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Congenital malformations of breast

DOID EFO Endpoint Browser PheWeb

Q17_CONGEN_MALFO_BREAST

Endpoint definition

↥

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — Q83
  • Cause of death: ICD-10 — Q83

2 out of 7 registries used, show all original rules.

646

4. Check minimum number of events

None

646

5. Include endpoints

None

646

6. Filter based on genotype QC (FinnGen only)

646

Control definitions (FinnGen only)

Control exclude
Q17_OTHER_CONGEN_MALFO

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF4
Parent code in ICD-10
Q8
Name in latin
Malformationes congenitae mammae

Case counts by codes

↥

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 4263 4107 135
Only index persons 4143 4029 114
Unadjusted period prevalence (%)
Whole population 0.11 0.12 0.00
Only index persons 0.14 0.15 0.00
Median age at first event (years)
Whole population 29.72 30.19 14.84
Only index persons 29.83 30.23 15.89

-FinnGen-

Key figures

All Female Male
Number of individuals 646 635 11
Unadjusted period prevalence (%) 0.21 0.22 0.00
Median age at first event (years) 32.68 32.48 44.00

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS (R11)

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
580
Matched controls
5799
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
Q83.8
ICD-10 Finland
Other congenital malformations of breast
+∞
323.0
293
*
Q83.1
ICD-10 Finland
Accessory breast
+∞
239.7
213
*
HAD10
NOMESCO Finland
Augmentation of breast using prosthesis
190.5
119.4
121
8
HAC30
NOMESCO Finland
Excision of supernumerary mammary gland or mamilla
897.1
81.5
78
*
HAD40
NOMESCO Finland
Mastopexy
185.7
64.4
66
*
Q83.9
ICD-10 Finland
Congenital malformation of breast, unspecified
+∞
63.7
60
*
ZZF00
NOMESCO Finland
Graft of adipose tissue
39.2
47.7
60
17
HAD99
NOMESCO Finland
Other plastic operation on breast
40.9
47.3
59
16
Q83.3
ICD-10 Finland
Accessory nipple
+∞
36.9
35
*
HA1AE
NOMESCO Finland
Ultrasound examination of mammary glands
5.8
35.8
109
221
HAD50
NOMESCO Finland
Removal of prosthetic implant from breast
45.0
28.0
34
8
HAE99
NOMESCO Finland
Other reconstruction of breast
20.4
26.9
40
21
HAD00
NOMESCO Finland
Augmentation mammoplasty
146.8
26.9
28
*
ZXA10
NOMESCO Finland
Bilateral
3.7
26.3
132
433
WX404
NOMESCO Finland
Intravenous generell anesthesy
3.0
24.0
172
725
HAD30
NOMESCO Finland
Reduction mammoplasty with transposition of areola
5.4
21.4
67
138
N64.2
ICD-10 Finland
Atrophy of breast
206.8
19.7
20
*
QBE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin of trunk
4.7
18.1
64
150
HA1AA
NOMESCO Finland
X-ray mammography
4.1
16.9
69
186
N64.8
ICD-10 Finland
Other specified disorders of breast
19.2
16.1
24
13
QBJ00
NOMESCO Finland
Liposuction in trunk
19.9
15.7
23
12
HAB00
NOMESCO Finland
Excision of lesion of mammary gland
6.1
15.1
41
71
T85.4
ICD-10 Finland
Mechanical complication of breast prosthesis and implant
23.0
14.3
20
9
WX408
NOMESCO Finland
General anesthesy, balanced
2.2
14.2
166
879
HAD60
NOMESCO Finland
Replacement of prosthetic implant in breast
43.6
14.2
17
*
N64.9
ICD-10 Finland
Disorder of breast, unspecified
9.4
13.9
28
31
N62
ICD-10 Finland
Hypertrophy of breast
3.8
13.3
57
161
Z42.1
ICD-10 Finland
Follow-up care involving plastic surgery of breast
14.5
12.8
21
15
6114A
ICD-9 Finland
Other disorders of breast, Atrophy of breast
44.2
11.0
13
*
QB2S1
NOMESCO Finland
Photography of skin or subcutaneous tissue in chest
13.2
10.7
18
14
Q83.0
ICD-10 Finland
Congenital absence of breast with absent nipple
+∞
10.4
10
*
N64.5
ICD-10 Finland
Other signs and symptoms in breast
4.9
9.8
31
66
N02BE01
ATC
paracetamol; systemic, rectal
2.0
9.6
483
4145
ZXA05
NOMESCO Finland
Left side
2.1
9.4
113
593
Q83
ICD-10 Finland
Congenital malformations of breast
+∞
9.4
9
*
9729
FHL
Other measure in this category
22.1
9.4
13
6
HAB99
NOMESCO Finland
Other partial excision of mammary gland
5.8
8.8
24
43
WX402
NOMESCO Finland
General anaesthesia
2.1
8.7
112
606
HAE00
NOMESCO Finland
Reconstruction of breast using prosthesis
13.0
8.4
14
11
LC2BE
NOMESCO Finland
Transvaginal ultrasound examination of uterus, parametria and lower abdomen
1.7
8.3
247
1765
Y83
ICD-10 Finland
Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
3.2
8.2
41
133
QBJ99
NOMESCO Finland
Other aesthetic correction of skin of trunk
+∞
7.3
7
*
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.6
7.0
235
1716
N60.9
ICD-10 Finland
Benign mammary dysplasia, unspecified
14.0
6.9
11
8
P01AB01
ATC
metronidazole; oral, rectal
1.6
6.8
242
1786
ZXA00
NOMESCO Finland
Right side
1.9
6.8
105
605
THW99
NOMESCO Finland
Other minor procedure in surgery of mammary gland
5.3
6.7
19
37
QBB10
NOMESCO Finland
Major dressing of wound of skin of trunk
3.4
6.4
29
88
QBE20
NOMESCO Finland
Excision and repair of scar or web of skin of trunk
8.3
6.4
13
16
N63
ICD-10 Finland
Unspecified lump in breast
2.3
6.2
53
240
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
1.6
6.1
182
1277
R10.1
ICD-10 Finland
Pain localized to upper abdomen
1.9
6.0
94
545

