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Congenital malformations of breast

DOID EFO Endpoint Browser PheWeb

Q17_CONGEN_MALFO_BREAST

Endpoint definition

↥

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

519972

1. Apply sex-specific rule

None

519972

2. Check conditions

None

519972

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — Q83
  • Cause of death: ICD-10 — Q83

2 out of 7 registries used, show all original rules.

677

4. Check minimum number of events

None

677

5. Include endpoints

None

677

6. Filter based on genotype QC (FinnGen only)

649

Control definitions (FinnGen only)

Control exclude
Q17_OTHER_CONGEN_MALFO

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF4
Parent code in ICD-10
Q8
Name in latin
Malformationes congenitae mammae

Case counts by codes

↥

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 4263 4107 135
Only index persons 4143 4029 114
Unadjusted period prevalence (%)
Whole population 0.11 0.12 0.00
Only index persons 0.14 0.15 0.00
Median age at first event (years)
Whole population 29.72 30.19 14.84
Only index persons 29.83 30.23 15.89

-FinnGen-

Key figures

All Female Male
Number of individuals 649 638 11
Unadjusted period prevalence (%) 0.22 0.23 0.01
Median age at first event (years) 33.37 33.19 44.00

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
677
Matched controls
6770
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
Q83.8
ICD-10 Finland
Other congenital malformations of breast
2203.6
307.7
336
*
Q83.1
ICD-10 Finland
Accessory breast
+∞
279.1
248
*
HAD40
NOMESCO Finland
Mastopexy
82.3
149.8
80
11
HAD10
NOMESCO Finland
Augmentation of breast using prosthesis
227.1
128.6
129
7
HAD99
NOMESCO Finland
Other plastic operation on breast
44.3
124.6
75
19
ZZF00
NOMESCO Finland
Graft of adipose tissue
30.9
115.2
77
28
HAC30
NOMESCO Finland
Excision of supernumerary mammary gland or mamilla
1101.2
99.7
95
*
Q83.9
ICD-10 Finland
Congenital malformation of breast, unspecified
+∞
78.7
74
*
HAE99
NOMESCO Finland
Other reconstruction of breast
25.0
71.3
51
22
HA1AE
NOMESCO Finland
Ultrasound examination of mammary glands
5.3
54.5
124
274
Q83.3
ICD-10 Finland
Accessory nipple
+∞
48.5
46
*
HAD30
NOMESCO Finland
Reduction mammoplasty with transposition of areola
6.1
46.2
86
157
N64.8
ICD-10 Finland
Other specified disorders of breast
17.5
42.1
35
21
QBE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin of trunk
5.1
34.8
79
172
HAD50
NOMESCO Finland
Removal of prosthetic implant from breast
48.3
34.1
41
9
ZXA10
NOMESCO Finland
Bilateral
3.3
33.9
157
570
N62
ICD-10 Finland
Hypertrophy of breast
4.9
32.6
77
173
ZXE10
NOMESCO Finland
More than one and less than three hours
2.6
30.7
269
1367
HAD00
NOMESCO Finland
Augmentation mammoplasty
108.2
28.9
31
*
N64.9
ICD-10 Finland
Disorder of breast, unspecified
9.4
28.8
35
39
WX404
NOMESCO Finland
Intravenous generell anesthesy
2.7
27.2
194
883
HA1AA
NOMESCO Finland
X-ray mammography
3.8
26.0
85
244
T85.4
ICD-10 Finland
Mechanical complication of breast prosthesis and implant
93.7
24.8
27
*
HAB00
NOMESCO Finland
Excision of lesion of mammary gland
5.1
22.3
48
99
ZXD10
NOMESCO Finland
Scheduled procedure
2.3
22.2
271
1548
WX408
NOMESCO Finland
General anesthesy, balanced
2.3
19.1
189
979
HAD60
NOMESCO Finland
Replacement of prosthetic implant in breast
72.0
18.8
21
*
N64.2
ICD-10 Finland
Atrophy of breast
54.1
18.0
21
*
QBJ00
NOMESCO Finland
Liposuction in trunk
19.3
17.4
26
