neovascular glaucoma: Neovascular glaucoma is the most common type of secondary glaucoma, usually caused by diabetic retinopathy, central retinal vein occlusion and carotid artery obstruction but sometimes by trauma, uvietis or ocular tumors, and characterized by severe eye pain, synechial angle glaucoma, high intraocular pressure and leading to loss of vision.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleNone |
520210 |
2. Check conditionsNone |
520210 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
1554 |
4. Check minimum number of eventsNone |
1554 |
5. Include endpointsNone |
1554 |
6. Filter based on genotype QC (FinnGen only) |
1554 |
Control definitions (FinnGen only)
- Control exclude
- DM_RETINOPATHY
Extra metadata
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- H40
- Name in latin
- Glaucoma [secundarium] post aliam morbositatem oculi
Similar endpoints
↥List of similar endpoints to
Neovascular glaucoma
based on the number of shared cases.
Similar with more cases:
- Glaucoma secondary to other eye disorders
- Glaucoma
- Diseases of the eye and adnexa
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 13210 | 6427 | 6667 |
| Only index persons | 11515 | 5648 | 5867 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.18 | 0.18 | 0.19 |
| Only index persons | 0.22 | 0.21 | 0.22 |
| Median age at first event (years) | |||
| Whole population | 69.00 | 71.81 | 66.26 |
| Only index persons | 67.58 | 70.30 | 64.96 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 1554 | 716 | 838 |
| Unadjusted period prevalence (%) | 0.31 | 0.24 | 0.37 |
| Median age at first event (years) | 63.75 | 60.19 | 66.79 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 1412
- Matched controls
- 14120
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
S01EA05
ATC
brimonidine; ophthalmic (sympathomimetics in glaucoma therapy)
65.7
323.0
614
163
H40.5
ICD-10 Finland
Glaucoma secondary to other eye disorders
4503599627370496.0
323.0
1411
*
114
Kela drug reimbursment
Glaucoma
43.5
323.0
1003
753
Z96.1
ICD-10 Finland
Presence of intraocular lens
12.9
323.0
723
1060
S01ED01
ATC
timolol; ophthalmic
34.1
323.0
562
268
S01CA01
ATC
dexamethasone and antiinfectives; ophthalmic (ophth., corticosteroids and antiinfectives in comb.)
11.5
323.0
1108
3396
S01ED51
ATC
timolol, combinations; ophthalmic
80.9
323.0
1106
602
S01EE01
ATC
latanoprost; ophthalmic
27.4
323.0
676
457
S01EC01
ATC
acetazolamide; systemic
84.7
323.0
586
117
WX140
NOMESCO Finland
Parabulbar anesthesy
27.0
308.5
440
233
H20.0
ICD-10 Finland
Acute and subacute iridocyclitis
29.1
290.2
403
191
S01EC04
ATC
brinzolamide; ophthalmic
23.0
287.5
432
265
H20.1
ICD-10 Finland
Chronic iridocyclitis
79.5
282.9
316
51
CKD05
NOMESCO Finland
Puncture of vitreous body with injection of medication
24.5
265.4
389
216
CKC12
NOMESCO Finland
Photocoagulation of retina
35.6
265.0
347
128
XCW99
NOMESCO Finland
Other investigative procedure of eye
11.0
251.9
543
757
S01EA03
ATC
apraclonidine; ophthalmic
81.4
247.5
276
42
CHF05
NOMESCO Finland
Transscleral laser coagulation of ciliary body
119.6
232.0
247
25
CKD65
NOMESCO Finland
Pars plana or pars plicata vitrectomy
46.1
231.5
285
77
H40.0
ICD-10 Finland
Glaucoma suspect
12.7
222.6
432
474
XCK00
NOMESCO Finland
Perimetry
12.2
219.0
433
492
H43.1
ICD-10 Finland
Vitreous haemorrhage
44.0
201.9
251
69
CJE20
NOMESCO Finland
Phakoemulsification with implantation of artificial lens in posterior chamber
5.6
198.0
881
3205
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
5.6
196.6
950
3789
XCK10
NOMESCO Finland
Photography of fundus of eye
9.5
196.4
452
667
H33.0
ICD-10 Finland
Retinal detachment with retinal break
27.7
193.9
271
120
CK2X4
NOMESCO Finland
Optical coherence tomography (OCT) of ocular fundus
10.4
186.9
403
524
S01EE03
ATC
bimatoprost; ophthalmic
23.3
175.2
258
134
Z01.0
ICD-10 Finland
Examination of eyes and vision
6.4
168.5
529
1201
S01EE05
ATC
tafluprost; ophthalmic
17.5
167.4
274
192
H34.8
ICD-10 Finland
Other retinal vascular occlusions
28.7
166.7
230
95
CKD40
NOMESCO Finland
Endophotocoagulation of retina
46.0
164.1
202
51
S01EC03
ATC
dorzolamide; ophthalmic
23.5
161.6
237
120
CHD50
NOMESCO Finland
Shunt operation on anterior chamber
261.0
160.9
162
7
H3603, E103
ICD-10 Finland
NA
+∞
152.9
144
*
H26.2
ICD-10 Finland
Complicated cataract
51.1
151.8
183
41
H36.03
ICD-10 Finland
Proliferative diabetic retinopathy
+∞
143.2
135
*
S01EX03
ATC
NA
16.5
142.8
238
171
H40.13
ICD-10 Finland
Chronic glaucoma with open ventricular angle
10.8
139.9
287
325
S01EC54
ATC
brinzolamide, combinations; ophthalmic
29.5
137.6
188
73
H3603, E113
ICD-10 Finland
NA
+∞
135.6
128
*
CKD20
NOMESCO Finland
Removal of vitreous body substitute
131.4
133.8
142
12
S01BA07
ATC
fluorometholone; ophthalmic (corticosteroids, plain)
31.3
133.2
179
65
S01BC03
ATC
diclofenac; ophthalmic
19.5
131.5
205
122
H40.4
ICD-10 Finland
Glaucoma secondary to eye inflammation
278.7
126.2
127
5
E10.7
ICD-10 Finland
Type 1 diabetes mellitus, With multiple complications
43.0
123.5
154
40
CKC15
NOMESCO Finland
Panretinal photocoagulation
121.2
123.4
132
12
E10.3
ICD-10 Finland
Type 1 diabetes mellitus, With ophthalmic complications
42.4
121.6
152
40
CJB10
NOMESCO Finland
Laser discission of secondary cataract
6.8
121.3
342
636
XCH00
NOMESCO Finland
Eye pressure measurement
11.9
118.6
229
226
S01BA01
ATC
dexamethasone; ophthalmic (corticosteroids, plain)
12.7
117.4
219
201
S01EE04
ATC
travoprost; ophthalmic
15.2
117.2
201
152
CKC20
NOMESCO Finland
Cryopexy of undetached retina
145.5
114.0
120
9
H26.4
ICD-10 Finland
After-cataract
6.1
113.7
351
729
A10AC01
ATC
insulin (human); parenteral (insulins and analog. for injection, intermediate-acting)
7.7
113.1
286
451
A10AA02
ATC
NA
15.7
109.6
185
134
CKD15
NOMESCO Finland
Injection of vitreous substitute
85.8
106.0
118
15
A10AB01
ATC
insulin (human); parenteral (insulins and analog. for injection, fast-acting)
16.3
105.5
175
121
S01BA04
ATC
prednisolone; ophthalmic (corticosteroids, plain)
14.9
104.8
181
138
CKC10
NOMESCO Finland
Local photocoagulation of retina
35.7
104.8
136
42
CHF15
NOMESCO Finland
Cryotherapy of ciliary body
546.5
104.0
102
*
A10AA01
ATC
NA
24.4
100.8
145
66
H40.9
ICD-10 Finland
Glaucoma, unspecified
17.5
99.8
161
103
A10AE04
ATC
insulin glargine; parenteral
6.4
98.8
288
547
A10AB05
ATC
insulin aspart; parenteral (insulins and analog. for injection, fast-acting)
7.5
97.3
247
386
ZXA05
NOMESCO Finland
Left side
3.6
96.6
578
2266
S01FA04
ATC
cyclopentolate; ophthalmic
29.3
96.1
131
49
H36.01
ICD-10 Finland
Diabetic maculopathy
879.3
85.5
83
*
CKD10
NOMESCO Finland
Insufflation of vitreous cavity
19.9
85.5
131
72
H40.10
ICD-10 Finland
Capsular glaucoma with pseudoexfoliation on the anterior lens capsule
10.8
85.2
171
178
H25.1
ICD-10 Finland
Senile nuclear cataract
3.2
84.3
602
2633
H21.1
ICD-10 Finland
Other vascular disorders of iris and ciliary body
437.6
83.9
83
*
ZXA00
NOMESCO Finland
Right side
3.3
83.8
585
2514
E10.9
ICD-10 Finland
Type 1 diabetes mellitus, Without complications
12.6
83.1
154
136
A10AB04
ATC
insulin lispro; parenteral (insulins and analog. for injection, fast-acting)
16.5
81.6
134
89
CK2S4
NOMESCO Finland
Plain photography of ocular fundus
7.1
81.4
214
347
E11.3
ICD-10 Finland
Type 2 diabetes mellitus, with ophthalmic complications
16.6
80.6
132
87
T89
ICPC
Diabetes insulin dependent
13.4
76.9
138
113
H3601, E113
ICD-10 Finland
NA
398.1
76.5
76
*
H36.09*E10.3
ICD-10 Finland
Insulin-dependent diabetes mellitus - Diabetic retinopathy
167.1
75.8
79
5
H3601, E103
ICD-10 Finland
NA
+∞
75.7
72
*
H16.0
ICD-10 Finland
Corneal ulcer
8.2
74.1
175
240
CS444
NOMESCO Finland
Visual field testing with Octopus automated perimetry
10.9
73.4
146
148
A10AE05
ATC
insulin detemir; parenteral
7.4
71.5
180
272
E11.7
ICD-10 Finland
Type 2 diabetes mellitus, with multiple complications
7.1
70.7
183
288
2500B
ICD-9 Finland
Diabetes mellitus without mention of complication[DIABETES MELLITUS SINE COMPLICATIONE ,TYYPPI I]
22.1
68.5
101
49
25000
ICD-8 Finland
Diabetes mellitus, Sine complicatione
13.5
68.5
122
98
S01CA02
ATC
prednisolone and antiinfectives; ophthalmic (ophth., corticosteroids and antiinfectives in comb.)
