This is a non-core endpoint: only basic statistics are computed.
See its core counterpart CD2_INSITU_ORAL_EXALLC for full statistics.
Carcinoma in situ of oral cavity, oesophagus and stomach
CD2_INSITU_ORAL
No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleNone |
520210 |
2. Check conditionsNone |
520210 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
131 |
4. Check minimum number of eventsNone |
131 |
5. Include endpoints |
187 |
6. Filter based on genotype QC (FinnGen only) |
187 |
Control definitions (FinnGen only)
Controls for this endpoint are individuals that are not cases.
Extra metadata
- Level in the ICD hierarchy
- 2
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- D00-D09
- Name in latin
- Carcinoma in situ cavitatis oris, oesophagi sive ventriculi
Similar endpoints
↥List of similar endpoints to
Carcinoma in situ of oral cavity, oesophagus and stomach
based on the number of shared cases.
Similar with more cases:
- Carcinoma in situ of oral cavity, oesophagus and stomach
- In situ neoplasms
- In situ neoplasms
- Any event in hilmo or specialist outpatient
- Any prescribed medicine buy
Similar with less cases:
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
This endpoint is excluded from FinRegistry analyses (omitted endpoint).
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 187 | 57 | 130 |
| Unadjusted period prevalence (%) | 0.05 | 0.02 | 0.06 |
| Median age at first event (years) | 69.05 | 70.30 | 68.50 |
-FinnGen-
Age distribution of first events
-FinnGen-
Year distribution of first events
-FinnGen-
Cumulative Incidence Function
Not a core endpoint, no data to show.
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 169
- Matched controls
- 1690
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
D00.2
ICD-10 Finland
Carcinoma in situ: Stomach
+∞
23.5
22
*
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
5.5
23.3
95
320
D00.1
ICD-10 Finland
Carcinoma in situ: Oesophagus
+∞
22.4
21
*
C15.5
ICD-10 Finland
Malignant neoplasm: Lower third of oesophagus
112.7
19.0
20
*
D00.00
ICD-10 Finland
Cancer in situ on the lip red border
+∞
18.0
17
*
EJA10
NOMESCO Finland
Biopsy of tongue or floor of mouth
20.2
17.6
26
15
130
Kela drug reimbursment
Malignant tumour
6.0
15.2
45
96
C15.9
ICD-10 Finland
Malignant neoplasm: Oesophagus, unspecified
+∞
14.8
14
*
JCA45
NOMESCO Finland
Endoscopic mucosal or submucosal resection in oesophagus
163.5
14.7
15
*
K22.7
ICD-10 Finland
Barrett oesophagus
21.6
14.7
21
11
JDW98
NOMESCO Finland
Other transluminal endoscopic operation on stomach or duodenum
21.6
14.7
21
11
D00.06
ICD-10 Finland
Cancer in situ in another part of the tongue
