1
7.3
10
5
SBB10
NOMESCO Finland
Dental impressions
8.3
7.0
15
21
GBB00
NOMESCO Finland
Tracheostomy
24.6
6.8
9
*
SXA10
NOMESCO Finland
Oral mucosal sampling
24.6
6.8
9
*
EP1DG
NOMESCO Finland
Very extensive examination of soft tissue of neck with high intesity magnet
74.8
6.5
7
*
C03.1
ICD-10 Finland
Malignant neoplasm: Lower gum
74.8
6.5
7
*
EDB00
NOMESCO Finland
Partial excision of mandible
74.8
6.5
7
*
EHA10
NOMESCO Finland
Biopsy of palate
74.8
6.5
7
*
EBB10
NOMESCO Finland
Insertion of dental implant
74.8
6.5
7
*
8070/3-C02.1
ICD-O-3
Squamous cell carcinoma, NOS, of border of tongue
+∞
6.3
6
*
D00.08
ICD-10 Finland
Other specified cancers in situ in oral cavity and throat
+∞
6.3
6
*
C06.0
ICD-10 Finland
Malignant neoplasm: Cheek mucosa
+∞
6.3
6
*
WX110
NOMESCO Finland
Infiltration anesthesia
3.4
6.2
71
453
130
Kela drug reimbursment
Malignant tumour
3.9
6.2
21
65
WZC05
NOMESCO Finland
Specialty-specific consultation based on referral by dentist or doctor
7.3
6.1
14
22