18.3
68.0
107
63
WX100
NOMESCO Finland
Conjunctival surface anesthesia
4.1
67.8
304
892
CHB10
NOMESCO Finland
Puncture of anterior chamber of eye with irrigation
59.6
67.5
79
14
H40.8
ICD-10 Finland
Other glaucoma
58.8
66.5
78
14
H3600, E103
ICD-10 Finland
NA
+∞
66.2
63
*
N08.39*E10.2
ICD-10 Finland
Insulin-dependent diabetes mellitus - Diabetic nephropathy
54.9
65.8
78
15
S01ED02
ATC
betaxolol; ophthalmic
18.8
62.4
97
55
CKD92
NOMESCO Finland
Combined vitrectomy and retinal procedure
18.5
62.0
97
56
XCD10
NOMESCO Finland
Electrophysiological examination of eye
10.8
61.6
122
122
H21.0
ICD-10 Finland
Hyphaema
54.9
61.6
73
14
S01EB01
ATC
pilocarpine; ophthalmic
23.4
60.9
88
40
S01BC05
ATC
ketorolac; ophthalmic
6.3
59.9
170
301
CKD70
NOMESCO Finland
Excision of preretinal or epiretinal membrane
17.9
59.4
94
56
H40.3
ICD-10 Finland
Glaucoma secondary to eye trauma
208.6
58.5
60
*
H36.00
ICD-10 Finland
Diabetic background retinopathy
95.7
58.4
64
7
103
Kela drug reimbursment
Diabetes, insulin-treated
2.8
58.2
501
2339
H3600, E113
ICD-10 Finland
NA
591.3
58.1
57
*
E10.2
ICD-10 Finland
Type 1 diabetes mellitus, With renal complications
49.0
57.9
70
15
H27.0
ICD-10 Finland
Aphakia
42.1
57.8
72
18
CHC05
NOMESCO Finland
Iridotomy
12.2
56.0
104
91
CKD93
NOMESCO Finland
Extended combined procedure on vitreous body and retina
47.5
56.0
68
15
H36.09*E11.3
ICD-10 Finland
Non-insulin-dependent diabetes mellitus - Diabetic retinopathy
66.9
55.7
64
10
H04AA01
ATC
glucagon; nasal, parenteral
16.8
55.6
90
57
CHD05
NOMESCO Finland
Selective lasertrabeculoplasty
8.2
54.7
127
168
S01FA01
ATC
atropine; ophthalmic
33.4
53.5
70
22
CKD91
NOMESCO Finland
Extended vitrectomy through pars plana
20.3
52.4
79
41
A10AD01
ATC
insulin (human); parenteral (insulins and analog. for injection, intermediate- or long-acting comb. with fast-acting)
12.3
52.0
96
83
H26.02
ICD-10 Finland
Presenil cataract
9.8
50.9
106
116
CHD65
NOMESCO Finland
Nonpenetrating glaucoma surgery
19.8
50.6
77
41
L04AX03
ATC
methotrexate; systemic (immunosuppressants)
4.1
49.3
209
570
CHD99
NOMESCO Finland
Other filtering operation
33.4
49.0
64
20
H35.39
ICD-10 Finland
Degeneration of macula and posterior pole
8.5
48.9
111
141
H54.4
ICD-10 Finland
Blindness, monocular
71.3
48.4
55
8
H34.1
ICD-10 Finland
Central retinal artery occlusion
35.9
48.2
62
18
CKD94
NOMESCO Finland
Combined vitrectomy and procedure on lens through pars plana
17.3
48.2
77
47
TCA20
NOMESCO Finland
Peribulbar therapeutic injection into orbit
70.0
47.4
54
8
H04.10
ICD-10 Finland
Dry eye syndrome
3.9
47.3
216
629
202
Kela drug reimbursment
Connective tissue diseases, rheumatoid arthritis and comparable disease
3.5
47.1
250
823
XCD20
NOMESCO Finland
Photoangiography of eye
13.1
46.4
83
67
E10.1
ICD-10 Finland
Type 1 diabetes mellitus, With ketoacidosis
48.5
46.4
56
12
215
Kela drug reimbursment
Diabetes, non-insulin-treated
2.6
45.8
405
1872
H40.20
ICD-10 Finland
Acute glaucoma with closed ventricular angle
31.3
45.2
60
20
Z94.7
ICD-10 Finland
Corneal transplant status
43.9
44.7
55
13
WX002
NOMESCO Finland
Sedation and analgesia
2.7
44.3
374
1677
ZXA10
NOMESCO Finland
Bilateral
2.7
44.3
355
1540
WX142
NOMESCO Finland
Sub-tenon anesthesy
39.3
42.1
53
14
XCH05
NOMESCO Finland
Eye pressure longterm registration
21.6
42.1
62
30
CS5Z4
NOMESCO Finland
Specialised imaging for glaucoma
9.0
42.0
91
107
H33.4
ICD-10 Finland
Traction detachment of retina
113.4
41.0
44
*
E10.00
ICD-10 Finland
Insulin-dependent diabetes diabetic hypoglycemic coma
34.3
40.9
53
16
TCG10
NOMESCO Finland
Removal of sutures from cornea
24.7
40.4
57
24
E10
ICD-10 Finland
Type 1 diabetes mellitus
16.0
40.4
66
43
CHD00
NOMESCO Finland
Laser trabeculoplasty
12.8
39.5
71
58
H18.1
ICD-10 Finland
Bullous keratopathy
66.3
39.3
45
7
CA1AE
NOMESCO Finland
Eye and orbita ultrasound examination
48.5
39.0
47
10
H54.2
ICD-10 Finland
Moderate visual impairment, binocular
15.5
38.7
64
43
138
Kela drug reimbursment
Severe anaemia associated with chronic renal failure
8.3
37.7
86
110
N08.39
ICD-10 Finland
Glomerular disorders in diabetes mellitus microalbuminuria
40.5
37.7
47
12
CKC60
NOMESCO Finland
Local buckling of sclera using implant
30.4
37.5
50
17
CGG45
NOMESCO Finland
Full thickness transplantation of cornea using homograft
195.0
37.0
38
*
H26.3
ICD-10 Finland
Drug-induced cataract
26.4
36.9
51
20
SPAT1262
SPAT
Handing over of treatment supplies
2.6
36.5
315
1410
CS424
NOMESCO Finland
Visual field testing with Goldmann perimetry
18.8
36.4
56
31
190
Kela drug reimbursment
Lanthanum carbonate, sevelamer and sucroferric oxyhydroxide
25.8
36.0
50
20
H20.9
ICD-10 Finland
Iridocyclitis, unspecified
16.0
35.0
57
37
H35.31
ICD-10 Finland
Senile macular degeneration (atrophic)(exudative)
5.2
34.2
110
224
H40
ICD-10 Finland
Glaucoma
10.8
33.9
66
64
123
Kela drug reimbursment
Chronic disorders of vitamin D metabolism
7.6
33.8
81
112
E10.5
ICD-10 Finland
Type 1 diabetes mellitus, With peripheral circulatory complications
123.0
33.8
36
*
V03AE01
ATC
polystyrene sulfonate; oral
13.4
33.1
58
45
H36.09
ICD-10 Finland
Diabetic retinopathy (E10-E14+ with common fourth character .3)
76.0
33.0
37
5
CKD50
NOMESCO Finland
Endodiathermy of retina
50.0
32.6
39
8
313
Kela drug reimbursment
Abatacept, adalimumab, anakinra, certolizumab pegol, etanercept, golimumab, infliximab, ixekizumab, sarilumab, secukinumab, tocilizumab and ustekinumab (rheumatoid diseases)
7.1
32.6
82
122
A10AA03
ATC
NA
16.8
32.6
52
32
TCW99
NOMESCO Finland
Other minor procedure in eye surgery
9.5
32.6
68
75
CHD15
NOMESCO Finland
Trabeculectomy and iridectomy
15.7
32.3
53
35
CKC70
NOMESCO Finland
Circular buckling of sclera
33.2
32.3
42
13
CS1H4
NOMESCO Finland
Retinal nerve fibre layer imaging
11.6
32.0
60
54
H44.5
ICD-10 Finland
Degenerated conditions of globe
89.7
31.9
35
*
H57.1
ICD-10 Finland
Ocular pain
6.6
31.8
84
134
3641A
ICD-9 Finland
Disorders of iris and ciliary body, Chronic iridocyclitis
116.0
31.8
34
*
E10.6
ICD-10 Finland
Type 1 diabetes mellitus, With other specified complications
48.7
31.7
38
8
CKC30
NOMESCO Finland
Cryopexy of detached retina
27.7
31.6
43
16
CS494
NOMESCO Finland
Other visual field testing
7.2
31.4
78
114
CS3P4
NOMESCO Finland
Optic nerve head stereophotography
14.4
31.3
53
38
TK800
NOMESCO Finland
Hemodialysis
7.7
31.2
74
101
L01BA01
ATC
methotrexate; systemic (folic acid analog.)
