No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleNone |
520210 |
2. Check conditionsNone |
520210 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
795 |
4. Check minimum number of eventsNone |
795 |
5. Include endpointsNone |
795 |
6. Filter based on genotype QC (FinnGen only) |
795 |
Control definitions (FinnGen only)
- Control exclude
- K11_INTESTOTH
Extra metadata
- Level in the ICD hierarchy
- 4
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- K56
- Name in latin
- Invaginatio intestini
Similar endpoints
↥List of similar endpoints to
Intussusception
based on the number of shared cases.
Similar with more cases:
- Paralytic ileus and intestinal obstruction
- Other diseases of intestines
- Gastrointestinal diseases
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 5617 | 3736 | 1861 |
| Only index persons | 4964 | 3463 | 1501 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.09 | 0.11 | 0.05 |
| Only index persons | 0.11 | 0.13 | 0.06 |
| Median age at first event (years) | |||
| Whole population | 50.22 | 60.81 | 28.73 |
| Only index persons | 50.58 | 60.78 | 27.05 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 795 | 621 | 174 |
| Unadjusted period prevalence (%) | 0.18 | 0.21 | 0.08 |
| Median age at first event (years) | 56.62 | 58.39 | 50.29 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
No data
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 704
- Matched controls
- 7040
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
K56.1
ICD-10 Finland
Intussusception
+∞
323.0
607
*
JGC01
NOMESCO Finland
Laparoscopic rectopexy
838.2
247.2
229
*
N81.6
ICD-10 Finland
Rectocele
27.6
225.7
327
214
R15
ICD-10 Finland
Faecal incontinence
51.3
143.3
172
44
K59.01
ICD-10 Finland
Constipation outlet obstruction type
1649.3
142.8
134
*
XJH00
NOMESCO Finland
Transanal ultrasonography
28.1
129.1
180
85
UJF32
NOMESCO Finland
Coloscopy
8.9
124.9
317
591
JG1JB
NOMESCO Finland
Defekography with X-ray
238.0
118.6
119
6
A06AC01
ATC
ispaghula (psylla seeds); oral
6.8
105.5
337
837
K57.3
ICD-10 Finland
Diverticular disease of large intestine without perforation or abscess
19.8
90.7
141
88
N81.5
ICD-10 Finland
Vaginal enterocele
27.5
82.1
114
49
K59.09
ICD-10 Finland
Constipation, unspecified
28.5
79.3
109
45
RD211
NOMESCO Finland
NA
12.3
67.6
128
125
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
4.2
66.0
348
1323
K56.6
ICD-10 Finland
Other and unspecified intestinal obstruction
361.0
65.6
65
*
K62.3
ICD-10 Finland
Rectal prolapse
348.3
63.5
63
*
UJH02
NOMESCO Finland
Anoscopy
19.5
59.1
91
53
56000
ICD-8 Finland
Intestinal obstruction without mention of hernia, Intussusception
+∞
52.8
50
*
XJH10
NOMESCO Finland
Anorectal manometry
143.0
50.5
53
*
JHB30
NOMESCO Finland
Rubber band ligature of haemorrhoids or prolapse of mucosa
10.8
49.6
99
105
K59.0
ICD-10 Finland
Constipation
15.1
48.3
82
61
JGC30
NOMESCO Finland
Excision and suture of rectal mucosa with imbrication of muscular layer
+∞
47.4
45
*
K56.5
ICD-10 Finland
Intestinal adhesions [bands] with obstruction
+∞
46.4
44
*
A06AD11
ATC
lactulose; oral
5.1
45.5
159
378
R19.5
ICD-10 Finland
Other faecal abnormalities
30.3
41.9
56
20
N81.1
ICD-10 Finland
Cystocele
5.6
41.8
133
282
LEF03
NOMESCO Finland
Posterior colporrpahy with sutures for primary rectocele
8.5
41.6
95
127
Z09.0
ICD-10 Finland
Follow-up examination after surgery for other conditions
5.3
41.3
137
304
UJF45
NOMESCO Finland
Flexible sigmoidoscopy with biopsy
7.8
41.0
99
144
TPH04
NOMESCO Finland
Cathetrisation of vein
3.7
40.1
212
737