LabWAS

↥
OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
26
65
5.16
10.33
2.8
2.4
0.20
0.21
g/l
0.23
26
56
25
83
3.75
6.69
1.7
1.3
—
—
—
0
0
28
104
3.42
6.31
5.3
7.3
103.32
103.66
mmol/l
0.10
28
104
50
263
2.95
6.17
3.8
2.2
—
—
—
0
0
20
68
3.47
5.09
1.5
1.3
—
—
—
0
0
24
94
3.09
4.86
1.9
1.4
—
—
—
0
0
18
62
3.36
4.46
5.9
9.5
—
—
—
0
0
54
339
2.41
4.15
8.4
6.0
0.62
0.62
e9/l
0.04
44
294
19
71
3.11
4.13
1.3
1.4
368.00
353.85
titre
—
5
13
54
340
2.40
4.11
8.4
6.0
0.04
0.04
e9/l
0.00
45
295
26
119
2.64
3.91
2.6
1.7
—
—
—
0
0
54
348
2.32
3.80
8.4
6.1
1.77
1.77
e9/l
0.00
47
306
25
114
2.63
3.78
1.6
1.7
28.19
29.40
s
0.82
25
108
54
352
2.27
3.65
8.5
6.3
0.16
0.19
e9/l
1.15
47
304
38
218
2.26
3.45
3.6
2.5
—
—
—
0
0
22
99
2.60
3.39
6.6
7.9
0.57
1.60
mmol/l
0.67
17
76
11
265
0.34
3.06
3.1
3.1
—
—
—
0
0
39
238
2.10
2.95
7.4
4.4
—
—
—
0
0
48
317
2.06
2.94
6.1
5.9
58.06
59.11
%
0.21
43
295
6
9
7.03
2.91
1.5
1.0
—
—
—
0
0
18
79
2.59
2.90
3.2
2.8
19.00
8.72
umol/l
0.38
18
66
46
301
2.05
2.87
2.3
2.0
88.92
93.33
pmol/l
0.28
26
148
48
322
2.01
2.77
6.3
6.2
26.16
26.15
%
0.00
43
300
47
315
1.99
2.70
6.4
6.4
8.83
8.60
%
0.21
42
293
11
36
3.33
2.67
3.6
2.7
0.74
0.67
%
0.35
11
36
11
37
3.23
2.59
3.6
2.8
1.89
1.17
%
0.58
11
37
5
7
7.46
2.58
13.8
1.4
5.16
3.41
nmol/l
—
5
7
55
397
1.94
2.48
12.9
16.3
1.28
1.31
inr
—
10
117
35
217
1.98
2.46
3.4
3.1
0.39
0.48
e6/l
0.17
28
165
34
210
1.98
2.41
3.4
3.1
—
—
—
0
0
37
240
1.90
2.25
3.5
3.2
62.51
282.95
e6/l
0.40
30
191
29
173
1.98
2.25
10.9
6.4
—
—
—
0
0
28
165
2.00
2.25
1.3
1.5
—
—
—
0
0
47
330
1.86
2.23
8.2
6.7
—
—
—
0
0
12
49
2.66
2.20
5.3
3.1
129.33
129.04
g/l
0.02
12
49
55
408
1.85
2.17
15.2
10.1
4.20
4.39
e9/l
0.20
50
353
40
271
1.84
2.10
3.5
3.8
64.35
82.69
e6/l
0.13
29
203
6
15
4.20
2.07
2.8
2.0
—
—
—
0
0
6
16
3.93
1.97
12.0
3.9
—
—
—
0
0
13
61
2.31
1.81
1.2
1.4
—
—
—
0
0
81
704
2.17
1.73
31.4
16.2
38.18
24.47
mg/l
1.76
68
571
10
40
2.68
1.73
6.2
3.0
25.78
24.66
mmol/l
—
10
40
7
25
2.94
1.68
10.6
3.2
22.49
35.38
mg/l
—
7
20
10
43
2.48
1.65
9.5
7.5
—
—
—
0
0
15
79
2.07
1.60
1.2
1.6
—
—
—
0
0
9
37
2.58
1.53
1.3
1.8
—
—
—
0
0
43
320
1.64
1.51
9.5
11.4
0.00
0.00
e9/l
0.79
35
273
23
146
1.76
1.44
1.4
1.7
1263.69
1322.70
nmol/l
0.11
18
111
9
41
2.32
1.41
2.2
2.1
—
—
—
0
0
30
211
1.62
1.29
4.2
3.3
32.74
360.74
mg/l
0.58
24
139
8
37
2.27
1.25
3.4
4.5
—
—
—
0
0
19
119
1.75
1.24
2.7
2.7
1.51
2.19
e6/l
0.30
12
71
11
57
2.05
1.23
1.5
1.3
—
—
—
0
0
18
113
1.74
1.16
2.6
2.3
15.83
22.21
%
1.50
13
99
7
33
2.21
1.08
2.9
2.4
—
—
—
0
0
16
100
1.72
1.05
1.4
1.7
—
—
—
0
0
5
22
2.34
1.04
9.4
3.3
1.36
1.37
mmol/l
—
5
22
31
230
1.52
1.04
3.8
3.2
—
—
—
0
0
9
48
1.97
1.04
2.3
1.8
1.16
1.22
g/l
—
9
40
7
36
2.02
0.99
6.7
3.1
—
—
—
0
0
14
212
0.60
0.95
3.0
3.9
—
—
—
0
0
10
56
1.88
0.92
5.9
2.6
10.58
9.27
g/l
—
10
46
30
228
1.47
0.89
4.5
3.8
3.67
11.05
mg/mmol
1.40
24
145
6
30
2.07
0.88
1.5
1.2
86.00
142.49
u/ml
—
6
25
10
57
1.85
0.87
1.2
1.5
—
—
—
0
0
14
89
1.67
0.87
1.2
1.5
—
—
—
0
0
11
66
1.76
0.83
2.1
2.5
334.00
330.77
nmol/l
0.02
11
56
6
34
1.82
0.77
5.7
4.0
—
—
—
0
0
11
68
1.70
0.75
4.2
3.7
—
—
—
0
0
55
479
1.36
0.71
5.4
4.8
—
—
—
0
0
5
27
1.90
0.69
2.4
1.7
—
—
—
0
0
8
50
1.66
0.63
8.0
6.7
23.63
25.36
mmol/l
—
8
50
8
52
1.59
0.61
6.6
2.9
—
7.45
—
0
7
38
319
1.32
0.60
4.6
4.8
19.75
47.58
ng/l
1.95
30
256
0
23
0.00
0.59
0.0
1.0
—
—
—
0
0
10
65
1.60
0.58
6.5
3.7
—
—
—
0
0
22
172
1.37
0.55
4.9
4.1
—
—
—
0
0
9
63
1.47
0.54
11.9
4.4
—
—
—
0
0
15
111
1.42
0.50
1.5
1.4
1.20
14.50
u/ml
—
5
45
78
736
1.37
0.46
25.9
15.2
—
—
—
0
0
8
57
1.44
0.43
11.4
2.0
—
—
—
0
0
55
500
1.24
0.42
5.0
4.3
—
—
—
0
0
0
15
0.00
0.41
0.0
3.1
—
—
—
0
0
19
233
0.77
0.41
6.9
4.5
—
—
—
0
0
11
81
1.41
0.38
1.4
1.4
—
—
—
0
0
13
100
1.35
0.36
1.0
1.2
—
—
—
0
0
33
370
0.83
0.31
5.8
5.6
0.00
0.00
estimate
—
5
81
33
368
0.84
0.29
4.6
4.3
0.00
0.00
estimate
—
5
86
24
211
1.19
0.24
1.9
2.9
0.50
0.77
ug/l
1.27
14
141
78
753
1.22
0.23
37.6
19.1
83.83
82.96
umol/l
0.10
78
753
0
11
0.00
0.21
0.0
1.1
—
—
—
0
0
10
80
1.28
0.21
3.1
1.9
—
—
—
0
0
0
12
0.00
0.21
0.0
3.2
—
18.46
—
0
12
63
604
1.13
0.17
35.3
19.5
15.67
15.12
%
0.27
63
591
80
779
1.19
0.17
44.5
23.6
38.47
40.42
%
1.80
71
736
13
113
1.17
0.14
1.4
1.3
38.08
39.14
iu/ml
—
6
37
10
86
1.18
0.11
3.3
4.5
5.56
130.54
ug/l
—
10
75
5
43
1.17
0.10
2.0
3.0
0.27
0.06
e6/l
—
5
43
6
54
1.12
0.09
1.0
1.6
—
—
—
0
0
6
71
0.83
0.08
1.7
4.6
1.22
1.22
mmol/l
—
6
64
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
6.8
—
38.40
—
0
5
0
5
0.00
0.00
0.0
11.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.9
—
16.30
—
0
7
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
179.26
—
0
7
0
9
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
9
0.00
-0.00
0.0
2.4
—
—
—
0
0
0
6
0.00
-0.00
0.0
2.8
—
—
—
0
0
0
7
0.00
-0.00
0.0
2.0
—
36.36
—
0
7
0
9
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
262.57
—
0
7

Mortality – FinRegistry

↥

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

↥

Index endpoint: CD2_INSITU_LIPORALPHARYNX – Carcinoma in situ of lip, oral cavity and pharynx

GWS hits: -

This endpoint is excluded from FinRegistry analyses (omitted endpoint).