Arterial embolism and thrombosis of lower extremity artery

I9_ARTEMBTHRLOW

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 I74.3
  • Hospital discharge: ICD-9 4442A
  • Cause of death: ICD-10 I74.3
  • Cause of death: ICD-9 4442A

2 out of 7 registries used, show all original rules.

1326

4. Check minimum number of events

None

1326

5. Include endpoints

None

1326

6. Filter based on genotype QC (FinnGen only)

1326

Control definitions (FinnGen only)

Control exclude
I9_DOAAC

Extra metadata

Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
I74
Name in latin
Embolia arteriarum membrorum inferiorum

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 15872 7887 7734
Only index persons 9951 4973 4978
Unadjusted period prevalence (%)
Whole population 0.22 0.23 0.22
Only index persons 0.19 0.18 0.19
Median age at first event (years)
Whole population 75.44 80.10 70.77
Only index persons 74.25 79.43 69.07

-FinnGen-

Key figures

All Female Male
Number of individuals 1326 510 816
Unadjusted period prevalence (%) 0.29 0.17 0.36
Median age at first event (years) 70.09 70.64 69.75

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
1204
Matched controls
12044
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
I70.2
ICD-10 Finland
Atherosclerosis of arteries of extremities
386.7
323.0
766
54
I74.3
ICD-10 Finland
Embolism and thrombosis of arteries of lower extremities
14477.3
323.0
1114
8
XPX99
NOMESCO Finland
Other diagnostic examination of periferal vessel
25.9
266.5
385
214
PD4AC
NOMESCO Finland
Arterigography of lower extremity with X-ray
318.5
166.2
165
6
PD4BC
NOMESCO Finland
Extensive arterigography of lower extremity with X-ray
833.5
152.8
147
*
PD4CG
NOMESCO Finland
Extensive MRI examination of abdominal aortta and vasculature of lower extremities with high intensity magnet
341.4
150.3
149
5
NFQ20
NOMESCO Finland
Amputation of femur
814.1
149.5
144
*
PEE23
NOMESCO Finland
Thrombectomy or embolectomy of femoral artery
1590.6
147.0
140
*
NGM10
NOMESCO Finland
Fasciotomy of of knee or lower leg
106.8
146.2
158
17
B01AA03
ATC
warfarin; systemic
5.1
143.8
648
2251
PEH57
NOMESCO Finland
Bypass from femoral artery to popliteal artery below knee
+∞
143.6
135
*
QDB10
NOMESCO Finland
Major dressing of wound of skin of lower limb
18.3
143.4
230
153
PEF23
NOMESCO Finland
Thrombendarterectomy of femoral artery
1517.1
141.6
135
*
PFE26
NOMESCO Finland
Thrombectomy or embolectomy of popliteal artery
1366.4
128.6
123
*
PEH56
NOMESCO Finland
Bypass from femoral to popliteal artery above knee
+∞
128.5
121
*
PD4DE
NOMESCO Finland
Lower extremity artery ultrasound examination with Doppler method
96.5
125.1
137
16
PG1UT
NOMESCO Finland
Percutaneous aspiration throbectomy
440.0
122.0
120
*
I70.9
ICD-10 Finland
Generalized and unspecified atherosclerosis
268.5
120.2
121
5
PEE25
NOMESCO Finland
Thrombectomy or embolectomy of superficial femoral artery
1243.7
117.8
113
*
PE1AT
NOMESCO Finland
Femoral artery PTA
601.7
112.8
110
*
4442A
ICD-9 Finland
Arterial embolism and thrombosis, Of arteries of the extremities
+∞
104.7
99
*
PF1AT
NOMESCO Finland
Intravascular dilatation of arteries of knee, lower leg and ankle (PTA)
+∞
101.5
96
*
PD4BD
NOMESCO Finland
Extensive CT of lower extremity arteries
+∞
99.3
94
*
PD3YT
NOMESCO Finland
Pelvic artery PTA with stent
993.1
95.3
92
*
B01AC04
ATC
clopidogrel; oral
4.4
93.3
409
1247
PD4CC
NOMESCO Finland
Very extensive arterigography of lower extremity with X-ray
969.7
93.1
90
*
PG1ST
NOMESCO Finland
Endovascular arterial thrombolysis with radiological guidance not elsewhere classified
+∞
92.9
88
*
I71.4
ICD-10 Finland
Abdominal aortic aneurysm, without mention of rupture
150.4
92.5
97
7
4402A
ICD-9 Finland
Atherosclerosis, Of native arteries of the extremities
+∞
90.8
86
*
PE1YT
NOMESCO Finland
Femoral or popliteal artery PTA with stent
923.2
88.9
86
*
E11.5
ICD-10 Finland
Type 2 diabetes mellitus, with peripheral circulatory complications
100.7
85.3
93
10
NHQ40
NOMESCO Finland
Amputation of toe
+∞
84.4
80
*
QDB05
NOMESCO Finland
Revision of wound of skin of lower limb
19.4
81.4
126
72
I72.4
ICD-10 Finland
Aneurysm and dissection of artery of lower extremity
+∞
79.0
75
*
PD4ST
NOMESCO Finland
Endovascular thrombolysis of pelvic and lower extremity arteries
+∞
78.0
74
*
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
5.1
76.5
271
646
PFE99
NOMESCO Finland
Thrombectomy or embolectomy of artery of lower leg or foot
774.2
75.1
73
*
PG1DE
NOMESCO Finland
Other extensive ultrasound examination of artery
11.3
74.1
145
144
C03CA01
ATC
furosemide; systemic
3.0
70.8
655
3419
ZPB22
NOMESCO Finland
Autograft of vein
+∞
69.4
66
*
L97
ICD-10 Finland
Ulcer of lower limb, not elsewhere classified
11.4
65.1
126
122
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
3.7
64.9
335
1126
PEN23
NOMESCO Finland
Plastic repair of femoral artery
340.9
64.1
64
*
B01AB05
ATC
enoxaparin; parenteral
3.0
61.9
498
2305
XPX00
NOMESCO Finland
Intraoperative angiography
628.5
61.3
60
*
XPX08
NOMESCO Finland
Intraoperative flow measurement
67.4
61.0
70
11
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
4.7
59.7
223
550
I50.9
ICD-10 Finland
Heart failure, unspecified
3.2
56.6
377
1515
TPH07
NOMESCO Finland
Cathetrisation of artery
4.1
54.9
238
676
PEE24
NOMESCO Finland
Thrombectomy or embolectomy of deep femoral artery
+∞
52.5
50
*
ZZA00
NOMESCO Finland
Split skin graft
8.7
51.9
116
145
QDG20
NOMESCO Finland
Operation for chronic ulcer or fistula of skin of lower limb
40.3
51.8
65
17
WX408
NOMESCO Finland
General anesthesy, balanced
2.9
50.9
404
1799
NGQ20
NOMESCO Finland
Amputation of lower leg
+∞
50.4
48
*
ZPB40
NOMESCO Finland
Polytetrafluoroethylene
260.4
49.4
50
*
PE1BT
NOMESCO Finland
Femoral artery extensive PTA
496.9
48.7
48
*
I25.1
ICD-10 Finland
Atherosclerotic heart disease
2.6
48.7
467
2323
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
5.6
47.8
149
297
S97
ICPC
Chronic ulcer skin
5.9
47.3
140
262
5585
FHL
Embolectomy or thrombectomy
+∞
47.2
45
*
PD3AT
NOMESCO Finland
Pelvic artery PTA
+∞
47.2
45
*
SPAT1148
SPAT
Treatment of chronic ulcer or burn
3.3
47.0
279
1013
I48
ICD-10 Finland
Atrial fibrillation and flutter
2.5
46.6
497
2606
PF1BT
NOMESCO Finland
Extensive PTA of arteries of knee, lower leg and ankle
+∞
45.1
43
*
PD4AD
NOMESCO Finland
CT of lower extremity arteries
453.6
44.5
44
*
PH2CD
NOMESCO Finland
Very extensive CT of inferior vena cava, pelvic veins and veins of lower extremity
159.2
44.1
46
*
TQW11
NOMESCO Finland
Vacuum treatment of wound
15.4
42.0
70
48
E11.7
ICD-10 Finland
Type 2 diabetes mellitus, with multiple complications
5.0
41.8
144
320
WX892
NOMESCO Finland
Monitored bed care
4.2
41.2
169
448
I74.2
ICD-10 Finland
Embolism and thrombosis of arteries of upper extremities
+∞
40.9
39
*
Y83
ICD-10 Finland
Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
4.4
39.1
154
392
A46
ICD-10 Finland
Erysipelas
3.0
38.8
261
1020
PEF25
NOMESCO Finland
Thrombendarterectomy of superficial femoral artery
+∞
38.7
37
*
PGH47
NOMESCO Finland
Bypass from femoral to contralateral femoral artery
+∞
38.7
37
*
C07AB07
ATC
bisoprolol; oral
2.2
37.6
697
4628
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
2.7
37.3
319
1439
N02AX02
ATC
tramadol; systemic, rectal
2.2
37.3
574
3498
PWG00
NOMESCO Finland
Reoperation on peripheral vessels for thrombosis or embolism
378.4
37.2
37
*
PWE00
NOMESCO Finland
Reoperation for deep haemorrhage in surgery of peripheral vessels and lymphatic system
72.3
37.2
42
6
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
3.6
36.8
185
583
I80.3
ICD-10 Finland
Phlebitis and thrombophlebitis of lower extremities, unspecified
5.5
35.7
111
219
GD1AA
NOMESCO Finland
Thorax X-ray examination
2.2
35.2
592
3718
SPAT1144
SPAT
Treatment of reopened or infected surgical wound
4.3
35.2
139
354
I70.0
ICD-10 Finland
Atherosclerosis of aorta
357.0
35.1
35
*
K92
ICPC
Atherosclerosis/periph vascular dis
16.7
34.9
56
35
T81.0
ICD-10 Finland
Haemorrhage and haematoma complicating a procedure, not elsewhere classified
4.7
34.6
125
291
PEN24
NOMESCO Finland
Plastic repair of deep femoral artery
+∞
34.5
33
*
PFH63
NOMESCO Finland
Bypass from femoral or popliteal artery to distal posterior tibial artery
+∞
34.5
33
*
PEF24
NOMESCO Finland
Thrombendarterectomy of deep femoral artery
+∞
34.5
33
*
M79.6
ICD-10 Finland
Pain in limb
2.3
34.3
443
2461
I50.0
ICD-10 Finland
Congestive heart failure
3.2
34.2
197
687
N02AA05
ATC
oxycodone; systemic
2.7
34.1
273
1177
NHQ30
NOMESCO Finland
Amputation of foot, transmetatarsal
+∞
33.5
32
*
PEP25
NOMESCO Finland