LabWAS

↥
OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
123
653
2.09
11.20
1.3
1.2
—
—
—
0
0
177
1091
1.86
10.38
2.8
3.0
100.7
98.4
%
0.75
172
1054
442
3614
1.71
8.89
6.4
5.9
70.0
71.8
u/l
0.59
413
3389
238
1661
1.69
8.84
3.6
4.0
37.3
37.1
g/l
0.27
219
1549
299
2223
1.64
8.63
2.1
1.9
—
—
—
0
0
228
1618
1.63
7.71
1.8
1.9
—
—
—
0
0
16
33
4.95
7.44
1.1
1.0
—
—
—
0
0
454
3826
1.63
7.25
3.9
3.6
8.7
9.1
mm/h
0.45
422
3577
193
1379
1.57
6.09
2.4
2.2
57.7
54.8
u/l
0.44
176
1277
569
5171
1.84
5.99
9.6
8.8
3.9
3.9
mmol/l
0.45
554
4994
309
2451
1.50
5.97
6.3
5.3
7.6
7.8
%
0.47
287
2310
307
2433
1.50
5.95
6.0
5.1
2.8
2.6
%
0.49
283
2266
320
2558
1.50
5.94
6.0
5.1
30.7
30.0
%
0.67
296
2405
593
5465
2.04
5.93
11.1
9.4
18.4
18.1
mg/l
0.09
459
4160
332
2675
1.50
5.92
4.2
3.9
—
—
—
0
0
296
2332
1.50
5.88
6.1
5.2
0.7
0.7
%
0.42
270
2176
291
2286
1.50
5.86
4.8
4.6
9.4
9.3
umol/l
0.04
271
2130
316
2528
1.49
5.79
5.8
4.9
55.6
56.4
%
0.65
293
2376
546
4916
1.71
5.78
14.0
11.4
13.3
13.4
%
1.63
537
4825
55
278
2.07
5.65
1.3
1.4
10.5
10.4
u/l
0.01
40
229
566
5157
1.79
5.61
9.5
8.7
139.4
139.5
mmol/l
0.52
554
4994
129
862
1.62
5.32
2.4
2.4
109.6
79.6
ug/g
0.72
100
661
212
1587
1.50
5.27
6.3
5.2
—
—
—
0
0
368
3076
1.46
5.15
2.7
2.7
—
—
—
0
0
316
2580
1.44
4.94
5.8
5.2
0.5
0.5
e9/l
0.06
274
2294
317
2593
1.44
4.89
5.8
5.2
0.0
0.0
e9/l
0.15
274
2298
96
609
1.68
4.84
1.4
1.4
20.7
24.6
iu/l
0.64
77
521
328
2705
1.43
4.81
6.2
5.4
0.2
0.2
e9/l
0.53
289
2429
246
1951
1.42
4.36
4.9
4.9
1.2
1.2
mmol/l
0.30
208
1624
324
2697
1.40
4.34
5.8
5.1
2.0
2.0
e9/l
0.02
289
2435
514
4657
1.51
4.24
4.4
4.3
14.2
14.3
pmol/l
0.04
480
4343
20
73
2.80
4.22
2.4
2.1
—
—
—
0
0
351
2973
1.40
4.19
8.1
7.5
3.7
3.9
e9/l
1.44
307
2625
36
180
2.06
3.86
1.3
1.2
—
—
—
0
0
638
6209
3.22
3.79
17.4
14.2
267.0
267.3
e9/l
0.05
627
6087
40
213
1.94
3.62
1.7
1.5
0.9
0.4
nmol/l
0.45
31
180
80
522
1.61
3.62
1.8
2.0
396.5
382.3
nmol/l
0.24
71
481
216
1719
1.39
3.62
4.1
4.3
1.2
1.2
mmol/l
0.40
195
1554