JFB00
NOMESCO Finland
Partial resection of small intestine
35.0
38.1
49
15
WX704
NOMESCO Finland
Intubation
5.8
38.0
115
228
UJG02
NOMESCO Finland
Proctoscopy
20.2
37.2
56
30
ZXC96
NOMESCO Finland
Robot assisted procedure
11.8
36.7
69
64
LX1AE
NOMESCO Finland
Gynecological ultrasound examination as part of clinical examination
4.3
35.1
146
406
K59.00
ICD-10 Finland
Constipation caused by slow bowel passage (SCT)
52.8
33.8
40
8
K62.2
ICD-10 Finland
Anal prolapse
342.2
33.2
33
*
N39.4
ICD-10 Finland
Other specified urinary incontinence
4.7
32.5
121
300
Z01.8
ICD-10 Finland
Other specified special examinations
3.1
31.0
202
798
Z51.4
ICD-10 Finland
Preparatory care for subsequent treatment, not elsewhere classified
54.0
30.6
36
7
JG1JG
NOMESCO Finland
MRI of rectal function (MR defecography)
315.1
30.0
30
*
WX725
NOMESCO Finland
Noninvasive ventilation
6.7
29.7
79
131
K62.5
ICD-10 Finland
Haemorrhage of anus and rectum
12.9
29.7
53
44
JGC96
NOMESCO Finland
Other reconstructive operation on rectum
303.7
29.0
29
*
ZY020
NOMESCO Finland
Telephone, letter or other consultation without direct patient contact
5.2
27.7
91
196
N02BE01
ATC
paracetamol; systemic, rectal
3.5
27.3
639
5179
5600A
ICD-9 Finland
Intestinal obstruction without mention of hernia, Intussusception[INVAGINATIO INTESTINI TENUIS]
+∞
27.3
26
*
XKX00
NOMESCO Finland
Pelvic floor electromyography
64.7
27.2
31
5
B01AB05
ATC
enoxaparin; parenteral
2.6
26.7
264
1331
TPH07
NOMESCO Finland
Cathetrisation of artery
4.1
25.9
109
301
JAH00
NOMESCO Finland
Laparotomy
14.2
25.3
43
32
K58.9
ICD-10 Finland
Irritable bowel syndrome without diarrhoea
16.9
25.2
40
25
P01AB01
ATC
metronidazole; oral, rectal
2.4
24.9
317
1808
K59.4
ICD-10 Finland
Anal spasm
93.5
24.8
27
*
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
2.6
24.5
220
1043
K59.9
ICD-10 Finland
Functional intestinal disorder, unspecified
26.5
24.2
33
13
N03AX12
ATC
gabapentin; oral
3.1
23.7
148
556
N06AX21
ATC
duloxetine; oral
3.6
23.3
115
363
A06AC51
ATC
ispaghula, combinations; systemic
6.2
23.3
64
111
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
2.8
23.2
176
750
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
3.1
22.7
142
532
I84.2
ICD-10 Finland
Internal hemorrhoids without complication
4.8
22.5
78
178
JN3AD
NOMESCO Finland
Abdominal CT examination
5.5
22.2
68
135
N39.3
ICD-10 Finland
Stress incontinence
3.6
22.1
108
338
ZXE20
NOMESCO Finland
More than three and less than five hours
3.2
22.0
126
444
XKC03
NOMESCO Finland
Water cystometry
6.3
22.0
60
103
K58.0
ICD-10 Finland
Irritable bowel syndrome with diarrhoea
8.8
21.7
47
57
K56.7
ICD-10 Finland
Ileus, unspecified
118.7
21.7
23
*
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
4.0
21.6
93
261
SPAT1131
SPAT
Colonoscopy
6.8
21.6
55
86
N03AX16
ATC
pregabalin; oral
2.5
21.4
200
958
SPAT1262
SPAT
Handing over of treatment supplies
2.8
21.0
154
639
A02BC02
ATC
pantoprazole; systemic
2.2
21.0
468
3352
K59.1
ICD-10 Finland
Functional diarrhoea
6.8
20.8
53
83
WX408
NOMESCO Finland
General anesthesy, balanced
2.4
20.5
211
1059
S18
ICPC
Laceration/cut
2.1
20.1
320
1968
C05AA08
ATC
fluocortolone; rectal, topical
3.1
20.1
122
448
Z71.8
ICD-10 Finland
Other specified counselling
2.4
19.9
202
1004
JN3BD
NOMESCO Finland
Extensive abdominal CT
3.8
19.8
88
254
-1
NOMESCO Finland
NA
2.2
19.7
266
1515
JN3AA
NOMESCO Finland
Abdominal X-ray examination without contrast
6.9
19.5
49
75
XKD00
NOMESCO Finland
Uroflowmetry
3.4
19.3
102
338
N81.2
ICD-10 Finland
Incomplete uterovaginal prolapse
4.2
19.2
76
197
SHB00