Percutaneous plastic repair of superficial femoral artery
+∞
33.5
32
*
PD4DG
NOMESCO Finland
Very extensive MRI examination of abdominal aortta and vasculature of lower extremities with high intensity magnet
+∞
32.4
31
*
T82.8
ICD-10 Finland
Other specified complications of cardiac and vascular prosthetic devices, implants and grafts
+∞
32.4
31
*
J01FF01
ATC
clindamycin; systemic
2.4
32.4
347
1752
J44.8
ICD-10 Finland
Other specified chronic obstructive pulmonary disease
2.9
31.9
226
902
I73.9
ICD-10 Finland
Peripheral vascular disease, unspecified
71.8
31.0
35
5
A10AC01
ATC
insulin (human); parenteral (insulins and analog. for injection, intermediate-acting)
3.5
30.6
152
471
C01AA05
ATC
digoxin; systemic
2.7
29.9
240
1031
PDQ05
NOMESCO Finland
Insertion of endovascular graft into infrarenal abdominal aorta
158.9
29.8
31
*
J18.9
ICD-10 Finland
Pneumonia, unspecified
2.1
29.7
429
2470
A49.9
ICD-10 Finland
Bacterial infection, unspecified
2.9
29.5
203
793
PDQ20
NOMESCO Finland
Insertion of endovascular graft into common iliac artery
+∞
29.3
28
*
I25.9
ICD-10 Finland
Chronic ischaemic heart disease, unspecified
2.6
29.2
246
1085
I71.2
ICD-10 Finland
Thoracic aortic aneurysm, without mention of rupture
298.7
28.9
29
*
C10AA01
ATC
simvastatin; oral
2.0
28.9
634
4313
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
2.4
28.8
280
1333
PD5BD
NOMESCO Finland
Extensive CT of aorta
10.8
28.4
55
53
206
Kela drug reimbursment
Chronic coronary artery disease and dyslipidaemia associated with chronic coronary artery disease
2.2
27.8
376
2087
PD4HE
NOMESCO Finland
Postoperative lower extremity artery ultrasound examination with Doppler method
148.4
27.7
29
*
I63.9
ICD-10 Finland
Cerebral infarction, unspecified
2.6
27.6
232
1018
WX872
NOMESCO Finland
Intensive care
4.6
27.5
100
234
TPH04
NOMESCO Finland
Cathetrisation of vein
2.3
27.2
305
1553
PFH62
NOMESCO Finland
Bypass from femoral or popliteal artery to proximal posterior tibial artery
+∞
27.2
26
*
PFU81
NOMESCO Finland
Thrombectomy or embolectomy of bypass from femoral or popliteal artery to infrapopliteal arteries
+∞
27.2
26
*
I74.4
ICD-10 Finland
Embolism and thrombosis of arteries of extremities, unspecified
+∞
27.2
26
*
A10AB05
ATC
insulin aspart; parenteral (insulins and analog. for injection, fast-acting)
3.6
26.9
130
393
XF600
NOMESCO Finland
Bloodpressure measurement
3.8
26.7
118
331
PEU81
NOMESCO Finland
Thrombectomy or embolectomy of bypass from femoral to popliteal artery
+∞
26.1
25
*
PFH59
NOMESCO Finland
Bypass from femoral or popliteal artery to distal anterior tibial artery
+∞
26.1
25
*
XF400
NOMESCO Finland
ECG with 12 standard connections
2.3
25.8
272
1340
J01MA12
ATC
levofloxacin; systemic
2.3
25.6
283
1425
B01AB04
ATC
dalteparin; parenteral
4.0
25.5
107
287
QDB99
NOMESCO Finland
Other procedure for wound of skin of lower limb
29.1
25.5
34
12
FN1AC
NOMESCO Finland
Angiography of heart and/or coronary arteries
2.2
25.4
332
1804
Y83.9
ICD-10 Finland
Surgical procedure, unspecified as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
6.4
25.3
68
112
WX882
NOMESCO Finland
High dependency care
6.0
25.1
71
125
5565
FHL
Femoropopliteal bypass surgery
+∞
25.1
24
*
PDE22
NOMESCO Finland
Thrombectomy or embolectomy of a. iliaca externa
+∞
25.1
24
*
PEN25
NOMESCO Finland
Plastic repair of superficial femoral artery
+∞
25.1
24
*
PFH66
NOMESCO Finland
Bypass from femoral or popliteal artery to dorsal artery of foot
+∞
25.1
24
*
T82.3
ICD-10 Finland
Mechanical complication of other vascular grafts
255.1
24.8
25
*
N03AX16
ATC
pregabalin; oral
2.2
24.4
299
1575
315
Kela drug reimbursment
Clopidogrel
8.8
23.7
51
60
PG9AC
NOMESCO Finland
Arteriography with X-ray not elsewhere classified
34.1
23.4
30
9
E11.9
ICD-10 Finland
Type 2 diabetes mellitus, without complications
2.0
23.2
361
2094
205
Kela drug reimbursment
Chronic hypertension
1.9
23.1
479
3102
C09AA05
ATC
ramipril; oral
2.0
23.1
387
2312
PD4CM
NOMESCO Finland
Extensive MRI examination of abdominal aorta and vasculature of lower extremities with 3 Tesla magnet
+∞
23.0
22
*
PFP99
NOMESCO Finland
Percutaneous plastic repair of artery of lower leg
+∞
23.0
22
*
I80.29
ICD-10 Finland
Phlebitis and thrombophlebitis of other deep vessels of lower extremities
5.1
22.9
74
153
ZXA05
NOMESCO Finland
Left side
2.0
22.9
352
2033
L98.4
ICD-10 Finland
Chronic ulcer of skin, not elsewhere classified
8.4
22.6
50
62
C01DA14
ATC
isosorbide mononitrate; oral
2.1
22.3
327
1849
E11.8
ICD-10 Finland
Type 2 diabetes mellitus, with unspecified complications
2.7
22.3
167
681
C01DA02
ATC
glyceryl trinitrate; oral, oral aerosol, sublingual, transdermal
1.9
22.1
420
2624
PEU99
NOMESCO Finland
Other repair after previous reconstruction of femoral artery with branches and connection to popliteal artery
+∞
21.9
21
*
PDH54
NOMESCO Finland
Bypass from aorta to bilateral femoral arteries
+∞
21.9
21
*
PDE20
NOMESCO Finland
Thrombectomy or embolectomy of common iliac artery
+∞
21.9
21
*
PFH58
NOMESCO Finland
Bypass from femoral or popliteal artery to proximal anterior tibial artery
+∞
21.9
21
*
AN1
HP
Coronary angiography
2.4
21.9
205
944
J01DB01
ATC
cefalexin; oral
1.9
21.9
892
7220
N18.9
ICD-10 Finland
Chronic kidney disease, unspecified
3.1
21.8
125
429
103
Kela drug reimbursment
Diabetes, insulin-treated
1.9
21.8
391
2387
PD1BD
NOMESCO Finland
Extensive CT of abdominal aorta and branches
18.8
21.8
33
18
PWC00
NOMESCO Finland
Reoperation for deep infection in surgery of peripheral vessels and lymphatic system
223.8
21.7
22
*
WX213
NOMESCO Finland
Lower leg blockade
31.8
21.5
28
9
JA1AE
NOMESCO Finland
Ultrasound examination of groin and abdominal wall
7.0
21.3
53
79
TK800
NOMESCO Finland
Hemodialysis
7.4
20.9
50
70
I72.3
ICD-10 Finland
Aneurysm and dissection of iliac artery
+∞
20.9
20
*
PFU99
NOMESCO Finland
Other repair after previous reconstruction of blood flow in infrapopliteal arteries
+∞
20.9
20
*
PD7ZT
NOMESCO Finland
Stent grafting of abdominal aorta
+∞
20.9
20
*
PEU85
NOMESCO Finland
Plastic repair of bypass from femoral to popliteal artery
+∞
20.9
20
*
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
2.3
20.9
221
1079
PEC23
NOMESCO Finland
Suture of common femoral artery
30.6
20.6
27
9
I82.88
ICD-10 Finland
Embolism and thrombosis of other specified veins
6.9
20.3
51
77
WX306
NOMESCO Finland
Lumbar epidural anesthesy
4.1
20.1
80
205
I25.0
ICD-10 Finland
Atherosclerotic cardiovascular disease, so described
2.9
20.0
129
479
I25.2
ICD-10 Finland
Old myocardial infarction
2.6
19.9
161
683
I50.1
ICD-10 Finland
Left ventricular failure
3.1
19.9
114
391
R4110
NOMESCO Finland
Physiotherapy
2.0
19.9
311
1794
PFG26
NOMESCO Finland
Operation for aneurysm of popliteal artery
+∞
19.8
19
*
M04AA01
ATC
allopurinol; systemic
2.2
19.8
235
1209
B01AB10
ATC
tinzaparin; parenteral
3.1
19.6
112
383
R03BB04
ATC
tiotropium bromide; inhalant
2.5
19.6
170
748
C01DA08
ATC
isosorbide dinitrate; oral, oral aerosol, sublingual, transdermal
1.9
19.5
392
2474
PD1AE
NOMESCO Finland
Ultrasound examination of abdominal aortta
46.8
19.2
23
5
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
2.2
19.0
213
1066
J44.9
ICD-10 Finland
Chronic obstructive pulmonary disease, unspecified
3.0
18.9
113
399
K55.0
ICD-10 Finland
Acute vascular disorders of intestine
+∞
18.8
18
*
I71.3
ICD-10 Finland
Abdominal aortic aneurysm, ruptured
+∞
18.8
18
*
I74.9
ICD-10 Finland
Embolism and thrombosis of unspecified artery
+∞
18.8
18
*
PFH65
NOMESCO Finland
Bypass from femoral or popliteal artery to distal peroneal artery
+∞
18.8
18
*
I70.8
ICD-10 Finland
Atherosclerosis of other arteries
71.0
18.7
21
*
L89
ICD-10 Finland
Decubitus ulcer and pressure area
6.1
18.6
51
87
J01MA02
ATC
ciprofloxacin; systemic
1.8
18.4
492
3390
J01DA01
ATC
[U] cefalexin; systemic
1.7
18.4
711
5480
TKC20
NOMESCO Finland
Catheterisation of bladder
2.6
18.3
139
566
ZXA00
NOMESCO Finland
Right side
1.9
18.3
358
2226
201
Kela drug reimbursment
Chronic cardiac insufficiency
2.6
18.1
138
563
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
2.0
18.0
275
1564
C03DA01
ATC
spironolactone; oral
2.3
17.9
187
904
I20.81
ICD-10 Finland
Other angina pectoris stenosed coronary artery
2.5
17.9
151
653
A10AE04
ATC
insulin glargine; parenteral
2.6
17.8
136
557
I72.8
ICD-10 Finland
Aneurysm and dissection of other specified arteries
+∞
17.7
17
*
PDQ22
NOMESCO Finland
Insertion of endovascular graft into a. iliaca externa
+∞
17.7
17
*
I74.8
ICD-10 Finland
Embolism and thrombosis of other arteries
+∞
17.7
17
*
FB1BD
NOMESCO Finland
Extensive CT examination of arteria pulmonalis
2.8
17.6
120
461
I69.3
ICD-10 Finland
Sequelae of cerebral infarction
