Risteys · I9_ARTEMBTHRLOW

Endpoint definition steps	FinnGen
Phenotype data	520210
1. Apply sex-specific rule None	520210
2. Check conditions None	520210
3. Check pre-conditions, main-only, mode, registry filters Registry filters: Hospital discharge: ICD-10 — I74.3 Hospital discharge: ICD-9 — 4442A Cause of death: ICD-10 — I74.3 Cause of death: ICD-9 — 4442A 2 out of 7 registries used, show all original rules.	1326
4. Check minimum number of events None	1326
5. Include endpoints None	1326
6. Filter based on genotype QC (FinnGen only)	1326

	All	Female	Male
Number of individuals
Whole population	15872	7887	7734
Only index persons	9951	4973	4978
Unadjusted period prevalence (%)
Whole population	0.22	0.23	0.22
Only index persons	0.19	0.18	0.19
Median age at first event (years)
Whole population	75.44	80.10	70.77
Only index persons	74.25	79.43	69.07

	All	Female	Male
Number of individuals	1326	510	816
Unadjusted period prevalence (%)	0.29	0.17	0.36
Median age at first event (years)	70.09	70.64	69.75

CodeWAS (R11)

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log₁₀(p-value) ≥ 6.

Matched cohort

Matched cases
1204: Matched controls
12044

Code

Vocabulary

Description

Odds Ratio

-log₁₀(p)

N matched cases

N matched controls

I70.2

ICD-10 Finland

Atherosclerosis of arteries of extremities

386.7

323.0

766

I74.3

ICD-10 Finland

Embolism and thrombosis of arteries of lower extremities

14477.3

323.0

1114

XPX99

NOMESCO Finland

Other diagnostic examination of periferal vessel

25.9

266.5

385

214

PD4AC

NOMESCO Finland

Arterigography of lower extremity with X-ray

318.5

166.2

165

PD4BC

NOMESCO Finland

Extensive arterigography of lower extremity with X-ray

833.5

152.8

147

PD4CG

NOMESCO Finland

Extensive MRI examination of abdominal aortta and vasculature of lower extremities with high intensity magnet

341.4

150.3

149

NFQ20

NOMESCO Finland

Amputation of femur

814.1

149.5

144

PEE23

NOMESCO Finland

Thrombectomy or embolectomy of femoral artery

1590.6

147.0

140

NGM10

NOMESCO Finland

Fasciotomy of of knee or lower leg

106.8

146.2

158

B01AA03

ATC

warfarin; systemic

5.1

143.8

648

2251

PEH57

NOMESCO Finland

Bypass from femoral artery to popliteal artery below knee

+∞

143.6

135

QDB10

NOMESCO Finland

Major dressing of wound of skin of lower limb

18.3

143.4

230

153

PEF23

NOMESCO Finland

Thrombendarterectomy of femoral artery

1517.1

141.6

135

ZXD05

NOMESCO Finland

Urgent procedure

4.8

136.3

646

2325

PFE26

NOMESCO Finland

Thrombectomy or embolectomy of popliteal artery

1366.4

128.6

123

PEH56

NOMESCO Finland

Bypass from femoral to popliteal artery above knee

+∞

128.5

121

PD4DE

NOMESCO Finland

Lower extremity artery ultrasound examination with Doppler method

96.5

125.1

137

PG1UT

NOMESCO Finland

Percutaneous aspiration throbectomy

440.0

122.0

120

I70.9

ICD-10 Finland

Generalized and unspecified atherosclerosis

268.5

120.2

121

PEE25

NOMESCO Finland

Thrombectomy or embolectomy of superficial femoral artery

1243.7

117.8

113

PE1AT

NOMESCO Finland

Femoral artery PTA

601.7

112.8

110

4442A

ICD-9 Finland

Arterial embolism and thrombosis, Of arteries of the extremities

+∞

104.7

PF1AT

NOMESCO Finland

Intravascular dilatation of arteries of knee, lower leg and ankle (PTA)

+∞

101.5

PD4BD

NOMESCO Finland

Extensive CT of lower extremity arteries

+∞

99.3

PD3YT

NOMESCO Finland

Pelvic artery PTA with stent

993.1

95.3

B01AC04

ATC

clopidogrel; oral

4.4

93.3

409

1247

PD4CC

NOMESCO Finland

Very extensive arterigography of lower extremity with X-ray

969.7

93.1

PG1ST

NOMESCO Finland

Endovascular arterial thrombolysis with radiological guidance not elsewhere classified

+∞

92.9

I71.4

ICD-10 Finland

Abdominal aortic aneurysm, without mention of rupture

150.4

92.5

4402A

ICD-9 Finland

Atherosclerosis, Of native arteries of the extremities

+∞

90.8

PE1YT

NOMESCO Finland

Femoral or popliteal artery PTA with stent

923.2

88.9

E11.5

ICD-10 Finland

Type 2 diabetes mellitus, with peripheral circulatory complications

100.7

85.3

NHQ40

NOMESCO Finland

Amputation of toe

+∞

84.4

QDB05

NOMESCO Finland

Revision of wound of skin of lower limb

19.4

81.4

126

I72.4

ICD-10 Finland

Aneurysm and dissection of artery of lower extremity

+∞

79.0

PD4ST

NOMESCO Finland

Endovascular thrombolysis of pelvic and lower extremity arteries

+∞

78.0

PH2AE

NOMESCO Finland

Ultrasound examination of lower leg veins

5.1

76.5

271

646

PFE99

NOMESCO Finland

Thrombectomy or embolectomy of artery of lower leg or foot

774.2

75.1

PG1DE

NOMESCO Finland

Other extensive ultrasound examination of artery

11.3

74.1

145

144

C03CA01

ATC

furosemide; systemic

3.0

70.8

655

3419

ZPB22

NOMESCO Finland

Autograft of vein

+∞

69.4

ZXE20

NOMESCO Finland

More than three and less than five hours

4.3

68.8

295

845

L97

ICD-10 Finland

Ulcer of lower limb, not elsewhere classified

11.4

65.1

126

122

GD1UA

NOMESCO Finland

Thorax X-ray examination outside radiological department

3.7

64.9

335

1126

PEN23

NOMESCO Finland

Plastic repair of femoral artery

340.9

64.1

B01AB05

ATC

enoxaparin; parenteral

3.0

61.9

498

2305

XPX00

NOMESCO Finland

Intraoperative angiography

628.5

61.3

XPX08

NOMESCO Finland

Intraoperative flow measurement

67.4

61.0

T81.4

ICD-10 Finland

Infection following a procedure, not elsewhere classified

4.7

59.7

223

550

I50.9

ICD-10 Finland

Heart failure, unspecified

3.2

56.6

377

1515

TPH07

NOMESCO Finland

Cathetrisation of artery

4.1

54.9

238

676

PEE24

NOMESCO Finland

Thrombectomy or embolectomy of deep femoral artery

+∞

52.5

ZZA00

NOMESCO Finland

Split skin graft

8.7

51.9

116

145

QDG20

NOMESCO Finland

Operation for chronic ulcer or fistula of skin of lower limb

40.3

51.8

WX408

NOMESCO Finland

General anesthesy, balanced

2.9

50.9

404

1799

NGQ20

NOMESCO Finland

Amputation of lower leg

+∞

50.4

ZPB40

NOMESCO Finland

Polytetrafluoroethylene

260.4

49.4

PE1BT

NOMESCO Finland

Femoral artery extensive PTA

496.9

48.7

I25.1

ICD-10 Finland

Atherosclerotic heart disease

2.6

48.7

467

2323

TPH15

NOMESCO Finland

Insertion of central venous catheter through external or internal jugular vein

5.6

47.8

149

297

S97

ICPC

Chronic ulcer skin

5.9

47.3

140

262

PD3AT

NOMESCO Finland

Pelvic artery PTA

+∞

47.2

5585

FHL

Embolectomy or thrombectomy

+∞

47.2

SPAT1148

SPAT

Treatment of chronic ulcer or burn

3.3

47.0

279

1013

I48

ICD-10 Finland

Atrial fibrillation and flutter

2.5

46.6

497

2606

PF1BT

NOMESCO Finland

Extensive PTA of arteries of knee, lower leg and ankle

+∞

45.1

PD4AD

NOMESCO Finland

CT of lower extremity arteries

453.6

44.5

PH2CD

NOMESCO Finland

Very extensive CT of inferior vena cava, pelvic veins and veins of lower extremity