NOMESCO Finland
Prepation and fitting of bite rail to mouth
3.3
19.0
102
342
J01MA02
ATC
ciprofloxacin; systemic
2.1
19.0
283
1679
N06AA09
ATC
amitriptyline; systemic
3.3
18.7
103
350
D17
ICPC
Incontinence of bowel
25.8
18.3
25
10
SPAT1263
SPAT
Sampling
2.1
18.3
316
1984
A02BC03
ATC
lansoprazole; oral
2.2
18.2
237
1319
UKC02
NOMESCO Finland
Cystoscopy
3.0
18.1
116
440
K60.1
ICD-10 Finland
Chronic anal fissure
54.0
18.0
21
*
N02AX02
ATC
tramadol; systemic, rectal
2.1
17.8
301
1868
K43.9
ICD-10 Finland
Other and unspecified ventral hernia without obstruction or gangrene
5.6
17.7
52
98
JF1AB
NOMESCO Finland
Passage examination of small bowell with X-ray
43.1
17.4
21
5
WX302
NOMESCO Finland
Thoracal epidural anesthesy
4.6
17.3
62
146
A02BC05
ATC
esomeprazole; systemic
2.0
17.2
302
1894
WX702
NOMESCO Finland
Supraglottic ventilation device
4.3
17.2
65
162
G03CA03
ATC
estradiol; nasal, systemic, rectal, transdermal, vaginal
2.0
17.1
401
2816
SPAT1301
SPAT
No procedures
2.1
17.1
249
1447
Y83
ICD-10 Finland
Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
3.8
17.1
75
214
Z3231
NOMESCO Finland
Registered nurse
2.2
16.8
207
1114
EB1AA
NOMESCO Finland
Tooth X-ray examination
2.0
16.8
401
2830
J01DB01
ATC
cefalexin; oral
2.2
16.7
572
4651
JGB96
NOMESCO Finland
Other proctectomy or excision of rectum
+∞
16.7
16
*
K62.8
ICD-10 Finland
Other specified diseases of anus and rectum
92.2
16.6
18
*
R51.80
ICD-10 Finland
Headache
2.7
16.1
124
524
WX720
NOMESCO Finland
Own respiration
4.8
16.0
54
120
SDA02
NOMESCO Finland
Parodonthologic therapy
2.0
15.7
252
1511
A07EC02
ATC
mesalazine; oral, rectal
4.9
15.7
52
113
45599
ICD-8 Finland
Haemorrhoids
+∞
15.7
15
*
K59.8
ICD-10 Finland
Other specified functional intestinal disorders
163.4
15.5
16
*
JHB00
NOMESCO Finland
Hemorrhoidectomy
7.3
15.5
37
53
M01AH05
ATC
etoricoxib; oral
1.9
15.4
431
3176
H02AB06
ATC
prednisolone; systemic
1.9
15.3
329
2201
JAH01
NOMESCO Finland
Laparoscopy
4.4
15.2
56
136
D04
ICPC
Rectal/anal pain
20.6
15.2
22
11
LEF51
NOMESCO Finland
Laparoscopic colpopexy after previous hysterectomy
16.9
14.8
23
14
K60.2
ICD-10 Finland
Anal fissure, unspecified
25.6
14.7
20
8
K56.0
ICD-10 Finland
Paralytic ileus
+∞
14.6
14
*
6453
FHL
Radical surgery of hemorrhoids
+∞
14.6
14
*
N02AJ06
ATC
codeine and paracetamol; systemic
2.0
14.5
262
1636
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
2.5
14.5
125
562
I84.9
ICD-10 Finland
Unspecified hemorrhoids without complication
4.8
14.4
48
105
J01EA01
ATC
trimethoprim; systemic
2.1
14.3
211
1212
M03BX02
ATC
tizanidine; oral
1.9
14.3
446
3371
N05CF01
ATC
zopiclone; oral
2.0
14.3
233
1396
G04BD12
ATC
mirabegron; oral
2.9
14.2
91
344
D06
ICPC
Abdominal pain localized other
3.4
14.2
70
220
WX402
NOMESCO Finland
General anaesthesia
2.3
14.1
139
669
N06AX11
ATC
mirtazapine; oral
2.0
13.7
232
1406
Z50.9
ICD-10 Finland
Care involving use of rehabilitation procedure, unspecified
4.6
13.6
47
107
LCC11
NOMESCO Finland
Laparoscopic subtotal hysterectomy
+∞
13.6
13
*
K56.2
ICD-10 Finland
Volvulus
+∞
13.6
13
*
ABD32
NOMESCO Finland
Implantation of temporary spinal stimulation device
34.8
13.5
17
5
HMAK
NOMESCO Finland
NA
2.5
13.5
112
492
LEF00
NOMESCO Finland
Anterior colporraphy with sutures for primary cystocele
4.0
13.4
54
143
ABD30
NOMESCO Finland
Implantation of spinal stimulation device
21.6
13.4
19
9
D01
ICPC
Abdominal pain/cramps general
2.9
13.3
85
319
D12
ICPC
Constipation
6.3
13.3
35
58
K50.0
ICD-10 Finland
Crohn disease of small intestine
17.1
13.0
20
12
M54.5
ICD-10 Finland
Low back pain
1.9
13.0
234