4.9
30.8
104
224
L04AB04
ATC
adalimumab; parenteral
8.7
30.7
67
80
E10.8
ICD-10 Finland
Type 1 diabetes mellitus, With unspecified complications
19.8
30.6
46
24
S01FA02
ATC
scopolamine; ophthalmic
12.1
30.6
56
48
Z49.1
ICD-10 Finland
Extracorporeal dialysis
11.2
30.4
58
54
L97
ICD-10 Finland
Ulcer of lower limb, not elsewhere classified
5.2
30.4
97
196
A11CC03
ATC
alfacalcidol; systemic
7.0
30.3
76
113
A10AE06
ATC
insulin degludec; parenteral
7.9
30.0
70
93
E10.4
ICD-10 Finland
Type 1 diabetes mellitus, With neurological complications
27.8
28.1
38
14
CKD95
NOMESCO Finland
Extended combined vitectomy and lens procedure through pars plana
102.1
27.7
30
*
C03CA01
ATC
furosemide; systemic
1.9
27.6
515
3212
3656X
ICD-9 Finland
Glaucoma associated with other ocular disorders[GLAUCOMA SECUNDARIA ALIA SEU NUD]
+∞
27.2
26
*
H36.02
ICD-10 Finland
Preproliferative diabetic retinopathy
+∞
27.2
26
*
TCF00
NOMESCO Finland
Subconjunctival therapeutic injection
63.3
27.0
31
5
T85.2
ICD-10 Finland
Mechanical complication of intraocular lens
22.9
26.6
38
17
C08CA01
ATC
amlodipine; oral
1.9
26.3
539
3462
H28.0*E10.3
ICD-10 Finland
Other specified diabetes mellitus - Diabetic cataract
+∞
26.1
25
*
Z94.0
ICD-10 Finland
Kidney transplant status
14.1
25.9
44
32
E11.5
ICD-10 Finland
Type 2 diabetes mellitus, with peripheral circulatory complications
7.0
25.9
65
97
H30.2
ICD-10 Finland
Posterior cyclitis
27.6
25.8
35
13
L04AA01
ATC
[U] ciclosporin; systemic
8.4
25.8
57
70
H40.6
ICD-10 Finland
Glaucoma secondary to drugs
95.2
25.7
28
*
CS434
NOMESCO Finland
Visual field testing with Humphrey automated perimetry
6.1
25.6
71
121
281
Kela drug reimbursment
Abatacept, adalimumab, anakinra, certolizumab pegol, etanercept, golimumab, infliximab, ixekizumab, sarilumab, secukinumab and tocilizumab
6.3
25.5
69
114
QDB10
NOMESCO Finland
Major dressing of wound of skin of lower limb
3.9
25.5
110
301
C09AA02
ATC
enalapril; systemic
2.1
25.2
348
1914
SPAT1148
SPAT
Treatment of chronic ulcer or burn
2.4
25.2
239
1105
TCA15
NOMESCO Finland
Retrobulbar therapeutic injection into orbit
254.4
24.7
25
*
M08.4
ICD-10 Finland
Pauciarticular juvenile arthritis
32.7
24.7
32
10
TCG00
NOMESCO Finland
Protection of cornea and sclera with soft lens
32.7
24.7
32
10
CKD60
NOMESCO Finland
Anterior vitrectomy
12.6
24.6
44
36
BEF00
NOMESCO Finland
Continuous subcutaneous glucose monitoring
35.2
24.3
31
9
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.8
24.3
631
4360
M08.3
ICD-10 Finland
Juvenile polyarthritis (seronegative)
29.7
24.1
32
11
H54.0
ICD-10 Finland
Blindness, binocular
57.0
24.1
28
5
H16.9
ICD-10 Finland
Keratitis, unspecified
7.7
24.0
56
75
R5210
NOMESCO Finland
Assessment of the improvements needed in the living environment
23.2
24.0
34
15
KAS10
NOMESCO Finland
Allogenic transplantation of kidney from cadaver donor
16.2
23.7
38
24
N18.9
ICD-10 Finland
Chronic kidney disease, unspecified
3.2
23.7
134
453
PBL10
NOMESCO Finland
Construction of arteriovenous fistula from radial artery
11.9
23.5
43
37
A12AA04
ATC
calcium carbonate; oral
7.3
23.5
57
81
S01AX11
ATC
[U] ofloxacin; ophthalmic
3.9
23.0
97
260
H3603, E109
ICD-10 Finland
NA
+∞
23.0
22
*
H33.3
ICD-10 Finland
Retinal breaks without detachment
5.3
22.9
71
139
N18.8
ICD-10 Finland
Other chronic renal failure
5.0
22.8
75
157
A10AD05
ATC
insulin aspart; parenteral (insulins and analog. for injection, intermediate- or long-acting comb. with fast-acting)
7.1
22.6
56
82
127
Kela drug reimbursment
Transplant complication
8.3
22.5
50
62
H27.1
ICD-10 Finland
Dislocation of lens
18.3
22.2
34
19
V03AE02
ATC
sevelamer; oral
24.3
22.2
31
13
L04AA06
ATC
mycophenolic acid; systemic
7.0
22.2
55
81
I70.2
ICD-10 Finland
Atherosclerosis of arteries of extremities
2.5
22.1
185
798
CDC00
NOMESCO Finland
Enucleation of eye
+∞
21.9
21
*
36402
ICD-8 Finland
Iritis, Iridocyclitis, uveitis chronica
81.4
21.7
24
*
177
Kela drug reimbursment
Insulin glargine 300 U / ml
7.8
21.7
50
66
2501B
ICD-9 Finland
Diabetes mellitus, Diabetes with ketoacidosis[DIABETES MELLITUS CUM KETOACIDOSI ,TYYPPI I]
223.2
21.6
22
*
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
2.4
21.5
199
903
S01AD03
ATC
aciclovir; ophthalmic
4.1
21.5
86
220
B05DA
ATC
Isotonic solutions
16.5
21.5
34
21
I10
ICD-10 Finland
Essential (primary) hypertension
1.7
21.4
827
6364
N08.39*E11.2
ICD-10 Finland
Non-insulin-dependent diabetes mellitus - Diabetic nephropathy
9.8
20.9
42
44
G63.2*E10.4
ICD-10 Finland
Insulin-dependent diabetes mellitus - Diabetic polyneuropathy
37.8
20.8
26
7
H02AB06
ATC
prednisolone; systemic
1.7
20.7
644
4630
H25.8
ICD-10 Finland
Other senile cataract
2.3
20.6
203
948
137
Kela drug reimbursment
Uraemia requiring dialysis
12.2
20.6
37
31
NHQ40
NOMESCO Finland
Amputation of toe
7.2
20.5
50
72
E11.8
ICD-10 Finland
Type 2 diabetes mellitus, with unspecified complications
2.6
20.5
159
654
320
Kela drug reimbursment
Lanthanum carbonate, sevelamer and sucroferric oxyhydroxide
25.9
20.5
28
11
M08.0
ICD-10 Finland
Juvenile rheumatoid arthritis
25.9
20.5
28
11
A07EC01
ATC
sulfasalazine; oral, rectal
2.8
20.3
135
508
TNX10
NOMESCO Finland
Arthrocentesis, unspecified region, unspecified region
3.1
20.0
113
381
3663A
ICD-9 Finland
Cataract secondary to ocular disorders
19.1
20.0
30
16
3643
FHL
Vitrectomy through pars Plana
36.3
19.9
25
7
L04AD02
ATC
tacrolimus; systemic (calcineurin inhibitors)
15.6
19.8
32
21
C10AA01
ATC
simvastatin; oral
1.7
19.7
627
4514
196
Kela drug reimbursment
Paricalcitol and cinacalcet
29.4
19.7
26
9
C69.30
ICD-10 Finland
Malignant tumor of the chorioidea without histology
29.4
19.7
26
9
H26.1
ICD-10 Finland
Traumatic cataract
21.9
19.5
28
13
Z49.2
ICD-10 Finland
Other dialysis
14.8
19.4
32
22
H54.1
ICD-10 Finland
Severe visual impairment, binocular
46.7
19.2
23
5
2500A
ICD-9 Finland
Diabetes mellitus without mention of complication[DIABETES MELLITUS SINE COMPLICATIONE,TYYPPI II]
4.7
19.0
66
147
H10.3
ICD-10 Finland