2.4
17.6
156
695
PBE09
NOMESCO Finland
Thrombectomy or embolectomy of brachial artery
182.5
17.6
18
*
WX320
NOMESCO Finland
Spinalanesthesy
1.9
17.4
286
1665
I10
ICD-10 Finland
Essential (primary) hypertension
1.7
17.4
746
5882
A28
ICPC
Limited function/disability NOS
2.0
17.4
246
1352
I21.49
ICD-10 Finland
Acute subendocardial infarction unspecified coronary artery status
2.7
17.3
124
490
R06.0
ICD-10 Finland
Dyspnoea
1.9
17.0
313
1901
PG1AE
NOMESCO Finland
Ultrasound examination of artery not elsewher classified
26.0
16.9
23
9
I70
ICD-10 Finland
Atherosclerosis
26.0
16.9
23
9
QD9S1
NOMESCO Finland
Photography of skin or subcutaneous tissue in lower extremities, unspecified
19.6
16.9
25
13
PDG51
NOMESCO Finland
Bypass from aorta to iliac artery for aneurysm
+∞
16.7
16
*
PDH55
NOMESCO Finland
Bypass from iliac to femoral artery
+∞
16.7
16
*
PFP26
NOMESCO Finland
Percutaneous plastic repair of popliteal artery
+∞
16.7
16
*
PFN26
NOMESCO Finland
Plastic repair of popliteal artery
+∞
16.7
16
*
AA1AD
NOMESCO Finland
CT of head and brain
1.8
16.7
324
2001
PG1XE
NOMESCO Finland
Other ultrasound examination of blood vessel not elsewhere classified
20.4
16.4
24
12
C10AX09
ATC
ezetimibe; oral
2.5
16.4
137
589
C10AA05
ATC
atorvastatin; oral
1.7
16.3
477
3345
213
Kela drug reimbursment
Fat metabolism disorder associated with chronic coronary artery disease
2.4
16.1
151
691
N17.9
ICD-10 Finland
Acute renal failure, unspecified
3.4
16.1
78
237
I82.9
ICD-10 Finland
Embolism and thrombosis of unspecified vein
5.4
16.0
48
92
T82.7
ICD-10 Finland
Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts
33.8
15.8
20
6
T81.3
ICD-10 Finland
Disruption of operation wound, not elsewhere classified
5.4
15.7
47
90
C08CA01
ATC
amlodipine; oral
1.7
15.7
463
3246
E10.5
ICD-10 Finland
Type 1 diabetes mellitus, With peripheral circulatory complications
+∞
15.7
15
*
ZPB20
NOMESCO Finland
Vene in its own postion
+∞
15.7
15
*
XPX16
NOMESCO Finland
Ultrasound investigation of periferal vessel
+∞
15.7
15
*
ZPB96
NOMESCO Finland
Other material in vessel transplant
+∞
15.7
15
*
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.7
15.4
476
3375
L17
ICPC
Foot/toe symptom/complaint
1.9
15.3
276
1652
ZX120
NOMESCO Finland
Intravenous
2.5
15.3
127
545
I65.2
ICD-10 Finland
Occlusion and stenosis of carotid artery
4.7
15.3
52
115
K28
ICPC
Limited function/disability (K)
5.3
15.2
46
89
L28
ICPC
Limited function/disability (L)
2.0
15.2
226
1261
ZPB32
NOMESCO Finland
Covered dacron
45.6
15.1
18
*
C08CA05
ATC
nifedipine; systemic
2.5
14.9
119
498
K78
ICPC
Atrial fibrillation/flutter
2.3
14.8
140
640
NH3AA
NOMESCO Finland
Foot and toes X-ray examination
2.9
14.6
90
324
AB14W
NOMESCO Finland
NA
+∞
14.6
14
*
PFU96
NOMESCO Finland
Re-bypass from femoral or popliteal artery to lower leg of foot
+∞
14.6
14
*
44020
ICD-8 Finland
Arteriosclerosis, Of arteries of the extremities
+∞
14.6
14
*
I74.5
ICD-10 Finland
Embolism and thrombosis of iliac artery
+∞
14.6
14
*
I74.1
ICD-10 Finland
Embolism and thrombosis of other and unspecified parts of aorta
+∞
14.6
14
*
C09AA02
ATC
enalapril; systemic
1.8
14.6
301
1884
A10AE05
ATC
insulin detemir; parenteral
3.1
14.5
82
277
H02AB06
ATC
prednisolone; systemic
1.6
14.5
533
3941
SPAT1151
SPAT
Treatment of major wounds
8.0
14.4
32
41
M10.9
ICD-10 Finland
Gout, unspecified
2.6
14.3
107
434
A41.9
ICD-10 Finland
Sepsis, unspecified
3.4
14.0
69
213
A02BC02
ATC
pantoprazole; systemic
1.6
14.0
706
5646
E10.7
ICD-10 Finland
Type 1 diabetes mellitus, With multiple complications
7.2
13.9
33
47
WX602
NOMESCO Finland
Repeated or continuing anesthesia shots throug a catheter
2.7
13.9
96
370
S18
ICPC
Laceration/cut
1.6
13.7
452
3235
I71.9
ICD-10 Finland
Aortic aneurysm of unspecified site, without mention of rupture
76.0
13.6
15
*
PEG23
NOMESCO Finland
Operation for aneurysm of femoral artery
+∞
13.6
13
*
PDP20
NOMESCO Finland
Percutaneous plastic repair of common iliac artery
+∞
13.6
13
*
PET23
NOMESCO Finland
Injection of therapeutic agent into or percutaneous occlusion of femoral artery
+∞
13.6
13
*
C07AB02
ATC
metoprolol; systemic
1.7
13.5
331
2175
QDG30
NOMESCO Finland
Delayed skin closure of surgical wound in lower limb
34.4
13.5
17
5
FM1BE
NOMESCO Finland
Cardiac ultrasound examination through oesophagus
2.9
13.5
84
306
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
2.1
13.4
163
838
81
HP
Angiography of the heart and coronary arteries
2.3
13.4
126
576
N02BE01
ATC
paracetamol; systemic, rectal
1.7
13.3
940
8157
Z49.1
ICD-10 Finland
Extracorporeal dialysis
9.2
13.2
27
30
I20.01
ICD-10 Finland
Unstable angina
3.6
12.9
59
172
I48.9
ICD-10 Finland
Atrial fibrillation and atrial flutter, unspecified
2.6
12.9
95
383
Y83.2
ICD-10 Finland
Surgical operation with anastomosis, bypass or graft as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
50.5
12.9
15
*
J44.0
ICD-10 Finland
Chronic obstructive pulmonary disease with acute lower respiratory infection
2.7
12.7
90
353
A10AA02
ATC
NA
3.8
12.6
53
144
I21.41
ICD-10 Finland
Acute subendocardial infarction stenosed coronary artery
2.8
12.6
83
313
I63.4
ICD-10 Finland
Cerebral infarction due to embolism of cerebral arteries
3.0
12.6
72
247
R60.0
ICD-10 Finland
Localized oedema
2.1
12.6
148
750
PDU81
NOMESCO Finland
Thrombectomy or embolectomy in bypass from infrarenal abdominal aorta or iliac artery
+∞
12.5
12
*
I79.2*E11.5
ICD-10 Finland
Non-insulin-dependent diabetes mellitus - Diabetic peripheral angiopathy
+∞
12.5
12
*
PDG05
NOMESCO Finland
Operation on infrarenal abdominal aorta for aneurysm
+∞
12.5
12
*
PE3YT
NOMESCO Finland
Femoral and popliteal artery stentgraft therapy
+∞
12.5
12
*
PG2YT
NOMESCO Finland
Implantation of arterial endoprothesis not elsewhere classified
+∞
12.5
12
*
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
2.0
12.5
183
1012
PWA00
NOMESCO Finland
Repair of wound dehiscence in surgery of peripheral vessels and lymphatic system
131.3
12.5
13
*
SPAT1099
SPAT
Measurement of blood pressure with Doppler ultrasound device
3.8
12.4
52
141
A10BB12
ATC
glimepiride; oral
2.2
12.4
129
619
D64.9
ICD-10 Finland
Anaemia, unspecified
2.0
12.3
159
837
Z95.1
ICD-10 Finland
Presence of aortocoronary bypass graft
2.8
12.3
79
291
FN1YT
NOMESCO Finland
Percutaneous insertion of coronary artery stent
2.5
12.1
97
409
QX2XE
NOMESCO Finland
Ultrsound examination of soft tissue not elsewhere classified
4.3
12.1
44
105
M86.9
ICD-10 Finland
Osteomyelitis, unspecified
27.0
12.1
16
6
T79.6
ICD-10 Finland
Traumatic ischaemia of muscle
21.5
12.0
17
8
D68.8
ICD-10 Finland
Other specified coagulation defects
9.4
12.0
24
26
B01AC07
ATC
dipyridamole; systemic
2.3
11.9
111
503
T36
ICD-10 Finland
Poisoning by systemic antibiotics
4.2
11.9
44
107
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.6
11.7
342
2348
N07BA03
ATC
varenicline; oral
3.7
11.7
50
139
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
2.4
11.6
99
430
TPH20
NOMESCO Finland
Insertion of central venous catheter through subclavian or brachiocephalic vein
4.0
11.6
46
119
N08.39*E11.2
ICD-10 Finland
Non-insulin-dependent diabetes mellitus - Diabetic nephropathy
6.0
11.5
31
53
PGU81
NOMESCO Finland
Thrombectomy or embolectomy of extra-anatomic bypass
+∞
11.5
11
*
3013
Kela drug reimbursment
Rivaroxaban for the treatment of coronary artery disease
+∞
11.5
11
*
PG1AT
NOMESCO Finland
PTA of artery not elsewhere classified
+∞
11.5
11
*
PD3BT
NOMESCO Finland
Pelvic artery extensive PTA
+∞
11.5
11
*
XP60W
NOMESCO Finland
NA
+∞
11.5
11
*
Z89.6
ICD-10 Finland
Acquired absence of leg above knee
121.1
11.4
12
*
PD4BG
NOMESCO Finland
MRI examination of abdominal aortta and vasculature of lower extremities with high intensity magnet
121.1
11.4
12
*
4273A
ICD-9 Finland
Cardiac dysrhythmias, Atrial fibrillation and flutter
3.2
11.3
59
191
A10BA02
ATC
metformin; oral
1.6
11.3
352
2454
C09DX04
ATC
valsartan and sacubitril; oral
10.7
11.3
21
20
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.6
11.2
326
2227
N08.39*E10.2
ICD-10 Finland
Insulin-dependent diabetes mellitus - Diabetic nephropathy
25.3
11.1
15
6
AN4
HP
Balloon angioplasty and drug eluding stent
3.1
11.1
59
194
K99
ICPC
Cardiovascular disease other
3.6
11.1
50
145
FN1BC
NOMESCO Finland
Extensive angiography of hear and/or coronary arteries
2.5
11.0
89
376
127
Kela drug reimbursment
Transplant complication
7.9
10.9
24
31
A12BA01
ATC
potassium chloride; oral
2.2
10.8
107
501
A10AB01
ATC
insulin (human); parenteral (insulins and analog. for injection, fast-acting)
3.9
10.8
43
112
A11CC03
ATC
alfacalcidol; systemic
4.3
10.8
39
93
A41.0
ICD-10 Finland