1442
M79.6
ICD-10 Finland
Pain in limb
1.9
13.0
264
1703
UJF30
NOMESCO Finland
Ileoscopy through colon
3.7
13.0
57
163
SPAT1153
SPAT
Removal of sutures
1.9
13.0
235
1455
M51.1
ICD-10 Finland
Lumbar and other intervertebral disc disorders with radiculopathy
2.4
12.9
113
510
M51.3
ICD-10 Finland
Other specified intervertebral disc degeneration
3.2
12.8
69
232
SPAT1253
SPAT
Initiation, adjustment, discontinuation or repetition of medication
1.9
12.8
225
1378
Z00.0
ICD-10 Finland
General medical examination
2.2
12.7
145
742
SAA03
NOMESCO Finland
Extended examination of mouth
1.8
12.5
276
1822
SAA01
NOMESCO Finland
Simple examination of mouth
1.8
12.5
488
3882
SPAT1097
SPAT
Recording of ECG
2.4
12.3
112
515
R03AC02
ATC
salbutamol; inhalant
1.8
12.3
381
2806
JHB96
NOMESCO Finland
Other procedure for haemorrhoids or prolapse of mucosa
38.2
12.2
15
*
M01AC06
ATC
meloxicam; systemic, rectal
1.8
12.2
271
1794
K50.8
ICD-10 Finland
Other Crohn disease
12.7
12.2
21
17
Z71.3
ICD-10 Finland
Dietary counselling and surveillance
4.0
12.1
48
126
R10.1
ICD-10 Finland
Pain localized to upper abdomen
2.3
12.0
117
556
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.8
12.0
316
2206
D18
ICPC
Change in faeces/bowel movements
6.6
12.0
30
47
SFA10
NOMESCO Finland
Fillning on one surface of tooth
1.8
11.7
367
2697
AEA24
NOMESCO Finland
Removal of spinal stimulation elecrode
121.9
11.5
12
*
G04BD08
ATC
solifenacin; oral
3.1
11.3
63
215
A02BC01
ATC
omeprazole; systemic
1.9
11.3
189
1128
N99.3
ICD-10 Finland
Prolapse of vaginal vault after hysterectomy
5.4
11.2
33
64
SPAT1240
SPAT
Therapeutic discussion
2.6
11.2
86
361
WYA05
NOMESCO Finland
Emergency visit or other similar visit involving procedures
1.7
11.1
338
2447
R10.2
ICD-10 Finland
Pelvic and perineal pain
6.4
11.0
28
45
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
2.5
10.8
87
374
L03
ICPC
Low back symptom/complaint
1.9
10.8
173
1013
SPAT1216
SPAT
Assessment of functional ability
2.3
10.8
111
537
M54.4
ICD-10 Finland
Lumbago with sciatica
2.2
10.8
118
591
SPAT1310
SPAT
Counselling related to known health issue
1.8
10.8
231
1495
J02AC01
ATC
fluconazole; systemic
1.7
10.8
313
2227
A07EA02
ATC
hydrocortisone; rectal
7.7
10.7
24
32
S15
ICPC
Foreign body in skin
3.2
10.7
55
179
R01AD01
ATC
beclometasone; nasal
2.1
10.7
127
657
SAA02
NOMESCO Finland
Basic examination of mouth
1.7
10.7
440
3469
F32.10
ICD-10 Finland
Moderate depressive episode without somatic syndrome
2.8
10.6
69
261
SPAT1028
SPAT
Ultrasound examination of paranasal sinuses
3.2
10.6
55
180
K30
ICD-10 Finland
Functional dyspepsia
2.6
10.6
80
332
KMAK
NOMESCO Finland
NA
1.7
10.6
360
2682
I84.5
ICD-10 Finland
External hemorrhoids without complication
5.5
10.5
30
56
JFK10
NOMESCO Finland
Freeing of adhesions in intestinal obstruction
+∞
10.4
10
*
WX400
NOMESCO Finland
Inhalation anesthesy
3.5
10.4
47
139
LX1XE
NOMESCO Finland
Other gynecological ultrasound examination
4.2
10.4
39
98
WZB00
NOMESCO Finland
Telephone receipt or other advice
1.8
10.3
200
1247
N02CC01
ATC
sumatriptan; nasal, systemic, rectal
2.3
10.3
104
501
SHA02
NOMESCO Finland
Correction of physiology of bite - basic therapy visit
3.1
10.3
56
190
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.7
10.3
272
1877
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
2.5
10.2
80
337
208
Kela drug reimbursment
Ulcerative colitis and Crohn's disease
4.3
10.2
37
90
LC2BE
NOMESCO Finland
Transvaginal ultrasound examination of uterus, parametria and lower abdomen
1.8
10.0
211
1353
A03FA02
ATC
cisapride; oral, rectal
2.8