Acute conjunctivitis, unspecified
3.3
19.0
100
321
Z90.0
ICD-10 Finland
Acquired absence of part of head and neck
55.8
19.0
22
*
37520
ICD-8 Finland
Glaucoma, Secondary
34.8
18.9
24
7
E11.9
ICD-10 Finland
Type 2 diabetes mellitus, without complications
1.9
18.7
343
2066
ZXC20
NOMESCO Finland
Use of chemical agents
4.7
18.7
64
141
J01FF01
ATC
clindamycin; systemic
1.8
18.6
367
2265
S01EX
ATC
Other antiglaucoma preparations
192.4
18.6
19
*
M45
ICD-10 Finland
Ankylosing spondylitis
5.5
18.6
55
103
N18.0
ICD-10 Finland
End-stage renal disease
8.5
18.5
40
48
ZX198
NOMESCO Finland
Other local administration
8.9
18.5
39
45
H19.1*B00.5
ICD-10 Finland
Herpesviral keratoconjunctivitis
10.2
18.4
36
36
SPAT1250
SPAT
Comprehensive monitoring of chronic illness
1.8
18.3
386
2437
XPX99
NOMESCO Finland
Other diagnostic examination of periferal vessel
2.8
18.3
124
472
B05DB
ATC
Hypertonic solutions
17.8
18.3
28
16
H35.6
ICD-10 Finland
Retinal haemorrhage
25.4
18.2
25
10
B03XA02
ATC
darbepoetin alfa; parenteral
5.5
18.1
54
102
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
1.7
18.1
453
3017
ZX120
NOMESCO Finland
Intravenous
2.4
18.0
162
723
H25.0
ICD-10 Finland
Senile incipient cataract
2.8
17.9
117
436
H3603, E107
ICD-10 Finland
NA
+∞
17.7
17
*
QDG20
NOMESCO Finland
Operation for chronic ulcer or fistula of skin of lower limb
10.5
17.7
34
33
I15.1
ICD-10 Finland
Hypertension secondary to other renal disorders
9.4
17.7
36
39
CKD99
NOMESCO Finland
Other intraoclular operations on vitreous body and retina
182.1
17.5
18
*
H04.5
ICD-10 Finland
Stenosis and insufficiency of lacrimal passages
5.5
17.5
52
98
PA6DE
NOMESCO Finland
Neck artery ultrasound examination with Doppler method
3.1
17.5
100
341
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
2.7
17.4
125
491
TCG40
NOMESCO Finland
Measurement of higher-grade errors of refraction
17.2
17.4
27
16
205
Kela drug reimbursment
Chronic hypertension
1.7
17.3
442
2951
SPAT1009
SPAT
Measurement of intraocular pressure
6.3
17.1
45
73
CKE60
NOMESCO Finland
Brachytherapy of choroid and retina
31.9
17.1
22
7
CKE65
NOMESCO Finland
Removal of brachytherapeutic plate from eye
31.9
17.1
22
7
H22.1*M45
ICD-10 Finland
Iridocyclitis in ankylosing spondylitis
50.6
17.0
20
*
R3120
NOMESCO Finland
Training in mobility skills
50.6
17.0
20
*
C69.32
ICD-10 Finland
Malignant tumor of the chorioidea melanoma
50.6
17.0
20
*
CJF30
NOMESCO Finland
Reduction of dislocation of artificial lens
22.2
16.9
24
11
T90
ICPC
Diabetes non-insulin dependent
1.9
16.9
306
1829
H20.8
ICD-10 Finland
Other iridocyclitis
14.3
16.8
28
20
S97
ICPC
Chronic ulcer skin
3.0
16.8
101
356
3793A
ICD-9 Finland
Other disorders of eye, Aphakia and other disorders of lens[APHAKIA]
64.1
16.8
19
*
3656F
ICD-9 Finland
Glaucoma associated with other ocular disorders[GLAUCOMA POST UVEITIDEM]
+∞
16.7
16
*
H3602, E103
ICD-10 Finland
NA
+∞
16.7
16
*
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
2.1
16.6
194
979
WX408
NOMESCO Finland
General anesthesy, balanced
1.8
16.5
363
2308
H33.5
ICD-10 Finland
Other retinal detachments
10.9
16.5
31
29
3610A
ICD-9 Finland
Retinal detachments and defects, Retinal detachment with retinal defect
20.3
16.4
24
12
CFD10
NOMESCO Finland
Repair of conjunctiva
30.4
16.1
21
7
H33.2
ICD-10 Finland
Serous retinal detachment
30.4
16.1
21
7
C02AC05
ATC
moxonidine; oral
3.3
16.1
84
269
H18.8
ICD-10 Finland
Other specified disorders of cornea
11.8
16.1
29
25
Z49.0
ICD-10 Finland
Preparatory care for dialysis
8.7
16.0
34
40
TPH04
NOMESCO Finland
Cathetrisation of vein
1.8
15.9
300
1810
A10BB01
ATC
glibenclamide; oral
3.0
15.8
95
333
CG2X4
NOMESCO Finland
Optical coherence tomography (OCT) of cornea
11.4
15.8
29
26
3626
FHL
Extracapsular cataract surgery and implantation of an artificial lens
4.5
15.7
55
125
H34.2
ICD-10 Finland
Other retinal artery occlusions
17.4
15.6
24
14
H25.2
ICD-10 Finland
Senile cataract, morgagnian type
11.9
15.6
28
24
KA2AE
NOMESCO Finland
Ultrasound examination transplanted kidney
13.9
15.5
26
19
3711
FHL
Cyclodiateria or cryocoagulation
161.7
15.5
16
*
H40.22
ICD-10 Finland
Chronic glaucoma with closed ventricular angle
7.5
15.5
36
49
S01EA02
ATC
dipivefrine; ophthalmic
10.2
15.5
30
30
E11.2
ICD-10 Finland
Type 2 diabetes mellitus, with renal complications
3.8
15.4
66
181
XCW10
NOMESCO Finland
Assessment of vision
16.2
15.3
24
15
CK2L4
NOMESCO Finland
Wide-field/panoramic imaging of ocular fundus
10.5
15.2
29
28
V03AE03
ATC
lanthanum carbonate; oral
28.9
15.2
20
7
NHQ30
NOMESCO Finland
Amputation of foot, transmetatarsal
18.0
15.2
23
13
H35.0
ICD-10 Finland
Background retinopathy and retinal vascular changes
18.0
15.2
23
13
2504B
ICD-9 Finland
Diabetes mellitus, Diabetes with renal manifestations[DIABETES MELLITUS CUM COMPLICATIONE OCULI ,TYYPPI I]
45.5
15.1
18
*
CG2T4
NOMESCO Finland
Topography assessment of cornea
9.3
14.7
30
33
CS2P4
NOMESCO Finland
Optic nerve head imaging
13.4
14.7
25
19
H43.8
ICD-10 Finland
Other disorders of vitreous body
2.5
14.7
119
502
CJF00
NOMESCO Finland
Secondary implantation of artificial lens in anterior chamber
25.3
14.7
20
8
3620B
ICD-9 Finland
Other retinal disorders, Diabetic retinopathy[RETINOPATHIA DIABETICA PROLIFERATIVA]
+∞
14.6
14
*
H34.9
ICD-10 Finland
Retinal vascular occlusion, unspecified
80.9
14.6
16
*
M14.6*E10.6
ICD-10 Finland
Insulin-dependent diabetes mellitus - Diabetic neuropathic
80.9
14.6
16
*
CKD45
NOMESCO Finland
Endocryotherapy of retina
151.5
14.5
15
*
F29
ICPC
Eye symptom/complaint other
2.5
14.5
115
481
S01FA06
ATC
tropicamide; ophthalmic
36.4
14.5
18
5
AA1AD
NOMESCO Finland
CT of head and brain
1.7
14.4
342
2214
KA2AT
NOMESCO Finland
Biopsy of transplanted kidney with ultrasound guidance
19.3
14.2
21
11
H18.2
ICD-10 Finland
Other corneal oedema
22.5
14.2
20
9
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
1.9
14.2
233
1337
CA1ME
NOMESCO Finland
Ultrasound oculometry
8.5
14.0
30
36
SPAT1229
SPAT
Assessment of need for aid