Sepsis due to Staphylococcus aureus
4.3
10.8
39
93
289
Kela drug reimbursment
Combination product containing sacubitril and valsartan
8.9
10.8
22
25
215
Kela drug reimbursment
Diabetes, non-insulin-treated
1.7
10.7
271
1780
280
Kela drug reimbursment
Clopidogrel
4.6
10.7
36
80
PC1AC
NOMESCO Finland
Angiography of aorta and abdominal arteries
60.5
10.6
12
*
R50.9
ICD-10 Finland
Fever, unspecified
1.9
10.6
161
900
QBB10
NOMESCO Finland
Major dressing of wound of skin of trunk
3.5
10.6
48
140
207
Kela drug reimbursment
Chronic arrhythmias
1.7
10.5
223
1390
QDA10
NOMESCO Finland
Incision of skin of lower limb
14.3
10.5
17
12
T87.4
ICD-10 Finland
Infection of amputation stump
110.9
10.4
11
*
5579
FHL
Other measure in this category
+∞
10.4
10
*
5563
FHL
Aortopemoral bypass surgery
+∞
10.4
10
*
PFH64
NOMESCO Finland
Bypass from femoral or popliteal artery to proximal peroneal artery
+∞
10.4
10
*
NFQ48
NOMESCO Finland
Revision of exarticulation or amputation stump of hip or femur
+∞
10.4
10
*
I72.9
ICD-10 Finland
Aneurysm and dissection of unspecified site
+∞
10.4
10
*
I20.00
ICD-10 Finland
Unstable angina
2.9
10.4
64
230
FNA01
NOMESCO Finland
Anastomosis to coronary artery from internal mammary artery, one distal anastamosis
2.5
10.4
82
342
SPAT1229
SPAT
Assessment of need for aid
2.1
10.3
115
569
X59
ICD-10 Finland
Exposure to unspecified factor
1.8
10.0
175
1025
L04AD02
ATC
tacrolimus; systemic (calcineurin inhibitors)
14.7
10.0
16
11
A10AA01
ATC
NA
4.8
10.0
32
68
RS221
NOMESCO Finland
NA
6.4
9.9
25
40
L03.1
ICD-10 Finland
Cellulitis of other parts of limb
4.0
9.9
38
97
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
1.8
9.8
180
1075
I20.99
ICD-10 Finland
Angina pectoris, unspecified
2.1
9.8
115
580
B03XA02
ATC
darbepoetin alfa; parenteral
5.0
9.8
30
61
SPAT1070
SPAT
Doppler ultrasound examination of blood flow in arteries of lower extremity
4.4
9.7
34
79
L04AA06
ATC
mycophenolic acid; systemic
6.6
9.7
24
37
I80.0
ICD-10 Finland
Phlebitis and thrombophlebitis of superficial vessels of lower extremities
3.1
9.7
51
167
K94
ICPC
Phlebitis/thrombophlebitis
4.8
9.7
31
66
123
Kela drug reimbursment
Chronic disorders of vitamin D metabolism
4.0
9.7
37
94
K29
ICPC
Cardiovascular sympt/complt other
2.8
9.7
62
232
Y83.8
ICD-10 Finland
Other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
3.9
9.5
37
96
QXB99
NOMESCO Finland
Other procedure to treat skin wound, unspecified location
5.0
9.4
29
59
I70.1
ICD-10 Finland
Atherosclerosis of renal artery
100.7
9.4
10
*
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
1.5
9.4
369
2700
PWW99
NOMESCO Finland
Other reoperation on peripheral vessels or lymphatic system
+∞
9.4
9
*
PD3ZT
NOMESCO Finland
Stent grafting of pelvic artery
+∞
9.4
9
*
PX1AE
NOMESCO Finland
NA
+∞
9.4
9
*
I74.0
ICD-10 Finland
Embolism and thrombosis of abdominal aorta
+∞
9.4
9
*
PDP22
NOMESCO Finland
Percutaneous plastic repair of a. iliaca externa
+∞
9.4
9
*
PFW99
NOMESCO Finland
Other connection from femoral artery to infrapopliteal arteries or operations on popliteal artery and arteries of lower leg and foot
+∞
9.4
9
*
J01EE01
ATC
sulfamethoxazole and trimethoprim; systemic
2.4
9.4
76
323
I80.1
ICD-10 Finland
Phlebitis and thrombophlebitis of femoral vein
4.5
9.4
32
73
SPAT1253
SPAT
Initiation, adjustment, discontinuation or repetition of medication
1.6
9.3
325
2310
138
Kela drug reimbursment
Severe anaemia associated with chronic renal failure
4.3
9.3
33
78
J44.1
ICD-10 Finland
Chronic obstructive pulmonary disease with acute exacerbation, unspecified
2.8
9.2
59
220
S91.3
ICD-10 Finland
Open wound of other parts of foot
4.7
9.2
30
65
SPAT1255
SPAT
Intravenous administration of medicine
2.3
9.2
83
371
E10.2
ICD-10 Finland
Type 1 diabetes mellitus, With renal complications
13.8
9.2
15
11
4019X
ICD-9 Finland
Essential hypertension, Unspecified
2.6
9.2
66
264
G45.9
ICD-10 Finland
Transient cerebral ischaemic attack, unspecified
2.0
9.2
123
656
TPH30
NOMESCO Finland
Insertion of central venous catheter through periferal vein
5.2
9.1
27
53
E11.00
ICD-10 Finland
Non-insulin dependent diabetes diabetic hypoglycaemic coma
2.7
9.1
61
234
Z94.0
ICD-10 Finland
Kidney transplant status
9.1
9.0
18
20
JN3BD
NOMESCO Finland
Extensive abdominal CT
1.9
9.0
126
684
SPAT1149
SPAT
Suture or treatment of traumatic wound
1.8
9.0
156
911
I80.8
ICD-10 Finland
Phlebitis and thrombophlebitis of other sites
5.1
9.0
27
54
R02
ICD-10 Finland
Gangrene, not elsewhere classified
24.2
8.9
12
5
A10BB01
ATC
glibenclamide; oral
2.2
8.8
93
449
I25.5
ICD-10 Finland
Ischaemic cardiomyopathy
3.4
8.8
41
124
KA1AE
NOMESCO Finland
Kidney ultrasound examination
3.7
8.8
37
103
X57
ICD-10 Finland
Unspecified privation
3.9
8.8
34
88
I83.0
ICD-10 Finland
Varicose veins of lower extremities with ulcer
3.8
8.8
35
93
A10AD05
ATC
insulin aspart; parenteral (insulins and analog. for injection, intermediate- or long-acting comb. with fast-acting)
3.3
8.7
42
130
WX214
NOMESCO Finland
Plexus blockade at the ankle
14.1
8.7
14
10
A41.1
ICD-10 Finland
Sepsis due to other specified staphylococcus
14.1
8.7
14
10
R95
ICPC
Chron obstructive pulmonary disease
3.4
8.7
41
125
PBL09
NOMESCO Finland
Construction of arteriovenous fistula from brachial artery
50.3
8.7
10
*
PEA23
NOMESCO Finland
Exploration of femoral artery
50.3
8.7
10
*
N05CF01
ATC
zopiclone; oral
1.5
8.7
395
2975
A10AB04
ATC
insulin lispro; parenteral (insulins and analog. for injection, fast-acting)
3.9
8.6
34
90
J15.9
ICD-10 Finland
Bacterial pneumonia, unspecified
1.8
8.5
142
816
E78.01
ICD-10 Finland
Pure hypercholesterolaemia
1.6
8.5
231
1537
TFC00
NOMESCO Finland
Catheterisation of right atrium or ventricle
4.2
8.5
31
76
R55
ICD-10 Finland
Syncope and collapse
1.8
8.5
145
842
V03AE02
ATC
sevelamer; oral
20.2
8.5
12
6
D68.9
ICD-10 Finland
Coagulation defect, unspecified
20.2
8.5
12
6
I20.09
ICD-10 Finland
Unstable angina
2.1
8.4
89
432
QDG00
NOMESCO Finland
Debridement of bedsore of lower limb
90.6
8.4
9
*
PG1CG
NOMESCO Finland
Extensive MRI examination of vasculature with high intensity magnet not elsewhere classified
90.6
8.4
9
*
L14
ICPC
Leg/thigh symptom/complaint
2.2
8.4
84
398
J01MA14
ATC
moxifloxacin; systemic
2.1
8.4
99
501
XQ858
NOMESCO Finland
Oxygen partial pressure measurement
6.8
8.4
20
30
P01AB01
ATC
metronidazole; oral, rectal
1.5
8.3
357
2646
PEU91
NOMESCO Finland
Excision of bypass from femoral to popliteal artery
+∞
8.3
8
*
K55.1
ICD-10 Finland
Chronic vascular disorders of intestine
+∞
8.3
8
*
XX4FT
NOMESCO Finland
Exchange to other catheter with radiological guidance
+∞
8.3
8
*
PF1YT
NOMESCO Finland
Stenting of tibial or ankle arteries
+∞
8.3
8
*
G54.6
ICD-10 Finland
Phantom limb syndrome with pain
+∞
8.3
8
*
PFH60
NOMESCO Finland
Bypass from femoral or popliteal artery to tibioperoneal trunk
+∞
8.3
8
*
PGH44
NOMESCO Finland
Bypass from axillary to bilateral femoral arteries
+∞
8.3
8
*
TPH90
NOMESCO Finland
Removal of fixed intravenous catheter
6.3
8.3
21
34
25000
ICD-8 Finland
Diabetes mellitus, Sine complicatione
3.2
8.3
41
130
H02AB07
ATC
prednisone; oral
1.8
8.3
160
966
T90
ICPC
Diabetes non-insulin dependent
1.6
8.3
252
1727
WX002
NOMESCO Finland
Sedation and analgesia
1.6
8.2
211
1386
R53
ICD-10 Finland
Malaise and fatigue
1.6
8.2
232
1561
A04.7
ICD-10 Finland
Enterocolitis due to Clostridium difficile
3.2
8.2
41
131
Z76.9
ICD-10 Finland
Person encountering health services in unspecified circumstances
2.2
8.2
79
367
R26.2
ICD-10 Finland
Difficulty in walking, not elsewhere classified
5.7
8.1
22
39
N18.8
ICD-10 Finland
Other chronic renal failure
3.2
8.1
41
132
381
Kela drug reimbursment
Combination product containing sacubitril and valsartan
8.2
8.1
17
21
I20.90
ICD-10 Finland
Angina pectoris, unspecified
2.3
8.1
71
316
A12AA04
ATC
calcium carbonate; oral
4.9
8.1
25
52
N28.0
ICD-10 Finland
Ischaemia and infarction of kidney
33.6
8.1
10
*
FN1AT
NOMESCO Finland
Endovascular dilatation of coronary arteries (PTCA)
2.2
8.1
79
371
PAF14
NOMESCO Finland
Thrombendarterectomy of internal carotid artery
3.9
8.0
31
81
AN2
HP
Balloon angioplasty, including several vessels
3.0
7.9
43
146
JN3AA
NOMESCO Finland
Abdominal X-ray examination without contrast
2.3
7.8
67
296
L02.4
ICD-10 Finland
Cutaneous abscess, furuncle and carbuncle of limb
3.3
7.8
37
114
FN1BT
NOMESCO Finland
Extensive endovascular dilatation of coronary (PTCA) arteries
3.2
7.8
38
120
WX404
NOMESCO Finland
Intravenous generell anesthesy
1.6
7.7
188
1217
B01AF02
ATC
apixaban; oral
1.8
7.7
133
776
I80.9
ICD-10 Finland
Phlebitis and thrombophlebitis of unspecified site
4.4
7.7
26
60
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