159.2

44.1

TQW11

NOMESCO Finland

Vacuum treatment of wound

15.4

42.0

E11.7

ICD-10 Finland

Type 2 diabetes mellitus, with multiple complications

5.0

41.8

144

320

ZXE30

NOMESCO Finland

More than five and less than seven hours

5.8

41.5

123

230

WX892

NOMESCO Finland

Monitored bed care

4.2

41.2

169

448

I74.2

ICD-10 Finland

Embolism and thrombosis of arteries of upper extremities

+∞

40.9

Y83

ICD-10 Finland

Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure

4.4

39.1

154

392

A46

ICD-10 Finland

Erysipelas

3.0

38.8

261

1020

PEF25

NOMESCO Finland

Thrombendarterectomy of superficial femoral artery

+∞

38.7

PGH47

NOMESCO Finland

Bypass from femoral to contralateral femoral artery

+∞

38.7

C07AB07

ATC

bisoprolol; oral

2.2

37.6

697

4628

GD1QA

NOMESCO Finland

Supine thorax X-ray examination

2.7

37.3

319

1439

N02AX02

ATC

tramadol; systemic, rectal

2.2

37.3

574

3498

PWG00

NOMESCO Finland

Reoperation on peripheral vessels for thrombosis or embolism

378.4

37.2

PWE00

NOMESCO Finland

Reoperation for deep haemorrhage in surgery of peripheral vessels and lymphatic system

72.3

37.2

GD1PA

NOMESCO Finland

X-ray examination of the lungs in one projection

3.6

36.8

185

583

I80.3

ICD-10 Finland

Phlebitis and thrombophlebitis of lower extremities, unspecified

5.5

35.7

111

219

GD1AA

NOMESCO Finland

Thorax X-ray examination

2.2

35.2

592

3718

SPAT1144

SPAT

Treatment of reopened or infected surgical wound

4.3

35.2

139

354

I70.0

ICD-10 Finland

Atherosclerosis of aorta

357.0

35.1

K92

ICPC

Atherosclerosis/periph vascular dis

16.7

34.9

T81.0

ICD-10 Finland

Haemorrhage and haematoma complicating a procedure, not elsewhere classified

4.7

34.6

125

291

PEF24

NOMESCO Finland

Thrombendarterectomy of deep femoral artery

+∞

34.5

PFH63

NOMESCO Finland

Bypass from femoral or popliteal artery to distal posterior tibial artery

+∞

34.5

PEN24

NOMESCO Finland

Plastic repair of deep femoral artery

+∞

34.5

M79.6

ICD-10 Finland

Pain in limb

2.3

34.3

443

2461

I50.0

ICD-10 Finland

Congestive heart failure

3.2

34.2

197

687

N02AA05

ATC

oxycodone; systemic

2.7

34.1

273

1177

PEP25

NOMESCO Finland

Percutaneous plastic repair of superficial femoral artery

+∞

33.5

NHQ30

NOMESCO Finland

Amputation of foot, transmetatarsal

+∞

33.5

ZXE10

NOMESCO Finland

More than one and less than three hours

2.2

32.9

476

2771

T82.8

ICD-10 Finland

Other specified complications of cardiac and vascular prosthetic devices, implants and grafts

+∞

32.4

PD4DG

NOMESCO Finland

Very extensive MRI examination of abdominal aortta and vasculature of lower extremities with high intensity magnet

+∞

32.4

J01FF01

ATC

clindamycin; systemic

2.4

32.4

347

1752

J44.8

ICD-10 Finland

Other specified chronic obstructive pulmonary disease

2.9

31.9

226

902

I73.9

ICD-10 Finland

Peripheral vascular disease, unspecified

71.8

31.0

A10AC01

ATC

insulin (human); parenteral (insulins and analog. for injection, intermediate-acting)

3.5

30.6

152

471

C01AA05

ATC

digoxin; systemic

2.7

29.9

240

1031

PDQ05

NOMESCO Finland

Insertion of endovascular graft into infrarenal abdominal aorta

158.9

29.8

J18.9

ICD-10 Finland

Pneumonia, unspecified

2.1

29.7

429

2470

A49.9

ICD-10 Finland

Bacterial infection, unspecified

2.9

29.5

203

793

PDQ20

NOMESCO Finland

Insertion of endovascular graft into common iliac artery

+∞

29.3

I25.9

ICD-10 Finland

Chronic ischaemic heart disease, unspecified

2.6

29.2

246

1085

I71.2

ICD-10 Finland

Thoracic aortic aneurysm, without mention of rupture

298.7

28.9

C10AA01

ATC

simvastatin; oral

2.0

28.9

634

4313

FM1AE

NOMESCO Finland

Standard cardiac ultrasound examination

2.4

28.8

280

1333

PD5BD

NOMESCO Finland

Extensive CT of aorta

10.8

28.4

206

Kela drug reimbursment

Chronic coronary artery disease and dyslipidaemia associated with chronic coronary artery disease

2.2

27.8

376

2087

PD4HE

NOMESCO Finland

Postoperative lower extremity artery ultrasound examination with Doppler method

148.4

27.7

I63.9

ICD-10 Finland

Cerebral infarction, unspecified

2.6

27.6

232

1018

WX872

NOMESCO Finland

Intensive care

4.6

27.5

100

234

TPH04

NOMESCO Finland

Cathetrisation of vein

2.3

27.2

305

1553

I74.4

ICD-10 Finland

Embolism and thrombosis of arteries of extremities, unspecified

+∞

27.2

PFH62

NOMESCO Finland

Bypass from femoral or popliteal artery to proximal posterior tibial artery

+∞

27.2

PFU81

NOMESCO Finland

Thrombectomy or embolectomy of bypass from femoral or popliteal artery to infrapopliteal arteries

+∞

27.2

A10AB05

ATC

insulin aspart; parenteral (insulins and analog. for injection, fast-acting)

3.6

26.9

130

393

XF600

NOMESCO Finland

Bloodpressure measurement

3.8

26.7

118

331

PFH59

NOMESCO Finland

Bypass from femoral or popliteal artery to distal anterior tibial artery

+∞

26.1

PEU81

NOMESCO Finland

Thrombectomy or embolectomy of bypass from femoral to popliteal artery

+∞

26.1

XF400

NOMESCO Finland

ECG with 12 standard connections

2.3

25.8

272

1340

J01MA12

ATC

levofloxacin; systemic

2.3

25.6

283

1425

B01AB04

ATC

dalteparin; parenteral

4.0

25.5

107

287

QDB99

NOMESCO Finland

Other procedure for wound of skin of lower limb

29.1

25.5

FN1AC

NOMESCO Finland

Angiography of heart and/or coronary arteries

2.2

25.4

332

1804

Y83.9

ICD-10 Finland

Surgical procedure, unspecified as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure

6.4

25.3

112

WX882

NOMESCO Finland

High dependency care

6.0

25.1

125

PDE22

NOMESCO Finland

Thrombectomy or embolectomy of a. iliaca externa

+∞

25.1

5565

FHL

Femoropopliteal bypass surgery

+∞

25.1

PEN25

NOMESCO Finland

Plastic repair of superficial femoral artery

+∞

25.1

PFH66

NOMESCO Finland

Bypass from femoral or popliteal artery to dorsal artery of foot

+∞

25.1

T82.3

ICD-10 Finland

Mechanical complication of other vascular grafts

255.1

24.8

N03AX16

ATC

pregabalin; oral

2.2

24.4

299

1575

Z3231

NOMESCO Finland

Registered nurse

2.1

23.9

358

2052

315

Kela drug reimbursment

Clopidogrel

8.8

23.7

PG9AC

NOMESCO Finland

Arteriography with X-ray not elsewhere classified

34.1

23.4

E11.9

ICD-10 Finland

Type 2 diabetes mellitus, without complications

2.0

23.2

361

2094

205

Kela drug reimbursment

Chronic hypertension

1.9

23.1

479

3102

C09AA05

ATC

ramipril; oral

2.0

23.1

387

2312

PD4CM

NOMESCO Finland

Extensive MRI examination of abdominal aorta and vasculature of lower extremities with 3 Tesla magnet

+∞

23.0

PFP99

NOMESCO Finland

Percutaneous plastic repair of artery of lower leg

+∞

23.0

I80.29

ICD-10 Finland

Phlebitis and thrombophlebitis of other deep vessels of lower extremities

5.1

22.9

153

ZXA05

NOMESCO Finland

Left side

2.0

22.9

352

2033

L98.4

ICD-10 Finland

Chronic ulcer of skin, not elsewhere classified

8.4

22.6

C01DA14

ATC

isosorbide mononitrate; oral

2.1

22.3

327

1849

E11.8

ICD-10 Finland

Type 2 diabetes mellitus, with unspecified complications

2.7

22.3

167

681

C01DA02

ATC

glyceryl trinitrate; oral, oral aerosol, sublingual, transdermal

1.9

22.1

420

2624

PDE20

NOMESCO Finland

Thrombectomy or embolectomy of common iliac artery

+∞

21.9

PEU99

NOMESCO Finland

Other repair after previous reconstruction of femoral artery with branches and connection to popliteal artery

+∞

21.9

PFH58

NOMESCO Finland

Bypass from femoral or popliteal artery to proximal anterior tibial artery

+∞

21.9

PDH54

NOMESCO Finland

Bypass from aorta to bilateral femoral arteries

+∞

21.9

AN1

Coronary angiography

2.4

21.9

205

944

J01DB01

ATC

cefalexin; oral

1.9

21.9

892

7220

N18.9

ICD-10 Finland

Chronic kidney disease, unspecified

3.1

21.8

125

429

103

Kela drug reimbursment

Diabetes, insulin-treated

1.9

21.8

391

2387

PD1BD

NOMESCO Finland

Extensive CT of abdominal aorta and branches

18.8

21.8

PWC00

NOMESCO Finland

Reoperation for deep infection in surgery of peripheral vessels and lymphatic system

223.8

21.7

WX213

NOMESCO Finland

Lower leg blockade

31.8

21.5

JA1AE

NOMESCO Finland

Ultrasound examination of groin and abdominal wall

7.0

21.3

TK800

NOMESCO Finland

Hemodialysis

7.4

20.9

I72.3

ICD-10 Finland

Aneurysm and dissection of iliac artery

+∞

20.9

PEU85

NOMESCO Finland

Plastic repair of bypass from femoral to popliteal artery

+∞

20.9

PD7ZT

NOMESCO Finland

Stent grafting of abdominal aorta

+∞

20.9

PFU99

NOMESCO Finland

Other repair after previous reconstruction of blood flow in infrapopliteal arteries