43
236
1.88
3.57
1.7
1.6
—
—
—
0
0
430
3819
1.38
3.56
4.5
3.8
—
—
—
0
0
638
6216
3.13
3.51
17.4
14.2
6.7
6.8
e9/l
0.24
626
6080
61
374
1.70
3.51
2.0
2.0
3.8
4.3
e9/l
1.08
51
323
638
6214
3.16
3.50
17.3
14.2
4.4
4.5
e12/l
0.78
626
6088
207
1646
1.38
3.46
1.7
1.7
98.7
97.2
pmol/l
0.19
106
890
56
352
1.65
2.96
2.8
2.2
—
—
—
0
0
115
847
1.44
2.96
2.5
2.3
546.7
539.7
mosm/kgh2o
0.07
99
726
150
1164
1.38
2.85
3.4
3.3
7.4
7.4
ph
0.24
27
223
18
77
2.38
2.84
2.7
2.3
—
—
—
0
0
87
612
1.49
2.83
1.2
1.1
—
—
—
0
0
610
5857
1.74
2.73
10.6
9.0
—
—
—
0
0
34
190
1.83
2.72
2.1
1.8
21.2
20.6
s
0.54
28
160
157
1238
1.35
2.69
6.4
5.8
—
—
—
0
0
22
106
2.11
2.66
1.0
1.1
—
—
—
0
0
121
918
1.39
2.63
2.3
2.3
8.7
10.6
e6/l
0.37
108
799
573
5432
1.49
2.62
12.6
10.1
39.3
39.7
%
0.95
493
4496
164
1311
1.34
2.56
2.9
2.6
522.5
79.9
e6/l
0.44
129
976
318
2779
1.28
2.56
4.4
4.2
0.0
0.0
estimate
0.42
68
593
84
600
1.46
2.54
1.9
1.7
—
—
—
0
0
73
508
1.49
2.52
2.2
2.2
23.9
24.1
%
0.04
64
421
274
2358
1.28
2.46
7.9
7.3
0.0
0.0
e9/l
1.35
215
1958
112
848
1.39
2.46
4.0
3.3
—
—
—
0
0
251
2137
1.29
2.45
2.6
2.8
—
—
—
0
0
319
2805
1.27
2.38
3.3
3.1
0.0
0.0
estimate
0.80
69
581
148
1187
1.32
2.24
2.9
2.5
0.2
0.3
e6/l
0.46
114
866
301
2644
1.26
2.22
3.5
3.6
5.9
6.2
mmol/l
2.29
277
2337
313
2764
1.26
2.20
3.2
3.1
0.0
0.0
estimate
0.00
70
575
150
1209
1.31
2.19
2.8
2.5
—
—
—
0
0
43
276
1.60
2.15
3.2
3.8
11.5
6.5
ug/l
0.36
29
204
555
5270
1.38
2.13
5.1
5.0
1.6
1.9
mu/l
0.69
527
4998
13
55
2.39
2.13
1.2
1.3
—
—
—
0
0
205
1727
1.27
2.13
3.3
3.0
84.6
55.0
e6/l
0.38
139
1083
11
43
2.59
2.10
1.1
1.0
—
—
—
0
0
163
1336
1.29
2.10
4.9
4.5
1.0
1.0
inr
0.67
55
492
22
118
1.89
2.04
2.0
2.6
—
—
—
0
0
18
90
2.03
2.02
2.2
2.3
7.4
7.4
ph
0.01
13
73
174
1445
1.28
2.02
2.8
2.8
2.4
2.3
mmol/l
0.48
160
1308
186
1560
1.27
1.99
2.1
2.2
—
—
—
0
0
19
99
1.95
1.92
1.1
1.1
—
—
—
0
0
357
3230
1.24
1.92
3.0
2.9
64.2
56.6
ug/l
0.88
336
3040
86
652
1.37
1.89
3.2
2.8
70.5
364.6
ng/l
1.17
40
323
405
3717
1.24
1.89