14
WX402
NOMESCO Finland
General anaesthesia
2.2
17.1
177
929
N64.5
ICD-10 Finland
Other signs and symptoms in breast
4.2
16.7
45
112
Z42.1
ICD-10 Finland
Follow-up care involving plastic surgery of breast
17.7
15.7
24
14
ZXA05
NOMESCO Finland
Left side
2.3
14.9
129
626
THW99
NOMESCO Finland
Other minor procedure in surgery of mammary gland
5.5
13.8
27
51
Q83.0
ICD-10 Finland
Congenital absence of breast with absent nipple
+∞
13.6
13
*
6114A
ICD-9 Finland
Other disorders of breast, Atrophy of breast
51.0
12.9
15
*
9729
FHL
Other measure in this category
28.5
10.8
14
5
HAB99
NOMESCO Finland
Other partial excision of mammary gland
4.6
10.6
25
56
Q83
ICD-10 Finland
Congenital malformations of breast
+∞
10.4
10
*
QB2S1
NOMESCO Finland
Photography of skin or subcutaneous tissue in chest
9.8
10.3
20
21
QBB10
NOMESCO Finland
Major dressing of wound of skin of trunk
3.3
10.3
39
123
HAE00
NOMESCO Finland
Reconstruction of breast using prosthesis
23.8
10.3
14
6
ZXE00
NOMESCO Finland
One hour or less
1.7
9.9
274
1933
Y83
ICD-10 Finland
Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
3.0
9.8
45
159
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.7
9.5
294
2131
ZXA00
NOMESCO Finland
Right side
1.9
9.3
123
694
R4110
NOMESCO Finland
Physiotherapy
1.8
9.3
159
976
HAE10
NOMESCO Finland
Reconstruction of breast using graft or flap
4.9
9.1
20
42
LC2BE
NOMESCO Finland
Transvaginal ultrasound examination of uterus, parametria and lower abdomen
1.6
9.0
309
2290
N63
ICD-10 Finland
Unspecified lump in breast
2.3
8.9
74
350
N02BE01
ATC
paracetamol; systemic, rectal
2.0
8.8
591
5222
P01AB01
ATC
metronidazole; oral, rectal
1.6
8.4
297
2205
QBE30
NOMESCO Finland
Excision and repair of surgical scar in trunk
11.9
8.1
14
12
N64.4
ICD-10 Finland
Mastodynia
2.7
8.1
45
177
M03AX01
ATC
botulinum toxin; parenteral
3.8
8.0
24
65
Z2221
NOMESCO Finland
Medical doctor
1.7
7.9
200
1361
J01DB01
ATC
cefalexin; oral
1.9
7.8
571
5038
C05AA08
ATC
fluocortolone; rectal, topical
2.1
7.8
75
376
J02AC01
ATC
fluconazole; systemic
1.6
7.6
338
2628
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.6
7.5
272
2016
NHG80
NOMESCO Finland
Fusion of first tarsometatarsal joint
3.8
7.4
22
59
WX702
NOMESCO Finland
Supraglottic ventilation device
2.6
7.3
43
174
Z3226
NOMESCO Finland
Physiotherapist
1.8
7.1
108
635
L90.5
ICD-10 Finland
Scar conditions and fibrosis of skin
6.1
7.1
18
30
QBE20
NOMESCO Finland
Excision and repair of scar or web of skin of trunk
6.4
7.0
17
27
R51
ICD-10 Finland
Headache
2.1
7.0
63
309
ZXD20
NOMESCO Finland
Day surgery
1.9
6.9
85
467
R00.2
ICD-10 Finland
Palpitations
2.1
6.9
66
331
N02AJ06
ATC
codeine and paracetamol; systemic
1.5
6.8
275
2079
HA1CG
NOMESCO Finland
Extensive MRI examination of mammary gland with high intensity magnet
4.0
6.7
19
49
X21
ICPC
Breast sympt/compl female other
2.9
6.7
30
105
C07AA05
ATC
propranolol; systemic
1.6
6.7
168
1137
J01AA02
ATC
doxycycline; systemic
1.6
6.5
464
3946
M03BC51
ATC
orphenadrine, combinations; systemic
1.6
6.4
179
1243
N06CA01
ATC
amitriptyline and psycholeptics; systemic
2.1
6.3
58
286
Q79.8
ICD-10 Finland
Other congenital malformations of musculoskeletal system
+∞
6.3
6
*
QBJ99
NOMESCO Finland
Other aesthetic correction of skin of trunk
26.9
6.2
8
*
M01AE03
ATC
ketoprofen; systemic, rectal
1.6
6.1
184
1295
T81.8
ICD-10 Finland
Other complications of procedures, not elsewhere classified
4.2
6.1
16
39
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
1.9
6.1
76
419