2.3
13.9
137
637
3708
FHL
Trabeculectomy or equivalent
24.0
13.8
19
8
SPAT1256
SPAT
Intramuscular and subcutaneous injection
1.6
13.7
538
3974
H18.6
ICD-10 Finland
Keratoconus
14.9
13.6
22
15
E10.01
ICD-10 Finland
Insulin-dependent diabetes diabetic coma with hyperglycemia
+∞
13.6
13
*
3649
FHL
Other measure in this category
+∞
13.6
13
*
H3602, E113
ICD-10 Finland
NA
+∞
13.6
13
*
E11.00
ICD-10 Finland
Non-insulin dependent diabetes diabetic hypoglycaemic coma
3.4
13.5
65
197
H40.19
ICD-10 Finland
Other primary glaucoma with open ventricular angle
13.0
13.4
23
18
B01AC04
ATC
clopidogrel; oral
1.8
13.4
237
1397
L04AA17
ATC
[U] adalimumab; parenteral
18.4
13.4
20
11
CJF15
NOMESCO Finland
Secondary implantation of skleral fixed artificial lens in posterior chamber
26.0
13.4
18
7
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
1.7
13.4
292
1838
S18
ICPC
Laceration/cut
1.6
13.4
525
3876
TJA35
NOMESCO Finland
Removal of peritoneal dialysis catheter
21.4
13.3
19
9
TK820
NOMESCO Finland
Peritoneal dialysis
21.4
13.3
19
9
S05.1
ICD-10 Finland
Contusion of eyeball and orbital tissues
5.2
13.2
40
78
SPAT1253
SPAT
Initiation, adjustment, discontinuation or repetition of medication
1.6
13.1
404
2803
CFW99
NOMESCO Finland
Other operation on conjunctiva
15.2
13.1
21
14
A28
ICPC
Limited function/disability NOS
1.8
13.1
239
1423
H35.30
ICD-10 Finland
Kuhnt-Junius degeneration
2.7
13.0
92
360
25008
ICD-8 Finland
Diabetes mellitus, Complicatio alia definita
28.6
13.0
17
6
I25.1
ICD-10 Finland
Atherosclerotic heart disease
1.7
12.9
346
2311
L04AX01
ATC
azathioprine; systemic
3.1
12.9
71
238
S05.6
ICD-10 Finland
Penetrating wound of eyeball without foreign body
50.5
12.9
15
*
M86.9
ICD-10 Finland
Osteomyelitis, unspecified
9.1
12.7
26
29
H15.1
ICD-10 Finland
Episcleritis
5.7
12.7
36
65
PF1BT
NOMESCO Finland
Extensive PTA of arteries of knee, lower leg and ankle
15.6
12.6
20
13
36400
ICD-8 Finland
Iritis, Iridocyclitis acuta
12.4
12.6
22
18
I79.2*E10.5
ICD-10 Finland
Insulin-dependent diabetes mellitus - Diabetic peripheral angiopathy
70.5
12.6
14
*
H221, M084
ICD-10 Finland
NA
+∞
12.5
12
*
N083, E102
ICD-10 Finland
NA
+∞
12.5
12
*
R2120
NOMESCO Finland
Counselling and guidance concerning rehabilitation services and social security
8.8
12.5
26
30
A10AB06
ATC
insulin glulisine; parenteral
9.4
12.5
25
27
H22.1
ICD-10 Finland
Iridocyclitis in other diseases classified elsewhere
131.1
12.5
13
*
NK4XE
NOMESCO Finland
Joint ultrasound examination not elsewhere classified
2.6
12.4
92
369
L04AA13
ATC
leflunomide; oral
4.2
12.4
46
112
F93
ICPC
Glaucoma
11.7
12.3
22
19
R2130
NOMESCO Finland
Counselling and guidance which enhance independent living
2.3
12.2
116
530
S05.0
ICD-10 Finland
Injury of conjunctiva and corneal abrasion without mention of foreign body
4.7
12.0
40
87
H44.0
ICD-10 Finland
Purulent endophthalmitis
47.1
11.9
14
*
CJF20
NOMESCO Finland
Removal of artificial lens
47.1
11.9
14
*
25002
ICD-8 Finland
Diabetes mellitus, Retinopathia diabetica
47.1
11.9
14
*
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
1.8
11.9
242
1489
CKW99
NOMESCO Finland
Other operation on choroid, vitreous body and retina
11.8
11.8
21
18
O24.0
ICD-10 Finland
Diabetes mellitus in pregnancy: Pre-existing diabetes mellitus, insulin-dependent
8.5
11.8
25
30
H54.7
ICD-10 Finland
Unspecified visual loss
8.5
11.8
25
30
N25.8
ICD-10 Finland
Other disorders resulting from impaired renal tubular function
14.8
11.8
19
13
L88
ICPC
Rheumatoid/seropositive arthritis
3.2
11.8
61
196
CHD35
NOMESCO Finland
Laser goniopuncture
10.6
11.8
22
21
I50.9
ICD-10 Finland
Heart failure, unspecified
1.8
11.7
232
1416
2507B
ICD-9 Finland
Diabetes mellitus, Diabetes with peripheral circulatory disorders[DIABETES MELLITUS CUM COMPLICAT ALIA ,TYYPPI I]
30.3
11.6
15
5
H02.4
ICD-10 Finland
Ptosis of eyelid
3.7
11.6
50
139
CJF10
NOMESCO Finland
Secondary implantation of artificial lens in posterior chamber
65.5
11.6
13
*
CJF45
NOMESCO Finland
Removal and implantation of artificial lens in anterior chamber with iridectomy or iridotomy
19.1
11.6
17
9
S01BA09
ATC
clobetasone; ophthalmic
19.1
11.6
17
9
3640A
ICD-9 Finland
Disorders of iris and ciliary body, Acute and subacute iridocyclitis
19.1
11.6
17
9
E11.6
ICD-10 Finland
Type 2 diabetes mellitus, with other specified complications
5.0
11.6
36
73
A02BC02
ATC
pantoprazole; systemic
1.5
11.6
821
6827
37403
ICD-8 Finland
Cataract, Complicata
23.1
11.6
16
7
H05BX01
ATC
cinacalcet; oral
11.2
11.5
21
19
A10BA02
ATC
metformin; oral
1.6
11.5
360
2492
3718X
ICD-9 Finland
Corneal opacity and other disorders of cornea, Other corneal disorders
+∞
11.5
11
*
CL2L4
NOMESCO Finland
Wide-field fundus photography for diabetic retinopathy screening
+∞
11.5
11
*
M14.6
ICD-10 Finland
Neuropathic arthropathy
+∞
11.5
11
*
H35.29
ICD-10 Finland
Other proliferative retinopathy
120.9
11.4
12
*
CHC00
NOMESCO Finland
Iridotomy
120.9
11.4
12
*
CGG60
NOMESCO Finland
Reinforcement of sclera using graft
120.9
11.4
12
*
CDC10
NOMESCO Finland
Enucleation of eye with insertion of prosthesis
120.9
11.4
12
*
CG2S4
NOMESCO Finland
Photography of cornea
11.9
11.3
20
17
CHB15
NOMESCO Finland
Puncture of anterior chamber of eye with replacement of aqueous
35.3
11.3
14
*
NK6QA
NOMESCO Finland
Measurement of bone density from tow or more locations with X-ray
2.5
11.3
86
353
Z71.3
ICD-10 Finland
Dietary counselling and surveillance
2.8
11.3
70
254
SPAT1225
SPAT
Implementation of podiatry rehabilitation plan
3.6
11.2
50
144
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
1.8
11.1
193
1126
L04AD01
ATC
ciclosporin; systemic
4.3
11.1
40
95
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
2.3
11.1
102
462
N02BE01
ATC
paracetamol; systemic, rectal
1.6
11.0
1112
9926
F01
ICPC
Eye pain
3.9
11.0
44
115
CHB99
NOMESCO Finland
Other operation on anterior chamber and anterior chamber angle
43.7
10.9
13
*
3792A
ICD-9 Finland
Other disorders of eye, Disorders of vitreous body
