This is a non-core endpoint: only basic statistics are computed.
See these related core endpoints for full statistics:
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleNone |
520210 |
2. Check conditionsNone |
520210 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
439 |
4. Check minimum number of eventsNone |
439 |
5. Include endpointsNone |
439 |
6. Filter based on genotype QC (FinnGen only) |
439 |
Control definitions (FinnGen only)
- Control exclude
- R18_GENERAL_SYMPTOMS_SIGNS
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF4
- Parent code in ICD-10
- R[5-6]
- Name in latin
- Senilitas
Similar endpoints
↥List of similar endpoints to
Senility
based on the number of shared cases.
Similar with more cases:
- General symptoms and signs
- Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
This endpoint is excluded from FinRegistry analyses (omitted endpoint).
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 439 | 230 | 209 |
| Unadjusted period prevalence (%) | 0.08 | 0.08 | 0.09 |
| Median age at first event (years) | 83.62 | 84.45 | 82.71 |
-FinnGen-
Age distribution of first events
-FinnGen-
Year distribution of first events
-FinnGen-
Cumulative Incidence Function
Not a core endpoint, no data to show.
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 362
- Matched controls
- 3610
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
R54
ICD-10 Finland
Senility
+∞
323.0
362
*
R53
ICD-10 Finland
Malaise and fatigue
18.6
96.1
161
149
R50.9
ICD-10 Finland
Fever, unspecified
16.0
29.8
49
35
R55
ICD-10 Finland
Syncope and collapse
21.8
28.1
41
21
A28
ICPC
Limited function/disability NOS
4.2
26.6
121
386
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
3.0
21.1
171
824
N06AX11
ATC
mirtazapine; oral
3.4
20.3
122
471
R56.8
ICD-10 Finland
Other and unspecified convulsions
110.8
19.7
21
*
R42
ICD-10 Finland
Dizziness and giddiness
3.3
18.9
116
454
N39.0
ICD-10 Finland
Urinary tract infection, site not specified
3.4
18.4
103
376
R51.80
ICD-10 Finland
Headache
13.5
17.4
30
24
L28
ICPC
Limited function/disability (L)
3.3
15.7
89
323
N06AB04
ATC
citalopram; systemic
2.9
15.0
108
459
N30.0
ICD-10 Finland
Acute cystitis
3.5
14.8
75
249
A04
ICPC
Weakness/tiredness general
3.8
14.8
68
209
J18.9
ICD-10 Finland
Pneumonia, unspecified
2.5
14.0
155
842
E86
ICD-10 Finland
Volume depletion
7.5
12.0
28
40
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
3.3
11.7
64
223
I69.3
ICD-10 Finland
Sequelae of cerebral infarction
3.4
11.3
58
193
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
2.5
11.3
107
524
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
2.9
10.9
72
285
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
2.2
10.8
133