LabWAS

↥
OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
186
1140
1.87
11.11
2.8
3.0
100.41
98.15
%
0.74
181
1100
125
678
2.03
10.66
1.3
1.2
—
—
—
0
0
462
3769
1.71
9.40
6.3
5.8
69.99
71.73
u/l
0.57
434
3545
245
1719
1.67
8.79
3.6
4.0
37.32
37.14
g/l
0.21
226
1608
309
2321
1.61
8.32
2.1
1.9
—
—
—
0
0
238
1708
1.61
7.57
1.8
1.8
—
—
—
0
0
473
4003
1.60
7.17
3.9
3.5
8.62
9.00
mm/h
0.38
440
3743
584
5250
1.82
6.70
13.7
11.2
14.09
14.04
%
0.10
576
5162
352
2815
1.52
6.67
2.5
2.4
—
—
—
0
0
201
1433
1.57
6.38
2.4
2.2
57.56
56.03
u/l
0.19
183
1325
595
5401
1.84
6.31
9.4
8.7
3.87
3.88
mmol/l
0.64
580
5214
592
5385
1.79
5.96
9.4
8.6
139.42
139.52
mmol/l
0.56
580
5213
302
2381
1.48
5.88
4.7
4.6
9.34
9.41
umol/l
0.05
280
2221
620
5734
1.97
5.73
10.9
9.3
18.17
17.99
mg/l
0.05
480
4361
384
3205
1.46
5.41
2.7
2.6
—
—
—
0
0
16
34
4.79
5.33
1.1
1.0
—
—
—
0
0
332
2706
1.45
5.24
6.0
5.0
30.77
29.95
%
0.89
310
2557
306
2457
1.45
5.23
6.0
5.1
0.69
0.66
%
0.44
281
2289
290
2306
1.45
5.22
2.5
2.2
72.78
73.55
nmol/l
0.18
265
2140
328
2671
1.44
5.19
5.7
4.8
55.37
56.36
%
1.00
305
2515
317
2568
1.44
5.14
6.0
5.0
2.79
2.64
%
0.51
294
2409
319
2588
1.44
5.13
6.3
5.2
7.70
7.74
%
0.09
297
2437
56
297
1.97
5.05
1.3
1.4
10.50
10.23
u/l
0.06
40
246
257
2019
1.44
4.84
4.8
4.8
1.22
1.22
mmol/l
0.27
220
1689
99
637
1.65
4.70
1.4
1.4
20.31
24.05
iu/l
0.64
80
543
539
4879
1.51
4.50
4.4
4.3
14.24
14.25
pmol/l
0.00
504
4556
131
913
1.54
4.44
2.4
2.3
109.62
78.77
ug/g
0.75
100
703
669
6504
3.42
4.20
17.2
14.1
268.08
267.41
e9/l
0.10
657
6375
327
2731
1.38
4.15
5.7
5.1
0.04
0.04
e9/l
0.18
283
2424
326
2724
1.38
4.11
5.7
5.0
0.52
0.52
e9/l
0.03
283
2423
226
1778
1.41
4.08
4.0
4.2
1.22
1.22
mmol/l
0.36
205
1622
20
75
2.72
4.02
2.4
2.0
—
—
—
0
0
338
2850
1.37
3.99
6.1
5.3
0.18
0.17
e9/l
0.57
298
2557
37
185
2.06
3.96
1.3
1.2
—
—
—
0
0
669
6511
3.33
3.92
17.1
14.1
6.71
6.75
e9/l
0.20
656
6367
669
6510
3.34
3.91
17.1
14.1
4.44
4.46
e12/l
0.83
656
6375
336
2850
1.36
3.73
5.7
5.0
2.02
2.02
e9/l
0.03
300
2591
363
3128
1.35
3.57
8.0
7.4
3.72
3.94
e9/l
1.61
318
2759
216
1725
1.37
3.47
1.7
1.7
99.67
97.52
pmol/l
0.32
113
933
64
399
1.67
3.45
2.0
2.0
3.73
5.45
e9/l
1.21
54
358
93
635
1.54
3.45
1.2
1.1
—
—
—
0
0
41
224
1.88
3.45
1.7
1.5
0.88
0.39
nmol/l
0.43
32
189
158
1201
1.41
3.40
3.3
3.2
7.40
7.40
ph
0.24
29
230
82
546
1.57
3.40
1.8
2.0
393.58
381.55
nmol/l
0.20
72
505
307
2595
1.33
3.38
6.2
5.3
—
—
—
0
0
640
6125
1.82
3.21
10.5
8.9
—
—
—
0
0
122
896
1.44
3.17
2.5