1.6
7.6
190
1235
A41.5
ICD-10 Finland
Sepsis due to other Gram-negative organisms
2.7
7.6
52
201
TPX10
NOMESCO Finland
Implantation of vascular injection port
3.3
7.6
36
111
SPAT1083
SPAT
Initiation and monitoring of IV fluid therapy
2.5
7.6
56
228
SPAT1222
SPAT
Counselling/guidance promoting independent living
1.6
7.6
188
1220
PC1BC
NOMESCO Finland
Extensive angiography of aorta and abdominal arteries
25.2
7.6
10
*
A07AA09
ATC
vancomycin; oral
5.2
7.6
22
43
J01CF05
ATC
flucloxacillin; systemic
3.0
7.6
43
148
G72.8
ICD-10 Finland
Other specified myopathies
3.7
7.5
31
86
XF603
NOMESCO Finland
Direct intraarterial blood pressure measurement
2.8
7.5
45
164
N02AC04
ATC
dextropropoxyphene; oral
2.2
7.4
70
324
379
Kela drug reimbursment
Apixaban, dabigatran, edoxaban and rivaroxaban for the long-term prevention of recurrent deep veinthrombosis and pulmonary embolism
3.5
7.4
33
97
XCK10
NOMESCO Finland
Photography of fundus of eye
1.8
7.4
122
699
WX000
NOMESCO Finland
Monitoring vital functions without anesthesy
2.7
7.4
49
189
N02AJ06
ATC
codeine and paracetamol; systemic
1.5
7.4
321
2380
EBA15
NOMESCO Finland
Extraction of large number of teeth
2.8
7.4
47
175
JN4BD
NOMESCO Finland
Extensive body CT
1.8
7.4
132
779
E10.9
ICD-10 Finland
Type 1 diabetes mellitus, Without complications
3.0
7.3
39
131
B01AC30
ATC
platelet aggregation inhibitors excl. heparin - combinations
1.9
7.3
103
558
S78.1
ICD-10 Finland
Traumatic amputation at level between hip and knee
+∞
7.3
7
*
296
Kela drug reimbursment
Rivaroxaban for the treatment of coronary heart disease
+∞
7.3
7
*
PEQ23
NOMESCO Finland
Insertion of endovascular graft into femoral artery
+∞
7.3
7
*
PG1DM
NOMESCO Finland
Very extensive MRI examination of vasculature not elsewhere classified with 3 Tesla magnet
+∞
7.3
7
*
XP601
NOMESCO Finland
NA
+∞
7.3
7
*
NGQ10
NOMESCO Finland
Exarticulation of knee
+∞
7.3
7
*
PGU99
NOMESCO Finland
Other repair of extra-anatomic bypass
+∞
7.3
7
*
NGQ48
NOMESCO Finland
Revision of exarticulation or amputation stump of knee or lower leg
+∞
7.3
7
*
PDG54
NOMESCO Finland
Bypass from aorta to femoral artery for aneurysm
+∞
7.3
7
*
JN3AD
NOMESCO Finland
Abdominal CT examination
2.0
7.3
85
432
SPAT1254
SPAT
Administration of medicine
1.6
7.2
177
1145
E87.5
ICD-10 Finland
Hyperkalaemia
3.6
7.2
30
84
I50
ICD-10 Finland
Heart failure
2.5
7.2
53
216
C02AC05
ATC
moxonidine; oral
2.4
7.1
56
235
L84
ICD-10 Finland
Corns and callosities
3.1
7.1
37
123
I26.9
ICD-10 Finland
Pulmonary embolism without mention of acute cor pulmonale
2.1
7.1
81
407
QDE35
NOMESCO Finland
Repair of skin defect in lower limb after surgery or injury
12.1
7.1
12
10
PD5AD
NOMESCO Finland
CT of aorta
4.3
7.0
24
56
E11.2
ICD-10 Finland
Type 2 diabetes mellitus, with renal complications
2.6
7.0
47
183
WX402
NOMESCO Finland
General anaesthesia
1.7
7.0
139
848
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
1.6
7.0
194
1298
I11.9
ICD-10 Finland
Hypertensive heart disease without (congestive) heart failure
2.2
6.9
66
306
R11
ICD-10 Finland
Nausea and vomiting
2.0
6.9
86
445
R4180
NOMESCO Finland
Podiatric therapy
5.9
6.9
18
31
C02EA02
ATC
NA
2.0
6.9
80
406
QX3HE
NOMESCO Finland
Ultrsound examination of lesion close to skin
4.4
6.9
23
53
RS220
NOMESCO Finland
NA
4.8
6.9
21
44
D50.9
ICD-10 Finland
Iron deficiency anaemia, unspecified
1.9
6.8
92
494
N03AX12
ATC
gabapentin; oral
1.7
6.8
144
893
PD5CD
NOMESCO Finland
Very extensive CT angiography of aorta
8.3
6.8
14
17
I15.1
ICD-10 Finland
Hypertension secondary to other renal disorders
6.7
6.8
16
24
Y88.3
ICD-10 Finland
Sequelae of surgical and medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
2.9
6.8
39
137
H3603, E113
ICD-10 Finland
NA
6.1
6.8
17
28
RJ414
NOMESCO Finland
NA
40.3
6.8
8
*
PD5CG
NOMESCO Finland
Extensive MRI examination of thoracal and abdominal aortta with high intensity magnet
40.3
6.8
8
*
SPAT1217
SPAT
Assessment of need for services (elderly/care support)
1.8
6.8
106
600
XF612
NOMESCO Finland
Measurement of central venous pressure
16.8
6.7
10
6
C10AA04
ATC
fluvastatin; oral
1.8
6.7
120
709
Z72.0
ICD-10 Finland
Tobacco use
3.8
6.7
26
69
V03AE01
ATC
polystyrene sulfonate; oral
4.5
6.7
22
50
N19
ICD-10 Finland
Unspecified kidney failure
2.4
6.7
51
214
Z49.0
ICD-10 Finland
Preparatory care for dialysis
6.5
6.6
16
25
190
Kela drug reimbursment
Lanthanum carbonate, sevelamer and sucroferric oxyhydroxide
7.9
6.6
14
18
SPAT1262
SPAT
Handing over of treatment supplies
1.6
6.6
201
1374
SPAT1156
SPAT
Guidance concerning treatment of rash and skin
1.6
6.6
154
984
A98
ICPC
Health maint/preventive medicine
0.7
6.6
778
8640
WW500
NOMESCO Finland
Blood transfusion
2.5
6.6
50
209
QWA00
NOMESCO Finland
Repair of wound dehiscence in surgery of skin
10.1
6.5
12
12
N05CD07
ATC
temazepam; oral
1.6
6.5
183
1228
N17.8
ICD-10 Finland
Other acute renal failure
4.0
6.5
24
61
WX212
NOMESCO Finland
Femoral plexus blockade
3.2
6.4
31
98
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
1.6
6.4
172
1139
351
Kela drug reimbursment
Apixaban, dabigatran, edoxaban and rivaroxaban for the treatment of atrial fibrillation
1.6
6.4
163
1065
FNC30
NOMESCO Finland
Aorto-coronary venous bypass with three distal anastomoses
3.3
6.4
30
93
PD1CD
NOMESCO Finland
Very extensive CT of abdominal aorta and branches
14.4
6.4
10
7
R03AK06
ATC
salmeterol and fluticasone; inhalant
1.6
6.4
152
974
T81.9
ICD-10 Finland
Unspecified complication of procedure
3.8
6.4
25
67
N02AB03
ATC
fentanyl; nasal, sublingual, transdermal
2.1
6.4
69
339
KAS10
NOMESCO Finland
Allogenic transplantation of kidney from cadaver donor
8.2
6.3
13
16
C08CA02
ATC
felodipine; oral
1.7
6.3
128
785
PB1DE
NOMESCO Finland
Upper extremity arteries ultrasound examination with Doppler method
11.1
6.3
11
10
T81.7
ICD-10 Finland
Vascular complications following a procedure, not elsewhere classified
9.3
6.3
12
13
J45.9
ICD-10 Finland
Asthma, unspecified
1.6
6.3
179
1204
5568
FHL
Femorofemoral bypass surgery
+∞
6.3
6
*
I702, L97
ICD-10 Finland
NA
+∞
6.3
6
*
I77.8
ICD-10 Finland
Other specified disorders of arteries and arterioles
+∞
6.3
6
*
5566
FHL
Femorotibial bypass surgery
+∞
6.3
6
*
T87.6
ICD-10 Finland
Other and unspecified complications of amputation stump
+∞
6.3
6
*
PEW99
NOMESCO Finland
Other operation on femoral artery with branches and connection to popliteal artery
+∞
6.3
6
*
PDU84
NOMESCO Finland
Plastic repair of bypass from infrarenal abdominal aorta or iliac artery
+∞
6.3
6
*
AB18W
NOMESCO Finland
NA
+∞
6.3
6
*
PFH67
NOMESCO Finland
Bypass from femoral or popliteal artery to posterior tibial artery in foot
+∞
6.3
6
*
PG5AC
NOMESCO Finland
Contrast examination of injection gate to artery or vein
+∞
6.3
6
*
PGU91
NOMESCO Finland
Excision of extra-anatomic bypass
+∞
6.3
6
*
5562
FHL
Reconstruction of the aortoil cabbage area
+∞
6.3
6
*
I51.3
ICD-10 Finland
Intracardiac thrombosis, not elsewhere classified
+∞
6.3
6
*
I79.2*E10.5
ICD-10 Finland
Insulin-dependent diabetes mellitus - Diabetic peripheral angiopathy
+∞
6.3
6
*
I77.9
ICD-10 Finland
Disorder of arteries and arterioles, unspecified
+∞
6.3
6
*
I71.00
ICD-10 Finland
Dissecting aneurysm of aorta (ruptured) [any part]
+∞
6.3
6
*
F10.1
ICD-10 Finland
Mental and behavioural disorders due to use of alcohol, Harmful use
2.2
6.2
61
287
I42.0
ICD-10 Finland
Dilated cardiomyopathy
2.7
6.2
40
150
J96.0
ICD-10 Finland
Acute respiratory failure
4.0
6.2
23
59
XF655
NOMESCO Finland
Measurement of heart muscle perfusion with exercise
2.7
6.2
40
152
I35.0
ICD-10 Finland
Aortic (valve) stenosis
1.9
6.2
88
481
L04AA01
ATC
[U] ciclosporin; systemic
4.5
6.2
20
45
S91.1
ICD-10 Finland
Open wound of toe(s) without damage to nail
4.5
6.2
20
45
C02CA01
ATC
prazosin; oral
3.0
6.2
33
113
R03AL01
ATC
fenoterol and ipratropium bromide; inhalant
3.0
6.2
33
113
H3603, E103
ICD-10 Finland
NA
7.7
6.1
13
17
WX702
NOMESCO Finland
Supraglottic ventilation device
2.4
6.1
48
205
WZC10
NOMESCO Finland
Extensive specialist consultion with written report
2.4
6.1
47
198
TFP20
NOMESCO Finland
Cardiodefibrillation
1.8
6.1
93
521
R52.0
ICD-10 Finland
Acute pain
3.1
6.1
30
97
C09BA02
ATC
enalapril and diuretics; systemic
1.8
6.1
104
607
61
HP
Catheterization and pressure measurement of the left side of the heart
2.9
6.1
35
124
1CX08
NOMESCO Finland
NA
8.6
6.1
12
14
I26.0
ICD-10 Finland
Pulmonary embolism with mention of acute cor pulmonale
3.0
6.0
32
109
AA1
HP
Conventional CABG
3.0
6.0
32
109
Z95.8
ICD-10 Finland
Presence of other cardiac and vascular implants and grafts
10.1
6.0
11
11
QBB05
NOMESCO Finland
Revision of wound of skin of trunk
5.2
6.0
17
33