4.5
3.9
51.4
550.9
e6/l
—
5
38
72
535
1.39
1.80
3.7
3.2
—
—
—
0
0
8
29
2.78
1.79
1.1
1.1
—
—
—
0
0
50
350
1.46
1.73
1.2
1.2
—
—
—
0
0
145
1203
1.26
1.68
1.8
1.8
—
—
—
0
0
153
1279
1.26
1.66
2.2
2.0
2.4
2.7
mg/l
0.66
123
1093
71
535
1.37
1.64
1.8
1.8
28.8
29.2
s
0.45
71
519
6
20
3.02
1.58
2.0
2.5
0.3
0.2
e9/l
—
6
20
76
584
1.34
1.56
2.2
2.1
2.5
2.5
g/l
0.26
68
526
85
666
1.32
1.53
1.9
2.3
2.4
2.4
mmol/l
0.23
72
575
11
51
2.18
1.51
1.5
1.4
—
—
—
0
0
511
4858
1.25
1.50
3.5
3.3
5.6
5.5
mmol/l
0.07
470
4539
188
1625
1.22
1.50
1.4
1.3
1.1
2.0
u/ml
0.76
51
439
127
1053
1.26
1.48
1.3
1.3
2.4
10.8
u/ml
2.97
45
444
9
38
2.39
1.46
1.1
1.1
—
—
—
0
0
5
16
3.14
1.44
1.8
2.2
—
—
—
0
0
160
1370
1.22
1.39
1.5
1.4
2.1
2.0
g/l
0.37
96
855
7
29
2.43
1.39
3.3
2.0
—
—
—
0
0
128
1071
1.24
1.38
1.4
1.3
15.4
25.0
iu/ml
1.29
44
343
18
104
1.75
1.38
2.3
2.6
—
—
—
0
0
83
660
1.30
1.36
2.2
2.1
14.9
14.8
umol/l
0.03
76
596
250
2239
1.19
1.35
2.2
2.1
—
—
—
0
0
457
4318
1.20
1.31
4.2
4.0
36.5
37.2
mmol/mol
1.34
432
4090
16
91
1.78
1.30
1.1
1.3
—
—
—
0
0
127
1070
1.23
1.29
1.4
1.5
—
—
—
0
0
118
987
1.24
1.28
2.4
2.6
—
—
—
0
0
6
25
2.41
1.24
3.5
2.0
—
—
—
0
0
46
340
1.38
1.24
1.4
1.3
—
—
—
0
0
71
561
1.30
1.23
1.7
1.5
—
—
—
0
0
48
358
1.37
1.22
2.8
3.0
—
—
—
0
0
192
1694
1.19
1.21
3.0
2.7
—
—
—
0
0
139
1191
1.21
1.20
2.7
3.0
—
—
—
0
0
6
26
2.32
1.19
3.3
3.0
—
—
—
0
0
36
257
1.42
1.18
1.1
1.1
—
—
—
0
0
110
922
1.23
1.18
1.3
1.4
20.6
21.0
nmol/l
0.12
93
805
26
174
1.51
1.17
1.3
1.2
—
—
—
0
0
66
522
1.29
1.15
2.2
2.1
6.6
5.0
umol/l
0.33
48
418
140
1209
1.20
1.12
1.9
1.6
0.9
0.7
mg/l
0.47
109
888
13
73
1.80
1.11
2.6
2.4
5.1
5.0
kpa
0.13
13
73
7
31
2.27
1.10
2.1
3.3
—
—
—
0
0
30
210
1.45
1.10
1.2
1.1
0.7
1.7
u/ml
0.72
13
82
12
66
1.83
1.09
1.2
1.3
—
—
—
0
0
15
89
1.70
1.08
1.3
1.6
—
—
—
0
0
7
32
2.20
1.08
1.0
1.2
1195.7
1646.4
miu/ml
—
7
32
31
220
1.43
1.07
2.6
2.1
8.2
4.5
umol/l
0.55
25
161
34
246
1.40
1.06
2.3
1.7
—
—
—
0
0
27
187
1.46
1.05
1.9
2.1
—
—
—
0
0
50
386
1.32
1.05