+∞

20.9

WX700

NOMESCO Finland

Respiratory and circulatory monitoring

2.3

20.9

221

1079

PEC23

NOMESCO Finland

Suture of common femoral artery

30.6

20.6

I82.88

ICD-10 Finland

Embolism and thrombosis of other specified veins

6.9

20.3

WX306

NOMESCO Finland

Lumbar epidural anesthesy

4.1

20.1

205

I25.0

ICD-10 Finland

Atherosclerotic cardiovascular disease, so described

2.9

20.0

129

479

I25.2

ICD-10 Finland

Old myocardial infarction

2.6

19.9

161

683

I50.1

ICD-10 Finland

Left ventricular failure

3.1

19.9

114

391

R4110

NOMESCO Finland

Physiotherapy

2.0

19.9

311

1794

PFG26

NOMESCO Finland

Operation for aneurysm of popliteal artery

+∞

19.8

M04AA01

ATC

allopurinol; systemic

2.2

19.8

235

1209

B01AB10

ATC

tinzaparin; parenteral

3.1

19.6

112

383

R03BB04

ATC

tiotropium bromide; inhalant

2.5

19.6

170

748

C01DA08

ATC

isosorbide dinitrate; oral, oral aerosol, sublingual, transdermal

1.9

19.5

392

2474

PD1AE

NOMESCO Finland

Ultrasound examination of abdominal aortta

46.8

19.2

N02AE01

ATC

buprenorphine; parenteral, sublingual, transdermal

2.2

19.0

213

1066

J44.9

ICD-10 Finland

Chronic obstructive pulmonary disease, unspecified

3.0

18.9

113

399

PFH65

NOMESCO Finland

Bypass from femoral or popliteal artery to distal peroneal artery

+∞

18.8

I74.9

ICD-10 Finland

Embolism and thrombosis of unspecified artery

+∞

18.8

K55.0

ICD-10 Finland

Acute vascular disorders of intestine

+∞

18.8

I71.3

ICD-10 Finland

Abdominal aortic aneurysm, ruptured

+∞

18.8

I70.8

ICD-10 Finland

Atherosclerosis of other arteries

71.0

18.7

L89

ICD-10 Finland

Decubitus ulcer and pressure area

6.1

18.6

Z3226

NOMESCO Finland

Physiotherapist

2.1

18.5

226

1171

J01MA02

ATC

ciprofloxacin; systemic

1.8

18.4

492

3390

J01DA01

ATC

[U] cefalexin; systemic

1.7

18.4

711

5480

TKC20

NOMESCO Finland

Catheterisation of bladder

2.6

18.3

139

566

ZXA00

NOMESCO Finland

Right side

1.9

18.3

358

2226

ZXE40

NOMESCO Finland

More than seven and less than nine hours

5.7

18.3

ZXE00

NOMESCO Finland

One hour or less

1.8

18.2

449

3019

201

Kela drug reimbursment

Chronic cardiac insufficiency

2.6

18.1

138

563

FM1EE

NOMESCO Finland

Extensive structural and functional ultrasound examination of heart

2.0

18.0

275

1564

C03DA01

ATC

spironolactone; oral

2.3

17.9

187

904

I20.81

ICD-10 Finland

Other angina pectoris stenosed coronary artery

2.5

17.9

151

653

A10AE04

ATC

insulin glargine; parenteral

2.6

17.8

136

557

I72.8

ICD-10 Finland

Aneurysm and dissection of other specified arteries

+∞

17.7

I74.8

ICD-10 Finland

Embolism and thrombosis of other arteries

+∞

17.7

PDQ22

NOMESCO Finland

Insertion of endovascular graft into a. iliaca externa

+∞

17.7

FB1BD

NOMESCO Finland

Extensive CT examination of arteria pulmonalis

2.8

17.6

120

461

I69.3

ICD-10 Finland

Sequelae of cerebral infarction

2.4

17.6

156

695

PBE09

NOMESCO Finland

Thrombectomy or embolectomy of brachial artery

182.5

17.6

WX320

NOMESCO Finland

Spinalanesthesy

1.9

17.4

286

1665

I10

ICD-10 Finland

Essential (primary) hypertension

1.7

17.4

746

5882

A28

ICPC

Limited function/disability NOS

2.0

17.4

246

1352

I21.49

ICD-10 Finland

Acute subendocardial infarction unspecified coronary artery status

2.7

17.3

124

490

R06.0

ICD-10 Finland

Dyspnoea

1.9

17.0

313

1901

I70

ICD-10 Finland

Atherosclerosis

26.0

16.9

PG1AE

NOMESCO Finland

Ultrasound examination of artery not elsewher classified

26.0

16.9

QD9S1

NOMESCO Finland

Photography of skin or subcutaneous tissue in lower extremities, unspecified

19.6

16.9

PDH55

NOMESCO Finland

Bypass from iliac to femoral artery

+∞

16.7

PDG51

NOMESCO Finland

Bypass from aorta to iliac artery for aneurysm

+∞

16.7

PFP26

NOMESCO Finland

Percutaneous plastic repair of popliteal artery

+∞

16.7

PFN26

NOMESCO Finland

Plastic repair of popliteal artery

+∞

16.7

AA1AD

NOMESCO Finland

CT of head and brain

1.8

16.7

324

2001

PG1XE

NOMESCO Finland

Other ultrasound examination of blood vessel not elsewhere classified

20.4

16.4

C10AX09

ATC

ezetimibe; oral

2.5

16.4

137

589

C10AA05

ATC

atorvastatin; oral

1.7

16.3

477

3345

213

Kela drug reimbursment

Fat metabolism disorder associated with chronic coronary artery disease

2.4

16.1

151

691

N17.9

ICD-10 Finland

Acute renal failure, unspecified

3.4

16.1

237

I82.9

ICD-10 Finland

Embolism and thrombosis of unspecified vein

5.4

16.0

T82.7

ICD-10 Finland

Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts

33.8

15.8

T81.3

ICD-10 Finland

Disruption of operation wound, not elsewhere classified

5.4

15.7

C08CA01

ATC

amlodipine; oral

1.7

15.7

463

3246

E10.5

ICD-10 Finland

Type 1 diabetes mellitus, With peripheral circulatory complications

+∞

15.7

ZPB96

NOMESCO Finland

Other material in vessel transplant

+∞

15.7

XPX16

NOMESCO Finland

Ultrasound investigation of periferal vessel

+∞

15.7

ZPB20

NOMESCO Finland

Vene in its own postion

+∞

15.7

N02AA59

ATC

codeine, combinations excl. psycholeptics; systemic

1.7

15.4

476

3375

L17

ICPC

Foot/toe symptom/complaint

1.9

15.3

276

1652

ZX120

NOMESCO Finland

Intravenous

2.5

15.3

127

545

I65.2

ICD-10 Finland

Occlusion and stenosis of carotid artery

4.7

15.3

115

K28

ICPC

Limited function/disability (K)

5.3

15.2

L28

ICPC

Limited function/disability (L)

2.0

15.2

226

1261

ZPB32

NOMESCO Finland

Covered dacron

45.6

15.1

C08CA05

ATC

nifedipine; systemic

2.5

14.9

119

498

K78

ICPC

Atrial fibrillation/flutter

2.3

14.8

140

640

NH3AA

NOMESCO Finland

Foot and toes X-ray examination

2.9

14.6

324

I74.5

ICD-10 Finland

Embolism and thrombosis of iliac artery

+∞

14.6

44020

ICD-8 Finland

Arteriosclerosis, Of arteries of the extremities

+∞

14.6

I74.1

ICD-10 Finland

Embolism and thrombosis of other and unspecified parts of aorta

+∞

14.6

AB14W

NOMESCO Finland

+∞

14.6

PFU96

NOMESCO Finland

Re-bypass from femoral or popliteal artery to lower leg of foot

+∞

14.6

C09AA02

ATC

enalapril; systemic

1.8

14.6

301

1884

A10AE05

ATC

insulin detemir; parenteral

3.1

14.5

277

H02AB06

ATC

prednisolone; systemic

1.6

14.5

533

3941

SPAT1151

SPAT

Treatment of major wounds

8.0

14.4

M10.9

ICD-10 Finland

Gout, unspecified

2.6

14.3

107

434

Z2446

NOMESCO Finland

Social worker

2.9

14.1

307

A41.9

ICD-10 Finland

Sepsis, unspecified

3.4

14.0

213

A02BC02

ATC

pantoprazole; systemic

1.6

14.0

706

5646

E10.7

ICD-10 Finland

Type 1 diabetes mellitus, With multiple complications

7.2

13.9

WX602

NOMESCO Finland

Repeated or continuing anesthesia shots throug a catheter

2.7

13.9

370

ZXE50

NOMESCO Finland

More than nine and less than 12 hours

5.4

13.8

S18

ICPC

Laceration/cut

1.6

13.7

452

3235

I71.9

ICD-10 Finland

Aortic aneurysm of unspecified site, without mention of rupture

76.0

13.6

PDP20

NOMESCO Finland

Percutaneous plastic repair of common iliac artery

+∞

13.6

PET23

NOMESCO Finland

Injection of therapeutic agent into or percutaneous occlusion of femoral artery

+∞

13.6

PEG23

NOMESCO Finland

Operation for aneurysm of femoral artery

+∞

13.6

C07AB02

ATC

metoprolol; systemic

1.7

13.5

331

2175

QDG30

NOMESCO Finland

Delayed skin closure of surgical wound in lower limb

34.4

13.5

FM1BE

NOMESCO Finland

Cardiac ultrasound examination through oesophagus

2.9

13.5

306

JN3AE

NOMESCO Finland

Abdominal ultrasound examination

2.1

13.4

163

838

Angiography of the heart and coronary arteries

2.3

13.4

126

576

ZXE90

NOMESCO Finland

More than 22 hours

11.6

13.3

N02BE01

ATC

paracetamol; systemic, rectal

1.7

13.3

940

8157

Z49.1

ICD-10 Finland

Extracorporeal dialysis

9.2

13.2

I20.01

ICD-10 Finland

Unstable angina

3.6

12.9

172

I48.9

ICD-10 Finland

Atrial fibrillation and atrial flutter, unspecified

2.6

12.9

383

Y83.2

ICD-10 Finland

Surgical operation with anastomosis, bypass or graft as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure

50.5

12.9

J44.0

ICD-10 Finland

Chronic obstructive pulmonary disease with acute lower respiratory infection

2.7

12.7

353

A10AA02

ATC

3.8

12.6

144

I21.41

ICD-10 Finland

Acute subendocardial infarction stenosed coronary artery

2.8

12.6

313

I63.4

ICD-10 Finland

Cerebral infarction due to embolism of cerebral arteries

3.0

12.6

247

R60.0

ICD-10 Finland

Localized oedema

2.1

12.6

148

750

I79.2*E11.5

ICD-10 Finland

Non-insulin-dependent diabetes mellitus - Diabetic peripheral angiopathy

+∞

12.5

PG2YT

NOMESCO Finland

Implantation of arterial endoprothesis not elsewhere classified

+∞

12.5

PDG05

NOMESCO Finland

Operation on infrarenal abdominal aorta for aneurysm

+∞

12.5

PDU81

NOMESCO Finland

Thrombectomy or embolectomy in bypass from infrarenal abdominal aorta or iliac artery

+∞

12.5

PE3YT

NOMESCO Finland

Femoral and popliteal artery stentgraft therapy

+∞

12.5

A09

ICD-10 Finland

Other gastroenteritis and colitis of infectious and unspecified origin

2.0

12.5

183

1012

PWA00

NOMESCO Finland

Repair of wound dehiscence in surgery of peripheral vessels and lymphatic system

131.3

12.5

SPAT1099

SPAT

Measurement of blood pressure with Doppler ultrasound device

3.8

12.4

141

A10BB12

ATC

glimepiride; oral

2.2

12.4

129

619

ZXE03

NOMESCO Finland

Procedure duration 20 to 29 minutes

2.9

12.4

266

D64.9

ICD-10 Finland

Anaemia, unspecified

2.0

12.3

159

837

Z95.1

ICD-10 Finland

Presence of aortocoronary bypass graft

2.8

12.3

291

FN1YT

NOMESCO Finland

Percutaneous insertion of coronary artery stent

2.5

12.1

409

QX2XE

NOMESCO Finland

Ultrsound examination of soft tissue not elsewhere classified

4.3

12.1

105

M86.9

ICD-10 Finland

Osteomyelitis, unspecified

27.0

12.1

T79.6

ICD-10 Finland

Traumatic ischaemia of muscle

21.5

12.0

D68.8

ICD-10 Finland

Other specified coagulation defects

9.4

12.0

B01AC07

ATC

dipyridamole; systemic

2.3

11.9

111

503

T36

ICD-10 Finland

Poisoning by systemic antibiotics

4.2

11.9

107

R10.4

ICD-10 Finland

Other and unspecified abdominal pain

1.6

11.7

342

2348

N07BA03

ATC

varenicline; oral

3.7

11.7

139

JN1AE

NOMESCO Finland

Ultrasound examination of upper part of abdomen

2.4

11.6

430

TPH20

NOMESCO Finland

Insertion of central venous catheter through subclavian or brachiocephalic vein

4.0

11.6

119

N08.39*E11.2

ICD-10 Finland

Non-insulin-dependent diabetes mellitus - Diabetic nephropathy

6.0

11.5

3013

Kela drug reimbursment

Rivaroxaban for the treatment of coronary artery disease

+∞

11.5

PGU81

NOMESCO Finland

Thrombectomy or embolectomy of extra-anatomic bypass

+∞

11.5

PD3BT

NOMESCO Finland

Pelvic artery extensive PTA

+∞

11.5

PG1AT

NOMESCO Finland

PTA of artery not elsewhere classified

+∞

11.5

XP60W

NOMESCO Finland

+∞

11.5

PD4BG

NOMESCO Finland

MRI examination of abdominal aortta and vasculature of lower extremities with high intensity magnet

121.1

11.4

Z89.6

ICD-10 Finland

Acquired absence of leg above knee

121.1

11.4

ZXD10

NOMESCO Finland

Scheduled procedure

1.6

11.4

418

3037

4273A

ICD-9 Finland

Cardiac dysrhythmias, Atrial fibrillation and flutter

3.2

11.3

191

A10BA02

ATC

metformin; oral

1.6

11.3

352

2454

C09DX04

ATC

valsartan and sacubitril; oral

10.7

11.3

UJD10

NOMESCO Finland

Esophagoscopy, gastroscopy and duodenoscopy

1.6

11.2

326

2227

N08.39*E10.2

ICD-10 Finland

Insulin-dependent diabetes mellitus - Diabetic nephropathy

25.3

11.1

AN4

Balloon angioplasty and drug eluding stent

3.1

11.1

194

K99

ICPC

Cardiovascular disease other

3.6

11.1

145

FN1BC

NOMESCO Finland

Extensive angiography of hear and/or coronary arteries

2.5

11.0

376

127

Kela drug reimbursment

Transplant complication

7.9

10.9

A12BA01

ATC

potassium chloride; oral

2.2

10.8

107

501

A10AB01

ATC

insulin (human); parenteral (insulins and analog. for injection, fast-acting)

3.9

10.8

112

A11CC03

ATC

alfacalcidol; systemic

4.3

10.8

A41.0

ICD-10 Finland

Sepsis due to Staphylococcus aureus

4.3

10.8

289

Kela drug reimbursment

Combination product containing sacubitril and valsartan

8.9

10.8

215

Kela drug reimbursment

Diabetes, non-insulin-treated

1.7

10.7

271

1780

280

Kela drug reimbursment

Clopidogrel

4.6

10.7

PC1AC

NOMESCO Finland

Angiography of aorta and abdominal arteries

60.5

10.6

R50.9

ICD-10 Finland

Fever, unspecified

1.9

10.6

161

900

QBB10

NOMESCO Finland

Major dressing of wound of skin of trunk

3.5

10.6

140

207

Kela drug reimbursment

Chronic arrhythmias

1.7

10.5

223

1390

QDA10

NOMESCO Finland

Incision of skin of lower limb

14.3

10.5

T87.4

ICD-10 Finland

Infection of amputation stump

110.9

10.4

5579

FHL

Other measure in this category

+∞

10.4

5563

FHL

Aortopemoral bypass surgery

+∞

10.4

I72.9

ICD-10 Finland

Aneurysm and dissection of unspecified site

+∞

10.4

NFQ48

NOMESCO Finland

Revision of exarticulation or amputation stump of hip or femur

+∞

10.4

PFH64

NOMESCO Finland

Bypass from femoral or popliteal artery to proximal peroneal artery

+∞

10.4

I20.00

ICD-10 Finland

Unstable angina

2.9

10.4

230

FNA01

NOMESCO Finland

Anastomosis to coronary artery from internal mammary artery, one distal anastamosis

2.5

10.4

342

SPAT1229

SPAT

Assessment of need for aid

2.1

10.3

115

569

X59

ICD-10 Finland

Exposure to unspecified factor

1.8

10.0

175

1025

L04AD02

ATC

tacrolimus; systemic (calcineurin inhibitors)