2.3
542.62
529.73
mosm/kgh2o
0.14
105
772
448
4021
1.34
3.16
4.5
3.7
—
—
—
0
0
43
247
1.79
3.11
1.7
1.6
—
—
—
0
0
623
5927
1.64
3.09
8.8
7.6
23.78
23.30
u/l
0.32
602
5745
36
196
1.88
3.08
2.1
1.9
21.10
20.63
s
0.39
30
163
445
4010
1.32
2.93
2.9
2.6
32.48
31.52
u/l
0.16
426
3838
127
959
1.40
2.82
2.3
2.3
8.73
10.70
e6/l
0.42
115
848
171
1360
1.34
2.75
2.9
2.6
503.16
77.37
e6/l
0.44
134
1014
289
2475
1.29
2.72
7.7
7.2
0.00
0.00
e9/l
1.35
229
2054
276
2354
1.29
2.67
2.6
2.8
5.99
5.88
ph
0.31
34
236
317
2753
1.28
2.66
3.4
3.6
5.87
6.17
mmol/l
2.69
292
2429
185
1501
1.32
2.58
2.7
2.8
2.35
2.35
mmol/l
0.43
170
1365
158
1253
1.34
2.58
2.8
2.5
—
—
—
0
0
18
81
2.26
2.56
2.7
2.2
—
—
—
0
0
666
6500
2.51
2.53
16.9
14.0
39.50
39.70
%
0.47
647
6201
155
1231
1.34
2.50
2.9
2.5
0.20
0.33
e6/l
0.50
120
905
56
368
1.57
2.50
2.8
2.2
—
—
—
0
0
76
535
1.47
2.47
2.1
2.2
23.85
23.98
%
0.02
67
447
86
621
1.44
2.45
1.9
1.7
—
—
—
0
0
583
5523
1.40
2.39
5.1
4.9
1.64
1.93
mu/l
0.70
554
5244
22
111
2.01
2.38
1.0
1.1
—
—
—
0
0
65
448
1.50
2.35
2.0
2.1
29.34
34.10
u/l
0.60
56
370
161
1298
1.32
2.33
6.4
5.7
—
—
—
0
0
115
883
1.36
2.31
4.0
3.2
—
—
—
0
0
199
1658
1.28
2.25
2.1
2.2
—
—
—
0
0
214
1800
1.28
2.24
3.3
2.9
81.81
52.74
e6/l
0.39
144
1120
91
678
1.40
2.20
3.1
2.7
67.21
355.89
ng/l
1.18
42
331
329
2918
1.25
2.17
4.3
4.2
0.01
0.00
estimate
0.42
71
627
191
1591
1.28
2.15
5.7
6.2
1.05
1.05
inr
0.07
67
575
378
3408
1.25
2.14
3.1
2.9
63.50
56.07
ug/l
0.91
356
3209
11
43
2.58
2.08
1.1
1.0
—
—
—
0
0
86
642
1.39
2.06
2.5
2.2
2.10
5.13
e6/l
4.56
40
318
13
56
2.35
2.06
1.2
1.3
—
—
—
0
0
330
2947
1.23
1.99
3.3
3.1
0.00
0.01
estimate
0.80
72
614
35
218
1.64
1.98
1.0
1.1
0.66
4.38
u/ml
—
9
40
43
282
1.56
1.98
3.2
3.8
11.53
6.42
ug/l
0.37
29
208
135
1094
1.29
1.87
1.3
1.3
2.32
10.75
u/ml
3.19
48
459
22
122
1.83
1.86
2.0
2.5
—
—
—
0
0
424
3904
1.23
1.85
4.5
3.8
51.40
539.55
e6/l
—
5
40
127
1026
1.29
1.80
2.4
2.6
—
—
—
0
0
89
684
1.35
1.80
1.9
2.3
2.42
2.41
mmol/l
0.23
76
590
324
2915
1.21
1.74
3.2
3.0
0.00
0.00
estimate
0.50
75
645
269
2379
1.22
1.71
2.2
2.1
—
—
—
0
0
75
567
1.36
1.69
3.6
3.2
—
—
—
0
0
73
550
1.37
1.68
1.8
1.9
28.81
29.24
s
0.42
73
534
535
5075
1.26
1.66
3.4
3.2
5.54
5.54
mmol/l
0.02
492
4744
39
264
1.51
1.59
1.1
1.1
—
—
—
0
0
6
20
3.02
1.58
2.0
2.5
0.26
0.17
e9/l
—
6
20
13
64
2.05
1.55
1.2
1.0
0.20
3.49
u/ml
—
5
22
478
4493
1.22
1.54
4.1
3.9
36.31
37.14
mmol/mol
1.70
452
4257
135
1121
1.26
1.54
1.4
1.3
14.58
24.42
iu/ml
1.57
50
371
49
351
1.43