1.3
1.2
—
—
—
0
0
26
179
1.47
1.04
1.1
1.1
1.5
0.9
u/ml
0.43
11
77
53
413
1.31
1.04
1.3
1.3
—
—
—
0
0
16
98
1.65
1.04
2.9
3.3
19.5
26.8
mg/l
—
8
64
9
46
1.97
1.04
1.0
1.1
—
—
—
0
0
59
467
1.29
1.04
2.9
3.6
4.5
4.6
pmol/l
0.54
53
418
5
22
2.28
1.03
1.0
1.1
6.4
6.7
nmol/l
—
5
22
37
275
1.37
0.99
1.1
1.2
—
—
—
0
0
73
597
1.25
0.99
1.5
1.4
—
—
—
0
0
80
666
1.23
0.94
1.1
1.2
92.6
160.6
iu/ml
1.43
28
284
6
27
2.23
0.93
1.8
3.4
—
—
—
0
0
136
1195
1.17
0.90
2.8
3.2
1.0
1.0
kg/l
0.06
21
170
234
2145
1.14
0.88
1.9
1.8
—
—
—
0
0
26
187
1.41
0.86
2.0
2.9
7.4
7.4
ph
—
5
25
167
1501
1.15
0.83
3.5
3.3
0.0
0.0
estimate
1.08
69
589
26
189
1.39
0.82
1.2
1.1
2.4
5.9
u/ml
1.09
13
100
12
73
1.66
0.82
2.7
2.4
9.2
9.4
kpa
0.21
12
73
73
612
1.22
0.82
1.8
1.6
1428.8
1170.6
nmol/l
0.56
64
468
28
207
1.37
0.80
3.1
2.1
64.1
72.0
e9/l
0.91
20
144
20
139
1.45
0.80
2.2
3.0
25.1
24.2
mmol/l
0.41
20
125
6
33
1.83
0.79
1.2
1.3
5.1
6.0
ug/l
—
6
27
15
98
1.54
0.79
5.1
3.0
1.4
1.2
mg/l
0.24
15
87
12
74
1.63
0.78
1.5
1.8
5965.3
13586.2
e6/l
—
7
57
12
74
1.63
0.78
1.0
1.1
—
—
—
0
0
17
115
1.49
0.77
4.2
3.6
3.9
4.3
e9/l
0.41
17
115
6
34
1.77
0.76
1.7
1.3
—
—
—
0
0
0
28
0.00
0.76
0.0
1.7
—
—
—
0
0
29
219
1.34
0.74
5.2
6.5
—
—
—
0
0
7
38
1.85
0.73
2.9
2.9
—
—
—
0
0
17
117
1.47
0.72
4.8
4.0
56.1
57.3
%
0.18
17
117
11
68
1.63
0.72
1.6
2.2
—
—
—
0
0
7
40
1.76
0.71
1.4
1.1
—
—
—
0
0
154
1392
1.14
0.71
3.6
3.8
—
—
—
0
0
150
1355
1.14
0.70
2.3
2.6
15.1
20.1
ng/l
0.85
54
551
14
93
1.52
0.70
1.1
1.0
—
—
—
0
0
17
118
1.45
0.70
1.4
1.2
2.2
5.6
u/ml
—
9
50
10
61
1.65
0.69
1.5
1.3
—
—
—
0
0
5
28
1.79
0.66
1.2
1.1
33.6
32.0
pg
—
5
28
110
977
1.15
0.66
1.6
1.5
—
—
—
0
0
7
44
1.60
0.65
1.0
1.2
—
—
—
0
0
18
129
1.41
0.64
1.1
1.0
0.1
0.4
u/ml
—
5
25
5
29
1.73
0.64
1.8
3.1
—
—
—
0
0
19
138
1.39
0.63
1.2
1.1
0.8
4.3
u/ml
—
8
55
66
565
1.19
0.62
1.2
1.2
—
—
—
0
0
6
103
0.58
0.62
4.7
3.8
—
—
—
0
0
113
1010
1.14
0.62
1.9
2.1
6009.2
4666.5
umol/l
0.12
100
903
0
21
0.00
0.60
0.0
2.2
—
8.2
—
0
15
18
131