43.7
10.9
13
*
H01.0
ICD-10 Finland
Blepharitis
2.7
10.8
75
289
37872
ICD-8 Finland
Other diseases of eye, Aphakia artefacta, acquisita
15.6
10.8
17
11
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
1.7
10.8
232
1446
C08CA13
ATC
lercanidipine; oral
1.8
10.7
182
1053
B03XA01
ATC
erythropoietin; parenteral
6.4
10.6
27
43
3719
FHL
Other measure in this category
60.4
10.6
12
*
CGG99
NOMESCO Finland
Other reconstructive operations on cornea and sclera
60.4
10.6
12
*
H40.11
ICD-10 Finland
Low pressure glaucoma
3.8
10.6
44
119
A10BB12
ATC
glimepiride; oral
2.2
10.6
113
546
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
2.0
10.6
130
666
H35.38
ICD-10 Finland
Preretinal fibrosis of the macula
3.3
10.6
53
167
PD4BC
NOMESCO Finland
Extensive arterigography of lower extremity with X-ray
4.9
10.5
33
68
R1220
NOMESCO Finland
Psychological examination of need and possibilities to rehabilitation
9.2
10.5
21
23
B03XA03
ATC
methoxy polyethylene glycol-epoetin beta; parenteral
9.2
10.5
21
23
H44.4
ICD-10 Finland
Hypotony of eye
110.8
10.4
11
*
Q15.0
ICD-10 Finland
Congenital glaucoma
110.8
10.4
11
*
RJ120
NOMESCO Finland
NA
110.8
10.4
11
*
36409
ICD-8 Finland
Iritis, Unspecified
110.8
10.4
11
*
H22.1*D86.8
ICD-10 Finland
Iridocyclitis in sarcoidosis
110.8
10.4
11
*
N0830, E102
ICD-10 Finland
NA
110.8
10.4
11
*
T85.3
ICD-10 Finland
Mechanical complication of other ocular prosthetic devices, implants and grafts
+∞
10.4
10
*
3747
FHL
Combined ablation and vitreous surgery with coagulation
+∞
10.4
10
*
CWW99
NOMESCO Finland
Other reoperation on eye and adjacent structures
+∞
10.4
10
*
JLE03
NOMESCO Finland
Allogenic total transplantation of pancreas with pancreaticoenterostomy
+∞
10.4
10
*
C10AA05
ATC
atorvastatin; oral
1.5
10.4
484
3658
SPAT1263
SPAT
Sampling
1.5
10.4
526
4046
E16.0
ICD-10 Finland
Drug-induced hypoglycaemia without coma
16.2
10.4
16
10
PF1AT
NOMESCO Finland
Intravascular dilatation of arteries of knee, lower leg and ankle (PTA)
6.4
10.3
26
41
H10.9
ICD-10 Finland
Conjunctivitis, unspecified
2.7
10.3
68
255
S01AA01
ATC
chloramphenicol; ophthalmic (antibiotics)
2.4
10.3
83
352
PG5RT
NOMESCO Finland
PTA of arterio-venous shunt for dialysis
18.9
10.3
15
8
L04AA11
ATC
[U] etanercept; parenteral
18.9
10.3
15
8
J01DB01
ATC
cefalexin; oral
1.5
10.3
1034
9128
4AA12
NOMESCO Finland
NA
23.5
10.2
14
6
S01KA02
ATC
hypromellose; ophthalmic
4.2
10.2
37
89
SPAT1156
SPAT
Guidance concerning treatment of rash and skin
1.8
10.2
191
1140
JAK10
NOMESCO Finland
Laparotomy and insertion of peritoneal dialysis catheter
10.1
10.0
19
19
H11.3
ICD-10 Finland
Conjunctival haemorrhage
2.9
10.0
60
215
CHW99
NOMESCO Finland
Other operation on anterior chamber, anterior chamber angle, iris or ciliary body
40.3
10.0
12
*
T86.8
ICD-10 Finland
Failure and rejection of other transplanted organs and tissues
40.3
10.0
12
*
CKC65
NOMESCO Finland
Removal of buckling implant from sclera
40.3
10.0
12
*
71200
ICD-8 Finland
Rheumatoid arthritis and allied conditions, Juvenile rheumatoid arthritis
40.3
10.0
12
*
CGF10
NOMESCO Finland
Suture of laceration of cornea
40.3
10.0
12
*
QDB05
NOMESCO Finland
Revision of wound of skin of lower limb
3.7
9.9
42
116
C07AB07
ATC
bisoprolol; oral
1.4
9.8
619
4962
NGQ20
NOMESCO Finland
Amputation of lower leg
8.2
9.8
21
26
WZB00
NOMESCO Finland
Telephone receipt or other advice
1.6
9.8
322
2245
WX110
NOMESCO Finland
Local anesthesy
1.4
9.8
808
6815
SPAT1301
SPAT
No procedures
1.5
9.8
402
2950
I50.0
ICD-10 Finland
Congestive heart failure
2.0
9.7
128
676
TPH90
NOMESCO Finland
Removal of fixed intravenous catheter
5.2
9.7
29
57
3651A
ICD-9 Finland
Glaucoma, Open-angle glaucoma[GLAUCOMA SIMPLEX (AVOKULMA)]
7.4
9.7
22
30
PBL09
NOMESCO Finland
Construction of arteriovenous fistula from brachial artery
13.5
9.7
16
12
8720/3-C69.3
ICD-O-3
Malignant melanoma, NOS, of choroid
55.4
9.7
11
*
CK9F4
NOMESCO Finland
Fluorescein angiography (FAG) of choroid and retina
9.2
9.5
19
21
CDC40
NOMESCO Finland
Evisceration of eye with insertion of prosthesis
100.7
9.4
10
*
TCH12
NOMESCO Finland
Sample aspiration from anterior chambre
100.7
9.4
10
*
Z97.0
ICD-10 Finland
Presence of artificial eye
100.7
9.4
10
*
H28.0
ICD-10 Finland
Diabetic cataract
100.7
9.4
10
*
H3603, H405
ICD-10 Finland
NA
+∞
9.4
9
*
A41.0
ICD-10 Finland
Sepsis due to Staphylococcus aureus
3.6
9.4
40
112
H30.9
ICD-10 Finland
Chorioretinal inflammation, unspecified
21.8
9.4
13
6
L28
ICPC
Limited function/disability (L)
1.7
9.3
223
1431
H18.4
ICD-10 Finland
Corneal degeneration
9.6
9.3
18
19
R06.0
ICD-10 Finland
Dyspnoea
1.5
9.2
310
2171
R4160
NOMESCO Finland
Other therapy enhancing rehabilitation
3.9
9.1
36
94
H40.12
ICD-10 Finland
Pigmentary glaucoma
11.5
9.1
16
14
L98.4
ICD-10 Finland
Chronic ulcer of skin, not elsewhere classified
4.0
9.1
35
90
CFB00
NOMESCO Finland
Suture of conjunctiva
15.7
9.0
14
9
M65.3
ICD-10 Finland
Trigger finger
2.9
9.0
53
188
CHD10
NOMESCO Finland
Trabeculectomy
24.2
8.9
12
5
A46
ICD-10 Finland
Erysipelas
1.7
8.9
183
1126
N03AX16
ATC
pregabalin; oral
1.6
8.8
273
1873
H10.0
ICD-10 Finland
Mucopurulent conjunctivitis
2.4
8.8
70
295
F32.9
ICD-10 Finland
Depressive episode, unspecified
1.9
8.8
130
716
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
1.5
8.7
398
2976
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.5
8.7
359
2626
H17.8
ICD-10 Finland
Other corneal scars and opacities
14.1
8.7
14
10
74439
ICD-8 Finland
Congenital anomalies of eye, Cataracta NUD
50.3
8.7
10
*
SPAT1249
SPAT
Treatment-related counselling outside office
1.4
8.7
460
3541
RS221
NOMESCO Finland
NA
5.1
8.7
26
52
ZZA00
NOMESCO Finland
Split skin graft
2.9
8.6
50
175
O80.0
ICD-10 Finland
Spontaneous vertex delivery
0.4
8.6
45
992
F28
ICPC
Limited function/disability (F)
6.2
8.6
22
36
M46.1
ICD-10 Finland
Sacroiliitis, not elsewhere classified
5.5
8.6
24
44
S01FB01
ATC
phenylephrine; ophthalmic (sympathomimetics excl. antiglaucoma prep.)
