This is a non-core endpoint: only basic statistics are computed.
See these related core endpoints for full statistics:
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleNone |
520210 |
2. Check conditionsNone |
520210 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
439 |
4. Check minimum number of eventsNone |
439 |
5. Include endpointsNone |
439 |
6. Filter based on genotype QC (FinnGen only) |
439 |
Control definitions (FinnGen only)
- Control exclude
- R18_GENERAL_SYMPTOMS_SIGNS
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF4
- Parent code in ICD-10
- R[5-6]
- Name in latin
- Senilitas
Similar endpoints
↥List of similar endpoints to
Senility
based on the number of shared cases.
Similar with more cases:
- General symptoms and signs
- Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
This endpoint is excluded from FinRegistry analyses (omitted endpoint).
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 439 | 230 | 209 |
| Unadjusted period prevalence (%) | 0.08 | 0.08 | 0.09 |
| Median age at first event (years) | 83.62 | 84.45 | 82.71 |
-FinnGen-
Age distribution of first events
-FinnGen-
Year distribution of first events
-FinnGen-
Cumulative Incidence Function
Not a core endpoint, no data to show.
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 362
- Matched controls
- 3610
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
R54
ICD-10 Finland
Senility
+∞
323.0
362
*
R53
ICD-10 Finland
Malaise and fatigue
18.6
96.1
161
149
R50.9
ICD-10 Finland
Fever, unspecified
16.0
29.8
49
35
R55
ICD-10 Finland
Syncope and collapse
21.8
28.1
41
21
A28
ICPC
Limited function/disability NOS
4.2
26.6
121
386
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
3.0
21.1
171
824
N06AX11
ATC
mirtazapine; oral
3.4
20.3
122
471
R56.8
ICD-10 Finland
Other and unspecified convulsions
110.8
19.7
21
*
R42
ICD-10 Finland
Dizziness and giddiness
3.3
18.9
116
454
N39.0
ICD-10 Finland
Urinary tract infection, site not specified
3.4
18.4
103
376
R51.80
ICD-10 Finland
Headache
13.5
17.4
30
24
L28
ICPC
Limited function/disability (L)
3.3
15.7
89
323
N06AB04
ATC
citalopram; systemic
2.9
15.0
108
459
N30.0
ICD-10 Finland
Acute cystitis
3.5
14.8
75
249
A04
ICPC
Weakness/tiredness general
3.8
14.8
68
209
J18.9
ICD-10 Finland
Pneumonia, unspecified
2.5
14.0
155
842
E86
ICD-10 Finland
Volume depletion
7.5
12.0
28
40
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
3.3
11.7
64
223
I69.3
ICD-10 Finland
Sequelae of cerebral infarction
3.4
11.3
58
193
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
2.5
11.3
107
524
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
2.9
10.9
72
285
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
2.2
10.8
133
740
N02BE01
ATC
paracetamol; systemic, rectal
2.2
10.8
249
1819
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
2.7
10.2
78
337
R07.4
ICD-10 Finland
Chest pain, unspecified
2.5
10.1
89
415
N06DX01
ATC
memantine; oral
2.9
10.0
67
265
ZXD05
NOMESCO Finland
Urgent procedure
2.3
10.0
114
604
AA1AD
NOMESCO Finland
CT of head and brain
2.5
9.8
85
393
Z29
ICPC
Social problem NOS
11.8
9.6
17
15
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
2.2
9.6
112
601
N05AH04
ATC
quetiapine; oral
3.0
9.4
55
201
N03AX16
ATC
pregabalin; oral
2.7
9.4
68
284
A29
ICPC
General symptom/complaint other
3.2
9.3
49
167
Z03.3
ICD-10 Finland
Observation for suspected nervous system disorder
4.4
9.2
33
81
J01MA02
ATC
ciprofloxacin; systemic