+∞
13.7
13
*
C02.11
ICD-10 Finland
Malignant neoplasm of border of tongue
151.6
13.7
14
*
504
Kela drug reimbursment
Conditions requiring daily forced enteral nutrition
43.9
13.4
16
*
SBB00
NOMESCO Finland
Fotograf of mouth and teeth
18.7
13.4
20
12
D00.09
ICD-10 Finland
Unspecified cancer in situ in oral cavity and throat
+∞
12.7
12
*
JCF12
NOMESCO Finland
Endoscopic insertion of prosthetic tube into oesphagus
139.9
12.6
13
*
EKA10
NOMESCO Finland
Biopsy of cheek
23.4
12.3
17
8
8140/3-C16.0
ICD-O-3
Adenocarcinoma, NOS, of cardia, NOS
+∞
11.6
11
*
JCA52
NOMESCO Finland
Other endoscopic procedure using diathermy or heat in oesophagus
128.3
11.6
12
*
D13.0
ICD-10 Finland
Benign neoplasm: Oesophagus
128.3
11.6
12
*
WX002
NOMESCO Finland
Sedation and analgesia
3.8
11.0
53
182
WX402
NOMESCO Finland
General anaesthesia
4.5
10.8
41
113
C15.3
ICD-10 Finland
Malignant neoplasm: Upper third of oesophagus
+∞
10.5
10
*
JDB10
NOMESCO Finland
Percutaneous gastrostomy
34.9
10.5
13
*
EJB10
NOMESCO Finland
Excision of lesion of apex or body of tongue
34.9
10.5
13
*
K13.28
ICD-10 Finland
Other leukoplakia or disorder of epithelium of the palate or tongue
105.6
9.5
10
*
EJB30
NOMESCO Finland
Excision of lesion of floor of mouth
105.6
9.5
10
*
D00.04
ICD-10 Finland
In situ cancer of the floor of the mouth
+∞
9.5
9
*
C159, 8148, 2
ICD-O-3
NA
+∞
9.5
9
*
UJD02
NOMESCO Finland
Gastroscopy
5.5
9.2
27
56
A03FA01
ATC
metoclopramide; systemic, rectal
3.4
9.1
50
187
EN1BD
NOMESCO Finland
Very extensive CT examination of mouth and soft tissues of neck
29.2
8.6
11
*
ECA20
NOMESCO Finland
Biopsy of gingiva
29.2
8.6
11
*
D37.7
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Other digestive organs
9.3
8.5
17
20
EP1CG
NOMESCO Finland
Extensive MRI examination of soft tissue of neck with high intesity magnet
35.2
8.2
10
*
C16.9
ICD-10 Finland
Malignant neoplasm: Stomach, unspecified
35.2
8.2
10
*
TEA00
NOMESCO Finland
Biopsy of lip
23.4
8.1
11
5
WZC00
NOMESCO Finland
Planning of intervention or health care consultation
2.8
8.1
67
325
JCA55
NOMESCO Finland
Endoscopic dilatation of oesophagus
16.0
7.8
12
8
UJC12
NOMESCO Finland
Flexible oesophagoscopy
19.5
7.7
11
6
N02AA05
ATC
oxycodone; systemic
3.1
7.6
46
182
107
Kela drug reimbursment
Pernicious anaemia
8.3
7.6
16
21
C15.4
ICD-10 Finland
Malignant neoplasm: Middle third of oesophagus
83.6
7.5
8
*
C16.09
ICD-10 Finland
Malignant tumor of cardiac or other unspecified carcinoma
83.6
7.5
8
*
D00.01
ICD-10 Finland
In situ cancer of the mucous membrane of the cheek
+∞
7.3
7
*
C03.0
ICD-10 Finland
Malignant neoplasm: Upper gum
+∞
7.3
7
*
D37.1
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Stomach