1.52
1.3
1.3
—
—
—
0
0
79
613
1.33
1.52
2.1
2.1
2.45
2.49
g/l
0.31
71
554
7
27
2.61
1.52
1.7
1.9
44.46
45.90
%
—
7
27
151
1274
1.24
1.50
1.8
1.8
—
—
—
0
0
149
1256
1.24
1.49
1.9
1.7
0.89
0.76
mg/l
0.43
116
917
197
1710
1.21
1.49
1.4
1.3
1.05
1.97
u/ml
0.79
54
458
206
1800
1.21
1.45
2.8
2.8
34.38
26.61
u/l
0.64
196
1714
11
52
2.13
1.45
1.5
1.4
—
—
—
0
0
158
1345
1.23
1.44
2.2
2.0
2.50
2.65
mg/l
0.46
127
1147
5
16
3.14
1.44
1.8
1.7
—
—
—
0
0
51
373
1.40
1.43
1.2
1.2
—
—
—
0
0
87
691
1.30
1.42
2.1
2.1
14.94
14.79
umol/l
0.06
81
633
28
181
1.57
1.42
1.3
1.2
—
—
—
0
0
167
1437
1.22
1.37
1.5
1.4
2.10
2.03
g/l
0.27
102
896
13
68
1.93
1.34
1.2
1.3
—
—
—
0
0
16
90
1.80
1.34
1.4
1.6
—
—
—
0
0
9
43
2.11
1.30
1.1
1.1
—
—
—
0
0
8
34
2.37
1.29
1.1
1.1
—
—
—
0
0
58
442
1.34
1.28
1.3
1.3
—
—
—
0
0
50
373
1.37
1.26
2.7
3.0
—
—
—
0
0
40
287
1.42
1.26
1.2
1.2
—
—
—
0
0
5
19
2.64
1.22
1.0
1.1
—
—
—
0
0
6
26
2.32
1.19
1.2
1.5
176.50
169.79
mmol/24h
—
6
26
134
1145
1.21
1.18
1.4
1.5
—
—
—
0
0
17
102
1.68
1.17
2.8
3.3
19.48
26.72
mg/l
—
9
66
115
969
1.23
1.17
1.3
1.4
20.11
20.85
nmol/l
0.25
98
850
5
20
2.51
1.15
1.0
1.2
—
—
—
0
0
251
2272
1.17
1.14
1.9
1.8
—
—
—
0
0
73
586
1.28
1.13
1.7
1.5
—
—
—
0
0
27
184
1.49
1.12
1.1
1.1
1.49
0.85
u/ml
0.46
11
81
13
73
1.80
1.11
1.2
1.0
0.53
1.36
u/ml
—
5
19
53
409
1.32
1.10
1.4
1.2
—
—
—
0
0
144
1249
1.19
1.09
2.7
3.0
—
—
—
0
0
31
219
1.44
1.09
1.2
1.1
2.18
3.42
u/ml
0.41
17
115
7
32
2.20
1.08
2.1
3.1
—
—
—
0
0
28
195
1.45
1.06
2.0
2.1
—
—
—
0
0
68
548
1.27
1.03
2.2
2.1
6.39
5.00
umol/l
0.31
50
443
7
34
2.07
1.03
1.0
1.1
1195.71
1573.59
miu/ml
—
7
34
35
256
1.39
1.03
2.3
1.7
—
—
—
0
0
9
48
1.89
1.00
1.4
1.5
275.57
453.83
pmol/l
—
9
42
19
123
1.56
1.00
1.3
1.3
2.22
5.58
u/ml
—
9
52
18
115
1.58
1.00
2.3
2.6
—
—
—
0
0
77
633
1.24
1.00
1.5
1.4
—
—
—
0
0
198
1779
1.16
0.98
3.0
2.7
—
—
—
0
0
32
233
1.39
0.97
2.6
2.1
8.20
4.53
umol/l
0.54
25
172
9
50
1.81
0.97
1.0
1.1
—
—
—
0
0
159
1406
1.17
0.97
2.3
2.5
14.52
19.90
ng/l
1.00
58
563
13
77
1.70
0.95
1.5
1.7
5237.75
12915.87
e6/l
—
8
60
60
482
1.27
0.95
2.9
3.6
4.51
4.63
pmol/l
0.49
54
429
176
1572
1.16
0.94
3.4
3.3
0.00
0.00
estimate
1.08
72
621
6
27
2.23
0.93
1.2
1.1
—
—
—
0
0
6
27
2.23
0.93
3.5
2.0
—
—
—
0
0
6
27
2.23
0.93
3.3
2.9
—
—
—
0
0
16
102
1.58
0.91
1.1
1.3
—
—
—
0
0
11
63
1.76
0.90
1.5
1.3
—
—
—
0
0
27
194
1.41
0.89
1.1
1.1
2.42
5.72
u/ml
1.03
13
104
6
29
2.08
0.89
1.8
3.8
—
—
—
0
0
8
42
1.92
0.88
1.4
1.2
—
—
—
0
0
31
229
1.37
0.88
5.0
6.3
—
—
—
0
0
29