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
329
303
14.10
320.72
5.2
1.8
1145.1
541.0
ug/l
0.67
317
280
328
1065
3.76
85.43
2.9
1.5
—
—
—
0
0
387
1548
3.12
70.69
5.3
1.9
33.0
29.8
s
8.16
372
1499
355
1363
3.19
69.44
3.3
1.9
—
—
—
0
0
81
88
9.73
68.03
1.3
1.2
—
—
—
0
0
140
287
5.33
65.53
4.0
1.7
24.4
21.5
s
1.61
114
257
412
1876
2.73
57.63
3.1
1.6
2.0
1.4
mg/l
3.20
351
1454
73
88
8.72
56.51
1.3
1.2
3.5
3.7
u/ml
0.06
27
43
257
914
3.25
56.16
10.5
5.9
12.1
11.1
mmol/l
1.03
240
851
568
3141
2.41
51.58
6.9
4.1
—
—
—
0
0
724
4462
2.37
51.11
19.8
10.7
1.5
1.4
inr
3.49
203
1241
303
1303
2.72
46.22
12.2
5.9
104.2
104.2
mmol/l
0.04
298
1271
300
1346
2.59
41.58
7.7
5.0
1.1
1.0
mmol/l
3.58
274
1225
284
1274
2.56
39.16
11.1
6.0
0.5
1.1
mmol/l
1.67
221
984
283
1270
2.56
38.98
11.1
6.0
11.9
11.8
kpa
0.09
266
1201
283
1270
2.56
38.98
11.1
6.0
5.1
5.1
kpa
0.04
268
1199
330
1609
2.40
37.85
37.8
28.0
1.9
1.5
inr
3.14
33
218
301
1411
2.46
37.64
3.8
2.4
18.7
22.5
%
5.17
261
1191
312
1499
2.41
36.88
3.6
2.3
2.2
2.3
g/l
0.92
290
1364
525
3140
2.11
36.17
3.1
2.2
438.4
232.1
u/l
2.33
493
2929
255
1131
2.55
35.74
11.7
6.3
95.8
95.4
%
0.58
244
1087
507
3073
2.05
32.99
4.3
2.5
—
—
—
0
0
232
1020
2.54
32.93
12.4
6.7
113.9
121.5
g/l
6.41
223
979
321
1635
2.27
32.71
4.4
3.0
0.8
0.8
mmol/l
1.86
298
1522
321
1644
2.26
32.22
3.6
2.4
10.1
12.6
umol/l
8.91
294
1498
654
4416
1.95
30.55
7.2
4.1
—
—
—
0
0
224
1016
2.45
29.53
6.6
3.5
5.9
5.8
kpa
1.07
213
980
222
1016
2.42
28.64
6.7
3.5
1.5
2.1
mmol/l
1.18
175
786
393
2330
1.97
26.00
4.2
2.3
—
—
—
0
0
194
886
2.39
24.96
12.5
7.3
—
—
—
0
0
39
60
6.66
24.35
2.5
2.2
—
—
—
0
0
195
919
2.31
23.26
10.4
6.2
1.5
1.4
mmol/l
0.32
186
884
393
2422
1.88
22.63
8.1
3.7
79.0
84.0
%
2.62
380
2363
170
766
2.40
22.44
9.0
3.8
—
—
—
0
0
137
560
2.61
22.24
14.0
8.3
—
—
—
0
0
435
2783
1.84
22.15
2.9
2.1
4.0
3.0
mg/l
6.80
374
2325
125
490
2.71
22.05
6.7
3.8
23.2
24.2
mmol/l
2.68
112
441
123
479
2.73
21.98
2.2
1.7
1.9
3.0
ug/l
0.46
105
408
630
4505
1.76
21.92
8.1
4.4
31.6
34.8
g/l
27.53
591
4133
156
696
2.41
21.00
13.1
5.7
24.1
24.4
mmol/l
0.54
144
650
205
1043
2.14
20.12
3.2
2.5
11.2
6.4
ug/l
1.48
176
883
177
849
2.25
20.12
5.7
2.9
4.2
4.5
kpa
1.16
164
815
246
1343
2.02
19.98
2.2
2.4
2.0
1.8
%
1.97
215
1170
134
573
2.49
19.76
11.9
8.0
23.6
24.5
mmol/l
2.15
122
535
510
3539
1.72
18.97
4.6
3.0
3930.3
1670.8
ng/l
4.90
456
3049
74
245
3.14
17.70
4.7
3.8
—
—
—
0
0
120
517
2.45
17.38
2.1
1.9
1.7
1.5
g/l
2.01
104
443
18
18
10.12
15.82
1.2
1.3
—
—
—
0
0
452
3176
1.64
15.24
6.8
5.4
—
—
—
0
0
434
3024
1.65
15.10
3.4
2.5
54.7
57.3
u/l
0.66
402
2742
668
5184
1.58
14.71
8.2
6.1
12.9
12.6
umol/l
0.24
630
4880
332
2173
1.70
14.60
3.8
2.9
536.1
560.6
mosm/kgh2o
1.30
287
1859
102
443
2.41
14.50
9.8
4.3
0.9
0.9
%
0.57
93
416
749
5982
1.58
14.46
9.7
4.6
7.2
6.8
mmol/l
3.24
726
5612
666
5182
1.57
14.38
12.1
6.5
1.2
1.2
mmol/l
13.63
571
4314
102
450
2.37
14.00
9.7
4.3
1.9
1.6
%
1.38
93
422
616
4743
1.56
13.70
11.9
5.7
1.2
1.2
mmol/l
10.98
576
4237
427
3069
1.58
12.60
6.6
3.9
7.4
7.4
ph
0.39
89
595
165
919
1.91
12.33
2.0
2.2
0.2
0.2
g/l
3.08
152
848
62
234
2.73
11.78
12.1
5.6
105.7
104.9
mmol/l
0.86
53
209
62
234
2.73
11.78
12.1
5.6
12.0
11.2
mmol/l
0.93
53
209
310
2102
1.62
11.54
6.8
4.0
799.1
361.4
ng/l
0.39
282
1794
183
1075
1.81
11.54
2.9
2.7
11.4
9.6
umol/l
0.30
157
934
506
3837
1.51
11.46
4.1
2.7
164.0
153.2
ug/l
0.39
467
3435
332
2293
1.60
11.44
7.8
6.5
—
—
—
0
0
57
211
2.78
11.25
4.5
3.1
—
—
—
0
0
449
3331
1.52
11.22
4.0
3.5
—
—
—
0
0
15
19
7.97
11.01
1.3
1.0
—
—
—
0
0
64
255
2.58
10.95
5.7
4.5
2.7
2.6
mmol/l
0.17
40
174
578
4537
1.48
10.90
7.0
5.3
0.0
0.0
e9/l
0.57
507
3852
176
1042
1.79
10.79
5.5
3.0
347.9
243.7
ng/l
1.94
167
943
575
4516
1.48
10.78
7.0
5.3
0.7
0.6
e9/l
2.29
503
3824
14
17
8.31
10.62
1.8
1.1
—
—
—
0
0
535
4160
1.48
10.45
7.4
5.5
0.6
0.6
%
0.72
506
3839
584
4630
1.47
10.28
7.2
5.4
1.7
1.9
e9/l
2.16
517
4007
547
4287
1.47
10.19
7.7
5.8
8.7
9.0
%
1.64
514
3972
557
4384
1.47
10.14
7.7
5.7
22.7
26.1
%
9.42
526
4033
589
4689
1.46
10.09
7.5
5.5
0.2
0.2
e9/l
0.45
524
4048
169
1009
1.77
10.05
2.5
2.5
73.1
68.1
e9/l
0.85
125
787
655
5327
1.45
9.99
10.2
8.6
5.1
4.3
e9/l
8.61
583
4594
543
4273
1.46
9.80
7.4
5.5
2.7
2.8
%
0.78
512
3940
137
775
1.86
9.72
4.9
3.7
138.0
92.0
ng/l
1.85
115
657
74
337
2.27
9.48
11.5
5.1
1.2
1.3
mmol/l
1.60
64
293
90
445
2.10
9.40
10.0
3.8
—
—
—
0
0
19
37
5.19
9.36
7.6
1.4
59.2
68.1
mg/l
0.29
13
29
542
4290
1.44
9.36
7.3
5.5
62.4
58.4
%
11.22
511
3978
132
749
1.85
9.27
4.5
4.2
5.2
5.2
kpa
0.04
121
684
159
956
1.75
9.21
2.0
2.9
62.7
66.1
g/l
5.45
139
863
322
2308
1.52
9.15
3.4
2.7
5.6
4.5
e6/l
0.90
290
2044
56
230
2.50
9.04
3.8
2.5
14.7
15.8
%
0.89
32
107
394
2959
1.47
8.86
4.5
3.3
0.8
0.5
e6/l
1.06
333
2286
13
18
7.28
8.85
4.4
4.9
—
—
—
0
0
129
738
1.83
8.83
4.4
4.2
7.4
7.4
ph
0.45
25
83
423
3238
1.45
8.56
4.5
3.4
80.3
99.1
e6/l
0.23
362
2548
70
326
2.21
8.52
3.0
3.1
0.9
0.8
nmol/l
0.72
54
255
67
310
2.22
8.30
6.0
4.1
7.4
7.4
ph
0.67
62
249
378
2852
1.45
8.19
4.4
3.3
—
—
—
0
0
342
2550
1.46
7.84
3.1
2.8
1414.6
8213.5
umol/l
4.73
304
2130
37
135
2.79
7.58
1.5
1.6
—
—
—
0
0
523
4235
1.39
7.45
6.8
3.9
57.1
67.2
ng/l
0.24
438
3244
21
54
3.93
7.44
4.5
3.1
—
—
—
0
0
36
131
2.80
7.41
1.4
1.4
—
—
—
0
0
152
959
1.66
7.36
1.9
1.6
—
—
—
0
0
12
19
6.36
7.24
1.8
1.0
—
—
—
0
0
62
296
2.15
7.14
2.8
3.8
—
—
—
0
0
51
225
2.32
7.10
3.5
2.2
124.6
127.8
g/l
0.38
39
163
457
3642
1.39
7.08
5.1
3.9
76.2
126.5
e6/l
1.04
370
2703
77
407
1.95
6.75
2.9
3.2
194.3
10045.5
u/ml
0.82
66
343
312
2360
1.42
6.46
1.9
1.8
1248.2
1174.0
nmol/l
0.60
247
1752
64
322
2.04
6.45
5.2
3.7
—
—
—
0
0
185
2613
0.66
6.35
2.5
3.3
0.8
0.8
ug/l
0.11
132
1858
119
735
1.68
6.26
1.8
1.5
—
—
—
0
0
137
879
1.62
6.21
2.7
2.3
31.0
33.8
u/l
0.45
124
741
811
8996
0.75
6.12
5.3
4.9
6.4
6.1
mmol/l
5.62
733
7972
73
399
1.88
5.82
2.7
3.7
42.4
48.0
mg/l
0.24
56
332
52
252
2.11
5.81
2.3
2.4
121.3
92.2
ug/min
0.23
30
147
243
1788
1.44
5.81
3.7
2.9
1.3
1.1
e6/l
0.35
157
1041
73
400
1.87
5.78
2.7
3.6
53.2
67.9
mg/l
0.34
54
330
230
1679
1.45
5.73
3.9
3.1
3.0
1.9
e6/l
0.77
141
941
127
821
1.60
5.59
1.7
1.5
—
—
—
0
0
28
107
2.65
5.33
4.9
3.4
—
—
—
0
0
19
59
3.25
5.17
1.0
1.2
—
—
—
0
0
80
476
1.72
4.87
1.4
1.4
—
—
—
0
0
10
20
5.03
4.77
1.7
1.9
—
—
—
0
0
44
219
2.04
4.64
6.1
2.8
—
—
—
0
0
479
4035
1.29
4.63
17.0
9.8
0.0
0.0
e9/l
0.53
392
3254
161
1150
1.45
4.48
3.5
4.0
64.6
23.5
ug/l
0.42
130
977
151