10.0
63
235
K57.9
ICD-10 Finland
Diverticular disease of intestine, part unspecified, without perforation or abscess
14.8
10.0
16
11
601
Kela drug reimbursment
Severe malabsorption of nutrients, mainly fats
14.8
10.0
16
11
N05CF02
ATC
zolpidem; oral
2.0
10.0
136
746
R03BA01
ATC
beclometasone; inhalant
2.1
9.9
114
582
C10AC01
ATC
colestyramine; oral
6.1
9.9
26
44
JFB30
NOMESCO Finland
Right hemicolectomy
12.4
9.9
17
14
D93
ICPC
Irritable bowel syndrome
10.8
9.8
18
17
JAP00
NOMESCO Finland
Freeing of adhesions in the peritoneal cavity
9.7
9.8
19
20
U01
ICPC
Dysuria/painful urination
2.7
9.8
69
276
J01CA08
ATC
pivmecillinam; oral
1.7
9.8
321
2346
A44
ICPC
General and Unspecified, Preventive immunization/medic
2.7
9.7
65
252
F33.10
ICD-10 Finland
Recurrent depression, moderate episode without somatic syndrome
3.4
9.7
47
147
K57.2
ICD-10 Finland
Diverticular disease of large intestine with perforation and abscess
55.7
9.7
11
*
K07.60
ICD-10 Finland
Snapping jaw
3.4
9.6
46
143
A07EA06
ATC
budesonide; oral, local oral
4.9
9.6
30
63
M79.0
ICD-10 Finland
Rheumatism, unspecified
3.9
9.5
38
101
R35
ICD-10 Finland
Polyuria
3.3
9.5
46
144
SPAT1130
SPAT
Esophagoscopy, gastroscopy and duodenoscopy
4.1
9.5
36
92
U07
ICPC
Urine symptom/complaint other
3.1
9.4
50
167
R53
ICD-10 Finland
Malaise and fatigue
2.0
9.4
137
769
JF1CG
NOMESCO Finland
Extensive MRI of small bowel
101.3
9.4
10
*
C07AB07
ATC
bisoprolol; oral
1.7
9.4
288
2057
JHW96
NOMESCO Finland
Other operation on anus or perianal tissue
+∞
9.4
9
*
T81.0
ICD-10 Finland
Haemorrhage and haematoma complicating a procedure, not elsewhere classified
3.2
9.3
49
163
M54.2
ICD-10 Finland
Cervicalgia
2.8
9.3
58
215
K50.9
ICD-10 Finland
Crohn disease, unspecified
9.7
9.3
18
19
R21
ICPC
Throat symptom/complaint
2.0
9.3
136
767
N05AH04
ATC
quetiapine; oral
2.1
9.2
113
591
R03DC03
ATC
montelukast; oral
2.0
9.2
119
638
D37.2
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Small intestine
13.9
9.2
15
11
RF420
NOMESCO Finland
NA
6.8
9.2
22
33
JAD30
NOMESCO Finland
Repair of incisional hernia using prosthetic material
7.9
9.2
20
26
XKD03
NOMESCO Finland
Urethral pressure profilometry
4.3
9.2
33
80
R11
ICD-10 Finland
Nausea and vomiting
2.8
9.2
57
211
J01FA10
ATC
azithromycin; systemic
1.6
9.1
405
3191
R05
ICPC
Cough
1.8
9.1
164
996
M79.7
ICD-10 Finland
Fibromyalgia
3.8
9.1
37
101
A06AX04
ATC
linaclotide; oral
37.2
9.0
11
*
N30.0
ICD-10 Finland
Acute cystitis
2.1
9.0
104
533
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
1.8
9.0
199
1286
A01
ICPC
Pain general/multiple sites
2.7
9.0
63
249
Z01.5
ICD-10 Finland
Diagnostic skin and sensitization tests
2.4
9.0
78
348
RF410
NOMESCO Finland
NA
7.6
9.0
20
27
D12.6
ICD-10 Finland
Benign neoplasm: Colon, unspecified
4.2
9.0
33
82
K60.0
ICD-10 Finland
Acute anal fissure
24.3
8.9
12
5
TJD00
NOMESCO Finland
Insertion of nasogastric or naso-gastroduodenal tube
12.7
8.9
15
12
N06AB06
ATC
sertraline; oral
2.3
8.9
82
377
7890A
ICD-9 Finland
Other symptoms involving abdomen and pelvis, Abdominal pain
3.1
8.8
47
158
Z01.0
ICD-10 Finland
Examination of eyes and vision
2.0
8.8
118
642
SPAT1256
SPAT
Intramuscular and subcutaneous injection
1.6
8.8
283
2039
WZC30
NOMESCO Finland
Teaching
2.1
8.7
100
510
G56.0
ICD-10 Finland
Carpal tunnel syndrome
2.1
8.7
101
517
R01AD58
ATC
fluticasone, combinations; inhalant, nasal
1.8
8.6
154
930
K50.1
ICD-10 Finland
Crohn disease of large intestine
11.8
8.6
15
13
M48.0
ICD-10 Finland
Spinal stenosis
2.3
8.6
83
391
K62.6
ICD-10 Finland
Ulcer of anus and rectum
16.5
8.6
13
8
WX290