14.7

10.0

ZXE02

NOMESCO Finland

Procedure duration 10 to 19 minutes

3.0

10.0

196

A10AA01

ATC

4.8

10.0

RS221

NOMESCO Finland

6.4

9.9

L03.1

ICD-10 Finland

Cellulitis of other parts of limb

4.0

9.9

N10

ICD-10 Finland

Acute tubulo-interstitial nephritis

1.8

9.8

180

1075

I20.99

ICD-10 Finland

Angina pectoris, unspecified

2.1

9.8

115

580

B03XA02

ATC

darbepoetin alfa; parenteral

5.0

9.8

SPAT1070

SPAT

Doppler ultrasound examination of blood flow in arteries of lower extremity

4.4

9.7

L04AA06

ATC

mycophenolic acid; systemic

6.6

9.7

I80.0

ICD-10 Finland

Phlebitis and thrombophlebitis of superficial vessels of lower extremities

3.1

9.7

167

K94

ICPC

Phlebitis/thrombophlebitis

4.8

9.7

123

Kela drug reimbursment

Chronic disorders of vitamin D metabolism

4.0

9.7

K29

ICPC

Cardiovascular sympt/complt other

2.8

9.7

232

Z2221

NOMESCO Finland

Medical doctor

1.6

9.6

280

1908

Y83.8

ICD-10 Finland

Other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure

3.9

9.5

QXB99

NOMESCO Finland

Other procedure to treat skin wound, unspecified location

5.0

9.4

I70.1

ICD-10 Finland

Atherosclerosis of renal artery

100.7

9.4

W01

ICD-10 Finland

Fall on same level from slipping, tripping and stumbling

1.5

9.4

369

2700

I74.0

ICD-10 Finland

Embolism and thrombosis of abdominal aorta

+∞

9.4

PDP22

NOMESCO Finland

Percutaneous plastic repair of a. iliaca externa

+∞

9.4

PFW99

NOMESCO Finland

Other connection from femoral artery to infrapopliteal arteries or operations on popliteal artery and arteries of lower leg and foot

+∞

9.4

PWW99

NOMESCO Finland

Other reoperation on peripheral vessels or lymphatic system

+∞

9.4

PD3ZT

NOMESCO Finland

Stent grafting of pelvic artery

+∞

9.4

PX1AE

NOMESCO Finland

+∞

9.4

J01EE01

ATC

sulfamethoxazole and trimethoprim; systemic

2.4

9.4

323

I80.1

ICD-10 Finland

Phlebitis and thrombophlebitis of femoral vein

4.5

9.4

SPAT1253

SPAT

Initiation, adjustment, discontinuation or repetition of medication

1.6

9.3

325

2310

138

Kela drug reimbursment

Severe anaemia associated with chronic renal failure

4.3

9.3

J44.1

ICD-10 Finland

Chronic obstructive pulmonary disease with acute exacerbation, unspecified

2.8

9.2

220

S91.3

ICD-10 Finland

Open wound of other parts of foot

4.7

9.2

SPAT1255

SPAT

Intravenous administration of medicine

2.3

9.2

371

E10.2

ICD-10 Finland

Type 1 diabetes mellitus, With renal complications

13.8

9.2

4019X

ICD-9 Finland

Essential hypertension, Unspecified

2.6

9.2

264

G45.9

ICD-10 Finland

Transient cerebral ischaemic attack, unspecified

2.0

9.2

123

656

TPH30

NOMESCO Finland

Insertion of central venous catheter through periferal vein

5.2

9.1

E11.00

ICD-10 Finland

Non-insulin dependent diabetes diabetic hypoglycaemic coma

2.7

9.1

234

ZXE05

NOMESCO Finland

Procedure duration 40 to 49 minutes

2.8

9.1

217

Z94.0

ICD-10 Finland

Kidney transplant status

9.1

9.0

JN3BD

NOMESCO Finland

Extensive abdominal CT

1.9

9.0

126

684

SPAT1149

SPAT

Suture or treatment of traumatic wound

1.8

9.0

156

911

I80.8

ICD-10 Finland

Phlebitis and thrombophlebitis of other sites

5.1

9.0

R02

ICD-10 Finland

Gangrene, not elsewhere classified

24.2

8.9

A10BB01

ATC

glibenclamide; oral

2.2

8.8

449

I25.5

ICD-10 Finland

Ischaemic cardiomyopathy

3.4

8.8

124

KA1AE

NOMESCO Finland

Kidney ultrasound examination

3.7

8.8

103

X57

ICD-10 Finland

Unspecified privation

3.9

8.8

I83.0

ICD-10 Finland

Varicose veins of lower extremities with ulcer

3.8

8.8

A10AD05

ATC

insulin aspart; parenteral (insulins and analog. for injection, intermediate- or long-acting comb. with fast-acting)

3.3

8.7

130

A41.1

ICD-10 Finland

Sepsis due to other specified staphylococcus

14.1

8.7

WX214

NOMESCO Finland

Plexus blockade at the ankle

14.1

8.7

R95

ICPC

Chron obstructive pulmonary disease

3.4

8.7

125

PBL09

NOMESCO Finland

Construction of arteriovenous fistula from brachial artery

50.3

8.7

PEA23

NOMESCO Finland

Exploration of femoral artery

50.3

8.7

N05CF01

ATC

zopiclone; oral

1.5

8.7

395

2975

ZXE04

NOMESCO Finland

Procedure duration 30 to 39 minutes

2.4

8.6

305

A10AB04

ATC

insulin lispro; parenteral (insulins and analog. for injection, fast-acting)

3.9

8.6

J15.9

ICD-10 Finland

Bacterial pneumonia, unspecified

1.8

8.5

142

816

E78.01

ICD-10 Finland

Pure hypercholesterolaemia

1.6

8.5

231

1537

TFC00

NOMESCO Finland

Catheterisation of right atrium or ventricle

4.2

8.5

R55

ICD-10 Finland

Syncope and collapse

1.8

8.5

145

842

D68.9

ICD-10 Finland

Coagulation defect, unspecified

20.2

8.5

V03AE02

ATC

sevelamer; oral

20.2

8.5

I20.09

ICD-10 Finland

Unstable angina

2.1

8.4

432

QDG00

NOMESCO Finland

Debridement of bedsore of lower limb

90.6

8.4

PG1CG

NOMESCO Finland

Extensive MRI examination of vasculature with high intensity magnet not elsewhere classified

90.6

8.4

L14

ICPC

Leg/thigh symptom/complaint

2.2

8.4

398

J01MA14

ATC

moxifloxacin; systemic

2.1

8.4

501

XQ858

NOMESCO Finland

Oxygen partial pressure measurement

6.8

8.4

P01AB01

ATC

metronidazole; oral, rectal

1.5

8.3

357

2646

XX4FT

NOMESCO Finland

Exchange to other catheter with radiological guidance

+∞

8.3

PF1YT

NOMESCO Finland

Stenting of tibial or ankle arteries

+∞

8.3

K55.1

ICD-10 Finland

Chronic vascular disorders of intestine

+∞

8.3

PGH44

NOMESCO Finland

Bypass from axillary to bilateral femoral arteries

+∞

8.3

PFH60

NOMESCO Finland

Bypass from femoral or popliteal artery to tibioperoneal trunk

+∞

8.3

G54.6

ICD-10 Finland

Phantom limb syndrome with pain

+∞

8.3

PEU91

NOMESCO Finland

Excision of bypass from femoral to popliteal artery

+∞

8.3

TPH90

NOMESCO Finland

Removal of fixed intravenous catheter

6.3

8.3

25000

ICD-8 Finland

Diabetes mellitus, Sine complicatione

3.2

8.3

130

H02AB07

ATC

prednisone; oral

1.8

8.3

160

966

T90

ICPC

Diabetes non-insulin dependent

1.6

8.3

252

1727

WX002

NOMESCO Finland

Sedation and analgesia

1.6

8.2

211

1386

R53

ICD-10 Finland

Malaise and fatigue

1.6

8.2

232

1561

A04.7

ICD-10 Finland

Enterocolitis due to Clostridium difficile

3.2

8.2

131

Z76.9

ICD-10 Finland

Person encountering health services in unspecified circumstances

2.2

8.2

367

R26.2

ICD-10 Finland

Difficulty in walking, not elsewhere classified

5.7

8.1

N18.8

ICD-10 Finland

Other chronic renal failure

3.2

8.1

132

381

Kela drug reimbursment

Combination product containing sacubitril and valsartan

8.2

8.1

I20.90

ICD-10 Finland

Angina pectoris, unspecified

2.3

8.1

316

A12AA04

ATC

calcium carbonate; oral

4.9

8.1

N28.0

ICD-10 Finland

Ischaemia and infarction of kidney

33.6

8.1

FN1AT

NOMESCO Finland

Endovascular dilatation of coronary arteries (PTCA)