1072
1.46
4.34
1.6
1.4
—
—
—
0
0
743
6652
1.26
4.24
6.4
4.9
1138.4
1565.0
e6/l
0.14
12
111
71
426
1.70
4.23
3.4
3.2
4.2
4.4
pmol/l
1.17
63
368
119
811
1.51
4.19
2.4
2.1
385.7
375.0
nmol/l
0.18
104
737
838
9090
0.79
4.18
5.7
5.1
2.3
2.6
mmol/l
19.98
782
8147
29
128
2.29
4.14
6.7
7.3
6.8
7.6
mmol/l
0.86
23
106
814
8847
0.79
4.04
5.0
4.5
4.1
4.4
mmol/l
18.06
762
7983
50
275
1.85
4.00
1.5
1.4
234.5
278.0
ug/g
0.72
33
172
512
4411
1.26
3.98
2.3
2.1
91.7
92.0
pmol/l
0.04
295
2308
36
177
2.06
3.96
4.1
3.2
61.4
59.1
%
0.44
36
177
804
8738
0.80
3.91
4.9
4.5
1.3
1.4
mmol/l
15.76
748
7814
30
138
2.20
3.91
1.4
1.4
20523.7
43182.6
e6/l
0.52
19
85
35
172
2.06
3.87
3.4
2.9
5.0
4.6
e9/l
0.33
35
172
323
2647
1.29
3.74
1.9
1.6
17.1
20.5
nmol/l
3.90
285
2218
416
3522
1.26
3.70
3.6
3.3
2.3
2.3
mmol/l
2.77
354
3003
114
792
1.48
3.68
4.1
3.9
0.9
0.9
%
0.14
44
260
26
116
2.26
3.65
1.5
1.5
—
—
—
0
0
43
233
1.87
3.63
1.3
1.2
—
—
—
0
0
116
817
1.46
3.51
2.1
2.7
—
—
—
0
0
17
63
2.72
3.49
1.0
1.2
—
—
—
0
0
18
70
2.59
3.38
1.2
1.1
440.0
185.0
titre
—
7
12
17
65
2.63
3.30
2.0
2.4
—
—
—
0
0
6
7
8.60
3.26
1.0
1.0
—
—
—
0
0
212
2647
0.76
3.25
3.6
3.1
—
—
—
0
0
36
192
1.90
3.21
1.5
1.3
55.5
62.7
mmol/l
0.55
27
162
46
267
1.75
3.15
1.4
1.2
—
—
—
0
0
15
56
2.70
3.06
1.9
1.3
—
—
—
0
0
953
10073
0.81
3.04
51.6
23.8
4.2
4.4
e12/l
18.72
925
9690
953
10073
0.81
3.04
51.3
23.7
30.2
30.5
pg
3.86
934
9841
953
10071
0.81
3.02
51.4
23.7
91.9
91.7
fl
0.41
933
9841
953
10070
0.81
3.01
51.6
23.8
248.0
238.3
e9/l
3.24
931
9725
94
657
1.46
2.99
3.2
2.6
10.4
10.9
g/l
0.38
89
592
19
81
2.36
2.99
1.3
1.2
—
—
nmol/l
—
0
0
954
10076
0.81
2.97
52.0
23.9
125.7
133.5
g/l
35.25
932
9847
954
10076
0.81
2.97
51.6
23.8
7.9
6.9
e9/l
25.44
927
9691
99
703
1.44
2.90
3.9
3.8
0.6
0.6
%
0.03
29
184
374
3203
1.23
2.90
4.5
3.9
19.8
8.8
mg/mmol
2.54
255
2042
15
58
2.60
2.87
1.0
1.6
—
—
—
0
0
81
555
1.49
2.85
4.4
4.3
—
—
—
0
0
32
172
1.88
2.82
2.7
2.4
—
—
—
0
0
786
8443
0.83
2.81
4.5
4.0
1.4
1.3
mmol/l
4.58
727
7472
29
151
1.94
2.81
1.4
1.4
899.8
1507.1
e6/l
1.44
19
112
34
187
1.84
2.80
3.5
3.7
0.9
1.4
%
0.43
28
142
33
180
1.85
2.79
1.2
1.3
33.4
46.1
u/l
0.39
27
159
28
145
1.95
2.76
1.5
1.4
—
—
—
0
0
416
3620
1.22
2.74
4.5
3.7
—
6.1
—
0
5
733
6726
1.20
2.73
5.9
4.5
—
—
—
0
0
41
243
1.71
2.65
1.7
1.6
26647.2
19064.9
e6/l
0.25
30
176
805
7465
1.20
2.62
10.9
7.4
88.4
80.1
u/l
3.41
761
6921
23
113
2.05
2.62
1.1
1.5
0.7
0.8
g/l
0.31
11
89
96
692
1.42
2.62
4.2
4.0
0.0
0.6
%
0.68
31
200
29
156
1.88
2.57
8.9
2.5
—
—
—
0
0
44
269
1.66
2.55
7.3
3.0
2.1
1.7
mmol/l
1.38
44
263
33
186
1.79
2.54
1.5
1.5
—
—
—
0
0
101
740
1.39
2.52
4.2
4.0
0.1
0.1
%
0.74
39
236
20
95
2.12
2.49
1.5
1.2
0.6
0.6
nmol/l
0.19
20
90
75
522
1.46
2.48
1.9
1.8
1.2
1.7
g/l
1.13
69
471
131
1004
1.34
2.47
1.3
1.3
515.2
465.7
titre
0.09
25
216
116
873
1.36
2.46
9.4
3.6
1.2
1.2
mmol/l
1.24
108
757
400
4529
0.83
2.45
4.1
5.4
2.1
4.1
ug/l
1.50
347
4002
6
175
0.34
2.41
1.5
1.3
—
—
—
0
0
68
467
1.48
2.41
4.3
4.6
24.5
24.9
mmol/l
0.54
58
431
29
160
1.83
2.40
3.8
2.3
—
—
—
0
0
5
8
6.26
2.37
1.0
1.0
—
—
—
0
0
14
58
2.43
2.37
3.9
1.4
—
—
—
0
0
12
276
0.43
2.34
1.5
1.4
—
—
—
0
0
250
2096
1.24
2.33
3.2
3.1
2.5
2.5
mmol/l
3.42
207
1823
271
2292
1.23
2.33
1.4
1.3
—
—
—
0
0
350
3038
1.21
2.32
3.6
3.2
406.2
274.3
mg/l
0.25
239
1962
22
407
0.53
2.31
1.4
1.4
—
—
—
0
0
923
9702
0.84
2.27
15.6
10.7
25.3
24.9
u/l
0.30
886
9251
20
99
2.03
2.26
1.4
1.7
—
—
—
0
0
20
99
2.03
2.26
1.4
1.7
—
—
—
0
0
20
99
2.03
2.26
1.4
1.7
—
—
—
0
0
20
99
2.03
2.26
1.4
1.7
—
—
—
0
0
219
1816
1.25
2.26
5.6
4.3
—
—
—
0
0
32
186
1.74
2.25
1.2
1.2
—
—
—
0
0
20
100
2.01
2.21
2.1
2.1
1.2
2.1
u/field
—
6
31
41
257
1.61
2.19
7.8
3.1
9.4
7.7
mmol/l
2.04
41
252
354
3091
1.20
2.19
3.7
3.1
6.7
7.5
mmol/l
3.84
299
2528
43
273
1.59
2.19
2.0
1.6
—
—
—
0
0
27
151
1.80
2.16
1.7
1.4
—
—
—
0
0
97
731
1.35
2.08
1.4
1.5
—
—
—
0
0
23
124
1.87
2.07
1.6
2.4
—
—
—
0
0
15
69
2.19
2.04
1.1
1.2
0.4
0.4
g/l
—
8
50
15
69
2.19
2.04
1.1
1.2
5.2
6.6
g/l
—
8
49
15
69
2.19
2.04
1.1
1.2
2.4
2.9
g/l
—
8
50
24
132
1.83
2.04
1.2
1.2
—
—
—
0
0
11
44
2.51
2.01
2.5
2.4
932.4
1374.0
u/ml
0.50
11
44
5
11
4.56
1.94
1.2
1.1
—
—
—
0
0
66
473
1.42
1.92
1.6
1.3
—
—
—
0
0
15
71
2.12
1.92
1.2
1.2
—
—
—
0
0
109
849
1.31
1.89
5.4
4.1
—
—
—
0
0
7
22
3.19
1.88
6.3
6.7
—
—
—
0
0
7
22
3.19
1.88
1.6
1.5
—
—
—
0
0
13
59
2.21
1.84
1.2
1.7
—
—
—
0
0
52
361
1.46
1.81
1.4
2.6
33.9
37.1
g/l
3.05
44
309
107
837
1.30
1.80
1.7
1.4
—
—
—
0
0
24
138
1.75
1.80
1.7
2.3
—
—
—
0
0
511
4666
1.15
1.77
4.9
3.9
0.0
0.0
estimate
0.00
111
889
12
245
0.48
1.76
1.2
1.1
—
—
—
0
0
18
95
1.91
1.75
1.8
1.5
—
—
—
0
0
27
163
1.67
1.72
1.4
1.6
—
—
—
0
0
5
13
3.85
1.71
11.4
7.3
4.9
6.6
mmol/l
—
5
13
5
13
3.85
1.71
1.6
1.4
—
—
—
0
0
17
89
1.92
1.70
1.1
1.1
—
—
—
0
0
6
19
3.17
1.66
1.3
1.4
—
—
—
0
0
8
31
2.59
1.66
1.4
2.4
—
—
—
0
0
13
62
2.11
1.65
1.9
1.5
2294.5
1823.7
ml
—
6
15
17
90
1.90
1.65
1.5
1.2
—
—
—
0
0
22
127
1.74
1.64
1.6
1.5
81.5
67.3
%
1.82
15
78
67
499
1.36
1.60
3.2
2.9
—
—
—
0
0
13
63
2.07
1.59
1.4
1.3
—
—
—
0
0
13
63
2.07
1.59
1.6
2.0
1.0
0.9
e9/l
—
8
35
14
70
2.01
1.59
3.0
2.7
10.5
11.1
%
0.21
14
70
6
20
3.01
1.58
1.2
1.1
—
—
—
0
0
7
26
2.70
1.58
1.6
1.5
—
—
—
0
0
7
26
2.70
1.58
1.1
1.0
—
—
—
0
0
5
15
3.34
1.52
3.8
7.5
—
—
—
0
0
6
21
2.86
1.50
1.0
1.0
—
—
—
0
0
6
21
2.86
1.50
1.2
1.1
—
—
—
0
0
823
8616
0.88
1.46
7.5
6.3
43.1
40.7
mmol/mol
6.79
758
7823
7
28
2.51
1.45
1.1
1.0
122.8
183.7
iu/ml
—
7
28
49
353
1.40
1.45
1.8
1.6
—
—
—
0
0
28
180
1.57
1.43
1.6
1.6
2.9
5.4
iu/l
—
9
57
106
861
1.25
1.37
2.0
2.1
152.5
147.6
ug/g
0.04
89
666
14
75
1.87
1.34
6.9
1.7
—
—
—
0
0
19
306
0.62
1.30
1.1
1.2
—
—
—
0
0
913
9464
0.88
1.27
36.6
15.6
—
—
—
0
0
6
25
2.40
1.24
1.0
1.4
—
—
—
0
0
75
593
1.28
1.23
5.1
3.8
—
—
—
0
0
12
63
1.91
1.22
2.6
2.6
—
—
—
0
0
5
19
2.64
1.21
2.0
1.3
—
—
—
0
0
13
71
1.84
1.19
12.4
16.5
—
—
—
0
0
19
117
1.63
1.18
2.5
4.1
274.4
350.2
umol/l
0.84
12
105
16
94
1.71
1.17
1.4
1.3
13.0
25.7
%
1.68
11
54
798
8317
0.90
1.16
4.8
4.5
2.0
2.2
mu/l
0.67
718
7396
10
50
2.01
1.16
3.1
1.6
—
—
—
0
0
209
2357
0.86
1.15
1.6
1.6
1.4
1.3
mmol/l
1.42
179
1952
21
134
1.58
1.14
1.5
1.3
—
—
—
0
0
45
335
1.35
1.14
6.3
4.7
—
—
—
0
0
7
31
2.26
1.10
1.6
2.7
—
—
—
0
0
12
66
1.82
1.09
3.7
3.4
7.4
7.4
ph
—
5
23
11
59
1.87
1.07
2.5
3.0
—
—
—
0
0
57
723
0.78
1.07
1.7
2.2
13.3
12.6
nmol/l
0.28
45
614
5
22
2.28
1.03
2.4
2.7
—
—
—
0
0
5
22
2.28
1.03
1.2
1.1
—
—
—
0
0
504
4724
1.11
1.03
5.0
4.0
0.0
0.0