215
1.36
0.82
3.0
2.1
62.90
71.38
e9/l
1.03
21
151
18
122
1.49
0.81
1.1
1.2
—
—
—
0
0
12
74
1.63
0.78
1.0
1.1
—
—
—
0
0
82
699
1.20
0.78
1.1
1.2
92.61
157.99
iu/ml
1.36
28
297
75
634
1.21
0.78
1.7
1.6
1393.76
1160.10
nmol/l
0.51
66
487
0
28
0.00
0.76
0.0
1.7
—
—
—
0
0
5
24
2.09
0.74
1.0
1.2
6.36
6.46
nmol/l
—
5
24
67
564
1.21
0.73
1.9
1.7
—
—
—
0
0
6
107
0.56
0.73
4.7
4.0
—
—
—
0
0
19
134
1.43
0.72
1.1
1.0
0.06
0.29
u/ml
—
6
39
139
1249
1.14
0.69
2.8
3.2
1.02
1.02
kg/l
0.10
21
177
15
102
1.48
0.68
5.1
3.1
1.42
1.24
mg/l
0.26
15
91
26
197
1.33
0.66
2.0
2.8
7.38
7.41
ph
—
5
25
18
128
1.42
0.66
1.0
1.0
1.43
2.57
u/ml
—
9
69
11
70
1.58
0.65
1.6
2.1
—
—
—
0
0
7
44
1.60
0.65
2.7
2.9
36514.29
41481.82
ug/l
—
7
44
17
120
1.43
0.65
4.2
3.5
3.91
4.26
e9/l
0.34
17
120
5
29
1.73
0.64
1.8
3.1
—
—
—
0
0
20
147
1.37
0.62
1.1
1.1
0.82
5.75
u/ml
—
8
62
5
30
1.67
0.61
1.2
1.1
33.60
31.77
pg
—
5
30
117
1049
1.14
0.61
1.9
2.1
5738.30
4459.64
umol/l
0.12
105
948
69
594
1.18
0.61
1.1
1.2
—
—
—
0
0
17
122
1.40
0.60
4.8
3.9
56.12
57.02
%
0.13
17
122
10
64
1.57
0.59
1.1
1.8
—
—
—
0
0
8
53
1.52
0.58
1.5
1.4
—
—
—
0
0
6
36
1.67
0.57
1.2
1.3
5.08
5.87
ug/l
—
6
30
14
99
1.42
0.54
1.1
1.0
—
—
—
0
0
114
1030
1.13
0.54
1.6
1.5
—
—
—
0
0
9
61
1.48
0.54
1.7
2.0
—
—
—
0
0
9
62
1.46
0.53
1.1
1.1
201.56
202.35
mg/l
—
9
52
102
917
1.13
0.53
1.5
1.5
430.12
41809719.67
pmol/l
1.57
90
818
6
40
1.50
0.51
1.3
1.4
94.52
91.77
%
—
6
40
27
215
1.27
0.51
1.9
2.1
3.24
4.69
iu/l
0.66
14
91
18
135
1.34
0.51
1.3
1.4
324.13
314.64
ug/g
—
8
72
32
261
1.24
0.50
3.6
6.6
96.77
96.24
%
0.26
32
255
21
162
1.31
0.50
1.1
1.1
0.41
4.59
u/ml
—
9
78
23
180
1.29
0.50
1.1
1.3
—
—
—
0
0
17
127
1.35
0.50
1.2
1.4
—
—
—
0
0
135
1239
1.11
0.50
1.6
1.6
1.32
1.32
mmol/l
0.02
118
1095
33
271
1.23
0.49
2.3
2.8
1.80
1.88
mmol/l
0.03
28
219
61
532
1.16
0.49
1.4
1.3
—
—
—
0
0
26
322
0.80
0.49
2.0
3.0
—
—
—
0
0
7
46
1.53
0.48
1.0
1.2
—
—
—
0
0
24
191
1.27
0.47
1.2
1.1
0.63
2.36
u/ml
1.78
12
97
33
273
1.22
0.47
2.3
2.8
5.92
5.83
kpa
0.16
33
267
7
50
1.40
0.45
2.0
3.2
—
—
—
0
0
60
527
1.15
0.45
1.5
1.3
—
—
—
0
0
17
130
1.32
0.44
1.1
1.2
301.56
233.43
u/ml
—
9
80
7
51
1.38
0.44
1.0
1.2
—
—
—
0
0
95
862
1.12
0.44
1.4
1.4
751.11
572.11
titre
0.25
18
175
52
453
1.16
0.43
1.3
1.7
—
—
—
0
0
45
388
1.17
0.42
1.3
1.7
—
—
—
0
0
8
58
1.38
0.41
1.3
1.7
—
—
—
0
0
39
333
1.18
0.41
1.1
1.1
—
—
—
0
0
5
33
1.52
0.41
1.8
1.4
18941.60
11365.21
e6/l
—
5
24
56
493
1.15
0.41
1.4
1.7
—
—
—
0
0
14
183
0.76
0.41
1.6
2.2
13.46