27.7
8.5
11
*
S01GX01
ATC
cromoglicic acid; ophthalmic
1.6
8.4
208
1343
H221, M083
ICD-10 Finland
NA
90.6
8.4
9
*
3604
FHL
Penetration of the cornea
90.6
8.4
9
*
E16.2
ICD-10 Finland
Hypoglycaemia, unspecified
4.9
8.4
26
54
N08.32
ICD-10 Finland
Glomerular disorders in diabetes mellitus kidney failure
+∞
8.3
8
*
H3603, H431
ICD-10 Finland
NA
+∞
8.3
8
*
R4180
NOMESCO Finland
Podiatric therapy
6.3
8.3
21
34
H18.5
ICD-10 Finland
Hereditary corneal dystrophies
5.9
8.3
22
38
TPX10
NOMESCO Finland
Implantation of vascular injection port
3.0
8.3
47
161
PE1AT
NOMESCO Finland
Femoral artery PTA
4.8
8.3
26
55
A41.9
ICD-10 Finland
Sepsis, unspecified
2.6
8.2
60
241
R4110
NOMESCO Finland
Physiotherapy
1.5
8.2
323
2337
WX213
NOMESCO Finland
Lower leg blockade
7.6
8.2
18
24
L84
ICD-10 Finland
Corns and callosities
2.7
8.1
52
195
H17.1
ICD-10 Finland
Other central corneal opacity
33.5
8.1
10
*
H16.1
ICD-10 Finland
Other superficial keratitis without conjunctivitis
11.8
8.1
14
12
H35.36
ICD-10 Finland
Macular cyst
6.9
8.1
19
28
F99
ICPC
Eye/adnexa disease other
6.9
8.1
19
28
TQW11
NOMESCO Finland
Vacuum treatment of wound
3.9
8.1
31
80
C10AX09
ATC
ezetimibe; oral
1.9
8.0
126
709
CF2S4
NOMESCO Finland
Photography of conjunctiva
22.1
8.0
11
5
TNX92
NOMESCO Finland
Supporting bandage or orthosis of lower limb
4.1
8.0
29
71
G63.2*E11.4
ICD-10 Finland
Non-insulin-dependent diabetes mellitus - Diabetic polyneuropathy
5.6
8.0
22
40
SPAT1310
SPAT
Counselling related to known health issue
1.5
8.0
364
2715
H54.5
ICD-10 Finland
Severe visual impairment, monocular
7.8
7.9
17
22
PG1DE
NOMESCO Finland
Other extensive ultrasound examination of artery
2.5
7.8
60
247
WX000
NOMESCO Finland
Monitoring vital functions without anesthesy
2.6
7.8
55
219
R11
ICD-10 Finland
Nausea and vomiting
1.9
7.7
103
548
D86.8
ICD-10 Finland
Sarcoidosis of other and combined sites
6.4
7.7
19
30
M86.6
ICD-10 Finland
Other chronic osteomyelitis
15.1
7.7
12
8
CKA10
NOMESCO Finland
Biopsy of vitreous body
15.1
7.7
12
8
S05.2
ICD-10 Finland
Ocular laceration and rupture with prolapse or loss of intraocular tissue
45.2
7.7
9
*
CK2K4
NOMESCO Finland
Red-free imaging of ocular fundus
45.2
7.7
9
*
PD4CC
NOMESCO Finland
Very extensive arterigography of lower extremity with X-ray
7.5
7.7
17
23
RD210
NOMESCO Finland
NA
3.9
7.7
30
79
Y83
ICD-10 Finland
Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
2.0
7.6
98
513
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
2.1
7.6
83
407
Q12.0
ICD-10 Finland
Congenital cataract
18.5
7.6
11
6
CK2M4
NOMESCO Finland
Macular light layer imaging (OCT)
18.5
7.6
11
6
CH2S4
NOMESCO Finland
Photography of iris
18.5
7.6
11
6
QDA10
NOMESCO Finland
Incision of skin of lower limb
8.1
7.6
16
20
J18.9
ICD-10 Finland
Pneumonia, unspecified
1.5
7.6
343
2548
CJE15
NOMESCO Finland
Phakoemulsification with implantation of artificial lens in anterior chamber and iridectomy or iridotomy
5.0
7.6
23
47
C09CA01
ATC
losartan; oral
1.5
7.6
298
2150
M14.6*A52.1
ICD-10 Finland
Charcot's or tabetic arthropathy
25.1
7.6
10
*
B00.5
ICD-10 Finland
Herpesviral ocular disease
25.1
7.6
10
*
M75.0
ICD-10 Finland
Adhesive capsulitis of shoulder
2.4
7.6
63
274
A10AD04
ATC
insulin lispro; parenteral (insulins and analog. for injection, intermediate- or long-acting comb. with fast-acting)
10.1
7.5
14
14
N17.9
ICD-10 Finland
Acute renal failure, unspecified
2.4
7.5
59
248
C09BA02
ATC
enalapril and diuretics; systemic
1.9
7.5
118
663
I20.81
ICD-10 Finland
Other angina pectoris stenosed coronary artery
1.8
7.5
125
721
H21.9
ICD-10 Finland
Disorder of iris and ciliary body, unspecified
80.5
7.4
8
*
C69.39
ICD-10 Finland
Malignant tumor in chorioidea other or unspecified histology
80.5
7.4
8
*
L04AB06
ATC
golimumab; parenteral
7.7
7.4
16
21
C01DA08
ATC
isosorbide dinitrate; oral, oral aerosol, sublingual, transdermal
1.5
7.4
320
2355
H43.3
ICD-10 Finland
Other vitreous opacities
4.8
7.3
23
49
SPAT1254
SPAT
Administration of medicine
1.6
7.3
197
1303
FN1BC
NOMESCO Finland
Extensive angiography of hear and/or coronary arteries
2.1
7.3
76
366
H16.3
ICD-10 Finland
Interstitial and deep keratitis
+∞
7.3
7
*
CKD30
NOMESCO Finland
Internal drainage of subretinal fluid
+∞
7.3
7
*
CJB99
NOMESCO Finland
Other operation on lens for secondary cataract
+∞
7.3
7
*
C69.42
ICD-10 Finland
Malignant tumor of ciliary melanoma
+∞
7.3
7
*
7433A
ICD-9 Finland
Congenital anomalies of eye, Congenital cataract and lens anomalies
+∞
7.3
7
*
H360, E103
ICD-10 Finland
NA
+∞
7.3
7
*
3624
FHL
Extracapsular soft cataract removal
+∞
7.3
7
*
3656E
ICD-9 Finland
Glaucoma associated with other ocular disorders[GLAUCOMA POSTTRAUMATICUM]
+∞
7.3
7
*
H3603, E119
ICD-10 Finland
NA
+∞
7.3
7
*
ZZL00
NOMESCO Finland
Free graft of amniotic membrane
+∞
7.3
7
*
3619
FHL
Other operations in this group, such as corneal refractive surgery
+∞
7.3
7
*
RJ410
NOMESCO Finland
NA
9.4
7.3
14
15
SPAT1216
SPAT
Assessment of functional ability
1.6
7.2
209
1403
S01BC01
ATC
indometacin; ophthalmic
15.8
7.2
11
7
XCD00
NOMESCO Finland
Clinical examination of eye in general anaesthesia
30.2
7.1
9
*
285
Kela drug reimbursment
Dulaglutide, exenatide, liraglutide, lixisenatide and semaglutide (adults)
2.5
7.1
53
216
H44.2
ICD-10 Finland
Degenerative myopia
20.1
7.1
10
5
NDG30
NOMESCO Finland
Fusion of wrist, total
8.0
7.1
15
19
H53.9
ICD-10 Finland
Visual disturbance, unspecified
2.9
7.1
41
144
L02.2
ICD-10 Finland
Cutaneous abscess, furuncle and carbuncle of trunk
2.6
7.1
50
199
WZC00
NOMESCO Finland
Planning of intervention or health care consultation
1.4
7.1
375
2867
160
Kela drug reimbursment
exenatide
3.9
7.1
27
70
P01BA02
ATC
hydroxychloroquine; oral
1.9
7.1
94
501
N03AX12
ATC
gabapentin; oral
1.6
7.1
175
1131
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
1.9
7.1
107
596
I79.2*E11.5
ICD-10 Finland
Non-insulin-dependent diabetes mellitus - Diabetic peripheral angiopathy
10.1
7.0
13
13
RJ420
NOMESCO Finland
NA
10.1
7.0
13
13
E0000UV
ATC
NA
1.4
7.0
457
3621
J01CF05
ATC
flucloxacillin; systemic
2.5
7.0
53
220
N19
ICD-10 Finland
Unspecified kidney failure
2.5
7.0
53
220
CBJ40
NOMESCO Finland
Resection of levator muscle of eyelid
7.0
7.0
16
23
W44
ICD-10 Finland
Foreign body entering into or through eye or natural orifice
3.9
7.0
27
71
A10BH05
ATC
linagliptin; oral
2.2
6.9
67
314
E11.1
ICD-10 Finland
Type 2 diabetes mellitus, with ketoacidosis