21.1
7.2
10
5
EAA10
NOMESCO Finland
Excision of lesion of lip
21.1
7.2
10
5
K13.78
ICD-10 Finland
Other change in the oral mucosa
10.7
7.2
13
13
EP1AE
NOMESCO Finland
Neck ultrasound examination
6.0
7.2
19
35
SBA00
NOMESCO Finland
Microbiological examinations
9.9
6.9
13
14
K08.1
ICD-10 Finland
Loss of teeth due to accident, extraction or local periodontal disease
3.8
6.9
29
87
EP1DG
NOMESCO Finland
Very extensive examination of soft tissue of neck with high intesity magnet
41.8
6.8
8
*
XJD02
NOMESCO Finland
Peroral endoscopic ultrasonography
23.6
6.7
9
*
WX105
NOMESCO Finland
Surface analgesia on skin or mucosa
4.5
6.7
23
57
N02AB03
ATC
fentanyl; nasal, sublingual, transdermal
5.0
6.5
20
44
JCC12
NOMESCO Finland
Thoracoscopic or laparoscopic partial oesophagectomy
72.4
6.5
7
*
8140/3-C16.9
ICD-O-3
Adenocarcinoma, NOS, of stomach, NOS
72.4
6.5
7
*
R4190
NOMESCO Finland
Nutritional therapy
8.7
6.5
13
16
B03BA03
ATC
hydroxocobalamin; parenteral
4.1
6.3
24
66
JN4BD
NOMESCO Finland
Extensive body CT
3.4
6.3
30
100
GDA98
NOMESCO Finland
Other bronchoscopic incision, excision of lesion or repair of lung
27.8
6.3
8
*
C160, 8148, 2
ICD-O-3
NA
+∞
6.3
6
*
C03.1
ICD-10 Finland
Malignant neoplasm: Lower gum
+∞
6.3
6
*
EDB00
NOMESCO Finland
Partial excision of mandible
+∞
6.3
6
*
D00.05
ICD-10 Finland
In situ cancer of the pharyngeal part of the tongue
+∞
6.3
6
*
EAA30
NOMESCO Finland
Partial excision of lower lip
+∞
6.3
6
*
C06.0
ICD-10 Finland
Malignant neoplasm: Cheek mucosa
+∞
6.3
6
*
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
48
139
4.30
15.39
2.8
2.4
0.2
0.2
g/l
0.48
48
123
77
326
3.32
13.88
3.6
2.4
—
—
—
0
0
110
619
2.89
11.38
5.9
4.2
—
—
—
0
0
46
188
2.92
8.31
6.8
5.7
0.3
1.3
mmol/l
1.15
35
152
73
383
2.49
8.00
1.6
1.6
17.2
21.4
nmol/l
2.43
64
317
10
13
8.07
7.19
3.0
2.5
—
—
—
0
0
10
14
7.49
6.76
3.4
1.2
—
—
—
0
0
98
626
2.19
6.44
2.4
2.0
96.9
91.7
pmol/l
0.38
59
318
28
108
2.87
5.53
1.8
1.3
—
—
—
0
0
102
691
2.05
5.45
6.9
5.5
1.2
1.2
mmol/l
1.24
93
615
108
749
2.05
5.38
8.1
6.3
1.2
1.2
mmol/l
1.12
96
616
67
392
2.11
5.30
3.3
2.1
3.0
3.2
mg/l
0.44
59
334
31
138
2.49
4.63
6.9
5.4
1.7
1.5
mmol/l
0.21
31
129
32
147
2.42
4.47
2.3
2.8
3.2
5.5
ug/l
1.88
25
131
39
207
2.12
3.86
4.1
3.9
222.9
244.6
u/l
0.81
39
193
43
237
2.06
3.86
2.7
2.3
2.3
2.3
g/l
0.35
38
212
79
537
1.82
3.78
3.5
2.7
123.3
155.5
ug/l
0.89
73
487
19
73
2.78
3.77
1.8
2.2
3.1
0.8
ug/l
1.02
13
66
106
788
1.80
3.75
12.7
9.5
4.7
4.3
e9/l
0.55
96
677
21
86
2.62
3.70
8.6
7.1
23.8
24.8
mmol/l
0.94
21
79
77
529
1.77
3.50
4.1
3.3
1847.8
1790.7
ng/l
0.05
66
440
74
505
1.77
3.43
4.0
3.2
2.3
2.3
mmol/l
0.02
64
443
34
180