estimate
0.50
108
867
11
189
0.58
1.01
1.0
1.0
—
—
—
0
0
11
61
1.81
0.98
1.2
1.2
—
—
—
0
0
496
4661
1.10
0.95
6.7
5.3
0.0
0.0
estimate
0.00
112
891
0
32
0.00
0.95
0.0
1.1
—
—
—
0
0
6
27
2.23
0.93
1.0
1.2
75.2
58.5
%
—
6
22
10
55
1.82
0.92
1.7
1.6
—
—
—
0
0
69
828
0.82
0.83
1.6
1.6
—
—
—
0
0
244
2227
1.12
0.82
4.8
3.8
—
—
—
0
0
12
73
1.65
0.81
1.7
1.2
—
—
—
0
0
283
2606
1.11
0.81
5.5
4.2
0.0
0.0
estimate
0.50
101
839
950
9739
0.91
0.81
43.9
19.5
4.0
4.0
mmol/l
1.75
929
9429
145
1285
1.14
0.79
1.3
1.2
—
—
—
0
0
0
24
0.00
0.79
0.0
1.7
—
—
—
0
0
24
327
0.73
0.79
2.7
3.0
60.4
74.8
u/ml
0.20
24
317
8
48
1.67
0.78
1.0
1.1
184.8
460.1
u/l
—
8
42
32
243
1.32
0.77
2.4
2.3
—
—
—
0
0
18
124
1.46
0.75
3.8
3.3
62.1
57.1
%
—
9
82
5
24
2.09
0.74
2.4
1.2
18.4
17.9
%
—
5
15
5
24
2.09
0.74
2.0
1.4
—
—
—
0
0
28
210
1.34
0.74
1.3
1.5
—
—
—
0
0
16
108
1.49
0.73
1.2
1.2
—
—
—
0
0
16
108
1.49
0.73
3.5
1.3
—
—
—
0
0
950
9721
0.92
0.72
43.8
19.4
139.2
139.6
mmol/l
4.22
930
9424
7
41
1.71
0.70
1.0
1.0
—
—
—
0
0
14
93
1.51
0.69
3.6
1.2
—
—
—
0
0
9
146
0.61
0.69
1.4
1.5
—
—
—
0
0
7
42
1.67
0.68
1.4
1.3
—
—
—
0
0
105
922
1.15
0.67
4.5
3.4
—
—
—
0
0
40
321
1.25
0.66
24.7
11.2
—
—
—
0
0
14
94
1.49
0.66
1.4
1.3
—
—
—
0
0
16
111
1.45
0.66
3.5
1.3
—
—
—
0
0
7
44
1.59
0.65
1.1
1.1
—
—
—
0
0
6
103
0.58
0.62
1.0
1.2
—
—
—
0
0
16
113
1.42
0.61
2.6
1.3
—
—
—
0
0
16
113
1.42
0.61
3.5
1.3
—
—
—
0
0
0
21
0.00
0.60
0.0
1.3
—
—
—
0
0
12
80
1.50
0.59
3.7
3.0
—
—
—
0
0
0
22
0.00
0.59
0.0
1.6
—
—
—
0
0
11
72
1.53
0.59
1.5
1.7
—
—
—
0
0
16
114
1.41
0.58
3.5
1.3
—
—
—
0
0
76
660
1.16
0.58
1.6
1.4
—
—
—
0
0
10
64
1.57
0.58
1.0
1.2
—
—
—
0
0
0
23
0.00
0.58
0.0
1.0
—
—
—
0
0
0
23
0.00
0.58
0.0
1.1
—
—
—
0
0
0
23
0.00
0.58
0.0
1.0
—
—
—
0
0
0
23
0.00
0.58
0.0
1.0
—
—
—
0
0
8
54
1.48
0.57
1.1
1.1
—
—
—
0
0
256
2398
1.08
0.53
1.7
1.7
425.4
12731437.9
pmol/l
1.26
195
1948
6
39
1.54
0.53
1.3
1.7
—
—
—
0
0
109
981
1.12
0.51
1.4
1.3
—
—
—
0
0
66
574
1.16
0.51
3.7
2.8
0.2
0.3
e6/l
0.71
66
557
18
135
1.34
0.51
1.2
1.1
—
—
—
0
0
7
46
1.52
0.48
1.0
1.3
—
—
—
0
0
7
46
1.52
0.48
1.0
1.3
—
—
—
0
0
7
48
1.46
0.46
1.1
1.5
—
—
—
0
0
16
120
1.34
0.46
1.0
1.1
—
—
—
0
0
14
103
1.36
0.45
1.2
1.4
281.9
277.5
mosm/kgh2o
—
9
76
18
231
0.78
0.45
1.1
1.1
—
—
—
0
0
46
534
0.86
0.45
2.2
2.6
—
18.5
—
0
14
47
404
1.17
0.44
1.1
1.2
162.7
137.5
iu/ml
0.14
11
155
139
1283
1.09
0.43
1.3
1.2
85.5
43.0
iu/ml
0.45
39
386
15
113
1.33
0.42
1.7
2.2
—
—
—
0
0
5
33
1.52
0.41
1.0
1.1
—
63.1
—
0
7
5
33
1.52
0.41
1.0
1.2
—
—
—
0
0
8
60
1.33
0.40
2.9
2.2
—
—
—
0
0
16
124
1.29
0.38
1.4
1.3
—
—
—
0
0
16
124
1.29
0.38
2.1
2.7
—
—
—
0
0
221
2092
1.07
0.37
5.5
4.4
1.0
1.0
kg/l
0.15
32
316
5
80
0.62
0.35
1.2
1.2
—
—
—
0
0
132
1230
1.08
0.35
1.4
1.4
—
—
—
0
0
33
381
0.86
0.33
1.2
1.3
—
—
—
0
0
44
390
1.13
0.31
2.4
3.0
0.3
0.3
g/l
0.45
20
150
7
54
1.30
0.30
1.0
1.2
144.7
138.0
nmol/l
—
7
54
327
3153
1.05
0.30
5.9
4.1
—
—
—
0
0
707
6932
1.04
0.30
5.1
4.0
20.1
14.2
mm/h
11.15
656
6298
16
129
1.24
0.30
4.1
4.6
—
—
—
0
0
45
401
1.13
0.29
1.2
1.2
—
—
—
0
0
161
1527
1.06
0.27
1.6
1.5
2.7
2.7
g/l
0.00
97
863
29
332
0.87
0.27
1.1
1.1
—
134.1
—
0
10
11
86
1.28
0.26
1.0
1.2
—
92.8
—
0
7
725
7361
0.97
0.25
48.2
21.4
327.6
331.9
g/l
21.96
714
7276
74
686
1.08
0.24
3.8
3.4
—
—
—
0
0
9
76
1.18
0.24
1.1
1.1
—
—
—
0
0
5
38
1.32
0.23
1.6
2.1
82.8
53.6
umol/l
—
5
26
17
200
0.85
0.23
1.4
1.3
1036.8
836.7
e6/l
0.08
17
163
17
200
0.85
0.23
1.4
1.3
17.8
49.7
e6/l
0.49
17
157
5
40
1.25
0.22
1.6
2.1
—
—
—
0
0
5
41
1.22
0.22
4.2
3.7
—
—
—
0
0
662
6719
0.97
0.22
3.8
3.7
15.2
15.1
pmol/l
0.63
587
5935
0
10
0.00
0.21
0.0
1.6
—
—
—
0
0
0
10
0.00
0.21
0.0
1.6
—
—
—
0
0
0
10
0.00
0.21
0.0
1.7
—
—
—
0
0
0
11
0.00
0.21
0.0
1.4
—
1.8
—
0
11
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
0
12
0.00
0.21
0.0
1.0
—
—
—
0
0
0
13
0.00
0.21
0.0
1.0
—
-3.7
—
0
7
0
13
0.00
0.21
0.0
1.0
—
—
—
0
0
256
2480
1.04
0.20
5.0
3.7
—
—
—
0
0
6
48
1.25
0.20
4.0
3.5
—
—
—
0
0
6
51
1.18
0.19
2.0
3.4
—
52.5
—
0
5
20
227
0.88
0.18
1.3
1.3
471.6
532.4
mg/l
0.34
20
211
677
6679
1.03
0.17
5.7
4.2
—
—
—
0
0
46
427
1.08
0.16
2.1
2.0
—
—
—
0
0
935
9269
1.03
0.16
37.9
16.2
33.9
27.3
mg/l
7.67
882
7543
14
120
1.17
0.16
1.1
1.1
—
—
—
0
0
9
81
1.11
0.15
1.1
1.1
—
—
—
0
0
62
588
1.06
0.13
1.1
1.2
—
—
—
0
0
162
1663
0.97
0.12
1.2
1.2
1.1
2.0
u/ml
1.00
29
414
51
537
0.95
0.11
1.3
1.3
—
—
—
0
0
10
86
1.16
0.11
1.1
1.2
—
—
—
0
0
5
47
1.06
0.09
1.4
1.7
10.6
9.2
mmol/l
—
5
41
105
1077
0.97
0.08
5.3
4.5
—
—
—
0
0
371
3669
1.01
0.07
2.2
2.3
—
—
—
0
0
8
75
1.07
0.07
1.1
1.1
—
—
—
0
0
9
87
1.03
0.07
1.3
1.2
—
—
—
0
0
57
586
0.97
0.05
2.8
3.0
4.9
4.2
e9/l
0.74
33
428
20
211
0.95
0.04
1.2
1.7
—
—
—
0
0
123
1211
1.02
0.04
1.2
1.2
31.1
13.6
u/ml
0.45
37
416
17
176
0.96
0.00
1.2
1.2
—
—
—
0
0
797
7973
1.00
0.00
40.1
17.7
36.1
38.7
%
6.92
468
4979
24
235
1.02
0.00
5.2
3.5
26.7
27.0
mg/l
0.02
18
153
732
7314
1.00
0.00
44.9
19.6
14.8
13.9
%
32.11
713
7121
56
564
0.99
0.00
2.6
2.5
—
—
—
0
0
27
270
1.00
0.00
1.9
1.6
—
—
—
0
0
13
131
0.99
0.00
1.0
1.1
—
—
—
0
0
10
99
1.01
0.00
1.3
1.1
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
172.9
—
0
7
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
0
7
0.00
0.00
0.0
5.9
—
0.3
—
0
7
0
7
0.00
0.00
0.0
4.4
—
—
—
0
0
0
6
0.00
0.00
0.0
1.7
—
—
—
0
0
0
8
0.00
0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
0.00
0.0
1.1
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
9
90
1.00
0.00
1.6
1.5
—
—
—
0
0
0
5
0.00
0.00
0.0
1.6
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint I9_ARTEMBTHRLOW and mortality.

Females

Parameter HR [95% CI] p-value
I9_ARTEMBTHRLOW 2.851 [2.42, 3.37] < 0.001
Birth year 0.994 [0.99, 1.0] 0.168

During the follow-up period (1.1.1998 — 31.12.2019), 2881 out of 4466 females with I9_ARTEMBTHRLOW died.

Males

Parameter HR [95% CI] p-value
I9_ARTEMBTHRLOW 2.71 [2.34, 3.13] < 0.001
Birth year 0.99 [0.98, 1.0] 0.033

During the follow-up period (1.1.1998 — 31.12.2019), 2545 out of 4597 males with I9_ARTEMBTHRLOW died.

Mortality risk

Mortality risk for people of age

years, who have I9_ARTEMBTHRLOW.

N-year risk Females Males
1 0.196% 0.666%
5 1.632% 3.398%
10 3.837% 8.646%
15 7.118% 16.2%
20 12.897% 25.911%

Relationships between endpoints

Index endpoint: I9_ARTEMBTHRLOW – Arterial embolism and thrombosis of lower extremity artery

GWS hits: 1

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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