5.25
ug/l
0.34
14
159
0
17
0.00
0.40
0.0
1.2
—
—
—
0
0
56
495
1.14
0.39
1.4
1.7
—
—
—
0
0
131
1217
1.09
0.39
2.2
3.0
7.97
7.87
mmol/l
0.08
119
1062
5
35
1.43
0.39
1.0
1.4
—
—
—
0
0
209
1984
1.08
0.38
1.8
1.8
—
—
—
0
0
56
497
1.14
0.38
1.4
1.7
—
—
—
0
0
55
488
1.14
0.37
1.4
1.7
—
—
—
0
0
21
171
1.24
0.36
1.7
1.5
—
—
—
0
0
18
144
1.26
0.35
1.1
1.3
343.33
419.45
mg/l
1.05
18
135
20
163
1.23
0.34
3.2
4.7
—
—
—
0
0
11
82
1.35
0.34
1.2
1.0
—
—
—
0
0
13
100
1.31
0.33
1.4
1.5
10.12
10.04
g/l
0.02
13
94
32
275
1.17
0.33
2.3
3.5
67.33
68.85
ng/l
0.07
27
250
6
46
1.31
0.33
1.2
1.6
—
—
—
0
0
6
46
1.31
0.33
1.5
1.8
59.50
62.00
%
—
6
46
14
110
1.28
0.32
1.1
1.2
—
—
—
0
0
7
54
1.30
0.30
1.0
1.4
—
—
—
0
0
32
278
1.16
0.30
1.3
1.4
—
—
—
0
0
10
130
0.77
0.29
1.2
1.2
—
—
—
0
0
32
364
0.87
0.28
2.9
5.0
106.13
104.84
mmol/l
1.58
32
364
101
946
1.08
0.27
3.0
3.8
8.56
10.10
mg/mmol
0.13
63
595
22
187
1.18
0.27
1.3
1.1
—
—
—
0
0
185
1775
1.06
0.25
1.9
1.7
—
—
—
0
0
18
151
1.20
0.25
4.3
7.6
—
—
—
0
0
11
87
1.27
0.24
1.0
1.5
42.40
39.19
g/l
1.76
11
82
62
572
1.09
0.24
1.4
1.3
—
—
—
0
0
48
437
1.11
0.24
2.2
2.3
10.09
20.84
au/ml
—
8
42
20
171
1.17
0.23
1.4
1.8
—
—
—
0
0
5
38
1.32
0.23
1.0
1.1
—
—
—
0
0
5
39
1.28
0.23
1.0
1.0
—
—
—
0
0
18
153
1.18
0.22
4.3
1.9
—
—
—
0
0
5
41
1.22
0.22
1.2
1.3
63.60
68.15
umol/l
—
5
41
0
11
0.00
0.21
0.0
2.3
—
—
—
0
0
22
192
1.15
0.21
1.7
1.8
—
—
—
0
0
10
80
1.25
0.20
1.4
1.5
—
67.02
—
0
6
6
49
1.23
0.20
1.7
1.6
5.00
5.15
mmol/l
—
6
49
507
5009
1.05
0.19
3.1
3.0
1.14
1.16
mmol/l
0.27
481
4758
6
51
1.18
0.19
3.3
2.2
—
—
—
0
0
11
90
1.23
0.19
2.9
1.8
6.42
5.17
mmol/24h
0.50
11
79
50
537
0.93
0.17
1.4
1.4
—
—
—
0
0
11
91
1.21
0.17
1.3
2.2
1.02
0.88
nmol/l
0.33
11
77
53
495
1.08
0.17
1.5
1.4
—
—
—
0
0
5
68
0.73
0.17
1.2
1.2
—
—
—
0
0
54
506
1.07
0.16
1.6
1.5
—
—
—
0
0
24
216
1.12
0.15
3.3
2.1
—
—
—
0
0
6
77
0.78
0.15
2.3
5.8
294.00
386.27
umol/l
—
6
67
52
492
1.06
0.12
1.5
1.4
—
—
—
0
0
25
272
0.92
0.12
5.8
4.7
1.30
1.20
mmol/l
0.32
25
263
13
114
1.14
0.12
2.8
4.6
1.55
1.61
%
0.13
13
108
10
115
0.87
0.10
1.1
1.4
29.49
32.70
nmol/l
—
10
101
91
882
1.04
0.09
1.3
1.3
—
—
—
0
0
5
47
1.06
0.09
1.6
1.7
0.92
0.99
g/l
—
5
47
6
55
1.09
0.09
1.2
1.3
—
—
—
0
0
6
56
1.07
0.08
1.7
1.6
—
—
—
0
0
34
359
0.94
0.08
4.5
4.0
0.43
0.81
%
—
7
85
6
57
1.05
0.08
1.2
1.2
—
—
—
0
0
19
176
1.08
0.07
4.1
6.1
24.73
24.69
mmol/l
0.02
19
168
8
74
1.08
0.07
2.9
1.5
—
—
—
0
0
534
5313
1.02
0.07
3.7
3.5
2.89
2.86
mmol/l
0.29
508
5037
34
357
0.95
0.07