740
N02BE01
ATC
paracetamol; systemic, rectal
2.2
10.8
249
1819
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
2.7
10.2
78
337
R07.4
ICD-10 Finland
Chest pain, unspecified
2.5
10.1
89
415
N06DX01
ATC
memantine; oral
2.9
10.0
67
265
AA1AD
NOMESCO Finland
CT of head and brain
2.5
9.8
85
393
Z29
ICPC
Social problem NOS
11.8
9.6
17
15
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
2.2
9.6
112
601
N05AH04
ATC
quetiapine; oral
3.0
9.4
55
201
N03AX16
ATC
pregabalin; oral
2.7
9.4
68
284
A29
ICPC
General symptom/complaint other
3.2
9.3
49
167
Z03.3
ICD-10 Finland
Observation for suspected nervous system disorder
4.4
9.2
33
81
J01MA02
ATC
ciprofloxacin; systemic
2.1
9.2
148
908
I48
ICD-10 Finland
Atrial fibrillation and flutter
2.1
9.2
141
850
N05AX08
ATC
risperidone; systemic
2.9
9.1
59
230
-69
ICPC
Other reason for encounter NEC
6.4
9.0
23
38
A06AD11
ATC
lactulose; oral
2.2
9.0
118
661
I95.1
ICD-10 Finland
Orthostatic hypotension
5.3
8.8
26
52
N06AB10
ATC
escitalopram; oral
3.0
8.8
53
195
G30.1
ICD-10 Finland
Alzheimer disease with late onset
2.6
8.6
65
277
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
2.3
8.2
78
378
A23
ICPC
Risk factor NOS
5.3
8.2
24
48
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
4.0
8.2
32
86
N39.9
ICD-10 Finland
Disorder of urinary system, unspecified
7.1
8.2
19
28
C03CA01
ATC
furosemide; systemic
1.9
8.1
192
1345
A49.9
ICD-10 Finland
Bacterial infection, unspecified
2.8
8.0
53
208
P20
ICPC
Memory disturbance
2.5
8.0
67
301
N05BA04
ATC
oxazepam; oral
2.1
8.0
100
548
N02AX02
ATC
tramadol; systemic, rectal
2.0
7.8
136
846
E87.1
ICD-10 Finland
Hypo-osmolality and hyponatraemia
4.6
7.8
26
60
S06.0
ICD-10 Finland
Concussion
3.1
7.6
41
142
W19
ICD-10 Finland
Unspecified fall
2.8
7.5
48
186
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
2.4
7.5
69
328
R41.0
ICD-10 Finland
Disorientation, unspecified
4.1
7.4
28
73
I10
ICD-10 Finland
Essential (primary) hypertension
1.8
7.4
202
1468
XFP20
NOMESCO Finland
Check up of cardiac pacemaker
3.5
7.4
33
100
F21
ICPC
NA
11.1
7.3
13
12
F10.24
ICD-10 Finland
Alcohol depence active use
+∞
7.3
7
*
X59
ICD-10 Finland
Exposure to unspecified factor
2.7
7.2
49
197
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
5.5
7.2
20
38
F03
ICD-10 Finland
Unspecified dementia
2.3
7.0
64
302
R60.0
ICD-10 Finland
Localized oedema
3.2
7.0
35
116
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
2.1
6.9
87
472
C07AB07
ATC
bisoprolol; oral
1.8
6.9
174
1221
B01AA03
ATC
warfarin; systemic
1.9
6.9
122
761
A01
ICPC
Pain general/multiple sites
3.5
6.8
30
90
SPAT1292
SPAT
Other function in accordance with SHToL (Finnish classification of nursing interventions)
2.9
6.8
40
148
S20.2
ICD-10 Finland