2.09
3.38
10.4
9.0
—
—
—
0
0
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
14
48
3.07
3.38
1.7
1.8
0.2
0.3
u/ml
—
6
25
45
264
1.93
3.37
2.4
2.0
—
—
—
0
0
40
228
1.96
3.25
2.8
2.4
17.7
22.5
%
1.54
30
199
25
120
2.25
3.16
1.9
1.5
—
—
—
0
0
33
178
2.04
3.12
2.1
1.8
—
—
—
0
0
46
283
1.83
2.96
5.1
3.4
155.7
118.2
ng/l
0.16
40
237
15
58
2.72
2.95
6.0
3.4
—
—
—
0
0
42
257
1.82
2.74
2.7
2.9
0.5
1.1
e6/l
1.99
28
158
32
181
1.93
2.65
2.0
1.9
—
—
—
0
0
124
1017
1.65
2.64
5.3
4.1
17.4
13.7
mm/h
1.32
119
918
75
555
1.59
2.38
2.6
2.3
79.4
76.2
nmol/l
0.46
64
475
10
36
2.88
2.24
2.0
1.3
—
—
—
0
0
19
95
2.11
2.19
2.3
1.7
—
—
—
0
0
82
631
1.53
2.14
5.1
4.5
39.5
52.0
ng/l
0.45
66
490
74
558
1.54
2.12
3.6
3.5
—
—
—
0
0
7
20
3.59
2.07
1.7
1.8
—
—
—
0
0
9
32
2.90
2.03
2.3
1.4
—
—
—
0
0
7
21
3.42
1.98
1.7
1.7
—
—
—
0
0
7
21
3.42
1.98
8.6
2.4
4.0
3.4
nmol/l
—
7
21
7
21
3.42
1.98
1.7
1.7
—
—
—
0
0
7
21
3.42
1.98
1.7
1.7
—
—
—
0
0
7
21
3.42
1.98
1.7
1.7
—
—
—
0
0
45
307
1.61
1.96
1.6
1.7
1.4
1.5
mg/l
0.13
37
236
113
943
1.50
1.95
3.3
3.7
14.8
15.0
pmol/l
0.31
103
821
7
22
3.26
1.90
1.7
1.7
—
—
—
0
0
47
327
1.58
1.89
1.7
1.8
1164.8
1255.6
nmol/l
0.27
34
244
8
28
2.94
1.88
1.4
1.5
—
—
—
0
0
5
12
4.25
1.83
1.2
1.3
—
—
—
0
0
38
255
1.62
1.77
1.7
1.9
29.4
29.7
s
0.14
38
245
7
24
2.99
1.74
1.4
1.3
—
—
—
0
0
20
115
1.83
1.60
3.8
3.6
69.1
59.9
ml/min/173m2
—
8
49
9
37
2.50
1.50
1.7
1.6
—
—
—
0
0
9
38
2.44
1.48
1.3
2.6
—
—
—
0
0
7
28
2.56
1.46
1.0
1.2
—
—
—
0
0
7
28
2.56
1.46
1.6
1.1
—
—
—
0
0
35
244
1.53
1.39
3.0
3.2
1.1
1.8
e6/l
0.58
21
146
9
41
2.25
1.39
1.8
1.7
—
—
—
0
0
9
41
2.25
1.39
1.8
1.7
—
—
—
0
0
148
1347
1.47
1.34
32.8
17.0
33.6
25.6
mg/l
1.72
135
1114
28
188
1.58
1.31
4.6
4.7
30.6
31.3
%
0.11
16
121
9
171
0.50
1.25
3.0
3.9
—
—
—
0
0
56
438
1.40
1.24
3.7
3.3
0.3
0.4
e6/l
0.55
44
329
82
684
1.35
1.22
2.9
2.6
—
—
—
0
0
6
26
2.35
1.19
1.2
1.5
—
—
—
0
0
6
26
2.35
1.19
1.0
2.0
—
—
—
0
0
10
50
2.06
1.19
1.5
1.3
—
—
—
0
0
13
72
1.87
1.18
1.0
2.2
—
—
—
0
0
13
72
1.87
1.18
1.0
2.2
4.2
3.8
g/l
—
7
51
13
72
1.87
1.18
1.0
2.2
8.0
7.5
g/l
—
7
54
12
65
1.90
1.16
3.2
2.2
—
—
—
0
0
7
30
2.38
1.13
1.4
1.6
—
—
—
0
0
7
30
2.38
1.13
1.4
1.6
—
—
—
0
0
132
1193
1.36
1.11
4.7
4.5
2.1
2.0
mu/l
0.31
120
1045
8
41
1.99
1.10
1.3
1.1
—
—
—
0
0
7
32
2.23
1.09
1.3
1.7
—
—
—
0
0
9
48
1.92
1.02
1.3
1.5
—
—
—
0
0
6
27
2.26
0.94
1.3
1.7
—
—
—
0
0
6
27
2.26
0.94
1.0
2.0
—
22.9
—
0
7
8
42
1.94
0.90
1.3
1.1
—
—
—
0
0
10
56
1.83
0.89
1.3
1.3
—
—
—
0
0
10
57
1.80
0.85
1.2
1.8
—
—
—
0
0
126
1153
1.28
0.84
34.3
17.1
35.6
39.9
%
2.92
79
745
6
32
1.90
0.82
2.0
1.7
—
—
—
0
0
10
59
1.73
0.77
3.2
4.1
—
3.7
—
0
6
10
59
1.73
0.77
3.3
4.2
23.4
31.9
mg/l
—
10
46