1.38
0.59
1.3
1.4
324.1
316.0
ug/g
—
8
71
27
210
1.30
0.59
1.9
2.1
3.2
4.8
iu/l
0.72
14
89
131
1188
1.13
0.58
1.6
1.6
1.3
1.3
mmol/l
0.03
115
1045
99
883
1.14
0.57
1.5
1.5
423.5
43401445.2
pmol/l
1.57
88
788
58
496
1.19
0.57
1.4
1.3
—
—
—
0
0
63
543
1.18
0.56
1.8
1.7
—
—
—
0
0
6
37
1.63
0.55
1.3
1.5
94.5
91.4
%
—
6
37
9
60
1.51
0.54
1.1
1.8
—
—
—
0
0
9
60
1.51
0.54
1.1
1.1
201.6
199.1
mg/l
—
9
50
16
117
1.38
0.52
1.2
1.4
—
—
—
0
0
16
117
1.38
0.52
1.1
1.3
—
—
—
0
0
58
501
1.17
0.51
1.5
1.3
—
—
—
0
0
20
153
1.32
0.51
1.2
1.1
0.4
4.3
u/ml
—
8
55
23
181
1.28
0.48
1.2
1.1
0.2
2.1
u/ml
—
7
41
32
263
1.23
0.48
2.3
3.6
67.3
69.4
ng/l
0.09
27
240
31
254
1.23
0.48
3.6
6.7
96.8
96.2
%
0.29
31
248
7
48
1.46
0.47
2.0
3.1
—
—
—
0
0
50
431
1.17
0.46
1.3
1.7
—
—
—
0
0
43
366
1.19
0.46
1.3
1.7
—
—
—
0
0
17
129
1.33
0.46
3.2
1.6
—
—
—
0
0
7
49
1.43
0.46
1.0
1.2
—
—
—
0
0
25
305
0.81
0.42
2.0
3.1
—
—
—
0
0
91
826
1.12
0.42
1.5
1.4
760.0
584.2
titre
0.22
16
165
8
57
1.41
0.42
1.8
2.2
—
—
—
0
0
0
17
0.00
0.40
0.0
1.2
—
—
—
0
0
126
1167
1.10
0.40
2.2
2.9
8.1
7.9
mmol/l
0.13
113
998
53
467
1.15
0.39
1.3
1.7
—
—
—
0
0
11
80
1.38
0.38
2.5
2.1
—
—
—
0
0
53
468
1.14
0.38
1.3
1.7
—
—
—
0
0
5
36
1.39
0.38
1.0
1.0
—
—
—
0
0
5
36
1.39
0.38
1.0
1.1
—
—
—
0
0
22
179
1.24
0.37
3.5
4.4
24.9
24.9
mmol/l
0.01
22
179
37
318
1.17
0.37
1.1
1.1
—
—
—
0
0
53
470
1.14
0.36
1.3
1.7
—
—
—
0
0
11
81
1.36
0.36
1.2
1.0
—
—
—
0
0
52
461
1.14
0.36
1.3
1.7
—
—
—
0
0
13
99
1.32
0.35
1.1
1.2
—
—
—
0
0
21
173
1.22
0.33
1.1
1.3
—
—
—
0
0
6
46
1.31
0.33
1.2
1.6
—
—
—
0
0
6
47
1.28
0.32
1.7
1.6
5.0
5.1
mmol/l
—
6
47
11
83
1.33
0.32
1.0
1.5
42.4
39.2
g/l
1.77
11
77
22
262
0.83
0.31
6.0
4.8
1.2
1.2
mmol/l
0.11
22
252
7
53
1.32
0.31
1.6
1.4
—
—
—
0
0
10
75
1.34
0.30
1.4
1.5
—
69.0
—
0
5
20
166
1.21
0.30
1.4
1.8
—
—
—
0
0
7
55
1.28
0.30
1.3
1.7
—
—
—
0
0
14
174
0.80
0.30
1.6
2.3
13.5
4.9
ug/l
0.35
14
153
19
157
1.22
0.30
3.3
4.8
—
—
—
0
0
98
915
1.08
0.28
3.1
4.0
8.2
10.5
mg/mmol
0.20
62
567
60