Contusion of thorax
4.4
6.7
23
55
N02AA05
ATC
oxycodone; systemic
2.3
6.7
64
307
J01DB01
ATC
cefalexin; oral
1.8
6.6
199
1471
Z71.8
ICD-10 Finland
Other specified counselling
2.5
6.5
51
222
XF400
NOMESCO Finland
ECG with 12 standard connections
2.2
6.5
71
361
G40.9
ICD-10 Finland
Epilepsy, unspecified
5.9
6.5
17
30
I25.5
ICD-10 Finland
Ischaemic cardiomyopathy
4.8
6.5
20
43
I50.9
ICD-10 Finland
Heart failure, unspecified
1.9
6.5
107
645
I63.9
ICD-10 Finland
Cerebral infarction, unspecified
2.2
6.4
69
352
K90
ICPC
Stroke/cerebrovascular accident
6.1
6.4
16
27
N30.9
ICD-10 Finland
Cystitis, unspecified
3.0
6.3
36
129
C01DA02
ATC
glyceryl trinitrate; oral, oral aerosol, sublingual, transdermal
1.8
6.2
161
1129
R41.8
ICD-10 Finland
Other and unspecified symptoms and signs involving cognitive functions and awareness
2.6
6.2
43
176
U28
ICPC
Limited function/disability (U)
10.2
6.1
11
11
ZXA00
NOMESCO Finland
Right side
1.9
6.0
93
547
F32.9
ICD-10 Finland
Depressive episode, unspecified
3.3
6.0
29
94
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
73
187
4.47
26.50
3.0
3.5
1.5
1.5
mmol/l
0.14
67
174
57
128
4.95
24.26
2.0
1.4
—
—
—
0
0
82
250
3.79
23.36
1.9
1.5
—
—
—
0
0
100
371
3.18
20.81
31.3
35.2
1.0
1.7
inr
—
5
37
79
253
3.58
20.80
1.9
1.5
—
—
—
0
0
164
796
2.68
20.76
2.2
2.1
76.0
80.0
nmol/l
0.91
151
668
99
377
3.09
19.62
2.0
1.5
—
—
—
0
0
54
139
4.28
19.30
2.0
1.5
—
—
—
0
0
60
170
3.92
18.82
1.6
2.0
0.2
0.2
g/l
0.56
47
154
132
615
2.63
17.73
4.3
3.0
0.4
0.7
e6/l
1.31
108
474
85
314
3.11
17.63
4.0
2.8
2.7
2.4
e6/l
0.11
57
172
87
336
2.97
16.64
1.9
2.1
9.3
11.5
umol/l
2.47
80
303
154
793
2.44
16.57
4.2
3.1
—
—
—
0
0
192
1097
2.32
16.22
4.9
4.8
1.2
1.2
mmol/l
0.28
172
882
178
997
2.31
15.63
2.5
2.0
85.5
89.8
pmol/l
0.69
104
503
129
632
2.47
15.31
2.7
1.9
185.0
441.7
u/l
1.21
121
582
99
438
2.62
14.48
6.5
3.5
83.4
358.8
ng/l
1.48
93
396
70
260
3.00
14.24
2.2
2.2
0.8
0.8
mmol/l
0.79
63
237
73
278
2.94
14.21
1.9
2.2
17.6
20.2
%
0.73
68
230
179
1037
2.22
14.19
6.8
6.0
4.9
4.4
e9/l
1.52
156
880
81
327
2.80
14.15
3.7
2.7
0.8
1.3
e6/l
1.34
53
184
168
954
2.22
13.94
3.6
3.7
32.2
34.1
g/l
3.05
148
858
170
978
2.20
13.59
5.0
4.2
1.2
1.2
mmol/l
0.09
158
835
120
606
2.34
13.06
2.9
2.1
3.1
3.4
mg/l
0.63
102
503
25
47
5.56
12.86
1.4
1.3
—
—
—
0
0
25
47
5.56
12.86
1.4
1.3
—
—
—
0
0
31
71
4.61
12.77
1.5
1.9
224.2
1218.7
ug/l
0.88
26
65
195
1212
2.09
12.51
4.9
3.6
6.8
7.0
mmol/l
0.61
186
1105
113
576
2.29
11.91
1.8
1.5
17.5
20.1
nmol/l
1.02
102
469
168
1008
2.07
11.67
5.0
4.5
12.5
13.1
umol/l
0.23
163
938
46
151
3.28
11.47
2.7
1.9
34.4
31.2
u/l
0.41
40
121
42
136
3.30
10.70
6.4
3.2
50.2
55.4
ml/min/173m2
0.90
21
62
219
1493
1.92
10.17
8.2
4.9
7716.0
3805.0
e6/l
—
6
44