NOMESCO Finland
Other blockade of nerve
1.6
8.5
284
2066
RF210
NOMESCO Finland
NA
4.0
8.4
32
82
X15
ICPC
Vaginal symptom/complaint other
3.9
8.4
33
87
JHD10
NOMESCO Finland
Myotomy of anal sphincter
91.1
8.4
9
*
R19.4
ICD-10 Finland
Change in bowel habit
5.1
8.4
25
50
SPAT1044
SPAT
Tympanometry
5.1
8.4
25
50
U05
ICPC
Urination problems other
3.7
8.4
35
98
6402
FHL
Small bowel resection
+∞
8.3
8
*
K91.4
ICD-10 Finland
Colostomy and enterostomy malfunction
+∞
8.3
8
*
SHA03
NOMESCO Finland
Correction of physiology of bite - demanding therapy visit
3.9
8.3
33
88
M75.1
ICD-10 Finland
Rotator cuff syndrome
1.8
8.3
158
973
SPAT1252
SPAT
Overall medication plan or its review
2.7
8.3
56
218
N02AA05
ATC
oxycodone; systemic
2.1
8.3
92
460
N05BA04
ATC
oxazepam; oral
1.8
8.3
171
1078
N06AX26
ATC
vortioxetine; oral
3.1
8.3
45
154
R02
ICPC
Shortness of breath/dyspnoea
2.2
8.3
84
407
G44.2
ICD-10 Finland
Tension-type headache
2.1
8.1
93
472
D07AB02
ATC
hydrocortisone butyrate; topical
1.7
8.1
190
1246
SHA01
NOMESCO Finland
Correction of physiology of bite - simple therapy visit
2.2
8.1
80
381
J31.0
ICD-10 Finland
Chronic rhinitis
2.5
8.1
61
253
LEF40
NOMESCO Finland
Vaginal repair of enterocele
10.2
8.1
15
15
JFB20
NOMESCO Finland
Ileocaecal resection
22.3
8.0
11
5
L04AX01
ATC
azathioprine; systemic
3.5
8.0
36
107
H01
ICPC
Ear pain/earache
2.2
8.0
82
398
A01AB09
ATC
miconazole; local oral
2.4
8.0
69
307
Z87.1
ICD-10 Finland
Personal history of diseases of the digestive system
1.6
8.0
297
2207
A07DA03
ATC
loperamide; oral
3.9
7.9
31
82
L08
ICPC
Shoulder symptom/complaint
1.9
7.9
132
776
N06AB03
ATC
fluoxetine; oral
2.1
7.9
88
444
F45.8
ICD-10 Finland
Other somatoform disorders
2.6
7.9
55
220
SPAT1324
SPAT
Screening procedure
1.8
7.9
143
866
R03BA08
ATC
ciclesonide; inhalant
2.4
7.8
63
272
F33.11
ICD-10 Finland
Recurrent depression, moderate episode of somatic syndrome
5.4
7.7
22
42
J45.9
ICD-10 Finland
Asthma, unspecified
1.9
7.7
122
702
326
Kela drug reimbursment
Adalimumab, golimumab, infliximab and ustekinumab (intestinal diseases)
15.2
7.7
12
8
N06AX16
ATC
venlafaxine; oral
2.0
7.7
96
507
XQ848
NOMESCO Finland
Dermatological photography
5.0
7.6
23
47
JF1BD
NOMESCO Finland
Very extensive small bowel CT
18.6
7.6
11
6
TJG20
NOMESCO Finland
Transanal irrigation
25.3
7.6
10
*
T81.8
ICD-10 Finland
Other complications of procedures, not elsewhere classified
5.5
7.6
21
39
ZXD05
NOMESCO Finland
Urgent procedure
1.7
7.5
186
1236
Z01.2
ICD-10 Finland
Dental examination
1.6
7.5
273
2010
R10.0
ICD-10 Finland
Acute abdomen
5.1
7.5
22
44
M01AH01
ATC
celecoxib; oral (coxibs)
1.9
7.5
125
735
A02BA02
ATC
ranitidine; systemic
1.8
7.4
130
777
K62.9
ICD-10 Finland
Disease of anus and rectum, unspecified
80.9
7.4
8
*
J01AA07
ATC
tetracycline; systemic
1.9
7.4
106
591
D29
ICPC
Digestive symptom/complaint other
5.7
7.4
20
36
HAMTE
NOMESCO Finland
NA
13.5
7.4
12
9
Z01.1
ICD-10 Finland
Examination of ears and hearing
2.1
7.4
88
456
ZX120
NOMESCO Finland
Intravenous
2.3
7.4
68
315
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
1.9
7.3
116
670
U04
ICPC
Incontinence urine
3.1
7.3
38
127
K60.3
ICD-10 Finland
Anal fistula
+∞
7.3
7
*
K63.1
ICD-10 Finland
Perforation of intestine (nontraumatic)
+∞
7.3
7
*
5621B
ICD-9 Finland
Diverticula of intestine, Colon[DIVERTICULITIS COLI SINE HAEMORRHAGIA]
+∞
7.3
7
*
JHB40
NOMESCO Finland
Resection and stapled suture of anal mucosa
+∞
7.3
7
*
M17.1
ICD-10 Finland
Other primary gonarthrosis
1.8
7.3
140
862
I84.1
ICD-10 Finland
Internal hemorrhoids with other complications
5.2
7.3
21
41