547
1.11
0.28
1.4
1.3
—
—
—
0
0
30
261
1.16
0.28
2.3
2.8
2.0
1.9
mmol/l
0.02
25
204
18
149
1.21
0.28
4.3
7.9
—
—
—
0
0
21
178
1.19
0.26
1.3
1.1
—
—
—
0
0
51
463
1.11
0.26
1.5
1.4
—
—
—
0
0
52
473
1.11
0.26
1.6
1.5
—
—
—
0
0
30
263
1.15
0.26
2.3
2.8
5.9
5.8
kpa
0.16
30
258
5
74
0.67
0.26
2.0
5.9
294.4
383.1
umol/l
—
5
65
24
207
1.17
0.25
3.3
2.2
—
—
—
0
0
194
1866
1.06
0.24
1.8
1.8
—
—
—
0
0
5
41
1.22
0.22
1.2
1.3
—
63.5
—
0
6
0
11
0.00
0.21
0.0
2.3
—
—
—
0
0
50
460
1.09
0.21
1.5
1.4
—
—
—
0
0
15
126
1.20
0.21
1.1
1.2
312.6
233.2
u/ml
—
7
79
5
43
1.16
0.21
1.6
1.9
62.8
62.5
%
—
5
43
11
89
1.24
0.21
1.3
2.2
1.0
0.9
nmol/l
0.34
11
75
6
48
1.25
0.20
1.2
1.3
—
—
—
0
0
6
50
1.20
0.19
3.5
2.2
—
—
—
0
0
48
518
0.92
0.19
1.4
1.4
—
—
—
0
0
10
121
0.82
0.18
1.2
1.3
—
—
—
0
0
45
418
1.08
0.16
2.2
2.3
9.7
19.2
au/ml
—
7
30
16
139
1.15
0.16
1.1
1.3
339.2
413.8
mg/l
0.97
16
131
88
839
1.06
0.16
1.3
1.3
—
—
—
0
0
32
349
0.91
0.16
4.6
4.0
0.4
0.7
%
—
7
60
88
921
0.95
0.15
2.3
2.1
—
—
—
0
0
13
150
0.86
0.14
1.5
1.1
—
—
—
0
0
13
150
0.86
0.14
1.5
1.1
—
—
—
0
0
500
5045
0.96
0.14
3.5
3.3
4.8
4.8
mmol/l
0.52
478
4806
18
160
1.13
0.14
1.7
1.4
—
—
—
0
0
11
128
0.86
0.13
1.1
1.2
3.6
3.7
mmol/l
0.30
11
119
19
170
1.12
0.13
4.1
6.3
24.7
24.8
mmol/l
0.05
19
161
14
159
0.88
0.13
1.5
1.3
—
—
—
0
0
32
344
0.93
0.12
4.8
4.3
0.0
0.1
%
—
6
62
27
249
1.09
0.12
4.1
6.7
120.9
121.3
g/l
0.04
27
242
29
269
1.08
0.11
1.3
1.4
—
—
—
0
0
10
86
1.17
0.11
1.0
1.0
—
—
—
0
0
35
372
0.94
0.10
4.6
4.2
0.9
1.0
%
—
8
80
499
5025
0.97
0.10
3.5
3.3
1.6
1.5
mmol/l
1.13
474
4771
5
45
1.11
0.10
1.6
1.7
0.9
1.0
g/l
—
5
45
29
272
1.07
0.09
2.4
2.9
—
—
—
0
0
6
54
1.11
0.09
1.3
1.3
—
—
—
0
0
6
54
1.11
0.09
1.0
1.4
—
—
—
0
0
483
4798
1.03
0.09
3.1
3.0
1.1
1.2
mmol/l
0.22
458
4551
7
65
1.08
0.08
2.3
1.5
—
—
—
0
0
12
132
0.91
0.06
1.2
1.1
—
—
—
0
0
31
295
1.05
0.06
5.5
6.4
5.2
5.1
kpa
0.07
31
282
31
295
1.05
0.06
5.5
6.4
13.1
13.1
kpa
0.02
31
283
29
305
0.95
0.06
8.3
10.6
1.3
1.1
inr
—
5
57
90
880
1.03