2.2

8.1

371

PAF14

NOMESCO Finland

Thrombendarterectomy of internal carotid artery

3.9

8.0

AN2

Balloon angioplasty, including several vessels

3.0

7.9

146

JN3AA

NOMESCO Finland

Abdominal X-ray examination without contrast

2.3

7.8

296

L02.4

ICD-10 Finland

Cutaneous abscess, furuncle and carbuncle of limb

3.3

7.8

114

FN1BT

NOMESCO Finland

Extensive endovascular dilatation of coronary (PTCA) arteries

3.2

7.8

120

WX404

NOMESCO Finland

Intravenous generell anesthesy

1.6

7.7

188

1217

B01AF02

ATC

apixaban; oral

1.8

7.7

133

776

I80.9

ICD-10 Finland

Phlebitis and thrombophlebitis of unspecified site

4.4

7.7

J20.9

ICD-10 Finland

Acute bronchitis, unspecified

1.6

7.6

190

1235

A41.5

ICD-10 Finland

Sepsis due to other Gram-negative organisms

2.7

7.6

201

TPX10

NOMESCO Finland

Implantation of vascular injection port

3.3

7.6

111

SPAT1083

SPAT

Initiation and monitoring of IV fluid therapy

2.5

7.6

228

SPAT1222

SPAT

Counselling/guidance promoting independent living

1.6

7.6

188

1220

PC1BC

NOMESCO Finland

Extensive angiography of aorta and abdominal arteries

25.2

7.6

A07AA09

ATC

vancomycin; oral

5.2

7.6

J01CF05

ATC

flucloxacillin; systemic

3.0

7.6

148

G72.8

ICD-10 Finland

Other specified myopathies

3.7

7.5

XF603

NOMESCO Finland

Direct intraarterial blood pressure measurement

2.8

7.5

164

N02AC04

ATC

dextropropoxyphene; oral

2.2

7.4

324

379

Kela drug reimbursment

Apixaban, dabigatran, edoxaban and rivaroxaban for the long-term prevention of recurrent deep veinthrombosis and pulmonary embolism

3.5

7.4

XCK10

NOMESCO Finland

Photography of fundus of eye

1.8

7.4

122

699

WX000

NOMESCO Finland

Monitoring vital functions without anesthesy

2.7

7.4

189

N02AJ06

ATC

codeine and paracetamol; systemic

1.5

7.4

321

2380

EBA15

NOMESCO Finland

Extraction of large number of teeth

2.8

7.4

175

JN4BD

NOMESCO Finland

Extensive body CT

1.8

7.4

132

779

E10.9

ICD-10 Finland

Type 1 diabetes mellitus, Without complications

3.0

7.3

131

B01AC30

ATC

platelet aggregation inhibitors excl. heparin - combinations

1.9

7.3

103

558

ZXE60

NOMESCO Finland

More than 12 and less than 15 hours

6.9

7.3

S78.1

ICD-10 Finland

Traumatic amputation at level between hip and knee

+∞

7.3

NGQ10

NOMESCO Finland

Exarticulation of knee

+∞

7.3

PEQ23

NOMESCO Finland

Insertion of endovascular graft into femoral artery

+∞

7.3

PGU99

NOMESCO Finland

Other repair of extra-anatomic bypass

+∞

7.3

XP601

NOMESCO Finland

+∞

7.3

PDG54

NOMESCO Finland

Bypass from aorta to femoral artery for aneurysm

+∞

7.3

296

Kela drug reimbursment

Rivaroxaban for the treatment of coronary heart disease

+∞

7.3

NGQ48

NOMESCO Finland

Revision of exarticulation or amputation stump of knee or lower leg

+∞

7.3

PG1DM

NOMESCO Finland

Very extensive MRI examination of vasculature not elsewhere classified with 3 Tesla magnet

+∞

7.3

JN3AD

NOMESCO Finland

Abdominal CT examination

2.0

7.3

432

SPAT1254

SPAT

Administration of medicine

1.6

7.2

177

1145

E87.5

ICD-10 Finland

Hyperkalaemia

3.6

7.2

I50

ICD-10 Finland

Heart failure

2.5

7.2

216

C02AC05

ATC

moxonidine; oral

2.4

7.1

235

L84

ICD-10 Finland

Corns and callosities

3.1

7.1

123

I26.9

ICD-10 Finland

Pulmonary embolism without mention of acute cor pulmonale

2.1

7.1

407

QDE35

NOMESCO Finland

Repair of skin defect in lower limb after surgery or injury

12.1

7.1

PD5AD

NOMESCO Finland

CT of aorta

4.3

7.0

E11.2

ICD-10 Finland

Type 2 diabetes mellitus, with renal complications

2.6

7.0

183

WX402

NOMESCO Finland

General anaesthesia

1.7

7.0

139

848

SPAT1230

SPAT

Aid fitting and borrowing and monitoring of use

1.6

7.0

194

1298

I11.9

ICD-10 Finland

Hypertensive heart disease without (congestive) heart failure

2.2

6.9

306

R11

ICD-10 Finland

Nausea and vomiting

2.0

6.9

445

R4180

NOMESCO Finland

Podiatric therapy

5.9

6.9

C02EA02

ATC

2.0

6.9

406

QX3HE

NOMESCO Finland

Ultrsound examination of lesion close to skin

4.4

6.9

RS220

NOMESCO Finland

4.8

6.9

D50.9

ICD-10 Finland

Iron deficiency anaemia, unspecified

1.9

6.8

494

N03AX12

ATC

gabapentin; oral

1.7

6.8

144

893

PD5CD

NOMESCO Finland

Very extensive CT angiography of aorta

8.3

6.8

I15.1

ICD-10 Finland

Hypertension secondary to other renal disorders

6.7

6.8

Y88.3

ICD-10 Finland

Sequelae of surgical and medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure

2.9

6.8

137

H3603, E113

ICD-10 Finland

6.1

6.8

PD5CG

NOMESCO Finland

Extensive MRI examination of thoracal and abdominal aortta with high intensity magnet

40.3

6.8

RJ414

NOMESCO Finland

40.3

6.8

SPAT1217

SPAT

Assessment of need for services (elderly/care support)