10
60
1.70
0.73
2.9
1.9
—
—
—
0
0
5
26
1.95
0.71
1.2
1.7
—
—
—
0
0
48
400
1.27
0.68
2.9
2.9
19155.8
6212.4
umol/l
0.47
42
337
31
383
0.77
0.62
4.4
4.5
0.0
0.0
estimate
—
6
134
8
52
1.56
0.60
1.1
1.7
—
—
—
0
0
6
97
0.61
0.53
1.8
1.3
—
—
—
0
0
22
171
1.32
0.53
1.3
1.3
2.0
12.2
u/ml
—
5
64
132
1255
1.18
0.42
7.6
6.4
42.4
41.4
mmol/mol
0.59
120
1150
103
1095
0.87
0.40
39.8
20.5
14.3
14.0
%
1.54
103
1071
5
35
1.44
0.39
1.0
1.4
—
—
—
0
0
5
36
1.40
0.38
1.4
1.2
—
—
—
0
0
6
45
1.34
0.34
1.7
1.4
—
—
—
0
0
48
528
0.88
0.29
4.3
4.5
—
—
—
0
0
146
1414
1.15
0.29
37.8
19.9
85.4
84.9
umol/l
0.07
146
1414
28
243
1.18
0.29
1.6
1.2
0.7
0.8
u/ml
—
8
66
131
1262
1.13
0.28
27.7
16.3
72.7
74.6
ml/min/173m2
0.46
118
1043
8
67
1.20
0.26
1.5
2.8
4.0
4.3
pmol/l
—
8
56
63
586
1.11
0.25
3.5
4.4
16.9
21.5
%
1.53
22
285
9
77
1.18
0.24
2.2
4.2
24.2
24.2
mmol/l
—
9
71
6
82
0.72
0.24
1.3
1.7
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
12
0.00
0.21
0.0
1.5
—
—
—
0
0
5
43
1.17
0.21
1.2
1.0
—
—
—
0
0
0
13
0.00
0.21
0.0
1.1
—
—
—
0
0
16
138
1.17
0.18
1.3
1.5
—
—
—
0
0
10
82
1.23
0.17
2.1
4.0
0.2
0.2
e6/l
—
10
82
22
196
1.14
0.17
1.3
1.2
30.9
38.3
iu/ml
—
8
67
37
346
1.09
0.13
1.5
1.8
566.2
427.1
pmol/l
0.43
27
280
76
732
1.06
0.13
5.5
5.0
1.7
2.7
ug/l
1.16
70
647
135
1324
1.07
0.12
5.3
5.3
2.3
2.6
mmol/l
2.67
126
1179
128
1303
0.94
0.10
5.6
5.0
6.3
6.1
mmol/l
0.78
119
1157
127
1252
1.04
0.07
4.3
4.2
1.4
1.3
mmol/l
0.75
116
1105
131
1293
1.04
0.06
4.8
4.7
4.2
4.4
mmol/l
1.40
121
1164
68
665
1.04
0.05
4.1
4.3
0.0
0.0
estimate
—
6
131
65
660
0.98
0.02
5.6
5.7
0.0
0.0
estimate
—
6
140
129
1284
1.02
0.00
4.8
4.6
1.4
1.4
mmol/l
0.21
119
1143
43
429
1.00
0.00
1.8
3.0
0.7
0.8
ug/l
0.36
25
285
66
661
1.00
0.00
4.0
4.3
0.0
0.0
estimate
—
6
143
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
1.6
—
—
—
0
0
(40770918) von Willebrand factor (vWf).activity actual/normal in Platelet poor plasma by Immunoassay
0
5
0.00
0.00
0.0
6.4
—
117.2
—
0
5
0
5
0.00
0.00
0.0
1.6
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
110.0
—
0
5
0
6
0.00
0.00
0.0
1.2
—
1.3
—
0
6
0
7
0.00
0.00
0.0
1.3
—
—
—
0
0
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
11.2
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.5
—
112.0
—
0
6
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
0.00
0.0
2.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
Mortality – FinRegistry
↥This endpoint is excluded from FinRegistry analyses (omitted endpoint).
Relationships between endpoints
↥Index endpoint: CD2_INSITU_ORAL – Carcinoma in situ of oral cavity, oesophagus and stomach
GWS hits: -
This endpoint is excluded from FinRegistry analyses (omitted endpoint).