4.7
4.3
0.00
0.14
%
—
6
72
32
304
1.06
0.07
5.4
6.2
13.03
13.20
kpa
0.07
32
291
32
304
1.06
0.07
5.4
6.2
5.16
5.08
kpa
0.11
32
290
93
908
1.03
0.07
2.6
3.3
645.63
358.66
mg/l
0.19
62
590
8
93
0.86
0.06
1.6
2.1
432.88
150.41
ug/l
—
8
79
12
132
0.91
0.06
1.1
1.2
3.57
3.69
mmol/l
0.27
12
122
13
141
0.92
0.05
2.5
2.5
25.26
24.91
mmol/l
0.14
13
136
37
356
1.04
0.05
1.5
2.2
—
—
—
0
0
37
383
0.96
0.04
4.5
4.2
0.89
1.01
%
—
9
98
15
140
1.07
0.04
1.4
1.1
—
—
—
0
0
525
5262
0.99
0.02
3.5
3.3
4.83
4.78
mmol/l
0.56
502
5027
10
93
1.08
0.02
1.0
1.0
—
—
—
0
0
16
167
0.96
0.01
1.5
1.3
—
—
—
0
0
36
367
0.98
0.01
4.5
4.3
0.43
0.07
%
—
7
81
224
2248
0.99
0.01
2.3
2.2
—
—
—
0
0
13
136
0.96
0.00
1.5
3.0
0.21
0.32
g/l
—
5
49
15
156
0.96
0.00
1.5
1.1
—
—
—
0
0
15
156
0.96
0.00
1.5
1.1
—
—
—
0
0
31
305
1.02
0.00
5.5
6.2
1.12
1.27
mmol/l
0.05
24
235
13
128
1.02
0.00
4.0
7.4
23.92
24.21
mmol/l
0.09
13
123
22
222
0.99
0.00
1.5
1.9
—
—
—
0
0
524
5243
1.00
0.00
3.4
3.3
1.58
1.55
mmol/l
1.16
498
4992
81
812
1.00
0.00
2.1
2.2
6370.38
5349.49
u/l
0.11
37
351
43
431
1.00
0.00
1.3
1.3
244.56
248.12
miu/ml
0.03
23
229
0
6
0.00
0.00
0.0
1.3
—
1.34
—
0
6
0
6
0.00
0.00
0.0
8.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
34.48
—
0
6
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
0.00
0.0
1.5
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.4
—
1.44
—
0
5
0
5
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
5
0.00
-0.00
0.0
2.8
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.9
—
49.63
—
0
8
8
79
1.01
-0.00
3.1
2.6
—
—
—
0
0
5
58
0.86
-0.00
3.0
2.0
10.46
10.89
u/ml
—
5
58
13
130
1.00
-0.00
1.8
3.1
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
3.9
—
24.85
—
0
8
0
5
0.00
-0.00
0.0
1.6
—
14.24
—
0
5
96
960
1.00
-0.00
2.3
2.1
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.1
—
18.01
—
0
8
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0

Mortality – FinRegistry

↥

Association

Association between endpoint Q17_CONGEN_MALFO_BREAST and mortality.

Females

No data

Males

No data

Mortality risk

Mortality risk for people of age

years, who have Q17_CONGEN_MALFO_BREAST.

N-year risk Females Males
1 No data No data
5 No data No data
10 No data No data
15 No data No data
20 No data No data

Relationships between endpoints

↥

Index endpoint: Q17_CONGEN_MALFO_BREAST – Congenital malformations of breast

GWS hits: 1

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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