136
791
2.03
10.02
2.8
2.2
—
—
—
0
0
42
148
3.02
9.30
1.6
1.5
—
—
—
0
0
24
62
4.02
8.49
1.3
1.1
—
—
—
0
0
137
845
1.90
8.27
3.3
3.2
3349.3
2834.1
ng/l
0.30
116
737
87
466
2.07
7.83
3.3
2.7
2.5
2.5
mmol/l
0.27
75
391
216
1552
1.76
7.77
7.0
5.5
93.9
83.7
u/l
0.93
206
1398
126
782
1.85
7.34
3.4
2.4
127.5
128.2
ug/l
0.01
117
682
207
1503
1.71
6.92
32.2
18.7
14.5
14.1
%
2.77
201
1460
31
112
2.89
6.58
3.6
4.9
24.8
25.0
mmol/l
0.15
25
96
32
128
2.61
5.64
1.3
1.6
432.4
406.9
nmol/l
0.22
27
104
250
1982
1.60
5.41
29.7
14.8
31.7
30.0
mg/l
0.26
235
1624
50
250
2.12
5.35
2.5
4.0
1.0
1.0
mmol/l
0.02
38
226
221
1714
1.57
5.17
26.2
15.0
66.8
66.0
ml/min/173m2
0.21
192
1388
224
1743
1.57
5.16
4.8
4.5
2.0
2.1
mu/l
0.51
201
1501
116
770
1.68
5.14
2.9
2.6
2.3
2.4
mmol/l
0.23
98
639
189
1420
1.57
5.04
3.7
3.7
15.8
15.3
pmol/l
1.67
170
1231
41
195
2.21
4.97
2.5
2.3
8.2
13.4
umol/l
1.01
36
159
50
266
1.99
4.54
3.4
4.4
4.8
5.1
kpa
1.32
43
252
26
105
2.56
4.52
1.5
1.4
1.6
1.6
g/l
0.03
20
91
49
264
1.96
4.30
3.5
4.4
0.0
1.5
mmol/l
1.17
37
205
46
244
1.98
4.22
2.2
3.2
352.3
256.3
ng/l
0.58
40
224
49
267
1.93
4.16
3.5
4.4
10.7
11.0
kpa
0.17
43
253
134
970
1.54
4.04
6.0
3.9
112.1
67.8
ng/l
0.26
113
752
91
602
1.64
4.01
2.1
1.9
1203.4
1200.0
nmol/l
0.01
70
446
249
2062
1.47
3.82
33.1
18.9
138.9
139.5
mmol/l
1.95
243
1968
249
2067
1.46
3.74
33.2
19.0
4.0
4.0
mmol/l
1.42
243
1969
134
985
1.51
3.72
2.8
2.7
58.6
51.5
u/l
0.28
118
882
69
435
1.69
3.65
2.4
2.3
—
—
—
0
0
253
2117
1.45
3.58
38.8
22.6
123.8
129.5
g/l
6.26
246
2046
22
93
2.43
3.52
2.2
2.7
24.3
23.8
mmol/l
0.26
22
85
34
173
2.04
3.51
1.5
2.0
64.5
65.4
g/l
0.30
28
150
242
2014
1.44
3.49
11.2
8.9
21.2
22.9
u/l
0.90
229
1892
42
234
1.87
3.36
3.7
2.2
4.4
6.0
ug/l
0.52
33
187
10
27
3.75
3.35
1.3
1.3
—
—
—
0
0
17
66
2.63
3.23
1.6
1.8
0.8
0.9
g/l
0.04
12
50
17
67
2.59
3.14
1.6
1.5
3.2
3.4
g/l
—
10
52
14
50
2.85
3.09
1.3
1.4
—
—
—
0
0
16
62
2.63
3.06
1.1
1.5
35.4
35.5
g/l
—
10
49
113
851
1.44
2.68
3.9
4.4
—
—
—
0
0
45
276
1.70
2.65
1.2
1.2
0.7
1.3
u/ml
0.66
15
73
197
1636
1.36
2.61
28.9
16.9
35.4
36.4
%
0.65
133
934
17
74
2.34
2.59
1.6
1.5
—
—
—
0
0
17
74
2.34
2.59
1.6
1.5
3.6
3.8
g/l
—
10
50
17
74
2.34
2.59
1.6
1.5
6.6
8.1
g/l
1.02
11
51
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
16
69
2.36
2.49
2.6
1.9
0.3
0.3
u/ml
—
10
33
23
118
2.00
2.38
2.9
1.8
0.7
0.7
%
0.04
23
113
38
232
1.69
2.30
3.7
3.7
—
—
—
0
0
8
23
3.51
2.27
2.0
1.3
—
—
—
0
0
174
1450
1.32
2.15
4.4
3.6
20.7
16.2
mm/h
2.02
155
1287
127
1018
1.34
2.03
6.2
4.1
0.0
0.0
estimate
0.00
23
191
126
1011
1.34
2.00
7.5
5.5
0.0
0.0
estimate
0.00
24
180
55
381
1.50
2.00
1.5
1.5
4.3
1.4
mg/l
0.52
45
296
70
509
1.44
2.00
2.7
2.5
30.4
37.7
u/l
0.83
63
488
15
70
2.18
1.99
1.0
1.5