R07.0
ICD-10 Finland
Pain in throat
2.9
7.3
43
156
M01AE03
ATC
ketoprofen; systemic, rectal
1.6
7.3
250
1810
D12.9
ICD-10 Finland
Benign neoplasm: Anus and anal canal
15.9
7.2
11
7
XLD10
NOMESCO Finland
Gynaecological examination
15.9
7.2
11
7
D11
ICPC
Diarrhoea
2.2
7.2
72
345
F43.1
ICD-10 Finland
Post-traumatic stress disorder
4.5
7.2
24
55
DMB20
NOMESCO Finland
Functional endoscopic opening of maxillary antrum
2.9
7.2
42
151
K57.1
ICD-10 Finland
Diverticular disease of small intestine without perforation or abscess
30.3
7.2
9
*
WX004
NOMESCO Finland
Patient-controlled sedation
20.2
7.1
10
5
J01EE02
ATC
sulfadiazine and trimethoprim; systemic
1.7
7.1
177
1177
R07.4
ICD-10 Finland
Chest pain, unspecified
1.7
7.1
161
1041
K21.0
ICD-10 Finland
Gastro-oesophageal reflux disease with oesophagitis
2.3
7.1
64
293
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
2.4
7.1
61
272
G43.1
ICD-10 Finland
Migraine with aura [classical migraine]
2.5
7.1
53
221
D07CA01
ATC
hydrocortisone and antibiotics; topical
2.0
7.1
92
494
F33.00
ICD-10 Finland
Recurrent depression, mild episode without somatic syndrome
4.8
7.1
22
47
R09
ICPC
Sinus symptom/complaint
2.3
7.1
63
285
N06AB10
ATC
escitalopram; oral
1.8
7.0
133
816
J01DA01
ATC
[U] cefalexin; systemic
1.5
7.0
414
3398
KC1EE
NOMESCO Finland
Ultrasound measurement of residual urine
2.3
6.9
61
277
R42
ICD-10 Finland
Dizziness and giddiness
1.8
6.9
137
851
U02
ICPC
Urinary frequency/urgency
1.9
6.9
100
558
H13
ICPC
Plugged feeling ear
1.8
6.9
117
690
R01AD12
ATC
fluticasone furoate; nasal
1.6
6.9
195
1339
SPAT1312
SPAT
General health counselling
1.6
6.9
212
1490
N05BA01
ATC
diazepam; systemic, rectal
2.0
6.8
92
500
AN2
HP
Balloon angioplasty, including several vessels
4.6
6.8
22
49
JFB47
NOMESCO Finland
Laparoscopic resection of sigmoid colon
11.1
6.8
12
11
N06AB04
ATC
citalopram; systemic
1.7
6.8
142
897
D02
ICPC
Abdominal pain epigastric
2.8
6.8
43
161
N06CA01
ATC
amitriptyline and psycholeptics; systemic
2.1
6.8
78
399
K52.9
ICD-10 Finland
Noninfective gastroenteritis and colitis, unspecified
4.4
6.8
23
54
JAD10
NOMESCO Finland
Repair of incisional hernia
16.9
6.8
10
6
SCA01
NOMESCO Finland
Simple analysis and advice of nutrition with regard to dentistry
1.6
6.8
183
1243
WX110
NOMESCO Finland
Local anesthesy
1.5
6.7
449
3769
XQ800
NOMESCO Finland
Prick test
2.4
6.7
54
235
107
Kela drug reimbursment
Pernicious anaemia
6.5
6.7
16
25
M25.5
ICD-10 Finland
Pain in joint
1.6
6.7
189
1300
A04
ICPC
Weakness/tiredness general
2.0
6.6
81
425
JFA15
NOMESCO Finland
Endoscopic polypectomy in colon
3.8
6.6
26
70
R96
ICPC
Asthma
2.2
6.6
65
309
SAD01
NOMESCO Finland
Assessment of need for oral health care, standard
1.9
6.6
90
493
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
2.4
6.6
52
223
EB1SA
NOMESCO Finland
Dental X-ray, bite-wing X-ray on one side of the mouth
1.5
6.6
313
2433
TJF80
NOMESCO Finland
Ostomy education
10.1
6.5
12
12
N06AX12
ATC
bupropion; oral
2.7
6.5
43
168
E000006
ATC
NA
2.3
6.5
58
266
R06AX27
ATC
desloratadine; oral
1.6
6.5
183
1253
N39.0
ICD-10 Finland
Urinary tract infection, site not specified
2.0
6.5
89
486
M03BC01
ATC
orphenadrine (citrate); systemic
1.7
6.4
156
1024
N06AB05
ATC
paroxetine; oral
2.5
6.4
46
188
JF1DG
NOMESCO Finland
Small bowel very extensive MRI with with high intensity magnet
70.4
6.4
7
*
SPAT1260
SPAT
Consultation of another employee
1.8
6.4
120
732
M01AE02
ATC
naproxen; oral, rectal
1.5
6.4
368
2975
ITSEH
NOMESCO Finland
NA
14.5
6.4
10
7
UJF02
NOMESCO Finland
Peroral enteroscopy
14.5
6.4
10
7
M03BA52
ATC