2.1
9.2
148
908
I48
ICD-10 Finland
Atrial fibrillation and flutter
2.1
9.2
141
850
N05AX08
ATC
risperidone; systemic
2.9
9.1
59
230
-69
ICPC
Other reason for encounter NEC
6.4
9.0
23
38
A06AD11
ATC
lactulose; oral
2.2
9.0
118
661
I95.1
ICD-10 Finland
Orthostatic hypotension
5.3
8.8
26
52
N06AB10
ATC
escitalopram; oral
3.0
8.8
53
195
G30.1
ICD-10 Finland
Alzheimer disease with late onset
2.6
8.6
65
277
ZXD10
NOMESCO Finland
Scheduled procedure
2.0
8.3
126
746
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
2.3
8.2
78
378
A23
ICPC
Risk factor NOS
5.3
8.2
24
48
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
4.0
8.2
32
86
N39.9
ICD-10 Finland
Disorder of urinary system, unspecified
7.1
8.2
19
28
C03CA01
ATC
furosemide; systemic
1.9
8.1
192
1345
A49.9
ICD-10 Finland
Bacterial infection, unspecified
2.8
8.0
53
208
P20
ICPC
Memory disturbance
2.5
8.0
67
301
N05BA04
ATC
oxazepam; oral
2.1
8.0
100
548
N02AX02
ATC
tramadol; systemic, rectal
2.0
7.8
136
846
E87.1
ICD-10 Finland
Hypo-osmolality and hyponatraemia
4.6
7.8
26
60
ZXE10
NOMESCO Finland
More than one and less than three hours
2.0
7.7
108
621
S06.0
ICD-10 Finland
Concussion
3.1
7.6
41
142
W19
ICD-10 Finland
Unspecified fall
2.8
7.5
48
186
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
2.4
7.5
69
328
R41.0
ICD-10 Finland
Disorientation, unspecified
4.1
7.4
28
73
I10
ICD-10 Finland
Essential (primary) hypertension
1.8
7.4
202
1468
XFP20
NOMESCO Finland
Check up of cardiac pacemaker
3.5
7.4
33
100
F21
ICPC
NA
11.1
7.3
13
12
F10.24
ICD-10 Finland
Alcohol depence active use
+∞
7.3
7
*
X59
ICD-10 Finland
Exposure to unspecified factor
2.7
7.2
49
197
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
5.5
7.2
20
38
F03
ICD-10 Finland
Unspecified dementia
2.3
7.0
64
302
R60.0
ICD-10 Finland
Localized oedema
3.2
7.0
35
116
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
2.1
6.9
87
472
C07AB07
ATC
bisoprolol; oral
1.8
6.9
174
1221
B01AA03
ATC
warfarin; systemic
1.9
6.9
122
761
A01
ICPC
Pain general/multiple sites
3.5
6.8
30
90
SPAT1292
SPAT
Other function in accordance with SHToL (Finnish classification of nursing interventions)
2.9
6.8
40
148
S20.2
ICD-10 Finland
Contusion of thorax
4.4
6.7
23
55
N02AA05
ATC
oxycodone; systemic
2.3
6.7
64
307
J01DB01
ATC
cefalexin; oral
1.8
6.6
199
1471
Z71.8
ICD-10 Finland
Other specified counselling
2.5
6.5
51
222
XF400
NOMESCO Finland
ECG with 12 standard connections
2.2
6.5
71
361
G40.9
ICD-10 Finland
Epilepsy, unspecified
5.9
6.5
17
30
I25.5
ICD-10 Finland
Ischaemic cardiomyopathy
4.8
6.5
20
43
I50.9
ICD-10 Finland
Heart failure, unspecified
1.9
6.5
107
645
I63.9
ICD-10 Finland
Cerebral infarction, unspecified
2.2
6.4
69
352
K90
ICPC
Stroke/cerebrovascular accident
6.1
6.4
16
27
N30.9
ICD-10 Finland
Cystitis, unspecified
3.0
6.3
36
129
C01DA02
ATC
glyceryl trinitrate; oral, oral aerosol, sublingual, transdermal
1.8
6.2
161
1129
R41.8
ICD-10 Finland
Other and unspecified symptoms and signs involving cognitive functions and awareness
2.6
6.2
43
176
U28
ICPC
Limited function/disability (U)
10.2
6.1
11
11
ZXA00
NOMESCO Finland
Right side
1.9
6.0
93
547
F32.9
ICD-10 Finland
Depressive episode, unspecified
3.3
6.0
29
94
Mortality – FinRegistry
↥This endpoint is excluded from FinRegistry analyses (omitted endpoint).
Relationships between endpoints
↥Index endpoint: R18_SENILITY – Senility
GWS hits: -
This endpoint is excluded from FinRegistry analyses (omitted endpoint).