7.6
6.9
15
20
3744
FHL
Pericardial identification surgery with coagulation (includes epi- and intrascleral indications and eg Lincoff catheter)
13.8
6.9
11
8
RJ521
NOMESCO Finland
NA
13.8
6.9
11
8
PG5DE
NOMESCO Finland
Ultrasound examination of injection gate to artery or vein with Doppler method
13.8
6.9
11
8
H15.0
ICD-10 Finland
Scleritis
13.8
6.9
11
8
TPH07
NOMESCO Finland
Cathetrisation of artery
1.7
6.9
130
779
C09AA05
ATC
ramipril; oral
1.4
6.8
318
2371
TK810
NOMESCO Finland
Hemofiltration
6.7
6.8
16
24
CD2S4
NOMESCO Finland
Photography of eye
6.7
6.8
16
24
L03.0
ICD-10 Finland
Cellulitis of finger and toe
2.0
6.8
84
436
F43
ICPC
Eye, Other diagnostic procedure
3.7
6.8
27
73
CGF45
NOMESCO Finland
Suture of laceration of sclera
40.2
6.8
8
*
CJE00
NOMESCO Finland
Phakoemulsification
40.2
6.8
8
*
Z96.4
ICD-10 Finland
Presence of endocrine implants
40.2
6.8
8
*
C69.3
ICD-10 Finland
Malignant neoplasm: Choroid
16.8
6.7
10
6
H16.2
ICD-10 Finland
Keratoconjunctivitis
7.2
6.7
15
21
A12AA12
ATC
[U] calcium acetate anhydrous; systemic
22.6
6.7
9
*
H40.29
ICD-10 Finland
Other [primary] glaucoma with closed ventricular angle
22.6
6.7
9
*
RJ210
NOMESCO Finland
NA
22.6
6.7
9
*
FN1AC
NOMESCO Finland
Angiography of heart and/or coronary arteries
1.5
6.6
276
2011
R42
ICD-10 Finland
Dizziness and giddiness
1.5
6.6
272
1976
H53.1
ICD-10 Finland
Subjective visual disturbances
2.1
6.6
73
359
H19.1
ICD-10 Finland
Herpesviral keratitis and keratoconjunctivitis
12.3
6.6
11
9
Z94.8
ICD-10 Finland
Other transplanted organ and tissue status
8.7
6.6
13
15
G63.2
ICD-10 Finland
Diabetic polyneuropathy
8.7
6.6
13
15
NA6AA
NOMESCO Finland
Sacro-iliac joint X-ray examination
10.1
6.5
12
12
I25.2
ICD-10 Finland
Old myocardial infarction
1.8
6.5
115
674
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.4
6.5
439
3494
M01CB01
ATC
sodium aurothiomalate; parenteral
3.7
6.5
26
71
Y83.1
ICD-10 Finland
Surgical operation with implant of artificial internal device as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
3.7
6.5
26
71
SPAT1299
SPAT
Other function in accordance with podiatry nomenclature
3.4
6.4
29
87
J01DA01
ATC
[U] cefalexin; systemic
1.3
6.4
769
6684
H360, E113
ICD-10 Finland
NA
70.1
6.4
7
*
H20.2
ICD-10 Finland
Lens-induced iridocyclitis
70.1
6.4
7
*
CAW99
NOMESCO Finland
Other operation on orbit
70.1
6.4
7
*
37100
ICD-8 Finland
Corneal opacity, Cicatrix (nubecula, macula, leucoma) cornea
70.1
6.4
7
*
NH3AA
NOMESCO Finland
Foot and toes X-ray examination
1.9
6.4
91
498
E11.4
ICD-10 Finland
Type 2 diabetes mellitus, with neurological complications
3.0
6.4
34
115
CBJ30
NOMESCO Finland
Plastic repair of levator aponeurosis of eyelid
7.4
6.4
14
19
SPAT1325
SPAT
Vaccination
1.4
6.4
419
3314
TNH33
NOMESCO Finland
Custom moulded brace, ankle or foot
4.1
6.4
23
57
M05.8
ICD-10 Finland
Other seropositive rheumatoid arthritis
2.0
6.4
74
374
SPAT1144
SPAT
Treatment of reopened or infected surgical wound
1.9
6.4
92
503
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
1.7
6.4
119
712
S20
ICPC
Corn/callosity
3.2
6.4
31
99
NH1AA
NOMESCO Finland
Ankle X-ray examination without contrast
2.1
6.3
71
352
PA6BD
NOMESCO Finland
Extensive CT of neck arteries
2.3
6.3
57
259
N02AA05
ATC
oxycodone; systemic
1.5
6.3
192
1308
PD4CG
NOMESCO Finland
Extensive MRI examination of abdominal aortta and vasculature of lower extremities with high intensity magnet
4.0
6.3
23
58
3650A
ICD-9 Finland
Glaucoma, Borderline glaucoma [glaucoma suspect][SUSPICIO GLAUCOMATIS (AVOKULMA)]
9.3
6.3
12
13
NH1BG
NOMESCO Finland
Ankle and foot MRI examination with high intensity magnet
4.6
6.3
20
44
RJ414
NOMESCO Finland
NA
18.1
6.3
9
5
CA1AD
NOMESCO Finland
Orbita CT
18.1
6.3
9
5
C69.40
ICD-10 Finland
Malignant tumor of ciliary body without histology
+∞
6.3
6
*
H36.04
ICD-10 Finland
Severe diabetic ophthalmopathy
+∞
6.3
6
*
36401
ICD-8 Finland
Iritis, Iridocyclitis glaucomatosa. Syndroma Posner-Schlossman, heterochromia iridis
+∞
6.3
6
*
3702
FHL
Trabeculotomy
+∞
6.3
6
*
3768
FHL
Eye examination under general anesthesia
+∞
6.3
6
*
H3603, E117
ICD-10 Finland
NA
+∞
6.3
6
*
CWF00
NOMESCO Finland
Reoperation for insufficiency of anastomosis or suture in eye and adjacent structures
+∞
6.3
6
*
I63.9
ICD-10 Finland
Cerebral infarction, unspecified
1.6
6.2
150
964
CGF35
NOMESCO Finland
Repair of cornea using graft
26.8
6.2
8
*
J01MA02
ATC
ciprofloxacin; systemic
1.3
6.2
484
3934
NF1AE
NOMESCO Finland
Hip joint ultrasound examination
2.9
6.2
34
118
Z01.8
ICD-10 Finland
Other specified special examinations
1.5
6.2
244
1756
I25.9
ICD-10 Finland
Chronic ischaemic heart disease, unspecified
1.6
6.2
154
1000
TCC10
NOMESCO Finland
Probing of lacrimal canaliculus/duct
6.3
6.2
15
24
UJF32
NOMESCO Finland
Coloscopy
1.4
6.1
304
2289
H10.1
ICD-10 Finland
Acute atopic conjunctivitis
3.2
6.1
29
91
I69.3
ICD-10 Finland
Sequelae of cerebral infarction
1.7
6.1
110
652
CJ2M4
NOMESCO Finland
Scans and measurement printouts for intraocular lens power calculation
4.0
6.1
22
55
CJD20
NOMESCO Finland
Extracapsular cataract extraction with implantation of artificial lens in posterior chamber
10.1
6.0
11
11
TQW80
NOMESCO Finland
Local dermatologic skincare
2.7
6.0
37
138
L03.1
ICD-10 Finland
Cellulitis of other parts of limb
2.8
6.0
36
132
Mortality – FinRegistry
↥Association
Association between endpoint DM_NEOVASCULAR_GLAUCOMA and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| DM_NEOVASCULAR_GLAUCOMA | 1.487 [1.34, 1.65] | < 0.001 |
| Birth year | 0.992 [0.98, 1.0] | 0.06 |
During the follow-up period (1.1.1998 — 31.12.2019), 2304 out of 5718 females with DM_NEOVASCULAR_GLAUCOMA died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| DM_NEOVASCULAR_GLAUCOMA | 1.544 [1.37, 1.74] | < 0.001 |
| Birth year | 0.989 [0.98, 1.0] | 0.012 |
During the follow-up period (1.1.1998 — 31.12.2019), 2217 out of 5865 males with DM_NEOVASCULAR_GLAUCOMA died.
Mortality risk
Mortality risk for people of age
years, who have DM_NEOVASCULAR_GLAUCOMA.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.122% | 0.325% |
| 5 | 0.783% | 1.768% |
| 10 | 1.893% | 4.415% |
| 15 | 3.686% | 8.414% |
| 20 | 6.273% | 14.365% |
Relationships between endpoints
↥Index endpoint: DM_NEOVASCULAR_GLAUCOMA – Neovascular glaucoma
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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