11.2
10.8
g/l
—
10
59
126
1015
1.33
1.94
5.7
3.9
0.0
0.0
estimate
0.00
21
193
52
365
1.48
1.78
2.8
3.4
0.7
0.9
ug/l
0.69
33
249
22
128
1.75
1.62
4.4
4.3
3.9
2.1
mmol/l
1.22
12
94
16
84
1.93
1.60
2.6
1.7
—
—
—
0
0
14
70
2.03
1.59
1.7
2.6
—
—
—
0
0
9
39
2.33
1.43
1.2
1.2
—
—
—
0
0
7
29
2.43
1.39
1.0
1.5
—
—
—
0
0
11
55
2.02
1.27
2.6
2.7
6.7
7.6
kpa
1.50
11
45
74
592
1.30
1.19
6.9
4.0
0.0
0.0
estimate
0.00
23
180
80
647
1.28
1.19
5.0
5.6
16.8
3.7
ug/l
0.61
70
549
5
20
2.51
1.15
1.0
1.1
—
—
—
0
0
7
30
2.35
1.12
1.7
1.7
—
—
—
0
0
206
1860
1.20
1.08
4.2
4.8
6.1
6.1
mmol/l
0.18
179
1592
64
510
1.29
1.07
3.5
4.6
21.8
22.2
%
0.06
34
273
16
97
1.67
1.07
2.8
1.7
—
—
—
0
0
5
22
2.28
1.03
1.0
1.3
—
2.4
—
0
6
9
52
1.74
0.92
2.8
1.6
—
—
—
0
0
195
1772
1.17
0.91
5.8
6.5
41.4
41.9
mmol/mol
0.28
171
1575
8
44
1.83
0.86
1.0
1.3
—
—
—
0
0
11
65
1.70
0.82
1.6
1.2
—
—
—
0
0
11
66
1.68
0.78
1.6
1.2
—
—
—
0
0
5
23
2.18
0.76
1.0
1.0
—
—
—
0
0
5
25
2.00
0.72
3.8
1.1
—
—
—
0
0
7
39
1.80
0.72
1.1
1.8
—
—
—
0
0
0
20
0.00
0.60
0.0
1.2
—
—
—
0
0
55
468
1.20
0.56
3.1
2.6
340.7
8185.8
umol/l
2.63
45
384
11
75
1.47
0.50
1.6
1.3
—
—
—
0
0
28
226
1.25
0.48
1.4
1.2
23.4
57.3
iu/ml
—
9
78
20
252
0.78
0.45
4.4
4.6
35.9
32.4
%
—
9
151
5
34
1.47
0.40
2.8
1.9
—
5.0
—
0
5
183
1729
1.09
0.39
3.8
4.2
1.4
1.5
mmol/l
0.29
152
1499
5
35
1.43
0.39
1.2
1.3
—
—
—
0
0
185
1753
1.09
0.37
3.9
4.3
4.1
4.4
mmol/l
2.43
159
1542
192
1827
1.08
0.35
4.3
4.9
2.3
2.5
mmol/l
2.60
164
1592
6
45
1.33
0.33
1.8
1.4
—
—
—
0
0
6
47
1.28
0.32
2.3
1.6
—
—
—
0
0
64
581
1.11
0.31
1.8
1.8
475.6
441.3
pmol/l
0.26
51
465
9
77
1.17
0.24
2.7
2.1
6.9
10.2
nmol/l
—
9
70
26
295
0.87
0.24
12.8
8.8
—
—
—
0
0
174
1672
1.06
0.23
3.5
3.8
1.2
1.2
mmol/l
0.12
145
1428
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
0
11
0.00
0.21
0.0
1.1
—
—
—
0
0
0
11
0.00
0.21
0.0
1.1
—
—
—
0
0
0
12
0.00
0.21
0.0
7.1
—
—
—
0
0
19
216
0.87
0.18
1.5
1.2
5.0
11.7
u/ml
—
9
70
5
61
0.81
0.08
1.0
1.1
—
—
—
0
0
13
140
0.92
0.05
1.7
1.4
—
—
—
0
0
82
827
0.99
0.02
7.5
4.3
—
—
—
0
0
14
138
1.01
0.00
1.3
1.3
—
—
—
0
0
0
6
0.00
0.00
0.0
2.2
—
1.2
—
0
6
0
6
0.00
0.00
0.0
3.2
—
214.8
—
0
6
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
0.00
0.0
1.8
—
—
—
0
0
8
79
1.01
0.00
1.0
2.5
6.9
2221.1
u/ml
—
8
69
0
5
0.00
0.00
0.0
13.4
—
14.8
—
0
5
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
103.6
—
0
7
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.6
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
Mortality – FinRegistry
↥This endpoint is excluded from FinRegistry analyses (omitted endpoint).
Relationships between endpoints
↥Index endpoint: R18_SENILITY – Senility
GWS hits: -
This endpoint is excluded from FinRegistry analyses (omitted endpoint).