1.8

6.8

106

600

XF612

NOMESCO Finland

Measurement of central venous pressure

16.8

6.7

C10AA04

ATC

fluvastatin; oral

1.8

6.7

120

709

Z72.0

ICD-10 Finland

Tobacco use

3.8

6.7

V03AE01

ATC

polystyrene sulfonate; oral

4.5

6.7

N19

ICD-10 Finland

Unspecified kidney failure

2.4

6.7

214

Z49.0

ICD-10 Finland

Preparatory care for dialysis

6.5

6.6

190

Kela drug reimbursment

Lanthanum carbonate, sevelamer and sucroferric oxyhydroxide

7.9

6.6

SPAT1262

SPAT

Handing over of treatment supplies

1.6

6.6

201

1374

SPAT1156

SPAT

Guidance concerning treatment of rash and skin

1.6

6.6

154

984

A98

ICPC

Health maint/preventive medicine

0.7

6.6

778

8640

WW500

NOMESCO Finland

Blood transfusion

2.5

6.6

209

QWA00

NOMESCO Finland

Repair of wound dehiscence in surgery of skin

10.1

6.5

N05CD07

ATC

temazepam; oral

1.6

6.5

183

1228

N17.8

ICD-10 Finland

Other acute renal failure

4.0

6.5

ZXD30

NOMESCO Finland

Difficulties in perfomrming procedure

2.5

6.5

203

WX212

NOMESCO Finland

Femoral plexus blockade

3.2

6.4

Z03.9

ICD-10 Finland

Observation for suspected disease or condition, unspecified

1.6

6.4

172

1139

351

Kela drug reimbursment

Apixaban, dabigatran, edoxaban and rivaroxaban for the treatment of atrial fibrillation

1.6

6.4

163

1065

FNC30

NOMESCO Finland

Aorto-coronary venous bypass with three distal anastomoses

3.3

6.4

PD1CD

NOMESCO Finland

Very extensive CT of abdominal aorta and branches

14.4

6.4

R03AK06

ATC

salmeterol and fluticasone; inhalant

1.6

6.4

152

974

T81.9

ICD-10 Finland

Unspecified complication of procedure

3.8

6.4

N02AB03

ATC

fentanyl; nasal, sublingual, transdermal

2.1

6.4

339

KAS10

NOMESCO Finland

Allogenic transplantation of kidney from cadaver donor

8.2

6.3

C08CA02

ATC

felodipine; oral

1.7

6.3

128

785

PB1DE

NOMESCO Finland

Upper extremity arteries ultrasound examination with Doppler method

11.1

6.3

T81.7

ICD-10 Finland

Vascular complications following a procedure, not elsewhere classified

9.3

6.3

J45.9

ICD-10 Finland

Asthma, unspecified

1.6

6.3

179

1204

PGU91

NOMESCO Finland

Excision of extra-anatomic bypass

+∞

6.3

I79.2*E10.5

ICD-10 Finland

Insulin-dependent diabetes mellitus - Diabetic peripheral angiopathy

+∞

6.3

I71.00

ICD-10 Finland

Dissecting aneurysm of aorta (ruptured) [any part]

+∞

6.3

PFH67

NOMESCO Finland

Bypass from femoral or popliteal artery to posterior tibial artery in foot

+∞

6.3

AB18W

NOMESCO Finland

+∞

6.3

5568

FHL

Femorofemoral bypass surgery

+∞

6.3

I51.3

ICD-10 Finland

Intracardiac thrombosis, not elsewhere classified

+∞

6.3

I77.8

ICD-10 Finland

Other specified disorders of arteries and arterioles

+∞

6.3

5566

FHL

Femorotibial bypass surgery

+∞

6.3

5562

FHL

Reconstruction of the aortoil cabbage area

+∞

6.3

PEW99

NOMESCO Finland

Other operation on femoral artery with branches and connection to popliteal artery

+∞

6.3

I702, L97

ICD-10 Finland

+∞

6.3

T87.6

ICD-10 Finland

Other and unspecified complications of amputation stump

+∞

6.3

PG5AC

NOMESCO Finland

Contrast examination of injection gate to artery or vein

+∞

6.3

I77.9

ICD-10 Finland

Disorder of arteries and arterioles, unspecified

+∞

6.3

PDU84

NOMESCO Finland

Plastic repair of bypass from infrarenal abdominal aorta or iliac artery

+∞

6.3

F10.1

ICD-10 Finland

Mental and behavioural disorders due to use of alcohol, Harmful use

2.2

6.2

287

I42.0

ICD-10 Finland

Dilated cardiomyopathy

2.7

6.2

150

J96.0

ICD-10 Finland

Acute respiratory failure

4.0

6.2

XF655

NOMESCO Finland

Measurement of heart muscle perfusion with exercise

2.7

6.2

152

I35.0

ICD-10 Finland

Aortic (valve) stenosis

1.9

6.2

481

L04AA01

ATC

[U] ciclosporin; systemic

4.5

6.2

S91.1

ICD-10 Finland

Open wound of toe(s) without damage to nail

4.5

6.2

R03AL01

ATC

fenoterol and ipratropium bromide; inhalant

3.0

6.2

113

C02CA01

ATC

prazosin; oral

3.0

6.2

113

H3603, E103

ICD-10 Finland

7.7

6.1

WX702

NOMESCO Finland

Supraglottic ventilation device

2.4

6.1

205

WZC10

NOMESCO Finland

Extensive specialist consultion with written report

2.4

6.1

198

TFP20

NOMESCO Finland

Cardiodefibrillation

1.8

6.1

521

R52.0

ICD-10 Finland

Acute pain

3.1

6.1

C09BA02

ATC

enalapril and diuretics; systemic

1.8

6.1

104

607

Catheterization and pressure measurement of the left side of the heart

2.9

6.1

124

1CX08

NOMESCO Finland

8.6

6.1

Z5132

NOMESCO Finland

Nursing associate professional

8.6

6.1

ZXE01

NOMESCO Finland

Procedure duration 0 to 9 minutes

4.9

6.1

AA1

Conventional CABG

3.0

6.0

109

I26.0

ICD-10 Finland

Pulmonary embolism with mention of acute cor pulmonale

3.0

6.0

109

Z95.8

ICD-10 Finland

Presence of other cardiac and vascular implants and grafts

10.1

6.0

QBB05

NOMESCO Finland

Revision of wound of skin of trunk

5.2

6.0

NAME	I9_ARTEMBTHRLOW
CONTROL_EXCLUDE	I9_DOAAC
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX
INCLUDE
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10	I743
HD_ICD_9	4442A
HD_ICD_8	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10	I743
COD_ICD_9	4442A
COD_ICD_8	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

Parameter	HR [95% CI]	p-value
I9_ARTEMBTHRLOW	2.851 [2.42, 3.37]	< 0.001
Birth year	0.994 [0.99, 1.0]	0.168

Parameter	HR [95% CI]	p-value
I9_ARTEMBTHRLOW	2.71 [2.34, 3.13]	< 0.001
Birth year	0.99 [0.98, 1.0]	0.033

N-year risk	Females	Males
1	0.196%	0.666%
5	1.632%	3.398%
10	3.837%	8.646%
15	7.118%	16.2%
20	12.897%	25.911%

Arterial embolism and thrombosis of lower extremity artery

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

1. Apply sex-specific rule

2. Check conditions

3. Check pre-conditions, main-only, mode, registry filters

4. Check minimum number of events

5. Include endpoints

6. Filter based on genotype QC (FinnGen only)

Similar endpoints

Case counts by codes

Summary Statistics

-FinRegistry-

Key figures

-FinnGen-

Key figures

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS (R11)

Matched cohort

Mortality – FinRegistry

Association

Females

Males

Mortality risk

Relationships between endpoints