0.06
2.6
3.3
651.5
377.1
mg/l
0.18
61
560
34
355
0.96
0.06
4.6
4.3
0.4
0.1
%
—
7
72
31
296
1.05
0.06
5.5
6.4
1.1
1.3
mmol/l
0.07
24
227
35
336
1.04
0.05
1.4
2.1
—
—
—
0
0
19
179
1.06
0.05
1.8
1.9
—
—
—
0
0
214
2160
0.99
0.04
2.3
2.2
—
—
—
0
0
74
755
0.98
0.04
2.1
2.2
4005.2
5489.4
u/l
0.26
32
328
168
1665
1.01
0.03
1.9
1.7
—
—
—
0
0
13
123
1.06
0.01
1.8
3.2
—
—
—
0
0
42
412
1.02
0.01
1.4
1.4
244.6
247.0
miu/ml
0.02
23
217
10
106
0.94
0.01
1.1
1.4
29.5
33.5
nmol/l
—
10
92
12
114
1.05
0.00
3.0
4.8
1.6
1.6
%
0.02
12
108
13
125
1.04
0.00
4.0
7.5
23.9
24.2
mmol/l
0.08
13
119
13
134
0.97
0.00
1.5
3.0
0.2
0.3
g/l
—
5
47
21
213
0.99
0.00
1.4
1.8
—
—
—
0
0
509
5094
1.00
0.00
3.7
3.5
2.9
2.9
mmol/l
0.19
482
4808
0
5
0.00
0.00
0.0
2.8
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
1.9
—
49.6
—
0
8
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
0.00
0.0
1.6
—
14.2
—
0
5
0
5
0.00
0.00
0.0
1.6
—
—
—
0
0
0
5
0.00
0.00
0.0
1.4
—
1.4
—
0
5
0
5
0.00
0.00
0.0
1.6
—
—
—
0
0
0
5
0.00
0.00
0.0
5.6
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
8
89
0.90
0.00
1.6
1.8
432.9
155.5
ug/l
—
8
75
0
9
0.00
0.00
0.0
3.7
—
25.5
—
0
9
0
6
0.00
0.00
0.0
1.3
—
1.3
—
0
6
0
6
0.00
0.00
0.0
1.3
—
—
—
0
0
0
6
0.00
0.00
0.0
8.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
34.5
—
0
6
5
55
0.91
0.00
1.2
1.2
—
—
—
0
0
0
7
0.00
0.00
0.0
1.1
—
18.1
—
0
7
8
79
1.01
0.00
3.1
2.6
—
—
—
0
0

Mortality – FinRegistry

↥

Association

Association between endpoint Q17_CONGEN_MALFO_BREAST and mortality.

Females

No data

Males

No data

Mortality risk

Mortality risk for people of age

years, who have Q17_CONGEN_MALFO_BREAST.

N-year risk Females Males
1 No data No data
5 No data No data
10 No data No data
15 No data No data
20 No data No data

Relationships between endpoints

↥

Index endpoint: Q17_CONGEN_MALFO_BREAST – Congenital malformations of breast

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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