carisoprodol, combinations excl. psycholeptics; oral
3.0
6.4
35
122
L15
ICPC
Knee symptom/complaint
1.7
6.4
141
904
K05.10
ICD-10 Finland
Gingivitis (chronic) NOS
2.0
6.4
81
432
ZX136
NOMESCO Finland
Intravesicalis
8.2
6.3
13
16
7840A
ICD-9 Finland
Symptoms involving head and neck, Headache
8.2
6.3
13
16
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.5
6.3
324
2551
UDH02
NOMESCO Finland
Rhinopharyngoscopy
2.6
6.3
45
183
L01
ICPC
Neck symptom/complaint
1.9
6.3
90
500
121
Kela drug reimbursment
Severe hypofunction of sexual glands
4.6
6.3
20
44
J01AA02
ATC
doxycycline; systemic
1.6
6.3
519
4527
L17
ICPC
Foot/toe symptom/complaint
1.6
6.3
162
1080
LCA06
NOMESCO Finland
Biopsy of endometrium
1.9
6.3
100
575
5608A
ICD-9 Finland
Intestinal obstruction without mention of hernia, Other specified intestinal obstruction[OBSTRUCTIO INTESTINALIS ,ADHESIONES INTRAABDOMINALE]
+∞
6.3
6
*
5600B
ICD-9 Finland
Intestinal obstruction without mention of hernia, Intussusception[INVAGINATIO COLI]
+∞
6.3
6
*
5609X
ICD-9 Finland
Intestinal obstruction without mention of hernia, Unspecified intestinal obstruction
+∞
6.3
6
*
JGC00
NOMESCO Finland
Rectopexy
+∞
6.3
6
*
P01
ICPC
Feeling anxious/nervous/tense
2.2
6.3
65
317
LEG13
NOMESCO Finland
Vaginal transobturatorial urethropexy
7.1
6.2
14
20
K62.0
ICD-10 Finland
Anal polyp
26.9
6.2
8
*
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
2.0
6.2
74
384
WX306
NOMESCO Finland
Lumbar epidural anesthesy
2.4
6.2
48
205
TKC22
NOMESCO Finland
Catheterisation instruction
5.1
6.2
18
36
D16
ICPC
Rectal bleeding
5.1
6.2
18
36
M54.3
ICD-10 Finland
Sciatica
2.5
6.2
45
186
M01AE01
ATC
ibuprofen; systemic, rectal
1.7
6.2
610
5559
B03BA03
ATC
hydroxocobalamin; parenteral
2.9
6.2
36
130
RF120
NOMESCO Finland
NA
5.8
6.2
16
28
SDE02
NOMESCO Finland
Periodontal treatment by dental hygienist
1.6
6.2
166
1121
M53.1
ICD-10 Finland
Cervicobrachial syndrome
2.0
6.1
75
393
R01AD09
ATC
mometasone; nasal
1.5
6.1
297
2309
SDA01
NOMESCO Finland
Simple parodonthologic therapy
1.6
6.1
170
1160
SBB10
NOMESCO Finland
Teeth copy
2.5
6.1
46
192
K92.1
ICD-10 Finland
Melaena
3.2
6.1
29
92
F32.2
ICD-10 Finland
Severe depressive episode without psychotic symptoms
2.5
6.1
46
193
R2130
NOMESCO Finland
Counselling and guidance which enhance independent living
2.3
6.1
54
245
M19.0
ICD-10 Finland
Primary arthrosis of other joints
2.1
6.0
66
330
M54.6
ICD-10 Finland
Pain in thoracic spine
2.5
6.0
46
194
R1250
NOMESCO Finland
Evaluation of functional capability
3.9
6.0
23
61
J01CA04
ATC
amoxicillin; systemic
1.6
6.0
538
4754
Mortality – FinRegistry
↥Association
Association between endpoint K11_INTUSS and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| K11_INTUSS | 1.281 [1.07, 1.53] | 0.006 |
| Birth year | 0.996 [0.99, 1.0] | 0.363 |
During the follow-up period (1.1.1998 — 31.12.2019), 334 out of 2809 females with K11_INTUSS died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| K11_INTUSS | 2.788 [1.96, 3.96] | < 0.001 |
| Birth year | 0.986 [0.98, 1.0] | 0.005 |
During the follow-up period (1.1.1998 — 31.12.2019), 265 out of 1029 males with K11_INTUSS died.
Mortality risk
Mortality risk for people of age
years, who have K11_INTUSS.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.137% | 0.581% |
| 5 | 0.777% | 3.046% |
| 10 | 1.956% | 7.562% |
| 15 | 3.914% | 14.165% |
| 20 | 7.014% | 23.381% |
Relationships between endpoints
↥Index endpoint: K11_INTUSS – Intussusception
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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